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91-84-9 | Pyrilamine Maleate Salt
CAS No: 91-84-9 Catalog No: AG01FNON MDL No:
Product Description
Catalog Number:
AG01FNON
Chemical Name:
Pyrilamine Maleate Salt
CAS Number:
91-84-9
IUPAC Name:
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
InChI:
InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
InChI Key:
YECBIJXISLIIDS-UHFFFAOYSA-N
EC Number:
202-102-2
UNII:
HPE317O9TL
NSC Number:
13136
Properties
Complexity:
277
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
285.184g/mol
Formal Charge:
0
Heavy Atom Count:
21
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
285.391g/mol
Monoisotopic Mass:
285.184g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
28.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.3
Literature
| Title | Journal |
|---|---|
| Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds. | European journal of medicinal chemistry 20130501 |
| Histamine at low concentrations aggravates rat liver BRL-3A cell injury induced by hypoxia/reoxygenation through histamine H2 receptor in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20130201 |
| Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats. | Pharmaceutical biology 20121101 |
| Ophthalmic antihistamines and H1-H4 receptors. | Current opinion in allergy and clinical immunology 20121001 |
| Dopamine is involved in food-anticipatory activity in mice. | Journal of biological rhythms 20121001 |
| Mast cells and IgE activation do not alter the development of oral tolerance in a murine model. | The Journal of allergy and clinical immunology 20120901 |
| Influence of nitric oxide agents in the dorsal hippocampus of mice on anxiogenic-like effect induced by histamine. | Pharmacology, biochemistry, and behavior 20120901 |
| Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague-Dawley rats. | Pharmaceutical biology 20120901 |
| Edematogenic activity of a sulfated galactan from the red marine algae Gelidium crinale. | Pharmaceutical biology 20120901 |
| Shape-based reprofiling of FDA-approved drugs for the H₁ histamine receptor. | Journal of medicinal chemistry 20120823 |
| Chronic h1-antihistamine treatment increases seizure susceptibility after withdrawal by impairing glutamine synthetase. | CNS neuroscience & therapeutics 20120801 |
| Histaminergic effects on the frequency of repetitive spike firing in rat insular cortex. | Neuroscience letters 20120614 |
| Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan. | Journal of ethnopharmacology 20120614 |
| H1-antihistamines induce vacuolation in astrocytes through macroautophagy. | Toxicology and applied pharmacology 20120415 |
| Mechanisms of intrinsic force in small human airways. | Respiratory physiology & neurobiology 20120415 |
| Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. | Journal of the Chinese Medical Association : JCMA 20120401 |
| pH-dependent complexation of histamine H1 receptor antagonists and human serum albumin studied by UV resonance Raman spectroscopy. | The journal of physical chemistry. B 20120329 |
| A novel fluorescent histamine H(1) receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands. | British journal of pharmacology 20120301 |
| T lymphocytes as a target of histamine action. | Archives of medical science : AMS 20120227 |
| Rational approaches to improving selectivity in drug design. | Journal of medicinal chemistry 20120223 |
| Arousal effects of orexin A on acute alcohol intoxication-induced coma in rats. | Neuropharmacology 20120201 |
| Emodin induces chloride secretion in rat distal colon through activation of mast cells and enteric neurons. | British journal of pharmacology 20120101 |
| Excitatory effect of histamine on rat spinal motoneurons by activation of both H₁ and H₂ receptors in vitro. | Journal of neuroscience research 20120101 |
| Histamine reverses a memory deficit induced in rats by early postnatal maternal deprivation. | Neurobiology of learning and memory 20120101 |
| Strain-dependent effects of the histamine H₄ receptor antagonist JNJ7777120 in a murine model of acute skin inflammation. | Experimental dermatology 20120101 |
| Inverse agonistic activity of antihistamines and suppression of histamine H1 receptor gene expression. | Journal of pharmacological sciences 20120101 |
| Aspirin: pharmacology and clinical applications. | Thrombosis 20120101 |
| Roles of histamine in exercise-induced fatigue: favouring endurance and protecting against exhaustion. | Biological & pharmaceutical bulletin 20120101 |
| Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract. | Lipids in health and disease 20120101 |
| Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation. | PloS one 20120101 |
| Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation. | PloS one 20120101 |
| Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. | PloS one 20120101 |
| Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora. | BMC complementary and alternative medicine 20120101 |
| Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways. | Clinical and translational allergy 20120101 |
| Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy. | PloS one 20120101 |
| Synthesis and evaluation of a series of 2-substituted-5-thiopropylpiperazine (piperidine)-1,3,4-oxadiazoles derivatives as atypical antipsychotics. | PloS one 20120101 |
| Histamine h3 receptor: a novel therapeutic target in alcohol dependence? | Frontiers in systems neuroscience 20120101 |
| Typical and atypical antipsychotic drugs increase extracellular histamine levels in the rat medial prefrontal cortex: contribution of histamine h(1) receptor blockade. | Frontiers in psychiatry 20120101 |
| [Suppression of experimental footpad inflammatory reaction by anti-fungal agent liranaftate in mice]. | Medical mycology journal 20120101 |
| Endothelium-Dependent Vasorelaxant Effect of Butanolic Fraction from Caryocar brasiliense Camb. Leaves in Rat Thoracic Aorta. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Persistent histamine excitation of glutamatergic preoptic neurons. | PloS one 20120101 |
| Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R. | Biochemical pharmacology 20111215 |
| Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor. | Journal of medicinal chemistry 20111208 |
| Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations. | Biochemical pharmacology 20111201 |
| The histaminergic system regulates wakefulness and orexin/hypocretin neuron development via histamine receptor H1 in zebrafish. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111201 |
| Production of the stable human histamine H₁ receptor in Pichia pastoris for structural determination. | Methods (San Diego, Calif.) 20111201 |
| Topical application of betahistine improves eustachian tube function in an animal model. | Acta oto-laryngologica 20111101 |
| Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH(1)R, but low affinity to hH(4)R. | Bioorganic & medicinal chemistry letters 20111101 |
| Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors. | British journal of pharmacology 20111101 |
| Histamine facilitates consolidation of fear extinction. | The international journal of neuropsychopharmacology 20111001 |
| Pyrilamine-induced prolonged QT interval in adolescent with drug overdose. | Pediatric emergency care 20111001 |
| A novel catestatin-induced antiadrenergic mechanism triggered by the endothelial PI3K-eNOS pathway in the myocardium. | Cardiovascular research 20110901 |
| Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia. | The Journal of physiology 20110801 |
| Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
| Synergistic relaxing effect of the paracetamol and pyrilamine combination in isolated human myometrium. | European journal of obstetrics, gynecology, and reproductive biology 20110701 |
| Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells. | Biopharmaceutics & drug disposition 20110701 |
| Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes. | Neuropharmacology 20110601 |
| Regulation of ERK2 phosphorylation by histamine in splenocytes. | Immunopharmacology and immunotoxicology 20110601 |
| Vasorelaxant and hypotensive effects of the extract and the isolated flavonoid rutin obtained from Polygala paniculata L. | The Journal of pharmacy and pharmacology 20110601 |
| Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats. | Biomedical research (Tokyo, Japan) 20110601 |
| Histamine elevates free intracellular calcium in mouse retinal dopaminergic cells via H1-receptors. | Investigative ophthalmology & visual science 20110501 |
| Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms. | Journal of ethnopharmacology 20110412 |
| Prokinetic and laxative activities of Lepidium sativum seed extract with species and tissue selective gut stimulatory actions. | Journal of ethnopharmacology 20110412 |
| Lipopolysaccharide induces H1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells. | Immunology 20110401 |
| Activation of brain histaminergic neurotransmission: a mechanism for cognitive effects of memantine in Alzheimer's disease. | The Journal of pharmacology and experimental therapeutics 20110201 |
| Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids. | Peptides 20110201 |
| [Roles of histamine in the exacerbated allergic dermatitis]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201 |
| Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells. | European journal of pharmacology 20110125 |
| Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats. | European journal of pharmacology 20110110 |
| Analgesic and Anti-Inflammatory Properties of Extracts from the Bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in Mice and Rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Personal reflections on Sir James Black (1924-2010) and histamine. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110101 |
| Artificial neural network combined with principal component analysis for resolution of complex pharmaceutical formulations. | Chemical & pharmaceutical bulletin 20110101 |
| Human epithelial cell cultures from superficial limbal explants. | Molecular vision 20110101 |
| The vasoactive potential of kisspeptin-10 in the peripheral vasculature. | PloS one 20110101 |
| Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis. | Molecular cancer 20110101 |
| Embryo implantation is closely associated with dynamic expression of proprotein convertase 5/6 in the rabbit uterus. | Reproductive biology and endocrinology : RB&E 20110101 |
| The relaxant effect induced by Allium sativum L. bulb aqueous extract on rat isolated trachea. | Pharmacognosy magazine 20110101 |
| Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. | Pharmacological reports : PR 20110101 |
| Real-time visualization of heterotrimeric G protein Gq activation in living cells. | BMC biology 20110101 |
| Proteomic analysis identifies interleukin 11 regulated plasma membrane proteins in human endometrial epithelial cells in vitro. | Reproductive biology and endocrinology : RB&E 20110101 |
| Evaluation of In Vitro Uterotonic Activities of Fruit Extracts of Ficus asperifolia in Rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Capsaicin induces reflex scratching in inflamed skin. | Pharmacology 20110101 |
| Histaminergic mechanisms for modulation of memory systems. | Neural plasticity 20110101 |
| Airway response to acute mechanical stress in a human bronchial model of stretch. | Critical care (London, England) 20110101 |
| Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice. | PloS one 20110101 |
| Inverse agonism and its therapeutic significance. | Indian journal of pharmacology 20110101 |
| Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor. | PloS one 20110101 |
| Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin. | Indian journal of pharmaceutical sciences 20110101 |
| Metabolism of oxycodone in human hepatocytes from different age groups and prediction of hepatic plasma clearance. | Frontiers in pharmacology 20110101 |
| The chemical basis of pharmacology. | Biochemistry 20101207 |
| PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin. | Psychopharmacology 20101201 |
| Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting. | Assay and drug development technologies 20101201 |
| Pharmacological basis for the medicinal use of Holarrhena antidysenterica in gut motility disorders. | Pharmaceutical biology 20101101 |
| Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships. | Bioorganic & medicinal chemistry 20101101 |
| Molecular signaling of pruritus induced by endothelin-1 in mice. | Experimental biology and medicine (Maywood, N.J.) 20101101 |
| Complex actions of neurotensin in ascending and sigmoid colonic muscle: Involvement of enteric mediators. | European journal of pharmacology 20101010 |
| Effects of atypical antipsychotics and haloperidol on PC12 cells: only aripiprazole phosphorylates AMP-activated protein kinase. | Journal of neural transmission (Vienna, Austria : 1996) 20101001 |
| Local histamine H(1-) and H(2)-receptor blockade reduces postexercise skeletal muscle interstitial glucose concentrations in humans. | Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20101001 |
| The effect of intracerebroventricular injection of histamine in visceral nociception induced by acetic acid in rats. | Indian journal of pharmacology 20101001 |
| Uptake of codeine into intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911 |
| Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment. | European journal of obstetrics, gynecology, and reproductive biology 20100901 |
| The essential oil of Croton nepetaefolius selectively blocks histamine-augmented neuronal excitability in guinea-pig celiac ganglion. | The Journal of pharmacy and pharmacology 20100801 |
| Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection. | Journal of psychopharmacology (Oxford, England) 20100601 |
| Ubiquitin/proteasome-dependent down-regulation following clathrin-mediated internalization of histamine H1-receptors in Chinese hamster ovary cells. | Journal of neurochemistry 20100501 |
| Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice. | Archives of Iranian medicine 20100501 |
| Involvement of an influx transporter in the blood-brain barrier transport of naloxone. | Biopharmaceutics & drug disposition 20100501 |
| Effects of histamine H(1) receptor antagonists on delayed spatial win-shift task in rats. | European journal of pharmacology 20100410 |
| Dynamics of PCB removal and detoxification in historically contaminated soils amended with activated carbon. | Environmental pollution (Barking, Essex : 1987) 20100301 |
| Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301 |
| Antihistaminic drugs modify casein-induced inflammation in the rat. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301 |
| Effect of microinjection of histamine into the dorsal hippocampus on the orofacial formalin-induced pain in rats. | European journal of pharmacology 20100210 |
| Blockade of nucleus basalis magnocellularis or activation of insular cortex histamine receptors disrupts formation but not retrieval of aversive taste memory. | Neurobiology of learning and memory 20100201 |
| Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways. | Experimental cell research 20100201 |
| Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice. | Pharmacology, biochemistry, and behavior 20100101 |
| Pretreatment with l-histidine produces a shift from methamphetamine-induced stereotypical biting to persistent locomotion in mice. | Pharmacology, biochemistry, and behavior 20100101 |
| Nitric oxide and histamine signal attempts to swallow: A component of learning that food is inedible in Aplysia. | Learning & memory (Cold Spring Harbor, N.Y.) 20100101 |
| [Histamine H1 receptors modulate the discharge activities of inspiratory neurons in the medial region of neonatal rat nucleus retrofacialis ex vivo]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100101 |
| Leukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigs. | Journal of neuroinflammation 20100101 |
| Genetic variations of the SLC22A5 gene in the Chinese and Indian populations of Singapore. | Drug metabolism and pharmacokinetics 20100101 |
| Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats. | Journal of pharmacological sciences 20100101 |
| Emergence and migration of trunk neural crest cells in a snake, the California Kingsnake (Lampropeltis getula californiae). | BMC developmental biology 20100101 |
| Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts. | Chinese medicine 20100101 |
| Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells in women with endometrial carcinoma. | Reproductive biology and endocrinology : RB&E 20100101 |
| Agarwood induced laxative effects via acetylcholine receptors on loperamide-induced constipation in mice. | Bioscience, biotechnology, and biochemistry 20100101 |
| Efficacy of mepyramine maleate treatment in dogs with angioedema. | Polish journal of veterinary sciences 20100101 |
| Chloroquine-induced Pruritus. | Indian journal of pharmaceutical sciences 20100101 |
| Neural pathways in allergic inflammation. | Journal of allergy 20100101 |
| Nerve growth factor and receptors are significantly affected by histamine stimulus through H1 receptor in pancreatic carcinoma cells. | Molecular medicine reports 20100101 |
| 14C tebuconazole degradation in Colombian soils. | Communications in agricultural and applied biological sciences 20100101 |
| Acute gastroenteritis: from guidelines to real life. | Clinical and experimental gastroenterology 20100101 |
| The effects of histaminergic agents in the nucleus accumbens of rats in the elevated plus-maze test of anxiety. | Iranian journal of psychiatry 20100101 |
| Receptor mediation and nociceptin inhibition of bradykinin-induced plasma extravasation in the knee joint of the rat. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091201 |
| Prevalence and impact of primary dysmenorrhea among Mexican high school students. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20091201 |
| Regulation of human umbilical artery contractility by different serotonin and histamine receptors. | Reproductive sciences (Thousand Oaks, Calif.) 20091201 |
| Genetic deficiency of carnitine/organic cation transporter 2 (slc22a5) is associated with altered tissue distribution of its substrate pyrilamine in mice. | Biopharmaceutics & drug disposition 20091201 |
| The role of mast cells in citric acid-induced airway constriction and cough. | The Chinese journal of physiology 20091130 |
| Olanzapine-induced weight gain in the rat: role of 5-HT2C and histamine H1 receptors. | Psychopharmacology 20091101 |
| Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. | Molecular pharmacology 20091101 |
| Histamine induces human beta-defensin-3 production in human keratinocytes. | Journal of dermatological science 20091101 |
| The ameliorating effects of NMDA receptor agonists on histamine H1 antagonist-induced memory and hippocampal theta disruptions are prevented by the H3 receptor agonist in rats. | Brain research bulletin 20090814 |
| Ameliorative effects of histamine on spatial memory deficits induced by scopolamine infusion into bilateral dorsal or ventral hippocampus as evaluated by the radial arm maze task. | Clinical and experimental pharmacology & physiology 20090801 |
| Chewing rescues stress-suppressed hippocampal long-term potentiation via activation of histamine H1 receptor. | Neuroscience research 20090801 |
| Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. | The Journal of allergy and clinical immunology 20090801 |
| Reverse isotopic response: a rarely reported phenomenon. | International journal of dermatology 20090701 |
| Simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography. | Talanta 20090515 |
| Anomalous photophysics of H1 antihistamines in aqueous solution. | The journal of physical chemistry. B 20090514 |
| Sigma1 receptor antagonists determine the behavioral pattern of the methamphetamine-induced stereotypy in mice. | Psychopharmacology 20090501 |
| Discriminative stimulus properties of the atypical antidepressant, mirtazapine, in rats: a pharmacological characterization. | Psychopharmacology 20090401 |
| Further characterization of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in C57BL/6 mice: role of 5-HT(2A) serotonergic and alpha (1) adrenergic antagonism. | Psychopharmacology 20090401 |
| Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives. | European journal of medicinal chemistry 20090401 |
| Kujin suppresses histamine signaling at the transcriptional level in toluene 2,4-diisocyanate-sensitized rats. | Journal of pharmacological sciences 20090401 |
| Super-additive interaction of the reinforcing effects of cocaine and H1-antihistamines in rhesus monkeys. | Pharmacology, biochemistry, and behavior 20090201 |
| The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate. | Drug metabolism and disposition: the biological fate of chemicals 20090201 |
| Pyrilamine in the horse: detection and pharmacokinetics of pyrilamine and its major urinary metabolite O-desmethylpyrilamine. | Journal of veterinary pharmacology and therapeutics 20090201 |
| Kinetic and pharmacological properties of [(3)H]-histamine transport into cultured type 1 astrocytes from neonatal rats. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090201 |
| Stimulation of histamine H2 receptors activates TRPC3 channels through both phospholipase C and phospholipase D. | European journal of pharmacology 20090114 |
| H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval. | Psychopharmacology 20090101 |
| Effects of hypergravity on histamine H1 receptor mRNA expression in hypothalamus and brainstem of rats: implications for development of motion sickness. | Acta oto-laryngologica 20090101 |
| Effects of inhaled monoethanolamine on bronchoconstriction. | Journal of applied toxicology : JAT 20090101 |
| Characterization of the mechanisms underlying the inflammatory response to Polistes lanio lanio (paper wasp) venom in mouse dorsal skin. | Toxicon : official journal of the International Society on Toxinology 20090101 |
| Inflammatory oedema induced by Lachesis muta muta (Surucucu) venom and LmTX-I in the rat paw and dorsal skin. | Toxicon : official journal of the International Society on Toxinology 20090101 |
| Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model. | International archives of allergy and immunology 20090101 |
| Salivary gland homogenates of Lutzomyia longipalpis and its vasodilatory peptide maxadilan cause plasma leakage via PAC1 receptor activation. | Journal of vascular research 20090101 |
| Impact of sedimentation on wetland carbon sequestration in an agricultural watershed. | Journal of environmental quality 20090101 |
| Cytokine responses of intraepithelial lymphocytes are regulated by histamine H(2) receptor. | Journal of gastroenterology 20090101 |
| Evidence for histamine as a new modulator of carotid body chemoreception. | Advances in experimental medicine and biology 20090101 |
| Design, synthesis and histamine H1-receptor antagonistic activity of some novel 4-amino-2-(substituted)-5-(substituted) aryl-6-[(substituted aryl) amino] pyrimidines. | Arzneimittel-Forschung 20090101 |
| [Analgesic effects of H1 receptor antagonists in the rat model of formalin-induced pain]. | Revista brasileira de anestesiologia 20090101 |
| Expression of nodal signalling components in cycling human endometrium and in endometrial cancer. | Reproductive biology and endocrinology : RB&E 20090101 |
| Genetic variations of the SLC22A4 gene in Chinese and Indian populations of Singapore. | Drug metabolism and pharmacokinetics 20090101 |
| Modulatory effects of histamine on cat carotid body chemoreception. | Respiratory physiology & neurobiology 20081231 |
| Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2? | American journal of physiology. Heart and circulatory physiology 20081201 |
| New 1-benzyl-4-hydroxypiperidine derivatives as non-imidazole histamine H3 receptor antagonists. | Archiv der Pharmazie 20081201 |
| Sorption and desorption of Cd, Cr, Cu, Ni, Pb and Zn by a Fibric Histosol and its organo-mineral fraction. | Journal of hazardous materials 20081130 |
| cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. | Journal of medicinal chemistry 20081127 |
| Effects of mepyramine and famotidine on the physostigmine-induced antinociception in the formalin test in rats. | Pakistan journal of biological sciences : PJBS 20081115 |
| Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone. | Drug metabolism and disposition: the biological fate of chemicals 20081001 |
| Pyrilamine and O-desmethylpyrilamine detection in equine serum and urine. | Journal of analytical toxicology 20081001 |
| Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening. | Journal of medicinal chemistry 20080925 |
| Apomorphine-induced turning behavior in 6-hydroxydopamine lesioned rats is increased by histidine and decreased by histidine decarboxylase, histamine H1 and H2 receptor antagonists, and an H3 receptor agonist. | Pharmacology, biochemistry, and behavior 20080901 |
| Treatment of allergic conjunctivitis with olopatadine hydrochloride eye drops. | Clinical ophthalmology (Auckland, N.Z.) 20080901 |
| Satiety signalling histaminergic system and brain-gut peptides in regulation of food intake in rats with portocaval anastomosis. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801 |
| Exocytosis of a single bovine adrenal chromaffin cell: the electrical and morphological studies. | The journal of physical chemistry. B 20080731 |
| Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. | Journal of medicinal chemistry 20080724 |
| Toward prediction of alkane/water partition coefficients. | Journal of medicinal chemistry 20080710 |
| Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism. | Journal of applied physiology (Bethesda, Md. : 1985) 20080701 |
| Phosphatidylinositol 4,5-bisphosphate hydrolysis mediates histamine-induced KCNQ/M current inhibition. | American journal of physiology. Cell physiology 20080701 |
| [Role of histamine H(1) and H(2) receptors in the modulation of respiratory rhythmical discharge in medulla oblongata slice preparation of neonatal rats]. | Sheng li xue bao : [Acta physiologica Sinica] 20080625 |
| Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: possible origin of pharmacological distortions and side effects. | Toxicology and applied pharmacology 20080615 |
| A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. | Human reproduction (Oxford, England) 20080601 |
| Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection. | Journal of pharmacological sciences 20080601 |
| The activation of histamine-sensitive sites of the ventral hippocampus modulates the consolidation of a learned active avoidance response in rats. | Behavioural brain research 20080516 |
| Antispasmodic activity of essential oil from Lippia dulcis Trev. | Journal of ethnopharmacology 20080417 |
| Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats. | European journal of pharmacology 20080331 |
| The effect of organic amendment on potential mobility and bioavailability of 137Cs and 60Co in tropical soils. | Journal of environmental radioactivity 20080301 |
| Vascular permeability and vasodilation induced by the Loxosceles intermedia venom in rats: involvement of mast cell degranulation, histamine and 5-HT receptors. | Toxicon : official journal of the International Society on Toxinology 20080301 |
| Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats. | Psychopharmacology 20080301 |
| Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta. | Nitric oxide : biology and chemistry 20080301 |
| Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons. | Neuropharmacology 20080301 |
| Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors. | European journal of pharmacology 20080226 |
| In vitro evaluation of gut contractile response to histamine in rainbow trout (Oncorhynchus mykiss Walbaum, 1792). | Research in veterinary science 20080201 |
| The influence of mast cell mediators on migration of SW756 cervical carcinoma cells. | Journal of pharmacological sciences 20080201 |
| Mechanisms underlying the vasorelaxant effect induced by proanthocyanidin-rich fraction from Croton celtidifolius in rat small resistance arteries. | Journal of pharmacological sciences 20080201 |
| Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. | Journal of medicinal chemistry 20080124 |
| Motivated exploratory behaviour in the rat: the role of hippocampus and the histaminergic neurotransmission. | Behavioural brain research 20080110 |
| Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs. | Pulmonary pharmacology & therapeutics 20080101 |
| Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms. | The Journal of pharmacology and experimental therapeutics 20080101 |
| Nerve growth factor enhances neurokinin A-induced airway responses and exhaled nitric oxide via a histamine-dependent mechanism. | Pulmonary pharmacology & therapeutics 20080101 |
| Characterization of the effect of histamine on mouse corpus cavernosum. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101 |
| The synergistic effect of histamine and IL-6 on NGF secretion from cultured astrocytes is evoked by histamine stimulation of IL-6 secretion via H1-receptor-PKC-MAPK signalling pathway. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101 |
| GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. | Pharmacology 20080101 |
| A contraction assay system using established human bronchial smooth muscle cells. | International archives of allergy and immunology 20080101 |
| Studying organic matter molecular assemblage within a whole organic soil by nuclear magnetic resonance. | Journal of environmental quality 20080101 |
| Drug therapy considerations in arrhythmias in children. | Indian pacing and electrophysiology journal 20080101 |
| Pharmacologic effects of grain weevil extract on isolated guinea pig tracheal smooth muscle. | Lung 20080101 |
| Olfactory interference during inhibitory backward pairing in honey bees. | PloS one 20080101 |
| Antinociception induced by central administration of histamine in the formalin test in rats. | Indian journal of physiology and pharmacology 20080101 |
| Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom. | European journal of pharmacology 20071201 |
| Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats. | Neuropharmacology 20071201 |
| Histamine enhances the production of human beta-defensin-2 in human keratinocytes. | American journal of physiology. Cell physiology 20071201 |
| A comparative study of histamine activities on differentiation of osteoblasts and osteoclasts. | The Journal of toxicological sciences 20071201 |
| Proinflammatory and vasodilator effects of nociceptin/orphanin FQ in the rat mesenteric microcirculation are mediated by histamine. | American journal of physiology. Heart and circulatory physiology 20071101 |
| Potentiation of NF-kappaB-dependent transcription and inflammatory mediator release by histamine in human airway epithelial cells. | British journal of pharmacology 20071101 |
| Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa. | Reproduction (Cambridge, England) 20071101 |
| Mast cell-mediated long-lasting increases in excitability of vagal C fibers in guinea pig esophagus. | American journal of physiology. Gastrointestinal and liver physiology 20071001 |
| Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. | PLoS biology 20071001 |
| Functional serotonin and histamine receptor subtypes in porcine ciliary artery in comparison with middle cerebral artery. | European journal of pharmacology 20070910 |
| Histamine receptor H1 and dermatopontin: new downstream targets of the vitamin D receptor. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070901 |
| Histamine ameliorates anti-glomerular basement membrane antibody-induced glomerulonephritis in rats. | Kidney international 20070901 |
| Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors. | The Journal of physiology 20070901 |
| Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice. | Neuropharmacology 20070901 |
| Mechanisms of the vasorelaxant effect of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery. | Life sciences 20070901 |
| Histamine H1-receptors differentially mediate the action of amylin on hypothalamic neurons in control and in overweight rats. | Behavioural brain research 20070822 |
| Indirect mechanism of histamine-induced nociception in temporomandibular joint of rats. | Life sciences 20070809 |
| Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig. | British journal of pharmacology 20070801 |
| Differential effects of histamine on Leydig cell and testicular macrophage activities in wall lizards: precise role of H1/H2 receptor subtypes. | The Journal of endocrinology 20070801 |
| Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations. | Biochemical pharmacology 20070715 |
| Blockade of brain histamine metabolism alters methamphetamine-induced expression pattern of stereotypy in mice via histamine H1 receptors. | Neuroscience 20070713 |
| Role of hippocampal H1 receptors in radial maze performance and hippocampal theta activity in rats. | Brain research bulletin 20070712 |
| In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists. | The Journal of pharmacology and experimental therapeutics 20070701 |
| The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons. | European journal of pharmacology 20070601 |
| Vasodilatory mechanism of levobunolol on vascular smooth muscle cells. | Experimental eye research 20070601 |
| Inhibition of release of vasoactive and inflammatory mediators in airway and vascular tissues and macrophages by a chinese herbal medicine formula for allergic rhinitis. | Evidence-based complementary and alternative medicine : eCAM 20070601 |
| Histamine induces nasal obstruction via calcitonin gene-related peptide in sensitized guinea pigs. | Rhinology 20070601 |
| Cross-talking between calcium and histamine in the expression of MAPKs in hypertensive vascular smooth muscle cells. | Cellular and molecular biology (Noisy-le-Grand, France) 20070515 |
| Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model. | Experimental neurology 20070501 |
| Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice. | Behavioural pharmacology 20070501 |
| Effect of mast cell degranulation on chicken ileal ion transport in vitro. | Poultry science 20070501 |
| Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior. | Biochemical pharmacology 20070415 |
| Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. | Life sciences 20070403 |
| Potentiation by neuropeptide Y of histamine H1 receptor-mediated contraction in rat blood vessels. | Vascular pharmacology 20070401 |
| A comparison between the cardiovascular actions of urocortin 1 and urocortin 2 (stresscopin-related peptide) in conscious rats. | The Journal of pharmacology and experimental therapeutics 20070401 |
| Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine. | Pharmacology, biochemistry, and behavior 20070401 |
| Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription. | Journal of pharmacological sciences 20070401 |
| Neuromuscular blocking agents' differential bronchoconstrictive potential in Guinea pig airways. | Anesthesiology 20070401 |
| Genomic and functional conservation of sedative-hypnotic targets in the zebrafish. | Pharmacogenetics and genomics 20070401 |
| Selective inhibition of Kir currents by antihistamines. | European journal of pharmacology 20070308 |
| Neuroprotective effect of carnosine on necrotic cell death in PC12 cells. | Neuroscience letters 20070306 |
| Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors. | Biochemical pharmacology 20070301 |
| Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: role of H1 receptors in the regulation of IL-4 production. | International immunopharmacology 20070301 |
| Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains. | European journal of pharmacology 20070227 |
| Endothelium-dependent vasodilator effect of Euterpe oleracea Mart. (Açaí) extracts in mesenteric vascular bed of the rat. | Vascular pharmacology 20070201 |
| Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism. | Brain research 20070119 |
| Involvement of substance P and neurogenic inflammation in arsenic-induced early vascular dysfunction. | Toxicological sciences : an official journal of the Society of Toxicology 20070101 |
| Changes in self-reactive IgG antibody repertoire after treatment of experimental autoimmune encephalomyelitis with anti-allergic drugs. | Journal of neuroimmunology 20070101 |
| Effects of impromidine- and arpromidine-derived guanidines on recombinant human and guinea pig histamine H1 and H2 receptors. | Archiv der Pharmazie 20070101 |
| Laser capture microdissection and cDNA array analysis of endometrium identify CCL16 and CCL21 as epithelial-derived inflammatory mediators associated with endometriosis. | Reproductive biology and endocrinology : RB&E 20070101 |
| Histamine-induced contraction and relaxation of placental chorionic plate arteries. | Placenta 20070101 |
| Role of apolipoprotein E in anxiety. | Neural plasticity 20070101 |
| Patterns of prescription and self-medication for treating primary dysmenorrhea in a Mexican population. | Proceedings of the Western Pharmacology Society 20070101 |
| Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. | The Journal of experimental medicine 20061225 |
| Striking differences of action of lisuride stereoisomers at histamine H1 receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20061201 |
| Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway. | The European journal of neuroscience 20061201 |
| Mechanism of imipramine-induced seizures in amygdala-kindled rats. | Epilepsy research 20061101 |
| Histamine differentially interacts with tumor necrosis factor-alpha and thrombin in endothelial tissue factor induction: the role of c-Jun NH2-terminal kinase. | Journal of thrombosis and haemostasis : JTH 20061101 |
| Localized expression of histamine H1 receptors in syncytiotrophoblast cells of human placenta. | Journal of pharmacological sciences 20061101 |
| The effects of histaminergic agents in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety. | Pharmacology, biochemistry, and behavior 20061101 |
| Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes. | Bioorganic & medicinal chemistry 20061001 |
| Mutation in an adaptor protein PDZK1 affects transport activity of organic cation transporter OCTNs and oligopeptide transporter PEPT2. | Drug metabolism and pharmacokinetics 20061001 |
| Involvement of central H1 and H2 receptors in water intake induced by hyperosmolarity, hypovolemia and central cholinergic stimulation. | Physiology & behavior 20060930 |
| Histamine-induced ion secretion across rat distal colon: involvement of histamine H1 and H2 receptors. | European journal of pharmacology 20060928 |
| Histaminergic receptors of medial septum and conditioned place preference: D1 dopamine receptor mechanism. | Brain research 20060913 |
| Neuroprotective effects of hibernation-regulating substances against low-temperature-induced cell death in cultured hamster hippocampal neurons. | Brain research 20060907 |
| Histamine induces interleukin-6 expression in the human synovial sarcoma cell line (SW982) through the H1 receptor. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060901 |
| Suppression of ischemia/reperfusion liver injury by histamine H4 receptor stimulation in rats. | European journal of pharmacology 20060821 |
| The vasorelaxant effect of adrenomedullin, proadrenomedullin N-terminal 20 peptide and amylin in human skin. | Basic & clinical pharmacology & toxicology 20060801 |
| Histamine enhances inhibitory avoidance memory consolidation through a H2 receptor-dependent mechanism. | Neurobiology of learning and memory 20060701 |
| Angiotensin II potentiates inflammatory edema in rats: Role of mast cell degranulation. | European journal of pharmacology 20060701 |
| Time-frequency analysis of spike-wave discharges using a modified wavelet transform. | Journal of neuroscience methods 20060630 |
| N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors. | The Journal of pharmacology and experimental therapeutics 20060601 |
| Histamine modulates mast cell degranulation through an indirect mechanism in a model IgE-mediated reaction. | European journal of immunology 20060601 |
| The effect of histamine on field-stimulated contractions of the guinea-pig prostate. | Naunyn-Schmiedeberg's archives of pharmacology 20060601 |
| The effects of histaminergic agents in the ventral hippocampus of rats in the plus-maze test of anxiety-like behaviours. | Physiology & behavior 20060530 |
| Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures. | Regulatory peptides 20060515 |
| Effect of endogenous histamine in the ventral hippocampus on fear memory deficits induced by scopolamine as evaluated by step-through avoidance response in rats. | Physiology & behavior 20060415 |
| Mechanisms of the vasorelaxant effect of Danshen (Salvia miltiorrhiza) in rat knee joints. | Journal of ethnopharmacology 20060406 |
| Orally administered FPRL1 receptor agonist peptide MMK-1 inhibits etoposide-induced alopecia by a mechanism different from intraperitoneally administered MMK-1. | Peptides 20060401 |
| Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. | British journal of pharmacology 20060401 |
| The role of histamine in the intracellular survival of Mycobacterium bovis BCG. | Microbes and infection 20060401 |
| Extract of the bristles of Dirphia sp. increases nitric oxide in a rat pleurisy model. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401 |
| Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury. | Experimental neurology 20060301 |
| Role of H1 receptors in histamine-mediated up-regulation of STAT4 phosphorylation. | International immunopharmacology 20060301 |
| Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways. | Journal of neurochemistry 20060301 |
| Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle. | Behavioural pharmacology 20060301 |
| Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. | Journal of natural products 20060301 |
| Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications. | Neuropsychiatric disease and treatment 20060301 |
| Transcription of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase type 3 gene, ATP2A3, is regulated by the calcineurin/NFAT pathway in endothelial cells. | The Biochemical journal 20060215 |
| Minimal role for H1 and H2 histamine receptors in cutaneous thermal hyperemia to local heating in humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20060201 |
| Differential modulation of cell recruitment and acute edema in a model of Polybia paulista venom-induced inflammation. | International immunopharmacology 20060201 |
| Histamine increases sickle erythrocyte adherence to endothelium. | British journal of haematology 20060201 |
| Evaluation of the protective effects of histamine and 5-hydroxytryptamine receptor antagonists against the lethal toxicity induced by oxygen free radicals in rats. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20060201 |
| Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125 |
| Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2. | European journal of pharmacology 20060120 |
| Changes in pH differently affect the binding properties of histamine H1 receptor antagonists. | European journal of pharmacology 20060120 |
| Involvement of skin barrier dysfunction in itch-related scratching in special diet-fed hairless mice. | European journal of pharmacology 20060113 |
| Cetirizine-induced dystonic movements. | Neurology 20060110 |
| Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice. | Behavioural brain research 20060106 |
| Enhanced histamine-mediated contraction of rabbit penile dorsal artery in diet-induced hypercholesterolemia. | Vascular pharmacology 20060101 |
| Putting theory into practice: James Black, receptor theory and the development of the beta-blockers at ICI, 1958-1978. | Medical history 20060101 |
| Mast cell degranulation alters lymphatic contractile activity through action of histamine. | Microcirculation (New York, N.Y. : 1994) 20060101 |
| Histamine receptors influence blood-spinal cord barrier permeability, edema formation, and spinal cord blood flow following trauma to the rat spinal cord. | Acta neurochirurgica. Supplement 20060101 |
| Increased expression of inducible nitric oxide synthase in nasal mucosae of guinea pigs with induced allergic rhinitis. | American journal of rhinology 20060101 |
| Mechanisms of histamine-induced relaxation in bovine small adrenal cortical arteries. | American journal of physiology. Endocrinology and metabolism 20051201 |
| The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety. | Behavioural pharmacology 20051201 |
| Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats. | Acta pharmacologica Sinica 20051201 |
| Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells. | Reproduction (Cambridge, England) 20051201 |
| 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. | Journal of medicinal chemistry 20051103 |
| Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs. | The Journal of pharmacology and experimental therapeutics 20051101 |
| Neurokinin-1 receptor desensitization to consecutive microdialysis infusions of substance P in human skin. | The Journal of physiology 20051101 |
| Intracerebroventricular effects of histaminergic agents on morphine-induced anxiolysis in the elevated plus-maze in rats. | Basic & clinical pharmacology & toxicology 20051101 |
| Species differences in the gut stimulatory effects of radish seeds. | The Journal of pharmacy and pharmacology 20051101 |
| Some environmental contaminants influence motor and feeding behaviors in the ornate wrasse (Thalassoma pavo) via distinct cerebral histamine receptor subtypes. | Environmental health perspectives 20051101 |
| Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice. | European journal of pharmacology 20051017 |
| Mechanism of the endothelium-dependent vasodilator effect of an alcohol-free extract obtained from a vinifera grape skin. | Pharmacological research 20051001 |
| Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis. | Pharmacology 20051001 |
| Histamine receptors and the conjunctiva. | Current opinion in allergy and clinical immunology 20051001 |
| Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. | Vascular pharmacology 20051001 |
| Histamine H1 antagonists block M-currents in dissociated rat cortical neurons. | Brain research 20050928 |
| Cross state-dependent retrieval between histamine and lithium. | Physiology & behavior 20050915 |
| Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats. | Peptides 20050901 |
| Antihypertensive and endothelium-dependent vasodilator effects of Alpinia zerumbet, a medicinal plant. | Journal of cardiovascular pharmacology 20050901 |
| Gastrointestinal stimulatory and uterotonic activities of dietary radish leaves extract are mediated through multiple pathways. | Phytotherapy research : PTR 20050901 |
| Mast cell mediators in citric acid-induced airway constriction of guinea pigs. | Toxicology and applied pharmacology 20050815 |
| Anti-alopecia effect of Gly-Leu-Phe, an immunostimulating peptide derived from alpha-lactalbumin. | Bioscience, biotechnology, and biochemistry 20050801 |
| Involvement of the βγ subunits of G proteins in the cAMP response induced by stimulation of the histamine H1 receptor. | Naunyn-Schmiedeberg's archives of pharmacology 20050801 |
| [3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction. | European journal of pharmacology 20050725 |
| Histamine induces tissue factor expression: implications for acute coronary syndromes. | Circulation 20050719 |
| Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists. | International immunopharmacology 20050701 |
| Histamine excites noradrenergic neurons in locus coeruleus in rats. | Neuropharmacology 20050701 |
| Linking agonist binding to histamine H1 receptor activation. | Nature chemical biology 20050701 |
| Delineation of receptor-ligand interactions at the human histamine H1 receptor by a combined approach of site-directed mutagenesis and computational techniques - or - how to bind the H1 receptor. | Archiv der Pharmazie 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). | Journal of medicinal chemistry 20050505 |
| Anti-alopecia mechanisms of soymetide-4, an immunostimulating peptide derived from soy beta-conglycinin. | Peptides 20050501 |
| Influence of intracerebroventricular administration of histaminergic drugs on morphine state-dependent memory in the step-down passive avoidance test. | Pharmacology 20050501 |
| Pharmacological differences between human and guinea pig histamine H1 receptors: Asn84 (2.61) as key residue within an additional binding pocket in the H1 receptor. | Molecular pharmacology 20050401 |
| Dual effect of pyrilamine on absence seizures in WAG/Rij rats. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050401 |
| The role of endogenous histamine on the pathogenesis of the lipopolysaccharide (LPS)-induced, acute lung injury: a pilot study. | Inflammation 20050401 |
| Prevention of brain infarction by postischemic administration of histidine in rats. | Brain research 20050328 |
| Histamine induces opposing vasoactive effects at different levels of the ocular vasculature. | Current eye research 20050301 |
| Relaxant effects of the neutral extract of the leaves of Bidens pilosa Linn on isolated rat vascular smooth muscle. | Phytotherapy research : PTR 20050301 |
| Central H1 and H2 receptor participation in the control of water and salt intake in rats. | Physiology & behavior 20050215 |
| Discriminative stimulus properties of the atypical antipsychotic clozapine and the typical antipsychotic chlorpromazine in a three-choice drug discrimination procedure in rats. | Psychopharmacology 20050201 |
| Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats. | European journal of pharmacology 20050131 |
| Comparative anticholinergic activities of 10 histamine H1 receptor antagonists in two functional models. | European journal of pharmacology 20050104 |
| Mast cells in citric acid-induced cough of guinea pigs. | Toxicology and applied pharmacology 20050101 |
| Pharmacological study of oyster mushroom (Pleurotus ostreatus) extract on isolated guinea pig trachea smooth muscle. | Lung 20050101 |
| Histamine-induced cyclic AMP formation in the chick hypothalamus: interaction with vasoactive intestinal peptide. | Pharmacological reports : PR 20050101 |
| Non-imidazole histamine NO-donor H3-antagonists. | Farmaco (Societa chimica italiana : 1989) 20050101 |
| Pharmacological basis for the gut stimulatory activity of Raphanus sativus leaves. | Journal of ethnopharmacology 20041201 |
| Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor. | International archives of allergy and immunology 20041201 |
| The anorectic effect of neurotensin is mediated via a histamine H1 receptor in mice. | Peptides 20041201 |
| Homologous and heterologous phosphorylations of human histamine H1 receptor in intact cells. | Journal of pharmacological sciences 20041201 |
| Unusual functional properties of homo- and heteromultimeric histamine-gated chloride channels of Drosophila melanogaster: spontaneous currents and dual gating by GABA and histamine. | Neuroscience letters 20041130 |
| H1 but not H2 histamine receptor activation contributes to the rise in skin blood flow during whole body heating in humans. | The Journal of physiology 20041101 |
| Homology modelling and binding site mapping of the human histamine H1 receptor. | European journal of medicinal chemistry 20041101 |
| Effect of glucocorticoid on upregulation of histamine H1 receptor mRNA in nasal mucosa of rats sensitized by exposure to toluene diisocyanate. | Acta oto-laryngologica 20041101 |
| Sex differences in mouse behavior following pyrilamine treatment: role of histamine 1 receptors in arousal. | Pharmacology, biochemistry, and behavior 20041101 |
| Role of the histamine system in nefopam-induced antinociception in mice. | European journal of pharmacology 20041025 |
| Participation of histaminergic H1 and noradrenergic alpha 1 receptors in orexin A-induced wakefulness in rats. | Brain research 20041008 |
| Domain swapping in the human histamine H1 receptor. | The Journal of pharmacology and experimental therapeutics 20041001 |
| Ligand-directed functional heterogeneity of histamine H1 receptors: novel dual-function ligands selectively activate and block H1-mediated phospholipase C and adenylyl cyclase signaling. | The Journal of pharmacology and experimental therapeutics 20041001 |
| Degranulation of mast cells located in median eminence in response to compound 48/80 evokes adrenocortical secretion via histamine and CRF in dogs. | American journal of physiology. Regulatory, integrative and comparative physiology 20041001 |
| The in vitro and in vivo pharmacological activity of Boiga dendrophila (mangrove catsnake) venom. | Autonomic & autacoid pharmacology 20041001 |
| Blockade of calcium entry in smooth muscle cells by the antidepressant imipramine. | Biochemical pharmacology 20040901 |
| Histaminergic H1 and H2 receptors located within the ventromedial hypothalamus regulate food and water intake in rats. | Pharmacology, biochemistry, and behavior 20040901 |
| Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine. | Journal of cardiovascular pharmacology 20040901 |
| Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein. | The Journal of biological chemistry 20040813 |
| L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2. | American journal of physiology. Cell physiology 20040801 |
| Histamine H1 receptor down-regulation mediated by M3 muscarinic acetylcholine receptor subtype. | Journal of pharmacological sciences 20040801 |
| Glutamic acid and histamine-sensitive neurons in the ventral hippocampus and the basolateral amygdala of the rat: functional interaction on memory and learning processes. | Behavioural brain research 20040709 |
| Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor. | European journal of biochemistry 20040701 |
| Pharmacological and histopathological characterization of Bothrops lanceolatus (Fer de lance) venom-induced edema. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040701 |
| Effects of second-generation histamine H1 receptor antagonists on the sleep-wakefulness cycle in rats. | European journal of pharmacology 20040628 |
| Regulation of cytokine production in carcinoembryonic antigen stimulated Kupffer cells by beta-2 adrenergic receptors: implications for hepatic metastasis. | Cancer letters 20040625 |
| [Camouflaged H1-antihistaminic and road-traffic accident]. | Medicina clinica 20040612 |
| ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel histamine H1 receptor antagonist, produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and neuropathy. | The Journal of pharmacology and experimental therapeutics 20040601 |
| Activation of histamine H1-receptor enhances neurotrophic factor secretion from cultured astrocytes. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040601 |
| Cardiovascular effects of the toxin(s) of the Australian paralysis tick, Ixodes holocyclus, in the rat. | Toxicon : official journal of the International Society on Toxinology 20040601 |
| Effect of the histamine H3-antagonist clobenpropit on spatial memory deficits induced by MK-801 as evaluated by radial maze in Sprague-Dawley rats. | Behavioural brain research 20040505 |
| Involvement of histaminergic system in the discriminative stimulus effects of morphine. | European journal of pharmacology 20040503 |
| Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice. | British journal of pharmacology 20040501 |
| Influx and efflux transport of H1-antagonist epinastine across the blood-brain barrier. | Drug metabolism and disposition: the biological fate of chemicals 20040501 |
| [Reversing effect of histamine on neuron death induced by N-methyl-D-aspartate]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040501 |
| Pharmacological studies on the venomous spotted butterfish (Scatophagus argus Linn) sting extract on experimental animals. | Indian journal of experimental biology 20040501 |
| Histamine enhances the production of granulocyte-macrophage colony-stimulating factor via protein kinase Calpha and extracellular signal-regulated kinase in human keratinocytes. | The Journal of investigative dermatology 20040401 |
| Identification of amino acid residues responsible for agonist-induced down-regulation of histamine H(1) receptors. | Journal of pharmacological sciences 20040401 |
| Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy. | Journal of pharmacological sciences 20040401 |
| Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens. | European journal of pharmacology 20040308 |
| Role of H3-receptor-mediated signaling in anxiety and cognition in wild-type and Apoe-/- mice. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301 |
| Novel dual acting molecules possessing 5-lipoxygenase enzyme inhibition and histamine H(1) receptor antagonist properties. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301 |
| Expression of histamine H(1) receptor in placenta. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301 |
| Alleviation of ischemic neuronal damage by postischemic loading with histidine in the rat striatum. | Brain research 20040213 |
| Anxiolytic-like effects of escitalopram, citalopram, and R-citalopram in maternally separated mouse pups. | The Journal of pharmacology and experimental therapeutics 20040201 |
| Inhibition of nitric oxide synthesis potentiates the colonic permeability increase triggered by luminal bile acids. | Acta physiologica Scandinavica 20040201 |
| Alleviation of ischemic neuronal damage by histamine H2 receptor stimulation in the rat striatum. | European journal of pharmacology 20040126 |
| Characterization of the effects of receptor-selective ligands in rats discriminating the novel antipsychotic quetiapine. | Psychopharmacology 20040101 |
| Histaminergic effect of crude papaya latex on isolated guinea pig ileal strips. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101 |
| Pharmacological studies of the effect of wheat grain extract. | Respiration; international review of thoracic diseases 20040101 |
| Pertussis toxin-sensitive G protein modulates the ability of histamine to stimulate cAMP production in the chick pineal gland. | Polish journal of pharmacology 20040101 |
| Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists. | Journal of medicinal chemistry 20031218 |
| Effects of clobenpropit on pentylenetetrazole-kindled seizures in rats. | European journal of pharmacology 20031215 |
| N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists. | Journal of medicinal chemistry 20031204 |
| Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo. | The Journal of pharmacology and experimental therapeutics 20031201 |
| Hypotensive activity of the ethanol extract of Pavetta crassipes leaves. | Biological & pharmaceutical bulletin 20031201 |
| Multiple cedar pollen challenge diminishes involvement of histamine in allergic conjunctivitis of Guinea pigs. | Biological & pharmaceutical bulletin 20031201 |
| Interactions of olopatadine and selected antihistamines with model and natural membranes. | Ocular immunology and inflammation 20031201 |
| Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig. | Journal of pharmacological sciences 20031201 |
| Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats. | Brain research 20031121 |
| Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. | British journal of pharmacology 20031101 |
| Interactions of eosinophil granule proteins with skin: limits of detection, persistence, and vasopermeabilization. | The Journal of allergy and clinical immunology 20031101 |
| Direct phosphorylation of histamine H1 receptor by various protein kinases in vitro. | Methods and findings in experimental and clinical pharmacology 20031101 |
| Signaling via histamine receptors in cat duodenal smooth muscle cells. | Molecules and cells 20031031 |
| Effect of morphine, naloxone and histamine system on water intake in adult male rats. | European journal of pharmacology 20031008 |
| Pro-apoptotic effect of high concentrations of histamine on human neutrophils. | International immunopharmacology 20031001 |
| Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | The Journal of pharmacology and experimental therapeutics 20031001 |
| Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion. | Journal of neuroendocrinology 20031001 |
| Histamine stimulates the proliferation of human articular chondrocytes in vitro and is expressed by chondrocytes in osteoarthritic cartilage. | Annals of the rheumatic diseases 20031001 |
| Submucosal microinfusion of endothelin and adrenaline mobilizes ECL-cell histamine in rat stomach, and causes mucosal damage: a microdialysis study. | British journal of pharmacology 20031001 |
| Influence of histamine in a liver injury model induced by Propionibacterium acnes and lipopolysaccharide. | Biological & pharmaceutical bulletin 20031001 |
| Pharmacological characterization of mouse hind paw oedema induced by Bothrops insularis (jararaca ilhoa) snake venom. | Toxicon : official journal of the International Society on Toxinology 20031001 |
| Aminergic control of high-frequency (approximately 200 Hz) network oscillations in the hippocampus of the behaving rat. | Neuroscience letters 20030911 |
| Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7. | American journal of physiology. Cell physiology 20030901 |
| Possible involvement of opioid receptors in moclobemide-induced hypothermia in mice. | Pharmacological research 20030901 |
| Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats. | Pharmacology 20030901 |
| Mechanism of anti-nociceptive effects of Asarum sieboldii Miq. radix: potential role of bradykinin, histamine and opioid receptor-mediated pathways. | Journal of ethnopharmacology 20030901 |
| Histamine enhances the production of nerve growth factor in human keratinocytes. | The Journal of investigative dermatology 20030901 |
| IL-4 primes human endothelial cells for secondary responses to histamine. | Journal of leukocyte biology 20030901 |
| Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. | European journal of biochemistry 20030901 |
| Serotonergic and histaminergic mechanisms involved in intralipid drinking? | Pharmacology, biochemistry, and behavior 20030901 |
| The effects of certain H(1)-antagonists on visual evoked potential in rats. | Brain research bulletin 20030830 |
| Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice. | American journal of physiology. Heart and circulatory physiology 20030801 |
| The effects of pyrilamine and cimetidine on mRNA C-fos expression and nociceptive flinching behavior in rats. | Anesthesia and analgesia 20030801 |
| Smooth muscle contraction induced by Indigofera dendroides leaf extracts may involve calcium mobilization via potential sensitive channels. | Phytotherapy research : PTR 20030801 |
| Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice. | European journal of pharmacology 20030620 |
| Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor. | The Journal of pharmacology and experimental therapeutics 20030601 |
| Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics. | European journal of pharmacology 20030530 |
| Histamine upregulates gene expression of endothelial nitric oxide synthase in human vascular endothelial cells. | Circulation 20030513 |
| Molecular characterization of specific H1-receptor agonists histaprodifen and its Nalpha-substituted analogues on bovine aortic H1-receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20030501 |
| Regulation by prostaglandin E2 and histamine of angiogenesis in inflammatory granulation tissue. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030501 |
| The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine. | Journal of pharmacological sciences 20030501 |
| Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine. | Bioorganic & medicinal chemistry letters 20030407 |
| Effect of antiemetic drugs on decrease in gastric emptying in experimental model of motion sickness in rats. | Acta pharmacologica Sinica 20030401 |
| Effect of histamine on the permeability of the nasal mucosa in vivo. | Acta oto-laryngologica 20030401 |
| Pro-cognitive effect of a selective histamine H1-receptor agonist, 2-(3-trifluoromethylphenyl)histamine, in the rat object recognition test. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401 |
| Thiomersal enhances the binding of histamine to the H1 receptor, but not histamine-stimulated inositol phosphate formation. | The Journal of pharmacy and pharmacology 20030401 |
| Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats. | European journal of pharmacology 20030328 |
| Light induces cortical activation and yawning in rats. | Behavioural brain research 20030318 |
| Pharmacologic effects of tobacco dust extract on isolated Guinea pig trachea. | Chest 20030301 |
| Analysis of the inflammatory response in the rat paw caused by the venom of Apis melifera bee. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030301 |
| Acid-induced mesenteric hyperemia in rats: role of CGRP, substance P, prostaglandin, adenosine, and histamine. | Digestive diseases and sciences 20030301 |
| Histaminergic modulation of the intact respiratory network of adult mice. | Pflugers Archiv : European journal of physiology 20030201 |
| Intrathecal histamine induces spinally mediated behavioral responses through tachykinin NK1 receptors. | Pharmacology, biochemistry, and behavior 20030101 |
| Histamine H1 receptors in the ventromedial hypothalamus mediate the anorectic action of the pancreatic hormone amylin. | Peptides 20030101 |
| IL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development. | Reproductive biology and endocrinology : RB&E 20030101 |
| Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels. | BMC neuroscience 20030101 |
| Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs. | BMC complementary and alternative medicine 20030101 |
| A role for histamine in cytokine modulation by the adenosine A(3) receptor agonist, 2-Cl-IB-MECA. | European journal of pharmacology 20021213 |
| Functional characterization of tachykinin NK1 receptors in the mouse uterus. | British journal of pharmacology 20021201 |
| Histamine inhibits the production of interferon-induced protein of 10 kDa in human squamous cell carcinoma and melanoma. | The Journal of investigative dermatology 20021201 |
| Permeation-enhancing effect of aloe-emodin anthrone on water-soluble and poorly permeable compounds in rat colonic mucosa. | Biological & pharmaceutical bulletin 20021201 |
| The role of histamine in dural vessel dilation. | Brain research 20021122 |
| Histamine H1-receptor modulation of inter-neuronal coupling among vasopressinergic neurons depends on nitric oxide synthase activation. | Brain research 20021115 |
| Histamine H1 receptors in rat dorsal raphe nucleus: pharmacological characterisation and linking to increased neuronal activity. | Brain research 20021108 |
| LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system. | Blood 20021101 |
| Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner. | Neuropharmacology 20021101 |
| Effects of histamine and opioid systems on memory retention of passive avoidance learning in rats. | European journal of pharmacology 20021004 |
| Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Enhancement of neutrophil infiltration in histidine decarboxylase-deficient mice. | Immunology 20021001 |
| Investigation on the influx transport mechanism of pentazocine at the blood-brain barrier in rats using the carotid injection technique. | Biological & pharmaceutical bulletin 20021001 |
| Murine tumor necrosis factor-alpha sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine. | Journal of neuroimmunology 20021001 |
| Effects of NMDA antagonist MK-801 on radial maze performance in Zucker rats. | Brain research 20020920 |
| Mediators of adenosine- and ovalbumen-induced bronchoconstriction of sensitized guinea-pig isolated airways. | European journal of pharmacology 20020906 |
| Cosensitivity of vagal mucosal afferents to histamine and 5-HT in the rat jejunum. | American journal of physiology. Gastrointestinal and liver physiology 20020901 |
| Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release. | Journal of immunology (Baltimore, Md. : 1950) 20020901 |
| Ligands for histamine H(3) receptors modulate cell proliferation and migration in rat oxyntic mucosa. | British journal of pharmacology 20020901 |
| Modulation of formalin-induced behaviors and edema by local and systemic administration of dextromethorphan, memantine and ketamine. | European journal of pharmacology 20020823 |
| Yawning/cortical activation induced by microinjection of histamine into the paraventricular nucleus of the rat. | Behavioural brain research 20020821 |
| Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice. | Journal of immunology (Baltimore, Md. : 1950) 20020815 |
| Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. | European journal of pharmacology 20020809 |
| Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery. | Clinical and experimental pharmacology & physiology 20020801 |
| Effects of histamine on the contractile and electrical activity in isolated lymphatic vessels of the guinea-pig mesentery. | British journal of pharmacology 20020801 |
| The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis. | The Journal of allergy and clinical immunology 20020801 |
| The antianaphylactic effects of Crinum glaucum aqueous extract. | Journal of ethnopharmacology 20020701 |
| Antinociceptive and smooth muscle contracting activities of the methanolic extract of Cassia tora leaf. | Journal of ethnopharmacology 20020701 |
| A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors. | The Journal of pharmacology and experimental therapeutics 20020701 |
| Histamine H(2) -like receptors in chick cerebral cortex: effects on cyclic AMP synthesis and characterization by [(3) H]tiotidine binding. | Journal of neurochemistry 20020601 |
| Modulation of the discriminative stimulus effects of cocaine and methamphetamine by the histaminergic system. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20020601 |
| Effect of the aqueous extract of African mistletoe, Tapinanthus sessilifolius (P. Beauv) van Tiegh leaf on gastrointestinal muscle activity. | Indian journal of experimental biology 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| GBR compounds and mepyramines as cocaine abuse therapeutics: chemometric studies on selectivity using grid independent descriptors (GRIND). | Journal of medicinal chemistry 20020411 |
| Neuropharmacological profile of a novel potential atypical antipsychotic drug Y-931 (8-fluoro-12-(4-methylpiperazin-1-yl)- 6H-[1]benzothieno[2,3-b][1,5] benzodiazepine maleate). | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020401 |
| Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats. | Acta pharmacologica Sinica 20020401 |
| Stimulation of protein kinase B and p70 S6 kinase by the histamine H1 receptor in DDT1MF-2 smooth muscle cells. | British journal of pharmacology 20020401 |
| Contractile response of horse deep dorsal penile vein to histamine. | International journal of impotence research 20020401 |
| Insulin-induced up-regulation of histamine H1-receptors. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401 |
| Mouse mammary epithelial cells bear histamine receptors. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401 |
| Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness. | International archives of allergy and immunology 20020401 |
| The initial inositol 1,4,5-trisphosphate response induced by histamine is strongly amplified by Ca(2+) release from internal stores in smooth muscle. | Cell calcium 20020401 |
| A study of cardiovascular effects of Azadirachta indica (neem) on isolated perfused heart preparations. | Indian journal of physiology and pharmacology 20020401 |
| Effects of the NMDA antagonist MK-801 on radial maze performance in histidine-deficient rats. | Life sciences 20020322 |
| Histamine excites GABAergic cells in the rat substantia nigra and ventral tegmental area in vitro. | Neuroscience letters 20020308 |
| The recovery of the neurally evoked secretory response of rat colonic mucosa after irradiation is independent of mast cells. | Radiation research 20020301 |
| Predicting the risk of Lyme disease: habitat suitability for Ixodes scapularis in the north central United States. | Emerging infectious diseases 20020301 |
| Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs. | Japanese journal of pharmacology 20020301 |
| Urothelium derived inhibitory factor and cross-talk among receptors in the trigone of the bladder of the pig. | The Journal of urology 20020201 |
| Orexins activate histaminergic neurons via the orexin 2 receptor. | Biochemical and biophysical research communications 20020201 |
| Role of mast cells in the development of pancreatitis-induced multiple organ dysfunction. | The British journal of surgery 20020201 |
| Neurochemical regulation of cough response to capsaicin in guinea-pigs. | Autonomic & autacoid pharmacology 20020201 |
| ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation. | European journal of pharmacology 20020118 |
| L-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles. | Biochimica et biophysica acta 20020102 |
| Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors. | Pharmacology, biochemistry, and behavior 20020101 |
| Impact of soil movement on carbon sequestration in agricultural ecosystems. | Environmental pollution (Barking, Essex : 1987) 20020101 |
| Effects of brain histamine on memory deficit induced by nucleus basalis-lesion in rats. | Acta pharmacologica Sinica 20020101 |
| Histamine-induced IL-6 and IL-8 production are differentially modulated by IFN-gamma and IL-4 in human keratinocytes. | Journal of dermatological science 20020101 |
| Antihistamine antinociception is mediated by Gi-protein activation. | Neuroscience 20020101 |
| Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones. | Neuroscience 20020101 |
| Topically applied aspirin decreases histamine-induced wheal and flare reactions in normal and SLS-inflamed skin, but does not decrease itch. A randomized, double-blind and placebo-controlled human study. | Acta dermato-venereologica 20020101 |
| Histochemical and biochemical studies on the secretory mechanisms of some glands of guinea-pigs treated with histamine. | Folia histochemica et cytobiologica 20020101 |
| Antiallergic anti-inflammatory effects of H1-antihistamines in humans. | Clinical allergy and immunology 20020101 |
| Suppression of spontaneous scratching in hairless rats by sedatives but not by antipruritics. | Skin pharmacology and applied skin physiology 20020101 |
| Does the neurotransmitter transporter underlie adaptation at a histaminergic photoreceptor synapse? | Visual neuroscience 20020101 |
| Identification of a histamine H4 receptor on human eosinophils--role in eosinophil chemotaxis. | Journal of receptor and signal transduction research 20020101 |
| Characterization of nasal obstruction in the allergic guinea pig using the forced oscillation method. | Journal of pharmacological and toxicological methods 20020101 |
| Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. | British journal of pharmacology 20011201 |
| Mechanism underlying histamine-induced intracellular Ca2+ movement in PC3 human prostate cancer cells. | Pharmacological research 20011201 |
| Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers. | Pharmacology & toxicology 20011201 |
| Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling. | Molecular pharmacology 20011101 |
| The kinetics, function, and regulation of P-selectin expressed by human brain microvessel endothelial cells in primary culture. | Microvascular research 20011101 |
| The role of central histaminergic neuron system as an anticonvulsive mechanism in developing brain. | Brain & development 20011101 |
| Standard treatment: the role of antihistamines. | The journal of investigative dermatology. Symposium proceedings 20011101 |
| Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. | Journal of neuro-oncology 20011101 |
| Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task. | Behavioural brain research 20011015 |
| Inhibitory effect of histamine on axonal transport in cultured mouse dorsal root ganglion neurons. | Neuroscience research 20011001 |
| Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells. | International immunopharmacology 20011001 |
| Preclinical comparison of ebastine and other second generation H1-antihistamines. | Pharmacology & toxicology 20011001 |
| Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors. | Cardiovascular research 20010901 |
| Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema. | Life sciences 20010817 |
| The effects of histamine and its antagonists on the cochlear microphonic and the compound action potential of the guinea pig. | Auris, nasus, larynx 20010801 |
| Histamine H(1) receptor activation inhibits the proliferation of human prostatic adenocarcinoma DU-145 cells. | The Prostate 20010801 |
| Activation of the p38 and p42/p44 mitogen-activated protein kinase families by the histamine H(1) receptor in DDT(1)MF-2 cells. | British journal of pharmacology 20010801 |
| Effects of vasopressin on histamine H(1) receptor antagonist-induced spatial memory deficits in rats. | European journal of pharmacology 20010706 |
| Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. | British journal of pharmacology 20010701 |
| Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats. | Acta pharmacologica Sinica 20010701 |
| Mechanisms of histamine-induced intracellular Ca2+ release and extracellular Ca2+ entry in MG63 human osteosarcoma cells. | Biochemical pharmacology 20010615 |
| The H3 receptor is involved in cholecystokinin inhibition of food intake in rats. | Life sciences 20010615 |
| Pharmacological characterization of the rat paw edema induced by Bothrops lanceolatus (Fer de lance) venom. | Toxicon : official journal of the International Society on Toxinology 20010601 |
| Pharmacologic properties of brewery dust extracts in vitro. | Chest 20010601 |
| Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon. | Digestive diseases and sciences 20010601 |
| Tachykinin-induced bronchoconstriction in sheep is NK-1 receptor mediated and exhibits tachyphylaxis. | Respirology (Carlton, Vic.) 20010601 |
| Activation of histamine H3 receptors inhibits renal noradrenergic neurotransmission in anesthetized dogs. | American journal of physiology. Regulatory, integrative and comparative physiology 20010501 |
| VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities. | Japanese journal of pharmacology 20010501 |
| Localization of neurotensin NTS2 receptors in rat brain, using. | Neuroreport 20010417 |
| Beta(3)-adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthetized rhesus monkeys. | The Journal of pharmacology and experimental therapeutics 20010401 |
| Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve. | British journal of pharmacology 20010401 |
| Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate. | Pharmacological research 20010401 |
| Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2. | European journal of clinical pharmacology 20010401 |
| Comparison of cedar pollen-induced allergic rhinitis in passively and actively sensitized guinea pigs. | Japanese journal of pharmacology 20010401 |
| Effect of clobenpropit on regional cerebral blood flow in rat hippocampus. | Acta pharmacologica Sinica 20010401 |
| Dopaminergic effects of histamine administration in the nucleus accumbens and the impact of H1-receptor blockade. | Neuropharmacology 20010301 |
| Regulation of parasympathetic neurons by mast cells and histamine in the guinea pig heart. | Autonomic neuroscience : basic & clinical 20010220 |
| Involvement of central histaminergic neurons in polypnea induced by hyperthermia in rabbits. | Neuroscience letters 20010202 |
| Characterization of a novel cationic drug transporter in human retinal pigment epithelial cells. | The Journal of pharmacology and experimental therapeutics 20010201 |
| Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. | Molecular pharmacology 20010201 |
| Histamine alters gene expression in cultured human nasal epithelial cells. | The Journal of allergy and clinical immunology 20010201 |
| H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways. | Naunyn-Schmiedeberg's archives of pharmacology 20010201 |
| Characterization of histamine-induced increases in intracellular free Ca2+ concentrations in Chang liver cells. | Journal of receptor and signal transduction research 20010201 |
| Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. | British journal of pharmacology 20010101 |
| The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception. | Neuroscience 20010101 |
| Role of mast cells in zymosan-induced peritoneal inflammation in Balb/c and mast cell-deficient WBB6F1 mice. | Journal of leukocyte biology 20010101 |
| Pharmacological characterization of cyclosporine A-induced kaolin intake in rats. | Pharmacology, biochemistry, and behavior 20010101 |
| Role of L-arginine/nitric oxide pathway in the antinociceptive activities of morphine and mepyramine in mice. | Arzneimittel-Forschung 20010101 |
| QSAR study on binding affinity of PATs (rodenticides) to the [3H]-mepyramine-labelled H1 receptor in rat and guinea pig brain. | SAR and QSAR in environmental research 20010101 |
| Effects of histamine on phosphoinositide metabolism in chick cerebral cortex. | Polish journal of pharmacology 20010101 |
| Changes in blood pressure in the rat induced by the venom extract from a sea anemone-Bunodosoma cavernata. | African journal of medicine and medical sciences 20010101 |
| Mechanism responsible for epileptogenic activity by first-generation H1-antagonists in rats. | Brain research 20001222 |
| Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain. | Journal of neurochemistry 20000801 |
| Antiamnesic effect of metoprine and of selective histamine H(1) receptor agonists in a modified mouse passive avoidance test. | Neuroscience letters 20000707 |
| A novel phenylaminotetralin (PAT) recognizes histamine H1 receptors and stimulates dopamine synthesis in vivo in rat brain. | Brain research 20000103 |
| Effect of interleukin-1beta on the ascending and descending reflex in rat small intestine. | European journal of pharmacology 19981023 |
| Therapeutic doses of theophylline exert proconvulsant effects in developing mice. | Brain & development 19970901 |
| G proteins of the Gq family couple the H2 histamine receptor to phospholipase C. | Molecular endocrinology (Baltimore, Md.) 19961201 |
| Contribution of mast cell mediators to alterations in macrophage function after malathion administration. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19960901 |
| Histamine-1 receptor blockade does not prevent nitroglycerin induced migraine. Support for the NO-hypothesis of migraine. | European journal of clinical pharmacology 19960101 |
| Dose-dependent mediation of leukotriene D4-induced airway microvascular leakage and bronchoconstriction in the guinea pig. | Prostaglandins, leukotrienes, and essential fatty acids 19950601 |
| Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene. | European journal of biochemistry 19940901 |
| A role for endogenous histamine in interleukin-8-induced neutrophil infiltration into mouse air-pouch: investigation of the modulatory action of systemic and local dexamethasone. | British journal of pharmacology 19940701 |
| The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis. | Pulmonary pharmacology 19940401 |
| Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. | American journal of respiratory and critical care medicine 19940101 |
| Canine in vivo tracheal chemotaxis of eosinophils to antigen in sensitized dogs: inhibition by a steroid, a systemic lazaroid U-78517F, and several topical H1 antihistamines. | The American review of respiratory disease 19920901 |
| Capsaicin-induced hyperemia in the stomach: possible contribution of mast cells. | The American journal of physiology 19920801 |
| Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin. | The British journal of dermatology 19920201 |
| Decreased histamine H1 receptors in the frontal cortex of brains from patients with chronic schizophrenia. | Biological psychiatry 19910815 |
| Correlation of brain levels of 9-amino-1,2,3,4-tetrahydroacridine (THA) with neurochemical and behavioral changes. | European journal of pharmacology 19891128 |
| Solubilization, characterization and partial purification of [3H]mepyramine-binding protein, a possible histamine H1 receptor, from rat liver membrane. | Japanese journal of pharmacology 19880201 |
| Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay. | Japanese journal of pharmacology 19870301 |
| Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist. | Agents and actions 19870201 |
| Regulation of membrane histamine H1-receptor binding sites by guanine nucleotides, mono- and divalent cations. | Agents and actions 19860401 |
| Antagonism of drug-induced yawning and penile erections in rats. | European journal of pharmacology 19860318 |
| H1-histamine receptors on human astrocytoma cells. | Molecular pharmacology 19860201 |
| Effects of histamine antagonists on noradrenaline-stimulated blood flow and oxygen consumption of brown adipose tissue in the rat. | Pflugers Archiv : European journal of physiology 19841101 |
| Specific binding of [3H]mepyramine to histamine H1-receptors in vascular smooth muscle membranes. | Agents and actions 19830401 |
| The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol. | Polish journal of pharmacology and pharmacy 19830101 |
| Fibrin-derived vasoactive peptides release histamine. | International journal of microcirculation, clinical and experimental 19830101 |
| Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication. | American journal of diseases of children (1960) 19780101 |
| Cholinesterase inhibition by phenothiazine and nonphenothiazine antihistaminics: analysis of its postulated role in synergizing organophosphate toxicity. | Toxicology and applied pharmacology 19750201 |
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