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130-16-5

130-16-5 | 8-Quinolinol, 5-chloro-

CAS No: 130-16-5 Catalog No: AG000TUR MDL No:MFCD00006788

Product Description

Catalog Number:
AG000TUR
Chemical Name:
8-Quinolinol, 5-chloro-
CAS Number:
130-16-5
Molecular Formula:
C9H6ClNO
Molecular Weight:
179.6030
MDL Number:
MFCD00006788
IUPAC Name:
5-chloroquinolin-8-ol
InChI:
InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H
InChI Key:
CTQMJYWDVABFRZ-UHFFFAOYSA-N
SMILES:
Clc1ccc(c2c1cccn2)O
EC Number:
204-978-1
UNII:
BPF36H1G6S

Properties

Complexity:
165  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
179.014g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
179.603g/mol
Monoisotopic Mass:
179.014g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
33.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9  

Literature

Title Journal
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction. Journal of medicinal chemistry 20130328
Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode. Journal of fluorescence 20120901
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. The Journal of antimicrobial chemotherapy 20120201
Investigation on the pharmacological profile of antimony(III) complexes with hydroxyquinoline derivatives: anti-trypanosomal activity and cytotoxicity against human leukemia cell lines. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20110801
Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by ³⁵Cl NQR, ¹H-¹⁷O and ¹H-¹⁴N NQDR and DFT/QTAIM. Journal of molecular modeling 20110701
Identifying chelators for metalloprotein inhibitors using a fragment-based approach. Journal of medicinal chemistry 20110127
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Grafting aluminum(III) 8-hydroxyquinoline derivatives on MCM-41 mesoporous silica for tuning of the light emitting color. Journal of colloid and interface science 20100615
5-Chloro-8-hydroxy-quinolinium nitrate. Acta crystallographica. Section E, Structure reports online 20090601
Vibrational spectroscopic investigations, ab initio and DFT studies on 7-bromo-5-chloro-8-hydroxyquinoline. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090501
Bis(μ-5-chloro-quinolin-8-olato)-κN,O:O;κO:N,O-bis-[(acetato-κO,O')lead(II)]. Acta crystallographica. Section E, Structure reports online 20090301
Outlook on Thailand's genomics and computational biology research and development. PLoS computational biology 20080701
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands. The Biochemical journal 20071101
In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy 20070301
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes. Environmental science & technology 20060315

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