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10190-99-5

10190-99-5 | Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, sodium salt (1:1)

CAS No: 10190-99-5 Catalog No: AG0005VT MDL No:

Product Description

Catalog Number:
AG0005VT
Chemical Name:
Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, sodium salt (1:1)
CAS Number:
10190-99-5
Molecular Formula:
C17H10NNaO7
Molecular Weight:
363.2536
IUPAC Name:
sodium;8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylate
InChI:
InChI=1S/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1
InChI Key:
BQVOPWJSBBMGBR-UHFFFAOYSA-M
SMILES:
COc1cccc2c1cc([N+](=O)[O-])c1c2c2OCOc2cc1C(=O)[O-].[Na+]
EC Number:
233-463-4
UNII:
KTM3D3H78E

Properties

Complexity:
544  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
363.035g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
363.257g/mol
Monoisotopic Mass:
363.035g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
114A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells. Toxicology letters 20180701
Plasma-specific microRNA response induced by acute exposure to aristolochic acid I in rats. Archives of toxicology 20170301
Urinary Time- or Dose-Dependent Metabolic Biomarkers of Aristolochic Acid-Induced Nephrotoxicity in Rats. Toxicological sciences : an official journal of the Society of Toxicology 20170301
Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells. Carcinogenesis 20160701
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo. Toxicology 20160217
Aristolochic Acid I Causes Testis Toxicity by Inhibiting Akt and ERK1/2 Phosphorylation. Chemical research in toxicology 20160119
Human bone morphogenetic protein-7 does not counteract aristolochic acid-induced renal toxicity. Journal of applied toxicology : JAT 20151201
The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats. Archives of toxicology 20151101
Impairment of the Cellular Distribution and Stability of the Erythropoietin Receptor Through the Direct Targeting of Aristolochic Acid. Toxicological sciences : an official journal of the Society of Toxicology 20150901
Baicalin Protects Mice from Aristolochic Acid I-Induced Kidney Injury by Induction of CYP1A through the Aromatic Hydrocarbon Receptor. International journal of molecular sciences 20150701
Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. Toxicology in vitro : an international journal published in association with BIBRA 20150201
Aristolochic acid-induced apoptosis and G2 cell cycle arrest depends on ROS generation and MAP kinases activation. Archives of toxicology 20150101
An exploratory evaluation of the utility of transcriptional and urinary kidney injury biomarkers for the prediction of aristolochic acid-induced renal injury in male rats. Veterinary pathology 20140501
Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway. Toxicology 20140406
Downregulation of connective tissue growth factor by LPS/IFN-γ-induced nitric oxide is reversed by aristolochic acid treatment in glomerular mesangial cells via STAT-1α and NF-κB signaling. Chemico-biological interactions 20140305
Autophagy induction promotes aristolochic acid-I-induced renal injury in vivo and in vitro. Toxicology 20131004
Possible role of mtDNA depletion and respiratory chain defects in aristolochic acid I-induced acute nephrotoxicity. Toxicology and applied pharmacology 20130115
Novel assays for detection of urinary KIM-1 in mouse models of kidney injury. Toxicological sciences : an official journal of the Society of Toxicology 20130101
Organic anion transporter 1 (OAT1) involved in renal cell transport of aristolochic acid I. Human & experimental toxicology 20120801
Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA 20120801
ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues. Environmental and molecular mutagenesis 20120801
Aristoxazole analogues. Conversion of 8-nitro-1-naphthoic acid to 2-methylnaphtho[1,2-d]oxazole-9-carboxylic acid: comments on the chemical mechanism of formation of DNA adducts by the aristolochic acids. Journal of natural products 20120727
Gremlin-mediated decrease in bone morphogenetic protein signaling promotes aristolochic acid-induced epithelial-to-mesenchymal transition (EMT) in HK-2 cells. Toxicology 20120716
Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: an important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy. Biochemical and biophysical research communications 20120713
Acute renal failure due to an aristolochic acid containing herbal remedy. Nephrology (Carlton, Vic.) 20120701
Clinical and pathological spectrums of aristolochic acid nephropathy. Clinical nephrology 20120701
JNK-dependent AP-1 activation is required for aristolochic acid-induced TGF-β1 synthesis in human renal proximal epithelial cells. American journal of physiology. Renal physiology 20120615
Aristolochic acid nephropathy. BMJ (Clinical research ed.) 20120615
Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® rats. Environmental and molecular mutagenesis 20120601
Developmental nephrotoxicity of aristolochic acid in a zebrafish model. Toxicology and applied pharmacology 20120515
Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutation research 20120318
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid. Kidney international 20120301
Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy. Kidney international 20120301
Drugs and AKI. Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20120301
Evaluation of microwave-assisted extraction for aristolochic acid from Aristolochiae Fructus by chromatographic analysis coupled with nephrotoxicity studies. Biomedical chromatography : BMC 20120201
Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2. Toxicological sciences : an official journal of the Society of Toxicology 20120201
Glutathione S-transferases T1 null genotype is associated with susceptibility to aristolochic acid nephropathy. International urology and nephrology 20120201
Aristolochic acid I metabolism in the isolated perfused rat kidney. Chemical research in toxicology 20120113
Altered tight junctions and fence function in NRK-52E cells induced by aristolochic acid. Human & experimental toxicology 20120101
Aristolochic acid nephropathy: variation in presentation and prognosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101
Risk of urinary tract carcinoma in aristolochic acid nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101
Renal microvascular injury in chronic aristolochic acid nephropathy and protective effects of Cozaar. Renal failure 20120101
Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells. PloS one 20120101
Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts. PloS one 20120101
[Development of gastric precancerous lesion animal model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101
Critical role of organic anion transporters 1 and 3 in kidney accumulation and toxicity of aristolochic acid I. Molecular pharmaceutics 20111205
Ergosta-4,6,8(14),22-tetraen-3-one isolated from Polyporus umbellatus prevents early renal injury in aristolochic acid-induced nephropathy rats. The Journal of pharmacy and pharmacology 20111201
Association between urothelial carcinoma after kidney transplantation and aristolochic acid exposure: the potential role of aristolochic acid in HRas and TP53 gene mutations. Transplantation proceedings 20111201
[Clinical characteristics and long-term follow-up analysis of three cases with newborn aristolochic acid nephropathy]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20111101
[Experts comment]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20111101
[Determination of aristolochic acids A and B in Chinese herbals and traditional Chinese patent medicines using ultra high performance liquid chromatography-triple quadrupole mass spectrometry]. Se pu = Chinese journal of chromatography 20111101
Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice. Chemical research in toxicology 20111017
Urothelial carcinoma associated with Balkan endemic nephropathy. A worldwide disease. Pathologie-biologie 20111001
Interaction studies of aristolochic acid I with human serum albumin and the binding site of aristolochic acid I in subdomain IIA. International journal of biological macromolecules 20111001
Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells. Toxicology 20110905
Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo. Matrix biology : journal of the International Society for Matrix Biology 20110901
Physiological and molecular characterization of aristolochic acid transport by the kidney. The Journal of pharmacology and experimental therapeutics 20110801
Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20110801
Aristolochic acid I and ochratoxin A differentially regulate VEGF expression in porcine kidney epithelial cells--the involvement of SP-1 and HIFs transcription factors. Toxicology letters 20110728
Aristolochic acid downregulates monocytic matrix metalloproteinase-9 by inhibiting nuclear factor-κB activation. Chemico-biological interactions 20110715
Determination of dissociation constants of aristolochic acid I and II by capillary electrophoresis with carboxymethyl chitosan-coated capillary. Talanta 20110715
The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases. Environmental and molecular mutagenesis 20110701
Aristolochic acid I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells. Toxicology in vitro : an international journal published in association with BIBRA 20110601
Effect of thapsigargin on Ca²+ fluxes and viability in human prostate cancer cells. Journal of receptor and signal transduction research 20110601
Genetic loci that affect aristolochic acid-induced nephrotoxicity in the mouse. American journal of physiology. Renal physiology 20110601
Kinetics of aristolochic acid I after oral administration of Radix Aristolochiae or Guanxinsuhe preparation in canines. Journal of ethnopharmacology 20110517
Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model. Toxicological sciences : an official journal of the Society of Toxicology 20110501
Aristolochic acid I suppressed iNOS gene expression and NF-κB activation in stimulated macrophage cells. Toxicology letters 20110425
Nephropathy associated with use of a Chinese herbal product containing aristolochic acid. The Medical journal of Australia 20110404
Occupational kidney disease among Chinese herbalists exposed to herbs containing aristolochic acids. Occupational and environmental medicine 20110401
Proteomics investigation on aristolochic acid nephropathy: a case study on rat kidney tissues. Analytical and bioanalytical chemistry 20110401
Chinese herbal medicines, aristolochic acid and Balkan endemic nephropathy. Occupational and environmental medicine 20110401
Renal liver-type fatty acid binding protein (L-FABP) attenuates acute kidney injury in aristolochic acid nephrotoxicity. The American journal of pathology 20110301
Aristolochic acid-induced destruction of organic ion transporters and fatty acid metabolic disorder in the kidney of rats. Toxicology letters 20110225
Inhibition of aquaporin-1 expression by RNAi protects against aristolochic acid I-induced apoptosis in human proximal tubular epithelial (HK-2) cells. Biochemical and biophysical research communications 20110204
Comparative nephrotoxicity of aristolochic acid and tetrandrine in vitro and in vivo. International journal of toxicology 20110201
[A new aristolochic acid derivative from Asarum himalaicum]. Yao xue xue bao = Acta pharmaceutica Sinica 20110201
A novel and specific method for the determination of aristolochic acid-derived DNA adducts in exfoliated urothelial cells by using ultra performance liquid chromatography-triple quadrupole mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115
Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice. International journal of cancer 20110101
The molecular mechanism of leptin secretion and expression induced by aristolochic acid in kidney fibroblast. PloS one 20110101
Protective effect of prostaglandin E1 on renal microvascular injury in rats of acute aristolochic acid nephropathy. Renal failure 20110101
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases. Neuro endocrinology letters 20110101
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver. Neuro endocrinology letters 20110101
Identification of a reduction product of aristolochic acid: implications for the metabolic activation of carcinogenic aristolochic acid. Journal of natural products 20101227
Determination of aristolochic acid in urine using hollow fiber liquid-phase microextraction combined with high-performance liquid chromatography. Biomedical chromatography : BMC 20101201
[Trace analysis of aristolochic acid A]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents. International journal of cancer 20100901
[Studies on the chemical constituents from the fruit of Aristolochia debilis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801
Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity. Toxins 20100801
Aristolochic acid suppresses DNA repair and triggers oxidative DNA damage in human kidney proximal tubular cells. Oncology reports 20100701
Effect of m-3M3FBS on Ca²⁺ movement in PC3 human prostate cancer cells. The Chinese journal of physiology 20100630
Effect of nortriptyline on Ca²⁺ handling in SIRC rabbit corneal epithelial cells. The Chinese journal of physiology 20100630
Fatal renal failure due to the Chinese herb 'GuanMu Tong' (Aristolochia manshuriensis): autopsy findings and review of literature. Forensic science international 20100615
Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA 20100601
Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model. The FEBS journal 20100601
«Suspects» in etiology of endemic nephropathy: aristolochic acid versus mycotoxins. Toxins 20100601
Liquid chromatography/mass spectrometry for investigating the biochemical effects induced by aristolochic acid in rats: the plasma metabolome. Rapid communications in mass spectrometry : RCM 20100515
[Differential changes of intrarenal oxygenation in rat models of acute tubular necrosis caused by aristolochic acid and gentamicin]. Zhonghua yi xue za zhi 20100504
Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse. Drug metabolism and disposition: the biological fate of chemicals 20100501
Chronic kidney disease associated with environmental toxins and exposures. Advances in chronic kidney disease 20100501
Mechanism of chronic aristolochic acid nephropathy: role of Smad3. American journal of physiology. Renal physiology 20100401
Early detection of Balkan endemic nephropathy in Bosanska Posavina. Bosnian journal of basic medical sciences 20100401
Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry. Talanta 20100315
Aristolochic acid nephropathy revisited: a place for innate and adaptive immunity? Histopathology 20100301
Traditional Chinese practitioner breaches Medicine Act. BMJ (Clinical research ed.) 20100219
Population-based case-control study of Chinese herbal products containing aristolochic acid and urinary tract cancer risk. Journal of the National Cancer Institute 20100203
A liquid chromatography/tandem mass spectrometry method for determination of aristolochic acid-I in rat plasma. Biomedical chromatography : BMC 20100201
Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells. Acta pharmacologica Sinica 20100201
[Effect of bone morphogenetic protein-7 on aristolochic acid induced renal tubular epithelial cells transdifferentiation]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100201
Activation of p53 promotes renal injury in acute aristolochic acid nephropathy. Journal of the American Society of Nephrology : JASN 20100101
Low-dose darbepoetin alpha attenuates progression of a mouse model of aristolochic acid nephropathy through early tubular protection. Nephron. Experimental nephrology 20100101
Therapeutic remedies based on Aristolochia clematitis in the main foci of Balkan endemic nephropathy in Romania. Nephron. Clinical practice 20100101
Interactions of human organic anion transporters with aristolochic acids. Journal of pharmacological sciences 20100101
beta-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism. Acta pharmacologica Sinica 20091101
Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. Toxicology 20091001
Simple and rapid analysis of aristolochic acid contained in crude drugs and Kampo formulations with solid-phase extraction and HPLC photodiode-array detection. Journal of natural medicines 20091001
Molecular characterization of preneoplastic lesions provides insight on the development of renal tumors. The American journal of pathology 20091001
Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2--a global assessment based on bibliographic sources. Journal of ethnopharmacology 20090817
[Organic anion transporter system mediates the transport of aristolochic acid in tubular epithelial cells]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20090801
Stress-induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide. Journal of neurochemistry 20090601
De novo urothelial carcinoma in kidney transplant patients with end-stage aristolochic acid nephropathy in China. Transplantation proceedings 20090601
Determination of aristolochic acid I and its metabolites in cell culture with a hyphenated high-performance liquid chromatographic technique for cell toxicology. Talanta 20090515
Analysis of aristolochic acids by CE-MS with carboxymethyl chitosan-coated capillary. Electrophoresis 20090501
p53 mutations as fingerprints for aristolochic acid: an environmental carcinogen in endemic (Balkan) nephropathy. Mutation research 20090426
Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid. Nephrology (Carlton, Vic.) 20090401
Determination of aristolochic acid I in rat urine and plasma by high-performance liquid chromatography with fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401
[Effects of Hirsutella sinensis on TGF-beta1 and Snail expressions and transdifferentiation of tubular epithelial-myofibroblast in renal tissue of rats with chronic aristolochic acid nephropathy]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090401
TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours. International journal of cancer 20090215
Characterization of chemoreceptive protein binding to an oviposition stimulant using a fluorescent micro-binding assay in a butterfly. FEBS letters 20090122
Increased mortality risk for cancers of the kidney and other urinary organs among Chinese herbalists. Journal of epidemiology 20090101
[Aristolochic acid nephropathy]. Przeglad lekarski 20090101
Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles. BMC bioinformatics 20090101
Molecular markers in upper urothelial carcinoma associated to Balkan endemic nephropathy. Aristolochic acid as the major risk factor of the worldwide disease. TheScientificWorldJournal 20090101
Aristolochic acid nephropathy due to herbal drug intake manifested differently as Fanconi's syndrome and end-stage renal failure--a 7-year follow-up. Clinical nephrology 20081201
Quantification of aristolochic acid-derived DNA adducts in rat kidney and liver by using liquid chromatography-electrospray ionization mass spectrometry. Mutation research 20081110
The phospholipase A inhibitor, aristolochic acid, disrupts cortical microtubule arrays and root growth in Arabidopsis. Plant biology (Stuttgart, Germany) 20081101
Induction of P450 1A by 3-methylcholanthrene protects mice from aristolochic acid-I-induced acute renal injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53. Toxicology and applied pharmacology 20081001
Phospholipase A2beta mediates light-induced stomatal opening in Arabidopsis. Journal of experimental botany 20081001
Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid. Neuro endocrinology letters 20081001
[Effects of exogenous epidermal growth factor (EGF) on growth inhibition induced by aristolochic acid I (AA-I) in renal proximal tubular epithelial cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
[Study of pharmacokinetics of aristolochic acid I and II in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
Comparative study on the aristolochic acid I content of Herba Asarifor safe use. Phytomedicine : international journal of phytotherapy and phytopharmacology 20080901
[Effects of cytochrome P450 isozymes on aristolochic acid renal cytotoxicity]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901
Patterns of interstitial inflammation during the evolution of renal injury in experimental aristolochic acid nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801
Species-specific toxicity of aristolochic acid (AA) in vitro. Toxicology in vitro : an international journal published in association with BIBRA 20080801
Involvement of p38 MAPK phosphorylation and nitrate formation in aristolochic acid-mediated antiplatelet activity. Planta medica 20080801
Protective effect of erythropoietin against aristolochic acid-induced apoptosis in renal tubular epithelial cells. European journal of pharmacology 20080707
Aristolochic acid nephropathy: a worldwide problem. Kidney international 20080701
Ischemic injury underlies the pathogenesis of aristolochic acid-induced acute kidney injury. Translational research : the journal of laboratory and clinical medicine 20080701
Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity. Kidney international 20080601
Biotransformation enzymes in development of renal injury and urothelial cancer caused by aristolochic acid. Kidney international 20080601
Cellulase elicitor induced accumulation of capsidiol in Capsicum annumm L. suspension cultures. Biotechnology letters 20080501
[Aristolochic acid induces renal tubular injury and inhibits expression of bone morphogenetic protein-7 mRNA in renal tissue of rats]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080501
[Wenyang Huoxue Recipe up-regulates the expression of angiopoietin-1 mRNA in rats with chronic aristolochic acid nephropathy]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080501
[Observation of penetration, distribution and accumulation in human renal proximal tubular epithelial cells by aristololactam-I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401
Aristolochic acid induced changes in the metabolic profile of rat urine. Journal of pharmaceutical and biomedical analysis 20080313
[Differentiation of mesenchymal stem cells into vascular endothelial cells in treatment of chronic aristolochic acid nephropathy: experiment with rats]. Zhonghua yi xue za zhi 20080311
Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation. Kidney international 20080301
Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080301
Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: a case series with 15-year follow-up. American journal of kidney diseases : the official journal of the National Kidney Foundation 20080301
Mycotoxic and aristolochic acid theories of the development of endemic nephropathy. Arhiv za higijenu rada i toksikologiju 20080301
[Synthesis and mass spectrometric analysis of aristolochic acid-deoxyguanosine adducts]. Yao xue xue bao = Acta pharmaceutica Sinica 20080301
[Study on homologous bone marrow mesenchymal stem cells in repairing peri-tubular capillary cluster]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080201
[Analysis of aristolochic acid A from the aerial and underground parts of Asarum by UPLC-UV]. Yao xue xue bao = Acta pharmaceutica Sinica 20080201
Rapid determination of aristolochic acid I and II in medicinal plants with high sensitivity by cucurbit[7]uril-modifier capillary zone electrophoresis. Talanta 20080115
Intracellular phospholipase A2 expression and location in human macrophages: influence of synthetic material surface chemistry. Journal of cellular physiology 20080101
Liquid chromatography/mass spectrometry for metabonomics investigation of the biochemical effects induced by aristolochic acid in rats: the use of information-dependent acquisition for biomarker identification. Rapid communications in mass spectrometry : RCM 20080101
TGF-beta1/Smad7 signaling stimulates renal tubulointerstitial fibrosis induced by AAI. Journal of receptor and signal transduction research 20080101
Study on the nitric oxide generating effects from aristolochic acid in vitro. European journal of mass spectrometry (Chichester, England) 20080101
Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation. Toxicological sciences : an official journal of the Society of Toxicology 20071201
[Studies on solid phase extraction method of aristolochic acids and aristololactams in rat urine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer. Carcinogenesis 20071101
New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor. Molecular nutrition & food research 20070901
Pharmacokinetics and nephrotoxicity of aristolochic acid in rabbits. Toxicon : official journal of the International Society on Toxinology 20070801
Toxicology: danger in the diet. Nature 20070712
Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers. Pharmaceutical research 20070701
Selective toxicity of aristolochic acids I and II. Drug metabolism and disposition: the biological fate of chemicals 20070701
Role of mitochondrial permeability transition in human renal tubular epithelial cell death induced by aristolochic acid. Toxicology and applied pharmacology 20070701
Genotoxic effect and nitrative DNA damage in HepG2 cells exposed to aristolochic acid. Mutation research 20070615
In vitro cytotoxicity assay with selected chemicals using human cells to predict target-organ toxicity of liver and kidney. Toxicology in vitro : an international journal published in association with BIBRA 20070601
Role of exposure analysis in solving the mystery of Balkan endemic nephropathy. Croatian medical journal 20070601
Functional characterization of human bitter taste receptors. The Biochemical journal 20070501
Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis. Cancer research 20070501
Liquid chromatography-tandem mass spectrometry analysis of the DNA adducts of aristolochic acids. Journal of the American Society for Mass Spectrometry 20070401
Aristolochic acid-induced cell cycle G1 arrest in human urothelium SV-HUC-1 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070301
Metabolic profiling using combined GC-MS and LC-MS provides a systems understanding of aristolochic acid-induced nephrotoxicity in rat. FEBS letters 20070220
Possible mechanisms explaining the tendency towards interstitial fibrosis in aristolochic acid-induced acute tubular necrosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070201
[Effects of glycyrrihizic acid and prednisone on pathological and ultrastructural changes of kidney in rats with chronic aristolochic acid nephropathy]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070101
Determination of aristolochic acid I in botanicals and dietary supplements potentially contaminated with aristolochic acid I using LC-UV with confirmation by LC/MS: collaborative study. Journal of AOAC International 20070101
DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver. Mutation research 20061201
Effect of aristolochic acid on intracellular calcium concentration and its links with apoptosis in renal tubular cells. Apoptosis : an international journal on programmed cell death 20061201
Establishment of a protocol for the gene expression analysis of laser microdissected rat kidney samples with affymetrix genechips. Toxicology and applied pharmacology 20061115
'Chinese herbal uropathy and nephropathy'? Lancet (London, England) 20061021
[Advances in studies on pharmacokinetics of aristolochic acid I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001
Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences. Mutation research 20060928
Mutations induced by carcinogenic doses of aristolochic acid in kidney of Big Blue transgenic rats. Toxicology letters 20060910
Temporal coding mediates discrimination of 'bitter' taste stimuli by an insect. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060830
[Astragalus and angelica mixture inhibits the renal tubular epithelial cell injury induced by aristolochic-acid I]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20060818
Aristolochic acid I-induced DNA damage and cell cycle arrest in renal tubular epithelial cells in vitro. Archives of toxicology 20060801
A novel trade-off of insect diapause affecting a sequestered chemical defense. Oecologia 20060801
Don't forget pharmacognosy. Lancet (London, England) 20060722
Chinese herbal uropathy and nephropathy. Lancet (London, England) 20060722
NMR-based metabonomic study on the subacute toxicity of aristolochic acid in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701
Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis. Drug metabolism and disposition: the biological fate of chemicals 20060701
[Influence of hypoxia caused by impairment of peritubular capillary on the progression of chronic aristolochic acid nephropathy]. Zhonghua yi xue za zhi 20060606
A sensitive enzyme-linked immunosorbent assay for detecting carcinogenic aristolochic acid in herbal remedies. Journal of agricultural and food chemistry 20060405
Metabonomic study of aristolochic acid-induced nephrotoxicity in rats. Journal of proteome research 20060401
Analysis of nephroloxic and carcinogenic aristolochic acids in Aristolochia plants by capillary electrophoresis with electrochemical detection at a carbon fiber microdisk electrode. Journal of chromatography. A 20060324
Detection of aristolochic acid I, tetrandrine and fangchinoline in medicinal plants by high performance liquid chromatography and liquid chromatography/mass spectrometry. Journal of pharmaceutical and biomedical analysis 20060224
Determination of aristolochic acid in Chinese herbal medicine by capillary electrophoresis with laser-induced fluorescence detection. Journal of chromatography. A 20060210
Chronic renal failure rats are highly sensitive to aristolochic acids, which are nephrotoxic and carcinogenic agents. Cancer letters 20060208
Study on separation of aristolochic acid I and II by micellar electrokinetic capillary chromatography and competition mechanism between SDS and beta-cyclodextrin. Electrophoresis 20060201
[Aristolochic acid nephropathy and acute encephalopathy related to Pleurocybella porrigens (Sugihiratake)]. Nihon rinsho. Japanese journal of clinical medicine 20060201
Induction of urothelial proliferation in rats by aristolochic acid through cell cycle progression via activation of cyclin D1/cdk4 and cyclin E/cdk2. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060101
Aristolochic acid-related nephropathy associated with the popular Chinese herb Xi Xin. Journal of nephrology 20060101
Cytotoxicity of phenanthrenes extracted from Aristolochia contorta in human proximal tubular epithelial cell line. Nephron. Experimental nephrology 20060101
[Determination of aristolochic acid A in Guanxinsuhe preparations by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101
Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products--a consequence of inappropriate nomenclature and imprecise labelling? Clinical toxicology (Philadelphia, Pa.) 20060101
Determination of aristolochic acid in botanicals and dietary supplements by liquid chromatography with ultraviolet detection and by liquid chromatography/mass spectrometry: single laboratory validation confirmation. Journal of AOAC International 20060101
Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats. BMC bioinformatics 20060101
Progesterone primes zona pellucida-induced activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa. Journal of cellular physiology 20051201
The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen. Cancer letters 20051118
Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051101
Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16. Investigative ophthalmology & visual science 20051101
New perspectives on the Chinese herbal nephropathy. Phytotherapy research : PTR 20051101
New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta. Die Pharmazie 20051001
[The therapeutic effects of bosentan and valsartan on renal interstitial fibrosis of chronic aristolochic acid nephropathy]. Zhonghua yi xue za zhi 20050928
An unusual cause of hypokalemic paralysis: aristolochic acid nephropathy with Fanconi syndrome. The American journal of the medical sciences 20050901
GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa. FEBS letters 20050829
[Protective effects of yishen ruanjian power on renal interstitial fribrosis in chronic aristolochic acid induced nephropathy rat model]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050801
[Effect of concocting and extracting on the content of birthwort acid A in imprison wood coherent]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050801
[Methodological studies on selectively removing toxins in Aristolochiae manshuriensis by chinese processing techniques]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801
Stimulation of intracellular Ca2+ elevation in neutrophils by thiol-oxidizing phenylarsine oxide. Biochemical pharmacology 20050415
Interference of arachidonic acid and its metabolites with TNF-alpha release by ochratoxin A from rat liver. Toxicology 20050330
[Key foundational science problem in experimental medicine study of Chinese materia medica: ascertainment of active and toxic constituents from Chinese materia medica]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20050301
Molecular mechanisms of toxicity of important food-borne phytotoxins. Molecular nutrition & food research 20050201
Mast cell infiltration associated with tubulointerstitial fibrosis in chronic Aristolochic Acid Nephropathy. Human & experimental toxicology 20050201
Tumour induction in rats following exposure to short-term high dose aristolochic acid I. Mutagenesis 20050101
Chemopreventive effect of five drugs on renal interstitial fibrosis induced by an aristolochic acid-containing Chinese herb in rats. American journal of nephrology 20050101
Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils. Journal of biomedical science 20050101
[Case of traditional herbal medicine-induced aristolochic acid nephropathy developing to end-stage renal failure]. Nihon Jinzo Gakkai shi 20050101
Application of simplified in vitro screening tests to detect genotoxicity of aristolochic acid. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041201
The influence of hypotonicity on large-conductance calcium-activated potassium channels in human retinal pigment epithelial cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20041201
The blockade of cyclopiazonic acid-induced store-operated Ca2+ entry pathway by YC-1 in neutrophils. Biochemical pharmacology 20041115
Bitter taste receptors for saccharin and acesulfame K. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
[Clinical and pathological analysis on aristolochi acid induced chronic renal impairement in 16 patients]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20041101
Medicinal herbal extracts -- renal friend or foe? Part one: the toxicities of medicinal herbs. Nephrology (Carlton, Vic.) 20041001
Rapid determination of aristolochic acid I and II in Aristolochia plants from different regions by beta-cyclodextrin-modified capillary zone electrophoresis. Journal of chromatography. A 20040917
Adult onset Fanconi syndrome: extensive tubulo-interstitial lesions and glomerulopathy in the early stage of Chinese herbs nephropathy. Clinical and experimental nephrology 20040901
[Antagonistic effect of yishen ruanjian san contained serum against aristolochic acid in antagonizing human renal interstitial fibroblasts]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040901
Herbs and the kidney. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040701
[Studies on pharmacodynamic characteristics of aristolochic acid I in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040701
Aristolochic acid nephropathy: what we know and what we have to do. Nephrology (Carlton, Vic.) 20040601
Fanconi's syndrome and subsequent progressive renal failure caused by a Chinese herb containing aristolochic acid. Nephrology (Carlton, Vic.) 20040601
[Determination of aristolochic acid A in Radix Aristolociae and Herba Asari by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501
DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040401
Transcriptional activation of Igl, the gene for indole formation in Zea mays: a structure-activity study with elicitor-active N-acyl glutamines from insects. Phytochemistry 20040401
Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae. Pest management science 20040401
NMR regulatory analysis: determination and characterization of Chinese-herb aristolochic acids. Die Pharmazie 20040301
Purification of a Class B1 platelet aggregation inhibitor phospholipase A2 from Indian cobra (Naja Naja) venom. Biochimie 20040301
[Cellular mechanism of renal proximal tubular epithelial cell injury induced by aristolochic acid I and aristololactam I]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20040201
Herbal bioactivation: the good, the bad and the ugly. Life sciences 20040109
An easy and rapid method to determine aristolochic acids I and II with high sensitivity. Analytical and bioanalytical chemistry 20040101
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells. British journal of pharmacology 20040101
Hydrolysis of nuclear phospholipids in relation with proliferative state in uterine stromal cells. Biochimie 20040101
p-Bromophenacyl bromide prevents cumene hydroperoxide-induced mitochondrial permeability transition by inhibiting pyridine nucleotide oxidation. Redox report : communications in free radical research 20040101
[Injury in renal proximal tubular epithelial cells induced by aristololactam I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040101
Transgene-derived hepatocyte growth factor attenuates reactive renal fibrosis in aristolochic acid nephrotoxicity. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031201
Analysis of aristolochic acid in nine sources of Xixin, a traditional Chinese medicine, by liquid chromatography/atmospheric pressure chemical ionization/tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20031124
Aristolochic acid nephropathy and the peritoneum: Functional, structural, and molecular studies. Kidney international 20031101
Aristolochic acid, an herbal carcinogen, sold on the Web after FDA alert. The New England journal of medicine 20031016
Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase. Carcinogenesis 20031001
Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells. The Journal of biological chemistry 20030905
The nephrotoxicity of Aristolochia manshuriensis in rats is attributable to its aristolochic acids. Clinical and experimental nephrology 20030901
[Provide against possible trouble--on knowledge, prevention and treatment of adverse drug reactions]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20030501
[A comparative study of manchurian Dutchmanspipe and antibiotics induced acute tubular necrosis in renal cellular biological features]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20030501
Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy. Archives of toxicology 20030401
Zona pellucida induces activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa. Biology of reproduction 20030301
The role of phospholipases A2 in the stimulation of neutrophil motility by cobra venoms. Toxicon : official journal of the International Society on Toxinology 20030301
The importance of a histology-based diagnosis of interstitial nephropathy in two patients with renal insufficiency. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201
Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030101
Aristolochic acid and 'Chinese herbs nephropathy': a review of the evidence to date. Drug safety 20030101
Involvement of phosphatidic acid in both degranulation and oxidative activity in fMet-Leu-Phe stimulated polymorphonuclear leukocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 20021201
Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer? International journal of cancer 20021010
Determination of aristolochic acid I and II in North American species of Asarum and Aristolochia. Die Pharmazie 20021001
Biodegradation of polycarbonate-based polyurethanes by the human monocytes-derived macrophage and U937 cell systems. Journal of biomedical materials research 20020915
Structural basis of phospholipase A2 inhibition for the synthesis of prostaglandins by the plant alkaloid aristolochic acid from a 1.7 A crystal structure. Biochemistry 20020910
An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations. Planta medica 20020901
[Aristolochic acid induced transdifferentiation and apoptosis in human tubular epithelial cells in vitro]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20020901
Contribution of different taste cells and signaling pathways to the discrimination of 'bitter' taste stimuli by an insect. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 20020701
[Influence of long-term use of low dose caulis Aristolochiae manshuriensis on partial nephrectomized rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020601
Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy. Carcinogenesis 20020401
[The phospholipase A2 inhibitor, aristolochic acid, inhibits chloride secretion without altering barrier function]. Gastroenterologia y hepatologia 20020401
Mutagenicity of aristolochic acid in the lambda/lacZ transgenic mouse (MutaMouse). Mutation research 20020325
Chinese herbal nephropathy. Lancet (London, England) 20020302
When is 'aristolochic acid nephropathy' more accurate than 'Chinese herbs nephropathy'? Kidney international 20020301
Aristolochic acid as a causative factor in a case of Chinese herbal nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020301
Aristolochic acid-induced Fanconi's syndrome and nephropathy presenting as hypokalemic paralysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20020301
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma. Journal of neuroscience research 20020215
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats. Journal of the American Society of Nephrology : JASN 20020201
High-performance liquid chromatographic determination for aristolochic acid in medicinal plants and slimming products. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020105
Detecting aristolochic acids in herbal remedies by liquid chromatography/serial mass spectrometry. Rapid communications in mass spectrometry : RCM 20020101
[Renal interstitial fibrosis and urotelial carcinomas after ingestion of a Chinese herb (Aristolochia fangchi)]. Nephrologie 20020101
Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by NADPH : cytochrome P450 reductase form adducts found in DNA of patients with Chinese herbs nephropathy. General physiology and biophysics 20011201
Urothelial malignant disease and Chinese herbal nephropathy. Lancet (London, England) 20011103
Is 'Chinese herbs nephropathy' a prejudicial term? American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Aristolochic acid nephropathy in a Chinese patient: time to abandon the term 'Chinese herbs nephropathy'? American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101
Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells. Kidney international 20011001
Selective adaptation to noxious foods by a herbivorous insect. The Journal of experimental biology 20011001
Progressive interstitial renal fibrosis due to Chinese herbs in a patient with calcinosis Raynaud esophageal sclerodactyly telangiectasia (CREST) syndrome. Internal medicine (Tokyo, Japan) 20011001
[Establishment of model of aristolochic acid-induced chronic renal interstitial fibrosis in rats]. Zhonghua yi xue za zhi 20010925
[The clinical and pathological manifestations of aristolochic acid nephropathy--the report of 58 cases]. Zhonghua yi xue za zhi 20010925
Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. Journal of immunology (Baltimore, Md. : 1950) 20010915
The inhibition of platelet aggregation and blood coagulation by Micropechis ikaheka venom. British journal of haematology 20010901
Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2. Chemical research in toxicology 20010801
Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy. Mutation research 20010725
Focus on 'contrasting effects of cPLA2 on epithelial Na+ transport'. American journal of physiology. Cell physiology 20010701
Contrasting effects of cPLA2 on epithelial Na+ transport. American journal of physiology. Cell physiology 20010701
Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. Reproduction (Cambridge, England) 20010701
Determination of aristolochic acids in medicinal plants (Chinese) prepared medicine using capillary zone electrophoresis. Electrophoresis 20010701
Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation. Mutation research 20010627
From the Food and Drug Administration. JAMA 20010606
Chronic aristolochic acid toxicity in rabbits: a model of Chinese herbs nephropathy? Kidney international 20010601
A peripheral mechanism for behavioral adaptation to specific 'bitter' taste stimuli in an insect. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515
Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria. Free radical biology & medicine 20010415
Outbreak of Chinese herb nephropathy in Japan: are there any differences from Belgium? Internal medicine (Tokyo, Japan) 20010401
Cytosolic phospholipase A2 is required for optimal ATP activation of BK channels in GH(3) cells. The Journal of biological chemistry 20010309
Reversible Fanconi syndrome after ingestion of a Chinese herbal 'remedy' containing aristolochic acid. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010201
Neutrophil-mediated biodegradation of medical implant materials. Journal of cellular physiology 20010101
Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR. Carcinogenesis 20010101
Novel effects of 5,8,11-eicosatriynoic acid, a lipoxygenase inhibitor, on Ca2+ mobilization in Madin Darby canine kidney cells. Pharmacology & toxicology 20010101
[Current status of injury caused by Chinese herbal medicine and its counter measure]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010101

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