A convenient approach for the synthesis of 2,6-diformyl- and 2,6-diacetylpyridines

 

Pavel V. Ivchenko a,⇑, Ilya E. Nifant’ev a,b, Ivan V. Buslov a
Chemistry Department, M.V. Lomonosov Moscow State University, Moscow 119991, Russia
A.V. Topchiev Institute of Petrochemical Synthesis RAS, 29 Leninsky prosp., Moscow 119991, Russia

 

2,6-Diformylpyridine, 2,6-diacetylpyridine and their 4-halo derivatives have often served as convenient starting materials for the synthesis of physiologically active compounds,1 crown-etherlike macrocycles,2 supramolecular coordination complexes,3 metalloenzyme analogues4 and chemosensors.5 Arguably the most important application of these compounds is in the preparation of bis(arylimino)pyridine ligands, [2,6-(ArN@CR)2C5H3N], which impart late transition metals (Fe, Co, Ni and V) with high catalytic activities for ethylene polymerization.6 Bis(imino)pyridyl complexes also catalyse 1,3-butadiene polymerization (Fe, Co),7 oxidation (Fe, Cu),8 hydrogenation (Fe, Co, Ru, Rh),9 hydrosilylation(Fe),9h,i hydrocarboxylation (Fe) 9j and [2+2] cycloaddition (Fe).10

 

To date, pyridine-2,6-dicarbaldehydes have been synthesized by either the oxidation of 2,6-lutidine11 or 2,6-bis(hydroxymethyl)pyridines,3a,12 or by the reduction of 2,6-pyridinedicarboxylic acid chlorides13 and esters14 using relatively expensive composite reagents. In a recent publication, substituted 2,6-diformylpyridine (1) was prepared by the reduction of 2,6-pyridinedicarboxylic acid diamide with diisobutylaluminium hydride;15 a high (75%) yield was achieved using a four fold excess of the reducing agent and by temperature control (70 C, 4 h). LiAlH4, which can reduce aromatic acid amides to aldehydes,16 has not previously been used to prepare compound 1.

 

The most convenient method for the synthesis of 2,6-diacetylpyridine (2) 18a and its 4-substituted analogues18b entails the Claisen condensation of ethyl acetoacetate and dialkyl pyridine-2,6-dicarboxylates; alternative approaches to 2 use 2,6-pyridinedicarboxylic acid dichloride19 or dinitrile.12 2,6-Diacetyl-4-chloropyridine was synthesized from the corresponding 4-chloro-substituted acid dichloride.20 The reaction of amides with MeMgX, which has found use in the synthesis of methyl aryl ketones,21 has not previously been used to prepare 2.

 

Moreover, bis(arylimino)pyridines can be modified at position 4 by direct substitution using alkylmanganese(II) complexes,22 but this method has limited synthetic scope. We hypothesized that the reactions of 2,6-pyridinedicarboxamides with LiAlH4 or Grignard reagents would be suitable for the preparation of pyridines 1, 2 and their 4-substituted analogues. We chose the previously described bis-diethylamide 3 to identify and optimize the reaction conditions.23

 

Aldehyde 1 was prepared in 70–75% yield (Scheme 1) by reduction of 3 in THF24 at 0–5 C for 30 min using LiAlH4 pre-dissolved25 in THF (3/LiAlH4 1:0.7).26 The use of a solution of LiAlH4 was critically important: the addition of 3 to a suspension of LiAlH4 in THF produced a reaction mixture with no more than 30% of 1, even after 16 h of stirring at 20 C followed by hydrolysis. In our opinion, the
poor solubility of the product formed from 3 and LiAlH4 on the surface of the latter hampers the transfer of LiAlH4 to the solution and slows the entire reaction.

 

We established that commercially available MeMgCl in THF27 reacts with 3 at 20 C over 1 hour to give 2 in 80% yield (Scheme 1).28 This reaction can also be performed with MeMgI provided that four equivalents of the Grignard reagent are used. The necessity of a twofold excess of MeMgI in the preparation of 2 can be attributed to the shift of the Schlenk equilibrium towards Me2Mg observed for alkylmagnesium iodides in THF, which is driven by the formation of poorly soluble MgI2(THF)x. 29,30

 

Next, the synthesis of 4-substituted 2,6-diformyl- and 2,6- diacetylpyridines was investigated. The high solubility of amide 3 hampers its isolation and purification. The newly prepared pyrrolidine derivative 4 (Scheme 2) proved less soluble and more reactive towards LiAlH4 and MeMgCl; therefore, we used pyrrolidinyl amides 5–9, synthesized from previously described acid halides to ascertain the applicability of this method to the synthesis of 4-substituted 2,6-diformyl- and 2,6-diacetylpyridines20b,31(Scheme 2).

 

The reactions of diamides 4–7 and 9 with LiAlH4 gave the corresponding 2,6-diformylpyridines (1, 10–13) in satisfactory yields(Table 1). Amide 8 reacted with LiAlH4 to give a complex mixture of the products of pyridine ring reduction.32 The ease of reduction of 9 in the ring can be attributed to the donor properties of the pyrrolidine moiety, which increases the nucleophilicity of the pyridine nitrogen atom. The reactions of 4–9 with MeMgCl proceeded smoothly in all cases, resulting in 2,6-diacetylpyridines 2 and 14–18 in yields of at least 71% (Table 1).

 

In conclusion, we have developed a simple and convenient method for the preparation of 4-functionalized pyridine-2,6-dicarbaldehydes by the direct reduction of the corresponding pyrrolidinyl amides with LiAlH4 pre-dissolved in THF. The use of MeMgCl in the reactions with diamides provided 4-substituted 2,6-diacetylpyridines, which indicates that the enhancement of the reactivity of the customary reactants, achieved here by their dissolution, may be crucial in transforming an evident but unobserved reaction into an efficient synthetic procedure.

 

Supplementary data
Supplementary data (these data include experimental procedures and NMR spectra of new compounds) associated with this article can be found, in the online version, at http://dx.doi.org/10.1016/j.tetlet.2012.11.004.

Angene provides high quality products that are used in Amino Acids Anti-neoplastics Anti-virals Aromatics Carbohydrates Fine Chemicals Herbal Extracts Intermediates and Laboratory Chemicals:

CAS No. 100487-84-1 1H-Indole-1-carboxylic acid, 2,3-dihydro-2-oxo-6-phenyl-, ethyl ester Catalog No.:AG000244 MDL No.: MF:C17H15NO3 MW:281.3059	CAS No. 100488-87-7 Pyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride (1:1) Catalog No.:AG000243 MDL No.: MF:C34H60ClN3O6 MW:642.3097	CAS No. 100489-90-5 1,3-Propanediol, 2-methoxy-, 1-benzoate Catalog No.:AG000242 MDL No.: MF:C11H14O4 MW:210.2265
CAS No. 10049-01-1 Phosphoric acid, bismuth(3+) salt (1:1) Catalog No.:AG00024L MDL No.:MFCD00049721 MF:BiO4P MW:303.9518	CAS No. 10049-05-5 Chromium chloride (CrCl2) Catalog No.:AG00024J MDL No.:MFCD00010947 MF:Cl5Cr3O MW:349.2527	CAS No. 10049-06-6 Titanium chloride (TiCl2) Catalog No.:AG00024I MDL No.: MF:Cl5Ti3+++++ MW:320.8660
CAS No. 10049-07-7 Rhodium chloride (RhCl3) Catalog No.:AG00024H MDL No.:MFCD00011204 MF:Cl15Rh5 MW:1046.3225	CAS No. 10049-08-8 Ruthenium chloride (RuCl3) Catalog No.:AG00024G MDL No.:MFCD00011208 MF:Cl3Ru MW:207.4290	CAS No. 10049-10-2 Chromium fluoride (CrF2) (6CI,7CI,8CI,9CI) Catalog No.:AG00024F MDL No.: MF:Cr3F5O MW:266.9797
CAS No. 10049-11-3 Chromium fluoride (CrF4), (T-4)- (9CI) Catalog No.:AG00024E MDL No.: MF:CrF4 MW:127.9897	CAS No. 10049-12-4 Vanadium fluoride (VF3) (6CI,7CI,8CI,9CI) Catalog No.:AG00024D MDL No.:MFCD00042553 MF:F3V MW:107.9367	CAS No. 10049-14-6 Uranium fluoride (UF4), (T-4)- Catalog No.:AG00024C MDL No.: MF:F4U MW:314.0225
CAS No. 10049-16-8 Vanadium fluoride (VF4) (7CI,8CI,9CI) Catalog No.:AG00024B MDL No.: MF:F5V2+++++ MW:196.8750	CAS No. 10049-17-9 Rhenium fluoride (ReF6), (OC-6-11)- Catalog No.:AG00024A MDL No.:MFCD00042538 MF:F6Re MW:300.1974	CAS No. 10049-21-5 Phosphoric acid, monosodium salt, monohydrate (8CI,9CI) Catalog No.:AG000249 MDL No.:MFCD00149208 MF:H4NaO5P MW:137.9923
CAS No. 10049-24-8 Iridium bromide (IrBr3) Catalog No.:AG000248 MDL No.:MFCD00049466 MF:Br3Ir MW:431.9290	CAS No. 10049-25-9 Chromium bromide (CrBr2) (6CI,7CI,8CI,9CI) Catalog No.:AG000247 MDL No.: MF:Br5Cr3O+++ MW:571.5077	CAS No. 10049-42-0 1-Propanamine, N,N-diethyl-3-(triethoxysilyl)- Catalog No.:AG000246 MDL No.: MF:C13H31NO3Si MW:277.4756
CAS No. 10049-83-9 4-Pyridinemethanol, 3,3'-[dithiobis(methylene)]bis[5-hydroxy-6-methyl-, hydrochloride (1:2) Catalog No.:AG000245 MDL No.:MFCD00057357 MF:C16H22Cl2N2O4S2 MW:441.3929	CAS No. 100490-19-5 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- Catalog No.:AG000241 MDL No.: MF:C19H15F3N4O3 MW:404.3426	CAS No. 100491-37-0 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-(4-chlorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, ethyl ester Catalog No.:AG000257 MDL No.: MF:C17H11Cl2FN2O3 MW:381.1852
CAS No. 100492-04-4 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- Catalog No.:AG000256 MDL No.:MFCD08458410 MF:C15H6ClF3N2O3 MW:354.6679	CAS No. 100493-13-8 2-Oxiranecarboxylic acid, 3-(4-methylphenyl)-, methyl ester, (2R,3S)-rel- Catalog No.:AG000255 MDL No.: MF:C11H12O3 MW:192.2112	CAS No. 100494-47-1 Benzenecarboperoxoic acid, methyl- (9CI) Catalog No.:AG000254 MDL No.: MF:C8H8O3 MW:152.1473
CAS No. 100495-28-1 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis(methylamino)- Catalog No.:AG000253 MDL No.: MF:C16H14N2O4 MW:298.2934	CAS No. 100495-30-5 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis(propylamino)- Catalog No.:AG000252 MDL No.: MF:C20H22N2O4 MW:354.3997	CAS No. 100495-56-5 9,10-Anthracenedione, 1,4-bis(ethylamino)-5,8-dihydroxy- Catalog No.:AG000251 MDL No.: MF:C18H18N2O4 MW:326.3465
CAS No. 100495-94-1 Tetradecanoic acid, 2-hydroxy-, butyl ester Catalog No.:AG000250 MDL No.: MF:C18H36O3 MW:300.4766	CAS No. 100495-98-5 β-D-Glucopyranosiduronic acid, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl Catalog No.:AG00024Z MDL No.: MF:C12H17N3O9 MW:347.2781	CAS No. 1004959-90-3 L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,5-difluoro- Catalog No.:AG00024Q MDL No.:MFCD07372004 MF:C24H19F2NO4 MW:423.4088
CAS No. 100496-41-1 3,5-Dodecadien-1-ol, acetate, (3Z,5E)- (9CI) Catalog No.:AG00024Y MDL No.: MF:C14H24O2 MW:224.3392	CAS No. 100496-44-4 9,11-Tetradecadienal, (9Z,11Z)- Catalog No.:AG00024X MDL No.: MF:C14H24O MW:208.3398	CAS No. 1004972-49-9 3-Pyridazinemethanamine, 6-methyl- Catalog No.:AG00024P MDL No.:MFCD17015869 MF:C6H9N3 MW:123.1558
CAS No. 100498-99-5 Thiazole, 4,5-dihydro-2-[[(2-methylphenyl)methyl]thio]- Catalog No.:AG00024W MDL No.: MF:C11H13NS2 MW:223.3576	CAS No. 100499-06-7 4(1H)-Pyrimidinone, 6-fluoro-2-(methylthio)-5-(trifluoromethyl)- Catalog No.:AG00024V MDL No.: MF:C6H4F4N2OS MW:228.1674	CAS No. 100499-62-5 Formamide, N-(5-methyl-4-isoxazolyl)- Catalog No.:AG00024U MDL No.: MF:C5H6N2O2 MW:126.1133
CAS No. 100499-63-6 Acetamide, N-(5-methyl-4-isoxazolyl)- Catalog No.:AG00024T MDL No.:MFCD09033072 MF:C6H8N2O2 MW:140.1399	CAS No. 100499-66-9 4-Isoxazolamine, 5-methyl-, hydrochloride (1:1) Catalog No.:AG00024S MDL No.:MFCD22421799 MF:C4H7ClN2O MW:134.5642	CAS No. 100499-89-6 Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, 2-oxo-2-(phenylmethoxy)ethyl ester Catalog No.:AG00024R MDL No.: MF:C23H19Cl2NO4 MW:444.3073
CAS No. 1004991-91-6 1H-Pyrazolo[3,4-d]pyriMidine-3-carbonitrile, 4-chloro- Catalog No.:AG00024O MDL No.: MF:C6H2ClN5 MW:179.5666	CAS No. 1004992-44-2 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-ethyl- Catalog No.:AG00024N MDL No.:MFCD18375135 MF:C8H8ClN3 MW:181.6222	CAS No. 1004997-73-2 Benzenemethanamine, 2-amino-5-bromo-, hydrochloride (1:2) Catalog No.:AG00024M MDL No.: MF:C7H11BrCl2N2 MW:273.9856
CAS No. 1005-02-3 2-Pyridinecarboximidic acid, hydrazide Catalog No.:AG000259 MDL No.:MFCD00176950 MF:C6H8N4 MW:136.1545	CAS No. 1005-03-4 2-Pyrimidinecarboximidic acid, hydrazide Catalog No.:AG000258 MDL No.: MF:C5H7N5 MW:137.1426	CAS No. 1005-04-5 4-Morpholineethanamine, β-methyl- Catalog No.:AG00025Y MDL No.:MFCD06446941 MF:C7H16N2O MW:144.2147
CAS No. 1005-05-6 Ethanone, 2-mercapto-1-(1-piperidinyl)- Catalog No.:AG00025X MDL No.:MFCD01011135 MF:C7H13NOS MW:159.2492	CAS No. 1005-06-7 Benzene, 1-chloro-2-(2-chloroethyl)- Catalog No.:AG00025W MDL No.:MFCD11615165 MF:C8H8Cl2 MW:175.0551	CAS No. 1005-12-5 1H-Pyrrole, 2,4-dimethyl-1-propyl- Catalog No.:AG00025V MDL No.: MF:C9H15N MW:137.2221
CAS No. 1005-18-1 Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 3-hydroxy- Catalog No.:AG00025U MDL No.: MF:C8H6O2 MW:134.1320	CAS No. 1005-19-2 Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Catalog No.:AG00025T MDL No.:MFCD06213241 MF:C9H11N MW:133.1903	CAS No. 1005-21-6 Phosphonium, trimethylphenyl-, iodide (1:1) Catalog No.:AG00025S MDL No.: MF:C9H14IP MW:280.0857
CAS No. 1005-24-9 Pyridinium, 3-(aminocarbonyl)-1-methyl-, chloride (1:1) Catalog No.:AG00025R MDL No.:MFCD00060042 MF:C7H9ClN2O MW:172.6122	CAS No. 1005-28-3 5-Thiazolecarboxaldehyde, 2-(dimethylamino)- Catalog No.:AG00025Q MDL No.:MFCD03844445 MF:C6H8N2OS MW:156.2055	CAS No. 1005-31-8 4-Pyridinamine, N,N-dimethyl-, 1-oxide Catalog No.:AG00025P MDL No.:MFCD08273735 MF:C7H10N2O MW:138.1671
CAS No. 1005-37-4 2,4-Pyrimidinediamine, 6-chloro-N4-methyl- Catalog No.:AG00025O MDL No.:MFCD02091108 MF:C5H7ClN4 MW:158.5889	CAS No. 1005-38-5 4-Pyrimidinamine, 6-chloro-2-(methylthio)- Catalog No.:AG00025N MDL No.:MFCD00006088 MF:C5H6ClN3S MW:175.6392	CAS No. 1005-39-6 4,6-Pyrimidinediamine, 2-(methylthio)- Catalog No.:AG00025M MDL No.:MFCD00023241 MF:C5H8N4S MW:156.2088
CAS No. 1005-40-9 Benzene, 1-(ethenyloxy)-3-methyl- Catalog No.:AG00025L MDL No.:MFCD21602807 MF:C9H10O MW:134.1751	CAS No. 1005-51-2 Tricyclo[3.3.2.02,8]deca-3,6,9-triene Catalog No.:AG00025K MDL No.:MFCD09868050 MF:C10H10 MW:130.1864	CAS No. 1005-56-7 Carbonochloridothioic acid, O-phenyl ester Catalog No.:AG00025J MDL No.:MFCD00004920 MF:C7H5ClOS MW:172.6320
CAS No. 1005-62-5 Benzene, 1-(ethenyloxy)-4-methyl- Catalog No.:AG00025I MDL No.: MF:C9H10O MW:134.1751	CAS No. 1005-63-6 Benzenamine, 4-(ethenyloxy)- Catalog No.:AG00025H MDL No.:MFCD02065040 MF:C8H9NO MW:135.1632	CAS No. 1005-66-9 Benzenamine, N-(2-bromoethyl)-, hydrobromide (1:1) Catalog No.:AG00025G MDL No.: MF:C8H11Br2N MW:280.9876
CAS No. 1005-67-0 Morpholine, 4-butyl- Catalog No.:AG00025F MDL No.:MFCD00023401 MF:C8H17NO MW:143.2267	CAS No. 1005-68-1 Cyclopentane, (3-methylbutyl)- Catalog No.:AG00025E MDL No.: MF:C10H20 MW:140.2658	CAS No. 1005-69-2 1,3,2-Dioxaphosphorinane, 2-methoxy-5,5-dimethyl- Catalog No.:AG00025D MDL No.: MF:C6H13O3P MW:164.1394
CAS No. 1005-71-6 Pyridine, 1,2,3,6-tetrahydro-2,2,6,6-tetramethyl-, hydrochloride (1:1) Catalog No.:AG00025C MDL No.:MFCD01691457 MF:C9H18ClN MW:175.6989	CAS No. 1005-73-8 Cyclopentene, 3,3,4,4,5,5-hexafluoro- Catalog No.:AG00025B MDL No.:MFCD03792790 MF:C5H2F6 MW:176.0598	CAS No. 1005-85-2 2-Azaspiro[4.5]decan-1-one Catalog No.:AG00025A MDL No.:MFCD08063849 MF:C9H15NO MW:153.2215
CAS No. 1005-88-5 2,4-Imidazolidinedione, 3-amino-5-ethyl-5-methyl- Catalog No.:AG00026N MDL No.:MFCD04612076 MF:C6H11N3O2 MW:157.1704	CAS No. 1005-93-2 2,6,7-Trioxa-1-phosphabicyclo[2.2.2]octane, 4-ethyl-, 1-oxide Catalog No.:AG00026M MDL No.:MFCD00043597 MF:C6H11O4P MW:178.1229	CAS No. 1005-94-3 7-Oxaspiro[3.5]nonane-6,8-dione Catalog No.:AG00026L MDL No.:MFCD29762582 MF:C8H10O3 MW:154.1632
CAS No. 1005-96-5 1,3,2-Dioxaphosphorinane, 2-methoxy-5,5-dimethyl-, 2-oxide Catalog No.:AG00026K MDL No.: MF:C6H13O4P MW:180.1388	CAS No. 1005-97-6 1,3,2-Dioxaphosphorinane, 2-methoxy-5,5-dimethyl-, 2-sulfide Catalog No.:AG00026J MDL No.: MF:C6H13O3PS MW:196.2044	CAS No. 1005-98-7 1,3,2-Dioxaphosphorinane, 5,5-dimethyl-2-(methylthio)-, 2-oxide Catalog No.:AG00026I MDL No.: MF:C6H13O3PS MW:196.2044
CAS No. 10050-08-5 Bismuthine, tris(2-methylphenyl)- Catalog No.:AG00026H MDL No.:MFCD00123270 MF:C21H21Bi MW:482.3718	CAS No. 10050-12-1 3H-Pyrazol-3-one, 5-amino-2-(4-chlorophenyl)-2,4-dihydro- Catalog No.:AG00026G MDL No.:MFCD00460141 MF:C9H8ClN3O MW:209.6323	CAS No. 10050-57-4 Acetamide, N-(1,3,4-trichloro-7-fluoro-9H-fluoren-2-yl)- Catalog No.:AG00026F MDL No.: MF:C15H9Cl3FNO MW:344.5955
CAS No. 10050-86-9 Benzeneacetonitrile, α-[[4-(dimethylamino)phenyl]imino]- Catalog No.:AG00026E MDL No.: MF:C16H15N3 MW:249.3104	CAS No. 10050-90-5 Ethanone, 2-[(4-hydroxyphenyl)imino]-1-phenyl- Catalog No.:AG00026D MDL No.: MF:C14H11NO2 MW:225.2426	CAS No. 100500-10-5 4,7-Phenanthroline, 3,8-dichloro- Catalog No.:AG00026C MDL No.: MF:C12H6Cl2N2 MW:249.0954
CAS No. 100500-89-8 1-Propanone, 2-hydroxy-1-(1-piperazinyl)- Catalog No.:AG00026B MDL No.:MFCD11213712 MF:C7H14N2O2 MW:158.1983	CAS No. 100500-91-2 2-Propanone, 1-[4-(2-propen-1-yl)-1-piperazinyl]- Catalog No.:AG00026A MDL No.: MF:C10H18N2O MW:182.2627	CAS No. 100500-97-8 2-Propanone, 1-[4-(3-hydroxypropyl)-1-piperazinyl]- Catalog No.:AG000269 MDL No.: MF:C10H20N2O2 MW:200.2780
CAS No. 1005003-43-9 Thiourea, N,N''-(1R)-[1,1'-binaphthalene]-2,2'-diylbis[N'-[3,5-bis(trifluoromethyl)phenyl]- Catalog No.:AG000262 MDL No.: MF: MW:	CAS No. 1005009-91-5 Quinazoline, 4-chloro-6-(6-methoxy-3-pyridinyl)- Catalog No.:AG000261 MDL No.:MFCD20482360 MF:C14H10ClN3O MW:271.7017	CAS No. 1005009-98-2 2-Pyridinamine, N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- Catalog No.:AG000260 MDL No.:MFCD11878220 MF:C12H19BN2O2 MW:234.1025
CAS No. 100501-54-0 Pyrrolo[1,2-a]pyrazin-1(2H)-one, hexahydro-, (R)- (9CI) Catalog No.:AG000268 MDL No.: MF:C7H12N2O MW:140.1830	CAS No. 100501-55-1 1-Piperidinecarboxylic acid, 3-formyl-4-oxo-, 1,1-dimethylethyl ester Catalog No.:AG000267 MDL No.:MFCD06739281 MF:C11H17NO4 MW:227.2570	CAS No. 100501-56-2 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-1-methyl-, 1,1-dimethylethyl ester Catalog No.:AG000266 MDL No.: MF:C12H19N3O2 MW:237.2982
CAS No. 100501-57-3 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 2,4,6,7-tetrahydro-2-methyl-, 1,1-dimethylethyl ester Catalog No.:AG000265 MDL No.:MFCD11044746 MF:C12H19N3O2 MW:237.2982	CAS No. 100501-59-5 2H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-2-methyl- Catalog No.:AG000264 MDL No.:MFCD11858500 MF:C7H11N3 MW:137.1823	CAS No. 100501-62-0 3-Quinolinecarboxylic acid, 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-, ethyl ester Catalog No.:AG000263 MDL No.:MFCD00276022 MF:C14H12F3NO3 MW:299.2452
CAS No. 1005010-02-5 2-Pyridinamine, 5-bromo-N-(2-methoxyethyl)- Catalog No.:AG00025Z MDL No.:MFCD11123673 MF:C8H11BrN2O MW:231.0897	CAS No. 100502-66-7 1,3-Propanediol, 1-nitrate Catalog No.:AG000279 MDL No.: MF:C3H7NO4 MW:121.0920	CAS No. 1005036-23-6 Pyridazine, 3-bromo-6-(2-pyridinyl)- Catalog No.:AG00026Q MDL No.:MFCD12032767 MF:C9H6BrN3 MW:236.0680
CAS No. 1005036-73-6 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)- Catalog No.:AG00026P MDL No.: MF:C17H14F2N2 MW:284.3033	CAS No. 100504-75-4 Benzaldehyde, 3-ethynyl-4-fluoro- Catalog No.:AG000278 MDL No.: MF:C9H5FO MW:148.1338	CAS No. 100504-83-4 1,8-Naphthyridine-3-carboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- Catalog No.:AG000277 MDL No.: MF:C17H19FN4O3 MW:346.3562
CAS No. 100505-13-3 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- Catalog No.:AG000276 MDL No.: MF:C16H19FN4O3 MW:334.3455	CAS No. 100506-87-4 2H-Pyran-4-methanol, 4-(acetyloxy)tetrahydro-, 4-acetate Catalog No.:AG000275 MDL No.: MF:C10H16O5 MW:216.2310	CAS No. 100506-95-4 4H-Thiopyran-4-one, 3,5-dibutyltetrahydro-, trans- (9CI) Catalog No.:AG000274 MDL No.: MF:C13H24OS MW:228.3941
CAS No. 100507-53-7 4H-Thiopyran-4-one, 3,5-diethyltetrahydro-, cis- (9CI) Catalog No.:AG000273 MDL No.: MF:C9H16OS MW:172.2877	CAS No. 100507-77-5 1-Pentene, 3-(ethoxymethylene)-, (3E)- Catalog No.:AG000272 MDL No.: MF:C8H14O MW:126.1962	CAS No. 1005077-74-6 2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester Catalog No.:AG00026O MDL No.:MFCD09040750 MF:C11H20N2O2 MW:212.2887
CAS No. 100508-24-5 Piperazine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-phenyl- Catalog No.:AG000271 MDL No.: MF:C25H26F2N2O MW:408.4835	CAS No. 100508-25-6 Piperazine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-propyl- Catalog No.:AG000270 MDL No.: MF:C22H28F2N2O MW:374.4673	CAS No. 100508-26-7 Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-4-[2-(2-methoxyphenoxy)ethyl]- Catalog No.:AG00026Z MDL No.: MF:C22H28N2O4 MW:384.4687
CAS No. 100508-36-9 Phosphonic acid, [2-(1H-tetrazol-5-yl)ethyl]- (9CI) Catalog No.:AG00026Y MDL No.: MF:C3H7N4O3P MW:178.0864	CAS No. 100508-44-9 Butanoic acid, 3-methyl-, 6,10,13-trimethyltetradecyl ester Catalog No.:AG00026X MDL No.: MF:C22H44O2 MW:340.5836	CAS No. 100508-45-0 1-Tetradecanol, 6,10,13-trimethyl- Catalog No.:AG00026W MDL No.: MF:C17H36O MW:256.4671
CAS No. 100508-54-1 3-Hexene-2-thione, 4-amino-1,1,1-trifluoro-5,5-dimethyl- Catalog No.:AG00026V MDL No.: MF:C8H12F3NS MW:211.2478	CAS No. 100508-56-3 1,3,5-Triazine, 2-(2-fluoro-2,2-dinitroethoxy)-4,6-dimethoxy- Catalog No.:AG00026U MDL No.: MF:C7H8FN5O7 MW:293.1661	CAS No. 100508-57-4 1,3,5-Triazine, 2,4-bis(2-fluoro-2,2-dinitroethoxy)-6-methoxy- Catalog No.:AG00026T MDL No.: MF:C8H7F2N7O11 MW:415.1783
CAS No. 100508-68-7 Benzothiazolium, 3-[2-oxo-2-(2-propen-1-yloxy)ethyl]-, bromide (1:1) Catalog No.:AG00026S MDL No.: MF:C12H12BrNO2S MW:314.1982	CAS No. 100509-05-5 Phosphoric acid, 4-(acetylamino)phenyl dimethyl ester Catalog No.:AG00026R MDL No.: MF:C10H14NO5P MW:259.1956	CAS No. 10051-06-6 Guanidine, N,N,N',N',N''-pentafluoro- Catalog No.:AG00027C MDL No.: MF:CF5N3 MW:149.0228
CAS No. 10051-44-2 Hexanoic acid, sodium salt (1:1) Catalog No.:AG00027B MDL No.:MFCD00059056 MF:C6H11NaO2 MW:138.1401	CAS No. 10051-45-3 Heptanoic acid, sodium salt (1:1) Catalog No.:AG00027A MDL No.:MFCD00070499 MF:C7H13NaO2 MW:152.1667	CAS No. 100510-64-3 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-6-nitro- Catalog No.:AG00027Z MDL No.:MFCD13191794 MF:C10H10N2O3 MW:206.1980
CAS No. 100510-65-4 2H-Indol-2-one, 6-amino-1,3-dihydro-3,3-dimethyl- Catalog No.:AG00027Y MDL No.:MFCD11053509 MF:C10H12N2O MW:176.2151	CAS No. 100510-96-1 Acetamide, N-(2,3-dihydro-3,3-dimethyl-6-nitro-2-oxo-1H-indol-5-yl)- Catalog No.:AG00027X MDL No.: MF:C12H13N3O4 MW:263.2493	CAS No. 100510-99-4 2H-Indol-2-one, 5-amino-3,3-diethyl-1,3-dihydro- Catalog No.:AG00027W MDL No.: MF:C12H16N2O MW:204.2682
CAS No. 100511-00-0 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-5-nitro- Catalog No.:AG00027V MDL No.:MFCD13191795 MF:C10H10N2O3 MW:206.1980	CAS No. 100511-49-7 Benzenebutanamide, 4-[(aminoiminomethyl)amino]-N-[(1S)-2-[[4-[(3-aminopropyl)amino]butyl]amino]-1-(hydroxymethyl)-2-oxoethyl]- Catalog No.:AG00027U MDL No.: MF:C21H37N7O3 MW:435.5636	CAS No. 100511-78-2 Benzenepropanoic acid, 4-(aminomethyl)-, methyl ester Catalog No.:AG00027T MDL No.:MFCD08060494 MF:C11H15NO2 MW:193.2423
CAS No. 100511-83-9 Benzenepropanoic acid, 3-(aminomethyl)-, methyl ester Catalog No.:AG00027S MDL No.: MF:C11H15NO2 MW:193.2423	CAS No. 1005134-08-6 4,7-Methano-2H-isoindole-2-acetic acid, 1,3,3a,4,7,7a-hexahydro-3a-methyl-1,3-dioxo- Catalog No.:AG00027E MDL No.:MFCD05990278 MF:C12H13NO4 MW:235.2359	CAS No. 100515-02-4 2-Cyclohexen-1-one, 3-benzoyl- Catalog No.:AG00027R MDL No.: MF:C13H12O2 MW:200.2332
CAS No. 100515-03-5 2,4-Pyrimidinediamine, 5-[(3,5-diethoxyphenyl)methyl]- Catalog No.:AG00027Q MDL No.: MF:C15H20N4O2 MW:288.3449	CAS No. 100515-04-6 2,4-Pyrimidinediamine, 5-[(3,5-dimethylphenyl)methyl]- Catalog No.:AG00027P MDL No.: MF:C13H16N4 MW:228.2929	CAS No. 100515-17-1 Benzene, 1-(dimethoxymethyl)-4-(methylthio)- Catalog No.:AG00027O MDL No.: MF:C10H14O2S MW:198.2820
CAS No. 100515-66-0 Diazene, 1,2-bis(dicyclopropylmethyl)-, (1E)- Catalog No.:AG00027N MDL No.: MF:C14H22N2 MW:218.3379	CAS No. 1005154-25-5 Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(2-propen-1-ylamino)carbonyl]- Catalog No.:AG00027D MDL No.:MFCD09834081 MF:C12H17NO3 MW:223.2683	CAS No. 100516-18-5 Benzo[k]fluoranthen-3-ol Catalog No.:AG00027M MDL No.: MF:C20H12O MW:268.3087
CAS No. 100516-54-9 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2R,3S)- Catalog No.:AG00027L MDL No.:MFCD00074958 MF:C24H21NO4 MW:387.4278	CAS No. 100516-61-8 Benzene, 1,2,3,4,5,6-hexaethynyl- Catalog No.:AG00027K MDL No.: MF:C18H6 MW:222.2402	CAS No. 100516-62-9 Benzene, 1,2,3,4,5,6-hexakis[2-(trimethylsilyl)ethynyl]- Catalog No.:AG00027J MDL No.: MF:C36H54Si6 MW:655.3270
CAS No. 100516-64-1 Zirconium, dichloro[(dimethylsilylene)bis[(1,2,3,4,5-η)-2,3,4,5-tetramethyl-2,4-cyclopentadien-1-ylidene]]- Catalog No.:AG00027I MDL No.: MF: MW:	CAS No. 100516-71-0 2-Thiazolecarbonitrile, 5-methyl- Catalog No.:AG00027H MDL No.:MFCD11109818 MF:C5H4N2S MW:124.1637	CAS No. 100516-76-5 2-Thiazolecarboxylic acid, 4-methyl-, hydrazide Catalog No.:AG00027G MDL No.: MF:C5H7N3OS MW:157.1936
CAS No. 100516-82-3 Thiophene, 2,3-dibromotetrahydro-2-methyl-, 1,1-dioxide Catalog No.:AG00027F MDL No.: MF:C5H8Br2O2S MW:291.9888	CAS No. 100516-85-6 2-Propanol, 1-chloro-3-iodo-, acetate (6CI,9CI) Catalog No.:AG00028L MDL No.: MF:C5H8ClIO2 MW:262.4733	CAS No. 100516-88-9 Quinolin-6-ylmethanol Catalog No.:AG00028K MDL No.:MFCD03789621 MF:C10H9NO MW:159.1846
CAS No. 100516-90-3 2,6,7(1H)-Pteridinetrione, 3,5-dihydro- Catalog No.:AG00028J MDL No.: MF:C6H4N4O3 MW:180.1210	CAS No. 100516-92-5 6,7-Pteridinedione, 2-amino-5,8-dihydro- Catalog No.:AG00028I MDL No.:MFCD22196065 MF:C6H5N5O2 MW:179.1362	CAS No. 100516-95-8 2-Propen-1-amine, 2-chloro-, hydrochloride (9CI) Catalog No.:AG00028H MDL No.:MFCD19686253 MF:C3H7Cl2N MW:128.0004
CAS No. 100516-98-1 2-Thiazolecarbonitrile, 4-methyl- Catalog No.:AG00028G MDL No.:MFCD08276856 MF:C5H4N2S MW:124.1637	CAS No. 1005161-88-5 5-Pyrimidinecarboxylic acid, 2-(methylthio)-4-(2-phenylethynyl)-, ethyl ester Catalog No.:AG000287 MDL No.: MF:C16H14N2O2S MW:298.3596	CAS No. 100517-03-1 4-Thiazolecarboxylic acid, 5-methyl-, hydrazide Catalog No.:AG00028F MDL No.: MF:C5H7N3OS MW:157.1936
CAS No. 100517-42-8 3-Quinolinecarboxaldehyde, 4-chloro-1,2-dihydro-2-oxo- Catalog No.:AG00028E MDL No.:MFCD05665609 MF:C10H6ClNO2 MW:207.6131	CAS No. 100517-70-2 5-Pyrimidinecarboxylic acid, 4-methyl-2-phenyl-, hydrazide Catalog No.:AG00028D MDL No.:MFCD03086119 MF:C12H12N4O MW:228.2499	CAS No. 100517-91-7 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-5-(2-phenyldiazenyl)- Catalog No.:AG00028C MDL No.: MF:C12H12N4O3 MW:260.2487
CAS No. 100518-55-6 Phenol, compd. with benzene (1:1) Catalog No.:AG00028B MDL No.: MF:C12H12O MW:172.2231	CAS No. 100518-70-5 Hydroperoxide, 1-(2-naphthalenyl)ethyl Catalog No.:AG00028A MDL No.: MF:C12H12O2 MW:188.2225	CAS No. 1005187-65-4 1,3,8-Triazaspiro[4.5]decane-1,3,8-tricarboxylic acid, 2,4-dioxo-, 1,3-bis(1,1-dimethylethyl) 8-(phenylmethyl) ester Catalog No.:AG000286 MDL No.: MF:C25H33N3O8 MW:503.5448
CAS No. 100519-34-4 Benzeneacetic acid, 4-(acetyloxy)-α-oxo-, ethyl ester Catalog No.:AG000289 MDL No.: MF:C12H12O5 MW:236.2207	CAS No. 1005196-13-3 Thiazole, 2-(4-fluorophenyl)- Catalog No.:AG000285 MDL No.:MFCD12033576 MF:C9H6FNS MW:179.2140	CAS No. 1005196-61-1 Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-chloro-, methyl ester Catalog No.:AG000284 MDL No.:MFCD11616515 MF:C8H6ClN3O2 MW:211.6051
CAS No. 10052-09-2 3-Pyridinecarboxamide, N,N-dipropyl- Catalog No.:AG00028O MDL No.: MF:C12H18N2O MW:206.2841	CAS No. 10052-47-8 Ethanaminium, N,N-diethyl-N-methyl-, chloride (1:1) Catalog No.:AG00028N MDL No.:MFCD00059972 MF:C7H18ClN MW:151.6775	CAS No. 10052-96-7 Phosphine oxide, phenyl- Catalog No.:AG00028M MDL No.: MF:C6H7OP MW:126.0929
CAS No. 100520-15-8 1,3-Cyclohexadiene-1-carboxylic acid, 4,6,6-trimethyl-, ethyl ester Catalog No.:AG000288 MDL No.: MF:C12H18O2 MW:194.2701	CAS No. 1005201-59-1 Borate(1-), trifluoro[(1E)-3-phenyl-1-propen-1-yl]-, potassium (1:1), (T-4)- Catalog No.:AG000282 MDL No.: MF: MW:	CAS No. 1005205-25-3 1H-Indazole-5-carboxylic acid, hydrazide Catalog No.:AG000281 MDL No.:MFCD11506092 MF:C8H8N4O MW:176.1753
CAS No. 1005206-16-5 7H-Pyrrolo[2,3-d]pyrimidine-4-carbonitrile Catalog No.:AG000280 MDL No.:MFCD17015948 MF:C7H4N4 MW:144.1335	CAS No. 1005206-17-6 7H-Pyrrolo[2,3-d]pyrimidine-4-carboxylic acid Catalog No.:AG00028W MDL No.:MFCD13193623 MF:C7H5N3O2 MW:163.1335	CAS No. 1005206-25-6 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[4-[(trifluoromethyl)thio]phenyl]- Catalog No.:AG00028V MDL No.:MFCD11042448 MF:C13H16BF3O2S MW:304.1361
CAS No. 1005207-32-8 Boronic acid, B-[4-[(phenylmethyl)thio]phenyl]- Catalog No.:AG00028U MDL No.:MFCD06801692 MF:C13H13BO2S MW:244.1171	CAS No. 1005209-40-4 Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 6-bromo-, methyl ester Catalog No.:AG00028T MDL No.:MFCD16890139 MF:C8H6BrN3O2 MW:256.0561	CAS No. 1005209-42-6 Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 6-bromo-, ethyl ester Catalog No.:AG00028S MDL No.:MFCD11616111 MF:C9H8BrN3O2 MW:270.0827
CAS No. 1005209-44-8 Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 6-chloro-, ethyl ester Catalog No.:AG00028R MDL No.:MFCD11616110 MF:C9H8ClN3O2 MW:225.6317	CAS No. 100521-18-4 1,3-Dioxolane, 2,2'-(1,4-butanediyl)bis[4-methylene- Catalog No.:AG00029D MDL No.: MF:C12H18O4 MW:226.2689	CAS No. 1005212-02-1 1H-Oxireno[1,10a]phenanthro[3,2-b]furan-9(7aH)-one, 1,3-bis(acetyloxy)-2,3,4,4a,5,6,10a,11,11a,11b-decahydro-4,4,8,11b-tetramethyl-, (1S,3S,4aR,6aS,7aR,10aR,11aS,11bR)- Catalog No.:AG00028Q MDL No.: MF: MW:
CAS No. 1005212-22-5 1H-1-Silaindene, 2,3-dihydro-1-methyl- Catalog No.:AG00028P MDL No.: MF:C9H12Si MW:148.2771	CAS No. 100523-79-3 Hexanoic acid, 5-mercapto- Catalog No.:AG00029C MDL No.: MF:C6H12O2S MW:148.2233	CAS No. 100523-83-9 Pyridine, 4-bromo-2-iodo- Catalog No.:AG00029B MDL No.:MFCD07368063 MF:C5H3BrIN MW:283.8925
CAS No. 100523-84-0 3-Thiophenecarboxylic acid, 5-bromo- Catalog No.:AG00029A MDL No.:MFCD08695074 MF:C5H3BrO2S MW:207.0451	CAS No. 100523-85-1 Benzoic acid, 4-ethyl-3-hydroxy- Catalog No.:AG000299 MDL No.:MFCD08460110 MF:C9H10O3 MW:166.1739	CAS No. 100523-96-4 Pyridine, 2-bromo-4-iodo- Catalog No.:AG000298 MDL No.:MFCD03085768 MF:C5H3BrIN MW:283.8925
CAS No. 100524-07-0 Benzenecarboximidamide, 3-amino-N-hydroxy- Catalog No.:AG000297 MDL No.:MFCD08061150 MF:C7H9N3O MW:151.1659	CAS No. 100524-19-4 1,2,4-Triazine-6-propanoic acid, 2,5-dihydro-3-(methylthio)-5-oxo- Catalog No.:AG000296 MDL No.: MF:C7H9N3O3S MW:215.2297	CAS No. 100524-24-1 1H-Pyrazolo[3,4-d]pyrimidine-1-ethanol, 4-amino- Catalog No.:AG000295 MDL No.:MFCD00128326 MF:C7H9N5O MW:179.1793
CAS No. 100524-26-3 Hydrazinecarboximidamide, N-nitro-2-phenyl- (9CI) Catalog No.:AG000294 MDL No.: MF:C7H9N5O2 MW:195.1787	CAS No. 100524-52-5 Pseudourea, 2,2'-(iminodiethylene)bis[2-thio-, trihydrobromide (6CI) Catalog No.:AG000293 MDL No.: MF:C6H18Br3N5S2 MW:464.0826	CAS No. 100525-32-4 Phosphonamidic acid, N,N-diethyl-P-phenyl-, ethyl ester Catalog No.:AG000292 MDL No.: MF:C12H20NO2P MW:241.2665
CAS No. 100527-20-6 Phenanthrene, 3,6-dinitro- Catalog No.:AG000291 MDL No.: MF:C14H8N2O4 MW:268.2243	CAS No. 100527-31-9 Ethanedione, bis(4-hydroxy-3-nitrophenyl)- (9CI) Catalog No.:AG000290 MDL No.: MF:C14H8N2O8 MW:332.2219	CAS No. 100527-50-2 4(3H)-Quinazolinethione, 2-(4-bromophenyl)- Catalog No.:AG00028Z MDL No.:MFCD06336121 MF:C14H9BrN2S MW:317.2037
CAS No. 100527-91-1 Propanenitrile, 3-(dipentylamino)- Catalog No.:AG00028Y MDL No.: MF:C13H26N2 MW:210.3589	CAS No. 100528-00-5 Carbamimidic acid, N,N'-bis(1-methylethyl)-, cyclohexyl ester Catalog No.:AG00028X MDL No.: MF:C13H26N2O MW:226.3583	CAS No. 100528-25-4 Hexanoic acid, 6-[(6-aminohexyl)amino]-6-oxo-, methyl ester Catalog No.:AG0002A2 MDL No.: MF:C13H26N2O3 MW:258.3571
CAS No. 100528-70-9 2H-Pyran, 2-[(2-ethylhexyl)oxy]tetrahydro- Catalog No.:AG0002A1 MDL No.: MF:C13H26O2 MW:214.3443	CAS No. 100528-78-7 Undecanoic acid, 11-(methylthio)-, methyl ester Catalog No.:AG0002A0 MDL No.: MF:C13H26O2S MW:246.4093	CAS No. 1005291-43-9 4-Pyridinecarboxaldehyde, 2-bromo-5-fluoro- Catalog No.:AG00029S MDL No.:MFCD09800558 MF:C6H3BrFNO MW:203.9965
CAS No. 1005294-11-0 BENZAMIDE, N-[1-(2-FURANYLCARBONYL)-1,2,3,4-TETRAHYDRO-7-QUINOLINYL]-3,5-DIMETHOXY- Catalog No.:AG00029R MDL No.: MF:C23H22N2O5 MW:406.4312	CAS No. 1005294-19-8 BENZAMIDE, 3,5-DIMETHOXY-N-[1,2,3,4-TETRAHYDRO-1-(2-THIENYLCARBONYL)-7-QUINOLINYL]- Catalog No.:AG00029Q MDL No.: MF:C23H22N2O4S MW:422.4968	CAS No. 1005294-21-2 BENZENEPROPANAMIDE, N-[1,2,3,4-TETRAHYDRO-1-(2-THIENYLCARBONYL)-7-QUINOLINYL]- Catalog No.:AG00029P MDL No.: MF:C23H22N2O2S MW:390.4980
CAS No. 1005294-23-4 BENZAMIDE, 4-METHOXY-N-[1,2,3,4-TETRAHYDRO-1-(2-METHYL-1-OXOPROPYL)-7-QUINOLINYL]- Catalog No.:AG00029O MDL No.: MF:C21H24N2O3 MW:352.4269	CAS No. 100530-42-5 Acetic acid, 2-[(4-ethoxyphenyl)amino]-2-oxo- Catalog No.:AG00029Z MDL No.: MF:C10H11NO4 MW:209.1986	CAS No. 1005301-95-0 BENZENESULFONAMIDE, N-[1-(2-FURANYLCARBONYL)-1,2,3,4-TETRAHYDRO-7-QUINOLINYL]-2,4-DIMETHYL- Catalog No.:AG00029N MDL No.: MF:C22H22N2O4S MW:410.4861
CAS No. 100531-21-3 2-Oxazolamine, N-(decahydro-1-naphthalenyl)-4,5-dihydro- Catalog No.:AG00029Y MDL No.: MF:C13H22N2O MW:222.3266	CAS No. 1005326-26-0 Ethyl 3-amino-5-methyl-1H-pyrrole-2-carboxylate Catalog No.:AG00029M MDL No.:MFCD11878015 MF:C8H12N2O2 MW:168.1931	CAS No. 1005328-52-8 2-Benzofuranacetic acid, 5-chloro-, methyl ester Catalog No.:AG00029L MDL No.:MFCD22372641 MF:C11H9ClO3 MW:224.6404
CAS No. 100533-08-2 Benzenemethanol, α,α-diethyl-2,3-dimethoxy- Catalog No.:AG00029X MDL No.: MF:C13H20O3 MW:224.2961	CAS No. 1005332-77-3 3-Quinolinecarboxylic acid, 6-bromo-1,2-dihydro-4-hydroxy-2-oxo-, methyl ester Catalog No.:AG00029K MDL No.:MFCD14282089 MF:C11H8BrNO4 MW:298.0895	CAS No. 1005342-46-0 Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)- Catalog No.:AG00029J MDL No.:MFCD23160049 MF:C26H33FN4O3S MW:500.6286
CAS No. 1005342-78-8 1-Pyrrolidinecarboxylic acid, 2-[4-(4-fluorobenzoyl)-2-thiazolyl]-, 1,1-dimethylethyl ester, (2S)- Catalog No.:AG00029I MDL No.: MF:C19H21FN2O3S MW:376.4450	CAS No. 1005342-94-8 2-Pyridinecarboxamide, 4-bromo-N-methoxy-N-methyl- Catalog No.:AG00029H MDL No.: MF:C8H9BrN2O2 MW:245.0733	CAS No. 1005346-96-2 Boronic acid, B-(2-formyl-4,5-dimethoxyphenyl)- Catalog No.:AG00029G MDL No.:MFCD16660278 MF:C9H11BO5 MW:209.9916
CAS No. 1005349-12-1 2-Pyrazinamine, 3-[2-(trimethylsilyl)ethynyl]- Catalog No.:AG00029F MDL No.: MF:C9H13N3Si MW:191.3051	CAS No. 1005349-13-2 2-Pyrazinamine, 3-ethynyl- Catalog No.:AG00029E MDL No.:MFCD09999143 MF:C6H5N3 MW:119.1240	CAS No. 100535-50-0 Heptanoic acid, 2-amino-3-butyl- Catalog No.:AG00029W MDL No.: MF:C11H23NO2 MW:201.3058
CAS No. 100535-85-1 Piperazine, 1-methyl-4-[(1-methyl-2-pyrrolidinyl)methyl]- Catalog No.:AG00029V MDL No.: MF:C11H23N3 MW:197.3204	CAS No. 100536-94-5 1-Undecanol, 2,11-dimercapto- Catalog No.:AG00029U MDL No.: MF:C11H24OS2 MW:236.4377	CAS No. 100536-95-6 1,4-Butanediol, 2-heptyl- Catalog No.:AG00029T MDL No.: MF:C11H24O2 MW:188.3071
CAS No. 100537-09-5 2-Heptanol, 1,1-diethoxy- Catalog No.:AG0002AK MDL No.: MF:C11H24O3 MW:204.3065	CAS No. 100537-27-7 Isoquinoline, 1-(4-pyridinyl)- Catalog No.:AG0002AJ MDL No.: MF:C14H10N2 MW:206.2426	CAS No. 100537-30-2 Phthalazine, 1-phenoxy- Catalog No.:AG0002AI MDL No.: MF:C14H10N2O MW:222.2420
CAS No. 100537-34-6 1,2,4-Thiadiazolidin-5-one, 2,4-diphenyl-3-thioxo- Catalog No.:AG0002AH MDL No.: MF:C14H10N2OS2 MW:286.3720	CAS No. 100537-44-8 1,2-Benzisothiazol-3(2H)-one, 2-[[(2-hydroxyphenyl)methylene]amino]- Catalog No.:AG0002AG MDL No.: MF:C14H10N2O2S MW:270.3064	CAS No. 100537-55-1 1H-Pyrazole-3-carboxylic acid, 5-(2-furanyl)-1-phenyl- Catalog No.:AG0002AF MDL No.:MFCD06245333 MF:C14H10N2O3 MW:254.2408
CAS No. 100538-35-0 [1,1'-Biphenyl]-2-carboxylic acid, 3'-formyl- Catalog No.:AG0002AE MDL No.:MFCD04039067 MF:C14H10O3 MW:226.2274	CAS No. 100538-37-2 1-Dibenzofuranol, 1-acetate Catalog No.:AG0002AD MDL No.: MF:C14H10O3 MW:226.2274	CAS No. 100538-93-0 3-Azabicyclo[3.3.1]nonane, 3-(3-methylbutyl)-, hydrobromide (1:1) Catalog No.:AG0002AC MDL No.: MF:C13H26BrN MW:276.2562
CAS No. 1005397-64-7 1-Piperidinecarboxylic acid, 2,6-dimethyl-4-oxo-, 1,1-dimethylethyl ester, (2R,6S)-rel- Catalog No.:AG0002A4 MDL No.:MFCD19230167 MF:C12H21NO3 MW:227.3000	CAS No. 1005397-65-8 1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester Catalog No.:AG0002A3 MDL No.: MF:C18H32BNO4 MW:337.2620	CAS No. 10054-09-8 2-Octene, 2-methyl-6-methylene- Catalog No.:AG0002AQ MDL No.: MF:C10H18 MW:138.2499
CAS No. 10054-20-3 3-Pyrrolidinecarboxylic acid, 1-octadecyl-5-oxo- Catalog No.:AG0002AP MDL No.: MF:C23H43NO3 MW:381.5924	CAS No. 10054-21-4 3-Pyrrolidinecarboxylic acid, 1-dodecyl-5-oxo- Catalog No.:AG0002AO MDL No.:MFCD01688135 MF:C17H31NO3 MW:297.4329	CAS No. 10054-22-5 3-Pyrrolidinecarboxylic acid, 5-oxo-1-tetradecyl- Catalog No.:AG0002AN MDL No.: MF:C19H35NO3 MW:325.4861
CAS No. 10054-74-7 2,5-Cyclooctadien-1-ol Catalog No.:AG0002AM MDL No.: MF:C8H12O MW:124.1803	CAS No. 100540-61-2 4(3H)-Quinazolinone, 6,8-diiodo- Catalog No.:AG0002AB MDL No.: MF:C8H4I2N2O MW:397.9391	CAS No. 100540-89-4 9H-Xanthene-9-carboxylic acid, 2,7-dibromo- Catalog No.:AG0002AA MDL No.: MF:C14H8Br2O3 MW:384.0195
CAS No. 100540-90-7 Benzoic acid, 2,2'-dithiobis[5-bromo- Catalog No.:AG0002A9 MDL No.: MF:C14H8Br2O4S2 MW:464.1489	CAS No. 100541-43-3 1,3,4-Oxadiazole, 2,5-bis(4-iodophenyl)- Catalog No.:AG0002A8 MDL No.: MF:C14H8I2N2O MW:474.0351	CAS No. 100542-74-3 Phenol, 4-chloro-2-[[(4-methoxyphenyl)imino]methyl]- Catalog No.:AG0002A7 MDL No.: MF:C14H12ClNO2 MW:261.7036
CAS No. 100543-12-2 1,3-Propanediol, 2-(hydroxymethyl)-2-(octylamino)- Catalog No.:AG0002A6 MDL No.: MF:C12H27NO3 MW:233.3477	CAS No. 100543-40-6 Phosphonic acid, (1-methylpropyl)-, dibutyl ester (9CI) Catalog No.:AG0002A5 MDL No.: MF:C12H27O3P MW:250.3147	CAS No. 1005450-55-4 Benzenepropanamide, N-[(1R)-1-(1-naphthalenyl)ethyl]-3-(trifluoromethyl)- Catalog No.:AG0002AY MDL No.:MFCD18207041 MF:C22H20F3NO MW:371.3955
CAS No. 1005458-13-8 Methanone, 1H-indol-6-yl[4-(1-methylethyl)-1-piperazinyl]- Catalog No.:AG0002AX MDL No.: MF:C16H21N3O MW:271.3574	CAS No. 1005460-15-0 Benzenecarboximidamide, 2,4,6-trifluoro- Catalog No.:AG0002AW MDL No.:MFCD09745451 MF:C7H5F3N2 MW:174.1232	CAS No. 1005474-88-3 2-Pyridinecarboxylic acid, 5-fluoro-6-methyl- Catalog No.:AG0002AV MDL No.:MFCD11040267 MF:C7H6FNO2 MW:155.1264
CAS No. 1005498-91-8 2H-Pyran-4-amine, tetrahydro-, acetate (1:1) Catalog No.:AG0002AU MDL No.:MFCD08445669 MF:C7H15NO3 MW:161.1989	CAS No. 1005500-75-3 Benzenesulfonamide, N-ethynyl-N,4-dimethyl- Catalog No.:AG0002AT MDL No.:MFCD30861485 MF:C10H11NO2S MW:209.2648	CAS No. 1005504-62-0 2,4-Quinazolinediamine, 5-[[1-[(2,6-dichlorophenyl)methyl]-4-piperidinyl]methoxy]- Catalog No.:AG0002AS MDL No.: MF:C21H23Cl2N5O MW:432.3462
CAS No. 100551-69-7 Thiourea, N-(3,3-diethoxypropyl)-N'-β-D-ribofuranosyl- Catalog No.:AG0002B1 MDL No.: MF:C13H26N2O6S MW:338.4203	CAS No. 1005515-26-3 2-Pyridinemethanamine, 4-(trifluoromethyl)-, hydrochloride (1:1) Catalog No.:AG0002AR MDL No.:MFCD04117763 MF:C7H8ClF3N2 MW:212.6000	CAS No. 100553-53-5 Guanidine, N-butoxy-N'-(4,6-dimethyl-2-pyrimidinyl)- Catalog No.:AG0002B0 MDL No.: MF:C11H19N5O MW:237.3015
CAS No. 100553-55-7 Pyrimidine, hexahydro-2-(nitromethylene)-1-(4-pyridinylmethyl)- Catalog No.:AG0002AZ MDL No.: MF:C11H14N4O2 MW:234.2545