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94-41-7 | CHALCONE
CAS No: 94-41-7 Catalog No: AG003ORQ MDL No:MFCD00003082
Product Description
Catalog Number:
AG003ORQ
Chemical Name:
CHALCONE
CAS Number:
94-41-7
Molecular Formula:
C15H12O
Molecular Weight:
208.2552
MDL Number:
MFCD00003082
IUPAC Name:
(E)-1,3-diphenylprop-2-en-1-one
InChI:
InChI=1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
InChI Key:
DQFBYFPFKXHELB-VAWYXSNFSA-N
SMILES:
O=C(c1ccccc1)C=Cc1ccccc1
UNII:
5S5A2Q39HX
Properties
Complexity:
242
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1
Exact Mass:
208.089g/mol
Formal Charge:
0
Heavy Atom Count:
16
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
208.26g/mol
Monoisotopic Mass:
208.089g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
17.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.1
Literature
| Title | Journal |
|---|---|
| Azide-alkyne cycloaddition en route to 4-aminoquinoline-ferrocenylchalcone conjugates: synthesis and anti-TB evaluation. | Future medicinal chemistry 20171001 |
| QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity. | European journal of medicinal chemistry 20170908 |
| Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170801 |
| 3'-Geranyl-mono-substituted chalcone Xanthoangelovl induces apoptosis in human leukemia K562 cells via activation of mitochondrial pathway. | Chemico-biological interactions 20170105 |
| MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis. | British journal of pharmacology 20150901 |
| Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. | Toxicological sciences : an official journal of the Society of Toxicology 20150201 |
| Design, synthesis and exploring the quantitative structure-activity relationship of some antioxidant flavonoid analogues. | Bioorganic & medicinal chemistry letters 20141101 |
| Hydroxysafflor yellow A of Carthamus tinctorius attenuates lung injury of aged rats exposed to gasoline engine exhaust by down-regulating platelet activation. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20140215 |
| Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides. | Bioorganic & medicinal chemistry 20140201 |
| Antifungal dimeric chalcone derivative kamalachalcone E from Mallotus philippinensis. | Natural product research 20140101 |
| Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130801 |
| 2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells. | Chemico-biological interactions 20130525 |
| Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix. | Journal of ethnopharmacology 20130109 |
| Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. | Chemical research in toxicology 20121119 |
| Synthesis and biological evaluation of chalcone derivatives (mini review). | Mini reviews in medicinal chemistry 20121101 |
| Development of a stability-indicating LC method for determination of a synthetic chalcone derivative in a nanoemulsion dosage form and identification of the main photodegradation product by LC-MS. | Journal of pharmaceutical and biomedical analysis 20121101 |
| Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations. | Molecules (Basel, Switzerland) 20121101 |
| Letter to the Editor on 'Synthetic cyclohexenyl chalcone natural products possess cytotoxic activities against prostate cancer cells and inhibit cysteine cathepsins in vitro'. | Biochemical and biophysical research communications 20121019 |
| Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. | The Journal of steroid biochemistry and molecular biology 20121001 |
| Synthesis and antimicrobial evaluation of L-phenylalanine-derived C5-substituted rhodanine and chalcone derivatives containing thiobarbituric acid or 2-thioxo-4-thiazolidinone. | European journal of medicinal chemistry 20121001 |
| Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood-brain barrier disruption. | Brain research 20120914 |
| Hydroxysafflor yellow A induces apoptosis in activated hepatic stellate cells through ERK1/2 pathway in vitro. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815 |
| Inhibition of mitogen activated protein kinases increases the sensitivity of A549 lung cancer cells to the cytotoxicity induced by a kava chalcone analog. | Biochemical and biophysical research communications 20120803 |
| The natural compound trans-chalcone induces programmed cell death in Arabidopsis thaliana roots. | Plant, cell & environment 20120801 |
| Antimalarial activity of newly synthesized chalcone derivatives in vitro. | Chemical biology & drug design 20120801 |
| Synthesis and in vitro evaluation of novel tetrazole embedded 1,3,5-trisubstituted pyrazoline derivatives as Entamoeba histolytica growth inhibitors. | European journal of medicinal chemistry 20120801 |
| A SAR study on a series of synthetic lipophilic chalcones as inhibitor of transcription factor NF-κB. | European journal of medicinal chemistry 20120801 |
| Design, synthesis and anticancer activity of nitric oxide donating/chalcone hybrids. | European journal of medicinal chemistry 20120801 |
| Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles. | Bioorganic & medicinal chemistry 20120715 |
| Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. | Bioorganic & medicinal chemistry letters 20120715 |
| Development of a fluorescent chalcone library and its application in the discovery of a mouse embryonic stem cell probe. | Chemical communications (Cambridge, England) 20120707 |
| Flavokawain B, a kava chalcone, induces apoptosis in synovial sarcoma cell lines. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120701 |
| Flavone is efficient to protect zebrafish fins from UV-induced damage. | Drug and chemical toxicology 20120701 |
| The chalcone derivative Chana 1 protects against amyloid β peptide-induced oxidative stress and cognitive impairment. | International journal of molecular medicine 20120701 |
| Synthesis and selective cytotoxic activity of novel hybrid chalcones against prostate cancer cells. | Bioorganic & medicinal chemistry letters 20120701 |
| Synthesis of chalcone derivatives as potential anti-diabetic agents. | Bioorganic & medicinal chemistry letters 20120615 |
| In vitro inhibitory properties of ferrocene-substituted chalcones and aurones on bacterial and human cell cultures. | Dalton transactions (Cambridge, England : 2003) 20120607 |
| In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot). | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120601 |
| Dihydrochalcone glucosides and antioxidant activity from the roots of Anneslea fragrans var. lanceolata. | Phytochemistry 20120601 |
| Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents. | Bioorganic & medicinal chemistry 20120601 |
| Synthesis of a natural chalcone and its prenyl analogs--evaluation of tumor cell growth-inhibitory activities, and effects on cell cycle and apoptosis. | Chemistry & biodiversity 20120601 |
| Synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics. | Molecules (Basel, Switzerland) 20120601 |
| Effects of hydroxy safflower yellow-A on tumor capillary angiogenesis in transplanted human gastric adenocarcinoma BGC-823 tumors in nude mice. | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20120601 |
| Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds. | Dalton transactions (Cambridge, England : 2003) 20120521 |
| Design, synthesis and biological evaluation of novel chalcone derivatives as antitubulin agents. | Bioorganic & medicinal chemistry 20120515 |
| Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice. | Archives of biochemistry and biophysics 20120501 |
| Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores. | Bioorganic & medicinal chemistry 20120501 |
| Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes. | Cell cycle (Georgetown, Tex.) 20120501 |
| [C-ring cleavage of liquiritigenin extracted from licorice roots by an oxygen-tolerant bovine rumen bacterium strain Aeroto-Niu-O16]. | Yao xue xue bao = Acta pharmaceutica Sinica 20120501 |
| Synthesis and biological evaluation of bifendate-chalcone hybrids as a new class of potential P-glycoprotein inhibitors. | Bioorganic & medicinal chemistry 20120415 |
| Chalcone-benzoxaborole hybrid molecules as potent antitrypanosomal agents. | Journal of medicinal chemistry 20120412 |
| Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo. | The Journal of nutritional biochemistry 20120401 |
| Expression of chemokine CXCL12 and its receptor CXCR4 in folliculostellate (FS) cells of the rat anterior pituitary gland: the CXCL12/CXCR4 axis induces interconnection of FS cells. | Endocrinology 20120401 |
| Design, synthesis and biological evaluation of novel (E)-α-benzylsulfonyl chalcone derivatives as potential BRAF inhibitors. | European journal of medicinal chemistry 20120401 |
| Anti-breast cancer activity of heteroaryl chalcone derivatives. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120401 |
| Synthesis and characterization of Ru(II)-DMSO-Cl-chalcone complexes: DNA binding, nuclease, and topoisomerase II inhibitory activity. | Inorganic chemistry 20120305 |
| Inhibitory effects of aurentiacin from Syzygium samarangense on lipopolysaccharide-induced inflammatory response in mouse macrophages. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301 |
| Effects of curcumin and related compounds on processes involving α-hydroxyethyl radicals. | Free radical research 20120301 |
| Methoxychalcone inhibitors of androgen receptor translocation and function. | Bioorganic & medicinal chemistry letters 20120301 |
| Spectral, biological screening of metal chelates of chalcone based Schiff bases of N-(3-aminopropyl) imidazole. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120215 |
| The effects of hydroxysafflor yellow A on blood pressure and cardiac function. | Journal of ethnopharmacology 20120215 |
| Towards dual photodynamic and antiangiogenic agents: design and synthesis of a phthalocyanine-chalcone conjugate. | Organic & biomolecular chemistry 20120214 |
| A synthetic chalcone as a potent inducer of glutathione biosynthesis. | Journal of medicinal chemistry 20120209 |
| Single electron transfer (SET) activity of the dialkyl-amido sodium zincate [(TMEDA)·Na(μ-TMP)(μ-tBu)Zn(tBu)] towards TEMPO and chalcone. | Chemical communications (Cambridge, England) 20120201 |
| Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl(4) -treated mice. | The FEBS journal 20120201 |
| Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. | Journal of ethnopharmacology 20120131 |
| Quantitative structure-activity relationships of mosquito larvicidal chalcone derivatives. | Journal of agricultural and food chemistry 20120118 |
| Synthesis and antimicrobial studies of hydroxylated chalcone derivatives with variable chain length. | Natural product research 20120101 |
| 1,2,3-Triazole tethered β-lactam-chalcone bifunctional hybrids: synthesis and anticancer evaluation. | European journal of medicinal chemistry 20120101 |
| Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents. | European journal of medicinal chemistry 20120101 |
| Synthesis and anticancer activity of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxins as apoptotic inducing agents. | European journal of medicinal chemistry 20120101 |
| Synthesis, anti-inflammatory activity and ulcerogenic liability of novel nitric oxide donating/chalcone hybrids. | Bioorganic & medicinal chemistry 20120101 |
| Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats. | Journal of pharmacological sciences 20120101 |
| Exploring pharmacological significance of chalcone scaffold: a review. | Current medicinal chemistry 20120101 |
| Hydroxysafflor yellow A alleviates early inflammatory response of bleomycin-induced mice lung injury. | Biological & pharmaceutical bulletin 20120101 |
| An efficient synthesis of a potent anti-inflammatory agent, viscolin, and its inducible nitric oxide synthase inhibitory activity. | Chemical & pharmaceutical bulletin 20120101 |
| Relationship between the composition of flavonoids and flower colors variation in tropical water lily (Nymphaea) cultivars. | PloS one 20120101 |
| Chalcone-derived Diels-Alder adducts as NF-κB inhibitors from Morus alba. | Journal of Asian natural products research 20120101 |
| Six new chalcones from Angelica keiskei inducing adiponectin production in 3T3-L1 adipocytes. | Bioscience, biotechnology, and biochemistry 20120101 |
| Hydroxysafflor yellow A attenuates carbon tetrachloride-induced hepatic fibrosis in rats by inhibiting ERK5 signaling. | The American journal of Chinese medicine 20120101 |
| Inhibitory effects of hydroxysafflor yellow A on the formation of advanced glycation end products in vitro. | Biological & pharmaceutical bulletin 20120101 |
| A novel bioactive chalcone of Morus australis inhibits tyrosinase activity and melanin biosynthesis in B16 melanoma cells. | Journal of oleo science 20120101 |
| Synthetic cyclohexenyl chalcone natural products possess cytotoxic activities against prostate cancer cells and inhibit cysteine cathepsins in vitro. | Biochemical and biophysical research communications 20111216 |
| Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors. | Bioorganic & medicinal chemistry letters 20111215 |
| Structure-activity relationships of chalcone analogs as potential inhibitors of ADP- and collagen-induced platelet aggregation. | Bioorganic & medicinal chemistry 20111215 |
| Simultaneous post-transcriptional gene silencing of two different chalcone synthase genes resulting in pure white flowers in the octoploid dahlia. | Planta 20111101 |
| Hydroxysafflor yellow A protects PC12 cells against the apoptosis induced by oxygen and glucose deprivation. | Cellular and molecular neurobiology 20111101 |
| Protective effects of a chalcone derivative against Aβ-induced oxidative stress and neuronal damage. | BMB reports 20111101 |
| Study of DNA interactions with cyclic chalcone derivatives by spectroscopic techniques. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015 |
| Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells. | Bioorganic & medicinal chemistry letters 20111015 |
| Synthesis and anti-bacterial activity of some heterocyclic chalcone derivatives bearing thiofuran, furan, and quinoline moieties. | Archiv der Pharmazie 20111001 |
| Cytotoxicity of chalcone derivatives towards glioblastoma. | Anticancer research 20111001 |
| Anti-tumor activity of new artemisinin-chalcone hybrids. | Archiv der Pharmazie 20111001 |
| Antioxidant and free radical scavenging potential of yakuchinone B derivatives in reduction of lipofuscin formation using H2O2-treated neuroblastoma cells. | Iranian biomedical journal 20111001 |
| 2',5'-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways. | Free radical biology & medicine 20110915 |
| Inhibitory effects of chalcone glycosides isolated from Brassica rapa L. 'hidabeni' and their synthetic derivatives on LPS-induced NO production in microglia. | Bioorganic & medicinal chemistry 20110915 |
| Antifungal action of the oxathiolone-fused chalcone derivative. | Mycoses 20110901 |
| Effect of diethylcarbamazine, butylated hydroxy anisole and methyl substituted chalcone on filarial parasite Setaria cervi: proteomic and biochemical approaches. | Journal of proteomics 20110824 |
| Highly enantioselective synthesis of γ-substituted butenolides via the vinylogous Mukaiyama-Michael reaction catalyzed by a chiral scandium(III)-N,N'-dioxide complex. | Organic & biomolecular chemistry 20110821 |
| Trimethoxy-chalcone derivatives inhibit growth of Leishmania braziliensis: synthesis, biological evaluation, molecular modeling and structure-activity relationship (SAR). | Bioorganic & medicinal chemistry 20110815 |
| Novel oxazine skeletons as potential antiplasmodial active ingredients: Synthesis, in vitro and in vivo biology of some oxazine entities produced via cyclization of novel chalcone intermediates. | Journal of enzyme inhibition and medicinal chemistry 20110801 |
| An experimental study on the effect of safflower yellow on tendon injury-repair in chickens. | The Journal of surgical research 20110801 |
| Synthesis of new chalcone derivatives bearing 2,4-thiazolidinedione and benzoic acid moieties as potential anti-bacterial agents. | European journal of medicinal chemistry 20110801 |
| Synthesis of cyanopyridine and pyrimidine analogues as new anti-inflammatory and antimicrobial agents. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110801 |
| Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids. | Bioorganic & medicinal chemistry letters 20110801 |
| [Studies on pharmacokinetics of hydroxysafflor yellow A in Carthamus tinctorius and its compound preparation in rat]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801 |
| A deuterium-labelling mass spectrometry-tandem diode-array detector screening method for rapid discovery of naturally occurring electrophiles. | Analytical and bioanalytical chemistry 20110701 |
| Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis. | European journal of pharmacology 20110625 |
| Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells. | Journal of medicinal chemistry 20110623 |
| Identification and mapping of a novel hydroxysafflor yellow A (HSYA) biosynthetic gene in Carthamus tinctorius. | Biochemical genetics 20110601 |
| Synthesis and antidyslipidemic activity of chalcone fibrates. | Bioorganic & medicinal chemistry letters 20110601 |
| Effects of novel chalcone derivatives on α-glucosidase, dipeptidyl peptidase-4, and adipocyte differentiation in vitro. | BMB reports 20110601 |
| [Protective effect of hydroxysafflor yellow A on endothelial cell injury induced by lipopolysaccharide]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601 |
| Synthesis and characterization of a symmetric bis(7-hydroxyflavylium) containing a methyl viologen bridge. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110527 |
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. | Journal of medicinal chemistry 20110526 |
| Synthesis, biological evaluation, and molecular docking studies of resveratrol derivatives possessing chalcone moiety as potential antitubulin agents. | Bioorganic & medicinal chemistry 20110415 |
| MD-2 as the target of nonlipid chalcone in the inhibition of endotoxin LPS-induced TLR4 activity. | The Journal of infectious diseases 20110401 |
| [HPLC determination of four components in Tibetan medicine Dangzuo of different Tibetan regions]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401 |
| Ferrocenyl chalcones versus organic chalcones: a comparative study of their nematocidal activity. | Bioorganic & medicinal chemistry 20110315 |
| Photogeneration of reactive oxygen species and photoinduced plasmid DNA cleavage by novel synthetic chalcones. | Journal of photochemistry and photobiology. B, Biology 20110302 |
| Trans-chalcone: a novel small molecule inhibitor of mammalian alpha-amylase. | Molecular biology reports 20110301 |
| Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation. | Molecular nutrition & food research 20110301 |
| Synthesis of chalcone (3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one): advantage of sonochemical method over conventional method. | Ultrasonics sonochemistry 20110301 |
| Cell line studies of glioblastoma and malignant glioma using a newly discovered prenylated chalcone. | Pharmaceutical biology 20110301 |
| Differential inhibition of transmembrane 4 L six family member 5 (TM4SF5)-mediated tumorigenesis by TSAHC and sorafenib. | Cancer biology & therapy 20110201 |
| 3,5,2',4'-Tetrahydroxychalcone, a new non-purine xanthine oxidase inhibitor. | Chemico-biological interactions 20110201 |
| Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe. | Bioorganic & medicinal chemistry letters 20110201 |
| Stercurensin inhibits nuclear factor-κB-dependent inflammatory signals through attenuation of TAK1-TAB1 complex formation. | Journal of cellular biochemistry 20110201 |
| [Inhibitory effect of hydroxysafflor yellow A against PMN activation induced by LPS]. | Yao xue xue bao = Acta pharmaceutica Sinica 20110201 |
| A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of guan-xin-er-hao formula. | Journal of ethnopharmacology 20110127 |
| Synthesis and anti-bacterial activities of a bis-chalcone derived from thiophene and its bis-cyclized products. | Molecules (Basel, Switzerland) 20110112 |
| A trifluoromethyl analog of verbenachalcone promotes neurite outgrowth and cell proliferation of NeuroScreen-1 cells. | Cellular and molecular neurobiology 20110101 |
| Chalcone-based inhibitors against hypoxia-inducible factor 1--structure activity relationship studies. | Bioorganic & medicinal chemistry letters 20110101 |
| Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives. | Bioorganic & medicinal chemistry letters 20110101 |
| Diphenylpropynone derivatives as probes for imaging β-amyloid plaques in Alzheimer's brains. | Bioorganic & medicinal chemistry letters 20110101 |
| Modulation of signaling between TM4SF5 and integrins in tumor microenvironment. | Frontiers in bioscience (Landmark edition) 20110101 |
| 4-Hydroxyderricin from Angelica keiskei roots induces caspase-dependent apoptotic cell death in HL60 human leukemia cells. | Journal of oleo science 20110101 |
| Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS. | Phytochemical analysis : PCA 20110101 |
| A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells. | Molecular cancer 20110101 |
| Enhanced effect and mechanism of water-in-oil microemulsion as an oral delivery system of hydroxysafflor yellow A. | International journal of nanomedicine 20110101 |
| Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice. | The American journal of Chinese medicine 20110101 |
| Design, synthesis and antitumor activity of novel artemisinin derivatives using hybrid approach. | Chemical & pharmaceutical bulletin 20110101 |
| A study of anti-inflammatory and analgesic activity of new 2,4,6-trisubstituted pyrimidines. | Chemical & pharmaceutical bulletin 20110101 |
| Xanthoangelols isolated from Angelica keiskei inhibit inflammatory-induced plasminogen activator inhibitor 1 (PAI-1) production. | BioFactors (Oxford, England) 20110101 |
| Preparation of a series of novel bichalcones linked with a 1,4-dimethylenepiperazine moiety and examination of their cytotoxicity. | Chemical & pharmaceutical bulletin 20110101 |
| Cytoprotective activity of a trans-chalcone against hydrogen peroxide induced toxicity in hepatocellular carcinoma (HepG2) cells. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| The ability of hydroxysafflor yellow a to attenuate lipopolysaccharide-induced pulmonary inflammatory injury in mice. | Phytotherapy research : PTR 20101201 |
| Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity. | European journal of medicinal chemistry 20101201 |
| Synthesis of new chalcone derivatives containing a rhodanine-3-acetic acid moiety with potential anti-bacterial activity. | European journal of medicinal chemistry 20101201 |
| Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents. | Bioorganic & medicinal chemistry 20101201 |
| Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds. | Bioorganic & medicinal chemistry 20101201 |
| Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death. | Bioorganic & medicinal chemistry 20101115 |
| Synthesis of imidazothiazole-chalcone derivatives as anticancer and apoptosis inducing agents. | ChemMedChem 20101108 |
| Anti-tumor effects by a synthetic chalcone compound is mediated by c-Myc-mediated reactive oxygen species production. | Chemico-biological interactions 20101006 |
| Fluorinated 2'-hydroxychalcones as garcinol analogs with enhanced antioxidant and anticancer activities. | Bioorganic & medicinal chemistry letters 20101001 |
| Synthesis and evaluation of novel chalcone derivatives with (99m)Tc/Re complexes as potential probes for detection of β-amyloid plaques. | ACS chemical neuroscience 20100915 |
| Novel 2'-hydroxylfurylchalcones: synthesis and biological activity. | Carbohydrate research 20100903 |
| Highly enantioselective Friedel-Crafts-type alkylation reactions of indoles with chalcone derivatives using a chiral barium catalyst. | Chemistry, an Asian journal 20100903 |
| Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors. | Neurochemical research 20100901 |
| Synthesis and biological evaluation of novel hybrid chalcone derivatives as vasorelaxant agents. | European journal of medicinal chemistry 20100901 |
| Synthesis and anti-cancer activity of chalcone linked imidazolones. | Bioorganic & medicinal chemistry letters 20100815 |
| Radiation and quantum chemical studies of chalcone derivatives. | The journal of physical chemistry. A 20100805 |
| Photodimerizations of hydroxy- and benzoylated 4-azachalcones and quantum chemical investigation of the reactions. | Journal of molecular modeling 20100801 |
| Pharmacophore identification, synthesis, and biological evaluation of carboxylated chalcone derivatives as CysLT1 antagonists. | Bioorganic & medicinal chemistry 20100801 |
| Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei. | Natural product research 20100801 |
| Crotalionosides A-C, three new megastigmane glucosides, two new pterocarpan glucosides and a chalcone C-glucoside from the whole plants of Crotalaria zanzibarica. | Chemical & pharmaceutical bulletin 20100801 |
| [Simultaneous determination of multicomponent in Xuefuzhuyu granule with different UV-wavelength by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801 |
| Antispasmodic and antioxidant activities of fractions and bioactive constituent davidigenin isolated from Mascarenhasia arborescens. | Journal of ethnopharmacology 20100720 |
| Hydroxysafflor Yellow A suppresses thrombin generation and inflammatory responses following focal cerebral ischemia-reperfusion in rats. | Bioorganic & medicinal chemistry letters 20100715 |
| LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. | Plant physiology 20100701 |
| [Protective effect of hydroxysafflor yellow A against acute lung injury induced by oleic acid and lipopolysaccharide in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100701 |
| Synthesis, molecular modeling and biological evaluation of dithiocarbamates as novel antitubulin agents. | Bioorganic & medicinal chemistry 20100615 |
| Synthesis and in vitro study of methylene-bis-tetrahydro[1,3]thiazolo[4,5-c]isoxazoles as potential nematicidal agents. | European journal of medicinal chemistry 20100601 |
| Thiomethoxychalcone-functionalized ferrocene ligands as selective chemodosimeters for mercury(II): single-crystal X-ray structural signature of the [Hg8(mu8-S)(SCH3)12]2+ cluster. | Inorganic chemistry 20100517 |
| Pharmacokinetic comparisons of hydroxysafflower yellow A in normal and blood stasis syndrome rats. | Journal of ethnopharmacology 20100504 |
| The mechanisms for enhanced oral absorption of hydroxysafflor yellow A by chuanxiong volatile oil. | Planta medica 20100501 |
| Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. | European journal of medicinal chemistry 20100501 |
| Prenylated chalcone from Sophora flavescens suppresses Th2 chemokine expression induced by cytokines via heme oxygenase-1 in human keratinocytes. | Archives of pharmacal research 20100501 |
| Cooperative N-heterocyclic carbene/Lewis acid catalysis for highly stereoselective annulation reactions with homoenolates. | Journal of the American Chemical Society 20100421 |
| Isoliquiritigenin 2'-methyl ether induces growth inhibition and apoptosis in oral cancer cells via heme oxygenase-1. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids. | Bioorganic & medicinal chemistry letters 20100401 |
| Total synthesis, antiprotozoal and cytotoxicity activities of rhuschalcone VI and analogs. | Bioorganic & medicinal chemistry 20100401 |
| Sialylation of integrin beta1 is involved in radiation-induced adhesion and migration in human colon cancer cells. | International journal of radiation oncology, biology, physics 20100401 |
| Two new quinochalcones from the florets of Carthamus tinctorius. | Organic letters 20100319 |
| Highly enantioselective Michael addition of cyclopentanone with chalcones via novel di-iminium mechanism. | Chemical communications (Cambridge, England) 20100314 |
| Effects of hydroxysafflor yellow A on the experimental traumatic brain injury in rats. | Journal of Asian natural products research 20100301 |
| Synthesis, characterization, electrochemical studies and antitumor activity of some new chalcone analogues containing ferrocenyl pyrazole moiety. | Bioorganic chemistry 20100201 |
| Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. | European journal of medicinal chemistry 20100201 |
| Synthesis of new chalcone derivatives containing acridinyl moiety with potential antimalarial activity. | European journal of medicinal chemistry 20100201 |
| Screening of biological activities of a series of chalcone derivatives against human pathogenic microorganisms. | Chemistry & biodiversity 20100201 |
| A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent. | Bioorganic & medicinal chemistry 20100115 |
| Effects of hydroxysafflor yellow A in the attenuation of MPTP neurotoxicity in mice. | Neurochemical research 20100101 |
| A continuous spectrophotometric assay for determination of the aureusidin synthase activity of tyrosinase. | Phytochemical analysis : PCA 20100101 |
| Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits. | BMC neuroscience 20100101 |
| Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities. | Journal of medicinal chemistry 20091126 |
| Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity. | Bioorganic & medicinal chemistry 20091115 |
| [Research on technological process of two-pot countercurrent extraction of hydroxysafflor yellow A]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101 |
| A tandem cascade cyclization-electrophilic aromatic substitution: application in the total synthesis of (+)-angelichalcone. | Journal of the American Chemical Society 20091021 |
| Ion-tagged pi-acidic alkene ligands promote Pd-catalysed allyl-aryl couplings in an ionic liquid. | Chemical communications (Cambridge, England) 20091014 |
| Antinociceptive activity of a new benzofuranone derived from a chalcone. | Basic & clinical pharmacology & toxicology 20091001 |
| Study of the anti-inflammatory and analgesic effects of novel rigid benzofuran-3, 4-dihydroxy chalcone by formalin, hot-plate and carrageenan tests in mice. | Pakistan journal of pharmaceutical sciences 20091001 |
| Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisinin against Plasmodium falciparum in vitro. | European journal of medicinal chemistry 20090901 |
| A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta. | Bioorganic & medicinal chemistry letters 20090901 |
| Conjugate addition of indoles to alpha,beta-unsaturated ketones using a Brønsted acid ionic liquid as an efficient catalyst. | Molecules (Basel, Switzerland) 20090827 |
| Effect of the carthamins yellow from Carthamus tinctorius L. on hemorheological disorders of blood stasis in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801 |
| Safflor yellow B suppresses pheochromocytoma cell (PC12) injury induced by oxidative stress via antioxidant system and Bcl-2 /Bax pathway. | Naunyn-Schmiedeberg's archives of pharmacology 20090801 |
| Synthesis of a series of novel dihydroartemisinin derivatives containing a substituted chalcone with greater cytotoxic effects in leukemia cells. | Bioorganic & medicinal chemistry letters 20090801 |
| Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study'. | Phlebology 20090801 |
| Evaluation of anti-inflammatory and analgesic activity of a novel rigid 3, 4-dihydroxy chalcone in mice. | Annals of the New York Academy of Sciences 20090801 |
| Pharmacokinetic properties of hydroxysafflor yellow A in healthy Chinese female volunteers. | Journal of ethnopharmacology 20090730 |
| Visfatin causes endothelium-dependent relaxation in isolated blood vessels. | Biochemical and biophysical research communications 20090612 |
| Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L. | Toxicology in vitro : an international journal published in association with BIBRA 20090601 |
| Two novel monoterpene-chalcone conjugates isolated from the seeds of Alpinia katsumadai. | Bioorganic & medicinal chemistry letters 20090515 |
| Chalcones: a valid scaffold for monoamine oxidases inhibitors. | Journal of medicinal chemistry 20090514 |
| Chalcone derivatives inhibit glutathione S-transferase P1-1 activity: insights into the interaction mode of alpha, beta-unsaturated carbonyl compounds. | Chemical biology & drug design 20090501 |
| Cytoprotective constituents of the heartwood of Caesalpinia sappan on glutamate-induced oxidative damage in HT22 cells. | Biological & pharmaceutical bulletin 20090501 |
| Synthesis of chlorovinyl sulfones as structural analogs of chalcones and their antiplasmodial activities. | European journal of medicinal chemistry 20090401 |
| Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne). | Neurochemical research 20090401 |
| Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative. | Hepatology (Baltimore, Md.) 20090401 |
| Hydroxychalcones induce apoptosis in B16-F10 melanoma cells via GSH and ATP depletion. | European journal of medicinal chemistry 20090401 |
| KB-34, a newly synthesized chalcone derivative, inhibits lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages via heme oxygenase-1 induction and blockade of activator protein-1. | European journal of pharmacology 20090315 |
| Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. | Bioorganic & medicinal chemistry letters 20090315 |
| Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone. | The Journal of antimicrobial chemotherapy 20090301 |
| [Effects of hydroxy safflor yellow A on blood vessel and mRNA expression with VEGF and bFGF of transplantation tumor with gastric adenocarcinoma cell line BGC-823 in nude mice]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301 |
| Copper powder-catalyzed regio- and stereoselective aminobromination of alpha,beta-unsaturated ketones with TsNH2 and NBS as nitrogen and halogen sources. | The Journal of organic chemistry 20090206 |
| Enzymatic formation of unnatural novel chalcone, stilbene, and benzophenone scaffolds by plant type III polyketide synthase. | Organic letters 20090205 |
| Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity. | European journal of medicinal chemistry 20090201 |
| The neuroprotective effects of benzylideneacetophenone derivatives on excitotoxicity and inflammation via phosphorylated Janus tyrosine kinase 2/phosphorylated signal transducer and activator of transcription 3 and mitogen-activated protein K pathways. | The Journal of pharmacology and experimental therapeutics 20090201 |
| Effect of Guanxin No.2 decoction on gene expression in different areas of the myocardial infarcted heart of rats using microarray technology. | The Journal of pharmacy and pharmacology 20090201 |
| Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species. | Journal of natural products 20090101 |
| Effect of Hydroxysafflor yellow A on human umbilical vein endothelial cells under hypoxia. | Vascular pharmacology 20090101 |
| Inhibitory effect of 2,4,2',4'-tetrahydroxy-3-(3-methyl-2-butenyl)-chalcone on tyrosinase activity and melanin biosynthesis. | Biological & pharmaceutical bulletin 20090101 |
| YL-I-108, a synthetic chalcone derivative, inhibits lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 murine macrophages: involvement of heme oxygenase-1 induction and blockade of activator protein-1. | Archives of pharmacal research 20090101 |
| Screening for fractions of Oxytropis falcata Bunge with antibacterial activity. | Natural product research 20090101 |
| A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivo glioblastoma models. | BMC cancer 20090101 |
| 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | Pharmacology 20090101 |
| Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs. | Journal of hematology & oncology 20090101 |
| Nitrochalcones: potential in vivo insulin secretagogues. | Biochimie 20090101 |
| A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of hydroxysafflor yellow A in human plasma: application to a pharmacokinetic study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081201 |
| Material basis for inhibition of Dragon's Blood on evoked discharges of wide dynamic range neurons in spinal dorsal horn of rats. | Science in China. Series C, Life sciences 20081101 |
| Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53. | Cancer prevention research (Philadelphia, Pa.) 20081101 |
| [Quality evaluation of Flos Carthami]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101 |
| Electrospray-assisted laser desorption/ionization mass spectrometry for continuously monitoring the states of ongoing chemical reactions in organic or aqueous solution under ambient conditions. | Analytical chemistry 20081015 |
| Cytotoxic effects of new geranyl chalcone derivatives isolated from the leaves of Artocarpus communis in SW 872 human liposarcoma cells. | Journal of agricultural and food chemistry 20081008 |
| Synthesis and spectral characterization of 2'-hydroxy chalconate complexes of ruthenium(II) and their catalytic and biological applications. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081001 |
| Antifungal activity of chalcones: a mechanistic study using various yeast strains. | European journal of medicinal chemistry 20081001 |
| Spectral properties and inclusion of 3-(4'-dimethylaminophenyl)-1-(2-furanyl)prop-2-en-1-one in organized media of micellar solutions, beta-cyclodextrin and viscous medium. | Colloids and surfaces. B, Biointerfaces 20081001 |
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. | Journal of medicinal chemistry 20080911 |
| Functionalized chalcones with basic functionalities have antibacterial activity against drug sensitive Staphylococcus aureus. | European journal of medicinal chemistry 20080801 |
| Cardioprotective effects of hydroxysafflor yellow A on diabetic cardiac insufficiency attributed to up-regulation of the expression of intracellular calcium handling proteins of sarcoplasmic reticulum in rats. | Phytotherapy research : PTR 20080801 |
| (E)-4-alkoxycarbonylalkylthiochalcones: differentiation of isomeric derivatives by electron ionization mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080801 |
| Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax. | Journal of cardiovascular pharmacology 20080801 |
| Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats. | Archives of pharmacal research 20080801 |
| Efficient synthesis and neuroprotective effect of substituted 1,3-diphenyl-2-propen-1-ones. | Journal of medicinal chemistry 20080710 |
| Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice. | Progress in neuro-psychopharmacology & biological psychiatry 20080701 |
| Enhancing effect of Labrafac Lipophile WL 1349 on oral bioavailability of hydroxysafflor yellow A in rats. | International journal of pharmaceutics 20080624 |
| Binding mode analyses and pharmacophore model development for sulfonamide chalcone derivatives, a new class of alpha-glucosidase inhibitors. | Journal of molecular graphics & modelling 20080601 |
| [Inhibitory action of hydroxysafflor yellow A on inflammatory signal transduction pathway related factors in rats with cerebral cortex ischemia]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080601 |
| Epi-cinchona based thiourea organocatalyst family as an efficient asymmetric Michael addition promoter: enantioselective conjugate addition of nitroalkanes to chalcones and alpha,beta-unsaturated N-acylpyrroles. | The Journal of organic chemistry 20080502 |
| [Hydroxysafflor yellow A up-regulates HIF-1alpha via inhibition of VHL and p53 in Eahy 926 cell line exposed to hypoxia]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080501 |
| Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages. | European journal of pharmacology 20080414 |
| Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity. | Bioorganic & medicinal chemistry letters 20080401 |
| Synthesis and antibacterial activity of littorachalcone and related diphenyl ethers. | Bioorganic & medicinal chemistry letters 20080401 |
| Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma. | Biological & pharmaceutical bulletin 20080401 |
| Characterization of C-glycosyl quinochalcones in Carthamus tinctorius L. by ultraperformance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080401 |
| Inhibitory effect of cochinchinenin B on capsaicin-activated responses in rat dorsal root ganglion neurons. | Brain research 20080327 |
| Trypanocidal activity of a new pterocarpan and other secondary metabolites of plants from Northeastern Brazil flora. | Bioorganic & medicinal chemistry 20080215 |
| Influence of chalcone analogues on serum glucose levels in hyperglycemic rats. | Chemico-biological interactions 20080215 |
| Evidence that hydroxysafflor yellow A protects the heart against ischaemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. | Clinical and experimental pharmacology & physiology 20080201 |
| Spectral properties and inclusion of a hetero-chalcone analogue in organized media of micellar solutions and beta-cyclodextrin. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080201 |
| 2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: design, synthesis, and SAR studies. | Bioorganic & medicinal chemistry letters 20080115 |
| Sulfonate chalcone as new class voltage-dependent K+ channel blocker. | Bioorganic & medicinal chemistry letters 20080101 |
| Protective effects of hydroxysafflor yellow A on acute and chronic congestive cardiac failure mediated by reducing ET-1, NOS and oxidative stress in rats. | The Journal of pharmacy and pharmacology 20080101 |
| Structural characterization and differentiation of isomeric omega-bromoalkoxy derivatives of (E)-chalcone by means of mass spectrometry. | European journal of mass spectrometry (Chichester, England) 20080101 |
| Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action. | Pharmacology 20080101 |
| Aromatherapy research and practice. | Beginnings (American Holistic Nurses' Association) 20080101 |
| Synthesis of chalcone derivatives on steroidal framework and their anticancer activities. | Steroids 20071101 |
| [Selective adsorption of multi-walled carbon nanotubes with liquiritin and isoliquiritin]. | Yao xue xue bao = Acta pharmaceutica Sinica 20071101 |
| Chalcone arrests cell cycle progression and induces apoptosis through induction of mitochondrial pathway and inhibition of nuclear factor kappa B signalling in human bladder cancer cells. | Basic & clinical pharmacology & toxicology 20071001 |
| 2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways. | Biochemical pharmacology 20070915 |
| Orthogonal array design for optimizing extraction efficiency of active constituents from Jakyak-Gamcho Decoction, the complex formula of herbal medicines, Paeoniae Radix and Glycyrrhizae Radix. | Journal of ethnopharmacology 20070905 |
| Simultaneous determination of hydroxysafflor yellow A and ferulic acid in rat plasma after oral administration of the co-extractum of Rhizoma chuanxiong and Flos Carthami by HPLC-diode array detector. | Biomedical chromatography : BMC 20070801 |
| [Study on HPLC fingerprint of water-soluble constituents of Carthamus tinctorius]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070801 |
| Enzymatic effects on reactant and transition states. The case of chalcone isomerase. | Journal of the American Chemical Society 20070725 |
| Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore. | Bioorganic & medicinal chemistry 20070715 |
| Synthesis and fungicidal evaluation of novel chalcone-based strobilurin analogues. | Journal of agricultural and food chemistry 20070711 |
| Combretastatin-chalcone hybrids: synthesis and cytotoxicity. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20070701 |
| Synthesis of 1,3-diphenyl-2-propen-1-one derivatives and evaluation of their biological activities. | Bioorganic & medicinal chemistry 20070615 |
| HPLC determination of safflor yellow A and three active isoflavones from TCM Naodesheng in rat plasma and tissues and its application to pharmacokinetic studies. | Biomedical chromatography : BMC 20070601 |
| Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships. | Bioorganic & medicinal chemistry 20070515 |
| 2-alkenoyl pyridine N-oxides, highly efficient dienophiles for the enantioselective Cu(II)-bis(oxazoline) catalyzed Diels-Alder reaction. | Organic letters 20070510 |
| The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4. | Bioorganic & medicinal chemistry 20070501 |
| Preparation of the traditional Chinese medicine compound recipe Shuxiong sustained-release capsules by multiparticulate time-controlled explosion technology. | Die Pharmazie 20070501 |
| 4'-Acetamidochalcone derivatives as potential antinociceptive agents. | Molecules (Basel, Switzerland) 20070430 |
| Synthesis of alpha,beta-unsaturated ketones as chalcone analogues via a S(RN)1 mechanism. | Molecules (Basel, Switzerland) 20070418 |
| Chemistry and pharmacology of oxyprenylated secondary plant metabolites. | Phytochemistry 20070401 |
| Separation of Liquiritin by simulated moving bed chromatography. | Journal of chromatography. A 20070323 |
| Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile. | Life sciences 20070320 |
| Synthesis, antimycobacterial activity evaluation, and QSAR studies of chalcone derivatives. | Bioorganic & medicinal chemistry letters 20070315 |
| Neuroprotective effects of safflor yellow B on brain ischemic injury. | Experimental brain research 20070301 |
| Determination of hydroxysafflor yellow A in rat plasma and tissues by high-performance liquid chromatography after oral administration of safflower extract or safflor yellow. | Biomedical chromatography : BMC 20070301 |
| Beneficial effect of xanthoangelol, a chalcone compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. | Clinical and experimental pharmacology & physiology 20070301 |
| Identification of yellow dye types in pre-columbian andean textiles. | Analytical chemistry 20070215 |
| Revised structures of gambiriins A1, A2, B1, and B2, chalcane-flavan dimers from gambir (Uncaria gambir extract). | Chemical & pharmaceutical bulletin 20070201 |
| Study on the substituents' effects of a series of synthetic chalcones against the yeast Candida albicans. | European journal of medicinal chemistry 20070101 |
| Cytotoxic Mannich bases of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones. | European journal of medicinal chemistry 20070101 |
| Effects of alpha-substitutions on structure and biological activity of anticancer chalcones. | Bioorganic & medicinal chemistry letters 20061115 |
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
| Effects of the potential chemopreventive agent DMU-135 on adenoma development in the ApcMin+ mouse. | Investigational new drugs 20061101 |
| Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells. | The Journal of nutritional biochemistry 20061001 |
| Microbial metabolism of the prenylated chalcone xanthohumol. | Journal of natural products 20061001 |
| Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin. | Journal of medicinal chemistry 20060921 |
| Synthesis of globo- and isoglobotriosides bearing a cinnamoylphenyl tag as novel electrophilic thiol-specific carbohydrate reagents. | Carbohydrate research 20060904 |
| Isoliquiritigenin selectively inhibits H(2) histamine receptor signaling. | Molecular pharmacology 20060801 |
| [Determination of safflor yellow A by RP-HPLC and resources quality comparison in Carthamus tinctorius]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801 |
| [Preparation of Shuxiong micropellets by centrifugal granulation technology]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060701 |
| Biocatalytic synthesis of butein and sulfuretin by Aspergillus alliaceus. | Journal of agricultural and food chemistry 20060628 |
| Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease. | Bioorganic & medicinal chemistry letters 20060615 |
| Novel bis(1-acyl-2-pyrazolines) of potential anti-inflammatory and molluscicidal properties. | Bioorganic & medicinal chemistry 20060601 |
| Radiolytic transformation of 2,2',4'-trihydroxychalcone. | Radiation research 20060601 |
| Synthesis and evaluation of biological properties of benzylideneacetophenone derivatives. | Archives of pharmacal research 20060601 |
| Modulation of dragon's blood on tetrodotoxin-resistant sodium currents in dorsal root ganglion neurons and identification of its material basis for efficacy. | Science in China. Series C, Life sciences 20060601 |
| Chemical composition of propolis from Canada, its antiradical activity and plant origin. | Natural product research 20060520 |
| Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Anti-angiogenic and anti-tumor activities of 2'-hydroxy-4'-methoxychalcone. | Biological & pharmaceutical bulletin 20060501 |
| Synthesis of verbenachalcone congeners and their biological assessment against activation of the NGF-mediated neurite outgrowth of PC12D cells' activity. | Bioorganic & medicinal chemistry 20060415 |
| Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages. | American journal of physiology. Cell physiology 20060401 |
| New administration model of trans-chalcone biodegradable polymers for the treatment of experimental leishmaniasis. | Acta tropica 20060401 |
| Pharmacokinetics and excretion of hydroxysafflor yellow A, a potent neuroprotective agent from safflower, in rats and dogs. | Planta medica 20060401 |
| Simultaneous determination of components in preparation Naodesheng injection by high performance liquid chromatograph-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI). | Chemical & pharmaceutical bulletin 20060401 |
| Synthesis of chalcone analogues with increased antileishmanial activity. | Bioorganic & medicinal chemistry 20060301 |
| Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats. | Pharmacological research 20060301 |
| Synthesis and PPAR-gamma ligand-binding activity of the new series of 2'-hydroxychalcone and thiazolidinedione derivatives. | Chemical & pharmaceutical bulletin 20060301 |
| Quinone reductase induction as a biomarker for cancer chemoprevention. | Journal of natural products 20060301 |
| Synthesis of Abyssinone II and related compounds as potential chemopreventive agents. | European journal of medicinal chemistry 20060201 |
| Butea monosperma and chemomodulation: protective role against thioacetamide-mediated hepatic alterations in Wistar rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20060201 |
| Cyclooxygenase-2 plays a suppressive role for induction of apoptosis in isoliquiritigenin-treated mouse colon cancer cells. | Cancer letters 20060118 |
| C(alpha)-tetrasubstituted amino acid based peptides in asymmetric catalysis. | Biopolymers 20060101 |
| Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport? | American journal of physiology. Endocrinology and metabolism 20060101 |
| Oligopeptides as catalysts for asymmetric epoxidation. | Biopolymers 20060101 |
| New syntheses and potential antimalarial activities of new 'retinoid-like chalcones'. | European journal of medicinal chemistry 20060101 |
| Asymmetric enone epoxidation by short solid-phase bound peptides: further evidence for catalyst helicity and catalytic activity of individual peptide strands. | Biopolymers 20060101 |
| DPPH radical scavenging reaction of hydroxy- and methoxychalcones. | Bioscience, biotechnology, and biochemistry 20060101 |
| Determination of safflor yellow A, puerarin, ferulic acid, ginsenoside Rg1, and Rb1 in the Traditional Chinese Medicinal preparation Naodesheng injection by high-performance liquid chromatography. | Journal of chromatographic science 20060101 |
| Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads. | Molecular bioSystems 20060101 |
| Microwave-assisted reaction of 2'-hydroxychalcones with hydrazides to synthesize flavanone hydrazone and 4,5-dihydropyrazole derivatives. | Journal of combinatorial chemistry 20060101 |
| Mass spectrometric identification and quantification of glycosyl flavonoids, including dihydrochalcones with neutral loss scan mode. | Analytical biochemistry 20051215 |
| Metabolic engineering of plant cells for biotransformation of hesperedin into neohesperidin, a substrate for production of the low-calorie sweetener and flavor enhancer NHDC. | Journal of agricultural and food chemistry 20051214 |
| Inhibition by licochalcone A, a novel flavonoid isolated from liquorice root, of IL-1beta-induced PGE2 production in human skin fibroblasts. | The Journal of pharmacy and pharmacology 20051201 |
| [Protective effect of hydroxysafflor yellow A on experimental cerebral ischemia in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051201 |
| Combinatorial synthesis and antibacterial evaluation of an indexed chalcone library. | Chemistry & biodiversity 20051201 |
| Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives. | Bioorganic & medicinal chemistry letters 20051115 |
| Flavonoid components and flower color change in transgenic tobacco plants by suppression of chalcone isomerase gene. | FEBS letters 20051107 |
| HPLC analysis of flavokavins and kavapyrones from Piper methysticum Forst. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105 |
| Effect of isoliquiritigenin on viability and differentiated functions of human hepatocytes maintained on PEEK-WC-polyurethane membranes. | Biomaterials 20051101 |
| P-chiral o-phosphinophenol as a P/O hybrid ligand: preparation and use in Cu-catalyzed asymmetric conjugate addition of diethylzinc to acyclic enones. | The Journal of organic chemistry 20051028 |
| Mechanistic insights from reaction progress kinetic analysis of the polypeptide-catalyzed epoxidation of chalcone. | Organic letters 20051027 |
| Monitoring the effects of antagonists on protein-protein interactions with NMR spectroscopy. | Journal of the American Chemical Society 20050928 |
| Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action. | Neuroscience letters 20050923 |
| A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. | Journal of medicinal chemistry 20050922 |
| Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. | Journal of medicinal chemistry 20050908 |
| Content of chalconaringenin and chlorogenic acid in cherry tomatoes is strongly reduced during postharvest ripening. | Journal of agricultural and food chemistry 20050907 |
| [A clinical study of Safflower Yellow injection in treating coronary heart disease angina pectoris with Xin-blood stagnation syndrome]. | Chinese journal of integrative medicine 20050901 |
| Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis. | The Journal of biological chemistry 20050826 |
| Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20050801 |
| Induction of apoptosis in K562 human leukemia cells by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone. | Leukemia research 20050801 |
| Polyphenol profiles of apple juices. | Molecular nutrition & food research 20050801 |
| Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. | Biological & pharmaceutical bulletin 20050801 |
| Therapeutic effects of hydroxysafflor yellow A on focal cerebral ischemic injury in rats and its primary mechanisms. | Journal of Asian natural products research 20050801 |
| In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model. | Cancer chemotherapy and pharmacology 20050701 |
| One step isolation and purification of liquiritigenin and isoliquiritigenin from Glycyrrhiza uralensis Risch. using high-speed counter-current chromatography. | Journal of chromatography. A 20050617 |
| Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents. | Bioorganic & medicinal chemistry letters 20050615 |
| Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells. | Life sciences 20050603 |
| In vitro and in vivo reversal of cancer cell multidrug resistance by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone. | Journal of chemotherapy (Florence, Italy) 20050601 |
| The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. | Life sciences 20050520 |
| In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model. | Cancer chemotherapy and pharmacology 20050501 |
| Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone), a component from Chinese herbal medicine. | Molecular pharmacology 20050501 |
| Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study. | Journal of medicinal chemistry 20050421 |
| Seasonal variations in the level of plant constituents in greenhouse production of cherry tomatoes. | Journal of agricultural and food chemistry 20050420 |
| Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. | Cancer research 20050415 |
| Xanthoangelol D isolated from the roots of Angelica keiskei inhibits endothelin-1 production through the suppression of nuclear factor-kappaB. | Biological & pharmaceutical bulletin 20050401 |
| Synthesis and antimalarial activity of sulfonamide chalcone derivatives. | Farmaco (Societa chimica italiana : 1989) 20050401 |
| Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin. | World journal of gastroenterology 20050321 |
| Degradation of neohesperidin dihydrochalcone by human intestinal bacteria. | Journal of agricultural and food chemistry 20050309 |
| Chalcone-flavone tetramer and biflavones from Aristolochia ridicula. | Phytochemistry 20050301 |
| Galloyl, caffeoyl and hexahydroxydiphenoyl esters of dihydrochalcone glucosides from Balanophora tobiracola. | Phytochemistry 20050301 |
| Dihydrochalcones from the leaves of Pieris japonica. | Journal of natural products 20050301 |
| Highly enantioselective epoxidation of 2,4-diarylenones by using dimeric cinchona phase-transfer catalysts: enhancement of enantioselectivity by surfactants. | Angewandte Chemie (International ed. in English) 20050218 |
| Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression. | Bioorganic & medicinal chemistry letters 20050215 |
| Hydroxychalcones exhibit differential effects on XRE transactivation. | Toxicology 20050214 |
| Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells. | The Journal of pharmacology and experimental therapeutics 20050201 |
| New flavanone and chalcone glucosides from Bidens bipinnata Linn. | Journal of Asian natural products research 20050201 |
| Isoliquiritigenin inhibits cell proliferation and induces apoptosis in human hepatoma cells. | Planta medica 20050201 |
| Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin. | Biological & pharmaceutical bulletin 20050101 |
| Hypotensive and lipid regulatory actions of 4-hydroxyderricin, a chalcone from Angelica keiskei, in stroke-prone spontaneously hypertensive rats. | Clinical and experimental pharmacology & physiology 20050101 |
| Protective effects of chalcone derivatives for acute liver injury in mice. | Archives of pharmacal research 20050101 |
| The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts. | BMC complementary and alternative medicine 20050101 |
| The chemistry and biology of antimitotic chalcones and related enone systems. | Current pharmaceutical design 20050101 |
| [The lipophilic fluorescent probe 4-dimethylaminochalcone: factors responsible for the fluorescence yield]. | Biofizika 20050101 |
| Genista tinctoria hairy root cultures for selective production of isoliquiritigenin. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101 |
| Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. | Biochemical and biophysical research communications 20041210 |
| In vitro anti-tumor activity of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against six established human cancer cell lines. | Pharmacological research 20041101 |
| Synthesis of prenylated benzaldehydes and their use in the synthesis of analogues of licochalcone A. | European journal of medicinal chemistry 20041101 |
| Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. | Phytochemistry 20041101 |
| Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors. | Bioorganic & medicinal chemistry letters 20041018 |
| The subchronic toxicity of hydroxysafflor yellow A of 90 days repeatedly intraperitoneal injections in rats. | Toxicology 20041015 |
| Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells. | Biochemical and biophysical research communications 20041008 |
| Chemical analysis of raw, dry-roasted, and honey-roasted licorice by capillary electrophoresis. | Electrophoresis 20041001 |
| [Protective effect of hydroxysafflor yellow A against rat cortex mitochondrial injuries induced by cerebral ischemia]. | Yao xue xue bao = Acta pharmaceutica Sinica 20041001 |
| The mechanism of polyleucine catalysed asymmetric epoxidation. | Chemical communications (Cambridge, England) 20040921 |
| Chiral amplification by polypeptides and its relevance to prebiotic catalysis. | Chemical communications (Cambridge, England) 20040921 |
| Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. | Biochemical and biophysical research communications 20040910 |
| Isolation and purification of inflacoumarin A and licochalcone A from licorice by high-speed counter-current chromatography. | Journal of chromatography. A 20040903 |
| 3D QSAR studies on antimalarial alkoxylated and hydroxylated chalcones by CoMFA and CoMSIA. | European journal of medicinal chemistry 20040901 |
| Crystal architecture and conformational properties of the inclusion complex, neohesperidin dihydrochalcone-cyclomaltoheptaose (beta-cyclodextrin), by X-ray diffraction. | Carbohydrate research 20040823 |
| A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity. | Bioorganic & medicinal chemistry letters 20040802 |
| Role of nuclear factor-kappaB and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells. | British journal of pharmacology 20040801 |
| Embryotoxicity and teratogenicity study with neohesperidin dihydrochalcone in rats. | Regulatory toxicology and pharmacology : RTP 20040801 |
| Synthesis of deuterium-labeled flavanones. | Chemical & pharmaceutical bulletin 20040801 |
| Anti-allergic activity of naringenin chalcone from a tomato skin extract. | Bioscience, biotechnology, and biochemistry 20040801 |
| Transformation of low-affinity lead compounds into high-affinity protein capture agents. | Chemistry & biology 20040801 |
| Determination of liquiritigenin and isoliquiritigenin in Glycyrrhiza uralensis and its medicinal preparations by capillary electrophoresis with electrochemical detection. | Journal of chromatography. A 20040709 |
| Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells. | Clinical and experimental pharmacology & physiology 20040701 |
| Steric-controlled excimer formation in naphthalene analogues of chalcone. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701 |
| Molecular cytotoxic mechanisms of anticancer hydroxychalcones. | Chemico-biological interactions 20040630 |
| Kinetics of chalcone oxidation by peroxide anion catalysed by poly-l-leucine. | Chemical communications (Cambridge, England) 20040621 |
| Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi. | Journal of agricultural and food chemistry 20040602 |
| First bacterial chalcone isomerase isolated from Eubacterium ramulus. | Archives of microbiology 20040601 |
| Synthesis and cytotoxicity of 2,5-dihydroxychalcones and related compounds. | Archives of pharmacal research 20040601 |
| Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities. | Bioorganic & medicinal chemistry letters 20040517 |
| Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. | Cancer science 20040501 |
| Geranyl chalcone derivatives with antifungal and radical scavenging properties from the leaves of Artocarpus nobilis. | Phytochemistry 20040501 |
| Chalcones as potent tyrosinase inhibitors: the effect of hydroxyl positions and numbers. | Phytochemistry 20040501 |
| [Study on the antioxidative effect of Safflor Yellow]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501 |
| Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3: synthesis and immunosuppressive activity. | Journal of medicinal chemistry 20040422 |
| Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells. | Biochemical pharmacology 20040415 |
| Induction of cell cycle arrest and p21(CIP1/WAF1) expression in human lung cancer cells by isoliquiritigenin. | Cancer letters 20040415 |
| Superacid-catalyzed reactions of cinnamic acids and the role of superelectrophiles. | The Journal of organic chemistry 20040402 |
| Microbial transformations of chalcones: hydroxylation, O-demethylation, and cyclization to flavanones. | Journal of natural products 20040401 |
| Natural antimycobacterial metabolites: current status. | Phytochemistry 20040401 |
| Bacteriostatic action of synthetic polyhydroxylated chalcones against Escherichia coli. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20040401 |
| Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression. | Bioorganic & medicinal chemistry letters 20040322 |
| Thermal and photochemical properties of 4',7-dihydroxyflavylium in water-ionic liquid biphasic systems: a write-read-erase molecular switch. | Angewandte Chemie (International ed. in English) 20040312 |
| Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines. | Bioorganic & medicinal chemistry 20040301 |
| Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats. | Biological & pharmaceutical bulletin 20040301 |
| [Establishment of chromatographic fingerprint and quality assessment of Carthamus tinctorius L. by high performance liquid chromatography]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040301 |
| [Study on distribution of safflor yellow A in tissues of mice]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040301 |
| Synthesis of novel dihydropyridine, dihydropyrimidine, dithioacetal and chalcone derivatives from formylchromones. | Bollettino chimico farmaceutico 20040301 |
| Diprenylated chalcones and other constituents from the twigs of Dorstenia barteri var. subtriangularis. | Phytochemistry 20040201 |
| Cyclobutanes from Combretum albopunctatum. | Phytochemistry 20040201 |
| Determination of butein in rat serum by high performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20040127 |
| Chalcone dimethylallyltransferase from Morus nigra cell cultures. Substrate specificity studies. | FEBS letters 20040116 |
| Dihydrochalcones and coumarins of Esenbeckia grandiflora subsp. brevipetiolata. | Fitoterapia 20040101 |
| Cytotoxic C-benzylated dihydrochalcones from Uvaria acuminata. | Chemical & pharmaceutical bulletin 20040101 |
| Structural assignment of chalcones and differentiation of their isomeric derivatives by electron ionization induced fragmentation. | Rapid communications in mass spectrometry : RCM 20040101 |
| Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101 |
| Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. | Cancer letters 20031125 |
| Some sweet and bitter tastants stimulate inhibitory pathway of adenylyl cyclase via melatonin and alpha 2-adrenergic receptors in Xenopus laevis melanophores. | American journal of physiology. Cell physiology 20031101 |
| Structure determination of minor red pigment in carthamus red colorant isolated by preparative LC/MS. | Food additives and contaminants 20031101 |
| The chalcone butein from Rhus verniciflua shows antifibrogenic activity. | Planta medica 20031101 |
| Polyphenolic profiles in eight apple cultivars using high-performance liquid chromatography (HPLC). | Journal of agricultural and food chemistry 20031008 |
| Substituent effects in the BF3-mediated acylation of phenols with cinnamic acids. | Natural product research 20031001 |
| Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore. | Chemical research in toxicology 20031001 |
| Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | Chemical research in toxicology 20031001 |
| 2'-benzyloxychalcone derivatives stimulate glucose uptake in 3T3-L1 adipocytes. | Life sciences 20030905 |
| Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol. | International journal of cancer 20030901 |
| Therapeutic administration of 3,4,5-trimethoxy-4'-fluorochalcone, a selective inhibitor of iNOS expression, attenuates the development of adjuvant-induced arthritis in rats. | Naunyn-Schmiedeberg's archives of pharmacology 20030901 |
| Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity. | Bioorganic & medicinal chemistry 20030901 |
| The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils. | Naunyn-Schmiedeberg's archives of pharmacology 20030901 |
| Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. | Phytochemistry 20030901 |
| Hypotensive effect of butein via the inhibition of angiotensin converting enzyme. | Biological & pharmaceutical bulletin 20030901 |
| Aldose reductase inhibitors from the nature. | Current medicinal chemistry 20030801 |
| Antioxidant chalcone glycosides and flavanones from Maclura (Chlorophora) tinctoria. | Journal of natural products 20030801 |
| [Studies on chemical constituents of Hedysarum polybotrys]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030801 |
| [Studies on flavonoid constituents of Caragana intermediia]. | Yao xue xue bao = Acta pharmaceutica Sinica 20030801 |
| Structure-activity relationships of antileishmanial and antimalarial chalcones. | Bioorganic & medicinal chemistry 20030703 |
| Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents. | Journal of medicinal chemistry 20030703 |
| Novel antiplasmodial agents. | Medicinal research reviews 20030701 |
| Cytoprotective effects of chalcones from Zuccagnia punctata and melatonin on the gastroduodenal tract in rats. | Pharmacological research 20030701 |
| A new C-benzylated chalcone from Desmos chinensis. | Fitoterapia 20030701 |
| A new chalcone and a flavone from Andrographis neesiana. | Chemical & pharmaceutical bulletin 20030701 |
| Littorachalcone, a new enhancer of NGF-mediated neurite outgrowth, from Verbena littoralis. | Chemical & pharmaceutical bulletin 20030701 |
| [Effects of peroxisome proliferator-activated receptor-gamma agonist on Fas-mediated apoptosis in HT-29 cells]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20030701 |
| Mechanistic approach to the cyclization reaction of a 2'-hydroxychalcone analogue with light and solvent. | Organic & biomolecular chemistry 20030621 |
| 1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601 |
| Natural products as antiparasitic drugs. | Parasitology research 20030601 |
| [Studies on chemical constituents from the root of Polygonatum kingianum]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030601 |
| Dihydrochalcones: evaluation as novel radical scavenging antioxidants. | Journal of agricultural and food chemistry 20030521 |
| Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos. | Bioorganic & medicinal chemistry letters 20030519 |
| Influence of industrial processing on orange juice flavanone solubility and transformation to chalcones under gastrointestinal conditions. | Journal of agricultural and food chemistry 20030507 |
| Isoliquiritigenin inhibits the growth of prostate cancer. | European urology 20030501 |
| Rhuschalcones II-VI, five new bichalcones from the root bark of Rhus pyroides. | Journal of natural products 20030501 |
| Structural characterization and isomer differentiation of chalcones by electrospray ionization tandem mass spectrometry. | Journal of mass spectrometry : JMS 20030501 |
| Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. | Planta medica 20030501 |
| Selective separation of active inhibitors of epidermal growth factor receptor from Caragana jubata by molecularly imprinted solid-phase extraction. | Journal of chromatography. A 20030404 |
| Chalcones from the seed of Cedrelopsis grevei (Ptaeroxylaceae). | Phytochemistry 20030401 |
| Cytotoxic 4'-aminochalcones and related compounds. | Die Pharmazie 20030401 |
| A study on CYP1A inhibitory action of E-2-(4'-methoxybenzylidene)-1-benzosuberone and some related chalcones and cyclic chalcone analogues. | Toxicology 20030303 |
| Legume natural products: understanding and manipulating complex pathways for human and animal health. | Plant physiology 20030301 |
| Transcriptional suppression of the HIV promoter by natural compounds. | Antiviral research 20030301 |
| Butein suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. | The Journal of pharmacy and pharmacology 20030301 |
| Analgesic and antiinflammatory effects of chalcones isolated from Myracrodruon urundeuva allemão. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20030301 |
| Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. | Journal of agricultural and food chemistry 20030226 |
| Enzymes do what is expected (chalcone isomerase versus chorismate mutase). | Journal of the American Chemical Society 20030212 |
| Studies on the chemical constituents of stem bark of Millettia leucantha: isolation of new chalcones with cytotoxic, anti-herpes simplex virus and anti-inflammatory activities. | Chemical & pharmaceutical bulletin 20030201 |
| Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins. | Phytochemistry 20030201 |
| Cytotoxic 2',5'-dihydroxychalcones with unexpected antiangiogenic activity. | European journal of medicinal chemistry 20030201 |
| Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin. | Bioorganic & medicinal chemistry letters 20030106 |
| Structure-activity relationship studies on chalcone derivatives. the potent inhibition of chemical mediators release. | Bioorganic & medicinal chemistry 20030102 |
| Cytotoxic and inhibitory effects of 4,4'-dihydroxy chalcone (RVC-588) on proliferation of human leukemic HL-60 cells. | Leukemia research 20030101 |
| Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionization tandem quadrupole mass spectrometry. | Journal of mass spectrometry : JMS 20030101 |
| [Chalcones (1,3-diarylpropen-1-ones) and their analogs as potential therapeutic agents in cardiovascular system diseases]. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20030101 |
| [Interaction of synthetic analogues of natural chalcones and flavones with guanidine]. | Bioorganicheskaia khimiia 20030101 |
| Simple synthesis of novel diphenylsulfapyrimidine acetates from chalcones and their antimicrobial activity. | Folia microbiologica 20030101 |
| A new sweet dihydrochalcone-glucoside from leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae). | Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101 |
| [Fluorescent probe 4-dimethylaminochalcone: mechanism of fluorescence quenching in nonpolar media]. | Biofizika 20030101 |
| Differential expression of heparin-binding EGF-like growth factor (HB-EGF) mRNA in normal human keratinocytes induced by a variety of natural and synthetic retinoids. | Experimental dermatology 20030101 |
| Development of 3D-QSAR models for 5-lipoxygenase antagonists: chalcones. | Bioorganic & medicinal chemistry 20021201 |
| Isolation and synthesis of chalcones with different degrees of saturation. | Phytochemistry 20021201 |
| Flavonoids from the roots of Millettia erythrocalyx. | Phytochemistry 20021201 |
| Constituents from Miliusa balansae (Annonaceae). | Phytochemistry 20021201 |
| Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. | Journal of natural products 20021201 |
| Fas-mediated signaling enhances sensitivity of human soft tissue sarcoma cells to anticancer drugs by activation of p38 kinase. | Molecular cancer therapeutics 20021201 |
| Electrochemical biosensor for the interaction of DNA with the alkylating agent 4,4'-dihydroxy chalcone based on guanine and adenine signals. | Journal of pharmaceutical and biomedical analysis 20021107 |
| Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. | Journal of natural products 20021101 |
| Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells. | The Journal of steroid biochemistry and molecular biology 20021101 |
| Enzymatic formation of an unnatural C(6)-C(5) aromatic polyketide by plant type III polyketide synthases. | Organic letters 20021017 |
| Efficient liquid-phase synthesis of 2'-hydroxychalcones. | Bioorganic & medicinal chemistry letters 20021007 |
| Increasing antioxidant levels in tomatoes through modification of the flavonoid biosynthetic pathway. | Journal of experimental botany 20021001 |
| Improved synthesis of chalcones under ultrasound irradiation. | Ultrasonics sonochemistry 20021001 |
| Charge transfer fluorescent probes using boronic acids for monosaccharide signaling. | Journal of biomedical optics 20021001 |
| 2',5'-Dihydroxychalcone down-regulates endothelial connexin43 gap junctions and affects MAP kinase activation. | Toxicology 20020930 |
| Quantitative characterization of flavonoid compounds in Rooibos tea (Aspalathus linearis) by LC-UV/DAD. | Journal of agricultural and food chemistry 20020925 |
| Isoliquiritigenin suppresses pulmonary metastasis of mouse renal cell carcinoma. | Cancer letters 20020908 |
| Antimalarial activity of ferrocenyl chalcones. | Bioorganic & medicinal chemistry letters 20020902 |
| Antioxidative components of Psoralea corylifolia (Leguminosae). | Phytotherapy research : PTR 20020901 |
| Methoxychalcones and methoxyflavanones in analytical studies. | Die Pharmazie 20020901 |
| [Antagonistic effect of hydroxysafflor yellow A on the platelet activating factor receptor]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020901 |
| The synthesis and effect of fluorinated chalcone derivatives on nitric oxide production. | Bioorganic & medicinal chemistry letters 20020805 |
| Chalcones and flavonoids as anti-tuberculosis agents. | Bioorganic & medicinal chemistry 20020801 |
| Chalconoid and stilbenoid glycosides from Guibourtia tessmanii. | Phytochemistry 20020801 |
| Synthesis and inhibitory activity of dimethylamino-chalcone derivatives on the induction of nitric oxide synthase. | European journal of medicinal chemistry 20020801 |
| A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis. | Natural product letters 20020801 |
| The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids. | Biochemical and biophysical research communications 20020705 |
| Synthesis, dimerization, and biological activity of hexaoxygenated chalcones related to calythropsin and combretastatins. | Natural product letters 20020601 |
| Excision of transposable elements from the chalcone isomerase and dihydroflavonol 4-reductase genes may contribute to the variegation of the yellow-flowered carnation (Dianthus caryophyllus). | Plant & cell physiology 20020501 |
| In vitro antimycobacterial and antilegionella activity of licochalcone A from Chinese licorice roots. | Planta medica 20020501 |
| Role of hydrogen bonds in the reaction mechanism of chalcone isomerase. | Biochemistry 20020423 |
| Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri. | Phytochemistry 20020401 |
| A new dimeric dihydrochalcone and a new prenylated flavone from the bud covers of Artocarpus altilis: potent inhibitors of cathepsin K. | Journal of natural products 20020401 |
| [A case of drug eruption due to solon]. | Arerugi = [Allergy] 20020401 |
| Synthesis and biological activities of fluorinated chalcone derivatives. | Bioorganic & medicinal chemistry 20020301 |
| Nitric oxide-scavenging properties of some chalcone derivatives. | Nitric oxide : biology and chemistry 20020301 |
| Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines. | International immunopharmacology 20020301 |
| New sensitive and selective fluorescent probes for fluoride using boronic acids. | Analytical biochemistry 20020201 |
| Studies on cancer chemoprevention by traditional folk medicines XXV. Inhibitory effect of isoliquiritigenin on azoxymethane-induced murine colon aberrant crypt focus formation and carcinogenesis. | Biological & pharmaceutical bulletin 20020201 |
| [New therapeutic approaches to peptic ulcer using mucosal protective agents]. | Nihon rinsho. Japanese journal of clinical medicine 20020201 |
| [Sofalcone]. | Nihon rinsho. Japanese journal of clinical medicine 20020201 |
| Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences. | The Journal of biological chemistry 20020111 |
| Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata. | Phytochemistry 20020101 |
| Bifunctional derivative of p,p'-dichlorochalcone. Part III. Synthesis and study for cytotoxic activity of a new compound, 2-[2,2-bis(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-thiazolidin-4-one from p,p'-dichlorochalcone. | European journal of medicinal chemistry 20020101 |
| Electron ionization induced fragmentation of 4-hydroxychalcone derivatives. | Rapid communications in mass spectrometry : RCM 20020101 |
| [The synthesis of chalcone and flavanone semicarbazones from 1,3- and 1,4-dibenzodioxane and 1,5-benzodioxepane analogues of chalcones]. | Bioorganicheskaia khimiia 20020101 |
| Chemical composition of European propolis: expected and unexpected results. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Flavonoids from Tephrosia major. A new prenyl-beta-hydroxychalcone. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Inhibition of epidermal growth factor receptor tyrosine kinase by chalcone derivatives. | Biochimica et biophysica acta 20011217 |
| Antimalarial alkoxylated and hydroxylated chalcones [corrected]: structure-activity relationship analysis. | Journal of medicinal chemistry 20011206 |
| Structure and mechanism of chalcone synthase-like polyketide synthases. | Journal of industrial microbiology & biotechnology 20011201 |
| beta-peptides as catalysts: poly-beta-leucine as a catalyst for the Juliá-Colonna asymmetric epoxidation of enones. | Chemical communications (Cambridge, England) 20011121 |
| Solid state optical activity of dichalcogenides: isolation by chiral crystallization and determination of absolute configuration. | Organic letters 20011115 |
| Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase. | The Journal of biological chemistry 20011102 |
| Asebotin, a dihydrochalcone glucoside from Guibourtia tessmannii. | Fitoterapia 20011101 |
| Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells. | Planta medica 20011101 |
| Some furfural derivatives as nitrification inhibitors. | Journal of agricultural and food chemistry 20011001 |
| Isolation and identification of two new flavanones and a chalcone from Citrus kinokuni. | Chemical & pharmaceutical bulletin 20011001 |
| Chalcone isomerase isozymes with different substrate specificities towards 6'-hydroxy- and 6'-deoxychalcones in cultured cells of Glycyrrhiza echinata, a leguminous plant producing 5-deoxyflavonoids. | Plant & cell physiology 20011001 |
| Aromatase inhibitors from Broussonetia papyrifera. | Journal of natural products 20011001 |
| Leukotoxin-diol: a putative toxic mediator involved in acute respiratory distress syndrome. | American journal of respiratory cell and molecular biology 20011001 |
| [The role of exogenous hRAR beta gene on the growth inhibition and differentiation induction of HL-60R Cells]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20011001 |
| [Pharmacokinetical study of safflor yellow on rat acute model of blood stasis syndrome]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20011001 |
| The effect of the primary structure of the polypeptide catalyst on the enantioselectivity of the Juliá-Colonna asymmetric epoxidation of enones. | Chemical communications (Cambridge, England) 20010907 |
| Inhibition of prostalglandin E2 production by 2'-hydoxychalcone derivatives and the mechanism of action. | The Journal of pharmacy and pharmacology 20010901 |
| Amyloid fibril formation in microwell plates for screening of inhibitors. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20010901 |
| Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding. | Biochemistry 20010828 |
| In vitro antifungal evaluation and structure-activity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall. | Bioorganic & medicinal chemistry 20010801 |
| Anti-HIV and cytotoxic activities of Ru(II)/Ru(III) polypyridyl complexes containing 2,6-(2'-benzimidazolyl)-pyridine/chalcone as co-ligand. | Bioorganic & medicinal chemistry 20010701 |
| Synthesis and biosynthesis of isocordoin. | Planta medica 20010701 |
| Specificity analysis and mechanism of aurone synthesis catalyzed by aureusidin synthase, a polyphenol oxidase homolog responsible for flower coloration. | FEBS letters 20010615 |
| Biflavonoids from Ochna afzelii. | Phytochemistry 20010601 |
| Verbenachalcone, a novel dimeric dihydrochalcone with potentiating activity on nerve growth factor-action from Verbena littoralis. | Journal of natural products 20010601 |
| Anthocyanins and other flavonoids. | Natural product reports 20010601 |
| Synthesis of quinolinyl chalcones and evaluation of their antimalarial activity. | European journal of medicinal chemistry 20010601 |
| Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols. | Nature biotechnology 20010501 |
| Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. | The Journal of pharmacy and pharmacology 20010501 |
| Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells. | Pharmacology & toxicology 20010501 |
| Broussochalcone A, a potent antioxidant and effective suppressor of inducible nitric oxide synthase in lipopolysaccharide-activated macrophages. | Biochemical pharmacology 20010415 |
| Inhibitory effect of DCDC on lipopolysaccharide-induced nitric oxide synthesis in RAW 264.7 cells. | Life sciences 20010413 |
| Artery relaxation by chalcones isolated from the roots of Angelica keiskei. | Planta medica 20010401 |
| Synthesis and antimicrobial properties of N-substituted derivatives of (E)-4-azachalcones. | Farmaco (Societa chimica italiana : 1989) 20010401 |
| [The effects of safflor yellow on microcirculation and hemorheology of acute blood stasis rats]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010401 |
| Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases. | Nature structural biology 20010301 |
| Chemoprotective potentials of homoisoflavonoids and chalcones of Dracaena cinnabari: modulations of drug-metabolizing enzymes and antioxidant activity. | Phytotherapy research : PTR 20010301 |
| In vitro leishmanicidal activity of naturally occurring chalcones. | Phytotherapy research : PTR 20010301 |
| Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1. | Planta medica 20010301 |
| Dihydrochalcones from Piper longicaudatum. | Planta medica 20010301 |
| [Cochinchinenin--a new chalcone dimer from the Chinese dragon blood]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010301 |
| Synthetic and biological activity evaluation studies on novel 1,3-diarylpropenones. | Bioorganic & medicinal chemistry 20010201 |
| Antifungal chalcones from Maclura tinctoria. | Planta medica 20010201 |
| [Determination of neohesperidin dihydrochalcone in foods]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010201 |
| Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53. | Biochemistry 20010116 |
| Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart. | Bioorganic & medicinal chemistry letters 20010108 |
| B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance. | Bioorganic & medicinal chemistry letters 20010108 |
| Chalcones are potent inhibitors of aromatase and 17beta-hydroxysteroid dehydrogenase activities. | Life sciences 20010105 |
| PROP (6-n-Propylthiouracil) tasting and sensory responses to caffeine,sucrose, neohesperidin dihydrochalcone and chocolate. | Chemical senses 20010101 |
| 4-dimethylamino-3',4'-dimethoxychalcone downregulates iNOS expression and exerts anti-inflammatory effects. | Free radical biology & medicine 20010101 |
| Improved water solubility of neohesperidin dihydrochalcone in sweetener blends. | Journal of agricultural and food chemistry 20010101 |
| Synthesis and anti-inflammatory activity of 1-acetyl-5-substituted aryl-3-(beta-aminonaphthyl)-2-pyrazolines and beta-(substituted aminoethyl) amidonaphthalenes. | European journal of medicinal chemistry 20010101 |
| Inhibitory effect of sofalcone on tumor necrosis factor-alpha and interleukin-1 beta production in human monocytes stimulated by Helicobacter pylori water extract. | Drugs under experimental and clinical research 20010101 |
| Serious liver injury. Leading reason for drug removals, restrictions. | FDA consumer 20010101 |
| New bioactive chalcones in propolis from El Salvador. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
| Linked parallel synthesis and MTT bioassay screening of substituted chalcones. | Journal of combinatorial chemistry 20010101 |
| Synthesis and antimicrobial evaluation of chalcone and syndrome derivatives of 4(3H)-quinazolinone. | Bollettino chimico farmaceutico 20010101 |
| Chromene chalcones from Tephrosia carrollii and the revised structure of Oaracacin. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
| Chalcones: structural requirements for antioxidant, estrogenic and antiproliferative activities. | Anticancer research 20010101 |
| Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. | Bioscience, biotechnology, and biochemistry 20000901 |
| Flavonol and chalcone ester glycosides from Bidens leucantha. | Journal of natural products 19970301 |
| Antifungal and antibacterial chalcones from Myrica serrata. | Planta medica 19960201 |
| Inhibition of HIV activation in latently infected cells by flavonoid compounds. | AIDS research and human retroviruses 19960101 |
| Anti-Candida activity of synthetic hydroxychalcones. | Die Pharmazie 19941001 |
| The prevention of adipose differentiation of 3T3-L1 cells caused by retinoic acid is elicited through retinoic acid receptor alpha. | Life sciences 19940101 |
| Commonly occurring plant flavonoids have estrogenic activity. | Molecular pharmacology 19930701 |
| Influence of modulators of epoxide metabolism on the cytotoxicity of trans-anethole in freshly isolated rat hepatocytes. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19920601 |
| Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides. | Antiviral research 19900201 |
| Direct and specific inactivation of rhinovirus by chalcone Ro 09-0410. | Antimicrobial agents and chemotherapy 19821001 |
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