CAS 9001-73-4 | Papain | CAS Number 9001-73-4

Title	Journal
Use of viscera extract from hybrid catfish (Clarias macrocephalus × Clarias gariepinus) for the production of protein hydrolysate from toothed ponyfish (Gazza minuta) muscle.	Food chemistry 20130115
Treatment of Phaeodactylum tricornutum cells with papain facilitates lipid extraction.	Journal of biotechnology 20121130
Studies on the chemical modification of goat liver cystatin and the effect on its anti-papain inhibitory activity.	Journal of fluorescence 20121101
A novel in vivo rabbit model of abdominal aortic aneurysm induced by periarterial incubation of papain.	Journal of vascular and interventional radiology : JVIR 20121101
Enhancement of protease-induced IL-6 release in monocytic U-937 cells by phorbol-12-myristate-13-acetate.	Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001
Fluorescence spectroscopic analysis of the interaction of papain with ionic liquids.	Applied biochemistry and biotechnology 20121001
Purification of chicken breast protein hydrolysate and analysis of its antioxidant activity.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001
Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121001
Cystatin B homolog from rock bream Oplegnathus fasciatus: genomic characterization, transcriptional profiling and protease-inhibitory activity of recombinant protein.	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120901
Chondroprotective and anti-inflammatory effects of sesamin.	Phytochemistry 20120801
Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata.	Journal of agricultural and food chemistry 20120801
Purification and identification of antioxidant peptides from egg white protein hydrolysate.	Amino acids 20120701
Cryptostatin, a chagasin-family cysteine protease inhibitor of Cryptosporidium parvum.	Parasitology 20120701
Papain-specific activating esters in aqueous dipeptide synthesis.	Chembiochem : a European journal of chemical biology 20120618
Optimisation of hydrolysis of purple sea urchin (Strongylocentrotus nudus) gonad by response surface methodology and evaluation of in vitro antioxidant activity of the hydrolysate.	Journal of the science of food and agriculture 20120601
Influence of incubation conditions on hydrolysis efficiency and iodine enrichment in baker's yeast.	Biological trace element research 20120601
Purification of papain using reactive green 5 attached supermacroporous monolithic cryogel.	Applied biochemistry and biotechnology 20120601
Reactivity of nitroxyl-derived sulfinamides.	Biochemistry 20120522
Optimization of a microwave-coupled enzymatic digestion process to prepare peanut peptides.	Molecules (Basel, Switzerland) 20120511
C1A cysteine-proteases and their inhibitors in plants.	Physiologia plantarum 20120501
Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity.	The Journal of allergy and clinical immunology 20120501
Aggregation and inactivation of pancreatic cystatin by riboflavin-derived singlet oxygen and flavin triplet state: polyphenols as preventive agents.	Journal of biochemical and molecular toxicology 20120501
A dityrosine-based substrate for a protease assay: application for the selective assessment of papain and chymopapain activity.	Analytica chimica acta 20120420
Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.	Plant physiology 20120401
3-aminopiperidine-based peptide analogues as the first selective noncovalent inhibitors of the bacterial cysteine protease IdeS.	Journal of medicinal chemistry 20120322
A potent, versatile disulfide-reducing agent from aspartic acid.	Journal of the American Chemical Society 20120307
Enzyme catalytic promiscuity: The papain-catalyzed Knoevenagel reaction.	Biochimie 20120301
Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets.	Journal of medicinal food 20120301
Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody.	Pharmaceutical research 20120101
Assessment of the angiotensin-I-converting enzyme (ACE-I) inhibitory and antioxidant activities of hydrolysates of bovine brisket sarcoplasmic proteins produced by papain and characterisation of associated bioactive peptidic fractions.	Meat science 20120101
Rodent retinal ganglion cell cultures.	Methods in molecular biology (Clifton, N.J.) 20120101
Clinical evaluation of caries removal in primary teeth using conventional, chemomechanical and laser technique: an in vivo study.	The journal of contemporary dental practice 20120101
Production of defatted palm kernel cake protein hydrolysate as a valuable source of natural antioxidants.	International journal of molecular sciences 20120101
Isolation and gene expression analysis of a papain-type cysteine protease in thermogenic skunk cabbage (Symplocarpus renifolius).	Bioscience, biotechnology, and biochemistry 20120101
The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.	Archives of biochemistry and biophysics 20111215
Identification of interactions involved in the generation of nucleophilic reactivity and of catalytic competence in the catalytic site Cys/His ion pair of papain.	Biochemistry 20111213
Free radical scavenging and angiotensin-I converting enzyme inhibitory peptides from Pacific cod (Gadus macrocephalus) skin gelatin.	International journal of biological macromolecules 20111201
Interactions of nanobubbles with bovine serum albumin and papain films on gold surfaces.	Biointerphases 20111201
Efficacy of chitooligosaccharides for the management of diabetes in alloxan induced mice: a correlative study with antihyperlipidemic and antioxidative activity.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120
Development of a new experimental model of saccular aneurysm by intra-arterial incubation of papain in rabbits.	Neuroradiology 20111101
3A4, a new potential target for B and myeloid lineage leukemias.	Journal of drug targeting 20111101
Immobilization and stabilization of papain on poly(hydroxyethyl methacrylate-ethylenglycol dimethacrylate) beads grafted with epoxy functional polymer chains via surface-initiated-atom transfer radical polymerization (SI-ATRP).	Bioresource technology 20111101
Metal ion mediated self-assembly directed formation of protein arrays.	Biomacromolecules 20111010
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.	Nature immunology 20111009
Respiratory mechanics do not always mirror pulmonary histological changes in emphysema.	Clinics (Sao Paulo, Brazil) 20111001
Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.	Chembiochem : a European journal of chemical biology 20110919
Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration.	Organic & biomolecular chemistry 20110821
Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts--an in vitro study.	International journal of dental hygiene 20110801
Crystal structure of tarocystatin-papain complex: implications for the inhibition property of group-2 phytocystatins.	Planta 20110801
Keratin film made of human hair as a nail plate model for studying drug permeation.	European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801
Antioxidant and antiproliferative activities of loach ( Misgurnus anguillicaudatus ) peptides prepared by papain digestion.	Journal of agricultural and food chemistry 20110727
Isolation and characterization of three novel peptides from casein hydrolysates that stimulate the growth of mixed cultures of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus.	Journal of agricultural and food chemistry 20110713
Ribosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies.	Molecular biotechnology 20110701
The nonstructural protein 1 papain-like cysteine protease was necessary for porcine reproductive and respiratory syndrome virus nonstructural protein 1 to inhibit interferon-β induction.	DNA and cell biology 20110601
Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events.	Journal of immunology (Baltimore, Md. : 1950) 20110601
A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.	Journal of microbiology and biotechnology 20110601
Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity.	Biochemical and biophysical research communications 20110513
The mechanism of papain inhibition by peptidyl aldehydes.	Proteins 20110301
Molecular cloning and biochemical characterization of a novel cystatin from Hevea rubber latex.	Plant physiology and biochemistry : PPB 20110301
Metastability of papain and the molecular mechanism for its sequential acid-denaturation.	The protein journal 20110301
Morphology and microtensile bond strength of adhesive systems to in situ-formed caries-affected dentin after the use of a papain-based chemomechanical gel method.	American journal of dentistry 20110201
Backbone degradable multiblock N-(2-hydroxypropyl)methacrylamide copolymer conjugates via reversible addition-fragmentation chain transfer polymerization and thiol-ene coupling reaction.	Biomacromolecules 20110110
Surface Plasmon Resonance Imaging (SPRI) sensor for cystatin determination based on immobilized papain.	Protein and peptide letters 20110101
PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway.	PloS one 20110101
Sodium tetrathionate effect on papain purification from different Carica papaya latex crude extracts.	Preparative biochemistry & biotechnology 20110101
Papain-like proteases of Staphylococcus aureus.	Advances in experimental medicine and biology 20110101
Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.	PloS one 20110101
Development of enteric submicron particle formulation of papain for oral delivery.	International journal of nanomedicine 20110101
Kinetically controlled enzymatic synthesis of dipeptide precursor of L-alanyl-L-glutamine.	Biotechnology and applied biochemistry 20110101
An evaluation of different caries removal techniques in primary teeth: a comparitive clinical study.	The Journal of clinical pediatric dentistry 20110101
Removal of mercury (II) from aqueous solution using papain immobilized on alginate bead: optimization of immobilization condition and modeling of removal study.	Bioresource technology 20101201
Reduction of benzaldehyde catalyzed by papain-based semisynthetic enzymes.	Applied biochemistry and biotechnology 20101101
High level production of bioactive di- and tri-tyrosine peptides by protease-catalyzed reactions.	Journal of biotechnology 20101101
The effect of various wound dressings on the activity of debriding enzymes.	Advances in skin & wound care 20101001
A distinct subfamily of papain-like cystein proteinases regulated by senescence and stresses in Glycine max.	Journal of plant physiology 20100901
Plant cysteine proteases that evoke itch activate protease-activated receptors.	The British journal of dermatology 20100901
Identification and characterization of a Cystatin gene from Chinese mitten crab Eriocheir sinensis.	Fish & shellfish immunology 20100901
Structural and mechanistic insights into a novel non-competitive Kunitz trypsin inhibitor from Adenanthera pavonina L. seeds with double activity toward serine- and cysteine-proteinases.	Journal of molecular graphics & modelling 20100901
Optimization of hydrolysis conditions for the production of antioxidant peptides from fish gelatin using response surface methodology.	Journal of food science 20100801
Isolation, structure, and functional elucidation of a modified pentapeptide, cysteine protease inhibitor (CPI-2081) from Streptomyces species 2081 that exhibit inhibitory effect on cancer cell migration.	Journal of medicinal chemistry 20100722
The effects of different maceration techniques on nuclear DNA amplification using human bone.	Journal of forensic sciences 20100701
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.	Nature immunology 20100701
Mesoporous organosilicas with ultra-large pores: mesophase transformation and bioadsorption properties.	Journal of colloid and interface science 20100601
Improving thermostability of papain through structure-based protein engineering.	Protein engineering, design & selection : PEDS 20100601
Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway.	Journal of Korean medical science 20100601
Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules.	European journal of medicinal chemistry 20100501
A study of the efficacy of cleansers for acne vulgaris.	The Journal of dermatological treatment 20100501
Effect of neutrase, alcalase, and papain hydrolysis of whey protein concentrates on iron uptake by Caco-2 cells.	Journal of agricultural and food chemistry 20100428
Effects of a novel pathogenesis-related class 10 (PR-10) protein from Crotalaria pallida Roots with papain inhibitory activity against root-knot nematode Meloidogyne incognita.	Journal of agricultural and food chemistry 20100414
Behavior of papain in mixed micelles of anionic-cationic surfactants having similar tails and dissimilar head groups.	Journal of colloid and interface science 20100401
Crystal structure of human cystatin C stabilized against amyloid formation.	The FEBS journal 20100401
Even-numbered peptides from a papain hydrolysate of silk fibroin.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315
Cysteine enhances activity and stability of immobilized papain.	Amino acids 20100301
In silico analysis of sequential, structural and functional diversity of wheat cystatins and its implication in plant defense.	Genomics, proteomics & bioinformatics 20100301
[Enzymatic production of oral nutritional liquid from oyster].	Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100301
Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule.	Analytical biochemistry 20100201
[Fluorescence spectra analysis of papain structure treated by dynamic high pressure microfluidization in low pressure ranges].	Guang pu xue yu guang pu fen xi = Guang pu 20100201
Method for studying immunoglobulin G binding on hydrophobic surfaces.	Langmuir : the ACS journal of surfaces and colloids 20100119
Immobilization of modified papain with anhydride groups on activated cotton fabric.	Applied biochemistry and biotechnology 20100101
The importance of correct protein concentration for kinetics and affinity determination in structure-function analysis.	Journal of visualized experiments : JoVE 20100101
Purification and in situ immobilization of papain with aqueous two-phase system.	PloS one 20100101
[The use of enzymatic hydrolysis for isolation of barbituric acid derivatives from blood (as exemplified by phenobarbital and barbamyl)].	Sudebno-meditsinskaia ekspertiza 20100101
Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain.	Proteins 20091201
A salivary cystatin, HlSC-1, from the ixodid tick Haemaphysalis longicornis play roles in the blood-feeding processes.	Parasitology research 20091201
Dipeptide-derived nitriles containing additional electrophilic sites: potentially irreversible inhibitors of cysteine proteases.	Journal of enzyme inhibition and medicinal chemistry 20091201
Two routes for production and purification of Fab fragments in biopharmaceutical discovery research: Papain digestion of mAb and transient expression in mammalian cells.	Protein expression and purification 20091001
Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.	Journal of pharmaceutical sciences 20091001
Profiling of calpain activity with a series of FRET-based substrates.	Biochimica et biophysica acta 20091001
Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats.	Arthritis and rheumatism 20091001
Sensory crispness of crispy rolls: effect of formulation, storage conditions, and water distribution in the crust.	Journal of food science 20091001
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.	Analytical biochemistry 20090915
Effects of sodium ferulate on human osteoarthritic chondrocytes and osteoarthritis in rats.	Clinical and experimental pharmacology & physiology 20090901
Proteomic identification of an MHC-binding peptidome from pancreas and breast cancer cell lines.	Molecular immunology 20090901
Hydrolytic properties and substrate specificity of the foot-and-mouth disease leader protease.	Biochemistry 20090825
Polyrotaxane composed of poly-L-lactide and alpha-cyclodextrin exhibiting protease-triggered hydrolysis.	Biomacromolecules 20090810
Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.	The Journal of organic chemistry 20090807
eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain.	Journal of inorganic biochemistry 20090801
Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera.	The FEBS journal 20090801
Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2.	Journal of immunology (Baltimore, Md. : 1950) 20090715
Sulfonation of papain-treated chitosan and its mechanism for anticoagulant activity.	Carbohydrate research 20090706
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response.	Nature immunology 20090701
Antithrombotic papain-hydrolyzed peptides isolated from pork meat.	Thrombosis research 20090301
Production and recovery of recombinant propapain with high yield.	Phytochemistry 20090301
Evaluation of alpha,beta-unsaturated ketone-based probes for papain-family cysteine proteases.	Bioorganic & medicinal chemistry 20090201
Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases.	The FEBS journal 20090201
Close proximity of myosin loop 3 to troponin determined by triangulation of resonance energy transfer distance measurements.	Biochemistry 20090120
Enantioselective reductive amination of alpha-keto acids by papain-based semisynthetic enzyme.	Biochemistry. Biokhimiia 20090101
Biocompatibility analysis of chemomechanical caries removal material Papacárie on cultured fibroblasts and subcutaneous tissue.	Journal of dentistry for children (Chicago, Ill.) 20090101
Two Kunitz-type inhibitors with activity against trypsin and papain from Pithecellobium dumosum seeds: purification, characterization, and activity towards pest insect digestive enzyme.	Protein and peptide letters 20090101
Biochemical and PMF MALDI-TOF analyses of two novel papain-like plant proteinases.	Protein and peptide letters 20090101
Antioxidant activities of hydrolysates of Arca subcrenata prepared with three proteases.	Marine drugs 20081201
Development of immunoaffinity restricted access media for rapid extractions of low-mass analytes.	Analytical chemistry 20081115
Identifying and characterizing the biological targets of metallotherapeutics: Two approaches using Au(I)-protein interactions as model systems.	Analytical biochemistry 20081101
Hormone induced changes in lactase glycosylation in developing rat intestine.	Molecular and cellular biochemistry 20081101
A pulse--radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity.	Free radical biology & medicine 20081101
[Gastric bezoar as complication of gastric banding. Report of one case].	Revista medica de Chile 20081101
Characterization of inhibitory mechanism and antifungal activity between group-1 and group-2 phytocystatins from taro (Colocasia esculenta).	The FEBS journal 20081001
Peptidyl epoxides extended in the P' direction as cysteine protease inhibitors: effect on affinity and mechanism of inhibition.	Bioorganic & medicinal chemistry 20081001
[The enzyme papain in industry and food causes allergic sensitization].	Ugeskrift for laeger 20080929
Two cysteine proteinase inhibitors from Arabidopsis thaliana, AtCYSa and AtCYSb, increasing the salt, drought, oxidation and cold tolerance.	Plant molecular biology 20080901
Plant cysteine proteinases: evaluation of the pharmacological activity.	Phytochemistry 20080901
Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.	Nature chemical biology 20080901
Internalization of cystatin C in human cell lines.	The FEBS journal 20080901
Fluorescence of primary dentine after chemomechanical and conventional rotary excavation.	European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 20080901
Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.	The Journal of biological chemistry 20080815
Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L.	Molecular pharmacology 20080701
Hybrid protease inhibitors for pest and pathogen control--a functional cost for the fusion partners?	Plant physiology and biochemistry : PPB 20080701
Molecular docking of cathepsin L inhibitors in the binding site of papain.	Journal of chemical information and modeling 20080701
[Prokaryotic expression of OC-IdeltaD86 (Oryzacystatin-IdeltaD86) gene and analysis of its activity].	Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080701
Characterization of a three-component coupling reaction on proteins by isotopic labeling and nuclear magnetic resonance spectroscopy.	Journal of the American Chemical Society 20080618
Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype.	Bioorganic & medicinal chemistry letters 20080615
Isolation and characterization of a cDNA encoding a papain-like cysteine protease from alfalfa.	DNA sequence : the journal of DNA sequencing and mapping 20080601
Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.	Biochimica et biophysica acta 20080601
Mechanism for stabilization of the molten globule state of papain by sodium n-alkyl sulfates: spectroscopic and calorimetric approaches.	Journal of colloid and interface science 20080601
Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion.	Analytical chemistry 20080601
A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture.	Virology 20080510
Stabilization of scleral collagen by glycerol aldehyde cross-linking.	Biochimica et biophysica acta 20080501
Glycosylation profiling of a therapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer.	Analytical biochemistry 20080415
Free radical scavenging activity of a novel antioxidative peptide purified from hydrolysate of bullfrog skin, Rana catesbeiana Shaw.	Bioresource technology 20080401
Separation and characterization of the colored material from sugarcane molasses.	Chemosphere 20080401
Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.	Biochemistry 20080219
Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria.	The FEBS journal 20080201
The nsp1alpha and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis.	The Journal of general virology 20080201
Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae.	Microbiological research 20080101
2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation.	Molecular cancer therapeutics 20080101
Plant proteases: from phenotypes to molecular mechanisms.	Annual review of plant biology 20080101
Bovine explant model of degeneration of the intervertebral disc.	BMC musculoskeletal disorders 20080101
Evaluation of residual dentin after conventional and chemomechanical caries removal using SEM.	The Journal of clinical pediatric dentistry 20080101
Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.	Angewandte Chemie (International ed. in English) 20080101
Enzymatic wound debridement.	Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20080101
Strategies for addressing restorative challenges in HIV-infected children.	Journal of dentistry for children (Chicago, Ill.) 20080101
Chemo-mechanical removal of caries in an adolescent patient using a papain gel: case report.	The Journal of clinical pediatric dentistry 20080101
Papain adulteration in 11-nor-Delta9-tetrahydrocannabinol- 9-carboxylic acid-positive urine samples.	Journal of analytical toxicology 20080101
[Chemoenzymatic synthesis of new fluorogenous substrates for cysteine proteases of the papain family].	Bioorganicheskaia khimiia 20080101
Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders.	Molecular plant pathology 20080101
[Isolation of blood caffeine as a model substance by enzymatic hydrolysis].	Sudebno-meditsinskaia ekspertiza 20080101
Albumin competitively inhibits glycation of less abundant proteins.	Protein and peptide letters 20080101
[Study of therapeutic effect and mechanism of Sihuang powder treating acute synovitis in experimental rabbit induced by papain injection].	Zhongguo gu shang = China journal of orthopaedics and traumatology 20080101
Inhibition of ice crystal growth in ice cream mix by gelatin hydrolysate.	Journal of agricultural and food chemistry 20071226
GrpE N-terminal domain contributes to the interaction with Dnak and modulates the dynamics of the chaperone substrate binding domain.	Journal of molecular biology 20071207
[Fluorescence spectra analysis of papain treated by pulsed electric field].	Guang pu xue yu guang pu fen xi = Guang pu 20071201
Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.	Bioorganic & medicinal chemistry 20071115
Mechanism of solvent induced thermal stabilization of papain.	International journal of biological macromolecules 20071001
Physicochemical and bitterness properties of enzymatic pea protein hydrolysates.	Journal of food science 20071001
Pore-size tunable mesoporous zirconium organophosphonates with chiral L-proline for enzyme adsorption.	Inorganic chemistry 20070917
Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.	Journal of chromatography. A 20070914
Preparation of hydrophilic polyhydroxyalkyl glutamine crosslinked films and its biodegradability.	Journal of biomaterials applications 20070901
Purification of a cysteine protease inhibitor from larval hemolymph of the tobacco hornworm (Manduca sexta) and functional expression of the recombinant protein.	Insect biochemistry and molecular biology 20070901
Enzymatic hydrolysis of heated whey: iron-binding ability of peptides and antigenic protein fractions.	Journal of dairy science 20070901
Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.	Neoplasia (New York, N.Y.) 20070901
Domain organization and movements in heavy metal ion pumps: papain digestion of CopA, a Cu+-transporting ATPase.	The Journal of biological chemistry 20070831
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.	Bioorganic & medicinal chemistry 20070801
The catalytic mode of cysteine proteinases of papain (C1) family.	Bioresource technology 20070701
Cloning and characterisation of the Anisakis simplex allergen Ani s 4 as a cysteine-protease inhibitor.	International journal for parasitology 20070701
Effect of polyethylene glycols on the function and structure of thiol proteases.	Journal of biochemistry 20070701
Carboxy terminal extended phytocystatins are bifunctional inhibitors of papain and legumain cysteine proteinases.	FEBS letters 20070626
Application of recombinant chum salmon cystatin to Alaska pollock (Theragra chalcogramma) surimi to prevent gel weakening.	Journal of food science 20070601
Multiple domains of endopin 2A for serpin cross-class inhibition of papain.	Archives of biochemistry and biophysics 20070515
Effects of knee injection on skeletal muscle metabolism and contractile force in rats.	Osteoarthritis and cartilage 20070501
Structure of the mexicain-E-64 complex and comparison with other cysteine proteases of the papain family.	Acta crystallographica. Section D, Biological crystallography 20070501
Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.	Chemistry & biology 20070501
[Resonance scattering spectral assay of papain enzymatic activity with sodium dodecyl benzene sulfonate].	Guang pu xue yu guang pu fen xi = Guang pu 20070501
Active fragments of the antihemorrhagic protein HSF from serum of habu (Trimeresurus flavoviridis).	Toxicon : official journal of the International Society on Toxinology 20070401
Bicyclic carbamates as inhibitors of papain-like cathepsin proteases.	Bioorganic & medicinal chemistry letters 20070301
Effect of both ultraviolet B irradiation and histamine receptor function on allergic responses to an inhaled antigen.	Journal of immunology (Baltimore, Md. : 1950) 20070301
Characterization of hydrolysates derived from enzymatic hydrolysis of wheat gluten.	Journal of food science 20070301
Cysteine-specific, covalent anchoring of transition organometallic complexes to the protein papain from Carica papaya.	Chembiochem : a European journal of chemical biology 20070122
Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo.	Parasitology 20070101
Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.	Molecular and biochemical parasitology 20070101
A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease.	Plant physiology 20070101
A silicone-based controlled-release device for accelerated proteolytic debridement of wounds.	Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101
Heterogeneity of proteinase inhibitors in the water-soluble organic matrix from the oyster nacre.	Marine biotechnology (New York, N.Y.) 20070101
Aerosol probes of emphysema progression in dogs treated with all trans retinoic acid--an exploratory study.	Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20070101
Chemical versus conventional caries removal techniques in primary teeth: a microhardness study.	The Journal of clinical pediatric dentistry 20070101
Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles.	Bioconjugate chemistry 20070101
Fc glycans terminated with N-acetylglucosamine residues increase antibody resistance to papain.	Biotechnology progress 20070101
The Surface Plasmon Resonance Imaging sensor for papain based on immobilized cystatin.	Protein and peptide letters 20070101
Purification and characterization of a trypsin-papain inhibitor from Pithecelobium dumosum seeds and its in vitro effects towards digestive enzymes from insect pests.	Plant physiology and biochemistry : PPB 20070101
Influence of papain urea copper chlorophyllin on wound matrix remodeling.	Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101
[Ubiquitin causes selective increase in the sensitivity of rat brain mitochondrial monoamine oxidases to various proteases].	Biomeditsinskaia khimiia 20070101
In vitro study of the effectiveness of different dressings for debriding fibrin in blood clots from horses.	The Veterinary record 20061118
Kosmotropic salt activation and substrate specificity of poliovirus protease 3C.	Biochemistry 20061003
Meat tenderizing effect of injecting encapsulated Ca2+ in liposome into rabbit before slaughter.	Bioscience, biotechnology, and biochemistry 20061001
Characterization of partially folded intermediates of papain in presence of cationic, anionic, and nonionic detergents at low pH.	Biopolymers 20060901
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols.	The Biochemical journal 20060901
Molecular cloning, sequencing, expression of Chinese sturgeon cystatin in yeast Pichia pastoris and its proteinase inhibitory activity.	Journal of biotechnology 20060901
Antioxidant activity of zein hydrolysates in a liposome system and the possible mode of action.	Journal of agricultural and food chemistry 20060809
Dipeptide vinyl sultams: synthesis via the Wittig-Horner reaction and activity against papain, falcipain-2 and Plasmodium falciparum.	Bioorganic & medicinal chemistry letters 20060801
Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.	Plant physiology 20060701
Recombinant expression, purification, and functional analysis of two novel cystatins from sugarcane (Saccharum officinarum).	Protein expression and purification 20060601
Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.	Chembiochem : a European journal of chemical biology 20060601
High-resolution complex of papain with remnants of a cysteine protease inhibitor derived from Trypanosoma brucei.	Acta crystallographica. Section F, Structural biology and crystallization communications 20060601
Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features.	The Biochemical journal 20060515
Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.	The Journal of antibiotics 20060501
Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family.	Journal of molecular biology 20060421
Stability of protease in organic solvent: structural identification by solid-state NMR of lyophilized papain before and after 1-propanol treatment and the corresponding enzymatic activities.	Biotechnology and bioengineering 20060405
Managing a traumatic wound in a geriatric patient.	Ostomy/wound management 20060401
Modulating the sensory response of a conjugated polymer by proteins: an agglutination assay for mercury ions in water.	Journal of the American Chemical Society 20060308
The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors.	The Journal of biological chemistry 20060303
Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI.	Biopolymers 20060301
Micronuclei evaluation of reduction in neoadjuvant chemotherapy related acute toxicity in locally advanced lung cancer: an indian experience.	The Journal of the Association of Physicians of India 20060301
Quantifying the protein core flexibility through analysis of cavity formation.	The Journal of chemical physics 20060221
Loosely packed papain prosegment displays inhibitory activity.	Archives of biochemistry and biophysics 20060215
Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG.	Structure (London, England : 1993) 20060201
Purification and characterization of extracellular cysteine protease inhibitor, ECPI-2, from Chlorella sp.	Journal of bioscience and bioengineering 20060201
[Impact on the model of rat osteoarthritis of jingu tablet].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201
Purification and characterization of novel proteinase inhibitors from dried figs.	Journal of agricultural and food chemistry 20060125
The effects of chemical and heat maceration techniques on the recovery of nuclear and mitochondrial DNA from bone.	Journal of forensic sciences 20060101
Antioxidant properties of enzymatic hydrolysates from royal jelly.	Journal of medicinal food 20060101
Deubiquitinating activity of the SARS-CoV papain-like protease.	Advances in experimental medicine and biology 20060101
Relative delivery efficiency and convenience of spray and ointment formulations of papain/urea/chlorophyllin enzymatic wound therapies.	Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20060101
Inhibition of mammalian cathepsins by Plesiomonas shigelloides.	Folia microbiologica 20060101
A reminder that ZZAP reagent removes complement in addition to IgG from coated RBCs.	Immunohematology 20060101
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.	The Journal of biological chemistry 20051202
Cystatins may confer viral resistance in plants by inhibition of a virus-induced cell death phenomenon in which cysteine proteinases are active: cloning and molecular characterization of a cDNA encoding cysteine-proteinase inhibitor (celostatin) from Celosia cristata (crested cock's comb).	Biotechnology and applied biochemistry 20051201
Isolation, characterization and kinetics of goat cystatins.	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20051201
Interaction of papain-like cysteine proteases with dipeptide-derived nitriles.	Journal of medicinal chemistry 20051201
Comparing two commercial enzymes to estimate in vitro proteolysis of purified or semi-purified proteins.	Journal of animal physiology and animal nutrition 20051201
Benzodioxole derivatives as negative effectors of plant proteases.	Journal of agricultural and food chemistry 20050921
A new multi-domain member of the cystatin superfamily expressed by Fasciola hepatica.	International journal for parasitology 20050901
[Oriented immobilization of papain on metal chelating carriers].	Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050901
Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition.	Biochemistry 20050802
Affinity selection to papain yields potent peptide inhibitors of cathepsins L, B, H, and K.	Biochemical and biophysical research communications 20050708
Light-induced inhibition of papain by a {Mn-NO}6 nitrosyl: identification of papain-SNO adduct by mass spectrometry.	Journal of inorganic biochemistry 20050701
Fluorogenic peptide substrates containing benzoxazol-5-yl-alanine derivatives for kinetic assay of cysteine proteases.	Analytical biochemistry 20050701
New non-peptidic inhibitors of papain derived from etacrynic acid.	Medicinal chemistry (Shariqah (United Arab Emirates)) 20050701
Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.	Bioorganic & medicinal chemistry letters 20050615
Papain entrapment in alginate beads for stability improvement and site-specific delivery: physicochemical characterization and factorial optimization using neural network modeling.	AAPS PharmSciTech 20050601
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.	Biochemistry 20050531
A serine proteinase inhibitor isolated from Tamarindus indica seeds and its effects on the release of human neutrophil elastase.	Life sciences 20050506
Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.	Chembiochem : a European journal of chemical biology 20050501
A novel cysteine protease inhibitor with lectin activity from the epidermis of the Japanese eel Anguilla japonica.	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050501
Pantothenic acid quantification: method comparison of a stable isotope dilution assay and a microbiological assay.	International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050501
Cysteines in CH1 underlie retention of unassembled Ig heavy chains.	The Journal of biological chemistry 20050415
Nitric oxide-related species-induced protein oxidation: reversible, irreversible, and protective effects on enzyme function of papain.	Free radical biology & medicine 20050415
Enzymic asymmetric hydrolysis of D,L-p-hydroxyphenylglycine methyl ester in aqueous ionic liquid co-solvent mixtures.	Biotechnology and applied biochemistry 20050401
1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase.	Archives of biochemistry and biophysics 20050401
Development and pharmacological characterization of a rat model of osteoarthritis pain.	Pain 20050401
Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast.	Journal of biochemistry 20050401
Conformational study of papain in the presence of sodium dodecyl sulfate in aqueous medium.	Colloids and surfaces. B, Biointerfaces 20050325
Identification of EhICP1, a chagasin-like cysteine protease inhibitor of Entamoeba histolytica.	FEBS letters 20050314
Purification and determination of inhibitory activity of recombinant soyacystatin for surimi application.	Molecular nutrition & food research 20050301
[The study on the treatment of Oviducts Ranae protein with enzyme hydrolysis].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301
Antioxidative ability in a linoleic acid oxidation system and scavenging abilities against active oxygen species of enzymatic hydrolysates from pollen Cistus ladaniferus.	International journal of molecular medicine 20050201
The biphasic response of porcine tendon to recombinant porcine growth hormone.	Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20050201
Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro.	Parasitology 20050201
Dissociation enzyme effects on the potassium currents of inner hair cells isolated from guinea-pig cochlea.	Hearing research 20050101
Exfoliation of Helicobacter pylori from gastric mucin by glycopolypeptides from buttermilk.	Journal of dairy science 20050101
2 devices that unclog feeding tubes.	RN 20050101
Antioxidant activity and angiotensin I-converting enzyme inhibition by enzymatic hydrolysates from bee bread.	Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101
Papain: a novel urine adulterant.	Journal of analytical toxicology 20050101
Papain gel: a new chemo-mechanical caries removal agent.	The Journal of clinical pediatric dentistry 20050101
Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH.	Archives of biochemistry and biophysics 20041201
Neural stem cell differentiation in a cell-collagen-bioreactor culture system.	Brain research. Developmental brain research 20041125
A multicystatin is induced by drought-stress in cowpea (Vigna unguiculata (L.) Walp.) leaves.	FEBS letters 20041119
Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.	Journal of molecular biology 20041105
The effects of Panafil when using topical negative pressure to heal an infected sternal wound.	Journal of wound care 20041101
Inhibitory effects of cystatins on proteolytic activities of the Plum pox potyvirus cysteine proteinases.	Virus research 20041001
Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor.	The journal of peptide research : official journal of the American Peptide Society 20041001
ECEPE proteins: a novel family of eukaryotic cysteine proteinases.	Trends in biochemical sciences 20041001
Foot-and-mouth disease virus leader proteinase: specificity at the P2 and P3 positions and comparison with other papain-like enzymes.	Biochemistry 20040914
Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward beta-sheet structure.	Biochemistry 20040907
Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase.	Plant physiology 20040901
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages.	The Journal of biological chemistry 20040827
BTLCP proteins: a novel family of bacterial transglutaminase-like cysteine proteinases.	Trends in biochemical sciences 20040801
Total enzymatic synthesis of cholecystokinin CCK-5.	Amino acids 20040801
Molecular cloning, expression, and functional characterization of a cystatin from pineapple stem.	Bioscience, biotechnology, and biochemistry 20040801
Drosophila long-term memory formation involves regulation of cathepsin activity.	Nature 20040722
Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.	Biochemistry 20040629
Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C.	The Journal of biological chemistry 20040604
Proteinases participating in the processing and activation of prolegumain in primary cultured rat macrophages.	Biological chemistry 20040601
Method for bacterial expression and purification of sesame cystatin via artificial oil bodies.	Journal of agricultural and food chemistry 20040519
A Kunitz-type inhibitor of coleopteran proteases, isolated from Adenanthera pavonina L. seeds and its effect on Callosobruchus maculatus.	Journal of agricultural and food chemistry 20040505
Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.	Biophysical journal 20040501
Kinetics of parasite cysteine proteinase inactivation by NO-donors.	Biochemical and biophysical research communications 20040312
Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.	The Biochemical journal 20040301
The N-terminus moiety of the cystatin SmCys from Schistosoma mansoni regulates its inhibitory activity in vitro and in vivo.	Molecular and biochemical parasitology 20040301
Debridement: controlling the necrotic/cellular burden.	Advances in skin & wound care 20040301
Sequential Development of Cysteine Proteinase Activities and Gene Expression during Somatic Embryogenesis in Carrot.	Bioscience, biotechnology, and biochemistry 20040301
[Immobilization and stabilization of papain on SiO2 particles containing amine groups].	Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040301
Structural basis of the unusual stability and substrate specificity of ervatamin C, a plant cysteine protease from Ervatamia coronaria.	Biochemistry 20040217
Regulation of collagenase activities of human cathepsins by glycosaminoglycans.	The Journal of biological chemistry 20040213
The ribbon of hydrogen bonds in globular proteins. IV. The example of the papain family.	Biopolymers 20040205
Production and activation of recombinant papain-like cysteine proteases.	Methods (San Diego, Calif.) 20040201
Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex.	The Plant journal : for cell and molecular biology 20040201
Thiirancarboxamides as inhibitors of papain.	Archiv der Pharmazie 20040201
Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability.	Biomaterials 20040101
Activity of immobilized papain dehydrated by n-propanol in low-water media.	Biotechnology letters 20040101
Molecular and biochemical assays of cartilage components.	Methods in molecular medicine 20040101
Insight into catalytic mechanism of papain-like cysteine proteinases: the case of D158.	Applied biochemistry and biotechnology 20040101
Characterization of free aromatic amino acids and estimation of exposition rate of phenylalanine in casein hydrolysates by second derivative spectrophotometry.	Acta cientifica venezolana 20040101
Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several cell types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs.	The Journal of general virology 20031201
Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.	The Journal of biological chemistry 20031128
Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.	The Journal of biological chemistry 20031114
Purification and properties of cysteine proteinase inhibitors from rabbit skeletal muscle.	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001
Grafting of features of cystatins C or B into the N-terminal region or second binding loop of cystatin A (stefin A) substantially enhances inhibition of cysteine proteinases.	Biochemistry 20030930
Applying the increase in rate constants of cooperative proteolysis to the determination of transition curves of protein denaturation.	Journal of biochemical and biophysical methods 20030930
Ca2+ binding to myosin regulatory light chain affects the conformation of the N-terminus of essential light chain and its binding to actin.	Archives of biochemistry and biophysics 20030915
Mechanisms and enzymes involved in SARS coronavirus genome expression.	The Journal of general virology 20030901
Electrostatic properties in the catalytic site of papain: A possible regulatory mechanism for the reactivity of the ion pair.	Proteins 20030801
Processing and subcellular localization of the leader papain-like proteinase of Beet yellows closterovirus.	The Journal of general virology 20030801
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.	Cell death and differentiation 20030801
Nontraditional wound care: A review of the evidence for the use of sugar, papaya/papain, and fatty acids.	Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20030701
Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems.	Biological chemistry 20030701
Variation in the pH-dependent pre-steady-state and steady-state kinetic characteristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion.	The Biochemical journal 20030615
Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment.	Journal of agricultural and food chemistry 20030604
AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death.	European journal of biochemistry 20030601
Enzymatic synthesis and characterization of l-methionine and 2-hydroxy-4-(methylthio)butanoic acid (HMB) co-oligomers.	Journal of agricultural and food chemistry 20030423
Enzymatic synthesis of a CCK-4 tripeptide fragment.	Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030401
Human eosinophils are activated by cysteine proteases and release inflammatory mediators.	The Journal of allergy and clinical immunology 20030401
Proteolytic enzyme conjugated to SC-glucan as an enzymatic transdermal drug penetration enhancer.	Die Pharmazie 20030401
Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS.	Biological chemistry 20030401
[X-ray microanalysis of the activity of immobilized papain].	Guang pu xue yu guang pu fen xi = Guang pu 20030401
The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2.	Endocrinology 20030301
N-terminal domain unfolds first in the sequential unfolding of papain.	Protein and peptide letters 20030201
Contributions of individual residues in the N-terminal region of cystatin B (stefin B) to inhibition of cysteine proteinases.	Biochimica et biophysica acta 20030131
Oriented versus random protein immobilization.	Journal of biochemical and biophysical methods 20030131
Frog saccular hair cells dissociated with protease VIII exhibit inactivating BK currents, K(V) currents, and low-frequency electrical resonance.	Hearing research 20030101
Morrenain b I, a papain-like endopeptidase from the latex of Morrenia brachystephana Griseb. (Asclepiadaceae).	Journal of protein chemistry 20030101
New cysteine protease inhibitors in physiological secretory fluids and their medical significance.	Advances in enzyme regulation 20030101
Properties of chemically oxidized kininogens.	Acta biochimica Polonica 20030101
Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets?	Biochemical Society symposium 20030101
[Interaction of human factor X with thromboplastin].	Biomeditsinskaia khimiia 20030101
Design and synthesis of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one derivatives as cysteine proteases inhibitors.	Bioorganic & medicinal chemistry letters 20021202
Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design.	Chemical reviews 20021201
Occurrence and structural characterization of versican-like proteoglycan in human vitreous.	Biochimie 20021201
[The preparation and identification of rabbit's antibody of chymopapain].	Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021201
Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.	The Biochemical journal 20021115
Overlapping binding sites for trypsin and papain on a Kunitz-type proteinase inhibitor from Prosopis juliflora.	Proteins 20021115
Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.	Journal of medicinal chemistry 20021107
Preparation and characterization of papain-modified sesame (Sesamum indicum L.) protein isolates.	Journal of agricultural and food chemistry 20021106
Protein engineering of nitrile hydratase activity of papain: molecular dynamics study of a mutant and wild-type enzyme.	Journal of the American Chemical Society 20021106
A randomized paired comparison trial of cutaneous treatments for acute jellyfish (Carybdea alata) stings.	The American journal of emergency medicine 20021101
Application potency of engineered G159 mutants on P1 substrate pocket of subtilisin YaB as improved meat tenderizers.	Journal of agricultural and food chemistry 20021009
Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design.	Chemistry & biology 20021001
Foot-and-mouth disease virus leader proteinase: a papain-like enzyme requiring an acidic environment in the active site.	FEBS letters 20020925
Enhancement of proteinase inhibitory activity of recombinant human cystatin C using random-centroid optimization.	Biochimica et biophysica acta 20020923
The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators.	Journal of molecular biology 20020920
A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.	The Biochemical journal 20020915
Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases.	Journal of medicinal chemistry 20020912
Cysteine proteinase inhibitors in elapid and hydrophiid snake venoms.	Toxicon : official journal of the International Society on Toxinology 20020901
The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells.	Biochemistry 20020820
Production, properties and specificity of a new bacterial L-fucose- and D-arabinose-binding lectin of the plant aggressive pathogen Ralstonia solanacearum, and its comparison to related plant and microbial lectins.	Journal of biochemistry 20020801
Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors.	Biochemistry 20020716
Enzymatic hydrolysis of nitriles by an engineered nitrile hydratase (papain Gln19Glu) in aqueous-organic media.	Biotechnology and bioengineering 20020705
Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.	Analytical and bioanalytical chemistry 20020701
Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the healthpoint system in the management of pressure ulcers.	Annals of plastic surgery 20020701
Calcium modulates protease resistance and carbohydrate binding of a plant defense legume lectin, Griffonia simplicifolia lectin II (GSII).	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601
Affinity of chicken cystatin for S-(carbamoylmethyl)-papain, measured by fluorescence at acidic pH.	Protein and peptide letters 20020601
Effect of urea at lower concentration on the structure of papain--formation of a stable molten globule and its characterization.	Indian journal of biochemistry & biophysics 20020601
The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.	The Biochemical journal 20020515
Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.	The Biochemical journal 20020501
Galactosaminoglycan composition in chicken eggshell.	Poultry science 20020501
A 40-kDa polypeptide from papain digestion of the rabbit intestinal Na+/phosphate cotransporter retains Na+ and phosphate cotransport.	Archives of biochemistry and biophysics 20020501
Red blood cells stimulate fibroblast-mediated contraction of three dimensional collagen gels in co-culture.	Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020501
Are PhAcOZ and Nsc suitable N alpha-protecting groups for protease-catalysed peptide synthesis?	Die Pharmazie 20020501
Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases.	Biochemistry 20020416
Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.	The Journal of biological chemistry 20020412
Conformational analysis of the GTP-binding protein MxA using limited proteolysis.	FEBS letters 20020410
Topology of the anion exchange protein AE1: the controversial sidedness of lysine 743.	Biochemistry 20020312
[Characterization of peptide and amino acid profile in casein hydrolysates].	Archivos latinoamericanos de nutricion 20020301
Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation.	The Journal of biological chemistry 20020222
Stabilization of molten globule state of papain by urea.	Biochemical and biophysical research communications 20020208
Cysteine protease gene expression and proteolytic activity during senescence of Alstroemeria petals.	Journal of experimental botany 20020201
Effect of metal ions on structure and activity of papain from Carica papaya.	Die Nahrung 20020201
A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage.	Analytical biochemistry 20020101
The Arabidopsis xylem peptidase XCP1 is a tracheary element vacuolar protein that may be a papain ortholog.	Plant physiology 20020101
Characterizing closely spaced, complex disulfide bond patterns in peptides and proteins by liquid chromatography/electrospray ionization tandem mass spectrometry.	Journal of mass spectrometry : JMS 20020101
Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester.	Biomacromolecules 20020101
Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.	Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101
The effects of the interaction of myosin essential light chain isoforms with actin in skeletal muscles.	Acta biochimica Polonica 20020101
Synthesis and biological properties of antitumor-active conjugates of ADR with dextran.	Journal of biomaterials science. Polymer edition 20020101
Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?	Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101
[Effect of shenmai injection and aminophylline on small airway smooth muscle cell apoptosis and related gene expression in rats with emphysema].	Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020101
Synthesis of cholecystokinin peptide CCK-4 exclusively by enzymatic methods.	Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101
[Characterization of cysteine proteinase endogenous inhibitors obtained from transformed fibroblasts].	Voprosy meditsinskoi khimii 20020101
[Reactions of derivatives of beta-lactam antibiotics with non-antibacterial biological activity].	Acta pharmaceutica Hungarica 20020101
Kinetics of modulation of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels by tetramethrin and deltamethrin.	The Journal of pharmacology and experimental therapeutics 20011201
Studies on the inactivation of soluble and immobilized papain by the ascorbic acid-Cu2+ system: a model to propose the effect of free radicals on membrane-bound enzymes in vivo.	Biotechnology and applied biochemistry 20011201
Identification, characterization and localization of chagasin, a tight-binding cysteine protease inhibitor in Trypanosoma cruzi.	Journal of cell science 20011101
Broad specificity alkaline proteases efficiently reduce the visual scaling associated with soap-induced xerosis.	Archives of dermatological research 20011101
Electrostatic recognition between enzyme and inhibitor: interaction between papain and leupeptin.	Archives of biochemistry and biophysics 20011015
Rapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cells.	The Journal of physiology 20011001
Domain-domain interactions of HtpG, an Escherichia coli homologue of eukaryotic HSP90 molecular chaperone.	European journal of biochemistry 20011001
The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs.	Biological chemistry 20011001
Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.	The Journal of biological chemistry 20010928
Proteinase activity in the white shrimp (Penaeus vannamei) clotting protein.	Biochemical and biophysical research communications 20010921
Vinyl sulfonium as novel proteolytic enzyme inhibitor.	Bioorganic & medicinal chemistry letters 20010903
Lysosomal cysteine proteases: facts and opportunities.	The EMBO journal 20010903
Interactions of human lacrimal and salivary cystatins with adenovirus endopeptidase.	Antiviral research 20010901
Role of the single cysteine residue, Cys 3, of human and bovine cystatin B (stefin B) in the inhibition of cysteine proteinases.	Protein science : a publication of the Protein Society 20010901
Channel cytoplasmic loops alter voltage-dependent sodium channel activation in an isoform-specific manner.	The Journal of physiology 20010901
Phage display selection of hairpin loop soyacystatin variants that mediate high affinity inhibition of a cysteine proteinase.	The Plant journal : for cell and molecular biology 20010901
The reaction of serpins with proteinases involves important enthalpy changes.	Biochemistry 20010821
Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases.	FEBS letters 20010803
Box jellyfish (Carybdea alata) in Waikiki. The analgesic effect of sting-aid, Adolph's meat tenderizer and fresh water on their stings: a double-blinded, randomized, placebo-controlled clinical trial.	Hawaii medical journal 20010801
Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.	The Biochemical journal 20010715
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.	Cancer chemotherapy and pharmacology 20010701
Retrolective cohort study of an additive therapy with an oral enzyme preparation in patients with multiple myeloma.	Cancer chemotherapy and pharmacology 20010701
Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.	The Journal of biological chemistry 20010601
Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.	Analytical biochemistry 20010601
Inhibition of cysteine protease activity by NO-donors.	Current protein & peptide science 20010601
Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors.	The Journal of biological chemistry 20010511
Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X.	Biochimica et biophysica acta 20010505
Counting the number of disulfides and thiol groups in proteins and a novel approach for determining the local pKa for cysteine groups in proteins in vivo.	Journal of synchrotron radiation 20010501
Fragmentation of immunoglobulin G.	Current protocols in immunology 20010501
The theory and application of transition state pK(a) values: the reaction of papain with a series of trimethylene disulphide reactivity probes.	Journal of theoretical biology 20010421
Insight into the catalysis of hydrolysis of four newly synthesized substrates by papain: a proton inventory study.	Biochemistry 20010403
Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism.	Cellular and molecular life sciences : CMLS 20010401
Molecular cloning and functional expression of cDNA encoding the cysteine proteinase inhibitor Sca from sunflower seeds.	Bioscience, biotechnology, and biochemistry 20010401
Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.	Current biology : CB 20010320
Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain family.	The Journal of biological chemistry 20010316
Paramyxovirus fusion (F) protein: a conformational change on cleavage activation.	Virology 20010301
S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.	European journal of biochemistry 20010301
A constitutive cystatin-encoding gene from barley (Icy) responds differentially to abiotic stimuli.	Plant molecular biology 20010301
A cystatin-based affinity procedure for the isolation and analysis of papain-like cysteine proteinases from tissue extracts.	Analytical biochemistry 20010215
Papain immobilization on a nitrilon fibre carrier containing primary amine groups.	Biotechnology and applied biochemistry 20010201
Interaction of cysteine proteases with calciotropic hormone receptors.	Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010201
Papain does not cleave operator-bound lambda repressor: structural characterization of the carboxy terminal domain and the hinge.	Journal of biomolecular structure & dynamics 20010201
Complex effects of papain on function and inhibitor sensitivity of the red cell anion exchanger AE1 suggest the presence of different transport subsites.	The Journal of membrane biology 20010201
High-level production of recombinant chicken cystatin by Pichia pastoris and its application in mackerel surimi.	Journal of agricultural and food chemistry 20010201
Identification of a membrane-associated cysteine protease with possible dual roles in the endoplasmic reticulum and protein storage vacuole.	The Journal of biological chemistry 20010105
Modification of cyclosporin A and conjugation of its derivative to HPMA copolymers.	Bioconjugate chemistry 20010101
Protons inhibit the BK(Ca) channel of rat small artery smooth muscle cells.	Journal of vascular research 20010101
[Anti-inflammatory activity of domestic papain].	Eksperimental'naia i klinicheskaia farmakologiia 20010101
The combined treatment of transplantable solid mammary carcinoma in Wistar rats by use of photodynamic therapy and cysteine proteinase inhibitor.	In vivo (Athens, Greece) 20010101
Immobilization of papain on cold-plasma functionalized polyethylene and glass surfaces.	Journal of biomaterials science. Polymer edition 20010101
Excitability in chemical and biochemical pH-autocatalytic systems.	Faraday discussions 20010101
Influence of organic solvents on papain kinetics.	Acta biochimica Polonica 20010101
Influence of Me2SO and incubation time on papain activity studied using fluorogenic substrates.	Acta biochimica Polonica 20010101
Synthesis of some pseudo-peptide analogs of thiol proteinase inhibitors.	Chemical & pharmaceutical bulletin 19990301
Chromogenic and fluorogenic glycosylated and acetylglycosylated peptides as substrates for serine, thiol and aspartyl proteases.	The journal of peptide research : official journal of the American Peptide Society 19990201
Domain structure and conformation of a cellobiohydrolase from Trichoderma pseudokiningii S-38.	Journal of protein chemistry 19970101
Amino acids and peptides. XXVIII. Preparation of poly(ethylene glycol) hybrids of Gln-Val-Val-Ala-Gly analogs and their inhibitory effect on papain.	Biological & pharmaceutical bulletin 19960601
Separation of functional domains for the alpha-1,4 and alpha-1,6 hydrolytic activities of a Bacillus amylopullulanase by limited proteolysis with papain.	Bioscience, biotechnology, and biochemistry 19960401
Interaction of ebselen with glutathione S-transferase and papain in vitro.	Biochemical pharmacology 19940315
Peptide production by a combination of gene expression, chemical synthesis, and protease-catalyzed conversion.	International journal of peptide and protein research 19930401
Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors.	Biochemistry 19921124
Papain-inhibitory activity of oryzacystatin, a rice seed cysteine proteinase inhibitor, depends on the central Gln-Val-Val-Ala-Gly region conserved among cystatin superfamily members.	Journal of biochemistry 19910201
An efficient chemical-enzymatic synthesis of LHRH N-terminal pentapeptide.	Biomedica biochimica acta 19910101
A methodological study of the enzymatic synthesis of the tripeptide Z-Cys(Bzl)-Tyr-Ile-OtBu.	Peptide research 19910101
The NH2-terminal 21 amino acid residues are not essential for the papain-inhibitory activity of oryzacystatin, a member of the cystatin superfamily. Expression of oryzacystatin cDNA and its truncated fragments in Escherichia coli.	The Journal of biological chemistry 19880605
Amino acids and peptides. XX. Inhibition of papain by succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide, a common sequence of endogenous thiol proteinase inhibitors.	Chemical & pharmaceutical bulletin 19880601
Significant effects of Z-Gln-Val-Val-OME, common sequences of thiol proteinase inhibitors on thiol proteinases.	Biochemical and biophysical research communications 19870313
Structural studies and two-dimensional gel electrophoresis of gamma-glutamyl transpeptidase.	Archives of biochemistry and biophysics 19860515
Carboxyl-modified amino acids and peptides as protease inhibitors.	Journal of medicinal chemistry 19860101
Significant effects of synthetic Gln-Val-Val-Ala-Gly and its derivatives, common sequences of thiol proteinase inhibitors, on thiol proteinase.	Chemical & pharmaceutical bulletin 19851101
Case report. Immunological studies in a case of hepatitis following methyldopa administration.	The American journal of the medical sciences 19790101
The pKa value of the active site histidine in photo-oxidised papain.	FEBS letters 19760101
The effect of acid treatment upon the susceptibility of rabbit IgG to proteolytic cleavage with various enzymes.	Immunochemistry 19750801

Fluorescence spectroscopic analysis of the interaction of papain with ionic liquids.

Applied biochemistry and biotechnology 20121001

Purification of chicken breast protein hydrolysate and analysis of its antioxidant activity.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001

Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121001

Cystatin B homolog from rock bream Oplegnathus fasciatus: genomic characterization, transcriptional profiling and protease-inhibitory activity of recombinant protein.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120901

Chondroprotective and anti-inflammatory effects of sesamin.

Phytochemistry 20120801

Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata.

Journal of agricultural and food chemistry 20120801

Purification and identification of antioxidant peptides from egg white protein hydrolysate.

Amino acids 20120701

Cryptostatin, a chagasin-family cysteine protease inhibitor of Cryptosporidium parvum.

Parasitology 20120701

Papain-specific activating esters in aqueous dipeptide synthesis.

Chembiochem : a European journal of chemical biology 20120618

Optimisation of hydrolysis of purple sea urchin (Strongylocentrotus nudus) gonad by response surface methodology and evaluation of in vitro antioxidant activity of the hydrolysate.

Journal of the science of food and agriculture 20120601

Influence of incubation conditions on hydrolysis efficiency and iodine enrichment in baker's yeast.

Biological trace element research 20120601

Purification of papain using reactive green 5 attached supermacroporous monolithic cryogel.

Applied biochemistry and biotechnology 20120601

Reactivity of nitroxyl-derived sulfinamides.

Biochemistry 20120522

Optimization of a microwave-coupled enzymatic digestion process to prepare peanut peptides.

Molecules (Basel, Switzerland) 20120511

C1A cysteine-proteases and their inhibitors in plants.

Physiologia plantarum 20120501

Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity.

The Journal of allergy and clinical immunology 20120501

Aggregation and inactivation of pancreatic cystatin by riboflavin-derived singlet oxygen and flavin triplet state: polyphenols as preventive agents.

Journal of biochemical and molecular toxicology 20120501

A dityrosine-based substrate for a protease assay: application for the selective assessment of papain and chymopapain activity.

Analytica chimica acta 20120420

Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

Plant physiology 20120401

3-aminopiperidine-based peptide analogues as the first selective noncovalent inhibitors of the bacterial cysteine protease IdeS.

Journal of medicinal chemistry 20120322

A potent, versatile disulfide-reducing agent from aspartic acid.

Journal of the American Chemical Society 20120307

Enzyme catalytic promiscuity: The papain-catalyzed Knoevenagel reaction.

Biochimie 20120301

Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets.

Journal of medicinal food 20120301

Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody.

Pharmaceutical research 20120101

Assessment of the angiotensin-I-converting enzyme (ACE-I) inhibitory and antioxidant activities of hydrolysates of bovine brisket sarcoplasmic proteins produced by papain and characterisation of associated bioactive peptidic fractions.

Meat science 20120101

Rodent retinal ganglion cell cultures.

Methods in molecular biology (Clifton, N.J.) 20120101

Clinical evaluation of caries removal in primary teeth using conventional, chemomechanical and laser technique: an in vivo study.

The journal of contemporary dental practice 20120101

Production of defatted palm kernel cake protein hydrolysate as a valuable source of natural antioxidants.

International journal of molecular sciences 20120101

Isolation and gene expression analysis of a papain-type cysteine protease in thermogenic skunk cabbage (Symplocarpus renifolius).

Bioscience, biotechnology, and biochemistry 20120101

The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.

Archives of biochemistry and biophysics 20111215

Identification of interactions involved in the generation of nucleophilic reactivity and of catalytic competence in the catalytic site Cys/His ion pair of papain.

Biochemistry 20111213

Free radical scavenging and angiotensin-I converting enzyme inhibitory peptides from Pacific cod (Gadus macrocephalus) skin gelatin.

International journal of biological macromolecules 20111201

Interactions of nanobubbles with bovine serum albumin and papain films on gold surfaces.

Biointerphases 20111201

Efficacy of chitooligosaccharides for the management of diabetes in alloxan induced mice: a correlative study with antihyperlipidemic and antioxidative activity.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Development of a new experimental model of saccular aneurysm by intra-arterial incubation of papain in rabbits.

Neuroradiology 20111101

3A4, a new potential target for B and myeloid lineage leukemias.

Journal of drug targeting 20111101

Immobilization and stabilization of papain on poly(hydroxyethyl methacrylate-ethylenglycol dimethacrylate) beads grafted with epoxy functional polymer chains via surface-initiated-atom transfer radical polymerization (SI-ATRP).

Bioresource technology 20111101

Metal ion mediated self-assembly directed formation of protein arrays.

Biomacromolecules 20111010

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.

Nature immunology 20111009

Respiratory mechanics do not always mirror pulmonary histological changes in emphysema.

Clinics (Sao Paulo, Brazil) 20111001

Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.

Chembiochem : a European journal of chemical biology 20110919

Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration.

Organic & biomolecular chemistry 20110821

Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts--an in vitro study.

International journal of dental hygiene 20110801

Crystal structure of tarocystatin-papain complex: implications for the inhibition property of group-2 phytocystatins.

Planta 20110801

Keratin film made of human hair as a nail plate model for studying drug permeation.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801

Antioxidant and antiproliferative activities of loach ( Misgurnus anguillicaudatus ) peptides prepared by papain digestion.

Journal of agricultural and food chemistry 20110727

Isolation and characterization of three novel peptides from casein hydrolysates that stimulate the growth of mixed cultures of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus.

Journal of agricultural and food chemistry 20110713

Ribosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies.

Molecular biotechnology 20110701

The nonstructural protein 1 papain-like cysteine protease was necessary for porcine reproductive and respiratory syndrome virus nonstructural protein 1 to inhibit interferon-β induction.

DNA and cell biology 20110601

Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events.

Journal of immunology (Baltimore, Md. : 1950) 20110601

A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.

Journal of microbiology and biotechnology 20110601

Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity.

Biochemical and biophysical research communications 20110513

The mechanism of papain inhibition by peptidyl aldehydes.

Proteins 20110301

Molecular cloning and biochemical characterization of a novel cystatin from Hevea rubber latex.

Plant physiology and biochemistry : PPB 20110301

Metastability of papain and the molecular mechanism for its sequential acid-denaturation.

The protein journal 20110301

Morphology and microtensile bond strength of adhesive systems to in situ-formed caries-affected dentin after the use of a papain-based chemomechanical gel method.

American journal of dentistry 20110201

Backbone degradable multiblock N-(2-hydroxypropyl)methacrylamide copolymer conjugates via reversible addition-fragmentation chain transfer polymerization and thiol-ene coupling reaction.

Biomacromolecules 20110110

Surface Plasmon Resonance Imaging (SPRI) sensor for cystatin determination based on immobilized papain.

Protein and peptide letters 20110101

PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway.

PloS one 20110101

Sodium tetrathionate effect on papain purification from different Carica papaya latex crude extracts.

Preparative biochemistry & biotechnology 20110101

Papain-like proteases of Staphylococcus aureus.

Advances in experimental medicine and biology 20110101

Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.

PloS one 20110101

Development of enteric submicron particle formulation of papain for oral delivery.

International journal of nanomedicine 20110101

Kinetically controlled enzymatic synthesis of dipeptide precursor of L-alanyl-L-glutamine.

Biotechnology and applied biochemistry 20110101

An evaluation of different caries removal techniques in primary teeth: a comparitive clinical study.

The Journal of clinical pediatric dentistry 20110101

Removal of mercury (II) from aqueous solution using papain immobilized on alginate bead: optimization of immobilization condition and modeling of removal study.

Bioresource technology 20101201

Reduction of benzaldehyde catalyzed by papain-based semisynthetic enzymes.

Applied biochemistry and biotechnology 20101101

High level production of bioactive di- and tri-tyrosine peptides by protease-catalyzed reactions.

Journal of biotechnology 20101101

The effect of various wound dressings on the activity of debriding enzymes.

Advances in skin & wound care 20101001

A distinct subfamily of papain-like cystein proteinases regulated by senescence and stresses in Glycine max.

Journal of plant physiology 20100901

Plant cysteine proteases that evoke itch activate protease-activated receptors.

The British journal of dermatology 20100901

Identification and characterization of a Cystatin gene from Chinese mitten crab Eriocheir sinensis.

Fish & shellfish immunology 20100901

Structural and mechanistic insights into a novel non-competitive Kunitz trypsin inhibitor from Adenanthera pavonina L. seeds with double activity toward serine- and cysteine-proteinases.

Journal of molecular graphics & modelling 20100901

Optimization of hydrolysis conditions for the production of antioxidant peptides from fish gelatin using response surface methodology.

Journal of food science 20100801

Isolation, structure, and functional elucidation of a modified pentapeptide, cysteine protease inhibitor (CPI-2081) from Streptomyces species 2081 that exhibit inhibitory effect on cancer cell migration.

Journal of medicinal chemistry 20100722

The effects of different maceration techniques on nuclear DNA amplification using human bone.

Journal of forensic sciences 20100701

The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

Nature immunology 20100701

Mesoporous organosilicas with ultra-large pores: mesophase transformation and bioadsorption properties.

Journal of colloid and interface science 20100601

Improving thermostability of papain through structure-based protein engineering.

Protein engineering, design & selection : PEDS 20100601

Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway.

Journal of Korean medical science 20100601

Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules.

European journal of medicinal chemistry 20100501

A study of the efficacy of cleansers for acne vulgaris.

The Journal of dermatological treatment 20100501

Effect of neutrase, alcalase, and papain hydrolysis of whey protein concentrates on iron uptake by Caco-2 cells.

Journal of agricultural and food chemistry 20100428

Effects of a novel pathogenesis-related class 10 (PR-10) protein from Crotalaria pallida Roots with papain inhibitory activity against root-knot nematode Meloidogyne incognita.

Journal of agricultural and food chemistry 20100414

Behavior of papain in mixed micelles of anionic-cationic surfactants having similar tails and dissimilar head groups.

Journal of colloid and interface science 20100401

Crystal structure of human cystatin C stabilized against amyloid formation.

The FEBS journal 20100401

Even-numbered peptides from a papain hydrolysate of silk fibroin.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315

Cysteine enhances activity and stability of immobilized papain.

Amino acids 20100301

In silico analysis of sequential, structural and functional diversity of wheat cystatins and its implication in plant defense.

Genomics, proteomics & bioinformatics 20100301

[Enzymatic production of oral nutritional liquid from oyster].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100301

Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule.

Analytical biochemistry 20100201

[Fluorescence spectra analysis of papain structure treated by dynamic high pressure microfluidization in low pressure ranges].

Guang pu xue yu guang pu fen xi = Guang pu 20100201

Method for studying immunoglobulin G binding on hydrophobic surfaces.

Langmuir : the ACS journal of surfaces and colloids 20100119

Immobilization of modified papain with anhydride groups on activated cotton fabric.

Applied biochemistry and biotechnology 20100101

The importance of correct protein concentration for kinetics and affinity determination in structure-function analysis.

Journal of visualized experiments : JoVE 20100101

Purification and in situ immobilization of papain with aqueous two-phase system.

PloS one 20100101

[The use of enzymatic hydrolysis for isolation of barbituric acid derivatives from blood (as exemplified by phenobarbital and barbamyl)].

Sudebno-meditsinskaia ekspertiza 20100101

Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain.

Proteins 20091201

A salivary cystatin, HlSC-1, from the ixodid tick Haemaphysalis longicornis play roles in the blood-feeding processes.

Parasitology research 20091201

Dipeptide-derived nitriles containing additional electrophilic sites: potentially irreversible inhibitors of cysteine proteases.

Journal of enzyme inhibition and medicinal chemistry 20091201

Two routes for production and purification of Fab fragments in biopharmaceutical discovery research: Papain digestion of mAb and transient expression in mammalian cells.

Protein expression and purification 20091001

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.

Journal of pharmaceutical sciences 20091001

Profiling of calpain activity with a series of FRET-based substrates.

Biochimica et biophysica acta 20091001

Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats.

Arthritis and rheumatism 20091001

Sensory crispness of crispy rolls: effect of formulation, storage conditions, and water distribution in the crust.

Journal of food science 20091001

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.

Analytical biochemistry 20090915

Effects of sodium ferulate on human osteoarthritic chondrocytes and osteoarthritis in rats.

Clinical and experimental pharmacology & physiology 20090901

Proteomic identification of an MHC-binding peptidome from pancreas and breast cancer cell lines.

Molecular immunology 20090901

Hydrolytic properties and substrate specificity of the foot-and-mouth disease leader protease.

Biochemistry 20090825

Polyrotaxane composed of poly-L-lactide and alpha-cyclodextrin exhibiting protease-triggered hydrolysis.

Biomacromolecules 20090810

Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.

The Journal of organic chemistry 20090807

eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain.

Journal of inorganic biochemistry 20090801

Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera.

The FEBS journal 20090801

Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2.

Journal of immunology (Baltimore, Md. : 1950) 20090715

Sulfonation of papain-treated chitosan and its mechanism for anticoagulant activity.

Carbohydrate research 20090706

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response.

Nature immunology 20090701

Antithrombotic papain-hydrolyzed peptides isolated from pork meat.

Thrombosis research 20090301

Production and recovery of recombinant propapain with high yield.

Phytochemistry 20090301

Evaluation of alpha,beta-unsaturated ketone-based probes for papain-family cysteine proteases.

Bioorganic & medicinal chemistry 20090201

Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases.

The FEBS journal 20090201

Close proximity of myosin loop 3 to troponin determined by triangulation of resonance energy transfer distance measurements.

Biochemistry 20090120

Enantioselective reductive amination of alpha-keto acids by papain-based semisynthetic enzyme.

Biochemistry. Biokhimiia 20090101

Biocompatibility analysis of chemomechanical caries removal material Papacárie on cultured fibroblasts and subcutaneous tissue.

Journal of dentistry for children (Chicago, Ill.) 20090101

Two Kunitz-type inhibitors with activity against trypsin and papain from Pithecellobium dumosum seeds: purification, characterization, and activity towards pest insect digestive enzyme.

Protein and peptide letters 20090101

Biochemical and PMF MALDI-TOF analyses of two novel papain-like plant proteinases.

Protein and peptide letters 20090101

Antioxidant activities of hydrolysates of Arca subcrenata prepared with three proteases.

Marine drugs 20081201

Development of immunoaffinity restricted access media for rapid extractions of low-mass analytes.

Analytical chemistry 20081115

Identifying and characterizing the biological targets of metallotherapeutics: Two approaches using Au(I)-protein interactions as model systems.

Analytical biochemistry 20081101

Hormone induced changes in lactase glycosylation in developing rat intestine.

Molecular and cellular biochemistry 20081101

A pulse--radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity.

Free radical biology & medicine 20081101

[Gastric bezoar as complication of gastric banding. Report of one case].

Revista medica de Chile 20081101

Characterization of inhibitory mechanism and antifungal activity between group-1 and group-2 phytocystatins from taro (Colocasia esculenta).

The FEBS journal 20081001

Peptidyl epoxides extended in the P' direction as cysteine protease inhibitors: effect on affinity and mechanism of inhibition.

Bioorganic & medicinal chemistry 20081001

[The enzyme papain in industry and food causes allergic sensitization].

Ugeskrift for laeger 20080929

Two cysteine proteinase inhibitors from Arabidopsis thaliana, AtCYSa and AtCYSb, increasing the salt, drought, oxidation and cold tolerance.

Plant molecular biology 20080901

Plant cysteine proteinases: evaluation of the pharmacological activity.

Phytochemistry 20080901

Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.

Nature chemical biology 20080901

Internalization of cystatin C in human cell lines.

The FEBS journal 20080901

Fluorescence of primary dentine after chemomechanical and conventional rotary excavation.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 20080901

Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.

The Journal of biological chemistry 20080815

Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L.

Molecular pharmacology 20080701

Hybrid protease inhibitors for pest and pathogen control--a functional cost for the fusion partners?

Plant physiology and biochemistry : PPB 20080701

Molecular docking of cathepsin L inhibitors in the binding site of papain.

Journal of chemical information and modeling 20080701

[Prokaryotic expression of OC-IdeltaD86 (Oryzacystatin-IdeltaD86) gene and analysis of its activity].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080701

Characterization of a three-component coupling reaction on proteins by isotopic labeling and nuclear magnetic resonance spectroscopy.

Journal of the American Chemical Society 20080618

Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype.

Bioorganic & medicinal chemistry letters 20080615

Isolation and characterization of a cDNA encoding a papain-like cysteine protease from alfalfa.

DNA sequence : the journal of DNA sequencing and mapping 20080601

Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.

Biochimica et biophysica acta 20080601

Mechanism for stabilization of the molten globule state of papain by sodium n-alkyl sulfates: spectroscopic and calorimetric approaches.

Journal of colloid and interface science 20080601

Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion.

Analytical chemistry 20080601

A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture.

Virology 20080510

Stabilization of scleral collagen by glycerol aldehyde cross-linking.

Biochimica et biophysica acta 20080501

Glycosylation profiling of a therapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer.

Analytical biochemistry 20080415

Free radical scavenging activity of a novel antioxidative peptide purified from hydrolysate of bullfrog skin, Rana catesbeiana Shaw.

Bioresource technology 20080401

Separation and characterization of the colored material from sugarcane molasses.

Chemosphere 20080401

Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.

Biochemistry 20080219

Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria.

The FEBS journal 20080201

The nsp1alpha and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis.

The Journal of general virology 20080201

Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae.

Microbiological research 20080101

2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation.

Molecular cancer therapeutics 20080101

Plant proteases: from phenotypes to molecular mechanisms.

Annual review of plant biology 20080101

Bovine explant model of degeneration of the intervertebral disc.

BMC musculoskeletal disorders 20080101

Evaluation of residual dentin after conventional and chemomechanical caries removal using SEM.

The Journal of clinical pediatric dentistry 20080101

Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.

Angewandte Chemie (International ed. in English) 20080101

Enzymatic wound debridement.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20080101

Strategies for addressing restorative challenges in HIV-infected children.

Journal of dentistry for children (Chicago, Ill.) 20080101

Chemo-mechanical removal of caries in an adolescent patient using a papain gel: case report.

The Journal of clinical pediatric dentistry 20080101

Papain adulteration in 11-nor-Delta9-tetrahydrocannabinol- 9-carboxylic acid-positive urine samples.

Journal of analytical toxicology 20080101

[Chemoenzymatic synthesis of new fluorogenous substrates for cysteine proteases of the papain family].

Bioorganicheskaia khimiia 20080101

Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders.

Molecular plant pathology 20080101

[Isolation of blood caffeine as a model substance by enzymatic hydrolysis].

Sudebno-meditsinskaia ekspertiza 20080101

Albumin competitively inhibits glycation of less abundant proteins.

Protein and peptide letters 20080101

[Study of therapeutic effect and mechanism of Sihuang powder treating acute synovitis in experimental rabbit induced by papain injection].

Zhongguo gu shang = China journal of orthopaedics and traumatology 20080101

Inhibition of ice crystal growth in ice cream mix by gelatin hydrolysate.

Journal of agricultural and food chemistry 20071226

GrpE N-terminal domain contributes to the interaction with Dnak and modulates the dynamics of the chaperone substrate binding domain.

Journal of molecular biology 20071207

[Fluorescence spectra analysis of papain treated by pulsed electric field].

Guang pu xue yu guang pu fen xi = Guang pu 20071201

Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.

Bioorganic & medicinal chemistry 20071115

Mechanism of solvent induced thermal stabilization of papain.

International journal of biological macromolecules 20071001

Physicochemical and bitterness properties of enzymatic pea protein hydrolysates.

Journal of food science 20071001

Pore-size tunable mesoporous zirconium organophosphonates with chiral L-proline for enzyme adsorption.

Inorganic chemistry 20070917

Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.

Journal of chromatography. A 20070914

Preparation of hydrophilic polyhydroxyalkyl glutamine crosslinked films and its biodegradability.

Journal of biomaterials applications 20070901

Purification of a cysteine protease inhibitor from larval hemolymph of the tobacco hornworm (Manduca sexta) and functional expression of the recombinant protein.

Insect biochemistry and molecular biology 20070901

Enzymatic hydrolysis of heated whey: iron-binding ability of peptides and antigenic protein fractions.

Journal of dairy science 20070901

Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.

Neoplasia (New York, N.Y.) 20070901

Domain organization and movements in heavy metal ion pumps: papain digestion of CopA, a Cu+-transporting ATPase.

The Journal of biological chemistry 20070831

The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.

Bioorganic & medicinal chemistry 20070801

The catalytic mode of cysteine proteinases of papain (C1) family.

Bioresource technology 20070701

Cloning and characterisation of the Anisakis simplex allergen Ani s 4 as a cysteine-protease inhibitor.

International journal for parasitology 20070701

Effect of polyethylene glycols on the function and structure of thiol proteases.

Journal of biochemistry 20070701

Carboxy terminal extended phytocystatins are bifunctional inhibitors of papain and legumain cysteine proteinases.

FEBS letters 20070626

Application of recombinant chum salmon cystatin to Alaska pollock (Theragra chalcogramma) surimi to prevent gel weakening.

Journal of food science 20070601

Multiple domains of endopin 2A for serpin cross-class inhibition of papain.

Archives of biochemistry and biophysics 20070515

Effects of knee injection on skeletal muscle metabolism and contractile force in rats.

Osteoarthritis and cartilage 20070501

Structure of the mexicain-E-64 complex and comparison with other cysteine proteases of the papain family.

Acta crystallographica. Section D, Biological crystallography 20070501

Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.

Chemistry & biology 20070501

[Resonance scattering spectral assay of papain enzymatic activity with sodium dodecyl benzene sulfonate].

Guang pu xue yu guang pu fen xi = Guang pu 20070501

Active fragments of the antihemorrhagic protein HSF from serum of habu (Trimeresurus flavoviridis).

Toxicon : official journal of the International Society on Toxinology 20070401

Bicyclic carbamates as inhibitors of papain-like cathepsin proteases.

Bioorganic & medicinal chemistry letters 20070301

Effect of both ultraviolet B irradiation and histamine receptor function on allergic responses to an inhaled antigen.

Journal of immunology (Baltimore, Md. : 1950) 20070301

Characterization of hydrolysates derived from enzymatic hydrolysis of wheat gluten.

Journal of food science 20070301

Cysteine-specific, covalent anchoring of transition organometallic complexes to the protein papain from Carica papaya.

Chembiochem : a European journal of chemical biology 20070122

Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo.

Parasitology 20070101

Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.

Molecular and biochemical parasitology 20070101

A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease.

Plant physiology 20070101

A silicone-based controlled-release device for accelerated proteolytic debridement of wounds.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101

Heterogeneity of proteinase inhibitors in the water-soluble organic matrix from the oyster nacre.

Marine biotechnology (New York, N.Y.) 20070101

Aerosol probes of emphysema progression in dogs treated with all trans retinoic acid--an exploratory study.

Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20070101

Chemical versus conventional caries removal techniques in primary teeth: a microhardness study.

The Journal of clinical pediatric dentistry 20070101

Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles.

Bioconjugate chemistry 20070101

Fc glycans terminated with N-acetylglucosamine residues increase antibody resistance to papain.

Biotechnology progress 20070101

The Surface Plasmon Resonance Imaging sensor for papain based on immobilized cystatin.

Protein and peptide letters 20070101

Purification and characterization of a trypsin-papain inhibitor from Pithecelobium dumosum seeds and its in vitro effects towards digestive enzymes from insect pests.

Plant physiology and biochemistry : PPB 20070101

Influence of papain urea copper chlorophyllin on wound matrix remodeling.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101

[Ubiquitin causes selective increase in the sensitivity of rat brain mitochondrial monoamine oxidases to various proteases].

Biomeditsinskaia khimiia 20070101

In vitro study of the effectiveness of different dressings for debriding fibrin in blood clots from horses.

The Veterinary record 20061118

Kosmotropic salt activation and substrate specificity of poliovirus protease 3C.

Biochemistry 20061003

Meat tenderizing effect of injecting encapsulated Ca2+ in liposome into rabbit before slaughter.

Bioscience, biotechnology, and biochemistry 20061001

Characterization of partially folded intermediates of papain in presence of cationic, anionic, and nonionic detergents at low pH.

Biopolymers 20060901

Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols.

The Biochemical journal 20060901

Molecular cloning, sequencing, expression of Chinese sturgeon cystatin in yeast Pichia pastoris and its proteinase inhibitory activity.

Journal of biotechnology 20060901

Antioxidant activity of zein hydrolysates in a liposome system and the possible mode of action.

Journal of agricultural and food chemistry 20060809

Dipeptide vinyl sultams: synthesis via the Wittig-Horner reaction and activity against papain, falcipain-2 and Plasmodium falciparum.

Bioorganic & medicinal chemistry letters 20060801

Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.

Plant physiology 20060701

Recombinant expression, purification, and functional analysis of two novel cystatins from sugarcane (Saccharum officinarum).

Protein expression and purification 20060601

Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.

Chembiochem : a European journal of chemical biology 20060601

High-resolution complex of papain with remnants of a cysteine protease inhibitor derived from Trypanosoma brucei.

Acta crystallographica. Section F, Structural biology and crystallization communications 20060601

Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features.

The Biochemical journal 20060515

Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.

The Journal of antibiotics 20060501

Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family.

Journal of molecular biology 20060421

Stability of protease in organic solvent: structural identification by solid-state NMR of lyophilized papain before and after 1-propanol treatment and the corresponding enzymatic activities.

Biotechnology and bioengineering 20060405

Managing a traumatic wound in a geriatric patient.

Ostomy/wound management 20060401

Modulating the sensory response of a conjugated polymer by proteins: an agglutination assay for mercury ions in water.

Journal of the American Chemical Society 20060308

The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors.

The Journal of biological chemistry 20060303

Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI.

Biopolymers 20060301

Micronuclei evaluation of reduction in neoadjuvant chemotherapy related acute toxicity in locally advanced lung cancer: an indian experience.

The Journal of the Association of Physicians of India 20060301

Quantifying the protein core flexibility through analysis of cavity formation.

The Journal of chemical physics 20060221

Loosely packed papain prosegment displays inhibitory activity.

Archives of biochemistry and biophysics 20060215

Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG.

Structure (London, England : 1993) 20060201

Purification and characterization of extracellular cysteine protease inhibitor, ECPI-2, from Chlorella sp.

Journal of bioscience and bioengineering 20060201

[Impact on the model of rat osteoarthritis of jingu tablet].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

Purification and characterization of novel proteinase inhibitors from dried figs.

Journal of agricultural and food chemistry 20060125

The effects of chemical and heat maceration techniques on the recovery of nuclear and mitochondrial DNA from bone.

Journal of forensic sciences 20060101

Antioxidant properties of enzymatic hydrolysates from royal jelly.

Journal of medicinal food 20060101

Deubiquitinating activity of the SARS-CoV papain-like protease.

Advances in experimental medicine and biology 20060101

Relative delivery efficiency and convenience of spray and ointment formulations of papain/urea/chlorophyllin enzymatic wound therapies.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20060101

Inhibition of mammalian cathepsins by Plesiomonas shigelloides.

Folia microbiologica 20060101

A reminder that ZZAP reagent removes complement in addition to IgG from coated RBCs.

Immunohematology 20060101

Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.

The Journal of biological chemistry 20051202

Cystatins may confer viral resistance in plants by inhibition of a virus-induced cell death phenomenon in which cysteine proteinases are active: cloning and molecular characterization of a cDNA encoding cysteine-proteinase inhibitor (celostatin) from Celosia cristata (crested cock's comb).

Biotechnology and applied biochemistry 20051201

Isolation, characterization and kinetics of goat cystatins.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20051201

Interaction of papain-like cysteine proteases with dipeptide-derived nitriles.

Journal of medicinal chemistry 20051201

Comparing two commercial enzymes to estimate in vitro proteolysis of purified or semi-purified proteins.

Journal of animal physiology and animal nutrition 20051201

Benzodioxole derivatives as negative effectors of plant proteases.

Journal of agricultural and food chemistry 20050921

A new multi-domain member of the cystatin superfamily expressed by Fasciola hepatica.

International journal for parasitology 20050901

[Oriented immobilization of papain on metal chelating carriers].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050901

Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition.

Biochemistry 20050802

Affinity selection to papain yields potent peptide inhibitors of cathepsins L, B, H, and K.

Biochemical and biophysical research communications 20050708

Light-induced inhibition of papain by a {Mn-NO}6 nitrosyl: identification of papain-SNO adduct by mass spectrometry.

Journal of inorganic biochemistry 20050701

Fluorogenic peptide substrates containing benzoxazol-5-yl-alanine derivatives for kinetic assay of cysteine proteases.

Analytical biochemistry 20050701

New non-peptidic inhibitors of papain derived from etacrynic acid.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20050701

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.

Bioorganic & medicinal chemistry letters 20050615

Papain entrapment in alginate beads for stability improvement and site-specific delivery: physicochemical characterization and factorial optimization using neural network modeling.

AAPS PharmSciTech 20050601

The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.

Biochemistry 20050531

A serine proteinase inhibitor isolated from Tamarindus indica seeds and its effects on the release of human neutrophil elastase.

Life sciences 20050506

Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.

Chembiochem : a European journal of chemical biology 20050501

A novel cysteine protease inhibitor with lectin activity from the epidermis of the Japanese eel Anguilla japonica.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050501

Pantothenic acid quantification: method comparison of a stable isotope dilution assay and a microbiological assay.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050501

Cysteines in CH1 underlie retention of unassembled Ig heavy chains.

The Journal of biological chemistry 20050415

Nitric oxide-related species-induced protein oxidation: reversible, irreversible, and protective effects on enzyme function of papain.

Free radical biology & medicine 20050415

Enzymic asymmetric hydrolysis of D,L-p-hydroxyphenylglycine methyl ester in aqueous ionic liquid co-solvent mixtures.

Biotechnology and applied biochemistry 20050401

1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase.

Archives of biochemistry and biophysics 20050401

Development and pharmacological characterization of a rat model of osteoarthritis pain.

Pain 20050401

Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast.

Journal of biochemistry 20050401

Conformational study of papain in the presence of sodium dodecyl sulfate in aqueous medium.

Colloids and surfaces. B, Biointerfaces 20050325

Identification of EhICP1, a chagasin-like cysteine protease inhibitor of Entamoeba histolytica.

FEBS letters 20050314

Purification and determination of inhibitory activity of recombinant soyacystatin for surimi application.

Molecular nutrition & food research 20050301

[The study on the treatment of Oviducts Ranae protein with enzyme hydrolysis].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Antioxidative ability in a linoleic acid oxidation system and scavenging abilities against active oxygen species of enzymatic hydrolysates from pollen Cistus ladaniferus.

International journal of molecular medicine 20050201

The biphasic response of porcine tendon to recombinant porcine growth hormone.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20050201

Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro.

Parasitology 20050201

Dissociation enzyme effects on the potassium currents of inner hair cells isolated from guinea-pig cochlea.

Hearing research 20050101

Exfoliation of Helicobacter pylori from gastric mucin by glycopolypeptides from buttermilk.

Journal of dairy science 20050101

2 devices that unclog feeding tubes.

RN 20050101

Antioxidant activity and angiotensin I-converting enzyme inhibition by enzymatic hydrolysates from bee bread.

Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Papain: a novel urine adulterant.

Journal of analytical toxicology 20050101

Papain gel: a new chemo-mechanical caries removal agent.

The Journal of clinical pediatric dentistry 20050101

Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH.

Archives of biochemistry and biophysics 20041201

Neural stem cell differentiation in a cell-collagen-bioreactor culture system.

Brain research. Developmental brain research 20041125

A multicystatin is induced by drought-stress in cowpea (Vigna unguiculata (L.) Walp.) leaves.

FEBS letters 20041119

Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.

Journal of molecular biology 20041105

The effects of Panafil when using topical negative pressure to heal an infected sternal wound.

Journal of wound care 20041101

Inhibitory effects of cystatins on proteolytic activities of the Plum pox potyvirus cysteine proteinases.

Virus research 20041001

Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor.

The journal of peptide research : official journal of the American Peptide Society 20041001

ECEPE proteins: a novel family of eukaryotic cysteine proteinases.

Trends in biochemical sciences 20041001

Foot-and-mouth disease virus leader proteinase: specificity at the P2 and P3 positions and comparison with other papain-like enzymes.

Biochemistry 20040914

Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward beta-sheet structure.

Biochemistry 20040907

Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase.

Plant physiology 20040901

Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages.

The Journal of biological chemistry 20040827

BTLCP proteins: a novel family of bacterial transglutaminase-like cysteine proteinases.

Trends in biochemical sciences 20040801

Total enzymatic synthesis of cholecystokinin CCK-5.

Amino acids 20040801

Molecular cloning, expression, and functional characterization of a cystatin from pineapple stem.

Bioscience, biotechnology, and biochemistry 20040801

Drosophila long-term memory formation involves regulation of cathepsin activity.

Nature 20040722

Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.

Biochemistry 20040629

Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C.

The Journal of biological chemistry 20040604

Proteinases participating in the processing and activation of prolegumain in primary cultured rat macrophages.

Biological chemistry 20040601

Method for bacterial expression and purification of sesame cystatin via artificial oil bodies.

Journal of agricultural and food chemistry 20040519

A Kunitz-type inhibitor of coleopteran proteases, isolated from Adenanthera pavonina L. seeds and its effect on Callosobruchus maculatus.

Journal of agricultural and food chemistry 20040505

Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.

Biophysical journal 20040501

Kinetics of parasite cysteine proteinase inactivation by NO-donors.

Biochemical and biophysical research communications 20040312

Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.

The Biochemical journal 20040301

The N-terminus moiety of the cystatin SmCys from Schistosoma mansoni regulates its inhibitory activity in vitro and in vivo.

Molecular and biochemical parasitology 20040301

Debridement: controlling the necrotic/cellular burden.

Advances in skin & wound care 20040301

Sequential Development of Cysteine Proteinase Activities and Gene Expression during Somatic Embryogenesis in Carrot.

Bioscience, biotechnology, and biochemistry 20040301

[Immobilization and stabilization of papain on SiO2 particles containing amine groups].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040301

Structural basis of the unusual stability and substrate specificity of ervatamin C, a plant cysteine protease from Ervatamia coronaria.

Biochemistry 20040217

Regulation of collagenase activities of human cathepsins by glycosaminoglycans.

The Journal of biological chemistry 20040213

The ribbon of hydrogen bonds in globular proteins. IV. The example of the papain family.

Biopolymers 20040205

Production and activation of recombinant papain-like cysteine proteases.

Methods (San Diego, Calif.) 20040201

Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex.

The Plant journal : for cell and molecular biology 20040201

Thiirancarboxamides as inhibitors of papain.

Archiv der Pharmazie 20040201

Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability.

Biomaterials 20040101

Activity of immobilized papain dehydrated by n-propanol in low-water media.

Biotechnology letters 20040101

Molecular and biochemical assays of cartilage components.

Methods in molecular medicine 20040101

Insight into catalytic mechanism of papain-like cysteine proteinases: the case of D158.

Applied biochemistry and biotechnology 20040101

Characterization of free aromatic amino acids and estimation of exposition rate of phenylalanine in casein hydrolysates by second derivative spectrophotometry.

Acta cientifica venezolana 20040101

Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several cell types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs.

The Journal of general virology 20031201

Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.

The Journal of biological chemistry 20031128

Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

The Journal of biological chemistry 20031114

Purification and properties of cysteine proteinase inhibitors from rabbit skeletal muscle.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001

Grafting of features of cystatins C or B into the N-terminal region or second binding loop of cystatin A (stefin A) substantially enhances inhibition of cysteine proteinases.

Biochemistry 20030930

Applying the increase in rate constants of cooperative proteolysis to the determination of transition curves of protein denaturation.

Journal of biochemical and biophysical methods 20030930

Ca2+ binding to myosin regulatory light chain affects the conformation of the N-terminus of essential light chain and its binding to actin.

Archives of biochemistry and biophysics 20030915

Mechanisms and enzymes involved in SARS coronavirus genome expression.

The Journal of general virology 20030901

Electrostatic properties in the catalytic site of papain: A possible regulatory mechanism for the reactivity of the ion pair.

Proteins 20030801

Processing and subcellular localization of the leader papain-like proteinase of Beet yellows closterovirus.

The Journal of general virology 20030801

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.

Cell death and differentiation 20030801

Nontraditional wound care: A review of the evidence for the use of sugar, papaya/papain, and fatty acids.

Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20030701

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems.

Biological chemistry 20030701

Variation in the pH-dependent pre-steady-state and steady-state kinetic characteristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion.

The Biochemical journal 20030615

Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment.

Journal of agricultural and food chemistry 20030604

AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death.

European journal of biochemistry 20030601

Enzymatic synthesis and characterization of l-methionine and 2-hydroxy-4-(methylthio)butanoic acid (HMB) co-oligomers.

Journal of agricultural and food chemistry 20030423

Enzymatic synthesis of a CCK-4 tripeptide fragment.

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030401

Human eosinophils are activated by cysteine proteases and release inflammatory mediators.

The Journal of allergy and clinical immunology 20030401

Proteolytic enzyme conjugated to SC-glucan as an enzymatic transdermal drug penetration enhancer.

Die Pharmazie 20030401

Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS.

Biological chemistry 20030401

[X-ray microanalysis of the activity of immobilized papain].

Guang pu xue yu guang pu fen xi = Guang pu 20030401

The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2.

Endocrinology 20030301

N-terminal domain unfolds first in the sequential unfolding of papain.

Protein and peptide letters 20030201

Contributions of individual residues in the N-terminal region of cystatin B (stefin B) to inhibition of cysteine proteinases.

Biochimica et biophysica acta 20030131

Oriented versus random protein immobilization.

Journal of biochemical and biophysical methods 20030131

Frog saccular hair cells dissociated with protease VIII exhibit inactivating BK currents, K(V) currents, and low-frequency electrical resonance.

Hearing research 20030101

Morrenain b I, a papain-like endopeptidase from the latex of Morrenia brachystephana Griseb. (Asclepiadaceae).

Journal of protein chemistry 20030101

New cysteine protease inhibitors in physiological secretory fluids and their medical significance.

Advances in enzyme regulation 20030101

Properties of chemically oxidized kininogens.

Acta biochimica Polonica 20030101

Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets?

Biochemical Society symposium 20030101

[Interaction of human factor X with thromboplastin].

Biomeditsinskaia khimiia 20030101

Design and synthesis of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one derivatives as cysteine proteases inhibitors.

Bioorganic & medicinal chemistry letters 20021202

Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design.

Chemical reviews 20021201

Occurrence and structural characterization of versican-like proteoglycan in human vitreous.

Biochimie 20021201

[The preparation and identification of rabbit's antibody of chymopapain].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021201

Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.

The Biochemical journal 20021115

Overlapping binding sites for trypsin and papain on a Kunitz-type proteinase inhibitor from Prosopis juliflora.

Proteins 20021115

Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.

Journal of medicinal chemistry 20021107

Preparation and characterization of papain-modified sesame (Sesamum indicum L.) protein isolates.

Journal of agricultural and food chemistry 20021106

Protein engineering of nitrile hydratase activity of papain: molecular dynamics study of a mutant and wild-type enzyme.

Journal of the American Chemical Society 20021106

A randomized paired comparison trial of cutaneous treatments for acute jellyfish (Carybdea alata) stings.

The American journal of emergency medicine 20021101

Application potency of engineered G159 mutants on P1 substrate pocket of subtilisin YaB as improved meat tenderizers.

Journal of agricultural and food chemistry 20021009

Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design.

Chemistry & biology 20021001

Foot-and-mouth disease virus leader proteinase: a papain-like enzyme requiring an acidic environment in the active site.

FEBS letters 20020925

Enhancement of proteinase inhibitory activity of recombinant human cystatin C using random-centroid optimization.

Biochimica et biophysica acta 20020923

The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators.

Journal of molecular biology 20020920

A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

The Biochemical journal 20020915

Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases.

Journal of medicinal chemistry 20020912

Cysteine proteinase inhibitors in elapid and hydrophiid snake venoms.

Toxicon : official journal of the International Society on Toxinology 20020901

The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells.

Biochemistry 20020820

Production, properties and specificity of a new bacterial L-fucose- and D-arabinose-binding lectin of the plant aggressive pathogen Ralstonia solanacearum, and its comparison to related plant and microbial lectins.

Journal of biochemistry 20020801

Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors.

Biochemistry 20020716

Enzymatic hydrolysis of nitriles by an engineered nitrile hydratase (papain Gln19Glu) in aqueous-organic media.

Biotechnology and bioengineering 20020705

Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.

Analytical and bioanalytical chemistry 20020701

Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the healthpoint system in the management of pressure ulcers.

Annals of plastic surgery 20020701

Calcium modulates protease resistance and carbohydrate binding of a plant defense legume lectin, Griffonia simplicifolia lectin II (GSII).

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601

Affinity of chicken cystatin for S-(carbamoylmethyl)-papain, measured by fluorescence at acidic pH.

Protein and peptide letters 20020601

Effect of urea at lower concentration on the structure of papain--formation of a stable molten globule and its characterization.

Indian journal of biochemistry & biophysics 20020601

The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.

The Biochemical journal 20020515

Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.

The Biochemical journal 20020501

Galactosaminoglycan composition in chicken eggshell.

Poultry science 20020501

A 40-kDa polypeptide from papain digestion of the rabbit intestinal Na+/phosphate cotransporter retains Na+ and phosphate cotransport.

Archives of biochemistry and biophysics 20020501

Red blood cells stimulate fibroblast-mediated contraction of three dimensional collagen gels in co-culture.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020501

Are PhAcOZ and Nsc suitable N alpha-protecting groups for protease-catalysed peptide synthesis?

Die Pharmazie 20020501

Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases.

Biochemistry 20020416

Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.

The Journal of biological chemistry 20020412

Conformational analysis of the GTP-binding protein MxA using limited proteolysis.

FEBS letters 20020410

Topology of the anion exchange protein AE1: the controversial sidedness of lysine 743.

Biochemistry 20020312

[Characterization of peptide and amino acid profile in casein hydrolysates].

Archivos latinoamericanos de nutricion 20020301

Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation.

The Journal of biological chemistry 20020222

Stabilization of molten globule state of papain by urea.

Biochemical and biophysical research communications 20020208

Cysteine protease gene expression and proteolytic activity during senescence of Alstroemeria petals.

Journal of experimental botany 20020201

Effect of metal ions on structure and activity of papain from Carica papaya.

Die Nahrung 20020201

A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage.

Analytical biochemistry 20020101

The Arabidopsis xylem peptidase XCP1 is a tracheary element vacuolar protein that may be a papain ortholog.

Plant physiology 20020101

Characterizing closely spaced, complex disulfide bond patterns in peptides and proteins by liquid chromatography/electrospray ionization tandem mass spectrometry.

Journal of mass spectrometry : JMS 20020101

Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester.

Biomacromolecules 20020101

Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101

The effects of the interaction of myosin essential light chain isoforms with actin in skeletal muscles.

Acta biochimica Polonica 20020101

Synthesis and biological properties of antitumor-active conjugates of ADR with dextran.

Journal of biomaterials science. Polymer edition 20020101

Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101

[Effect of shenmai injection and aminophylline on small airway smooth muscle cell apoptosis and related gene expression in rats with emphysema].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020101

Synthesis of cholecystokinin peptide CCK-4 exclusively by enzymatic methods.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

[Characterization of cysteine proteinase endogenous inhibitors obtained from transformed fibroblasts].

Voprosy meditsinskoi khimii 20020101

[Reactions of derivatives of beta-lactam antibiotics with non-antibacterial biological activity].

Acta pharmaceutica Hungarica 20020101

Kinetics of modulation of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels by tetramethrin and deltamethrin.

The Journal of pharmacology and experimental therapeutics 20011201

Studies on the inactivation of soluble and immobilized papain by the ascorbic acid-Cu2+ system: a model to propose the effect of free radicals on membrane-bound enzymes in vivo.

Biotechnology and applied biochemistry 20011201

Identification, characterization and localization of chagasin, a tight-binding cysteine protease inhibitor in Trypanosoma cruzi.

Journal of cell science 20011101

Broad specificity alkaline proteases efficiently reduce the visual scaling associated with soap-induced xerosis.

Archives of dermatological research 20011101

Electrostatic recognition between enzyme and inhibitor: interaction between papain and leupeptin.

Archives of biochemistry and biophysics 20011015

Rapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cells.

The Journal of physiology 20011001

Domain-domain interactions of HtpG, an Escherichia coli homologue of eukaryotic HSP90 molecular chaperone.

European journal of biochemistry 20011001

The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs.

Biological chemistry 20011001

Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.

The Journal of biological chemistry 20010928

Proteinase activity in the white shrimp (Penaeus vannamei) clotting protein.

Biochemical and biophysical research communications 20010921

Vinyl sulfonium as novel proteolytic enzyme inhibitor.

Bioorganic & medicinal chemistry letters 20010903

Lysosomal cysteine proteases: facts and opportunities.

The EMBO journal 20010903

Interactions of human lacrimal and salivary cystatins with adenovirus endopeptidase.

Antiviral research 20010901

Role of the single cysteine residue, Cys 3, of human and bovine cystatin B (stefin B) in the inhibition of cysteine proteinases.

Protein science : a publication of the Protein Society 20010901

Channel cytoplasmic loops alter voltage-dependent sodium channel activation in an isoform-specific manner.

The Journal of physiology 20010901

Phage display selection of hairpin loop soyacystatin variants that mediate high affinity inhibition of a cysteine proteinase.

The Plant journal : for cell and molecular biology 20010901

The reaction of serpins with proteinases involves important enthalpy changes.

Biochemistry 20010821

Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases.

FEBS letters 20010803

Box jellyfish (Carybdea alata) in Waikiki. The analgesic effect of sting-aid, Adolph's meat tenderizer and fresh water on their stings: a double-blinded, randomized, placebo-controlled clinical trial.

Hawaii medical journal 20010801

Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.

The Biochemical journal 20010715

Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.

Cancer chemotherapy and pharmacology 20010701

Retrolective cohort study of an additive therapy with an oral enzyme preparation in patients with multiple myeloma.

Cancer chemotherapy and pharmacology 20010701

Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.

The Journal of biological chemistry 20010601

Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.

Analytical biochemistry 20010601

Inhibition of cysteine protease activity by NO-donors.

Current protein & peptide science 20010601

Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors.

The Journal of biological chemistry 20010511

Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X.

Biochimica et biophysica acta 20010505

Counting the number of disulfides and thiol groups in proteins and a novel approach for determining the local pKa for cysteine groups in proteins in vivo.

Journal of synchrotron radiation 20010501

Fragmentation of immunoglobulin G.

Current protocols in immunology 20010501

The theory and application of transition state pK(a) values: the reaction of papain with a series of trimethylene disulphide reactivity probes.

Journal of theoretical biology 20010421

Insight into the catalysis of hydrolysis of four newly synthesized substrates by papain: a proton inventory study.

Biochemistry 20010403

Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism.

Cellular and molecular life sciences : CMLS 20010401

Molecular cloning and functional expression of cDNA encoding the cysteine proteinase inhibitor Sca from sunflower seeds.

Bioscience, biotechnology, and biochemistry 20010401

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

Current biology : CB 20010320

Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain family.

The Journal of biological chemistry 20010316

Paramyxovirus fusion (F) protein: a conformational change on cleavage activation.

Virology 20010301

S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.

European journal of biochemistry 20010301

A constitutive cystatin-encoding gene from barley (Icy) responds differentially to abiotic stimuli.

Plant molecular biology 20010301

A cystatin-based affinity procedure for the isolation and analysis of papain-like cysteine proteinases from tissue extracts.

Analytical biochemistry 20010215

Papain immobilization on a nitrilon fibre carrier containing primary amine groups.

Biotechnology and applied biochemistry 20010201

Interaction of cysteine proteases with calciotropic hormone receptors.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010201

Papain does not cleave operator-bound lambda repressor: structural characterization of the carboxy terminal domain and the hinge.

Journal of biomolecular structure & dynamics 20010201

Complex effects of papain on function and inhibitor sensitivity of the red cell anion exchanger AE1 suggest the presence of different transport subsites.

The Journal of membrane biology 20010201

High-level production of recombinant chicken cystatin by Pichia pastoris and its application in mackerel surimi.

Journal of agricultural and food chemistry 20010201

Identification of a membrane-associated cysteine protease with possible dual roles in the endoplasmic reticulum and protein storage vacuole.

The Journal of biological chemistry 20010105

Modification of cyclosporin A and conjugation of its derivative to HPMA copolymers.

Bioconjugate chemistry 20010101

Protons inhibit the BK(Ca) channel of rat small artery smooth muscle cells.

Journal of vascular research 20010101

[Anti-inflammatory activity of domestic papain].

Eksperimental'naia i klinicheskaia farmakologiia 20010101

The combined treatment of transplantable solid mammary carcinoma in Wistar rats by use of photodynamic therapy and cysteine proteinase inhibitor.

In vivo (Athens, Greece) 20010101

Immobilization of papain on cold-plasma functionalized polyethylene and glass surfaces.

Journal of biomaterials science. Polymer edition 20010101

Excitability in chemical and biochemical pH-autocatalytic systems.

Faraday discussions 20010101

Influence of organic solvents on papain kinetics.

Acta biochimica Polonica 20010101

Influence of Me2SO and incubation time on papain activity studied using fluorogenic substrates.

Acta biochimica Polonica 20010101

Synthesis of some pseudo-peptide analogs of thiol proteinase inhibitors.

Chemical & pharmaceutical bulletin 19990301

Chromogenic and fluorogenic glycosylated and acetylglycosylated peptides as substrates for serine, thiol and aspartyl proteases.

The journal of peptide research : official journal of the American Peptide Society 19990201

Domain structure and conformation of a cellobiohydrolase from Trichoderma pseudokiningii S-38.

Journal of protein chemistry 19970101

Amino acids and peptides. XXVIII. Preparation of poly(ethylene glycol) hybrids of Gln-Val-Val-Ala-Gly analogs and their inhibitory effect on papain.

Biological & pharmaceutical bulletin 19960601

Separation of functional domains for the alpha-1,4 and alpha-1,6 hydrolytic activities of a Bacillus amylopullulanase by limited proteolysis with papain.

Bioscience, biotechnology, and biochemistry 19960401

Interaction of ebselen with glutathione S-transferase and papain in vitro.

Biochemical pharmacology 19940315

Peptide production by a combination of gene expression, chemical synthesis, and protease-catalyzed conversion.

International journal of peptide and protein research 19930401

Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors.

Biochemistry 19921124

Papain-inhibitory activity of oryzacystatin, a rice seed cysteine proteinase inhibitor, depends on the central Gln-Val-Val-Ala-Gly region conserved among cystatin superfamily members.

Journal of biochemistry 19910201

An efficient chemical-enzymatic synthesis of LHRH N-terminal pentapeptide.

Biomedica biochimica acta 19910101

A methodological study of the enzymatic synthesis of the tripeptide Z-Cys(Bzl)-Tyr-Ile-OtBu.

Peptide research 19910101

The NH2-terminal 21 amino acid residues are not essential for the papain-inhibitory activity of oryzacystatin, a member of the cystatin superfamily. Expression of oryzacystatin cDNA and its truncated fragments in Escherichia coli.

The Journal of biological chemistry 19880605

Amino acids and peptides. XX. Inhibition of papain by succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide, a common sequence of endogenous thiol proteinase inhibitors.

Chemical & pharmaceutical bulletin 19880601

Significant effects of Z-Gln-Val-Val-OME, common sequences of thiol proteinase inhibitors on thiol proteinases.

Biochemical and biophysical research communications 19870313

Structural studies and two-dimensional gel electrophoresis of gamma-glutamyl transpeptidase.

Archives of biochemistry and biophysics 19860515

Carboxyl-modified amino acids and peptides as protease inhibitors.

Journal of medicinal chemistry 19860101

Significant effects of synthetic Gln-Val-Val-Ala-Gly and its derivatives, common sequences of thiol proteinase inhibitors, on thiol proteinase.

Chemical & pharmaceutical bulletin 19851101

Case report. Immunological studies in a case of hepatitis following methyldopa administration.

The American journal of the medical sciences 19790101

The pKa value of the active site histidine in photo-oxidised papain.

FEBS letters 19760101

The effect of acid treatment upon the susceptibility of rabbit IgG to proteolytic cleavage with various enzymes.

Immunochemistry 19750801

9001-73-4 | Papain

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