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89-00-9 | Quinolinic acid
CAS No: 89-00-9 Catalog No: AG00IFJS MDL No:MFCD00006295
Product Description
Catalog Number:
AG00IFJS
Chemical Name:
Quinolinic acid
CAS Number:
89-00-9
MDL Number:
MFCD00006295
IUPAC Name:
pyridine-2,3-dicarboxylic acid
InChI:
InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)
InChI Key:
GJAWHXHKYYXBSV-UHFFFAOYSA-N
EC Number:
201-874-8
UNII:
F6F0HK1URN
Properties
Complexity:
204
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
167.022g/mol
Formal Charge:
0
Heavy Atom Count:
12
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
167.12g/mol
Monoisotopic Mass:
167.022g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
87.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2
Literature
| Title | Journal |
|---|---|
| Quinolinic acid and glutamatergic neurodegeneration in Caenorhabditis elegans. | Neurotoxicology 20180701 |
| Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor. | Toxicology and applied pharmacology 20170515 |
| The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations. | Journal of the neurological sciences 20121215 |
| Mitochondrial disturbances, excitotoxicity, neuroinflammation and kynurenines: novel therapeutic strategies for neurodegenerative disorders. | Journal of the neurological sciences 20121115 |
| Targeting neuro-inflammatory cytokines and oxidative stress by minocycline attenuates quinolinic-acid-induced Huntington's disease-like symptoms in rats. | Neurotoxicity research 20121101 |
| Protective effect of N,N'-dialkylated analogs of 4,4'-diaminodiphenylsulfone in a model of intrastriatal quinolinic acid induced-excitotoxicity. | Neuroscience letters 20121018 |
| Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20121001 |
| Topological difference in 2D layers steers the formation of rigid and flexible 3D supramolecular isomers: impact on the adsorption properties. | Inorganic chemistry 20120903 |
| Effects of hypoxia-inducible factor 1α on bone conduction impairment in otitis media with effusion. | Acta oto-laryngologica 20120901 |
| Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid. | Neurochemical research 20120901 |
| Neuroprotective effects and magnetic resonance imaging of mesenchymal stem cells labeled with SPION in a rat model of Huntington's disease. | Stem cell research 20120901 |
| The synthesis, spectroscopic, X-ray characterization and in vitro cytotoxic testing results of activity of five new trans-platinum(IV) complexes with functionalized pyridines. | European journal of medicinal chemistry 20120901 |
| Two new palladium(II) complexes: synthesis, characterization and their interaction with HeLa cells. | Dalton transactions (Cambridge, England : 2003) 20120828 |
| The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. | Trends in parasitology 20120801 |
| Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis. | FEBS letters 20120730 |
| Studies of inhibitor binding to the [4Fe-4S] cluster of quinolinate synthase. | Angewandte Chemie (International ed. in English) 20120727 |
| Loss of neuron-astroglial interaction rapidly induces protective CNTF expression after stroke in mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120704 |
| Weak BMAA toxicity compares with that of the dietary supplement β-alanine. | Neurobiology of aging 20120701 |
| In vivo detection of excitotoxicity by manganese-enhanced MRI: comparison with physiological stimulation. | Magnetic resonance in medicine 20120701 |
| Selenium-induced antioxidant protection recruits modulation of thioredoxin reductase during excitotoxic/pro-oxidant events in the rat striatum. | Neurochemistry international 20120701 |
| Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine. | Current HIV research 20120701 |
| Kynurenines in the mammalian brain: when physiology meets pathology. | Nature reviews. Neuroscience 20120701 |
| Two new Co(II) coordination polymers based on carboxylate-bridged di- and trinuclear clusters with a pyridinedicarboxylate ligand: synthesis, structures and magnetism. | Dalton transactions (Cambridge, England : 2003) 20120614 |
| Social isolation rearing in rats alters plasma tryptophan metabolism and is reversed by sub-chronic clozapine treatment. | Neuropharmacology 20120601 |
| A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain. | Neurobiology of disease 20120601 |
| Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy. | Journal of neuroscience research 20120601 |
| Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120601 |
| Post-training unilateral amygdala lesions selectively impair contextual fear memories. | Learning & memory (Cold Spring Harbor, N.Y.) 20120521 |
| A complementary diffusion tensor imaging (DTI)-histological study in a model of Huntington's disease. | Neurobiology of aging 20120501 |
| Inhibition of acetylcholinesterase activities and some pro-oxidant induced lipid peroxidation in rat brain by two varieties of ginger (Zingiber officinale). | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120501 |
| Evaluation of a multiple system atrophy model in rats using multitracer microPET. | Acta neurochirurgica 20120501 |
| Inducible NAD overproduction in Arabidopsis alters metabolic pools and gene expression correlated with increased salicylate content and resistance to Pst-AvrRpm1. | The Plant journal : for cell and molecular biology 20120501 |
| Peculiarities of intramolecular exchange and valence tautomerism in metal semiquinolates determined by high-resolution NMR spectroscopy. | Magnetic resonance in chemistry : MRC 20120501 |
| Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats. | Journal of clinical biochemistry and nutrition 20120501 |
| Poly[[chloridodimethanol(μ(3)-pyridine-2,3-dicarboxyl-ato)europium(III)] methanol monosolvate]. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Towards a new family of photoluminescent organozinc 8-hydroxyquinolinates with a high propensity to form noncovalent porous materials. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120427 |
| Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. | Cell stem cell 20120406 |
| Quinolinic acid, the inescapable neurotoxin. | The FEBS journal 20120401 |
| Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection. | The FEBS journal 20120401 |
| Quinolinic acid: neurotoxicity. | The FEBS journal 20120401 |
| The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders. | The FEBS journal 20120401 |
| Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity: a potential therapy for Huntington's disease. | Experimental neurology 20120401 |
| Kynurenines: from the perspective of major psychiatric disorders. | The FEBS journal 20120401 |
| Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato)zincate(II) trihydrate. | Acta crystallographica. Section E, Structure reports online 20120401 |
| Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro. | Brain research bulletin 20120310 |
| Nicotinamide dependence of uropathogenic Escherichia coli UTI89 and application of nadB as a neutral insertion site. | Microbiology (Reading, England) 20120301 |
| Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure. | Journal of inorganic biochemistry 20120301 |
| Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder. | Journal of psychopharmacology (Oxford, England) 20120301 |
| Potato- an important source of nutritional kynurenic acid. | Plant foods for human nutrition (Dordrecht, Netherlands) 20120301 |
| Bis[[aqua-(1H-imidazo[4,5-f][1,10]phenanthroline-κN,N)cadmium]bis-(μ-pyridine-2,3-dicarboxyl-ato)-κN,O:O;κO:N,O]. | Acta crystallographica. Section E, Structure reports online 20120301 |
| Gas chromatography/tandem mass spectrometry detection of extracellular kynurenine and related metabolites in normal and lesioned rat brain. | Analytical biochemistry 20120215 |
| Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum. | ACS chemical neuroscience 20120215 |
| Regulation of quinolinic acid neosynthesis in mouse, rat and human brain by iron and iron chelators in vitro. | Journal of neural transmission (Vienna, Austria : 1996) 20120201 |
| ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice. | Neurochemical research 20120201 |
| Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3. | Pharmacological research 20120201 |
| Strong association of phenylalanine and tryptophan metabolites with activated cytomegalovirus infection in kidney transplant recipients. | Human immunology 20120201 |
| Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. | Molecular neurobiology 20120201 |
| A validated CE method for determining dimethylsulfate a carcinogen and chloroacetyl chloride a potential genotoxin at trace levels in drug substances. | Journal of pharmaceutical and biomedical analysis 20120125 |
| Nucleus accumbens and delay discounting in rats: evidence from a new quantitative protocol for analysing inter-temporal choice. | Psychopharmacology 20120101 |
| Signaling mechanisms downstream of quinolinic acid targeting the cytoskeleton of rat striatal neurons and astrocytes. | Experimental neurology 20120101 |
| Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice. | Journal of neuroinflammation 20120101 |
| Poly[[hexa-aqua-(μ(2)-oxalato-κO,O:O,O)bis(μ(3)-pyridine-2,4-dicarboxyl-ato-κN,O:O:O)dicerium(III)] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20120101 |
| Bis-(μ-pyridine-2,3-dicarboxyl-ato)bis-[aqua-(3-carb-oxy-pyridine-2-carboxyl-ato)indium(III)] tetra-hydrate. | Acta crystallographica. Section E, Structure reports online 20120101 |
| Nucleic Acid-Based Therapy Approaches for Huntington's Disease. | Neurology research international 20120101 |
| Modulation of tumor tolerance in primary central nervous system malignancies. | Clinical & developmental immunology 20120101 |
| Single nucleotide polymorphism in gene encoding transcription factor Prep1 is associated with HIV-1-associated dementia. | PloS one 20120101 |
| Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. | BMJ open 20120101 |
| The visinin-like proteins VILIP-1 and VILIP-3 in Alzheimer's disease-old wine in new bottles. | Frontiers in molecular neuroscience 20120101 |
| Essential role of excessive tryptophan and its neurometabolites in fatigue. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20120101 |
| Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms. | International journal of tryptophan research : IJTR 20120101 |
| Encapsulated cell-based biodelivery of meteorin is neuroprotective in the quinolinic acid rat model of neurodegenerative disease. | Restorative neurology and neuroscience 20120101 |
| In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function. | PloS one 20120101 |
| Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex. | PloS one 20120101 |
| Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. | Surgical neurology international 20120101 |
| The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness. | Frontiers in behavioral neuroscience 20120101 |
| Generation and applications of human pluripotent stem cells induced into neural lineages and neural tissues. | Frontiers in physiology 20120101 |
| Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections. | PloS one 20120101 |
| Effects of memantine, an N-methyl-D-aspartate receptor antagonist, on fatigue and neuronal brain damage in a rat model of combined (physical and mental) fatigue. | Biological & pharmaceutical bulletin 20120101 |
| Ru complexes containing pyridine dicarboxylate ligands: electronic effects on their catalytic activity toward water oxidation. | Faraday discussions 20120101 |
| Treatment with a substance P receptor antagonist is neuroprotective in the intrastriatal 6-hydroxydopamine model of early Parkinson's disease. | PloS one 20120101 |
| Potentials of endogenous neural stem cells in cortical repair. | Frontiers in cellular neuroscience 20120101 |
| Restoration of the striatal circuitry: from developmental aspects toward clinical applications. | Frontiers in cellular neuroscience 20120101 |
| A jerte valley cherry-based product as a supply of tryptophan. | International journal of tryptophan research : IJTR 20120101 |
| Chronic traumatic encephalopathy: a review. | Rehabilitation research and practice 20120101 |
| Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases. | Frontiers in pharmacology 20120101 |
| Fatigue in patients with lung cancer is related with accelerated tryptophan breakdown. | PloS one 20120101 |
| Drosophila eye color mutants as therapeutic tools for Huntington disease. | Fly 20120101 |
| M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. | PloS one 20120101 |
| Striatal input- and rate-dependent effects of muscarinic receptors on pallidal firing. | TheScientificWorldJournal 20120101 |
| A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome. | Frontiers in pharmacology 20120101 |
| The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. | Oxidative medicine and cellular longevity 20120101 |
| Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis. | PloS one 20120101 |
| Picolinic acid in patients with chronic hepatitis C infection: a preliminary report. | Mediators of inflammation 20120101 |
| Microglia and drug-induced plasticity in reward-related neuronal circuits. | Frontiers in molecular neuroscience 20120101 |
| Tryptophan catabolism is associated with acute GVHD after human allogeneic stem cell transplantation and indicates activation of indoleamine 2,3-dioxygenase. | Blood 20111222 |
| The neurodegenerative process in a neurotoxic rat model and in patients with Huntington's disease: histopathological parallels and differences. | Acta histochemica 20111201 |
| Structure and electronic properties of Alq3 derivatives with electron acceptor/donor groups at the C4 positions of the quinolate ligands: a theoretical study. | Journal of molecular modeling 20111201 |
| Quinolinic acid lesions of the pedunculopontine nucleus impair sleep architecture, but not locomotion, exploration, emotionality or working memory in the rat. | Behavioural brain research 20111201 |
| Impaired sensitivity to Pavlovian stimulus-outcome learning after excitotoxic lesion of the ventrolateral neostriatum. | Behavioural brain research 20111201 |
| Intracerebroventricular administration of inosine is anticonvulsant against quinolinic acid-induced seizures in mice: an effect independent of benzodiazepine and adenosine receptors. | Pharmacology, biochemistry, and behavior 20111201 |
| Poly[[hexa-aqua-(μ(2)-oxalato-κO,O:O,O)bis-(μ(3)-pyridine-2,4-dicarboxyl-ato-κN,O:O:O)dilanthanum(III)] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20111201 |
| Proteome studies on liver tissue in a phenobarbital-induced rat model. | European journal of pharmacology 20111130 |
| Bone marrow derived mesenchymal stem cell transplantation in cerebellar degeneration: a behavioral study. | Behavioural brain research 20111120 |
| Altered tryptophan metabolism in Parkinson's disease: a possible novel therapeutic approach. | Journal of the neurological sciences 20111115 |
| Contamination of mesenchymal stem-cells with fibroblasts accelerates neurodegeneration in an experimental model of Parkinson's disease. | Stem cell reviews 20111101 |
| Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide. | Alcohol and alcoholism (Oxford, Oxfordshire) 20111101 |
| Tryptophan in alcoholism treatment I: kynurenine metabolites inhibit the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevate blood acetaldehyde concentration and induce aversion to alcohol. | Alcohol and alcoholism (Oxford, Oxfordshire) 20111101 |
| Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats. | The FEBS journal 20111101 |
| Neuroprotective effects of mesenchymal stem cell transplantation in animal model of cerebellar degeneration. | Neurological research 20111101 |
| Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe and NADPH. | Journal of clinical biochemistry and nutrition 20111101 |
| Research on an in vitro cell system for testing the neurotoxicity of kynurenine pathway metabolites. | Die Pharmazie 20111101 |
| 6,6'-(Pyridine-2,6-di-yl)bis-(pyrrolo-[3,4-b]pyridine-5,7-dione). | Acta crystallographica. Section E, Structure reports online 20111101 |
| Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid. | Life sciences 20111010 |
| Molecular evolution of bacterial indoleamine 2,3-dioxygenase. | Gene 20111001 |
| Human myeloid dendritic cells are refractory to tryptophan metabolites. | Human immunology 20111001 |
| Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line. | Plant physiology and biochemistry : PPB 20111001 |
| Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction. | American journal of physiology. Heart and circulatory physiology 20111001 |
| Unsaturated iridium pyridinedicarboxylate pincer complexes with catalytic activity in borylation of arenes. | Dalton transactions (Cambridge, England : 2003) 20110907 |
| Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis. | Journal of neurochemistry 20110901 |
| Targeting the kynurenine pathway as a potential strategy to prevent and treat Alzheimer's disease. | Medical hypotheses 20110901 |
| The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1. | The American journal of pathology 20110901 |
| Systemic changes of tryptophan catabolites via the indoleamine-2,3-dioxygenase pathway in primary cervical cancer. | Anticancer research 20110801 |
| An integrated approach to characterize genetic interaction networks in yeast metabolism. | Nature genetics 20110701 |
| In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110701 |
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| Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110601 |
| Chloridobis(2-chloro-benz-yl)(quinolin-8-olato-κN,O)tin(IV). | Acta crystallographica. Section E, Structure reports online 20110601 |
| 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues? | Toxins 20110601 |
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| NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways. | Behavioural brain research 20110516 |
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| Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
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| Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer. | Omics : a journal of integrative biology 20110501 |
| Proneural transcription factors Dlx2 and Pax6 are altered in adult SVZ neural precursor cells following striatal cell loss. | Molecular and cellular neurosciences 20110501 |
| catena-Poly[diimidazolium [bis-(μ-pyridine-2,5-dicarboxyl-ato)bis-[diaqua-praseodymate(III)]]-bis-(μ-pyridine-2,5-dicarboxyl-ato)]. | Acta crystallographica. Section E, Structure reports online 20110501 |
| Piperazine-1,4-diium pyridine-2,3-dicarboxyl-ate methanol monosolvate. | Acta crystallographica. Section E, Structure reports online 20110501 |
| The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression. | Progress in neuro-psychopharmacology & biological psychiatry 20110429 |
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| Structure and reaction mechanism in the heme dioxygenases. | Biochemistry 20110412 |
| Inflammation-associated depression: from serotonin to kynurenine. | Psychoneuroendocrinology 20110401 |
| γ-Aminobutyric acid type B receptor changes in the rat striatum and substantia nigra following intrastriatal quinolinic acid lesions. | Journal of neuroscience research 20110401 |
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| Licofelone attenuates quinolinic acid induced Huntington like symptoms: possible behavioral, biochemical and cellular alterations. | Progress in neuro-psychopharmacology & biological psychiatry 20110330 |
| Inflammation in depression: is adiposity a cause? | Dialogues in clinical neuroscience 20110301 |
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| Identifying chelators for metalloprotein inhibitors using a fragment-based approach. | Journal of medicinal chemistry 20110127 |
| Heteronuclear (Co-Ca, Co-Ba) 2,3-pyridinedicarboxylate complexes: synthesis, structure and physico-chemical properties. | Dalton transactions (Cambridge, England : 2003) 20110114 |
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| Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model. | Neurobiology of disease 20110101 |
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| Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD). | Molecular neurodegeneration 20110101 |
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| The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment. | Journal of neuroinflammation 20110101 |
| Vascular pathology and blood-brain barrier disruption in cognitive and psychiatric complications of type 2 diabetes mellitus. | Cardiovascular psychiatry and neurology 20110101 |
| Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO). | PloS one 20110101 |
| An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons. | Toxicologic pathology 20110101 |
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| Environmental enrichment facilitates long-term potentiation in embryonic striatal grafts. | Neurorehabilitation and neural repair 20110101 |
| The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice. | PloS one 20110101 |
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| Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. | PloS one 20110101 |
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| Toward an anti-inflammatory strategy for depression. | Frontiers in behavioral neuroscience 20110101 |
| Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome. | BMC medical genomics 20110101 |
| Tryptophan degradation in women with breast cancer: a pilot study. | BMC research notes 20110101 |
| Intragenomic diversity of Rhizobium leguminosarum bv. trifolii clover nodule isolates. | BMC microbiology 20110101 |
| The metabolic advantage of tumor cells. | Molecular cancer 20110101 |
| Risk factors for the development of depression in patients with hepatitis C taking interferon-α. | Neuropsychiatric disease and treatment 20110101 |
| The involvement of neuroinflammation and kynurenine pathway in Parkinson's disease. | Parkinson's disease 20110101 |
| Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease. | Frontiers in systems neuroscience 20110101 |
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| Liver Metabolic Alterations and Changes in Host Intercompartmental Metabolic Correlation during Progression of Malaria. | Journal of parasitology research 20110101 |
| A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase. | Neuropsychiatric disease and treatment 20110101 |
| HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner. | Journal of neuroinflammation 20110101 |
| Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? | Journal of neuroinflammation 20110101 |
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| Huntington's Disease and Striatal Signaling. | Frontiers in neuroanatomy 20110101 |
| 3-Hydroxy kynurenine treatment controls T. cruzi replication and the inflammatory pathology preventing the clinical symptoms of chronic Chagas disease. | PloS one 20110101 |
| Differential effects of accumbens core vs. shell lesions in a rat concurrent conditioned place preference paradigm for cocaine vs. social interaction. | PloS one 20110101 |
| Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis. | Molecular neurodegeneration 20110101 |
| Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo. | Marine drugs 20110101 |
| Tryptophan oxidative metabolism catalyzed by geobacillus stearothermophilus: a thermophile isolated from kuwait soil contaminated with petroleum hydrocarbons. | International journal of tryptophan research : IJTR 20110101 |
| Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons. | International journal of tryptophan research : IJTR 20110101 |
| Acetaminophen: beyond pain and Fever-relieving. | Frontiers in pharmacology 20110101 |
| Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT)-I/II null mutant mice. | Journal of neuroinflammation 20110101 |
| Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470. | International journal of molecular imaging 20110101 |
| Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide. | Journal of neuroinflammation 20110101 |
| Cytokine production by leukocytes of military personnel with depressive symptoms after deployment to a combat-zone: a prospective, longitudinal study. | PloS one 20110101 |
| Acetylcholine and memory-enhancing activity of Ficus racemosa bark. | Pharmacognosy research 20110101 |
| Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury. | PloS one 20110101 |
| Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System. | International journal of Alzheimer's disease 20110101 |
| Gold nanoparticles in biology and medicine: recent advances and prospects. | Acta naturae 20110101 |
| Near-infrared luminescence from visible-light-sensitized hybrid materials covalently linked with tris(8-hydroxyquinolinate)-lanthanide [Er(III), Nd(III), and Yb(III)] derivatives. | The journal of physical chemistry. B 20101216 |
| Type 1 cannabinoid receptor mapping with [18F]MK-9470 PET in the rat brain after quinolinic acid lesion: a comparison to dopamine receptors and glucose metabolism. | European journal of nuclear medicine and molecular imaging 20101201 |
| Dual role of the carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase: mitochondrial-targeting signal and enzymatic activity. | Journal of biochemistry 20101201 |
| Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington's disease. | CNS & neurological disorders drug targets 20101201 |
| Striatal ablation of GABAergic neurons prevents the in vivo neuroprotective effect of DCG-IV against the MPP+-induced neurotoxicity on dopaminergic nerve terminals. | Neurochemistry international 20101201 |
| Poly[hexa-aqua-hexa-kis-(μ-pyridine-2,4-dicarboxyl-ato)tricopper(II)dieuropium(III)]. | Acta crystallographica. Section E, Structure reports online 20101201 |
| Hexaaqua-zinc(II) bis-[tris-(3-carb-oxy-pyridine-2-carboxyl-ato)zincate(II)]. | Acta crystallographica. Section E, Structure reports online 20101201 |
| Poly[[triaqua-(μ(3)-4-oxidopyridine-2,6-dicarboxyl-ato)europium(III)] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20101201 |
| Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats. | Neuroscience 20101124 |
| Proteomic definition of the cell wall of Mycobacterium tuberculosis. | Journal of proteome research 20101105 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20101027 |
| Mechanism for the formation of substituted manganese(V) cyanidonitrido complexes: crystallographic and kinetic study of the substitution reactions of trans-[MnN(H2O)(CN)4]2- with monodentate pyridine and bidentate pyridine-carboxylate ligands. | Inorganic chemistry 20101018 |
| BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease. | Gene therapy 20101001 |
| Triimidazolium tris-(pyridine-2,6-di-carboxyl-ato)dysprosate(III) trihydrate. | Acta crystallographica. Section E, Structure reports online 20101001 |
| Quinolinate induces selective loss of melanin-concentrating hormone neurons, rather than orexin neurons, in the hypothalamus of mice and young rats. | Neuroscience 20100929 |
| Antiperoxidative and antiinflammatory effect of Sida cordifolia Linn. on quinolinic acid induced neurotoxicity. | Neurochemical research 20100901 |
| Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii. | PLoS genetics 20100901 |
| Molybdenum peroxo nanohybrid compounds in different structures and catalytic properties. | Journal of nanoscience and nanotechnology 20100901 |
| Molecular basis of vascular events following spinal cord injury. | Journal of medicine and life 20100815 |
| The kynurenine pathway and inflammation in amyotrophic lateral sclerosis. | Neurotoxicity research 20100801 |
| Synthesis, characterization, DNA interaction, and cytotoxicity of novel Pd(II) and Pt(II) complexes. | Journal of enzyme inhibition and medicinal chemistry 20100801 |
| Pioglitazone ameliorates behavioral, biochemical and cellular alterations in quinolinic acid induced neurotoxicity: possible role of peroxisome proliferator activated receptor-Upsilon (PPARUpsilon) in Huntington's disease. | Pharmacology, biochemistry, and behavior 20100801 |
| In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects. | Human molecular genetics 20100801 |
| Kynurenines, neurodegeneration and Alzheimer's disease. | Journal of cellular and molecular medicine 20100801 |
| Neuroprotective actions of the synthetic estrogen 17alpha-ethynylestradiol in the hippocampus. | Cellular and molecular neurobiology 20100701 |
| Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats. | Experimental neurology 20100701 |
| Lithium reduces apoptosis and autophagy after neonatal hypoxia-ischemia. | Cell death & disease 20100701 |
| Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression. | Behavioural brain research 20100626 |
| Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats. | Behavioural brain research 20100626 |
| PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells. | Brain research 20100622 |
| RAFT polymerization of luminescent boron quinolate monomers. | Chemical communications (Cambridge, England) 20100607 |
| Neurotoxicity of quinolinic acid to spiral ganglion cells in rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100601 |
| [Analysis of quinolinic acid neurotoxicity to excitability of spiral ganglion cells and its mechanism in rat]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100601 |
| Developmental regulation and neuroprotective effects of striatal tonic GABAA currents. | Neuroscience 20100519 |
| Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? | Brain : a journal of neurology 20100501 |
| On the early toxic effect of quinolinic acid: involvement of RAGE. | Neuroscience letters 20100426 |
| An analytical method for the measurement of acid metabolites of tryptophan-NAD pathway and related acids in urine. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415 |
| CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. | Molecular psychiatry 20100401 |
| Autonomic, behavioral, and neural analyses of mild conditioned negative affect in marmosets. | Behavioral neuroscience 20100401 |
| 4,4'-Bipyridinium bis-(μ-4-oxo-1,4-dihydropyridine-2,6-dicarboxyl-ato)bis-[aqua-hydroxido-anti-monate(III)] dihydrate. | Acta crystallographica. Section E, Structure reports online 20100401 |
| Biomarkers predicting progression of human immunodeficiency virus-related disease. | Journal of clinical medicine research 20100401 |
| Systemic transplantation of mesenchymal stem cells can reduce cognitive and motor deficits in rats with unilateral lesions of the neostriatum. | Neurological research 20100301 |
| Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock. | Scandinavian journal of infectious diseases 20100301 |
| Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats. | Neurotoxicology 20100301 |
| Ruthenium(II)-arene complexes with functionalized pyridines: synthesis, characterization and cytotoxic activity. | European journal of medicinal chemistry 20100301 |
| Adenoviral gene delivery of pigment epithelium-derived factor protects striatal neurons from quinolinic acid-induced excitotoxicity. | Journal of neuropathology and experimental neurology 20100301 |
| Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients. | Anaesthesia and intensive care 20100301 |
| Complete genomic sequence of bacteriophage felix o1. | Viruses 20100301 |
| Capillary electrophoresis for the monitoring of carboxylic acid production by Gluconobacter oxydans. | Journal of chromatography. A 20100226 |
| Roles for cationic residues at the quinolinic acid binding site of quinolinate phosphoribosyltransferase. | Biochemistry 20100223 |
| Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase. | Biochemistry 20100223 |
| NAD(P)H oxidase contributes to neurotoxicity in an excitotoxic/prooxidant model of Huntington's disease in rats: protective role of apocynin. | Journal of neuroscience research 20100215 |
| Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease. | Progress in neurobiology 20100209 |
| Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition. | Brain research 20100208 |
| Haemostatic system, biochemical profiles, kynurenines and the prevalence of cardiovascular disease in peritoneally dialyzed patients. | Thrombosis research 20100201 |
| Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model. | Experimental neurology 20100201 |
| Longitudinal MRI and MRSI characterization of the quinolinic acid rat model for excitotoxicity: peculiar apparent diffusion coefficients and recovery of N-acetyl aspartate levels. | NMR in biomedicine 20100201 |
| Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease. | Neurotoxicity research 20100101 |
| Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway. | Neuro-Signals 20100101 |
| Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine. | Journal of neural transmission (Vienna, Austria : 1996) 20100101 |
| Hyperfibrinolysis, uPA/suPAR system, kynurenines, and the prevalence of cardiovascular disease in patients with chronic renal failure on conservative treatment. | The American journal of the medical sciences 20100101 |
| Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons. | The FEBS journal 20100101 |
| Bioanalytical inaccuracy: a threat to the integrity and efficiency of research. | Journal of psychiatry & neuroscience : JPN 20100101 |
| COX-2 inhibitors as antidepressants and antipsychotics: clinical evidence. | Current opinion in investigational drugs (London, England : 2000) 20100101 |
| Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake. | PloS one 20100101 |
| Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage. | International journal of molecular sciences 20100101 |
| NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity. | BMC chemical biology 20100101 |
| Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease. | PloS one 20100101 |
| Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition. | Neurochemistry international 20100101 |
| Comparison of transplant efficiency between spontaneously derived and noggin-primed human embryonic stem cell neural precursors in the quinolinic acid rat model of Huntington's disease. | Cell transplantation 20100101 |
| Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders. | Genome medicine 20100101 |
| Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice. | Journal of translational medicine 20100101 |
| Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection. | Retrovirology 20100101 |
| Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms. | ASN neuro 20100101 |
| Pain perception in neurodevelopmental animal models of schizophrenia. | Physiological research 20100101 |
| Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression. | Malaria journal 20100101 |
| Systemic levels of MMP2/TIMP2 and cardiovascular risk in CAPD patients. | Nephron. Clinical practice 20100101 |
| Kynurenine pathway - a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients. | Advances in medical sciences 20100101 |
| Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication. | Behavioral and brain functions : BBF 20100101 |
| Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection. | AIDS research and therapy 20100101 |
| The Waddlia genome: a window into chlamydial biology. | PloS one 20100101 |
| The Ayurvedic drug, Ksheerabala, ameliorates quinolinic acid-induced oxidative stress in rat brain. | International journal of Ayurveda research 20100101 |
| Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention. | Behavioral and brain functions : BBF 20100101 |
| A novel anti-virulence gene revealed by proteomic analysis in Shigella flexneri 2a. | Proteome science 20100101 |
| Kynurenine and its metabolites in Alzheimer's disease patients. | Advances in medical sciences 20100101 |
| Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures. | Journal of neuroinflammation 20100101 |
| Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans. | PloS one 20100101 |
| Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease. | International journal of Alzheimer's disease 20100101 |
| Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. | Journal of nucleic acids 20100101 |
| Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus. | Molecular brain 20100101 |
| Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease. | BMC neuroscience 20100101 |
| Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease. | PloS one 20100101 |
| Viable mouse gene ablations that robustly alter brain Aβ levels are rare. | BMC neuroscience 20100101 |
| Inflammatory responses are not sufficient to cause delayed neuronal death in ATP-induced acute brain injury. | PloS one 20100101 |
| Nucleus Accumbens Core and Shell are Necessary for Reinforcer Devaluation Effects on Pavlovian Conditioned Responding. | Frontiers in integrative neuroscience 20100101 |
| A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. | BMC genomics 20100101 |
| Characterisation of the expression of NMDA receptors in human astrocytes. | PloS one 20100101 |
| Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide. | Journal of neuroinflammation 20100101 |
| Differential fate and functional outcome of lithium chloride primed adult neural progenitor cell transplants in a rat model of Huntington disease. | Stem cell research & therapy 20100101 |
| Contribution of CNS cells in NeuroAIDS. | Journal of pharmacy & bioallied sciences 20100101 |
| Molecular biology research in neuropsychiatry: India's contribution. | Indian journal of psychiatry 20100101 |
| Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as 'Glia Depressing Factor' (GDF). | International journal of tryptophan research : IJTR 20100101 |
| Editorial ISTRY Special Issue. | International journal of tryptophan research : IJTR 20100101 |
| On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio. | International journal of tryptophan research : IJTR 20100101 |
| Indoleamine 2,3-dioxygenase in human hematopoietic stem cell transplantation. | International journal of tryptophan research : IJTR 20100101 |
| Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. | International journal of tryptophan research : IJTR 20100101 |
| Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes. | International journal of tryptophan research : IJTR 20100101 |
| Understanding the roles of the kynurenine pathway in multiple sclerosis progression. | International journal of tryptophan research : IJTR 20100101 |
| Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid. | International journal of tryptophan research : IJTR 20100101 |
| Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection. | International journal of tryptophan research : IJTR 20100101 |
| Novel mechanisms of central nervous system damage in HIV infection. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase. | Biopolymers 20091201 |
| Delayed onset of the diurnal melatonin rise in patients with Huntington's disease. | Journal of neurology 20091201 |
| Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity. | Neurobiology of disease 20091201 |
| Profiles of the biosynthesis and metabolism of pyridine nucleotides in potatoes (Solanum tuberosum L.). | Planta 20091201 |
| Effects of caffeic acid, rofecoxib, and their combination against quinolinic acid-induced behavioral alterations and disruption in glutathione redox status. | Neuroscience bulletin 20091201 |
| Synaptotagmins in neurodegeneration. | Anatomical record (Hoboken, N.J. : 2007) 20091201 |
| p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms. | The European journal of neuroscience 20091201 |
| Effect of magnesium oxide on the activity of standard anti-epileptic drugs against experimental seizures in rats. | Indian journal of pharmacology 20091201 |
| Lactate is an alternative energy fuel to glucose in neurons under anesthesia. | Neuroreport 20091125 |
| [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20091101 |
| Effects of rodent prefrontal lesions on object-based, visual scene memory. | Neurobiology of learning and memory 20091101 |
| Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. | Journal of neural transmission (Vienna, Austria : 1996) 20091101 |
| Spermine improves recognition memory deficit in a rodent model of Huntington's disease. | Neurobiology of learning and memory 20091101 |
| Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. | Experimental hematology 20091101 |
| Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity. | Brain : a journal of neurology 20091101 |
| The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis. | The FEBS journal 20091101 |
| Slowed progression in models of Huntington disease by adipose stem cell transplantation. | Annals of neurology 20091101 |
| Neuroprotective effect of MK-801 against intra-striatal quinolinic acid induced behavioral, oxidative stress and cellular alterations in rats. | Indian journal of experimental biology 20091101 |
| Established therapies and novel targets in the treatment of Parkinson's disease. | Expert review of clinical pharmacology 20091101 |
| Thalidomide inhibition of vascular remodeling and inflammatory reactivity in the quinolinic acid-injected rat striatum. | Neuroscience 20091006 |
| Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy. | Amino acids 20091001 |
| Prefrontostriatal circuitry regulates effort-related decision making. | Cerebral cortex (New York, N.Y. : 1991) 20091001 |
| Acute intrastriatal administration of quinolinic acid affects the expression of the coat protein AP-2 and its interaction with membranes. | Journal of neural transmission (Vienna, Austria : 1996) 20091001 |
| [The transcription of the amyloid precursor protein and tryptophan 2,3-dioxygenase genes are increased by aging in the rat brain]. | Ideggyogyaszati szemle 20090930 |
| Effects of lesions of the nucleus accumbens core on inter-temporal choice: further observations with an adjusting-delay procedure. | Behavioural brain research 20090914 |
| Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310. | The Journal of organic chemistry 20090904 |
| Kynurenines and oxidative status are independently associated with thrombomodulin and von Willebrand factor levels in patients with end-stage renal disease. | Thrombosis research 20090901 |
| Constructing mixed-metal coordination polymers from copper(II)-pyridinedicarboxylate metalloligands. | Acta crystallographica. Section C, Crystal structure communications 20090901 |
| Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. | Dialogues in clinical neuroscience 20090901 |
| The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment. | Dialogues in clinical neuroscience 20090901 |
| The neurotrophic and neuroprotective effects of psychotropic agents. | Dialogues in clinical neuroscience 20090901 |
| Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity. | Current neuropharmacology 20090901 |
| Poly[[diaqua-(ethanol)bis-(μ(3)-pyridine-2,3-dicarboxyl-ato)dimanganese(II)] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20090901 |
| The anterior cingulate cortex is involved in retrieval of long-term/long-lasting but not short-term memory for step-through inhibitory avoidance in rats. | Neuroscience letters 20090828 |
| The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection. | Journal of the neurological sciences 20090815 |
| In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents. | Neurochemical research 20090801 |
| Effects of kynurenine metabolites on mesangial cell proliferation and gene expression. | Experimental and molecular pathology 20090801 |
| Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake. | Neurotoxicity research 20090801 |
| Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. | Nature chemical biology 20090801 |
| Early nerve ending rescue from oxidative damage and energy failure by L: -carnitine as post-treatment in two neurotoxic models in rat: recovery of antioxidant and reductive capacities. | Experimental brain research 20090801 |
| Effect of caffeic acid and rofecoxib and their combination against intrastriatal quinolinic acid induced oxidative damage, mitochondrial and histological alterations in rats. | Inflammopharmacology 20090801 |
| Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a nonspatial decision-making maze task. | The European journal of neuroscience 20090801 |
| Benzyl-chloridobis(quinolin-8-olato)tin(IV). | Acta crystallographica. Section E, Structure reports online 20090801 |
| Impact of co administration of selenium and quinolinic acid in the rat's brain. | Brain research 20090724 |
| New evidence on hypoglycemic effect of quinolinic acid in diabetic rats. | Pakistan journal of biological sciences : PJBS 20090715 |
| Convergent, not serial, striatal and pallidal circuits regulate opioid-induced food intake. | Neuroscience 20090707 |
| Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons. | Neurotoxicity research 20090701 |
| Kynurenine, quinolinic acid--the new factors linked to carotid atherosclerosis in patients with end-stage renal disease. | Atherosclerosis 20090601 |
| Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601 |
| Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease. | Neurobiology of disease 20090601 |
| Chemokines direct neural progenitor cell migration following striatal cell loss. | Molecular and cellular neurosciences 20090601 |
| Activin A is essential for neurogenesis following neurodegeneration. | Stem cells (Dayton, Ohio) 20090601 |
| Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen. | PLoS pathogens 20090601 |
| Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease. | Behavioural brain research 20090516 |
| Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease. | Journal of neuroscience methods 20090515 |
| Structural and photophysical studies of highly stable lanthanide complexes of tripodal 8-hydroxyquinolinate ligands based on 1,4,7-triazacyclononane. | Inorganic chemistry 20090504 |
| Simultaneous two-voxel localized (1)H-observed (13)C-edited spectroscopy for in vivo MRS on rat brain at 9.4T: Application to the investigation of excitotoxic lesions. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20090501 |
| Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. | Brain : a journal of neurology 20090501 |
| Metallothionein treatment attenuates microglial activation and expression of neurotoxic quinolinic acid following traumatic brain injury. | Neurotoxicity research 20090501 |
| Differential expression of activating transcription factor-2 and c-Jun in the immature and adult rat hippocampus following lithium-pilocarpine induced status epilepticus. | Yonsei medical journal 20090430 |
| Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats. | European journal of nutrition 20090401 |
| On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. | Journal of neurochemistry 20090401 |
| [Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20090401 |
| Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum. | Neuroscience 20090303 |
| Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid. | Journal of neurochemistry 20090301 |
| Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior. | Journal of immunology (Baltimore, Md. : 1950) 20090301 |
| Graft outcomes influenced by co-expression of Pax7 in graft and host tissue. | Journal of anatomy 20090301 |
| Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease. | The European journal of neuroscience 20090301 |
| Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. | PLoS pathogens 20090301 |
| Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors. | Central nervous system agents in medicinal chemistry 20090301 |
| Tetra-aqua-(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)nickel(II) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)nickel(II) trihydrate. | Acta crystallographica. Section E, Structure reports online 20090301 |
| Bis(3,5-dimethyl-1H-pyrazole-κN)(pyridine-2,6-dicarboxyl-ato-κO,N,O)copper(II). | Acta crystallographica. Section E, Structure reports online 20090301 |
| catena-Poly[[(pyridine-κN)copper(II)]-μ(3)-pyridine-2,6-dicarboxylato-κO:O,N,O:O]. | Acta crystallographica. Section E, Structure reports online 20090301 |
| Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090218 |
| Pre-surgical training ameliorates orbitofrontal-mediated impairments in spatial reversal learning. | Behavioural brain research 20090211 |
| Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. | Diabetes 20090201 |
| Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. | International journal for parasitology 20090201 |
| NAD biosynthesis evolution in bacteria: lateral gene transfer of kynurenine pathway in Xanthomonadales and Flavobacteriales. | Molecular biology and evolution 20090201 |
| The natural xanthone alpha-mangostin reduces oxidative damage in rat brain tissue. | Nutritional neuroscience 20090201 |
| Prolonged survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions. | Medical science monitor : international medical journal of experimental and clinical research 20090201 |
| Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity. | Journal of medicinal chemistry 20090122 |
| Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride. | Psychopharmacology 20090101 |
| Anti-infectious activity of tryptophan metabolites in the L-tryptophan-L-kynurenine pathway. | Biological & pharmaceutical bulletin 20090101 |
| A trouble shared is a trouble halved: social context and status affect pain in mouse dyads. | PloS one 20090101 |
| Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. | BMC gastroenterology 20090101 |
| Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. | International journal of biological sciences 20090101 |
| Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders. | CNS drugs 20090101 |
| Normal aging modulates the neurotoxicity of mutant huntingtin. | PloS one 20090101 |
| New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6. | Trials 20090101 |
| Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress. | Journal of neuroinflammation 20090101 |
| QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant; a gene expression, RNA and immunohistochemical study. | BMC cancer 20090101 |
| Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons. | PloS one 20090101 |
| Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis. | PPAR research 20090101 |
| The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens. | BMC microbiology 20090101 |
| Genetic characterization of type A enterotoxigenic Clostridium perfringens strains. | PloS one 20090101 |
| Activin signaling as an emerging target for therapeutic interventions. | Cell communication and signaling : CCS 20090101 |
| The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. | PloS one 20090101 |
| NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. | Journal of neuroinflammation 20090101 |
| [Tryptophan and its metabolites in renal allograft recipients]. | Przeglad lekarski 20090101 |
| The formin-homology protein SmDia interacts with the Src kinase SmTK and the GTPase SmRho1 in the gonads of Schistosoma mansoni. | PloS one 20090101 |
| Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats. | PloS one 20090101 |
| Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth. | PloS one 20090101 |
| Status epilepticus affects the gigantocellular network of the pontine reticular formation. | BMC neuroscience 20090101 |
| Breaching the blood-brain barrier as a gate to psychiatric disorder. | Cardiovascular psychiatry and neurology 20090101 |
| Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease. | Journal of neuroinflammation 20090101 |
| Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum. | Oxidative medicine and cellular longevity 20090101 |
| Aqua-(1,10-phenanthroline)(pyridine-2,6-dicarboxyl-ato)nickel(II) pyridine-2,6-di-carboxylic acid solvate tetra-hydrate. | Acta crystallographica. Section E, Structure reports online 20090101 |
| 4,4'-Bipyridinium bis-(2-carboxy-pyridine-3-carboxyl-ate). | Acta crystallographica. Section E, Structure reports online 20090101 |
| Kynurenine pathway metabolites in humans: disease and healthy States. | International journal of tryptophan research : IJTR 20090101 |
| Paolo guidetti. | International journal of tryptophan research : IJTR 20090101 |
| Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model. | International journal of tryptophan research : IJTR 20090101 |
| Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons. | International journal of tryptophan research : IJTR 20090101 |
| The physiological action of picolinic Acid in the human brain. | International journal of tryptophan research : IJTR 20090101 |
| Effect of quinolinic acid-induced lesions of the subthalamic nucleus on performance on a progressive-ratio schedule of reinforcement: a quantitative analysis. | Behavioural brain research 20081222 |
| Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease. | Neuroscience letters 20081219 |
| Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation. | The Journal of organic chemistry 20081205 |
| Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation. | European journal of nuclear medicine and molecular imaging 20081201 |
| Microanatomical evidences for potential of mesenchymal stem cells in amelioration of striatal degeneration. | Neurological research 20081201 |
| Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures. | Phytochemistry 20081201 |
| Exploring the mechanism of tryptophan 2,3-dioxygenase. | Biochemical Society transactions 20081201 |
| Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation. | PLoS neglected tropical diseases 20081201 |
| catena-Poly[[[aqua-(1,10-phenanthroline-κN,N')cadmium(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O,O] dihydrate]. | Acta crystallographica. Section E, Structure reports online 20081201 |
| Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases. | Journal of medicinal chemistry 20081127 |
| Polyfunctional recognition of pyridinedicarboxylate anions with macrocyclic polyamine receptors containing heteroaromatic groups. | The Journal of organic chemistry 20081107 |
| Synthesis, characterization and fluorescence properties of novel pyridine dicarboxylic acid derivatives and corresponding Tb(III) complexes. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081101 |
| Role of the striatum in the humoral immune response to thymus-independent and thymus-dependent antigens in rats. | Immunology letters 20081030 |
| Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20081022 |
| Characterization of quinolinate synthases from Escherichia coli, Mycobacterium tuberculosis, and Pyrococcus horikoshii indicates that [4Fe-4S] clusters are common cofactors throughout this class of enzymes. | Biochemistry 20081014 |
| Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging. | Stem cells (Dayton, Ohio) 20081001 |
| Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2. | Journal of neurochemistry 20081001 |
| Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status. | Psychiatry and clinical neurosciences 20081001 |
| Characterization of L-aspartate oxidase and quinolinate synthase from Bacillus subtilis. | The FEBS journal 20081001 |
| The Arabidopsis onset of leaf death5 mutation of quinolinate synthase affects nicotinamide adenine dinucleotide biosynthesis and causes early ageing. | The Plant cell 20081001 |
| catena-Poly[[[triaqua-copper(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O] monohydrate]. | Acta crystallographica. Section E, Structure reports online 20081001 |
| catena-Poly[[[diaqua-manganese(II)]-μ(3)-pyridine-2,3-dicarboxyl-ato-κN,O:O:O] dihydrate]. | Acta crystallographica. Section E, Structure reports online 20081001 |
| catena-Poly[[[aqua-cadmium(II)]bis-(μ-4-hydroxy-pyridine-2,6-dicarboxyl-ato)[aqua-cadmium(II)]di-μ-aqua] tetra-hydrate]. | Acta crystallographica. Section E, Structure reports online 20081001 |
| Binding synergy and cooperativity in dihydrodipicolinate reductase: implications for mechanism and the design of biligand inhibitors. | Biochemistry 20080923 |
| Intact intracortical microstimulation (ICMS) representations of rostral and caudal forelimb areas in rats with quinolinic acid lesions of the medial or lateral caudate-putamen in an animal model of Huntington's disease. | Brain research bulletin 20080905 |
| A functional dissociation of the anterior and posterior pedunculopontine tegmental nucleus: excitotoxic lesions have differential effects on locomotion and the response to nicotine. | Brain structure & function 20080901 |
| Quinolinate-induced rat striatal excitotoxicity impairs endoplasmic reticulum Ca2+-ATPase function. | Neurochemical research 20080901 |
| The basal ganglia and cerebellum interact in the expression of dystonic movement. | Brain : a journal of neurology 20080901 |
| Neurogenesis in the chronic lesions of multiple sclerosis. | Brain : a journal of neurology 20080901 |
| Melatonin combats molecular terrorism at the mitochondrial level. | Interdisciplinary toxicology 20080901 |
| Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis. | Behavioural brain research 20080822 |
| The [4Fe-4S] cluster of quinolinate synthase from Escherichia coli: investigation of cluster ligands. | FEBS letters 20080820 |
| Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation. | Biochemistry 20080819 |
| Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum. | Stem cells (Dayton, Ohio) 20080801 |
| Gravity-flow open tubular cation chromatography. | Journal of separation science 20080801 |
| AAV-BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment. | Gene therapy 20080701 |
| Measurement of the (14)N nuclear quadrupole resonance frequencies by the solid effect. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20080701 |
| Somatostatin in medium-sized aspiny interneurons of striatum is responsible for their preservation in quinolinic acid and N-methyl-D-asparate-induced neurotoxicity. | Journal of molecular neuroscience : MN 20080701 |
| Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan. | Bioscience, biotechnology, and biochemistry 20080701 |
| Contrasting effects of selective lesions of nucleus accumbens core or shell on inhibitory control and amphetamine-induced impulsive behaviour. | The European journal of neuroscience 20080701 |
| Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. | Brain research 20080618 |
| Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease. | Neurobiology of disease 20080601 |
| A psychoneuroimmunological perspective to Emil Kraepelins dichotomy: schizophrenia and major depression as inflammatory CNS disorders. | European archives of psychiatry and clinical neuroscience 20080601 |
| Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro. | Journal of medicinal food 20080601 |
| AAV-mediated expression of Bcl-xL or XIAP fails to induce neuronal resistance against quinolinic acid-induced striatal lesioning. | Neuroscience letters 20080516 |
| An organotellurium compound with antioxidant activity against excitotoxic agents without neurotoxic effects in brain of rats. | Brain research bulletin 20080515 |
| Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate. | Journal of agricultural and food chemistry 20080514 |
| Expression profiles of the organic acid metabolism-associated genes during rat liver regeneration. | Amino acids 20080501 |
| Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine. | Journal of neurochemistry 20080501 |
| Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity. | Journal of neurochemistry 20080501 |
| Neurotoxic lesions of the medial prefrontal cortex or medial striatum impair multiple-location place learning in the water task: evidence for neural structures with complementary roles in behavioural flexibility. | Experimental brain research 20080501 |
| Expression of amphetamine sensitization is associated with recruitment of a reactive neuronal population in the nucleus accumbens core. | Psychopharmacology 20080501 |
| DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080501 |
| A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. | Stress (Amsterdam, Netherlands) 20080501 |
| Suppression of activity in the forelimb motor cortex temporarily enlarges forelimb representation in the homotopic cortex in adult rats. | The European journal of neuroscience 20080501 |
| Quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation. | European journal of nuclear medicine and molecular imaging 20080401 |
| Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: implications for inter-temporal choice. | Psychopharmacology 20080401 |
| Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. | The Journal of allergy and clinical immunology 20080401 |
| Effect of PK11195 on attenuating the enhancement of glucose utilization induced by quinolinic acid infusion in the rat brain. | Synapse (New York, N.Y.) 20080401 |
| Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury. | Molecular and cellular neurosciences 20080401 |
| Excitotoxic neuronal death and the pathogenesis of Huntington's disease. | Archives of medical research 20080401 |
| Comprehensive X-ray structural studies of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae. | Biochemistry 20080401 |
| Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions. | Neuroscience 20080327 |
| Spermine attenuates behavioral and biochemical alterations induced by quinolinic acid in the striatum of rats. | Brain research 20080310 |
| Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid. | Neurobiology of disease 20080301 |
| Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques. | Psychopharmacology 20080301 |
| Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling. | Neurobiology of disease 20080301 |
| Cytoplasmic calcium mediates oxidative damage in an excitotoxic /energetic deficit synergic model in rats. | The European journal of neuroscience 20080301 |
| Pharmacodynamics of memantine: an update. | Current neuropharmacology 20080301 |
| Hepatic alteration of tryptophan metabolism in an acute porphyria model Its relation with gluconeogenic blockage. | Biochemical pharmacology 20080201 |
| Neurotoxic damage to the dorsomedial striatum exaggerates the behavioral influence of a context-specific inhibitory association mediated by the ventral hippocampus. | Behavioral neuroscience 20080201 |
| Poly[propane-1,3-diammonium [cuprate(II)-bis-(μ(2)-pyridine-2,3-dicarboxyl-ato)] trihydrate]. | Acta crystallographica. Section E, Structure reports online 20080201 |
| catena-Poly[[triaqua-cadmium(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O]. | Acta crystallographica. Section E, Structure reports online 20080201 |
| catena-Poly[[[diaqua-iron(II)]-μ-pyridine-2,5-dicarboxyl-ato-[tetra-aqua-iron(II)]-μ-pyridine-2,5-dicarboxyl-ato] tetra-hydrate]. | Acta crystallographica. Section E, Structure reports online 20080201 |
| Behavioural and neurochemical characterization of the adenosine A2A receptor antagonist ST1535. | European journal of pharmacology 20080128 |
| Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys. | Behavioural brain research 20080125 |
| Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines. | Neurochemical research 20080101 |
| The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders. | Medical hypotheses 20080101 |
| Microglial activation, macrophage infiltration, and evidence of cell death in the fetal brain after uteroplacental administration of lipopolysaccharide in sheep in late gestation. | American journal of obstetrics and gynecology 20080101 |
| Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model. | Arthritis research & therapy 20080101 |
| Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice. | Epilepsia 20080101 |
| Human embryonic stem cells: preclinical perspectives. | Journal of translational medicine 20080101 |
| Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease. | Journal of neuroinflammation 20080101 |
| Investigation of Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) Porphyrazine for Application as Photosensitizer in Photodynamic Therapy of Cancer. | Metal-based drugs 20080101 |
| Transplants of encapsulated rat choroid plexus cells exert neuroprotection in a rodent model of Huntington's disease. | Cell transplantation 20080101 |
| Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia. | Journal of neuroinflammation 20080101 |
| Pillaring of CdCl2-like layers in lanthanide metal-organic frameworks: synthesis, structure, and photophysical properties. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult. | Journal of neuroinflammation 20080101 |
| Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells. | International journal of medical sciences 20080101 |
| Iron porphyrinate Fe(TPPS) reduces brain cell damage in rats intrastriatally lesioned by quinolinate. | Neurotoxicology and teratology 20080101 |
| Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. | Journal of neuroinflammation 20080101 |
| Potential developmental neurotoxicity of pesticides used in Europe. | Environmental health : a global access science source 20080101 |
| Excitation Control: Balancing PSD-95 Function at the Synapse. | Frontiers in molecular neuroscience 20080101 |
| A possible central mechanism in autism spectrum disorders, part 1. | Alternative therapies in health and medicine 20080101 |
| Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder. | BMC medical genetics 20080101 |
| A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review. | The open dentistry journal 20080101 |
| HIV-1 Antigens in Neurons of Cocaine-Abusing Patients. | The open virology journal 20080101 |
| Psychological factors in asthma. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101 |
| Piperazinediium bis-(2-carboxy-pyridine-3-carboxyl-ate). | Acta crystallographica. Section E, Structure reports online 20080101 |
| Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus. | Brain research 20071212 |
| Citicoline is not protective in experimental models of Huntington's disease. | Neurobiology of aging 20071201 |
| IDO expression in the brain: a double-edged sword. | Journal of molecular medicine (Berlin, Germany) 20071201 |
| Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201 |
| N-methyl-D-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus. | Journal of neuroscience research 20071201 |
| Tryptophan, adenosine, neurodegeneration and neuroprotection. | Metabolic brain disease 20071201 |
| The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. | Neuro endocrinology letters 20071201 |
| 4-pyridone-3-carboxamide ribonucleoside triphosphate accumulating in erythrocytes in end stage renal failure originates from tryptophan metabolism. | Clinical and experimental medicine 20071201 |
| The involvement of astrocytes and kynurenine pathway in Alzheimer's disease. | Neurotoxicity research 20071201 |
| Cannabinoids in health and disease. | Dialogues in clinical neuroscience 20071201 |
| A series of lanthanide-transition metal frameworks based on 1-, 2-, and 3D metal-organic motifs linked by different 1D copper(I) halide motifs. | Inorganic chemistry 20071126 |
| The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. | Molecular psychiatry 20071101 |
| Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis. | Psychopharmacology 20071101 |
| Time-related changes in constitutive and inducible nitric oxide synthases in the rat striatum in a model of Huntington's disease. | Neurotoxicology 20071101 |
| IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cells. | European journal of immunology 20071101 |
| Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. | Journal of molecular biology 20071026 |
| Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071001 |
| IFN-gamma-induced IDO and WRS expression in microglia is differentially regulated by IL-4. | Glia 20071001 |
| Inflammation, depression and dementia: are they connected? | Neurochemical research 20071001 |
| The role of Phe181 in the hexamerization of Helicobacter pylori quinolinate phosphoribosyltransferase. | The protein journal 20071001 |
| Altered kynurenine metabolism correlates with infarct volume in stroke. | The European journal of neuroscience 20071001 |
| Distinct contributions of frontal areas to emotion and social behaviour in the rat. | The European journal of neuroscience 20071001 |
| Central tegmental field and sexual behavior in the male rat: effects of neurotoxic lesions. | Neuroscience 20070921 |
| Poly(ADP-ribose) polymerase-1 is involved in the neuronal death induced by quinolinic acid in rats. | Neuroscience letters 20070920 |
| A comparison between the determination of free Pb(II) by two techniques: absence of gradients and Nernstian equilibrium stripping and resin titration. | Analytica chimica acta 20070905 |
| L-NAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases. | Journal of neuroscience research 20070901 |
| The anti-allergic drug, N-(3',4'-dimethoxycinnamonyl) anthranilic acid, exhibits potent anti-inflammatory and analgesic properties in arthritis. | Rheumatology (Oxford, England) 20070901 |
| Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease. | Purinergic signalling 20070901 |
| Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity. | Neuroscience 20070810 |
| Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions. | Neuroscience letters 20070809 |
| Involvement of P-glycoprotein and multidrug resistance associated protein 1 in the transport of tanshinone IIB, a primary active diterpenoid quinone from the roots of Salvia miltiorrhiza, across the blood-brain barrier. | Drug metabolism letters 20070801 |
| An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions. | Journal of neuroscience methods 20070730 |
| Changes in neuronal protein expression in LP-BM5-infected mice. | Neuroscience letters 20070711 |
| The role of the agranular insular cortex in anticipation of reward contrast. | Neurobiology of learning and memory 20070701 |
| nadA and nadB of Shigella flexneri 5a are antivirulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity. | Microbiology (Reading, England) 20070701 |
| Different transfer of nociceptive sensitivity from rats with postnatal hippocampal lesions to control rats. | The European journal of neuroscience 20070701 |
| Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701 |
| Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. | Biochemistry 20070626 |
| Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders. | Journal of the neurological sciences 20070615 |
| Temporal profile of subventricular zone progenitor cell migration following quinolinic acid-induced striatal cell loss. | Neuroscience 20070608 |
| Effect of prefrontal cortex inactivation on behavioral and neurochemical abnormalities in rats with excitotoxic lesions of the entorhinal cortex. | Synapse (New York, N.Y.) 20070601 |
| AAV-mediated delivery of BDNF augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain. | The European journal of neuroscience 20070601 |
| Plastic changes in the vibrissa motor cortex in adult rats after output suppression in the homotopic cortex. | The European journal of neuroscience 20070601 |
| Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier. | Xenobiotica; the fate of foreign compounds in biological systems 20070601 |
| Neuropsychiatric manifestations of depression in multiple sclerosis: neuroinflammatory, neuroendocrine, and neurotrophic mechanisms in the pathogenesis of immune-mediated depression. | Dialogues in clinical neuroscience 20070601 |
| Nuclear factor-kappaB-dependent cyclin D1 induction and DNA replication associated with N-methyl-D-aspartate receptor-mediated apoptosis in rat striatum. | Journal of neuroscience research 20070501 |
| Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration. | Journal of neuropathology and experimental neurology 20070501 |
| Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier. | Current drug metabolism 20070501 |
| Neurotoxic lesions of the caudate-putamen on a reaching for food task in the rat: acute sensorimotor neglect and chronic qualitative motor impairment follow lateral lesions and improved success follows medial lesions. | Neuroscience 20070425 |
| Dopamine efflux in the nucleus accumbens during within-session extinction, outcome-dependent, and habit-based instrumental responding for food reward. | Psychopharmacology 20070401 |
| Interleukin-1beta but not tumor necrosis factor-alpha potentiates neuronal damage by quinolinic acid: protection by an adenosine A2A receptor antagonist. | Journal of neuroscience research 20070401 |
| Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK. | Molecular microbiology 20070401 |
| Non-steroidal anti-inflammatory agents, tolmetin and sulindac attenuate quinolinic acid (QA)-induced oxidative stress in primary hippocampal neurons and reduce QA-induced spatial reference memory deficits in male Wistar rats. | Life sciences 20070320 |
| Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion. | Neuroscience 20070316 |
| Investigation of the antioxidant activity of African potato (Hypoxis hemerocallidea). | Journal of agricultural and food chemistry 20070307 |
| Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease. | Experimental brain research 20070301 |
| Depletion of neutrophils reduces neuronal degeneration and inflammatory responses induced by quinolinic acid in vivo. | Glia 20070301 |
| Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy. | Journal of neurochemistry 20070301 |
| Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications. | Journal of neuroscience research 20070301 |
| Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial. | PLoS clinical trials 20070301 |
| Dietary protein level and dietary interaction affect quinolinic acid concentration in rats. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070301 |
| Potential of adult neural stem cells for cellular therapy. | Biologics : targets & therapy 20070301 |
| Determination of kynurenine levels in rat plasma by high-performance liquid chromatography with pre-column fluorescence derivatization. | Analytica chimica acta 20070219 |
| Mechanisms by which acyclovir reduces the oxidative neurotoxicity and biosynthesis of quinolinic acid. | Life sciences 20070213 |
| Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats. | Neuroscience 20070209 |
| Heterologous expression and purification of kynurenine-3-monooxygenase from Pseudomonas fluorescens strain 17400. | Protein expression and purification 20070201 |
| In vitro effect of quinolinic acid on energy metabolism in brain of young rats. | Neuroscience research 20070201 |
| Beneficial effects of rolipram in a quinolinic acid model of striatal excitotoxicity. | Neurobiology of disease 20070201 |
| Excess dietary lysine increases growth of chicks fed niacin-deficient diets, but dietary quinolinic acid has no niacin-sparing activity. | Poultry science 20070201 |
| Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism. | The FEBS journal 20070201 |
| Adenosine A2A receptor blockade before striatal excitotoxic lesions prevents long term behavioural disturbances in the quinolinic rat model of Huntington's disease. | Behavioural brain research 20070125 |
| Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. | Neuroscience 20070119 |
| Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis. | Biochemistry 20070109 |
| Integrative hypothesis for Huntington's disease: a brief review of experimental evidence. | Physiological research 20070101 |
| Proteasome activator enhances survival of Huntington's disease neuronal model cells. | PloS one 20070101 |
| Mechanisms of copper ion mediated Huntington's disease progression. | PloS one 20070101 |
| Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli. | BMC bioinformatics 20070101 |
| Stem cell therapy for autism. | Journal of translational medicine 20070101 |
| Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat. | Journal of neuroinflammation 20070101 |
| Animal models of Huntington's disease. | ILAR journal 20070101 |
| Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase. | BMC structural biology 20070101 |
| Aging reduces the neuroprotective capacity, VEGF secretion, and metabolic activity of rat choroid plexus epithelial cells. | Cell transplantation 20070101 |
| Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. | BMC genomics 20070101 |
| Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains. | The European journal of neuroscience 20061201 |
| Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise. | The European journal of neuroscience 20061201 |
| Evidence that quinolinic acid severely impairs energy metabolism through activation of NMDA receptors in striatum from developing rats. | Journal of neurochemistry 20061201 |
| Therapeutic Strategies in Huntington's Disease. | Journal of clinical neurology (Seoul, Korea) 20061201 |
| Sensitive femtosecond coherent anti-Stokes Raman spectroscopy discrimination between dipicolinic acid and dinicotinic acid. | Optics letters 20061101 |
| Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment. | Clinical and experimental pharmacology & physiology 20061101 |
| Is the functional interaction between adenosine A(2A) receptors and metabotropic glutamate 5 receptors a general mechanism in the brain? Differences and similarities between the striatum and the hippocampus. | Purinergic signalling 20061101 |
| Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease. | Neuroreport 20061023 |
| Synthesis, structure and fluorescent studies of novel uranium coordination polymers in the pyridinedicarboxylic acid system. | Dalton transactions (Cambridge, England : 2003) 20061021 |
| Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. | Behavioural brain research 20061016 |
| The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum. | Neuropharmacology 20061001 |
| Inflammation and depression: is there a causal connection with dementia? | Neurotoxicity research 20061001 |
| Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains. | The European journal of neuroscience 20061001 |
| Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease. | Neuroscience 20060915 |
| Crystal structure of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase: insight into the active site and catalytic mechanism of a novel decarboxylation reaction. | Biochemistry 20060905 |
| Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons. | Metabolic brain disease 20060901 |
| Acetylsalicylic acid and acetaminophen protect against oxidative neurotoxicity. | Metabolic brain disease 20060901 |
| Interferon-induced depressive illness in hep C patients responds to SSRI antidepressant treatments. | Neuropsychiatric disease and treatment 20060901 |
| Tryptophan metabolism in the central nervous system: medical implications. | Expert reviews in molecular medicine 20060831 |
| Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro. | Brain research 20060830 |
| A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060801 |
| Time course of oxidative events in the hippocampus following intracerebroventricular infusion of quinolinic acid in mice. | Neuroscience research 20060801 |
| Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys. | Neurobiology of disease 20060801 |
| Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice. | Neurobiology of disease 20060701 |
| Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid. | Plant physiology 20060701 |
| Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO. | Journal of immunology (Baltimore, Md. : 1950) 20060701 |
| Protective effects of PACAP in excitotoxic striatal lesion. | Annals of the New York Academy of Sciences 20060701 |
| The role of the dorsolateral tegmentum in the control of male sexual behavior: a reevaluation. | Behavioural brain research 20060630 |
| Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. | Cell 20060616 |
| The effects of lateralized training on spontaneous forelimb preference, lesion deficits, and graft-mediated functional recovery after unilateral striatal lesions in rats. | Experimental neurology 20060601 |
| Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease. | Experimental neurology 20060601 |
| Quinolinic acid modulates the activity of src family kinases in rat striatum: in vivo and in vitro studies. | Journal of neurochemistry 20060601 |
| 4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury. | Journal of neurotrauma 20060601 |
| Is the L-tryptophan metabolite quinolinic acid responsible for eosinophilic fasciitis? | Clinical and experimental medicine 20060601 |
| Changes in the immune system in depression and dementia: causal or coincidental effects? | Dialogues in clinical neuroscience 20060601 |
| Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060531 |
| Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Immunopathogenesis of cerebral malaria. | International journal for parasitology 20060501 |
| Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease. | Journal of neuroscience methods 20060415 |
| Normal sensitivity to excitotoxicity in a transgenic Huntington's disease rat. | Brain research bulletin 20060414 |
| Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Saccharomyces cerevisiae: a special subgroup of the type III extradiol dioxygenases. | Protein science : a publication of the Protein Society 20060401 |
| Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes. | Journal of leukocyte biology 20060301 |
| Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla. | Journal of neuroscience research 20060301 |
| Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine receptor blockade in rats. | Brain research 20060216 |
| Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion. | Experimental neurology 20060201 |
| Wild-type huntingtin protects neurons from excitotoxicity. | Journal of neurochemistry 20060201 |
| Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs. | Brain research 20060119 |
| Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease. | Experimental neurology 20060101 |
| Tryptophan metabolism and oxidative stress in patients with chronic brain injury. | European journal of neurology 20060101 |
| Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease. | The European journal of neuroscience 20060101 |
| Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation. | Journal of neuroinflammation 20060101 |
| Melatonin in Alzheimer's disease and other neurodegenerative disorders. | Behavioral and brain functions : BBF 20060101 |
| HIV-1 associated dementia: symptoms and causes. | Retrovirology 20060101 |
| NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions. | Journal of experimental botany 20060101 |
| Gene expression in cortex and hippocampus during acute pneumococcal meningitis. | BMC biology 20060101 |
| Glutamate receptors in neuroinflammatory demyelinating disease. | Mediators of inflammation 20060101 |
| Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway. | BMC genomics 20060101 |
| Kynurenines, Parkinson's disease and other neurodegenerative disorders: preclinical and clinical studies. | Journal of neural transmission. Supplementum 20060101 |
| Human malarial disease: a consequence of inflammatory cytokine release. | Malaria journal 20060101 |
| HIV neurotoxicity: potential therapeutic interventions. | Journal of biomedicine & biotechnology 20060101 |
| Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease. | BMC neuroscience 20060101 |
| In vitro culture duration does not impact the ability of encapsulated choroid plexus transplants to prevent neurological deficits in an excitotoxin-lesioned rat model of Huntington's disease. | Cell transplantation 20060101 |
| Selenium reduces the proapoptotic signaling associated to NF-kappaB pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by quinolinate in rat corpus striatum. | Synapse (New York, N.Y.) 20051215 |
| Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy. | Brain research bulletin 20051215 |
| Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism. | Biochemical and biophysical research communications 20051209 |
| Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20051201 |
| Long-term functional consequences of quinolinic acid striatal lesions and their alteration following an addition of a globus pallidus lesion assessed using pharmacological magnetic resonance imaging. | Experimental neurology 20051201 |
| Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage. | Journal of neuroscience research 20051201 |
| Deprenyl enhances the striatal neuronal damage produced by quinolinic acid. | Brain research. Molecular brain research 20051118 |
| Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum. | Neurobiology of disease 20051101 |
| Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity. | Neurobiology of disease 20051101 |
| Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. | American journal of physiology. Cell physiology 20051101 |
| Neuronal localization of indoleamine 2,3-dioxygenase in mice. | Neuroscience letters 20051021 |
| Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. | Blood 20051001 |
| Melatonin neutralizes neurotoxicity induced by quinolinic acid in brain tissue culture. | Journal of pineal research 20051001 |
| The uncoupling agent 2,4-dinitrophenol improves mitochondrial homeostasis following striatal quinolinic acid injections. | Journal of neurotrauma 20051001 |
| [Animal models of parkinsonism]. | Revue neurologique 20051001 |
| Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury. | Experimental neurology 20050901 |
| Cerebrospinal fluid and serum markers of inflammation in autism. | Pediatric neurology 20050901 |
| Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro. | Cellular and molecular neurobiology 20050901 |
| Riluzole improves motor deficits and attenuates loss of striatal neurons in a sequential double lesion rat model of striatonigral degeneration (parkinson variant of multiple system atrophy). | Journal of neural transmission (Vienna, Austria : 1996) 20050801 |
| Kynurenine metabolism in multiple sclerosis. | Acta neurologica Scandinavica 20050801 |
| Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus. | Neuropathology and applied neurobiology 20050801 |
| Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation. | Neuroreport 20050801 |
| Pig xenografts to the immunocompetent rat brain: Survival rates using distinct neurotoxic lesions in the nigrostriatal pathway and two rat strains. | Experimental neurology 20050801 |
| The nadA gene of Pseudomonas fluorescens PGPR strain 267.1. | Current microbiology 20050801 |
| Three-dimensional 3d-4f heterometallic coordination polymers: synthesis, structures, and magnetic properties. | Inorganic chemistry 20050725 |
| Analysis of the heteromeric CsdA-CsdE cysteine desulfurase, assisting Fe-S cluster biogenesis in Escherichia coli. | The Journal of biological chemistry 20050722 |
| Crystal structure of the NAD biosynthetic enzyme quinolinate synthase. | The Journal of biological chemistry 20050722 |
| Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis. | FEBS letters 20050704 |
| Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model. | Neuroscience research 20050701 |
| Glucocorticoid enhances the neurotoxic actions of quinolinic acid in the striatum in a cell-specific manner. | Journal of neuroendocrinology 20050701 |
| Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. | Movement disorders : official journal of the Movement Disorder Society 20050701 |
| 6-Hydroxymelatonin protects against quinolinic-acid-induced oxidative neurotoxicity in the rat hippocampus. | The Journal of pharmacy and pharmacology 20050701 |
| Aciclovir protects against quinolinic-acid-induced oxidative neurotoxicity. | The Journal of pharmacy and pharmacology 20050701 |
| Role of kynurenines in the central and peripheral nervous systems. | Current neurovascular research 20050701 |
| Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype. | Biochimica et biophysica acta 20050620 |
| Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds. | Journal of experimental botany 20050601 |
| The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050601 |
| Cytokine regulation of tryptophan metabolism in the hypothalamic-pituitary-adrenal (HPA) axis: implications for protective and toxic consequences in neuroendocrine regulation. | Cellular and molecular neurobiology 20050601 |
| Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade. | Purinergic signalling 20050601 |
| The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. | Biochemistry 20050531 |
| Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis. | Biochemistry 20050531 |
| Escherichia coli quinolinate synthetase does indeed harbor a [4Fe-4S] cluster. | Journal of the American Chemical Society 20050525 |
| In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking. | Brain research 20050510 |
| Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum. | The Journal of biological chemistry 20050506 |
| Tryptophan metabolism and oxidative stress in patients with Huntington's disease. | Journal of neurochemistry 20050501 |
| [Evaluation of the survival of bone marrow mononucleate cells transplanted in a rat model of striatal lesion with quinolinic acid]. | Revista de neurologia 20050501 |
| Involvement of the rat anterior cingulate cortex in control of instrumental responses guided by reward expectancy. | Learning & memory (Cold Spring Harbor, N.Y.) 20050501 |
| Serotonin 5-HT4 receptors and their mRNAs in rat and guinea pig brain: distribution and effects of neurotoxic lesions. | The Journal of comparative neurology 20050418 |
| Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent. | Brain research 20050408 |
| In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416. | European journal of nuclear medicine and molecular imaging 20050401 |
| Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. | American journal of physiology. Renal physiology 20050401 |
| 'Compulsive' lever pressing in rats is enhanced following lesions to the orbital cortex, but not to the basolateral nucleus of the amygdala or to the dorsal medial prefrontal cortex. | The European journal of neuroscience 20050401 |
| In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine. | Neurochemical research 20050401 |
| Divergent regulatory mechanisms governing BDNF mRNA expression in cerebral cortex and substantia nigra in response to striatal target ablation. | Experimental neurology 20050301 |
| Increase of adenine nucleotide hydrolysis in rat hippocampal slices after seizures induced by quinolinic acid. | Neurochemical research 20050301 |
| N-methyl-D-aspartate receptors are involved in the quinolinic acid, but not in the malonate pro-oxidative activity in vitro. | Neurochemical research 20050301 |
| Gestational and postnatal malnutrition affects sensitivity of young rats to picrotoxin and quinolinic acid and uptake of GABA by cortical and hippocampal slices. | Brain research. Developmental brain research 20050208 |
| Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy). | Acta neuropathologica 20050201 |
| Minocycline in phenotypic models of Huntington's disease. | Neurobiology of disease 20050201 |
| Evaluation of [123I]IBZM pinhole SPECT for the detection of striatal dopamine D2 receptor availability in rats. | NeuroImage 20050201 |
| Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum. | Journal of neurochemistry 20050201 |
| Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum. | Acta pharmacologica Sinica 20050201 |
| Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro. | Neurochemical research 20050201 |
| The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction. | Journal of the American Chemical Society 20050126 |
| The effect of orbital prefrontal cortex lesions on performance on a progressive ratio schedule: implications for models of inter-temporal choice. | Behavioural brain research 20050106 |
| Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons. | Glia 20050101 |
| Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat. | Synapse (New York, N.Y.) 20050101 |
| Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats. | Journal of neuroscience research 20050101 |
| Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo. | Transplant international : official journal of the European Society for Organ Transplantation 20050101 |
| Involvement of quinolinic acid in AIDS dementia complex. | Neurotoxicity research 20050101 |
| Identification of kynurenine pathway enzyme mRNAs and metabolites in human placenta: up-regulation by inflammatory stimuli and with clinical infection. | American journal of obstetrics and gynecology 20050101 |
| [The effects of lesions in the compact part of the substantia nigra on glutamate and GABA release in the pedunculopontine nucleus]. | Revista de neurologia 20050101 |
| Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice. | Neurochemical research 20050101 |
| Training specificity, graft development and graft-mediated functional recovery in a rodent model of Huntington's disease. | Neuroscience 20050101 |
| Communication and re-use of chemical information in bioscience. | BMC bioinformatics 20050101 |
| Quinolinic acid promotes albumin deposition in Purkinje cell, astrocytic activation and lipid peroxidation in fetal brain. | Neuroscience 20050101 |
| Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex. | Journal of neuroinflammation 20050101 |
| Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III). | Neuroscience 20050101 |
| Analysis of Escherichia coli nicotinate mononucleotide adenylyltransferase mutants in vivo and in vitro. | BMC biochemistry 20050101 |
| A computational method to predict genetically encoded rare amino acids in proteins. | Genome biology 20050101 |
| Lesions of the dorsolateral striatum impair the acquisition of a simplified stimulus-response dependent conditional discrimination task. | Neuroscience 20050101 |
| Effects of some naturally occurring iron ion chelators on in vitro superoxide radical formation. | Biological trace element research 20050101 |
| Imaging D2-receptors in quinolinic acid lesioned rat striatum with high resolution pinhole SPECT. | Nuklearmedizin. Nuclear medicine 20050101 |
| Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis. | Neuro-degenerative diseases 20050101 |
| Peroxynitrite decomposition catalyst, iron metalloporphyrin, reduces quinolinate-induced neurotoxicity in rats. | Synapse (New York, N.Y.) 20041215 |
| S-Allylcysteine, a garlic-derived antioxidant, ameliorates quinolinic acid-induced neurotoxicity and oxidative damage in rats. | Neurochemistry international 20041201 |
| Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease. | Neurobiology of disease 20041201 |
| Pharmacological manipulation of brain kynurenine metabolism. | Annals of the New York Academy of Sciences 20041201 |
| Neuroprotection by encapsulated choroid plexus in a rodent model of Huntington's disease. | Neuroreport 20041115 |
| Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression. | Biochimica et biophysica acta 20041108 |
| Multiple areas of magnetic bistability in the topological ferrimagnet [Co3(NC5H3(CO2)2-2,5)2(mu3-OH)2(OH2)2]. | Journal of the American Chemical Society 20041020 |
| Charge-transfer matrixes as a tool to desorb intact labile molecules by matrix-assisted laser desorption/ionization. Use of 2,7-dimethoxynaphthalene in the ionization of polymetallic porphyrins. | Analytical chemistry 20041015 |
| Insulin growth factor-1 protects against excitotoxicity in the rat striatum. | Neuroreport 20041005 |
| Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway. | Toxicological sciences : an official journal of the Society of Toxicology 20041001 |
| Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum. | Neurochemistry international 20041001 |
| Poloxamer 188 volumetrically decreases neuronal loss in the rat in a time-dependent manner. | Neurosurgery 20041001 |
| Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in child abuse. | Journal of neurotrauma 20040901 |
| Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine. | Brain research 20040820 |
| Changes in quinolinic acid production and its related enzymes following D-galactosamine and lipopolysaccharide-induced hepatic injury. | Archives of biochemistry and biophysics 20040815 |
| Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy. | Intensive care medicine 20040801 |
| Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion. | Journal of neurochemistry 20040801 |
| Surfactant poloxamer 188-related decreases in inflammation and tissue damage after experimental brain injury in rats. | Journal of neurosurgery 20040801 |
| Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. | The Journal of comparative neurology 20040719 |
| Progressive behavioural changes in the spatial open-field in the quinolinic acid rat model of Huntington's disease. | Behavioural brain research 20040709 |
| HIV in central nervous system and behavioral development: an HIV-2287 macaque model of AIDS. | AIDS (London, England) 20040702 |
| Overexpression, purification, and characterization of ATP-NAD kinase of Sphingomonas sp. A1. | Protein expression and purification 20040701 |
| Enhanced locomotor activity in rats with excitotoxic lesions of the entorhinal cortex, a neurodevelopmental animal model of schizophrenia: behavioral and in vivo microdialysis studies. | Neuroscience letters 20040701 |
| Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum. | Journal of neuroscience research 20040701 |
| NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice. | Epilepsia 20040701 |
| Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats. | Pain 20040701 |
| The effects of nerve growth factor upon the neuropeptide content of the suprachiasmatic nucleus of rats withdrawn from ethanol are mediated by the nucleus basalis magnocellularis. | Journal of neurocytology 20040701 |
| Effects of hippocampus and medial caudate nucleus lesions on memory for direction information in rats. | Behavioral neuroscience 20040601 |
| Brain virus burden and indoleamine-2,3-dioxygenase expression during lentiviral infection of rhesus monkey are concomitantly lowered by 6-chloro-2',3'-dideoxyguanosine. | The European journal of neuroscience 20040601 |
| Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity. | Journal of neurochemistry 20040601 |
| Polyamines reduces lipid peroxidation induced by different pro-oxidant agents. | Brain research 20040522 |
| Effects of dietary di(2-ethylhexyl)phthalate, a putative endocrine disrupter, on enzyme activities involved in the metabolism of tryptophan to niacin in rats. | Biochimica et biophysica acta 20040503 |
| Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration. | Neurochemistry international 20040501 |
| Molecular biology of pyridine nucleotide and nicotine biosynthesis. | Frontiers in bioscience : a journal and virtual library 20040501 |
| CSF quinolinic acid levels are determined by local HIV infection: cross-sectional analysis and modelling of dynamics following antiretroviral therapy. | Brain : a journal of neurology 20040501 |
| Blockade of quinolinic acid-induced neurotoxicity by pyruvate is associated with inhibition of glial activation in a model of Huntington's disease. | Experimental neurology 20040501 |
| Characterization of striatal cultures with the effect of QUIN and NMDA. | Neuroscience research 20040501 |
| AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease. | Molecular therapy : the journal of the American Society of Gene Therapy 20040501 |
| Anticonvulsant effect of GMP depends on its conversion to guanosine. | Brain research 20040416 |
| Dorsal striatum and stimulus-response learning: lesions of the dorsolateral, but not dorsomedial, striatum impair acquisition of a simple discrimination task. | Behavioural brain research 20040402 |
| The effects of intracortical endothelin-1 injections on skilled forelimb use: implications for modelling recovery of function after stroke. | Behavioural brain research 20040402 |
| On-line process monitoring of water-soluble ions in pulp and paper machine waters by capillary electrophoresis. | Journal of chromatography. A 20040402 |
| Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease. | Molecular psychiatry 20040401 |
| Glutamatergic regulation of long-term grafts of fetal lateral ganglionic eminence in a rat model of Huntington's disease. | Neurobiology of disease 20040401 |
| Quinolinic acid lesions of the caudate putamen in the rat lead to a local increase of ciliary neurotrophic factor. | Journal of anatomy 20040401 |
| Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders. | Neurochemical research 20040401 |
| Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus. | Experimental neurology 20040301 |
| Ascorbyl palmitate vesicles (Aspasomes): formation, characterization and applications. | International journal of pharmaceutics 20040301 |
| Association between inflammation and nigral neuronal damage following striatal excitotoxic lesion. | Brain research 20040213 |
| Inhibition of dopamine synthesis with alpha-methyl-p-tyrosine abolishes the enhancement of methamphetamine-induced extracellular dopamine levels in the amygdala of rats with excitotoxic lesions of the entorhinal cortex. | Neuroscience letters 20040206 |
| Evaluation with alpha-[11C]methyl-L-tryptophan positron emission tomography for reoperation after failed epilepsy surgery. | Epilepsia 20040201 |
| Excitotoxic degeneration of hypothalamic orexin neurons in slice culture. | Neurobiology of disease 20040201 |
| No nerve growth factor response to treatment with memantine in adult rats. | Journal of neural transmission (Vienna, Austria : 1996) 20040201 |
| The surfactant poloxamer-188 protects against glutamate toxicity in the rat brain. | Neuroreport 20040119 |
| Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment. | Neurology 20040113 |
| The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression. | Journal of psychiatry & neuroscience : JPN 20040101 |
| Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats. | Bioscience, biotechnology, and biochemistry 20040101 |
| Environmental enrichment affects striatal graft morphology and functional recovery. | The European journal of neuroscience 20040101 |
| [Lesions in the pars compacta substantiae nigra and the subthalamic nucleus modify the density of muscarinic receptors in different nuclei of the basal ganglia]. | Revista de neurologia 20040101 |
| Effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in mice. | Experimental animals 20040101 |
| Basal forebrain neurons modulate the synthesis and expression of neuropeptides in the rat suprachiasmatic nucleus. | Neuroscience 20040101 |
| A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases. | BMC bioinformatics 20040101 |
| Neuroprotective effects of encapsulated CNTF-producing cells in a rodent model of Huntington's disease are dependent on the proximity of the implant to the lesioned striatum. | Cell transplantation 20040101 |
| Transgenic nonhuman primates for neurodegenerative diseases. | Reproductive biology and endocrinology : RB&E 20040101 |
| Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease. | Neuroscience 20040101 |
| Basic science behind the catastrophic epilepsies. | Epilepsia 20040101 |
| Quinolinic acid induces NMDA receptor-mediated lipid peroxidation in rat brain microvessels. | Redox report : communications in free radical research 20040101 |
| Development of pathogenic concepts in glutaryl-CoA dehydrogenase deficiency: the challenge. | Journal of inherited metabolic disease 20040101 |
| Glutaric aciduria type I and kynurenine pathway metabolites: a modified hypothesis. | Journal of inherited metabolic disease 20040101 |
| Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows. | Critical reviews in neurobiology 20040101 |
| Neurotoxic and neurobehavioral effects of kynurenines in adult insects. | Biochemical and biophysical research communications 20031226 |
| A beta 1-42 induces production of quinolinic acid by human macrophages and microglia. | Neuroreport 20031219 |
| Modulation of glutamate release and excitotoxicity by adenosine A2A receptors. | Neurology 20031209 |
| Hypothalamic digoxin, hemispheric chemical dominance, and oncogenesis: evidence from multiple myeloma. | The International journal of neuroscience 20031201 |
| Deficits induced by quinolinic acid lesion to the striatum in a position discrimination and reversal task are ameliorated by permanent and temporary lesion to the globus pallidus: a potential novel treatment in a rat model of Huntington's disease. | Movement disorders : official journal of the Movement Disorder Society 20031201 |
| How to find 'missing' genes. | Chemistry & biology 20031201 |
| NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria. | Chemistry & biology 20031201 |
| Enkephalinergic striatal projection neurons become less affected by quinolinic acid than substance P-containing striatal projection neurons as rats age. | Experimental neurology 20031201 |
| Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference. | Brain research 20031114 |
| Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation. | Journal of neurochemistry 20031101 |
| A hypothalamic digoxin-mediated model for autism. | The International journal of neuroscience 20031101 |
| Motor training effects on recovery of function after striatal lesions and striatal grafts. | Experimental neurology 20031101 |
| Modulation of stress-induced dopamine release by excitotoxic damage of the entorhinal cortex in the rat. | Brain research 20031031 |
| [(Th2F5)(NC7H5O4)2(H2O)][NO3]: an actinide-organic open framework. | Journal of the American Chemical Society 20031022 |
| Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents. | Experimental neurology 20031001 |
| c-fos and tyrosine hydroxylase expression after an excitotoxic lesion on the nigrostriatal system: a study on the effects of hypoxia used as a preconditioning stimulus. | Experimental neurology 20031001 |
| Neuroprotective effects of pyruvate in the quinolinic acid rat model of Huntington's disease. | Experimental neurology 20031001 |
| Reactions of the dirhenium(II) complex Re2Cl4(mu-dppm)2 with pyridinecarboxylic acids. Examples of bidentate O,O versus N,O coordination and tridentate O,N,O coordination and structural isomers that contain the pyridine-2,6-dicarboxylate ligand. | Inorganic chemistry 20030922 |
| Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. | The Journal of infectious diseases 20030915 |
| A one-dimensional zigzag coordination polymer: catena-poly[[diaquapyridinenickel(II)]-mu-pyridine-2,3-dicarboxylato-kappa3N,O2:O3]. | Acta crystallographica. Section C, Crystal structure communications 20030901 |
| Regioselective hydroxylation of quinolinic acid, lutidinic acid and isocinchomeronic acid by resting cells of pyridine dicarboxylic acid-degrading microorganisms. | Applied microbiology and biotechnology 20030901 |
| Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain. | The European journal of neuroscience 20030901 |
| Preserved sensitivity to outcome value after lesions of the basolateral amygdala. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820 |
| Copper blocks quinolinic acid neurotoxicity in rats: contribution of antioxidant systems. | Free radical biology & medicine 20030815 |
| Synthesis, structure, and photoelectronic effects of a uranium-zinc-organic coordination polymer containing infinite metal oxide sheets. | Journal of the American Chemical Society 20030806 |
| Effects of undernutrition on glutamatergic parameters in rat brain. | Neurochemical research 20030801 |
| Quinolinate dehydrogenase and 6-hydroxyquinolinate decarboxylase involved in the conversion of quinolinic acid to 6-hydroxypicolinic acid by Alcaligenes sp. strain UK21. | Archives of microbiology 20030801 |
| Tryptophan and the immune response. | Immunology and cell biology 20030801 |
| Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects. | Current medicinal chemistry 20030801 |
| Hypothalamic digoxin, hemispheric chemical dominance, and eating behavior. | The International journal of neuroscience 20030801 |
| A one-dimensional zigzag coordination polymer of diaqua(pyridine-2,3-dicarboxylato)cobalt(II). | Acta crystallographica. Section C, Crystal structure communications 20030801 |
| Adenosine A(2A) antagonism increases striatal glutamate outflow in the quinolinic acid rat model of Huntington's disease. | Brain research 20030725 |
| Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice. | Brain research 20030704 |
| Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. | The Journal of pharmacology and experimental therapeutics 20030701 |
| Behavioral/neurophysiological investigation of effects of combining a quinolinic acid entopeduncular lesion with a fetal mesencephalic tissue transplant in striatum of the 6-OHDA hemilesioned rat. | Synapse (New York, N.Y.) 20030701 |
| Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase of Helicobacter pylori. | Acta crystallographica. Section D, Biological crystallography 20030701 |
| Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vitro and in vivo studies. | Journal of neurochemistry 20030701 |
| The concept of cerebral chemical dominance. | The International journal of neuroscience 20030701 |
| Tryptophan metabolites and brain disorders. | Clinical chemistry and laboratory medicine 20030701 |
| GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults. | The Journal of comparative neurology 20030630 |
| Effects of lomefloxacin and norfloxacin on pancreatic beta-cell ATP-sensitive K(+) channels. | Life sciences 20030613 |
| Cytokines, neurophysiology, neuropsychology, and psychiatric symptoms. | Dialogues in clinical neuroscience 20030601 |
| Hypothalamic digoxin, cerebral chemical dominance and myalgic encephalomyelitis. | The International journal of neuroscience 20030501 |
| Hypothalamic digoxin, hemispheric dominance, and neurobiology of love and affection. | The International journal of neuroscience 20030501 |
| [Glutamate receptor dysfunction and psychosis-like behavior in an animal model]. | Ceskoslovenska fysiologie 20030501 |
| Contribution of quinolinic acid in the development of anemia in renal insufficiency. | American journal of physiology. Renal physiology 20030401 |
| [Septic encephalopathy. Diagnosis und therapy]. | Der Anaesthesist 20030401 |
| Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury. | Journal of molecular neuroscience : MN 20030401 |
| Hypothalamic digoxin-mediated model for Parkinson's disease. | The International journal of neuroscience 20030401 |
| Hypothalamic digoxin, hemispheric chemical dominance, and creativity. | The International journal of neuroscience 20030401 |
| Pre- or post-treatment with the mitochondrial uncoupler 2,4-dinitrophenol attenuates striatal quinolinate lesions. | Brain research 20030321 |
| Capillary electrophoretic separation of dicarboxylic acids in atmospheric aerosol particles. | Journal of chromatography. A 20030321 |
| Effects of adrenal medulla graft on recovery of GABAergic and dopaminergic neuron deficits in mice: behavioural, pharmacological and immunohistochemical study. | Behavioural brain research 20030318 |
| Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes. | Glia 20030301 |
| Hypothalamic digoxin, hemispheric chemical dominance, and Alzheimer's disease. | The International journal of neuroscience 20030301 |
| Hypothalamic digoxin, hemispheric chemical dominance, and spirituality. | The International journal of neuroscience 20030301 |
| Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215 |
| Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells. | The Journal of biological chemistry 20030207 |
| Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030201 |
| Hypothalamic digoxin--central role in conscious perception, neuroimmunoendocrine integration and coordination of cellular function--relation to hemispheric dominance. | Medical hypotheses 20030201 |
| Quetiapine produces a prolonged reversal of the sensorimotor gating-disruptive effects of basolateral amygdala lesions in rats. | Behavioral neuroscience 20030201 |
| Dipicolinic acid prevents the copper-dependent oxidation of low density lipoprotein. | The Journal of nutritional biochemistry 20030201 |
| The action of mexidol on the state of conditioned reflex activity after traumatic brain lesions. | Neuroscience and behavioral physiology 20030201 |
| Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation. | Journal of neuroscience research 20030115 |
| alpha-[11C]-Methyl-L-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency. | Epilepsy research 20030101 |
| Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition. | Neurotoxicity research 20030101 |
| Isoprenoid pathway related cascade in multiple myeloma. | Pathology oncology research : POR 20030101 |
| Comparative inhibition by substrate analogues 3-methoxy- and 3-hydroxydesaminokynurenine and an improved 3 step purification of recombinant human kynureninase. | BMC biochemistry 20030101 |
| Basolateral amygdala lesions impair both cue- and cocaine-induced reinstatement in animals trained on a discriminative stimulus task. | Neuroscience 20030101 |
| Cytokine-serotonin interaction through IDO: a neurodegeneration hypothesis of depression. | Medical hypotheses 20030101 |
| Hypothalamic digoxin-mediated model for trisomy 21. | Pediatric pathology & molecular medicine 20030101 |
| Quinolinic acid up-regulates chemokine production and chemokine receptor expression in astrocytes. | Advances in experimental medicine and biology 20030101 |
| Expression of the kynurenine pathway enzymes in human microglia and macrophages. | Advances in experimental medicine and biology 20030101 |
| Studies on the neuroprotective action of kynurenine mono-oxygenase inhibitors in post-ischemic brain damage. | Advances in experimental medicine and biology 20030101 |
| 3-Hydroxykynurenine and quinolinate: pathogenic synergism in early grade Huntington's disease? | Advances in experimental medicine and biology 20030101 |
| Accumulation of quinolinic acid with neuroinflammation: does it mean excitotoxicity? | Advances in experimental medicine and biology 20030101 |
| Quinolinic acid in the pathogenesis of Alzheimer's disease. | Advances in experimental medicine and biology 20030101 |
| Kynurenine metabolism in central nervous system in experimental chronic renal failure. | Advances in experimental medicine and biology 20030101 |
| Neurokynurenines--seizures or/and anxiety in children with epilepsy? | Advances in experimental medicine and biology 20030101 |
| Neuropeptide-containing cells in the cortex and striatum of mice with cerebral malaria. | Advances in experimental medicine and biology 20030101 |
| Increase in conversion of tryptophan to niacin in pregnant rats. | Advances in experimental medicine and biology 20030101 |
| Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis. | Advances in experimental medicine and biology 20030101 |
| Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum. | Advances in experimental medicine and biology 20030101 |
| ECNI GC-MS analysis of picolinic and quinolinic acids and their amides in human plasma, CSF, and brain tissue. | Advances in experimental medicine and biology 20030101 |
| Sustainable production of bioactive compounds from sponges: primmorphs as bioreactors. | Progress in molecular and subcellular biology 20030101 |
| The frontal cortex of the rat and visual attentional performance: dissociable functions of distinct medial prefrontal subregions. | Cerebral cortex (New York, N.Y. : 1991) 20021201 |
| Effects of quinolinic acid-induced lesions of the orbital prefrontal cortex on inter-temporal choice: a quantitative analysis. | Psychopharmacology 20021201 |
| Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions. | Experimental neurology 20021201 |
| Hypothalamic digoxin and regulation of body mass index. | Neurology India 20021201 |
| Identification of a toxic mechanism of the plasticizers, phtahlic acid esters, which are putative endocrine disrupters: time-dependent increase in quinolinic acid and its metabolites in rats fed di(2-ethylhexyl)phthalate. | Bioscience, biotechnology, and biochemistry 20021201 |
| Synthesis of the neurotoxin quinolinic acid in apoptotic tissue from Suberites domuncula: cell biological, molecular biological, and chemical analyses. | Marine biotechnology (New York, N.Y.) 20021201 |
| Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease. | Human gene therapy 20021101 |
| Adenosine A2A receptor imaging with [11C]KF18446 PET in the rat brain after quinolinic acid lesion: comparison with the dopamine receptor imaging. | Annals of nuclear medicine 20021101 |
| T cell apoptosis by tryptophan catabolism. | Cell death and differentiation 20021001 |
| Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Neopterin and quinolinic acid are surrogate measures of disease activity in the juvenile idiopathic inflammatory myopathies. | Clinical chemistry 20021001 |
| HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes. | Journal of acquired immune deficiency syndromes (1999) 20021001 |
| Characterization of neurotransmitters and dopamine attenuation of inducible nitric oxide synthase in glioma cells. | Journal of neuroimmunology 20021001 |
| Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and 'quinolinate hypothesis'. | The Journal of biological chemistry 20020920 |
| Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. | Journal of neurochemistry 20020901 |
| Drug targeting to the brain: transfer of picolinic acid along the olfactory pathways. | Journal of drug targeting 20020901 |
| SCH 58261 differentially influences quinolinic acid-induced effects in striatal and in hippocampal slices. | European journal of pharmacology 20020830 |
| Learning and memory in two different reward tasks in a radial arm maze in rats. | Behavioural brain research 20020821 |
| Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts. | American journal of veterinary research 20020801 |
| Cholinergic receptor activity after quinolinic acid caused cerebral injury in rats. | Chinese medical journal 20020801 |
| N-Methyl-D-aspartate receptor subtype-selectivity of homoquinolinate: an electrophysiological and radioligand binding study using both native and recombinant receptors. | Journal of neurochemistry 20020801 |
| Apoptosis of oligodendrocytes in secondary cultures from neonatal rat brains. | Neuroscience letters 20020719 |
| LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors. | Analytical biochemistry 20020715 |
| The pharmacological manipulation of glutamate receptors and neuroprotection. | European journal of pharmacology 20020705 |
| Habituation and cross-sensitization of stress-induced hypothalamic-pituitary-adrenal activity: effect of lesions in the paraventricular nucleus of the thalamus or bed nuclei of the stria terminalis. | Journal of neuroendocrinology 20020701 |
| Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain. | Journal of neurochemistry 20020701 |
| [Microanalysis of tryptophan metabolites and suppressor factor of delayed-type hypersensitivity in mice]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020701 |
| Neurobiology of ammonia. | Progress in neurobiology 20020701 |
| Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. | British journal of cancer 20020605 |
| Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes. | Neurochemistry international 20020601 |
| Synaptic localization of GABA(A) receptor subunits in the substantia nigra of the rat: effects of quinolinic acid lesions of the striatum. | The European journal of neuroscience 20020601 |
| Endogenous sodium-potassium ATPase inhibition related biochemical cascade in trisomy 21 and Huntington's disease: neural regulation of genomic function. | Neurology India 20020601 |
| Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats. | Bioscience, biotechnology, and biochemistry 20020601 |
| Central role of hypothalamic digoxin in conscious perception, neuroimmunoendocrine integration, and coordination of cellular function: relation to hemispheric dominance. | The International journal of neuroscience 20020601 |
| Tryptophan metabolism in alcoholism. | Nutrition research reviews 20020601 |
| Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra. | Experimental neurology 20020501 |
| Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease. | Experimental neurology 20020501 |
| Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+. | Biochimica et biophysica acta 20020429 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum. | Experimental neurology 20020401 |
| Positron emission tomography and ex vivo and in vitro autoradiography studies on dopamine D2-like receptor degeneration in the quinolinic acid-lesioned rat striatum: comparison of [11C]raclopride, [11C]nemonapride and [11C]N-methylspiperone. | Nuclear medicine and biology 20020401 |
| Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain. | Neurochemical research 20020401 |
| Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS. | The European journal of neuroscience 20020401 |
| Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent. | Journal of neurochemistry 20020401 |
| Neuroprotective effects of lithium in cultured cells and animal models of diseases. | Bipolar disorders 20020401 |
| Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors. | The Journal of comparative neurology 20020318 |
| Hunting for excitement: NMDA receptors in Huntington's disease. | Neuron 20020314 |
| Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. | Neuron 20020314 |
| Quinolinate phosphoribosyltransferase: kinetic mechanism for a type II PRTase. | Biochemistry 20020312 |
| Mechanisms of the protective effect of L-alanine to D-galactosamine-induced hepatocellular injury: comparative studies of L-alanine and pyruvate. | Biochemical and biophysical research communications 20020308 |
| The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. | The Journal of infectious diseases 20020301 |
| Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure. | Nephron 20020301 |
| Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
| Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. | Journal of neurobiology 20020301 |
| Enhanced neuronal damage by co-administration of quinolinic acid and free radicals, and protection by adenosine A2A receptor antagonists. | British journal of pharmacology 20020301 |
| Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum. | Journal of neural transmission (Vienna, Austria : 1996) 20020301 |
| Endogenous neurotoxine-quinolinic acid is increased in renal allograft recipients. | Transplantation proceedings 20020301 |
| Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat. | Neuroscience letters 20020201 |
| Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry. | Analytical biochemistry 20020201 |
| Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice. | Journal of neuroscience research 20020201 |
| The effects of prelimbic and infralimbic lesions on working memory for visual objects in rats. | Neurobiology of learning and memory 20020101 |
| Identification of CD40 ligand in Alzheimer's disease and in animal models of Alzheimer's disease and brain injury. | Neurobiology of aging 20020101 |
| Function of the hypothalamo-pituitary-adrenocortical system during ontogenesis in rats with inherited stress-induced arterial hypertension. | Neuroscience and behavioral physiology 20020101 |
| The role of the ventrolateral nucleus of the thalamus in the switching of descending influences to motor activity in the rat. | Neuroscience and behavioral physiology 20020101 |
| Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease. | Neurosurgery 20020101 |
| Effects of nerve and fibroblast growth factors on the production of nitric oxide in experimental model of Huntington's disease. | Vojnosanitetski pregled 20020101 |
| Fetal striatal transplants restore electrophysiological sensitivity to dopamine in the lesioned striatum of rats with experimental Huntington's disease. | Journal of biomedical science 20020101 |
| Detailed localization of regulator of G protein signaling 2 messenger ribonucleic acid and protein in the rat brain. | Neuroscience 20020101 |
| Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture. | Genome biology 20020101 |
| Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus. | Physiological research 20020101 |
| Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease. | Redox report : communications in free radical research 20020101 |
| A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis. | Neuroscience 20020101 |
| Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum. | Experimental brain research 20011201 |
| TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia. | Experimental neurology 20011201 |
| Metabolic changes in quinolinic acid-lesioned rat striatum detected non-invasively by in vivo (1)H NMR spectroscopy. | Journal of neuroscience research 20011201 |
| 17Beta-estradiol attenuates quinolinic acid insult in the rat hippocampus. | Metabolic brain disease 20011201 |
| Kynurenine and its metabolites in the rat with experimental renal insufficiency. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201 |
| IFN-beta1b induces kynurenine pathway metabolism in human macrophages: potential implications for multiple sclerosis treatment. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20011201 |
| Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome. | The European journal of neuroscience 20011201 |
| Hypothalamic digoxin mediated model for oncogenesis. | Journal of experimental & clinical cancer research : CR 20011201 |
| Lesions of the basolateral amygdala disrupt selective aspects of reinforcer representation in rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011115 |
| Localizing value of alpha-methyl-L-tryptophan PET in intractable epilepsy of neocortical origin. | Neurology 20011113 |
| Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages. | Journal of neuroimmunology 20011101 |
| Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine. | The European journal of neuroscience 20011101 |
| Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene. | The European journal of neuroscience 20011101 |
| The possible crucial role of iron accumulation combined with low tryptophan, zinc and manganese in carcinogenesis. | Medical hypotheses 20011101 |
| IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures. | Journal of inherited metabolic disease 20011101 |
| Differential expression of active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat. | Brain research. Molecular brain research 20011019 |
| The role of the primate amygdala in conditioned reinforcement. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001 |
| Increased cortical kynurenate content in schizophrenia. | Biological psychiatry 20011001 |
| Kynurenine production and catabolism in fetal sheep with embolized or nonembolized placentas. | American journal of obstetrics and gynecology 20011001 |
| Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats. | Bioscience, biotechnology, and biochemistry 20011001 |
| Effect of orally administered guanosine on seizures and death induced by glutamatergic agents. | Brain research 20010907 |
| Basolateral amygdala lesions disrupt latent inhibitionin rats. | Brain research bulletin 20010901 |
| In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum. | Neuroreport 20010828 |
| The role of rat dorsomedial prefrontal cortex in working memory for egocentric responses. | Neuroscience letters 20010810 |
| Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection. | Journal of neurochemistry 20010801 |
| Glyoxylate determination in rat urine by capillary electrophoresis. | International journal of urology : official journal of the Japanese Urological Association 20010801 |
| Role of the medial and lateral caudate-putamen in mediating an auditory conditional response association. | Neurobiology of learning and memory 20010701 |
| Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat. | Brain research bulletin 20010701 |
| Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. | Progress in neurobiology 20010601 |
| Role of the striatum and nucleus accumbens in paced copulatory behavior in the female rat. | Behavioural brain research 20010601 |
| Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury. | Brain research 20010601 |
| Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid. | Journal of neurochemistry 20010601 |
| Expression of cyclin-dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo. | Journal of neurochemistry 20010601 |
| Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. | Neurobiology of disease 20010601 |
| Quinolinic acid accumulation during neuroinflammation. Does it imply excitotoxicity? | Annals of the New York Academy of Sciences 20010601 |
| Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. | Bioscience, biotechnology, and biochemistry 20010601 |
| [Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats]. | Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601 |
| Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo. | Neuroscience letters 20010525 |
| Rolipram reduces excitotoxic neuronal damage. | Neuroreport 20010525 |
| Prenatal exposure to methyl mercury in rats: focus on changes in kynurenine pathway. | Brain research bulletin 20010515 |
| Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection. | Brain : a journal of neurology 20010501 |
| Dissociable contributions of the orbitofrontal and lateral prefrontal cortex of the marmoset to performance on a detour reaching task. | The European journal of neuroscience 20010501 |
| Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction. | Free radical research 20010501 |
| Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development. | Neurochemical research 20010501 |
| Prostaglandin A(1) protects striatal neurons against excitotoxic injury in rat striatum. | The Journal of pharmacology and experimental therapeutics 20010401 |
| Kynurenic acid antagonists and kynurenine pathway inhibitors. | Expert opinion on investigational drugs 20010401 |
| Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease. | Neurochemical research 20010401 |
| Oligodendrocyte killing by quinolinic acid in vitro. | Brain research 20010330 |
| Quinolinic acid induces oxidative stress in rat brain synaptosomes. | Neuroreport 20010326 |
| CPI-1189 attenuates effects of suspected neurotoxins associated with AIDS dementia: a possible role for ERK activation. | Brain research 20010302 |
| Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus. | The European journal of neuroscience 20010201 |
| Kynurenic acid influences the respiratory parameters of rat heart mitochondria. | Pharmacology 20010201 |
| The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats. | Psychopharmacology 20010201 |
| The effects of nucleus accumbens core and shell lesions on intravenous heroin self-administration and the acquisition of drug-seeking behaviour under a second-order schedule of heroin reinforcement. | Psychopharmacology 20010201 |
| A sensitive and reliable method for the detection of lipid peroxidation in biological tissues. | The Journal of pharmacy and pharmacology 20010201 |
| Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat. | Journal of neurovirology 20010201 |
| Endogenous neurotoxins from tryptophan. | Toxicon : official journal of the International Society on Toxinology 20010101 |
| The nicotinamide biosynthetic pathway is a by-product of the RNA world. | Journal of molecular evolution 20010101 |
| N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition. | Journal of neurochemistry 20010101 |
| Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101 |
| The biosynthesis of nicotinamide adenine dinucleotides in bacteria. | Vitamins and hormones 20010101 |
| Simultaneous intrastriatal 6-hydroxydopamine and quinolinic acid injection: a model of early-stage striatonigral degeneration. | Experimental neurology 20010101 |
| The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity. | Experimental neurology 20010101 |
| Regional changes in kynurenic acid, quinolinic acid, and glial fibrillary acidic protein concentrations in the fetal sheep brain after experimentally induced placental insufficiency. | American journal of obstetrics and gynecology 20010101 |
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