200,000+ products from a single source!
sales@angenechem.com
90943-32-1 | 4-PYRIDIN-2-YLBUTANAL
CAS No: 90943-32-1 Catalog No: AG00GYH3 MDL No:
Product Description
Catalog Number:
AG00GYH3
Chemical Name:
4-PYRIDIN-2-YLBUTANAL
CAS Number:
90943-32-1
IUPAC Name:
4-pyridin-2-ylbutanal
InChI:
InChI=1S/C9H11NO/c11-8-4-2-6-9-5-1-3-7-10-9/h1,3,5,7-8H,2,4,6H2
InChI Key:
ANDQQLPIJOOMAZ-UHFFFAOYSA-N
Properties
Complexity:
114
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
149.084g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
149.193g/mol
Monoisotopic Mass:
149.084g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
30A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6
Literature
| Title | Journal |
|---|---|
| Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice. | Chemical research in toxicology 20121015 |
| Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli. | Chemical research in toxicology 20111121 |
| The role of tobacco-derived carcinogens in pancreas cancer. | ISRN oncology 20110101 |
| Formation, repair, and genotoxic properties of bulky DNA adducts formed from tobacco-specific nitrosamines. | Journal of nucleic acids 20100101 |
| Formation and repair of tobacco carcinogen-derived bulky DNA adducts. | Journal of nucleic acids 20100101 |
| The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines. | Chemical research in toxicology 20090817 |
| Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. | Drug metabolism and disposition: the biological fate of chemicals 20090601 |
| Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. | Chemical research in toxicology 20090501 |
| Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine. | Chemical research in toxicology 20090501 |
| Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. | Chemical research in toxicology 20090201 |
| Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. | Chemical research in toxicology 20080701 |
| Repair of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA pyridyloxobutylation by nucleotide excision repair. | Cancer letters 20080218 |
| Investigation of the reaction of myosmine with sodium nitrite in vitro and in rats. | Chemical research in toxicology 20070301 |
| Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. | Chemical research in toxicology 20070201 |
| Analysis of pyridyloxobutyl DNA adducts in F344 rats chronically treated with (R)- and (S)-N'-nitrosonornicotine. | Chemical research in toxicology 20070201 |
| Synthesis of 4-[2-aminoethyl(nitrosamino)]-1-pyridin-3-yl-butan-1-one, a new NNK hapten for the induction of N-nitrosamine-specific antibodies. | Bioconjugate chemistry 20070101 |
| Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. | Chemical research in toxicology 20060501 |
| Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. | Chemical research in toxicology 20050601 |
| Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA. | Chemical research in toxicology 20040501 |
| The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants. | Chemical research in toxicology 20040301 |
| Nucleophilic reactions between thiols and a tobacco specific nitrosamine metabolite, 4-hydroxy-1-(3-pyridyl)-1-butanone. | Chemical research in toxicology 20030501 |
| K-ras gene sequence effects on the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-DNA adducts. | Chemical research in toxicology 20030401 |
| The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice. | Chemical research in toxicology 20030101 |
| Characterization and mapping of DNA damage induced by reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) at nucleotide resolution in human genomic DNA. | Journal of molecular biology 20011026 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.