Catalytic asymmetric dearomatization (CADA) reaction-enabled total synthesis of indole-based natural products

Chao Zheng and Shu-Li You

 

 

1. Introduction
The positive interplay between the studies on natural product synthesis and synthetic methodology development constitutes the major theme of fundamental organic chemistry. The fascinating structures of various natural products serve as the inspiration and driving force of endless emerging and evolving unprecedented synthetic methods. On the other hand, natural product synthesis is generally regarded as a premier stage, where a synthetic method can exhibit its practicality and robustness.

 

Indole-based polycyclic structures have constantly received intensive research interests due to their wide occurrence in numerous alkaloids that possess diverse biological activities Dearomatization of indole derivatives has long been viewed as an attractive strategy to readily access sophisticated spiro or fused polycyclic indoline scaffolds. Accordingly, Qin et al. developed an elegant cascade (or stepwise) reaction of cyclopropanation/ring-opening/iminium (CRI) cyclization of tryptamine derivatives, which enables the efficient assembly of a variety of indoline alkaloids.8 Meanwhile, Ma and co-workers
carried out systematic studies on intramolecular dearomative oxidative coupling (IDOC) reactions of indoles and accomplished the total synthesis of many indoline alkaloids.

 

In recent years, catalytic asymmetric dearomatization (CADA) reactions have been recognized as powerful methods for the conversion of readily available planar aromatic feedstocks to three-dimensional polycyclic molecules.10–18 Particularly, the synthesis of many indole-based natural products becomes viable with the key ring system and the stereochemistry being established via a CADA reaction. A major advantage of these syntheses is that they do not rely on the chiral pool strategy. The absolute conguration of the product is solely controlled by the chiral catalyst. Therefore, not only natural products themselves, but also their corresponding unnatural enantiomers, diastereoisomers, and even libraries of analogs can be easily synthesized, which is of great importance in medicinal chemistry.

 

Herein, we summarize the most recent progress on the total synthesis of indole-based natural products enabled by an asymmetric dearomatization reaction as the key step (Fig. 1). Several ring-forming strategies for the construction of key polycyclic scaffolds will be rst highlighted. Then, the various applications of asymmetric dearomatization reactions in the total syntheses of these natural products will be discussed accordingly. Finally, we present a personal perspective of this dynamic researcheld.

 

2. General strategies for the formation of key ring systems
In general, a series of ring-formation strategies have been developed in the total synthesis of indole-based natural products via a CADA reaction (Fig. 2). Most of these strategies take advantage of
the inherent strong nucleophilicity of the C3 position of 3-substituted indoles and the electrophilicity of 3,3-disubstituted indolenine cations (types I to IV). By devising appropriately tethered nucleophiles and electrophiles, cascade cyclization reactions may be triggered. On the other hand, the recent enantioselective total synthesis of (+)-hinckdentine A involved a dearomative Hecktype cyclization, which can be regarded as the connection between the C2 position of indole with an electrophile (type V). Notably, the asymmetric dearomatization of indole derivatives via a visiblelight-mediated sequential single-electron transfer process has also emerged, which allowed the formal installation of an external nucleophile at the C3 position of indole with concomitant cyclization (type VI). By employing these strategies, spiro, fused, and even bridged polycyclic scaffolds can be assembled by carefully manipulating the reaction sequence. In the following sections, detailed discussions will be presented on how these strategies have been applied in the construction of the core structures of indole-based natural products.

3. Type I cyclization
The most frequently employed strategy takes advantage of indole substrates possessing a pendant nucleophile on the C3 position, where tryptamine/tryptophol derivatives are among the commonly used substrates. A Friedel–Cras-type addition with an external electrophile generates a 3,3-disubstituted indolenine intermediate whose iminium moiety is readily trapped by the nucleophilic side chain, yielding the corresponding hexahydropyrrolo[2,3-b]indole (HPI) or tetrahydro-2H-furo[2,3-b]indole core structures, which lays a solid foundation for further synthetic elaborations.

In the past several years, signicant contributions have been made in the area of catalytic asymmetric dearomatization reactions, which have brought to the synthetic community a series of novel disconnection strategies in the total synthesis of diverse natural products. As the most prominent examples, many elegant asymmetric total syntheses of indole-based polycyclic alkaloids have been reported. As presented in the previous sections, these syntheses take advantages of both rational design of the substrates and the newly disclosed reactivity under the theme of catalytic asymmetric dearomatization.

 

Undoubtedly, these achievements will stimulate further investigations in related areas. We believe that future studies may be focused on the application of more strategies in catalytic asymmetric dearomatization. Most of the syntheses discussed herein largely rely on the manipulations of the nucleophilicity/electrophilicity of the substituted indole substrates at the ipso position. However, the rapid development of visible-lightmediated reactions via the single-electron transfer process provide new possibilities for exploring asymmetric dearomatization reactions, which have been exemplied by the recent studies from Knowles' group.93 In addition, Sarlah and coworkers performed systematic studies on visible-lightmediated dearomatization of substituted benzenes with an arenophile, which pave the way for the efficient synthesis of diverse natural products.

 

Overall, considering that continuing developments are being made in the area of catalytic asymmetric dearomatization reactions, we feel quite condent that this powerful strategy will end broad applications in the journey of natural product total synthesis.

Angene offers over 100,000 products in one convenient, easy-to-use site, you're sure to find everything you're looking for on www.AngeneChem.com:

CAS No. 10180-07-1 1H-Pyrazole, 4,5-dihydro-3,5-bis(4-methoxyphenyl)-1-phenyl- Catalog No.:AG0005MH MDL No.: MF:C23H22N2O2 MW:358.4330	CAS No. 10181-37-0 3-Acridinamine, 9-(4-aminophenyl)-, nitrate (1:1) Catalog No.:AG0005MG MDL No.: MF:C19H16N4O3 MW:348.3553	CAS No. 10181-56-3 1,3-Cyclobutanedithione, 2,2,4,4-tetramethyl- Catalog No.:AG0005MF MDL No.: MF:C8H12S2 MW:172.3109
CAS No. 10181-59-6 Cyclobutanone, 2,2,4,4-tetramethyl-3-thioxo- Catalog No.:AG0005ME MDL No.:MFCD16876707 MF:C8H12OS MW:156.2453	CAS No. 10181-73-4 Benzene, (cyclopentylsulfinyl)- Catalog No.:AG0005MD MDL No.: MF:C11H14OS MW:194.2933	CAS No. 10181-78-9 Propanamine, N-chloro-1,1,1,3,3,3-hexafluoro- Catalog No.:AG0005MC MDL No.: MF:C3ClF6N MW:199.4822
CAS No. 10181-92-7 Phenol, 4-(2,6-dimethylphenoxy)- Catalog No.:AG0005MB MDL No.:MFCD22570376 MF:C14H14O2 MW:214.2598	CAS No. 10181-93-8 Phenol, 4-(4-methoxyphenoxy)- Catalog No.:AG0005MA MDL No.: MF:C13H12O3 MW:216.2326	CAS No. 10181-94-9 Phenol, 4-(4-phenoxyphenoxy)- Catalog No.:AG0005M9 MDL No.: MF:C18H14O3 MW:278.3020
CAS No. 101817-45-2 Glycinamide, N-[4-(9-acridinylamino)-1-oxobutyl]-L-tyrosyl-L-lysyl-L-lysyl-N-[3-(9-acridinylamino)propyl]-, tetraformate (salt) (9CI) Catalog No.:AG0005N0 MDL No.: MF: MW:	CAS No. 101817-80-5 Methanesulfonic acid, 1,1-difluoro-, difluoromethyl ester Catalog No.:AG0005MZ MDL No.: MF:C2H2F4O3S MW:182.0941	CAS No. 101819-36-7 1H-Inden-1-one, 6-chloro-2,3-dihydro-7-hydroxy- Catalog No.:AG0005MY MDL No.: MF:C9H7ClO2 MW:182.6037
CAS No. 101819-48-1 1H-Inden-1-one, 6-bromo-2,3-dihydro-7-hydroxy- Catalog No.:AG0005MX MDL No.: MF:C9H7BrO2 MW:227.0547	CAS No. 101819-51-6 1(2H)-Naphthalenone, 5-bromo-3,4-dihydro-8-hydroxy- Catalog No.:AG0005MW MDL No.: MF:C10H9BrO2 MW:241.0813	CAS No. 101819-99-2 Phenol, 6-amino-2,4-dichloro-3-ethyl-, hydrochloride (1:1) Catalog No.:AG0005MV MDL No.:MFCD00270793 MF:C8H10Cl3NO MW:242.5301
CAS No. 10182-03-3 Propanedinitrile, 2-(6-methoxy-1-methyl-4(1H)-quinolinylidene)- Catalog No.:AG0005N5 MDL No.: MF:C14H11N3O MW:237.2566	CAS No. 10182-48-6 3,4-Pyridinediol Catalog No.:AG0005N4 MDL No.:MFCD01691806 MF:C5H5NO2 MW:111.0987	CAS No. 10182-84-0 Iodonium, diphenyl- Catalog No.:AG0005N3 MDL No.: MF:C12H10I+ MW:281.1123
CAS No. 10182-90-8 Pyridinium, 2-formyl-1-methyl- Catalog No.:AG0005N2 MDL No.: MF:C7H8NO+ MW:122.1445	CAS No. 10182-91-9 1-Dodecanaminium, N,N,N-trimethyl- Catalog No.:AG0005N1 MDL No.: MF:C15H34N+ MW:228.4372	CAS No. 101820-46-6 Glycine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-(phenylmethyl)- Catalog No.:AG0005MU MDL No.: MF:C24H30N2O5 MW:426.5054
CAS No. 101820-58-0 Imidazo[1,2-a]pyridine-3-acetic acid, 6-methyl- Catalog No.:AG0005MT MDL No.: MF:C10H10N2O2 MW:190.1986	CAS No. 101820-69-3 Imidazo[1,2-a]pyridine-3-acetic acid, ethyl ester Catalog No.:AG0005MS MDL No.:MFCD13183145 MF:C11H12N2O2 MW:204.2252	CAS No. 101821-48-1 1H-Indole, 2,6-bis(4,5-dihydro-1H-imidazol-2-yl)- Catalog No.:AG0005MR MDL No.: MF:C14H15N5 MW:253.3024
CAS No. 101822-09-7 1,3-Dioxolan-4-one, 2,2-dimethyl-5-methylene- Catalog No.:AG0005MQ MDL No.: MF:C6H8O3 MW:128.1259	CAS No. 101822-11-1 1,3-Dioxolan-4-one, 5-methylene-2-phenyl- Catalog No.:AG0005MP MDL No.: MF:C10H8O3 MW:176.1687	CAS No. 101822-26-8 Furan, 3-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethyl]-2-(trimethylsilyl)- Catalog No.:AG0005MO MDL No.: MF:C18H30OSi MW:290.5157
CAS No. 101822-35-9 3-Furanmethanol, 2-(trimethylsilyl)- Catalog No.:AG0005MN MDL No.: MF:C8H14O2Si MW:170.2811	CAS No. 101822-40-6 Cyclopentanol, 1-[2-[(1,1-dimethylethyl)sulfonyl]-2-propen-1-yl]- Catalog No.:AG0005MM MDL No.: MF:C12H22O3S MW:246.3663	CAS No. 101823-09-0 Cyclohexanol, 1-(5,6-dihydro-1,4-dioxin-2-yl)- Catalog No.:AG0005ML MDL No.: MF:C10H16O3 MW:184.2322
CAS No. 101823-10-3 Cyclopentanol, 1-(5,6-dihydro-1,4-dioxin-2-yl)- Catalog No.:AG0005MK MDL No.: MF:C9H14O3 MW:170.2057	CAS No. 101823-24-9 1,3-Decadiene, 1,1,2-trifluoro-, (3E)- Catalog No.:AG0005MJ MDL No.: MF:C10H15F3 MW:192.2213	CAS No. 101823-35-2 1-Nonene, 1,2-difluoro-1-iodo-, (1Z)- Catalog No.:AG0005MI MDL No.: MF:C9H15F2I MW:288.1167
CAS No. 101823-70-5 2-Propenoic acid, 3-(methyldiphenylsilyl)-, methyl ester, (2E)- Catalog No.:AG0005NQ MDL No.: MF:C17H18O2Si MW:282.4091	CAS No. 1018240-62-4 Benzenesulfonamide, 3-cyano-N-[(4-methoxyphenyl)methyl]- Catalog No.:AG0005NH MDL No.: MF:C15H14N2O3S MW:302.3483	CAS No. 1018243-04-3 Acetic acid, 2-(cycloheptylamino)-2-oxo- Catalog No.:AG0005NG MDL No.:MFCD10018440 MF:C9H15NO3 MW:185.2203
CAS No. 1018243-08-7 1H-Indole-1-acetic acid, 2,3-dihydro-α-oxo- Catalog No.:AG0005NF MDL No.:MFCD10018450 MF:C10H9NO3 MW:191.1834	CAS No. 101825-11-0 Benzenemethanamine, 3,4-dimethoxy-N-(1-methylethyl)- Catalog No.:AG0005NP MDL No.:MFCD01817805 MF:C12H19NO2 MW:209.2848	CAS No. 1018254-91-5 2H-1,4-Benzoxazin-3(4H)-one, 8-amino-4-methyl- Catalog No.:AG0005NE MDL No.:MFCD09998374 MF:C9H10N2O2 MW:178.1879
CAS No. 1018262-52-6 Benzenesulfonamide, 4-(2-chloroethyl)-N-(3-fluorophenyl)- Catalog No.:AG0005ND MDL No.: MF:C14H13ClFNO2S MW:313.7749	CAS No. 101827-46-7 1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1) Catalog No.:AG0005NO MDL No.:MFCD00917064 MF:C23H28ClN MW:353.9281	CAS No. 101828-21-1 1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl- Catalog No.:AG0005NN MDL No.:MFCD00865577 MF:C23H27N MW:317.4672
CAS No. 1018284-46-2 Benzenepropanamide, 4-amino-N,N-dimethyl- Catalog No.:AG0005NC MDL No.:MFCD10022146 MF:C11H16N2O MW:192.2575	CAS No. 1018285-68-1 Piperidine, 4-[(ethylsulfonyl)methyl]- Catalog No.:AG0005NB MDL No.:MFCD26792997 MF:C8H17NO2S MW:191.2911	CAS No. 1018289-07-0 1,2-Propanediamine, N2-ethyl-N2,2-dimethyl- Catalog No.:AG0005NA MDL No.:MFCD10026603 MF:C7H18N2 MW:130.2312
CAS No. 101829-66-7 Benzene, 1-[(6-bromohexyl)oxy]-4-ethenyl- Catalog No.:AG0005NM MDL No.: MF:C14H19BrO MW:283.2041	CAS No. 101829-74-7 Propanedioic acid, 2-(4-pyridinylmethyl)-, 1,3-diethyl ester Catalog No.:AG0005NL MDL No.: MF:C13H17NO4 MW:251.2784	CAS No. 1018293-21-4 4H-Pyrido[3,2-b]-1,4-oxazine-4-acetic acid, 2,3-dihydro-3-oxo- Catalog No.:AG0005N9 MDL No.:MFCD10010797 MF:C9H8N2O4 MW:208.1708
CAS No. 1018295-36-7 1H-Indole-1-acetic acid, 2,3-dihydro-2-methyl-α-oxo- Catalog No.:AG0005N8 MDL No.:MFCD10018504 MF:C11H11NO3 MW:205.2099	CAS No. 1018297-63-6 4-Isoxazolemethanol, 3-(4-fluorophenyl)-5-methyl- Catalog No.:AG0005N7 MDL No.:MFCD10008830 MF:C11H10FNO2 MW:207.2010	CAS No. 10183-38-7 L-Proline, L-leucylglycyl- Catalog No.:AG0005NV MDL No.: MF:C13H23N3O4 MW:285.3394
CAS No. 10183-41-2 2,5-Piperazinedione, 3,6-dibutyl- Catalog No.:AG0005NU MDL No.: MF:C12H22N2O2 MW:226.3153	CAS No. 10183-45-6 Androst-4-en-3-one, 16-fluoro-17-(1-oxopropoxy)-, (16β,17β)- (9CI) Catalog No.:AG0005NT MDL No.: MF:C22H31FO3 MW:362.4781	CAS No. 10183-49-0 1,4,9,10-Anthracenetetrol, 6,7-dichloro- Catalog No.:AG0005NS MDL No.: MF:C14H8Cl2O4 MW:311.1169
CAS No. 10183-94-5 1(2H)-Anthracenone, 3,4-dihydro-8,9-dihydroxy- Catalog No.:AG0005NR MDL No.: MF:C14H12O3 MW:228.2433	CAS No. 101830-33-5 Borane, [(1E)-2-(chlorodimethylstannyl)-1-ethyl-1-propen-1-yl]diethyl- Catalog No.:AG0005NK MDL No.: MF:C11H24BClSn MW:321.2733	CAS No. 101830-82-4 3-Quinolinecarboxylic acid, 6,8-difluoro-1,4-dihydro-4-oxo- Catalog No.:AG0005NJ MDL No.: MF:C10H5F2NO3 MW:225.1484
CAS No. 101830-83-5 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo- Catalog No.:AG0005NI MDL No.: MF:C12H9F2NO3 MW:253.2016	CAS No. 101830-94-8 2-Propenamide, 2-methyl-N-2-thiazolyl- Catalog No.:AG0005OK MDL No.:MFCD00458154 MF:C7H8N2OS MW:168.2162	CAS No. 1018300-38-3 β-Alanine, N-[[[(4-chlorophenyl)methyl]amino]carbonyl]- Catalog No.:AG0005NY MDL No.: MF:C11H13ClN2O3 MW:256.6855
CAS No. 101831-36-1 Benzeneacetonitrile, 2-chloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)- Catalog No.:AG0005OJ MDL No.: MF:C17H10Cl2N4O2 MW:373.1929	CAS No. 101831-37-2 Benzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)- Catalog No.:AG0005OI MDL No.:MFCD00867203 MF:C17H9Cl3N4O2 MW:407.6380	CAS No. 101831-38-3 Morpholine, 4-[(1-phenylcyclohexyl)methyl]- Catalog No.:AG0005OH MDL No.: MF:C17H25NO MW:259.3865
CAS No. 101831-42-9 1-Tridecanone, 1-(4-morpholinyl)- Catalog No.:AG0005OG MDL No.: MF:C17H33NO2 MW:283.4494	CAS No. 101831-70-3 Dodecanoic acid, 2-methoxy-4-[[(1-oxododecyl)amino]methyl]phenyl ester Catalog No.:AG0005OF MDL No.: MF:C32H55NO4 MW:517.7834	CAS No. 101831-71-4 1H-Indole-5-carbonitrile, 3-(2-aminoethyl)-, hydrochloride (1:1) Catalog No.:AG0005OE MDL No.:MFCD01719136 MF:C11H12ClN3 MW:221.6861
CAS No. 101832-10-4 Ethanone, 2,2,2-trifluoro-1-(5-nitro-1H-indol-3-yl)- Catalog No.:AG0005OD MDL No.:MFCD01718619 MF:C10H5F3N2O3 MW:258.1535	CAS No. 101832-14-8 Nonanamide, N-[(4-chlorophenyl)methyl]- Catalog No.:AG0005OC MDL No.: MF:C16H24ClNO MW:281.8209	CAS No. 101832-19-3 Nonanamide, N-[(4-methoxyphenyl)methyl]- Catalog No.:AG0005OB MDL No.: MF:C17H27NO2 MW:277.4018
CAS No. 101832-25-1 Nonanimidic acid, N-methoxy-, methyl ester Catalog No.:AG0005OA MDL No.: MF:C11H23NO2 MW:201.3058	CAS No. 101832-26-2 Cyclobutanenonanoic acid, 2,2,3,3-tetrafluoro- Catalog No.:AG0005O9 MDL No.: MF:C13H20F4O2 MW:284.2903	CAS No. 101832-55-7 Bicyclo[2.2.1]hept-5-ene-2,3-diacetonitrile Catalog No.:AG0005O8 MDL No.: MF:C11H12N2 MW:172.2264
CAS No. 101832-73-9 1H-Indol-7-amine, 2,3-dimethyl- Catalog No.:AG0005O7 MDL No.:MFCD01719234 MF:C10H12N2 MW:160.2157	CAS No. 101833-01-6 D-Fructose, 1,3,4,5,6-pentaacetate, compd. with (2,4-dinitrophenyl)hydrazine (1:1) (9CI) Catalog No.:AG0005O5 MDL No.: MF: MW:	CAS No. 101833-02-7 3-Furancarboxamide, 5-nitro-N-(tetrahydro-5,5-dimethyl-2-oxo-3-furanyl)- Catalog No.:AG0005O4 MDL No.: MF:C11H12N2O6 MW:268.2228
CAS No. 101833-08-3 2(5H)-Furanone, 4-(chloromethyl)-3-phenyl- Catalog No.:AG0005O3 MDL No.: MF:C11H9ClO2 MW:208.6410	CAS No. 101833-09-4 2(3H)-Furanone, dihydro-5-methyl-3-phenyl-3-(2-propen-1-yl)- Catalog No.:AG0005O2 MDL No.: MF:C14H16O2 MW:216.2756	CAS No. 101833-11-8 3(2H)-Furanone, dihydro-2-hydroxy-2-methyl-5,5-bis(trifluoromethyl)- Catalog No.:AG0005O1 MDL No.: MF:C7H6F6O3 MW:252.1112
CAS No. 101833-14-1 3(2H)-Furanone, dihydro-5,5-bis(trifluoromethyl)-, oxime Catalog No.:AG0005O0 MDL No.: MF:C6H5F6NO2 MW:237.0998	CAS No. 101833-22-1 β-D-Galactopyranoside, ethyl 4,6-O-(phenylmethylene)- Catalog No.:AG0005NZ MDL No.: MF:C15H20O6 MW:296.3157	CAS No. 1018334-04-7 Piperidine, 1-[[4-(2-chloroethyl)phenyl]sulfonyl]- Catalog No.:AG0005NX MDL No.: MF:C13H18ClNO2S MW:287.8055
CAS No. 1018334-05-8 Benzenesulfonamide, 4-(2-chloroethyl)-N-(2-methoxyethyl)- Catalog No.:AG0005NW MDL No.: MF:C11H16ClNO3S MW:277.7676	CAS No. 1018337-05-7 1-Piperidineacetonitrile, 4-oxo-α-phenyl- Catalog No.:AG0005OO MDL No.:MFCD10014840 MF:C13H14N2O MW:214.2631	CAS No. 1018339-50-8 Benzenesulfonamide, 4-(2-chloroethyl)-N-(1-methylpropyl)- Catalog No.:AG0005ON MDL No.: MF:C12H18ClNO2S MW:275.7948
CAS No. 101834-69-9 Vanadium, bis[(1,2,3,3a,7a-η)-1H-inden-1-yl]- Catalog No.:AG0005P0 MDL No.: MF:C18H14V MW:281.2453	CAS No. 101834-90-6 Acetic acid, 2-bromo-2-chloro-2-(diethoxyphosphinyl)-, ethyl ester Catalog No.:AG0005OZ MDL No.: MF:C8H15BrClO5P MW:337.5325	CAS No. 1018340-07-2 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-[(phenylmethyl)amino]-, (3R,4R)-rel- Catalog No.:AG0005OM MDL No.: MF:C22H21NO4 MW:363.4064
CAS No. 101835-17-0 2-Oxazolidinone, 5-ethyl-3-phenyl- Catalog No.:AG0005OY MDL No.: MF:C11H13NO2 MW:191.2264	CAS No. 101836-84-4 Gallium, [bis(2,4,6-trimethylphenyl)arsino]dichloro- (9CI) Catalog No.:AG0005OX MDL No.: MF:C18H22AsCl2Ga MW:453.9179	CAS No. 101836-98-0 1-Octadecanamine, N-(1,3-dimethylbutylidene)- Catalog No.:AG0005OW MDL No.: MF:C24H49N MW:351.6526
CAS No. 101838-56-6 Phosphonium, [2-oxo-2-(phenylamino)ethyl]triphenyl-, chloride (1:1) Catalog No.:AG0005OV MDL No.: MF:C26H23ClNOP MW:431.8937	CAS No. 10184-00-6 Formamide, N-(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)- Catalog No.:AG0005P9 MDL No.: MF:C5H6N4O3 MW:170.1261	CAS No. 10184-01-7 Acetamide, N-(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)- Catalog No.:AG0005P8 MDL No.: MF:C6H8N4O3 MW:184.1527
CAS No. 10184-19-7 3H-Purin-6-amine, 3-(diphenylmethyl)- Catalog No.:AG0005P7 MDL No.: MF:C18H15N5 MW:301.3452	CAS No. 10184-20-0 9H-Purin-6-amine, N-(diphenylmethyl)-, hydrochloride (1:1) Catalog No.:AG0005P6 MDL No.: MF:C18H16ClN5 MW:337.8061	CAS No. 10184-51-7 9H-Purin-6-amine, 9-methyl-, 1-oxide Catalog No.:AG0005P5 MDL No.: MF:C6H7N5O MW:165.1527
CAS No. 10184-66-4 Phosphonic acid, P-(1-hydroxyethyl)-, dimethyl ester Catalog No.:AG0005P4 MDL No.: MF:C4H11O4P MW:154.1015	CAS No. 10184-68-6 Phosphonic acid, (1-hydroxy-1-methylethyl)-, dimethyl ester (6CI,7CI,8CI,9CI) Catalog No.:AG0005P3 MDL No.: MF:C5H13O4P MW:168.1281	CAS No. 10184-96-0 Propanedioic acid, 2-(1H-indol-3-ylmethylene)-, 1,3-diethyl ester Catalog No.:AG0005P2 MDL No.:MFCD00022744 MF:C16H17NO4 MW:287.3105
CAS No. 10184-98-2 Propanedioic acid, 2-(1H-indol-3-ylmethyl)-, 1,3-diethyl ester Catalog No.:AG0005P1 MDL No.: MF:C16H19NO4 MW:289.3264	CAS No. 101842-77-7 9,12-Octadecadienoic acid (9Z,12Z)-, 1-hexyl-12-(isohexadecyloxy)-12-oxododecyl ester (9CI) Catalog No.:AG0005OU MDL No.: MF:C52H98O4 MW:787.3321	CAS No. 101843-14-5 Anthracenone Catalog No.:AG0005OT MDL No.: MF:C14H10O MW:194.2286
CAS No. 101843-38-3 Dodecanoic acid, 1-(sulfophenyl) ester Catalog No.:AG0005OS MDL No.: MF:C18H28O5S MW:356.4769	CAS No. 101843-39-4 Benzene, tetramethoxy(2-propen-1-yl)- Catalog No.:AG0005OR MDL No.:MFCD10037571 MF:C13H18O4 MW:238.2796	CAS No. 101843-94-1 1H-1,2,4-Triazole-3-carboxamide, 1-(2,3,5-tri-O-butyl-β-D-ribofuranosyl)- Catalog No.:AG0005OQ MDL No.: MF:C20H36N4O5 MW:412.5236
CAS No. 1018437-11-0 1-Piperidineacetonitrile, 4-hydroxy-α-phenyl- Catalog No.:AG0005OL MDL No.:MFCD10014842 MF:C13H16N2O MW:216.2789	CAS No. 101844-21-7 2-Propen-1-ol, 3-(dimethylphenylsilyl)-, (2E)- Catalog No.:AG0005OP MDL No.: MF:C11H16OSi MW:192.3296	CAS No. 101844-22-8 2-Propen-1-ol, 2-(dimethylphenylsilyl)- Catalog No.:AG0005PT MDL No.: MF:C11H16OSi MW:192.3296
CAS No. 1018441-16-1 1H-Pyrrolo[2,3-b]pyridin-6-amine, N-methyl- Catalog No.:AG0005PK MDL No.:MFCD09910035 MF:C8H9N3 MW:147.1772	CAS No. 1018443-00-9 Pyrrolidine, 3-(1-azetidinyl)-, hydrochloride (1:1) Catalog No.:AG0005PJ MDL No.: MF:C7H15ClN2 MW:162.6604	CAS No. 1018443-01-0 Carbamic acid, N-(3-methyl-3-azetidinyl)-, 1,1-dimethylethyl ester Catalog No.:AG0005PI MDL No.:MFCD11974378 MF:C9H18N2O2 MW:186.2514
CAS No. 1018443-32-7 Pyrrolo[3,4-b]pyrrole-1(2H)-carboxylic acid, hexahydro-, 1,1-dimethylethyl ester, (3aR,6aR)-rel- Catalog No.:AG0005PH MDL No.:MFCD18917061 MF:C11H20N2O2 MW:212.2887	CAS No. 1018446-60-0 1H-Pyrazole-3-carboxylic acid, 5-hydroxy-, methyl ester Catalog No.:AG0005PG MDL No.:MFCD09878841 MF:C5H6N2O3 MW:142.1127	CAS No. 1018446-95-1 1H-Pyrazole-1-carboxylic acid, 4-amino-, 1,1-dimethylethyl ester Catalog No.:AG0005PF MDL No.:MFCD20697038 MF:C8H13N3O2 MW:183.2077
CAS No. 1018450-37-7 Benzenamine, 4-chloro-3-fluoro-2-iodo- Catalog No.:AG0005PE MDL No.:MFCD18250658 MF:C6H4ClFIN MW:271.4585	CAS No. 1018453-54-7 2-Piperidinone, 6-ethyl-, (6R)- Catalog No.:AG0005PD MDL No.: MF:C7H13NO MW:127.1842	CAS No. 101846-83-7 1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]- Catalog No.:AG0005PS MDL No.: MF:C22H25N MW:303.4406
CAS No. 1018473-22-7 1H-Pyrazol-5-amine, 1-(6-chloro-4-pyrimidinyl)-3-methyl- Catalog No.:AG0005PC MDL No.:MFCD19440630 MF:C8H8ClN5 MW:209.6356	CAS No. 1018473-31-8 1,3-Benzenediamine, 4-methyl-N3-[3-methyl-1-[6-(methylamino)-4-pyrimidinyl]-1H-pyrazol-5-yl]- Catalog No.:AG0005PB MDL No.: MF:C16H19N7 MW:309.3690	CAS No. 1018478-41-5 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[[(2S)-3-methoxy-2-methylpropoxy]methyl]phenyl]-5-[(triphenylmethoxy)methyl]-, phenylmethyl ester, (3R,4R,5S)- Catalog No.:AG0005PA MDL No.: MF:C45H49NO6 MW:699.8737
CAS No. 101848-19-5 Carbamic acid, [5-(methylthio)-1,2,4-thiadiazol-3-yl]-, methyl ester (9CI) Catalog No.:AG0005PR MDL No.:MFCD00846949 MF:C5H7N3O2S2 MW:205.2580	CAS No. 101848-25-3 L-Threonine, L-isoleucyl-L-threonyl- Catalog No.:AG0005PQ MDL No.: MF:C14H27N3O6 MW:333.3807	CAS No. 101848-26-4 Glycine, N-[N-[N-[N-[N-[N-(N-L-leucyl-L-phenylalanyl)-L-valyl]-L-valyl]-L-threonyl]-L-leucyl]-L-valyl]- (9CI) Catalog No.:AG0005PP MDL No.: MF:C42H70N8O10 MW:847.0528
CAS No. 101848-68-4 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-, mixt. with 1-(2,4-dichlorophenyl)-2-(3-pyridinyl)ethanone O-methyloxime (9CI) Catalog No.:AG0005PO MDL No.: MF: MW:	CAS No. 101849-21-2 1,1,3,3-Propanetetrol, 2-heptyl- Catalog No.:AG0005PN MDL No.: MF:C10H22O4 MW:206.2793	CAS No. 101849-67-6 Stannane, [(1Z)-1-(2-chloroethyl)-1-propen-1-yl]trimethyl- Catalog No.:AG0005PM MDL No.: MF:C8H17ClSn MW:267.3746
CAS No. 101849-78-9 2H-Cyclopenta[b]furan-2-one, hexahydro-4-[(1E,3S,5S)-5-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-1-nonen-1-yl]-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4R,5R,6aS)- Catalog No.:AG0005PL MDL No.:MFCD23115482 MF:C27H44O6 MW:464.6347	CAS No. 10185-00-9 2H-1-Benzopyran-3-carboxamide Catalog No.:AG0005PY MDL No.: MF:C10H9NO2 MW:175.1840	CAS No. 10185-29-2 2,5-Pyrrolidinedione, 3-(1H-indol-3-yl)- Catalog No.:AG0005PX MDL No.:MFCD03192751 MF:C12H10N2O2 MW:214.2200
CAS No. 10185-45-2 9H-Carbazole-9-ethanol, 3-nitro- Catalog No.:AG0005PW MDL No.: MF:C14H12N2O3 MW:256.2567	CAS No. 10185-46-3 2H-1-Benzopyran-3-methanamine, 3,4-dihydro- Catalog No.:AG0005PV MDL No.:MFCD04114627 MF:C10H13NO MW:163.2163	CAS No. 10185-62-3 Benzenesulfonyl chloride, 3-(5-methyl-1,2,4-oxadiazol-3-yl)- Catalog No.:AG0005PU MDL No.:MFCD06797486 MF:C9H7ClN2O3S MW:258.6815
CAS No. 10185-65-6 1,2,4-Oxadiazole, 5-ethyl-3-(4-nitrophenyl)- Catalog No.:AG0005QN MDL No.:MFCD09972166 MF:C10H9N3O3 MW:219.1968	CAS No. 10185-66-7 1,2,4-Oxadiazole, 5-butyl-3-(3-nitrophenyl)- Catalog No.:AG0005QM MDL No.:MFCD10699664 MF:C12H13N3O3 MW:247.2499	CAS No. 10185-68-9 Benzenamine, 4-(5-methyl-1,2,4-oxadiazol-3-yl)- Catalog No.:AG0005QL MDL No.:MFCD08435856 MF:C9H9N3O MW:175.1873
CAS No. 10185-69-0 Benzenamine, 3-(5-methyl-1,2,4-oxadiazol-3-yl)- Catalog No.:AG0005QK MDL No.:MFCD08443707 MF:C9H9N3O MW:175.1873	CAS No. 10185-71-4 Benzenamine, 4-(5-ethyl-1,2,4-oxadiazol-3-yl)- Catalog No.:AG0005QJ MDL No.: MF:C10H11N3O MW:189.2138	CAS No. 101850-43-5 Pyrimido[5,4-d]pyrimidin-4-amine, 2,8-dichloro-N,N-diethyl- Catalog No.:AG0005QI MDL No.: MF:C10H11Cl2N5 MW:272.1338
CAS No. 101850-71-9 1H-Pyrazol-5-amine, 4-(1H-1,2,4-triazol-1-yl)-1-(2,4,6-trichlorophenyl)- Catalog No.:AG0005QH MDL No.: MF:C11H7Cl3N6 MW:329.5725	CAS No. 1018502-06-1 Benzamide, 3-amino-4-chloro-N-(3-pyridinylmethyl)- Catalog No.:AG0005Q4 MDL No.:MFCD10021697 MF:C13H12ClN3O MW:261.7069	CAS No. 1018505-59-3 2-Pyridinamine, 5-(4-ethyl-1-piperazinyl)- Catalog No.:AG0005Q3 MDL No.:MFCD10009575 MF:C11H18N4 MW:206.2874
CAS No. 1018506-33-6 Benzenepropanamide, 2-amino-N,N-dimethyl- Catalog No.:AG0005Q2 MDL No.:MFCD10022148 MF:C11H16N2O MW:192.2575	CAS No. 101851-40-5 Hydrazine, (4-chloro-1-naphthalenyl)- Catalog No.:AG0005QG MDL No.:MFCD06738784 MF:C10H9ClN2 MW:192.6449	CAS No. 101853-07-0 Methanone, bis[4-(dibutylamino)phenyl]- Catalog No.:AG0005QF MDL No.: MF:C29H44N2O MW:436.6725
CAS No. 101853-22-9 Silacyclohepta-2,4,6-triene Catalog No.:AG0005QE MDL No.: MF:C6H8Si MW:108.2132	CAS No. 101853-43-4 Benzoic acid, 2-hydroxy-, cyclohexylmethyl ester Catalog No.:AG0005QD MDL No.: MF:C14H18O3 MW:234.2909	CAS No. 101853-47-8 Decanoic acid,5-hydroxy-, methyl ester Catalog No.:AG0005QC MDL No.: MF:C11H22O3 MW:202.2906
CAS No. 101853-49-0 Octanoic acid, 5-hydroxy-, methyl ester Catalog No.:AG0005QB MDL No.: MF:C9H18O3 MW:174.2374	CAS No. 101853-53-6 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3,3-dimethyloctyl)-5-ethyl- Catalog No.:AG0005QA MDL No.: MF:C16H28N2O3 MW:296.4051	CAS No. 101853-75-2 1H-Imidazole, 2,4,5-tribromo-1-[(3,4-dimethoxyphenyl)methyl]- Catalog No.:AG0005Q9 MDL No.: MF:C12H11Br3N2O2 MW:454.9399
CAS No. 101853-76-3 1H-Imidazole, 4,5-dibromo-1-(methoxymethyl)- Catalog No.:AG0005Q8 MDL No.: MF:C5H6Br2N2O MW:269.9219	CAS No. 101853-81-0 1H-Imidazole, 4,5-dibromo-2-(ethylthio)-1-(methoxymethyl)- Catalog No.:AG0005Q7 MDL No.: MF:C7H10Br2N2OS MW:330.0401	CAS No. 101853-86-5 1H-Imidazole, 4,5-dibromo-1-(phenylmethyl)-2-(phenylthio)- Catalog No.:AG0005Q6 MDL No.: MF:C16H12Br2N2S MW:424.1529
CAS No. 101853-88-7 1H-Imidazole-5-carboxaldehyde, 4-bromo-1-[(4-methoxyphenyl)methyl]- Catalog No.:AG0005Q5 MDL No.: MF:C12H11BrN2O2 MW:295.1319	CAS No. 1018533-19-1 Piperidine, 4-[[(1-methylethyl)sulfonyl]methyl]- Catalog No.:AG0005Q1 MDL No.:MFCD23703555 MF:C9H19NO2S MW:205.3177	CAS No. 1018537-04-6 Benzenesulfonamide, 4-(2-chloroethyl)-N-propyl- Catalog No.:AG0005Q0 MDL No.: MF:C11H16ClNO2S MW:261.7682
CAS No. 1018537-08-0 Benzenesulfonamide, N-butyl-4-(2-chloroethyl)- Catalog No.:AG0005PZ MDL No.: MF:C12H18ClNO2S MW:275.7948	CAS No. 1018537-12-6 Benzenesulfonamide, 4-(2-chloroethyl)-N-cyclopentyl- Catalog No.:AG0005QY MDL No.:MFCD10020933 MF:C13H18ClNO2S MW:287.8055	CAS No. 1018537-40-0 Benzenesulfonamide, 4-(2-chloroethyl)-N,N-diethyl- Catalog No.:AG0005QX MDL No.: MF:C12H18ClNO2S MW:275.7948
CAS No. 1018537-56-8 1H-Indole, 1-[[4-(2-chloroethyl)phenyl]sulfonyl]-2,3-dihydro- Catalog No.:AG0005QW MDL No.: MF:C16H16ClNO2S MW:321.8217	CAS No. 1018537-64-8 Benzenesulfonamide, 4-(2-chloroethyl)-N-(2-ethylphenyl)- Catalog No.:AG0005QV MDL No.: MF:C16H18ClNO2S MW:323.8376	CAS No. 101854-08-4 1,3-Dioxolane, 2-methyl-2,4-diphenyl- Catalog No.:AG0005RC MDL No.: MF:C16H16O2 MW:240.2970
CAS No. 101854-25-5 L-Proline, 1-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl]-L-valyl]- (9CI) Catalog No.:AG0005RB MDL No.: MF:C24H35N3O6 MW:461.5512	CAS No. 101854-42-6 Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-[[(phenylmethoxy)carbonyl]amino]-, (R)-, compd. with N-cyclohexylcyclohexanamine (1:1) (9CI) Catalog No.:AG0005RA MDL No.:MFCD00798628 MF:C29H47N3O6 MW:533.7000	CAS No. 101854-80-2 Pyrimidine, 1,4-dihydro-2-methyl- Catalog No.:AG0005R9 MDL No.: MF:C5H8N2 MW:96.1304
CAS No. 1018544-60-9 1-Piperazinecarboxylic acid, 4-[2-amino-1-(4-bromophenyl)ethyl]-, 1,1-dimethylethyl ester Catalog No.:AG0005QU MDL No.: MF:C17H26BrN3O2 MW:384.3112	CAS No. 1018548-98-5 β-Alanine, N-[[(2-phenylethyl)amino]carbonyl]- Catalog No.:AG0005QT MDL No.: MF:C12H16N2O3 MW:236.2670	CAS No. 1018549-00-2 2H-Indol-2-one, 1,3-dihydro-3-(hydroxymethylene)-5-methoxy- Catalog No.:AG0005QS MDL No.: MF:C10H9NO3 MW:191.1834
CAS No. 101855-18-9 4H-Naphth[1,2-d][1,3]oxazin-4-one, 2-methyl- Catalog No.:AG0005R8 MDL No.: MF:C13H9NO2 MW:211.2161	CAS No. 101855-37-2 2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-, 1-methylethyl ester Catalog No.:AG0005R7 MDL No.: MF:C13H13NO4 MW:247.2466	CAS No. 101855-91-8 Methanone, bis[2-chloro-5-(trifluoromethyl)phenyl]- Catalog No.:AG0005R6 MDL No.: MF:C15H6Cl2F6O MW:387.1040
CAS No. 1018555-33-3 1-Propanone, 1-[4-(aminomethyl)-1-piperidinyl]-2,2-dimethyl- Catalog No.:AG0005QR MDL No.: MF:C11H22N2O MW:198.3052	CAS No. 1018557-32-8 Piperidine, 4-[(propylsulfonyl)methyl]- Catalog No.:AG0005QQ MDL No.:MFCD10017396 MF:C9H19NO2S MW:205.3177	CAS No. 1018564-07-2 Benzamide, 4-amino-3-methyl-N-(3-pyridinylmethyl)- Catalog No.:AG0005QP MDL No.:MFCD10022000 MF:C14H15N3O MW:241.2884
CAS No. 1018565-99-5 1(2H)-Quinolineacetic acid, 3,4-dihydro-α-oxo- Catalog No.:AG0005QO MDL No.:MFCD10018451 MF:C11H11NO3 MW:205.2099	CAS No. 101857-31-2 1,2,5-Selenadiazole-3-carbonyl chloride Catalog No.:AG0005R5 MDL No.: MF:C3HClN2OSe MW:195.4658	CAS No. 101857-33-4 1,2-Propanediamine, 3-[(tetrahydro-2H-pyran-2-yl)oxy]- Catalog No.:AG0005R4 MDL No.: MF:C8H18N2O2 MW:174.2407
CAS No. 101857-37-8 1,2-Propanediamine, 3-methoxy- Catalog No.:AG0005R3 MDL No.:MFCD19204176 MF:C4H12N2O MW:104.1509	CAS No. 101857-61-8 1,2-Oxathiin, 3-bromo-4-(bromomethyl)-6-methyl-, 2,2-dioxide Catalog No.:AG0005R2 MDL No.: MF:C6H6Br2O3S MW:317.9830	CAS No. 101858-16-6 Hydrazinecarboxamide, N-[3-(diethylamino)propyl]-2-[(5-nitro-2-furanyl)methylene]- Catalog No.:AG0005R1 MDL No.: MF:C13H21N5O4 MW:311.3369
CAS No. 101858-22-4 8-Azabicyclo[3.2.1]octane-8-butanol, 3-hydroxy-α,α,3-triphenyl- Catalog No.:AG0005R0 MDL No.: MF:C29H33NO2 MW:427.5778	CAS No. 101858-24-6 8-Azabicyclo[3.2.1]octan-3-ol, 3-phenyl-8-(2-phenylethyl)- Catalog No.:AG0005QZ MDL No.: MF:C21H25NO MW:307.4293	CAS No. 101858-27-9 9-Octadecenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- Catalog No.:AG0005RU MDL No.: MF:C26H43NO3 MW:417.6245
CAS No. 101858-33-7 Octanimidic acid, N-methoxy-, methyl ester Catalog No.:AG0005RT MDL No.:MFCD01711119 MF:C10H21NO2 MW:187.2792	CAS No. 101859-28-3 2-Butenoic acid, 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexyl]-, methyl ester, [1α(Z),2β]- (9CI) Catalog No.:AG0005RS MDL No.: MF:C17H32O3Si MW:312.5197	CAS No. 101859-37-4 2-Pentenoic acid, 5-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexyl]-, methyl ester, [1α(Z),2β]- (9CI) Catalog No.:AG0005RR MDL No.: MF:C18H34O3Si MW:326.5463
CAS No. 101859-47-6 2-Pentenoic acid, 5-[2-[(4-bromophenyl)methoxy]cyclohexyl]-, methyl ester, [1α(Z),2β]- (9CI) Catalog No.:AG0005RQ MDL No.: MF:C19H25BrO3 MW:381.3040	CAS No. 101859-54-5 2-Pentenoic acid, 5-[2-[bis(4-chlorophenyl)methoxy]cyclohexyl]-, methyl ester, [1α(Z),2β]- (9CI) Catalog No.:AG0005RP MDL No.: MF:C25H28Cl2O3 MW:447.3940	CAS No. 101859-91-0 Hydrazine, 5-hexen-1-yl- Catalog No.:AG0005RO MDL No.: MF:C6H14N2 MW:114.1888
CAS No. 10186-22-8 2H-Pyran-2-one, tetrahydro-6-(2-phenylethyl)- Catalog No.:AG0005S1 MDL No.: MF:C13H16O2 MW:204.2649	CAS No. 10186-26-2 Butanedioic acid, 2,2-diphenyl- Catalog No.:AG0005S0 MDL No.: MF:C16H14O4 MW:270.2800	CAS No. 10186-63-7 Propanoic acid, 2,3,3,3-tetrafluoro-2-methoxy-, methyl ester Catalog No.:AG0005RZ MDL No.:MFCD00155951 MF:C5H6F4O3 MW:190.0930
CAS No. 10186-64-8 Propanoic acid, 2,3,3,3-tetrafluoro-2-methoxy- Catalog No.:AG0005RY MDL No.:MFCD20638862 MF:C4H4F4O3 MW:176.0664	CAS No. 10186-65-9 Propanamide, 2,3,3,3-tetrafluoro-2-methoxy- Catalog No.:AG0005RX MDL No.:MFCD00193112 MF:C4H5F4NO2 MW:175.0816	CAS No. 10186-66-0 Propanoic acid, 2-ethoxy-2,3,3,3-tetrafluoro-, ethyl ester Catalog No.:AG0005RW MDL No.:MFCD00205158 MF:C7H10F4O3 MW:218.1461
CAS No. 10186-73-9 Propanoic acid, 2-bromo-2,3,3,3-tetrafluoro-, ethyl ester Catalog No.:AG0005RV MDL No.:MFCD00153721 MF:C5H5BrF4O2 MW:252.9896	CAS No. 101860-03-1 12,14-Nonacosadiynoic acid Catalog No.:AG0005RN MDL No.: MF:C29H50O2 MW:430.7061	CAS No. 101860-05-3 Arsine, bis[(trimethylsilyl)methyl]- Catalog No.:AG0005RM MDL No.: MF:C8H23AsSi2 MW:250.3608
CAS No. 101860-51-9 2-Thiazolidinone, 4-acetyl-3-[(4-methoxyphenyl)methyl]-, (4R)- Catalog No.:AG0005RL MDL No.: MF:C13H15NO3S MW:265.3281	CAS No. 101860-71-3 Quinoline, 3-chloro-6-nitro- Catalog No.:AG0005RK MDL No.: MF:C9H5ClN2O2 MW:208.6012	CAS No. 101860-74-6 4H-1-Benzopyran-4-one, 7-chloro- Catalog No.:AG0005RJ MDL No.: MF:C9H5ClO2 MW:180.5878
CAS No. 101860-97-3 3-Pyridineacetic acid, 2-amino- Catalog No.:AG0005RI MDL No.:MFCD11848318 MF:C7H8N2O2 MW:152.1506	CAS No. 1018600-42-4 Benzamide, 4-(3-aminopropoxy)- Catalog No.:AG0005RD MDL No.:MFCD10037139 MF:C10H14N2O2 MW:194.2304	CAS No. 101861-00-1 5-Pyrimidinecarboxaldehyde, 1,6-dihydro-2,4-dimethyl-6-oxo- Catalog No.:AG0005RH MDL No.: MF:C7H8N2O2 MW:152.1506
CAS No. 101861-10-3 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-ethyl-1,5-dihydro- Catalog No.:AG0005RG MDL No.: MF:C7H8N4O MW:164.1646	CAS No. 101861-35-2 [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-ethyl- Catalog No.:AG0005RF MDL No.: MF:C7H8N4O MW:164.1646	CAS No. 101861-36-3 6(5H)-Pteridinone, 7,8-dihydro-7-hydroxy-5-methyl- Catalog No.:AG0005RE MDL No.: MF:C7H8N4O2 MW:180.1640
CAS No. 101861-40-9 2-Thiophenecarboxylic acid, 5-(ethylthio)- Catalog No.:AG0005SQ MDL No.:MFCD00738671 MF:C7H8O2S2 MW:188.2672	CAS No. 101861-47-6 Quinoxaline, 2-methoxy-6-nitro- Catalog No.:AG0005SP MDL No.: MF:C9H7N3O3 MW:205.1702	CAS No. 101861-53-4 Benzoic acid, 2-(acetylamino)-4-bromo- Catalog No.:AG0005SO MDL No.:MFCD12805958 MF:C9H8BrNO3 MW:258.0687
CAS No. 101861-59-0 Quinoline, 3,5-dibromo- Catalog No.:AG0005SN MDL No.: MF:C9H5Br2N MW:286.9507	CAS No. 101861-61-4 4-Quinolinol, 6-chloro-3-nitro- Catalog No.:AG0005SM MDL No.:MFCD09800425 MF:C9H5ClN2O3 MW:224.6006	CAS No. 101861-63-6 1H-Indole-2-carboxylic acid, 4,6-dichloro- Catalog No.:AG0005SL MDL No.:MFCD00209870 MF:C9H5Cl2NO2 MW:230.0475
CAS No. 1018610-80-4 Piperazine, 2-(4-methoxyphenyl)-1-methyl- Catalog No.:AG0005SJ MDL No.: MF:C12H18N2O MW:206.2841	CAS No. 1018612-26-4 2-Propenoic acid, 3-(4-bromo-1H-indol-3-yl)- Catalog No.:AG0005SI MDL No.: MF:C11H8BrNO2 MW:266.0907	CAS No. 1018614-94-2 Benzeneacetic acid, α,α-dimethyl-4-(4-morpholinyl)- Catalog No.:AG0005SH MDL No.: MF:C14H19NO3 MW:249.3056
CAS No. 1018616-74-4 Quinoline, 2-chloro-8-methyl-3-phenyl- Catalog No.:AG0005SG MDL No.: MF:C16H12ClN MW:253.7262	CAS No. 101862-42-4 5-Isoxazolemethanol, 3-(3-chlorophenyl)- Catalog No.:AG0005SK MDL No.:MFCD19105424 MF:C10H8ClNO2 MW:209.6290	CAS No. 1018637-87-0 1H-Indole-2-ethanamine, 6-bromo- Catalog No.:AG0005SF MDL No.:MFCD10035470 MF:C10H11BrN2 MW:239.1117
CAS No. 1018656-53-5 Morpholine, 2-(2-pyridinyl)- Catalog No.:AG0005SE MDL No.:MFCD10035254 MF:C9H12N2O MW:164.2044	CAS No. 1018656-57-9 Morpholine, 2-(4-pyridinyl)- Catalog No.:AG0005SD MDL No.:MFCD10035256 MF:C9H12N2O MW:164.2044	CAS No. 1018660-79-1 Benzeneacetic acid, α,α-dimethyl-4-(1-pyrrolidinyl)- Catalog No.:AG0005SC MDL No.: MF:C14H19NO2 MW:233.3062
CAS No. 1018660-87-1 Benzeneacetic acid, α,α-dimethyl-4-(4-methyl-1-piperazinyl)- Catalog No.:AG0005SB MDL No.: MF:C15H22N2O2 MW:262.3474	CAS No. 1018662-21-9 3-Isoxazolemethanamine, 5-(4-methoxyphenyl)- Catalog No.:AG0005SA MDL No.:MFCD09864171 MF:C11H12N2O2 MW:204.2252	CAS No. 1018663-45-0 3-Cyclopentapyrazolecarboxaldehyde, 1,4,5,6-tetrahydro- Catalog No.:AG0005S9 MDL No.:MFCD10036254 MF:C7H8N2O MW:136.1512
CAS No. 1018665-73-0 Benzenepropanol, β-amino-2-methoxy- Catalog No.:AG0005S8 MDL No.: MF:C10H15NO2 MW:181.2316	CAS No. 1018667-18-9 1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-rel- Catalog No.:AG0005S7 MDL No.: MF:C11H20N2O4 MW:244.2875	CAS No. 1018678-37-9 Methyl 4-amino-2-chloronicotinate Catalog No.:AG0005S6 MDL No.:MFCD20726014 MF:C7H7ClN2O2 MW:186.5957
CAS No. 1018678-38-0 3-Pyridinecarboxylic acid, 4-amino-2-chloro- Catalog No.:AG0005S5 MDL No.:MFCD13188881 MF:C6H5ClN2O2 MW:172.5691	CAS No. 1018678-39-1 3-Pyridinecarboxylic acid, 4-chloro-2-(trifluoromethyl)- Catalog No.:AG0005S4 MDL No.:MFCD22546902 MF:C7H3ClF3NO2 MW:225.5524	CAS No. 1018678-48-2 Benzoic acid, 2-(difluoromethyl)-, methyl ester Catalog No.:AG0005S3 MDL No.:MFCD16140192 MF:C9H8F2O2 MW:186.1554
CAS No. 1018678-50-6 Benzaldehyde, 2-(difluoromethyl)- Catalog No.:AG0005S2 MDL No.:MFCD16875639 MF:C8H6F2O MW:156.1294	CAS No. 1018679-79-2 1H-Pyrazolo[3,4-g]isoquinoline, 4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-6-[[4-(trifluoromethyl)phenyl]sulfonyl]-, (4aR)- Catalog No.:AG0005SV MDL No.: MF:C26H25F4N3O3S MW:535.5536	CAS No. 101868-30-8 Benzoic acid, 3,5-dibromo-2-hydroxy-, 2-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylene]hydrazide Catalog No.:AG0005T8 MDL No.: MF:C19H16Br2N4O3 MW:508.1633
CAS No. 101868-36-4 Pyridine, 2-chloro-4,6-dimethyl-3,5-diphenyl- Catalog No.:AG0005T7 MDL No.: MF:C19H16ClN MW:293.7900	CAS No. 101868-79-5 9H-Carbazol-3-amine, N-(phenylmethyl)- Catalog No.:AG0005T6 MDL No.: MF:C19H16N2 MW:272.3437	CAS No. 1018680-09-5 Boronic acid, B-[5-(dimethylamino)-3-pyridinyl]- Catalog No.:AG0005SU MDL No.:MFCD12964565 MF:C7H11BN2O2 MW:165.9854
CAS No. 1018680-22-2 Ethanone, 1-(3-amino-1-piperidinyl)- Catalog No.:AG0005ST MDL No.:MFCD09264572 MF:C7H14N2O MW:142.1989	CAS No. 1018681-31-6 Benzene, 1-bromo-4-[(cyclopropylmethoxy)methyl]- Catalog No.:AG0005SS MDL No.:MFCD14687047 MF:C11H13BrO MW:241.1243	CAS No. 101869-74-3 Cyclohexanemethanol, 4-methoxy- Catalog No.:AG0005T5 MDL No.:MFCD26885663 MF:C8H16O2 MW:144.2114
CAS No. 101869-82-3 2-Propenoic acid, 3-(2,5-dichlorophenyl)- Catalog No.:AG0005T4 MDL No.:MFCD03002786 MF:C9H6Cl2O2 MW:217.0487	CAS No. 1018690-17-9 Benzenecarbothioic acid, 2,5-difluoro-, hydrazide, hydrochloride (1:1) Catalog No.:AG0005SR MDL No.: MF:C7H7ClF2N2S MW:224.6587	CAS No. 10187-21-0 2,5-Pyrrolidinedione, 1-(4-hydroxyphenyl)- Catalog No.:AG0005TF MDL No.:MFCD00466649 MF:C10H9NO3 MW:191.1834
CAS No. 10187-79-8 Acetamide, N-[1-methyl-3-(5-nitro-2-furanyl)-1H-1,2,4-triazol-5-yl]- Catalog No.:AG0005TE MDL No.: MF:C9H9N5O4 MW:251.1989	CAS No. 10187-80-1 Acetamide, N-[4-methyl-5-(5-nitro-2-furanyl)-4H-1,2,4-triazol-3-yl]- Catalog No.:AG0005TD MDL No.: MF:C9H9N5O4 MW:251.1989	CAS No. 10187-84-5 1H-1,2,4-Triazol-5-amine, N-methyl-3-(5-nitro-2-furanyl)- Catalog No.:AG0005TC MDL No.: MF:C7H7N5O3 MW:209.1622
CAS No. 10187-86-7 4H-1,2,4-Triazol-3-amine, 4-methyl-5-(5-nitro-2-furanyl)- Catalog No.:AG0005TB MDL No.: MF:C7H7N5O3 MW:209.1622	CAS No. 10187-89-0 1H-1,2,4-Triazol-5-amine, N-ethyl-3-(5-nitro-2-furanyl)- Catalog No.:AG0005TA MDL No.: MF:C8H9N5O3 MW:223.1888	CAS No. 10187-90-3 1H-1,2,4-Triazol-5-amine, 3-(5-nitro-2-furanyl)-N-propyl- Catalog No.:AG0005T9 MDL No.: MF:C9H11N5O3 MW:237.2153
CAS No. 101870-02-4 1,3,5-Triazine, 2,4-dichloro-6-(2-nitrophenoxy)- Catalog No.:AG0005T3 MDL No.:MFCD18025182 MF:C9H4Cl2N4O3 MW:287.0591	CAS No. 101870-10-4 1H-Indole-6-carboxylic acid, 2,3-dihydro-2,3-dioxo- Catalog No.:AG0005T2 MDL No.:MFCD17676217 MF:C9H5NO4 MW:191.1403	CAS No. 101870-22-8 Pyridine, 2-propoxy- Catalog No.:AG0005T1 MDL No.: MF:C8H11NO MW:137.1790
CAS No. 101870-58-0 8-Quinolinol, 2,5,7-trichloro- Catalog No.:AG0005T0 MDL No.:MFCD00552678 MF:C9H4Cl3NO MW:248.4932	CAS No. 101870-60-4 Quinoline, 3-bromo-2-chloro- Catalog No.:AG0005SZ MDL No.:MFCD08457743 MF:C9H5BrClN MW:242.4997	CAS No. 101870-78-4 3-Pyridinol, 6-(1-methylethyl)- Catalog No.:AG0005SY MDL No.:MFCD10000595 MF:C8H11NO MW:137.1790
CAS No. 101871-32-3 Butanoic acid, 4-(butylamino)-4-oxo-, methyl ester Catalog No.:AG0005SX MDL No.: MF:C9H17NO3 MW:187.2362	CAS No. 101871-81-2 Urea, N-phenyl-N'-2-propyn-1-yl- Catalog No.:AG0005SW MDL No.:MFCD11756585 MF:C10H10N2O MW:174.1992	CAS No. 1018828-72-2 IMidazo[1,2-a]pyridine-2-carboxylic acid, 8-(trifluoroMethyl)- Catalog No.:AG0005TG MDL No.: MF:C9H5F3N2O2 MW:230.1434