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2179-57-9

2179-57-9 | 1,2-Diallyldisulfane

CAS No: 2179-57-9 Catalog No: AG003PB5 MDL No:MFCD00008656

Product Description

Catalog Number:
AG003PB5
Chemical Name:
1,2-Diallyldisulfane
CAS Number:
2179-57-9
Molecular Formula:
C6H10S2
Molecular Weight:
146.2736
MDL Number:
MFCD00008656
IUPAC Name:
3-(prop-2-enyldisulfanyl)prop-1-ene
InChI:
InChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2
InChI Key:
PFRGXCVKLLPLIP-UHFFFAOYSA-N
SMILES:
C=CCSSCC=C
EC Number:
218-548-6
UNII:
5HI47O6OA7
NSC Number:
29228
FEMA Number:
2028

Properties

Complexity:
58.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
146.022g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
146.266g/mol
Monoisotopic Mass:
146.022g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
50.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  

Literature

Title Journal
International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H(2)S Levels: H(2)S Donors and H(2)S Biosynthesis Inhibitors. Pharmacological reviews 20171001
Protective effects of diallyl disulfide on carbon tetrachloride-induced hepatotoxicity through activation of Nrf2. Environmental toxicology 20150501
Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140601
Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions. Environmental toxicology 20130901
Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain. Toxicology letters 20130731
Organosulfur garlic compounds induce neovasculogenesis in human endothelial progenitor cells through a modulation of MicroRNA 221 and the PI3-K/Akt signaling pathways. Journal of agricultural and food chemistry 20130522
S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin. Leukemia research 20121201
Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1. Biochemical pharmacology 20121115
Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria. Toxicology letters 20121017
Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension. European journal of pharmacology 20120915
Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia. Toxicology and applied pharmacology 20120715
Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico approach through docking analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology 20120715
Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC). Bioorganic & medicinal chemistry 20120701
Involvement of Mcl1 in diallyl disulfide-induced G2/M cell cycle arrest in HL-60 cells. Oncology reports 20120601
Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo. Phytomedicine : international journal of phytotherapy and phytopharmacology 20120515
Studies on purification of allicin by molecular distillation. Journal of the science of food and agriculture 20120501
[Garlicin ameliorated pressure overload induced myocardial fibrosis in rats through partial inhibiting TGF-beta1 mediated Smads signal]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120501
Effects of different garlic-derived allyl sulfides on peroxidative processes and anaerobic sulfur metabolism in mouse liver. Phytotherapy research : PTR 20120301
Effect of garlic sulfur compounds on neutrophil infiltration and damage to the intestinal mucosa by endotoxin in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301
Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells. Bioorganic & medicinal chemistry 20120215
Diallyl disulfide induces MUC5B expression via ERK2 in human airway epithelial cells. Phytotherapy research : PTR 20120201
Diallyl disulfide induces Ca2+ mobilization in human colon cancer cell line SW480. Archives of toxicology 20120201
Essential oil composition and antiradical activity of the oil of Iraq plants. Natural product research 20120101
Tumor angiogenesis as a target for dietary cancer prevention. Journal of oncology 20120101
S-allyl cysteine in combination with clotrimazole downregulates Fas induced apoptotic events in erythrocytes of mice exposed to lead. Biochimica et biophysica acta 20120101
Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis. Frontiers in bioscience (Landmark edition) 20120101
Greco-arab and islamic herbal-derived anticancer modalities: from tradition to molecular mechanisms. Evidence-based complementary and alternative medicine : eCAM 20120101
A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma. PloS one 20120101
Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats. International journal of biological sciences 20120101
Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae). International journal of molecular sciences 20120101
Milk fermented by Propionibacterium freudenreichii induces apoptosis of HGT-1 human gastric cancer cells. PloS one 20120101
Glutathione homeostasis and functions: potential targets for medical interventions. Journal of amino acids 20120101
An overview of the evidence and mechanisms of herb-drug interactions. Frontiers in pharmacology 20120101
Transformation of synthetic allicin: the influence of ultrasound, microwaves, different solvents and temperatures, and the products isolation. TheScientificWorldJournal 20120101
The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxidative medicine and cellular longevity 20120101
Early determinants of obesity: genetic, epigenetic, and in utero influences. International journal of pediatrics 20120101
Control of vascular smooth muscle cell growth by connexin 43. Frontiers in physiology 20120101
The attenuation of early benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells. Nutrition and cancer 20120101
Cancer chemoprevention by targeting the epigenome. Current drug targets 20111201
Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture. Parasitology research 20111101
The chemopreventive effects of aged garlic extract against cadmium-induced toxicity. Environmental toxicology and pharmacology 20110901
Diallyl disulphide and lovastatin: effects on energy and protein utilisation in, as well as methane emission from, sheep. Archives of animal nutrition 20110801
Induction of apoptosis with diallyl disulfide in AGS gastric cancer cell line. Journal of the Korean Surgical Society 20110801
Acaricidal effect of essential oils from Lippia graveolens (Lamiales: Verbenaceae), Rosmarinus officinalis (Lamiales: Lamiaceae), and Allium sativum (Liliales: Liliaceae) against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). Journal of medical entomology 20110701
Potential beneficial effects of garlic in oncohematology. Mini reviews in medicinal chemistry 20110601
Dietary inclusion of diallyl disulfide, yucca powder, calcium fumarate, an extruded linseed product, or medium-chain fatty acids does not affect methane production in lactating dairy cows. Journal of dairy science 20110601
[Mechanism of Fas/FasL signal transduction pathway in K562 cell apoptosis induced by diallyl disulfide]. Zhongguo shi yan xue ye xue za zhi 20110601
Effect of garlic-derived allyl sulphides on morphogenesis and hydrolytic enzyme secretion in Candida albicans. Medical mycology 20110501
Delivery of the bioactive gas hydrogen sulfide during cold preservation of rat liver: effects on hepatic function in an ex vivo model. Artificial organs 20110501
Inhibition of matrix metalloproteinase activities and tightening of tight junctions by diallyl disulfide in AGS human gastric carcinoma cells. Journal of food science 20110501
Structure and function relationship study of allium organosulfur compounds on upregulating the pi class of glutathione S-transferase expression. Journal of agricultural and food chemistry 20110413
Effect of diallyl disulfide on Ca2+ movement and viability in PC3 human prostate cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20110401
[Mechanism of DADS in the bystander effect of HSV-tk/GCV suicide gene therapy system in lens epithelial cells]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110401
Modulation of histone acetylation by garlic sulfur compounds. Anti-cancer agents in medicinal chemistry 20110301
Anti-proliferation activity of synthetic ajoene analogues on cancer cell-lines. Anti-cancer agents in medicinal chemistry 20110301
Anticancer effects of garlic and garlic-derived compounds for breast cancer control. Anti-cancer agents in medicinal chemistry 20110301
Sulfur volatiles from Allium spp. affect Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), response to citrus volatiles. Bulletin of entomological research 20110201
Towards the electrochemical quantification of the strength of garlic. The Analyst 20110107
[Effects of diallyl disulfide on apoptosis of human leukemia K562 cells and expression of Fas, FasL and caspase-8]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110101
Diallyl disulfide inhibits the proliferation of HT-29 human colon cancer cells by inducing differentially expressed genes. Molecular medicine reports 20110101
Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells. BMC cancer 20110101
Drosophila models of Parkinson's disease: discovering relevant pathways and novel therapeutic strategies. Parkinson's disease 20110101
Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver. PloS one 20110101
H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S? PloS one 20110101
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clinical and experimental gastroenterology 20110101
Haptenation: chemical reactivity and protein binding. Journal of allergy 20110101
Garlic Oil Alleviates MAPKs- and IL-6-mediated Diabetes-related Cardiac Hypertrophy in STZ-induced DM Rats. Evidence-based complementary and alternative medicine : eCAM 20110101
Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats. Journal of nutrition and metabolism 20110101
Diallyl disulphide, a beneficial component of garlic oil, causes a redistribution of cell-cycle growth phases, induces apoptosis, and enhances butyrate-induced apoptosis in colorectal adenocarcinoma cells (HT-29). Nutrition and cancer 20110101
Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals. PloS one 20110101
Therapeutic applications of organosulfur compounds as novel hydrogen sulfide donors and/or mediators. Expert review of clinical pharmacology 20110101
Fascioliasis control: in vivo and in vitro phytotherapy of vector snail to kill fasciola larva. Journal of parasitology research 20110101
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clinical epigenetics 20110101
Modeling natural anti-inflammatory compounds by molecular topology. International journal of molecular sciences 20110101
Role of Ras-related C3 botulinum toxin substrate 2 (Rac2), NADPH oxidase and reactive oxygen species in diallyl disulphide-induced apoptosis of human leukaemia HL-60 cells. Clinical and experimental pharmacology & physiology 20101201
Effect of diallyldisulphide on an antioxidant enzyme system in Candida species. Canadian journal of microbiology 20101001
Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS medicine 20101001
Anti-invasive activity of diallyl disulfide through tightening of tight junctions and inhibition of matrix metalloproteinase activities in LNCaP prostate cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20100901
Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen. Die Pharmazie 20100901
Optimizing the use of garlic oil as antimicrobial agent on fresh-cut tomato through a controlled release system. Journal of food science 20100901
Allylation of intraerythrocytic hemoglobin by raw garlic extracts. Journal of medicinal food 20100801
Effect of milk on the deodorization of malodorous breath after garlic ingestion. Journal of food science 20100801
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. Journal of medicinal chemistry 20100722
[Inhibitory effect of DADS on transplantation tumor from hepatic carcinoma HePG2 cells in nude mice]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100701
Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis. Journal of agricultural and food chemistry 20100609
Nano-intercalated rhodanese in cyanide antagonism. Nanotoxicology 20100601
Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway. The Journal of nutritional biochemistry 20100501
Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low-density lipoprotein. Molecular nutrition & food research 20100501
When food meets man: the contribution of epigenetics to health. Nutrients 20100501
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells. Journal of cellular and molecular medicine 20100301
Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100301
Influence of garlic or its main active component diallyl disulfide on iron bioavailability and toxicity. Nutrition research (New York, N.Y.) 20100201
[Effects of garlicin on the expression of transcription factor T-bet and GATA-3 in blood lymph cells in rats with allergic rhinitis]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100201
Garlic burn in a patient with trigeminal neuralgia: a case report. European journal of dentistry 20100101
[Epidemiology of contact dermatitis: prevalence of sensitization to different allergens and associated factors]. Actas dermo-sifiliograficas 20100101
Effects of garlic oil on the migration of neutrophil-like cell studied by using a chemotactic gradient Labchip. Journal of biomedicine & biotechnology 20100101
The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells. Journal of experimental & clinical cancer research : CR 20100101
Anti-proliferative effect of LXR agonist T0901317 in ovarian carcinoma cells. Journal of ovarian research 20100101
Characterization of the apoptotic response of human leukemia cells to organosulfur compounds. BMC cancer 20100101
Diallyl disulfide induces caspase-dependent apoptosis via mitochondria-mediated intrinsic pathway in B16F-10 melanoma cells by up-regulating p53, caspase-3 and down-regulating pro-inflammatory cytokines and nuclear factor-κβ-mediated Bcl-2 activation. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20100101
The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease. Lipids in health and disease 20100101
Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery. International journal of cell biology 20100101
Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action. BMC musculoskeletal disorders 20100101
Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. PloS one 20100101
Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice. The Libyan journal of medicine 20100101
Preparation and stability of diallyl trisulfide self-assembled micellar injection. PDA journal of pharmaceutical science and technology 20100101
Dietary phytochemicals and human health. Advances in experimental medicine and biology 20100101
A short-term intervention trial on HIV positive patients using a Sri Lankan classical rasayana drug - Ranahamsa Rasayanaya. Ayu 20100101
Silver-mediated allylic disulfide rearrangement for conjugation of thiols in protic media. The Journal of organic chemistry 20091218
S-allylcysteine modulates the expression of E-cadherin and inhibits the malignant progression of human oral cancer. The Journal of nutritional biochemistry 20091201
Molecular cloning and characterization of dog TRPA1 and AITC stimulate the gastrointestinal motility through TRPA1 in conscious dogs. European journal of pharmacology 20090901
Effects of selected organo-sulfur compounds on melanin formation. Journal of agricultural and food chemistry 20090812
Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target. Life sciences 20090731
Antiapoptotic effects of dietary antioxidants towards N-nitrosopiperidine and N-nitrosodibutylamine-induced apoptosis in HL-60 and HepG2 cells. Journal of applied toxicology : JAT 20090701
Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide. British journal of pharmacology 20090701
Antimicrobial activity of elephant garlic oil against Vibrio cholerae in vitro and in a food model. Bioscience, biotechnology, and biochemistry 20090701
The molecular mechanisms of diallyl disulfide and diallyl sulfide induced hepatocyte cytotoxicity. Chemico-biological interactions 20090615
The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage. American journal of physiology. Gastrointestinal and liver physiology 20090601
Diallyl sulfides in garlic activate both TRPA1 and TRPV1. Biochemical and biophysical research communications 20090508
Diallyl trisulfide selectively causes Bax- and Bak-mediated apoptosis in human lung cancer cells. Environmental and molecular mutagenesis 20090401
Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis. Phytotherapy research : PTR 20090401
Apoptosis induction in human lung adenocarcinoma cells by oil-soluble allyl sulfides: triggers, pathways, and modulators. Environmental and molecular mutagenesis 20090401
Coactivity of sulfide ingredients: a new perspective of the larvicidal activity of garlic essential oil against mosquitoes. Pest management science 20090301
Comparative effects of natural and synthetic diallyl disulfide on apoptosis of human breast-cancer MCF-7 cells. Biotechnology and applied biochemistry 20090201
Effect of diallyl disulfide on cell cycle arrest of human colon cancer SW480 cells. Ai zheng = Aizheng = Chinese journal of cancer 20090201
Concepts of epigenetics in prostate cancer development. British journal of cancer 20090127
Effects of diallyl disulfide (DADS) on expression of apoptosis associated proteins in androgen independent human prostate cancer cells (PC-3). Molecular and cellular biochemistry 20090101
Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Molecular mechanism of diallyl disulfide in cell cycle arrest and apoptosis in HCT-116 colon cancer cells. Journal of biochemical and molecular toxicology 20090101
Results of patch testing in patients diagnosed with oral lichen planus. Journal of cutaneous medicine and surgery 20090101
In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress. International journal of biological sciences 20090101
Phytochemical induction of cell cycle arrest by glutathione oxidation and reversal by N-acetylcysteine in human colon carcinoma cells. Nutrition and cancer 20090101
Proteomics analysis of apoptosis initiation induced by diallyl disulfide in human leukemia HL-60 cells. Ai zheng = Aizheng = Chinese journal of cancer 20090101
Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB. Arthritis research & therapy 20090101
Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure. Oxidative medicine and cellular longevity 20090101
[Tissue distribution of solid lipid nanoparticles loaded garlic oil in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201
Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines. Biologics : targets & therapy 20081201
Diallyl sulfide content and antimicrobial activity against food-borne pathogenic bacteria of chives (Allium schoenoprasum). Bioscience, biotechnology, and biochemistry 20081101
Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds. Cancer letters 20081008
Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-7. Acta pharmacologica Sinica 20081001
[Mechanism reversing MDR of K562/A02 by garlicin combined with erythromycin]. Zhongguo shi yan xue ye xue za zhi 20081001
Synthesis of neoglycoconjugates by the desulfurative rearrangement of allylic disulfides. The Journal of organic chemistry 20080919
Garlic allyl derivatives interact with membrane lipids to modify the membrane fluidity. Journal of biomedical science 20080901
Cancer is a preventable disease that requires major lifestyle changes. Pharmaceutical research 20080901
Substituent effect on the efficiency of desulfurizative rearrangement of allylic disulfides. The Journal of organic chemistry 20080815
Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity. Cancer biology & therapy 20080801
Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic. Bioorganic & medicinal chemistry 20080801
Diallyl disulfide increases histone acetylation in colon cells in vitro and in vivo. Nutrition reviews 20080801
Sensitivity to diallyl disulfide in a Spanish population. Contact dermatitis 20080801
Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells. Carcinogenesis 20080701
Inhibition of ERK and activation of p38 are involved in diallyl disulfide induced apoptosis of leukemia HL-60 cells. Archives of pharmacal research 20080601
Resveratrol in prevention and treatment of common clinical conditions of aging. Clinical interventions in aging 20080601
[Effect of garlicin on the serum levels of interleukin 4 and interferon gamma in allergic rhinitis model in rats]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20080601
Organosulfur compounds alone or in combination with vitamin C protect towards N-nitrosopiperidine- and N-nitrosodibutylamine-induced oxidative DNA damage in HepG2 cells. Chemico-biological interactions 20080509
Effect of Allium sativum (garlic) diallyl disulfide (DADS) on human non-small cell lung carcinoma H1299 cells. Tropical biomedicine 20080401
Do garlic-derived allyl sulfides scavenge peroxyl radicals? Organic & biomolecular chemistry 20080321
Reduced allergy rates in atopic eczema to contact allergens used in both skin products and foods: atopy and the 'hapten-atopy hypothesis'. Contact dermatitis 20080301
Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. The AAPS journal 20080301
Identification of characteristic aroma components of Thai fried chili paste. Journal of agricultural and food chemistry 20080123
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109
In vitro anti-Helicobacter pylori activity of diallyl sulphides and protocatechuic acid. Phytotherapy research : PTR 20080101
Diallyl disulfide induces reversible G2/M phase arrest on a p53-independent mechanism in human colon cancer HCT-116 cells. Oncology reports 20080101
The glial Gomori-positive material is sulfane sulpfur. Folia histochemica et cytobiologica 20080101
Anticancer effects of diallyl trisulfide derived from garlic. Asia Pacific journal of clinical nutrition 20080101
Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine. Cancer genomics & proteomics 20080101
Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats. Molecular vision 20080101
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. BMC pharmacology 20080101
Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration. Cancer cell international 20080101
Diallyl disulfide prevention of cis-Diamminedichloroplatinum-induced nephrotoxicity and leukopenia in rats: potential adjuvant effects. Nutrition and cancer 20080101
Diallyl disulfide (DADS) induces apoptosis in human cervical cancer Ca Ski cells via reactive oxygen species and Ca2+-dependent mitochondria-dependent pathway. Anticancer research 20080101
Butyrate induced cell cycle arrest in bovine cells through targeting gene expression relevant to DNA replication apparatus. Gene regulation and systems biology 20080101
The effect of Allium sativum on ischemic preconditioning and ischemia reperfusion induced cardiac injury. Indian journal of pharmacology 20080101
Neuroprotective effects of garlic a review. The Libyan journal of medicine 20080101
Role of peritoneal macrophages and lymphocytes in the development of hypogonadal osteoporosis in an ovariectomized rat model: possible phytoestrogenic efficacy of oil extract of garlic to preserve skeletal health. Phytotherapy research : PTR 20071101
Bcl-2 small interfering RNA sensitizes cisplatin-resistant human lung adenocarcinoma A549/DDP cell to cisplatin and diallyl disulfide. Acta biochimica et biophysica Sinica 20071101
Synergistic antiyeast activity of garlic oil and allyl alcohol derived from alliin in garlic. Journal of food science 20071101
Hypoglycemic effect of aqueous shallot and garlic extracts in rats with fructose-induced insulin resistance. Journal of clinical biochemistry and nutrition 20071101
Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents. Biological chemistry 20071001
Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070901
Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells. Cancer 20070901
Selective effects of diallyl disulfide, a sulfane sulfur precursor, in the liver and Ehrlich ascites tumor cells. European journal of pharmacology 20070813
Diallyl disulphide depletes glutathione in Candida albicans: oxidative stress-mediated cell death studied by two-photon microscopy. Yeast (Chichester, England) 20070801
[Inhibitory effect of diallyl disulfide on proliferation of human colon cancer cell line SW480 in nude mice]. Ai zheng = Aizheng = Chinese journal of cancer 20070801
Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. Journal of pharmacological sciences 20070801
[Enzyme change in bronchoalveolar lavage fluid of pneumocystis pneumonia rats and the effect of garlicin treatment]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20070801
Diallyl disulfide accelerates adipogenesis in 3T3-L1 cells. International journal of molecular medicine 20070701
Induction of apoptosis and histone hyperacetylation by diallyl disulfide in prostate cancer cell line PC-3. Cancer letters 20070618
Chemical release at the airport and lessons learned from the medical perspective. Journal of hazardous materials 20070601
Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives. Journal of neurochemistry 20070601
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug metabolism and disposition: the biological fate of chemicals 20070601
Two diallyl sulphides derived from garlic inhibit meticillin-resistant Staphylococcus aureus infection in diabetic mice. Journal of medical microbiology 20070601
Effects of preoperatively selected gut decontamination on cardiopulmonary bypass-induced endotoxemia. Chinese journal of traumatology = Zhonghua chuang shang za zhi 20070601
[Effects of garlicin on NIH3T3 cell proliferation and collagen synthesis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070501
Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis : an international journal on programmed cell death 20070401
[Effects of diallyl disulfide on differential expression of apoptosis-associated genes in leukemia cell line HL-60]. Ai zheng = Aizheng = Chinese journal of cancer 20070401
In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes. Biochemical and biophysical research communications 20070302
Allergic contact cheilitis to garlic. Contact dermatitis 20070301
Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial. Archives of internal medicine 20070226
Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytes. Life sciences 20070213
Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway. Journal of agricultural and food chemistry 20070207
Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by diallyl disulfide (DADS). Life sciences 20070116
Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients. Lipids in health and disease 20070101
1,1-Bis(3'-indolyl)-1-(p-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice. Breast cancer research : BCR 20070101
Diallyl disulfide induced signal transducer and activator of transcription 1 expression in human colon cancer colo 205 cells using differential display RT-PCR. Cancer genomics & proteomics 20070101
[Work related sensitization risk in hotel school students, the role of garlic]. Giornale italiano di medicina del lavoro ed ergonomia 20070101
Influence of diallyl disulphide on temporal patterns of circulatory lipid peroxidation products and antioxidants in N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Toxicology mechanisms and methods 20070101
Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. Journal of ethnopharmacology 20061206
Induction of apoptosis and transient increase of phosphorylated MAPKs by diallyl disulfide treatment in human nasopharyngeal carcinoma CNE2 cells. Archives of pharmacal research 20061201
Simultaneous determination of diallyl trisulfide and diallyl disulfide in rat blood by gas chromatography with electron-capture detection. Die Pharmazie 20061201
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells. The Journal of nutritional biochemistry 20061101
Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAF1 expression in vivo and in vitro. Acta pharmacologica Sinica 20061101
Diallyl disulfide increases CDKN1A promoter-associated histone acetylation in human colon tumor cell lines. Journal of agricultural and food chemistry 20061004
Different activation patterns of rat xenobiotic metabolism genes by two constituents of garlic. Carcinogenesis 20061001
Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds. Journal of agricultural and food chemistry 20060906
Clinical study on effect of Garlicin in stabilizing the carotid artery atherosclerotic plaque in patients with primary hypertension and coronary artery disease. Chinese journal of integrative medicine 20060901
[Effect of diallyl disulfide on the expression and secretion of VEGF in HL-60 cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20060901
Antidiabetic effect of garlic oil but not diallyl disulfide in rats with streptozotocin-induced diabetes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801
Garlic compound, diallyl disulfide induces cell cycle arrest in prostate cancer cell line PC-3. Molecular and cellular biochemistry 20060801
Fumigant activity of plant essential oils and components from horseradish (Armoracia rusticana), anise (Pimpinella anisum) and garlic (Allium sativum) oils against Lycoriella ingenua (Diptera: Sciaridae). Pest management science 20060801
Allergic contact dermatitis to plants in a Spanish dermatology department: a 7-year review. Contact dermatitis 20060801
Garlic allyl sulfides display differential modulation of rat cytochrome P450 2B1 and the placental form glutathione S-transferase in various organs. Journal of agricultural and food chemistry 20060712
[Study of organosulfur compounds in fresh garlic by gas chromatography/mass spectrometry incorporated with temperature-programmable cold on-column injection]. Se pu = Chinese journal of chromatography 20060701
Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition. Toxicology letters 20060601
Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601
Dietary agents as histone deacetylase inhibitors. Molecular carcinogenesis 20060601
Effects of garlic oil and two of its major organosulfur compounds, diallyl disulfide and diallyl trisulfide, on intestinal damage in rats injected with endotoxin. Toxicology and applied pharmacology 20060515
DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages. Journal of agricultural and food chemistry 20060503
Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane. Current drug targets 20060401
[Effect of diallyl disulfide on expression and secretion of VEGF in HL-60 leukemic cells]. Zhongguo shi yan xue ye xue za zhi 20060401
The role of Ca2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18). Neurochemical research 20060301
Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis 20060201
Chemoprevention of rat prostate carcinogenesis by diallyl disulfide, an organosulfur compound of garlic. Biological & pharmaceutical bulletin 20060201
Antiproliferative effect of diallyl disulfide (DADS) on prostate cancer cell line LNCaP. Cell biochemistry and function 20060101
Diallyl disulfide inhibits WEHI-3 leukemia cells in vivo. Anticancer research 20060101
Home gardening may be a risk factor for contact dermatitis to Alstroemeria. Allergologia et immunopathologia 20060101
Garlic-derived organosulfides induce cytotoxicity, apoptosis, cell cycle arrest and oxidative stress in human colon carcinoma cell lines. Neoplasma 20060101
Radioprotective activity of naturally occurring organosulfur compounds. Tumori 20060101
The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. Journal of medicinal food 20060101
Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803. Cellular & molecular biology letters 20060101
Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin. The Journal of biological chemistry 20051216
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis. Cancer research 20051215
Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20051201
Effect of garlic oil and four of its compounds on rumen microbial fermentation. Journal of dairy science 20051201
The role of reactive oxygen species (ROS) production on diallyl disulfide (DADS) induced apoptosis and cell cycle arrest in human A549 lung carcinoma cells. Mutation research 20051111
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an 'in vitro' replicative system. Antiviral research 20051101
Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Molecular cancer therapeutics 20050901
Pungent products from garlic activate the sensory ion channel TRPA1. Proceedings of the National Academy of Sciences of the United States of America 20050823
Composition, stability, and bioavailability of garlic products used in a clinical trial. Journal of agricultural and food chemistry 20050810
Effects of garlicin on apoptosis in rat model of colitis. World journal of gastroenterology 20050807
[Antitumor effect of diallyl disulfide on human gastric cancer MGC803 cells xenograft in nude mice]. Ai zheng = Aizheng = Chinese journal of cancer 20050801
Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050701
Differential effects of diallyl disulfide on neuronal cells depend on its concentration. Toxicology 20050701
A case-control study in Shanghai of fruit and vegetable intake and endometrial cancer. British journal of cancer 20050606
Fumigant activity of plant essential oils and components from garlic (Allium sativum) and clove bud (Eugenia caryophyllata) oils against the Japanese termite (Reticulitermes speratus Kolbe). Journal of agricultural and food chemistry 20050601
Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein BimEL and induces apoptosis. British journal of cancer 20050509
The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3). Molecular cancer therapeutics 20050501
Analytical method for appreciation of garlic therapeutic potential and for validation of a new formulation. Journal of pharmaceutical and biomedical analysis 20050429
Modulation of cytokine secretion by garlic oil derivatives is associated with suppressed nitric oxide production in stimulated macrophages. Journal of agricultural and food chemistry 20050406
Growth suppressing effect of garlic compound diallyl disulfide on prostate cancer cell line (PC-3) in vitro. Biological & pharmaceutical bulletin 20050401
Differential effects of organosulfur compounds from garlic oil on nitric oxide and prostaglandin E2 in stimulated macrophages. Nutrition (Burbank, Los Angeles County, Calif.) 20050401
Allicin and allicin-derived garlic compounds increase breath acetone through allyl methyl sulfide: use in measuring allicin bioavailability. Journal of agricultural and food chemistry 20050323
Garlic-fingered chefs. Contact dermatitis 20050301
Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin. Phytotherapy research : PTR 20050301
Protective effect of diallyl disulfide on oxidative stress-injured neuronally differentiated PC12 cells. Brain research. Molecular brain research 20050218
Inhibition by allyl sulfides and crushed garlic of O6-methylguanine formation in liver DNA of dimethylnitrosamine-treated rats. Nutrition and cancer 20050101
Allyl disulfide as donor and cyanide as acceptor of sulfane sulfur in the mouse tissues. Pharmacological reports : PR 20050101
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. Breast cancer research : BCR 20050101
Differential effects of allyl sulfides from garlic essential oil on cell cycle regulation in human liver tumor cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041201
Repetitive treatments of colon HT-29 cells with diallyl disulfide induce a prolonged hyperacetylation of histone H3 K14. Annals of the New York Academy of Sciences 20041201
[The experimental study of garlicin in treating Pneumocystis carinii pneumonia in rats]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20041201
Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals. Free radical biology & medicine 20041115
Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug resistance-associated protein 2 expression. Biochemical and biophysical research communications 20041112
Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review. Mutation research 20041102
Use of gloves in protection from diallyl disulphide allergy. The Australasian journal of dermatology 20041101
Inhibition of the benzo[a]pyrene-induced toxicity by allyl sulfides in human epidermal keratinocytes. Biotechnology letters 20041101
Antioxidant effects of sulfur-containing amino acids. Yonsei medical journal 20041031
Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001
Diallyl disulfide-induced G2/M arrest of human gastric cancer MGC803 cells involves activation of p38 MAP kinase pathways. World journal of gastroenterology 20040915
Post-initiation modulating effects of allyl sulfides in rat hepatocarcinogenesis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040901
Improvement of scopolamine-induced memory impairment by Z-ajoene in the water maze in mice. Pharmacology, biochemistry, and behavior 20040801
Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene 20040722
Enhancement of diallyl disulfide-induced apoptosis by inhibitors of MAPKs in human HepG2 hepatoma cells. Biochemical pharmacology 20040715
Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines. Carcinogenesis 20040701
Influence of organosulphur compounds from garlic on the secretion of matrix metalloproteinases and their inhibitor TIMP-1 by cultured HUVEC cells. Cell biology and toxicology 20040701
Antioxidative and antiglycative effects of six organosulfur compounds in low-density lipoprotein and plasma. Journal of agricultural and food chemistry 20040602
[Preventive effect and clinical significance of garlicin injection on mechanical ventilator-associated low respiratory tract deep-seated fungal infection]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040601
Biological activity of volatile di-n-propyl disulfide from seeds of neem, Azadirachta indica (Meliaceae), to two species of stored grain pests, Sitophilus oryzae (L.) and Tribolium castaneum (Herbst). Journal of economic entomology 20040601
Solid-phase microextraction-gas chromatographic-mass spectrometric analysis of garlic oil obtained by hydrodistillation. Journal of chromatography. A 20040514
The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040501
[The initiation of G2/M checkpoint by diallyl disulfide requires the activation of p38 MAP kinase in HL-60 cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040501
[Garlicin and formocresol in the treatment of chronic periapical periodontitis]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20040401
Selective expression of glutathione S-transferase genes in the murine gastrointestinal tract in response to dietary organosulfur compounds. Carcinogenesis 20040301
Synthesis of radioiodine labeled dibenzyl disulfide for evaluation of tumor cell uptake. Bioorganic & medicinal chemistry 20040301
[Diallyl disulfide-induced G2/M arrest of human gastric cancer MGC803 cells involves activation of p38 MAP kinase pathways]. Ai zheng = Aizheng = Chinese journal of cancer 20040201
Garlic metabolites fail to inhibit the activation of the transcription factor NF-kappaB and subsequent expression of the adhesion molecule E-selectin in human endothelial cells. European journal of nutrition 20040201
Diallyl disulfide (DADS) enhances gap-junctional intercellular communication by both direct and indirect mechanisms in rat liver cells. Carcinogenesis 20040101
Mechanism and kinetics of synthesis of allicin. Die Pharmazie 20040101
Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3. Nutrition and cancer 20040101
Conjugated docosahexaenoic acid suppresses KPL-1 human breast cancer cell growth in vitro and in vivo: potential mechanisms of action. Breast cancer research : BCR 20040101
Garlic's ability to prevent in vitro Cu2+-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu2+-chelation. Nutrition journal 20040101
Inhibition of cyclooxygenase-2 by diallyl sulfides (DAS) in HEK 293T cells. Journal of applied genetics 20040101
Diallyldisulfide-induced calcium response of HL-60 human promyelocytes. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101
Anticarcinogenic properties of garlic: a review. Critical reviews in food science and nutrition 20040101
Chemoprotective effect of diallyl trisulfide from garlic against carbon tetrachloride-induced acute liver injury of rats. BioFactors (Oxford, England) 20040101
Effects of garlic powders with varying alliin contents on hepatic drug metabolizing enzymes in rats. Journal of agricultural and food chemistry 20031217
Garlic extract and two diallyl sulphides inhibit methicillin-resistant Staphylococcus aureus infection in BALB/cA mice. The Journal of antimicrobial chemotherapy 20031201
Hepatic metabolism of diallyl disulphide in rat and man. Xenobiotica; the fate of foreign compounds in biological systems 20031201
Prevention and therapy of fungal infection in severe acute pancreatitis: A prospective clinical study. World journal of gastroenterology 20031115
Comparative study of extraction techniques for determination of garlic flavor components by gas chromatography-mass spectrometry. Analytical and bioanalytical chemistry 20031001
Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer research 20030915
Photocontact allergy to diallyl disulfide. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030901
Biofactors in the Mediterranean diet. Clinical chemistry and laboratory medicine 20030801
Diallyl disulfide ameliorates gentamicin-induced oxidative stress and nephropathy in rats. European journal of pharmacology 20030718
Effects of hydrocolloid thickeners on the perception of savory flavors. Journal of agricultural and food chemistry 20030507
Inhibition of H-ras as a treatment for experimental brain C6 glioma. Brain research. Molecular brain research 20030317
Protective action on human LDL against oxidation and glycation by four organosulfur compounds derived from garlic. Lipids 20030301
A comparative study of allitin and garlic on lipid turnover in a teleost, Anabas testudineus (Bloch). Indian journal of experimental biology 20030301
Mechanism-based in vitro screening of potential cancer chemopreventive agents. Mutation research 20030101
Prevention of chemical carcinogen DNA binding and inhibition of nuclear RNA polymerase activity by organosulfur compounds as the possible mechanisms for their anticancer initiation and proliferation effects. Cancer detection and prevention 20030101
Cell death mechanisms in the human opportunistic pathogen Candida albicans. The Journal of eukaryotic microbiology 20030101
Antioxidant and antimicrobial effects of four garlic-derived organosulfur compounds in ground beef. Meat science 20030101
A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds. Journal of agricultural and food chemistry 20021218
Protective effect of three diallyl sulphides against glucose-induced erythrocyte and platelet oxidation, and ADP-induced platelet aggregation. Thrombosis research 20021215
In vivo metabolism of diallyl disulphide in the rat: identification of two new metabolites. Xenobiotica; the fate of foreign compounds in biological systems 20021201
Alleviation of cyclophosphamide-induced urotoxicity by naturally occurring sulphur compounds. Journal of experimental & clinical cancer research : CR 20021201
Eat your garlic! Integrative cancer therapies 20021201
Inhibition of heterocyclic aromatic amine formation in fried ground beef patties by garlic and selected garlic-related sulfur compounds. Journal of food protection 20021101
Nonenzymatic antioxidant activity of four organosulfur compounds derived from garlic. Journal of agricultural and food chemistry 20021009
Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic. Carcinogenesis 20021001
Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic. Carcinogenesis 20020801
Role of Ca(2+) in diallyl disulfide-induced apoptotic cell death of HCT-15 cells. Experimental & molecular medicine 20020731
Effects of food materials on removal of Allium-specific volatile sulfur compounds. Journal of agricultural and food chemistry 20020619
Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages. Life sciences 20020614
[Effect of garlicin on adhesion molecules expression and deformability of peripheral neutrophils in patients with acute cerebral infarction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020601
Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells. The Journal of nutrition 20020401
Systemic contact dermatitis from diallyl disulfide. Contact dermatitis 20020201
Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats. Journal of agricultural and food chemistry 20020116
Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells. Biochemical pharmacology 20020101
Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. Blood cells, molecules & diseases 20020101
Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in human promyelocytic leukemia cells. The American journal of Chinese medicine 20020101
Anti-tumour-promoting action of Allium constituents. IARC scientific publications 20020101
Effect of garlic on cardiovascular disorders: a review. Nutrition journal 20020101
Modulation of cytochrome P4501-mediated bioactivation of benzo[a]pyrene by volatile allyl sulfides in human hepatoma cells. Bioscience, biotechnology, and biochemistry 20011001
Photoallergic contact dermatitis from diallyl disulfide. Contact dermatitis 20010901
Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction. Mutation research 20010822
Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant sub-populations. Carcinogenesis 20010801
Screening of organosulfur compounds as inhibitors of human CYP2A6. Drug metabolism and disposition: the biological fate of chemicals 20010701
In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. Journal of medical microbiology 20010701
[The cause of integrated traditional Chinese and Western medicine and I]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010701
Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601
Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines. Carcinogenesis 20010601
Effect of diallyl sulfide and diallyl disulfide, the active principles of garlic, on the aflatoxin B(1)-induced DNA damage in primary rat hepatocytes. Toxicology letters 20010531
In vitro activity of garlic oil and four diallyl sulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae. The Journal of antimicrobial chemotherapy 20010501
Effects of diallyl disulfide and other donors of sulfane sulfur on the proliferation of human hepatoma cell line (HepG2). Neoplasma 20010101
Induction of histone acetylation in rat liver and hepatoma by organosulfur compounds including diallyl disulfide. Anticancer research 20010101
Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinone reductase and glutathione transferase in rat tissues. Nutrition and cancer 20010101
Inhibition of CYP2E1 reverses CD4+ T-cell alterations in trichloroethylene-treated MRL+/+ mice. Toxicological sciences : an official journal of the Society of Toxicology 20000401
Chemoprevention of colon carcinogenesis by organosulfur compounds. Cancer research 19930801
Allyl compounds selectively killed human immunodeficiency virus (type 1)-infected cells. Biochemical and biophysical research communications 19930730

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