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86820-21-5 | 4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol
CAS No: 86820-21-5 Catalog No: AG004IZL MDL No:
Product Description
Catalog Number:
AG004IZL
Chemical Name:
4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol
CAS Number:
86820-21-5
Molecular Formula:
C8H10FNO3
Molecular Weight:
187.1683
IUPAC Name:
4-(2-amino-1-hydroxyethyl)-5-fluorobenzene-1,2-diol
InChI:
InChI=1S/C8H10FNO3/c9-5-2-7(12)6(11)1-4(5)8(13)3-10/h1-2,8,11-13H,3,10H2
InChI Key:
SBUQBFTXTZSRMH-UHFFFAOYSA-N
SMILES:
NCC(c1cc(O)c(cc1F)O)O
Properties
Complexity:
170
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
187.064g/mol
Formal Charge:
0
Heavy Atom Count:
13
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
187.17g/mol
Monoisotopic Mass:
187.064g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
86.7A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5
Literature
| Title | Journal |
|---|---|
| Antidepressant-like action of intracerebral 6-fluoronorepinephrine, a selective full α-adrenoceptor agonist. | The international journal of neuropsychopharmacology 20110401 |
| Marked behavioral activation from inhibitory stimulation of locus coeruleus alpha1-adrenoceptors by a full agonist. | Brain research 20090929 |
| Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. | Molecular pharmacology 20070601 |
| Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors. | The Journal of comparative neurology 20060710 |
| alpha1-Adrenergic modulation of synaptic input to Purkinje neurons in rat cerebellar brain slices. | Journal of neuroscience research 20051115 |
| Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of the rat hippocampus. | The European journal of neuroscience 20040901 |
| Gross mapping of alpha1-adrenoceptors that regulate behavioral activation in the mouse brain. | Behavioural brain research 20040709 |
| Role of epinephrine stimulation of CNS alpha1-adrenoceptors in motor activity in mice. | Synapse (New York, N.Y.) 20030701 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Inhibition by L-3,4-dihydroxyphenylalanine of hippocampal CA1 neurons with facilitation of noradrenaline and gamma-aminobutyric acid release. | European journal of pharmacology 20010302 |
| Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. | Molecular pharmacology 19941101 |
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