One-Pot Generation of Lithium (Lithiophenyl)trialkoxyborates from Substituted Dihalobenzenes (Hal = Br, I) and Their Derivatization with Electrophiles

Paweł Kurach, Sergiusz Lulin´ski, and Janusz Serwatowski

 

 

Introduction
Recently, arylboronic acids and esters have become very popular as they are versatile building blocks in organic synthesis; they have also found applications in other fields.[1] There is a growing interest in novel functionalized derivatives. Hence, the development of new simple general synthetic routes to arylboronic acids is an important task. The classical synthetic routes to arylboronic acids involving transmetalation of aryllithium[2] or arylmagnesium[3] compounds with trialkylborates suffer from limited access to these organometallics as they do not tolerate many popular functional groups attached to the aryl ring. Very recently, a significant progress in the use of arylmagnesium reagents was achieved.[4] Many difficulties have been overcome with a discovery of palladium-catalyzed coupling of aryl halides with diboron derivatives[5] or hydroboranes.[6,7] In this context, the CuI-catalyzed coupling of iodoarenes with pinacolborane is the novel interesting alternative.[8] Aryl derivatives of silicon, mercury,[9] tin,[10] and thalium[11] have also been used in combination with borane or tribromoborane.[12] Alternative strategies relying on a structural modification of simple arylboronic acids were less explored in the past years; classical examples include nitration of phenylboronic acid and regiochemical oxidation of tolylboronic acids.[13,14] Recently, a more advanced general protocol has been developed: it involves immobilization of substituted arylboronic acids onto diethanolaminomethyl polystyrene[15] followed by derivatization of a remaining active substituent (formyl, bromomethyl, carboxy, amino groups).

 

Furthermore, N-methyliminodiacetic acid[16] and 1,8-diaminonaphthalene[17] have been employed as boron-masking reagents in the Pd-catalyzed arylation of haloarylboronic acids. The conversion of arylboronic acids into azaesters by using N-alkyldiethanolamines was used for the introduction of lithium to the boronated aromatic ring.[18] The synthesis and reactivity of closely related boron–lithium bimetallic reagents, that is, potassium 3- and 4-lithiophenyltrifluoroborates,[19] as well as magnesiated arylboronic pinacol esters were reported.[20] Our work deals with another class of lithiated tetravalent arylboron complexes, which can be easily converted into various functionalized arylboron derivatives.

 

Results and Discussion
In our first attempts, consecutive reactions were performed starting with 1,3- and 1,4-diiodobenzene: they involved lithiation with nBuLi (1 equiv.), transmetalation with B(OiPr)3 (1 equiv.), and then the second lithiation (1.1 equiv.) followed by addition of the electrophile (1.2 equiv.) (Scheme 1). To avoid a potential coupling of 1-iodobutane byproduct with iodophenyllithium and/or (lithiophenyl)triisopropoxyborate intermediates, diethyl ether was used as a solvent. After carboxylation and acidic hydrolysis, we isolated 4- and 3-carboxyphenylboronic acids, 1 and 3, respectively, in ca. 50% yield by simple solvent evaporation and washing the crude products with water and ether (Scheme 1). It should be noted that the precise control of stoichiometry during the first two steps (i.e., the first I–Li exchange and boronation) is critical for a selective generation of lithium (iodophenyl)triisopropoxyborates, which is in line with the desired removal of unreacted diiodobenzene or iodophenyllithium from the reaction mixture. Derivatization of lithium–boron reagents with appropriate electrophiles may provide access to variously functionalized arylboronic acids that are otherwise not easily accessible.

 

Thus, upon treatment with 2-methoxybenzaldehyde, boronated carbinols 2 and 4 were isolated in moderate yields. We attempted next to probe the above protocol by employing 1,3- and 1,4 dibromobenzene. Unfortunately, the corresponding lithium (bromophenyl)triisopropoxyborates do not undergo Br–Li exchange with nBuLi even at higher temperatures (around –20 °C) and by employing THF as a cosolvent, which is a better promoter of halogen–lithium exchange when compared to Et2O.[21] In fact, iodine–lithium exchange proceeds generally more smoothly than bromine–lithium exchange. To give a simple example, dilithiation of 1,3- and 1,4-diiodobenzene with nBuLi occurs quantitatively in Et2O at –78 °C, whereas 1,3- and 1,4-dibromobenzene can only be monolithiated.[22]

 

We extended our work by using dibromobenzenes bearing electron-withdrawing substituents (in terms of inductive effect), as we assumed that the better stabilization of the negative charge of the “ate” complex might be beneficial for the Br–Li interconversion. In the case of 1,4-dibromo-2-fluorobenzene, the first Br–Li exchange proceeds selectively ortho to the fluorine atom when performed in Et2O at
–80 °C to produce lithium (4-bromo-2-fluorophenyl)trialkoxyborate as a gelatinous material after consecutive boronation (Scheme 2, Table 1). To improve its solubility, the substantial addition of THF proved mandatory. Subsequent treatment with the next equivalent of nBuLi at ca–60 °C resulted in the formation of lithium (4-lithio-2-fluorophenyl)trialkoxyborate. This intermediate was trapped with selected electrophiles to give functionalized 2-fluorophenylboronic acids or their pinacol esters 5–7.

 

A similar approach proved also successful with 1,4-dibromo-2-methoxybenzene. The sequence of first lithiation/ boronation affords the “ate” complex (4-Br-2-MeOC6H3)-B(OR)3Li as a result of selective Br–Li exchange ortho to a methoxy group. However, to replace the remaining bromine atom with lithium a higher temperature, that is, ca. –40 °C, was necessary, as clearly evidenced by the precipitation of
the lithiated “ate” complex from an almost homogeneous solution. Finally, we succeeded in the isolation of 4-substituted 2-methoxyphenylboronic acids 8–10 after quench with electrophiles (Scheme 3).

In 1,3-dibromo-2-alkoxybenzenes two bromine atoms gain significant activation from the adjacent alkoxy group. Hence, the Br–Li exchange in the preformed “ate” complex (3-Br-2-ROC6H3)B(OR)3Li (R = Me, Pr) proceeds effectively at lower temperatures than in the previous case, that is, at ca. –60 °C, providing easy access to acids 11–13 (Scheme 4).

 

The reactivity pattern of 1-bromo-4-iodo-2-(trifluoromethyl)benzene is dictated by the tendency of iodine to be replaced much faster than bromine despite the fact that the latter is strongly activated by the adjacent strongly electron-withdrawing trifluoromethyl group. Thus, the iodine–lithium exchange proceeds cleanly in Et2O (importantly, THF must be completely avoided, as a mixture of products is
formed[23]) in the first step to give the “ate” complex (4-Br-3-CF3C6H3)B(OiPr)3Li after consecutive boronation. This complex undergoes facile bromine–lithium exchange at ca.–70 °C without any activation by the addition of THF. The resultant lithiated species was carboxylated to give 4-carboxy-3-(trifluoromethyl)phenylboronic acid (14) after acidic hydrolysis (Scheme 5).

 

It should be noted that in all the above cases either the anionic borate moiety is stabilized by the neighboring ortho substituent or the halogen atom in the “ate” complex is strongly ortho activated (in syntheses of 11–14). In addition, we were interested in evaluating whether long-range electron-withdrawing effects are sufficiently strong to activate the bromine atom, which would in turn result in lithiation of the borate. This prompted us to probe the reactivity of some 5-substituted 1,3-dibromobenzenes.

 

The conversion of 1,3-dibromo-5-fluorobenzene into the“ate” complexes of the type (3-Br-5-FC6H3)B(OR)3Li was performed smoothly by using Et2O at –70 °C as a solvent, whereas the addition of THF and a slight heating (to ca.–50 °C) were applied to induce the subsequent Br–Li interconversion. The resultant lithiated intermediate was trapped with CO2 to give the pinacol ester of 3-carboxy-5-
fluorophenylboronic acid 15 in moderate yield. This result demonstrates that fluorine is capable of activating remote meta positions quite strongly,[24–26] which enables an effective Br–Li exchange in the “ate” complex. An even better situation was observed for 1,3,5-tribromobenzene, where the lithiation of the “ate” complex (3,5-Br2C6H3)B(OR)3Li was observed already at –60 °C in Et2O/THF (ca. 2:1) providing compounds 16 and 17 (Scheme 6) after derivatization. Finally, the conversion of 1,3-dibromo-5-methoxybenzene into 3-carboxy-5-methoxyphenylboronic acid (18;Scheme 7) failed almost completely, as 3-bromo-5-methoxyphenylboronic acid (19) was identified as a major product, and it was only contaminated with a small amount (ca. 15%) of 18. Clearly, the lithiation of the (3-Br-5-OMeC6H3)-B(OR)3Li complex is not effective even at higher temperatures (ca. –15 °C), which confirms the reputation of the methoxy group being only weakly activating and/or anion stabilizing when located at a remote meta position,[27,28] especially in comparison with fluorine.

In addition, we investigated the thermostabilities of both types of “ate” complexes existing in the reaction pathway by using VT 11B NMR spectroscopy under reaction conditions. We selected 1,3-dibromo-2-methoxybenzene and 1,3,5-tribromobenzene (Table 1, compounds 11 and 16, respectively) as starting materials. We found that lithium (3-bromo-2-methoxyphenyl)triisopropoxyborate (δ11B =
4 ppm) is stable at 0 °C but decomposes quite rapidly at room temperature to give diisopropyl boronate (δ11B = 27 ppm). In contrast, lithium (3,5-dibromophenyl)triisopropoxyborate is more stable under comparable conditions and does not split to form the corresponding boronate. (Lithiophenyl)triisopropoxyborates are apparently too reactive when warmed up (0–20 °C), as subsequent attempted
carboxylation (at –70 °C) did not afford desired products 11 and 16. In general, this degradation could not be easily monitored by using VT 11B NMR, as only the spectra of the dianionic precursor of 11 showed changes pointing to degradation starting at ca. 0 °C, whereas for 16 they were not significantly temperature dependent.

 

Conclusions
The halogen–lithium interconversion in lithium (haloaryl)trialkoxyborates is straightforward by using nBuLi for iodides and moderately activated bromides. The resultant lithium (lithioaryl)trialkoxyborates can be regarded as equivalents of lithiated arylboronic acids or esters, which can be subsequently derivatized by the treatment with an appropriate electrophile, which provides access to a wide range of functionalized arylboronic acids and esters. It should be stressed that the proposed one-pot protocol uses readily available and relatively cheap dihalobenzenes as starting materials.

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CAS No. 101601-80-3 3-Pyridinamine, 2-phenyl- Catalog No.:AG0004YR MDL No.:MFCD04114113 MF:C11H10N2 MW:170.2105	CAS No. 101602-31-7 Quinoline, 4-chloro-6,8-dimethyl-2-phenyl- Catalog No.:AG0004YQ MDL No.: MF:C17H14ClN MW:267.7528	CAS No. 101602-51-1 Benzenemethanamine, 2-[2-(dimethylamino)ethoxy]-N-phenyl- Catalog No.:AG0004YP MDL No.: MF:C17H22N2O MW:270.3694
CAS No. 101602-77-1 3-Piperidinecarboxylic acid, 1-(1H-indol-3-ylmethyl)-, ethyl ester Catalog No.:AG0004YO MDL No.: MF:C17H22N2O2 MW:286.3688	CAS No. 1016036-76-2 Benzamide, N-[2-(dimethylamino)-3-methylbutyl]-4-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]methyl]- Catalog No.:AG0004YD MDL No.: MF:C25H30N2O4 MW:422.5167	CAS No. 101605-92-9 Ethanone, 1-(1-naphthalenyl)-, compd. with 2,4,6-trinitrophenol (1:1) Catalog No.:AG0004YN MDL No.: MF:C18H13N3O8 MW:399.3111
CAS No. 101606-18-2 [1,1'-Biphenyl]-4-amine, 4'-bromo-N-phenyl- Catalog No.:AG0004YM MDL No.: MF:C18H14BrN MW:324.2145	CAS No. 101606-42-2 3-Quinolinecarboxylic acid, 2-chloro-4-phenyl-, ethyl ester Catalog No.:AG0004YL MDL No.: MF:C18H14ClNO2 MW:311.7623	CAS No. 101606-96-6 Dibenzofuran, compd. with 2,4,6-trinitrophenol (1:1) Catalog No.:AG0004YK MDL No.: MF:C18H11N3O8 MW:397.2952
CAS No. 101607-39-0 1-Butanone, 1-[3-(2-methyl-2-buten-1-yl)-3,8-diazabicyclo[3.2.1]oct-8-yl]- Catalog No.:AG0004YJ MDL No.: MF:C15H26N2O MW:250.3797	CAS No. 101607-41-4 2,8-Diazaspiro[4.5]decane-1,3-dione, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-2-(hexahydro-1H-azepin-1-yl)-, hydrochloride (1:1) Catalog No.:AG0004YI MDL No.: MF:C23H32ClN3O4 MW:449.9709	CAS No. 101607-42-5 2,8-Diazaspiro[4.5]decane-1,3-dione, 2-(hexahydro-1H-azepin-1-yl)-8-(4-oxo-4-phenylbutyl)- Catalog No.:AG0004YH MDL No.: MF:C24H33N3O3 MW:411.5371
CAS No. 101607-43-6 2,8-Diazaspiro[4.5]decane-1,3-dione, 8-(phenylmethyl)-2-(1-piperidinyl)- Catalog No.:AG0004YG MDL No.: MF:C20H27N3O2 MW:341.4473	CAS No. 101607-44-7 2,8-Diazaspiro[4.5]decane-1,3-dione, 2-(dimethylamino)-8-[4-(4-fluorophenyl)-4-oxobutyl]- Catalog No.:AG0004YF MDL No.: MF:C20H26FN3O3 MW:375.4371	CAS No. 101607-45-8 2,8-Diazaspiro[4.5]decane-1,3-dione, 8-[4-(4-fluorophenyl)-4-oxobutyl]-2-(hexahydro-1H-azepin-1-yl)- Catalog No.:AG0004YE MDL No.: MF:C24H32FN3O3 MW:429.5276
CAS No. 10161-75-8 1,3-Benzodioxole, 5-nitro-6-propyl- Catalog No.:AG0004YY MDL No.: MF:C10H11NO4 MW:209.1986	CAS No. 10161-87-2 Benzoic acid, 4-[4-[(2-bromoacetyl)amino]butyl]- Catalog No.:AG0004YX MDL No.: MF:C13H16BrNO3 MW:314.1750	CAS No. 10161-88-3 Benzoic acid, 4-[[[4-(2-chloroacetyl)phenyl]amino]methyl]- Catalog No.:AG0004ZO MDL No.: MF:C16H14ClNO3 MW:303.7403
CAS No. 101610-44-0 Phosphine oxide, diphenyl[α-(propylsulfonyl)phenethyl]- (7CI) Catalog No.:AG0004ZL MDL No.: MF:C23H25O3PS MW:412.4816	CAS No. 101610-48-4 Phosphonium, [2-(1-methylethoxy)ethyl]triphenyl-, bromide (1:1) Catalog No.:AG0004ZK MDL No.: MF:C23H26BrOP MW:429.3297	CAS No. 101611-80-7 2-Propenal, 2-[2-(2,2-diphenylacetyl)-2,3-dihydro-3-oxo-1H-inden-1-ylidene]hydrazone Catalog No.:AG0004ZJ MDL No.: MF:C26H20N2O2 MW:392.4492
CAS No. 101615-65-0 Iodonium, bis(4-methylphenyl)-, acetate (9CI) Catalog No.:AG0004ZI MDL No.: MF:C16H17IO2 MW:368.2094	CAS No. 101615-66-1 Octanoic acid, 4-sulfophenyl ester Catalog No.:AG0004ZH MDL No.: MF:C14H20O5S MW:300.3706	CAS No. 101616-76-6 2-Pentenoic acid, 3-(3-nitrophenyl)-4-oxo-, ethyl ester Catalog No.:AG0004ZG MDL No.: MF:C13H13NO5 MW:263.2460
CAS No. 1016163-89-5 Benzoic acid, 5-bromo-2-formyl-, methyl ester Catalog No.:AG0004Z4 MDL No.:MFCD16036575 MF:C9H7BrO3 MW:243.0541	CAS No. 1016167-98-8 Pyrrolidine, 3-(1-methylethoxy)-, (3S)- Catalog No.:AG0004Z3 MDL No.:MFCD11858552 MF:C7H15NO MW:129.2001	CAS No. 1016167-99-9 Carbamic acid, N-[(3S)-3-piperidinylmethyl]-, 1,1-dimethylethyl ester Catalog No.:AG0004Z2 MDL No.:MFCD03093385 MF:C11H22N2O2 MW:214.3046
CAS No. 101617-24-7 Propanoic acid, 2-chloro-, 1,1-dimethylethyl ester, (S)- (9CI) Catalog No.:AG0004ZF MDL No.: MF:C7H13ClO2 MW:164.6299	CAS No. 101617-64-5 3-Quinolinecarbonitrile, 2-chloro-4-ethyl- Catalog No.:AG0004ZE MDL No.: MF:C12H9ClN2 MW:216.6663	CAS No. 101617-91-8 3-Quinolinecarbonitrile, 2-chloro-6-methoxy- Catalog No.:AG0004ZD MDL No.:MFCD02740422 MF:C11H7ClN2O MW:218.6391
CAS No. 101617-94-1 3-Quinolinecarbonitrile, 2-chloro-4-methyl- Catalog No.:AG0004ZC MDL No.:MFCD00833327 MF:C11H7ClN2 MW:202.6397	CAS No. 10162-73-9 Imidodicarbonimidic diamide, N,N-diphenyl-, hydrochloride (1:1) Catalog No.:AG0004ZN MDL No.: MF:C14H16ClN5 MW:289.7633	CAS No. 10162-74-0 Imidodicarbonimidic diamide, N-phenyl-N-(phenylmethyl)-, hydrochloride (1:1) Catalog No.:AG0004ZM MDL No.: MF:C15H18ClN5 MW:303.7899
CAS No. 101620-78-4 1-Piperidinebutanamine, 4-(diphenylmethoxy)- Catalog No.:AG0004ZB MDL No.: MF:C22H30N2O MW:338.4864	CAS No. 101622-02-0 Carbamothioic acid, dipropyl-, S-ethenyl ester (9CI) Catalog No.:AG0004ZA MDL No.: MF:C9H17NOS MW:187.3024	CAS No. 101622-50-8 Ethanol, 2-[[7-methyl-6-[(phenylmethyl)amino]-7H-purin-2-yl]amino]- Catalog No.:AG0004Z9 MDL No.: MF:C15H18N6O MW:298.3430
CAS No. 101622-51-9 Ethanol, 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]- Catalog No.:AG0004Z8 MDL No.:MFCD00189360 MF:C15H18N6O MW:298.3430	CAS No. 101622-52-0 7H-Purin-6-amine, 2-chloro-7-methyl-N-(phenylmethyl)- Catalog No.:AG0004Z7 MDL No.: MF:C13H12ClN5 MW:273.7209	CAS No. 101622-53-1 9H-Purin-6-amine, 2-chloro-9-methyl-N-(phenylmethyl)- Catalog No.:AG0004Z6 MDL No.: MF:C13H12ClN5 MW:273.7209
CAS No. 101622-71-3 2-Anthracenemethanesulfonic acid, 9,10-dihydro-9,10-dioxo- Catalog No.:AG0004Z5 MDL No.: MF:C15H10O5S MW:302.3019	CAS No. 1016228-01-5 Ethanone, 1-(6-bromo-3-fluoro-2-pyridinyl)- Catalog No.:AG000505 MDL No.:MFCD18258632 MF:C7H5BrFNO MW:218.0231	CAS No. 101623-20-5 2,5-Piperazinedione, 6-(hydroxymethyl)-1-methyl- Catalog No.:AG00050D MDL No.: MF:C6H10N2O3 MW:158.1552
CAS No. 101623-41-0 Oxirane, 2-[(3-methylphenoxy)methyl]-, (2S)- Catalog No.:AG00050C MDL No.:MFCD25372772 MF:C10H12O2 MW:164.2011	CAS No. 101623-68-1 Carbonic acid, 1-(acetyloxy)ethyl 4-nitrophenyl ester Catalog No.:AG00050B MDL No.: MF:C11H11NO7 MW:269.2075	CAS No. 101623-69-2 Carbonic acid, 1-chloroethyl 4-nitrophenyl ester Catalog No.:AG00050A MDL No.:MFCD19441847 MF:C9H8ClNO5 MW:245.6165
CAS No. 101623-70-5 Carbonic acid, (acetyloxy)methyl 4-nitrophenyl ester Catalog No.:AG000509 MDL No.: MF:C10H9NO7 MW:255.1810	CAS No. 1016230-29-7 3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-1-propyl- Catalog No.:AG000504 MDL No.:MFCD21603834 MF:C9H11N3O MW:177.2031	CAS No. 1016231-39-2 Boronic acid, B-(2-fluoro-3-iodophenyl)- Catalog No.:AG000503 MDL No.:MFCD05664305 MF:C6H5BFIO2 MW:265.8166
CAS No. 1016231-40-5 Boronic acid, B-(4-bromo-2,3,5,6-tetrafluorophenyl)- Catalog No.:AG000502 MDL No.:MFCD05664311 MF:C6H2BBrF4O2 MW:272.7875	CAS No. 1016232-92-0 3,3-Azetidinedimethanol, hydrochloride (1:1) Catalog No.:AG000501 MDL No.:MFCD11974385 MF:C5H12ClNO2 MW:153.6073	CAS No. 1016233-08-1 1-Azetidinecarboxylic acid, 3,3-bis(hydroxymethyl)-, 1,1-dimethylethyl ester Catalog No.:AG000500 MDL No.:MFCD24470652 MF:C10H19NO4 MW:217.2622
CAS No. 1016233-26-3 1-Azetidinecarboxylic acid, 2,4-bis(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R,4S)- Catalog No.:AG0004ZZ MDL No.: MF:C10H19NO4 MW:217.2622	CAS No. 1016234-87-9 Phenol, 4-bromo-5-fluoro-2-nitro- Catalog No.:AG0004ZY MDL No.:MFCD14583144 MF:C6H3BrFNO3 MW:235.9953	CAS No. 1016234-89-1 Phenol, 2-amino-4-bromo-5-fluoro- Catalog No.:AG0004ZX MDL No.:MFCD11101429 MF:C6H5BrFNO MW:206.0124
CAS No. 101624-23-1 Propanal, 3-chloro-2,2-dimethyl-, oxime Catalog No.:AG000508 MDL No.: MF:C5H10ClNO MW:135.5920	CAS No. 101624-26-4 3-Indolizinecarboxaldehyde, 2-(4-methoxyphenyl)- Catalog No.:AG000507 MDL No.:MFCD05178272 MF:C16H13NO2 MW:251.2799	CAS No. 1016241-64-7 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid Catalog No.:AG0004ZW MDL No.:MFCD11518909 MF:C7H5N3O2 MW:163.1335
CAS No. 1016241-80-7 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro- Catalog No.:AG0004ZV MDL No.:MFCD11518907 MF:C7H4ClN3O2 MW:197.5786	CAS No. 1016241-81-8 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-fluoro- Catalog No.:AG0004ZU MDL No.: MF:C7H4FN3O2 MW:181.1240	CAS No. 1016241-84-1 5H-Pyrrolo[2,3-b]pyrazine-6-carboxylic acid, 2-fluoro- Catalog No.:AG0004ZT MDL No.: MF:C7H4FN3O2 MW:181.1240
CAS No. 1016241-85-2 5H-Pyrrolo[2,3-b]pyrazine-6-carboxylic acid, 2-fluoro-, ethyl ester Catalog No.:AG0004ZS MDL No.: MF:C9H8FN3O2 MW:209.1771	CAS No. 101625-35-8 Naphtho[2,3-d]-1,3-dioxol-6-amine, 5,6,7,8-tetrahydro- Catalog No.:AG000506 MDL No.:MFCD18651085 MF:C11H13NO2 MW:191.2264	CAS No. 1016258-17-5 Cyclohexaneacetic acid, 1-amino-, methyl ester, hydrochloride (1:1) Catalog No.:AG0004ZR MDL No.:MFCD08690704 MF:C9H18ClNO2 MW:207.6977
CAS No. 1016258-66-4 1,4-Piperidinedicarboxylic acid, 4-cyano-, 1-(1,1-dimethylethyl) 4-ethyl ester Catalog No.:AG0004ZQ MDL No.:MFCD15144556 MF:C14H22N2O4 MW:282.3355	CAS No. 1016258-69-7 1,4-Piperidinedicarboxylic acid, 4-(aminomethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester Catalog No.:AG0004ZP MDL No.:MFCD14525454 MF:C14H26N2O4 MW:286.3672	CAS No. 1016259-54-3 1,4-Piperidinedicarboxylic acid, 3-[(1-phenylethyl)amino]-, 1-(1,1-dimethylethyl) 4-ethyl ester Catalog No.:AG00050F MDL No.:MFCD18911735 MF:C21H32N2O4 MW:376.4898
CAS No. 101626-68-0 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, calcium salt (1:1) Catalog No.:AG00050U MDL No.: MF:C19H15CaNO7 MW:409.4029	CAS No. 101626-70-4 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)- Catalog No.:AG00050T MDL No.: MF:C10H15N3S MW:209.3112	CAS No. 101626-73-7 1H-Imidazole, 4,5-dihydro-2-[[[2-(1-methylethyl)phenyl]thio]methyl]-, hydrochloride (1:1) Catalog No.:AG00050S MDL No.: MF:C13H19ClN2S MW:270.8214
CAS No. 101629-11-2 4(1H)-Pteridinone, 5,6,7,8-tetrahydro-6,7-dimethyl-, (6R-cis)- (9CI) Catalog No.:AG00050R MDL No.: MF:C8H12N4O MW:180.2071	CAS No. 10163-15-2 Phosphorofluoridic acid, disodium salt (8CI,9CI) Catalog No.:AG000512 MDL No.:MFCD00014248 MF:FNa2O3P MW:143.9499	CAS No. 10163-32-3 Ethanol, 2-[(3,5,6-trichloro-2-pyridinyl)oxy]- Catalog No.:AG000511 MDL No.: MF:C7H6Cl3NO2 MW:242.4870
CAS No. 10163-34-5 4-Pyridinol, 2,3,5,6-tetrabromo- Catalog No.:AG000510 MDL No.: MF:C5HBr4NO MW:410.6835	CAS No. 10163-83-4 Pregn-5-en-20-one, 11-(acetyloxy)-3,14-dihydroxy-12-(3-methyl-1-oxobutoxy)-, (3β,11α,12β,14β)- Catalog No.:AG00050Z MDL No.:MFCD01756714 MF:C28H42O7 MW:490.6289	CAS No. 101630-94-8 Propanamide, N,N'-2,6-pyridinediylbis[2,2-dimethyl- Catalog No.:AG00050Q MDL No.:MFCD00416154 MF:C15H23N3O2 MW:277.3620
CAS No. 1016315-12-0 Quinoline, 2-chloro-5-(phenylmethoxy)- Catalog No.:AG00050E MDL No.:MFCD20482427 MF:C16H12ClNO MW:269.7256	CAS No. 101634-82-6 Benzene, 1,1'-(1,2-diphenyl-1,2-ethenediyl)bis[4-chloro- Catalog No.:AG00050P MDL No.: MF:C26H18Cl2 MW:401.3271	CAS No. 101637-69-8 2-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-6-hydroxy-, ethyl ester Catalog No.:AG00050O MDL No.: MF:C13H16O3 MW:220.2643
CAS No. 101637-76-7 Phenol, 4-[(2-chloroethyl)thio]- Catalog No.:AG00050N MDL No.: MF:C8H9ClOS MW:188.6745	CAS No. 101639-95-6 7-Octenoyl chloride Catalog No.:AG00050M MDL No.: MF:C8H13ClO MW:160.6412	CAS No. 10164-64-4 2-Propanol, 1-amino-, triester with boric acid (H3BO3) (9CI) Catalog No.:AG00050Y MDL No.: MF:C9H24BN3O3 MW:233.1162
CAS No. 10164-73-5 Prost-13-en-1-oic acid, 9,11,15-trihydroxy-, (9β,11α,13E,15S)- Catalog No.:AG00050X MDL No.:MFCD00135223 MF:C20H36O5 MW:356.4968	CAS No. 10164-84-8 4-Thiazolidinone, 2-(2-chlorophenyl)-3-(2-pyridinyl)- Catalog No.:AG00050W MDL No.: MF:C14H11ClN2OS MW:290.7679	CAS No. 10164-86-0 4-Thiazolidinone, 2-(4-chlorophenyl)-3-(2-pyridinyl)- Catalog No.:AG00050V MDL No.: MF:C14H11ClN2OS MW:290.7679
CAS No. 101640-70-4 2H-Pyran-4-carboxylic acid, 2-oxo-6-(trifluoromethyl)-, methyl ester Catalog No.:AG00050L MDL No.: MF:C8H5F3O4 MW:222.1181	CAS No. 101641-07-0 Benzaldehyde, 3,5-dimethoxy-4-[(2-methoxyethoxy)methoxy]- Catalog No.:AG00050K MDL No.: MF:C13H18O6 MW:270.2784	CAS No. 101642-77-7 Propanoic acid, 2-methyl-3-[[(phenylmethoxy)carbonyl]amino]- Catalog No.:AG00050J MDL No.:MFCD02094551 MF:C12H15NO4 MW:237.2518
CAS No. 101646-01-9 Benzene, 1,2-difluoro-3-nitro-5-(trifluoromethyl)- Catalog No.:AG00050I MDL No.:MFCD00236668 MF:C7H2F5NO2 MW:227.0883	CAS No. 101646-02-0 Benzene, 1-chloro-2-fluoro-3-nitro-5-(trifluoromethyl)- Catalog No.:AG00050H MDL No.:MFCD00674108 MF:C7H2ClF4NO2 MW:243.5429	CAS No. 101646-12-2 Benzoic acid, 2,2'-[[1,3-dioxo-2-(phenylmethylene)-1,3-propanediyl]diimino]bis-, bis(1,1-dimethylethyl) ester (9CI) Catalog No.:AG00051K MDL No.: MF:C32H34N2O6 MW:542.6222
CAS No. 101648-17-3 2H-1,2,3-Triazole, 2-(4-nitrophenyl)-4,5-diphenyl- Catalog No.:AG00051J MDL No.: MF:C20H14N4O2 MW:342.3508	CAS No. 101649-40-5 1-Propanone, 2-hydroxy-2-methyl-1-[4-(1-methylethenyl)phenyl]- Catalog No.:AG00051I MDL No.: MF:C13H16O2 MW:204.2649	CAS No. 101649-82-5 Acetic acid, 2-(benzoylamino)-2-bromo-, methyl ester Catalog No.:AG00051H MDL No.: MF:C10H10BrNO3 MW:272.0953
CAS No. 1016492-54-8 Hydrazine, [1-(3-bromophenyl)ethyl]- Catalog No.:AG000518 MDL No.: MF:C8H11BrN2 MW:215.0903	CAS No. 1016493-25-6 Benzenesulfonamide, N-butyl-3-cyano- Catalog No.:AG000517 MDL No.: MF:C11H14N2O2S MW:238.3061	CAS No. 1016496-17-5 Benzenemethanamine, 5-bromo-2-fluoro-N-propyl- Catalog No.:AG000516 MDL No.:MFCD09927562 MF:C10H13BrFN MW:246.1193
CAS No. 1016496-87-9 Hydrazine, [1-(2-methoxyphenyl)ethyl]- Catalog No.:AG000515 MDL No.: MF:C9H14N2O MW:166.2203	CAS No. 1016498-51-3 1H-Inden-4-ol, 3-hydrazinyl-2,3-dihydro-1,7-dimethyl- Catalog No.:AG000514 MDL No.: MF:C11H16N2O MW:192.2575	CAS No. 1016498-93-3 Hydrazine, [1-(2-benzofuranyl)ethyl]- Catalog No.:AG000513 MDL No.: MF:C10H12N2O MW:176.2151
CAS No. 10165-09-0 Aziridine, 1-[(methylthio)methyl]- Catalog No.:AG00051R MDL No.: MF:C4H9NS MW:103.1860	CAS No. 10165-13-6 Aziridine, 1-chloro- Catalog No.:AG00051Q MDL No.: MF:C2H4ClN MW:77.5129	CAS No. 10165-25-0 Acetamide, N-(4-chloro-9,10-dihydro-9,10-dioxo-1-anthracenyl)- Catalog No.:AG00051P MDL No.: MF:C16H10ClNO3 MW:299.7085
CAS No. 10165-29-4 9,10-Anthracenedione, 1-amino-3-bromo-2-methyl- Catalog No.:AG00051O MDL No.: MF:C15H10BrNO2 MW:316.1494	CAS No. 10165-31-8 9,10-Anthracenedione, 1,4-diamino-2-bromo- Catalog No.:AG00051N MDL No.: MF:C14H9BrN2O2 MW:317.1375	CAS No. 10165-86-3 3-Pyridinecarboxylic acid, 6-formyl-, methyl ester Catalog No.:AG00051M MDL No.:MFCD08275010 MF:C8H7NO3 MW:165.1461
CAS No. 10165-99-8 1(2H)-Isoquinolinone, 2-(2-phenylethyl)- Catalog No.:AG00051L MDL No.: MF:C17H15NO MW:249.3071	CAS No. 101650-09-3 Heptanoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (2S)- Catalog No.:AG00051G MDL No.: MF:C16H23NO4 MW:293.3581	CAS No. 101650-14-0 Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-iodo-, methyl ester, (2S)- Catalog No.:AG00051F MDL No.:MFCD16294352 MF:C10H18INO4 MW:343.1587
CAS No. 101650-17-3 Butanoic acid, 2-amino-4-bromo-, methyl ester, (2S)- Catalog No.:AG00051E MDL No.: MF:C5H10BrNO2 MW:196.0424	CAS No. 101650-18-4 1,3-Dioxolane, 2-(3-bromopropyl)-2-propyl- Catalog No.:AG00051D MDL No.: MF:C9H17BrO2 MW:237.1341	CAS No. 101650-46-8 Piperidine, 1-[[3-(3-chloropropoxy)phenyl]methyl]- Catalog No.:AG00051C MDL No.: MF:C15H22ClNO MW:267.7943
CAS No. 101650-63-9 Indolizine, 6-ethynyl-2-methyl- Catalog No.:AG00051B MDL No.:MFCD28659995 MF:C11H9N MW:155.1959	CAS No. 101650-66-2 Indolizine, 6-ethynyl-2-methyl-3-(2-phenyldiazenyl)- Catalog No.:AG00051A MDL No.: MF:C17H13N3 MW:259.3052	CAS No. 101650-77-5 Dodecanoic acid, 12,12-dimethoxy-9-oxo-, methyl ester Catalog No.:AG000519 MDL No.: MF:C15H28O5 MW:288.3798
CAS No. 1016500-11-0 Hydrazine, [(2,5-dimethyl-3-furanyl)methyl]- Catalog No.:AG00051Y MDL No.: MF:C7H12N2O MW:140.1830	CAS No. 1016500-71-2 Phenol, 4-chloro-2-[(ethylamino)methyl]- Catalog No.:AG00051X MDL No.:MFCD09932367 MF:C9H12ClNO MW:185.6507	CAS No. 1016501-27-1 4-Pyridinecarbonitrile, 2-(4-methyl-1-piperazinyl)- Catalog No.:AG00051W MDL No.:MFCD09932504 MF:C11H14N4 MW:202.2557
CAS No. 1016502-10-5 Hydrazine, [1-[2-(trifluoromethyl)phenyl]ethyl]- Catalog No.:AG00051V MDL No.: MF:C9H11F3N2 MW:204.1922	CAS No. 1016506-84-5 Benzenemethanamine, α-(4-bromophenyl)-3-fluoro- Catalog No.:AG00051U MDL No.:MFCD09815842 MF:C13H11BrFN MW:280.1355	CAS No. 1016507-27-9 5-Benzoxazolamine, 2-(2-bromo-5-fluorophenyl)- Catalog No.:AG00051T MDL No.:MFCD09929466 MF:C13H8BrFN2O MW:307.1178
CAS No. 1016509-13-9 Benzenemethanamine, 3-(methylsulfonyl)-α-phenyl- Catalog No.:AG00051S MDL No.:MFCD09817373 MF:C14H15NO2S MW:261.3394	CAS No. 101651-31-4 Benzeneacetamide, 4-ethoxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]- Catalog No.:AG00052F MDL No.: MF:C18H21NO4 MW:315.3636	CAS No. 101651-37-0 Acetamide, N-(3-methoxyphenyl)-N-phenyl- Catalog No.:AG00052E MDL No.: MF:C15H15NO2 MW:241.2851
CAS No. 101651-51-8 Acetamide, N,N'-[4-(2-propenyloxy)-1,3-phenylene]bis- (9CI) Catalog No.:AG00052D MDL No.: MF:C13H16N2O3 MW:248.2777	CAS No. 101651-55-2 Acetamide, 2-[[2-(diethylamino)ethyl](phenylmethyl)amino]-N-phenyl-, hydrochloride (1:2) Catalog No.:AG00052C MDL No.: MF:C21H31Cl2N3O MW:412.3963	CAS No. 101651-56-3 Acetamide, N-[3-[2-[bis(2-bromoethyl)amino]ethyl]-4-methoxyphenyl]- Catalog No.:AG00052B MDL No.: MF:C15H22Br2N2O2 MW:422.1554
CAS No. 101651-57-4 Acetamide, N-[3-[2-[bis(2-chloroethyl)amino]ethyl]-4-ethoxyphenyl]- Catalog No.:AG00052A MDL No.: MF:C16H24Cl2N2O2 MW:347.2800	CAS No. 101651-60-9 Acetamide, N-(2-chlorophenyl)-2-[[2-(diethylamino)ethyl]ethylamino]-, hydrochloride (1:2) Catalog No.:AG000529 MDL No.: MF:C16H28Cl3N3O MW:384.7720	CAS No. 101651-61-0 Acetamide, N-(2-chlorophenyl)-2-[[2-(diethylamino)ethyl]thio]-, hydrochloride (1:1) Catalog No.:AG000528 MDL No.: MF:C14H22Cl2N2OS MW:337.3083
CAS No. 101651-64-3 Acetamide, N-(2-chlorophenyl)-2-[ethyl[2-(1-piperidinyl)ethyl]amino]-, hydrochloride (1:2) Catalog No.:AG000527 MDL No.: MF:C17H28Cl3N3O MW:396.7827	CAS No. 101651-66-5 Acetamide, N-(2-chlorophenyl)-2-[methyl[2-(1-piperidinyl)ethyl]amino]-, hydrochloride (1:2) Catalog No.:AG000526 MDL No.: MF:C16H26Cl3N3O MW:382.7561	CAS No. 101651-69-8 Acetamide, N-(2,6-dichlorophenyl)-2-[[2-(diethylamino)ethyl]thio]-, hydrochloride (1:1) Catalog No.:AG000525 MDL No.: MF:C14H21Cl3N2OS MW:371.7533
CAS No. 101651-71-2 Acetamide, 2-(diethylamino)-N-(2-ethylphenyl)-, hydrochloride (1:1) Catalog No.:AG000524 MDL No.: MF:C14H23ClN2O MW:270.7982	CAS No. 101651-72-3 Benzeneacetamide, N-[(1-methyl-3-piperidinyl)methyl]-N,α-diphenyl-, hydriodide (1:1) Catalog No.:AG000523 MDL No.: MF: MW:	CAS No. 101651-73-4 Acetamide, N-(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)-N-phenyl- Catalog No.:AG000522 MDL No.: MF:C19H30N2O MW:302.4543
CAS No. 101651-74-5 Acetamide, N-[4-[(2-pyridinylamino)sulfonyl]phenyl]-, sodium salt (1:1) Catalog No.:AG000521 MDL No.: MF:C13H13N3NaO3S MW:314.3154	CAS No. 101651-76-7 Acetic acid, 2-[2-[3-(acetylamino)-2,4,6-triiodophenoxy]ethoxy]-, sodium salt (1:1) Catalog No.:AG000520 MDL No.: MF:C12H11I3NNaO5 MW:652.9226	CAS No. 101651-79-0 1-Piperidineacetamide, N-ethyl-2-methyl-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1) Catalog No.:AG00051Z MDL No.: MF:C19H31ClN2O2 MW:354.9146
CAS No. 101651-80-3 2H-Indol-2-one, 3-(2-aminopropyl)-1,3-dihydro-3-hydroxy- Catalog No.:AG000533 MDL No.: MF:C11H14N2O2 MW:206.2411	CAS No. 1016510-27-2 Hydrazine, [1-(2,5-dichlorophenyl)ethyl]- Catalog No.:AG000531 MDL No.: MF:C8H10Cl2N2 MW:205.0844	CAS No. 1016511-14-0 Hydrazine, [1-(5-methyl-2-thienyl)ethyl]- Catalog No.:AG000530 MDL No.: MF:C7H12N2S MW:156.2486
CAS No. 1016511-83-3 Hydrazine, (1-cyclopropylethyl)- Catalog No.:AG00052Z MDL No.:MFCD09745702 MF:C5H12N2 MW:100.1622	CAS No. 1016513-70-4 Propanimidamide, 3-(diethylamino)- Catalog No.:AG00052Y MDL No.:MFCD09745067 MF:C7H17N3 MW:143.2300	CAS No. 1016515-23-3 Hydrazine, [1-(2-methoxy-5-methylphenyl)ethyl]- Catalog No.:AG00052X MDL No.: MF:C10H16N2O MW:180.2468
CAS No. 1016515-54-0 Benzenesulfonamide, 3-(aminomethyl)-N-butyl- Catalog No.:AG00052W MDL No.: MF:C11H18N2O2S MW:242.3378	CAS No. 1016516-10-1 Hydrazine, [2-(2-naphthalenyl)ethyl]- Catalog No.:AG00052V MDL No.:MFCD09811782 MF:C12H14N2 MW:186.2530	CAS No. 1016516-29-2 Benzenesulfonyl chloride, 3,5-dimethyl-4-(phenylmethoxy)- Catalog No.:AG00052U MDL No.:MFCD09802689 MF:C15H15ClO3S MW:310.7958
CAS No. 1016516-68-9 Benzenesulfonyl chloride, 2-fluoro-4-methoxy- Catalog No.:AG00052T MDL No.:MFCD09803246 MF:C7H6ClFO3S MW:224.6371	CAS No. 1016516-96-3 Hydrazine, (cyclopentylmethyl)- Catalog No.:AG00052S MDL No.:MFCD09816312 MF:C6H14N2 MW:114.1888	CAS No. 1016517-47-7 Hydrazine, [(2,3-dimethylphenyl)methyl]- Catalog No.:AG00052R MDL No.: MF:C9H14N2 MW:150.2209
CAS No. 1016519-42-8 Thiazole, 5-(hydrazinylmethyl)-4-methyl- Catalog No.:AG00052Q MDL No.: MF:C5H9N3S MW:143.2101	CAS No. 1016519-61-1 Glycine, N-methyl-N-2-pyridinyl- Catalog No.:AG00052P MDL No.:MFCD09932969 MF:C8H10N2O2 MW:166.1772	CAS No. 101652-74-8 Acetonitrile, 2-(trimethylgermyl)-2-(trimethylsilyl)- Catalog No.:AG000532 MDL No.: MF:C8H19GeNSi MW:229.9687
CAS No. 1016523-02-6 Phenol, 4-(1-hydrazinylpropyl)- Catalog No.:AG00052O MDL No.: MF:C9H14N2O MW:166.2203	CAS No. 1016523-08-2 Hydrazine, [(5-ethoxy-2,3-dihydro-2-methyl-6-benzofuranyl)methyl]- Catalog No.:AG00052N MDL No.: MF:C12H18N2O2 MW:222.2835	CAS No. 1016523-43-5 Hydrazine, [(2-methyl-3-furanyl)methyl]- Catalog No.:AG00052M MDL No.: MF:C6H10N2O MW:126.1564
CAS No. 1016523-59-3 Benzenamine, 3-[(4-methoxyphenoxy)methyl]- Catalog No.:AG00052L MDL No.:MFCD09811389 MF:C14H15NO2 MW:229.2744	CAS No. 1016524-58-5 Phenol, 3-(1-hydrazinylethyl)- Catalog No.:AG00052K MDL No.: MF:C8H12N2O MW:152.1937	CAS No. 1016524-78-9 3-Pyridinecarboxylic acid, 2-(4-oxo-1-piperidinyl)-, ethyl ester Catalog No.:AG00052J MDL No.:MFCD09930005 MF:C13H16N2O3 MW:248.2777
CAS No. 1016526-12-7 Hydrazine, [1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)ethyl]- Catalog No.:AG00052I MDL No.: MF:C11H16N2O2 MW:208.2569	CAS No. 1016526-47-8 Hydrazine, [1-(3-ethyl-2-benzofuranyl)ethyl]- Catalog No.:AG00052H MDL No.: MF:C12H16N2O MW:204.2682	CAS No. 1016526-56-9 Hydrazine, [1-(3-fluorophenyl)ethyl]- Catalog No.:AG00052G MDL No.: MF:C8H11FN2 MW:154.1847
CAS No. 1016526-90-1 Hydrazine, [4-(2-thienyl)butyl]- Catalog No.:AG00053L MDL No.: MF:C8H14N2S MW:170.2752	CAS No. 1016528-76-9 Hydrazine, [(2,5-dimethylphenyl)phenylmethyl]- Catalog No.:AG00053K MDL No.: MF:C15H18N2 MW:226.3168	CAS No. 1016529-12-6 Hydrazine, [[4-[(trifluoromethyl)thio]phenyl]methyl]- Catalog No.:AG00053J MDL No.: MF:C8H9F3N2S MW:222.2307
CAS No. 1016529-46-6 Pyrrolidine, 2-(2,6-difluorophenyl)- Catalog No.:AG00053I MDL No.:MFCD09809920 MF:C10H11F2N MW:183.1978	CAS No. 1016529-86-4 Hydrazine, [1-[2-(difluoromethoxy)phenyl]ethyl]- Catalog No.:AG00053H MDL No.: MF:C9H12F2N2O MW:202.2012	CAS No. 1016529-98-8 Hydrazine, [[3-(difluoromethoxy)-4-methoxyphenyl]methyl]- Catalog No.:AG00053G MDL No.: MF:C9H12F2N2O2 MW:218.2006
CAS No. 1016530-40-7 2-Piperidinone, 1-[4-amino-3-(trifluoromethyl)phenyl]- Catalog No.:AG00053F MDL No.: MF:C12H13F3N2O MW:258.2396	CAS No. 1016530-78-1 Hydrazine, [1-[3-(trifluoromethyl)phenyl]ethyl]- Catalog No.:AG00053E MDL No.: MF:C9H11F3N2 MW:204.1922	CAS No. 1016530-98-5 Pyrazine, 2-chloro-6-(2,2,2-trifluoroethoxy)- Catalog No.:AG00053D MDL No.:MFCD09809858 MF:C6H4ClF3N2O MW:212.5570
CAS No. 1016531-68-2 Pyridine, 2-[(2-bromophenoxy)methyl]- Catalog No.:AG00053C MDL No.:MFCD09927519 MF:C12H10BrNO MW:264.1179	CAS No. 1016532-35-6 Hydrazine, [1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]- Catalog No.:AG00053B MDL No.: MF:C10H14N2O2 MW:194.2304	CAS No. 1016533-50-8 Phenol, 4-(1-hydrazinylethyl)- Catalog No.:AG00053A MDL No.: MF:C8H12N2O MW:152.1937
CAS No. 1016533-62-2 Benzamide, 2-(3-aminopropoxy)- Catalog No.:AG000539 MDL No.:MFCD09806522 MF:C10H14N2O2 MW:194.2304	CAS No. 1016533-76-8 Pyrazine, 2-(hydrazinylmethyl)-5-methyl- Catalog No.:AG000538 MDL No.: MF:C6H10N4 MW:138.1704	CAS No. 1016534-59-0 Pyridine, 2-chloro-5-(methoxymethyl)- Catalog No.:AG000537 MDL No.:MFCD09802660 MF:C7H8ClNO MW:157.5975
CAS No. 1016535-83-3 Benzeneacetonitrile, 4-[(4-fluorophenyl)methoxy]- Catalog No.:AG000536 MDL No.: MF:C15H12FNO MW:241.2603	CAS No. 1016536-08-5 Benzonitrile, 4-(1-hydrazinylethyl)- Catalog No.:AG000535 MDL No.: MF:C9H11N3 MW:161.2037	CAS No. 1016536-64-3 Hydrazine, [(6-methoxy-2-naphthalenyl)methyl]- Catalog No.:AG000534 MDL No.: MF:C12H14N2O MW:202.2524
CAS No. 101654-29-9 Heptane, 4-(bromomethyl)- Catalog No.:AG00053M MDL No.:MFCD02262152 MF:C8H17Br MW:193.1246