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87333-19-5

87333-19-5 | Ramipril

CAS No: 87333-19-5 Catalog No: AG003AXG MDL No:MFCD00865775

Product Description

Catalog Number:
AG003AXG
Chemical Name:
Ramipril
CAS Number:
87333-19-5
Molecular Formula:
C23H32N2O5
Molecular Weight:
416.5106
MDL Number:
MFCD00865775
IUPAC Name:
(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
InChI:
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChI Key:
HDACQVRGBOVJII-JBDAPHQKSA-N
SMILES:
CCOC(=O)C(NC(C(=O)N1C2CCCC2CC1C(=O)O)C)CCc1ccccc1
UNII:
L35JN3I7SJ
NSC Number:
758933

Properties

Complexity:
619  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0
Exact Mass:
416.231g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
416.518g/mol
Monoisotopic Mass:
416.231g/mol
Rotatable Bond Count:
10  
Topological Polar Surface Area:
95.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  

Literature

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Heart failure prognostic model. Journal of medicine and life 20110515
Development of a capillary electrophoresis method for the assay of ramipril and its impurities: an issue of cis-trans isomerization. Journal of chromatography. A 20110506
Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devices. European heart journal 20110501
BR-squared: a practical solution to the winner's curse in genome-wide scans. Human genetics 20110501
Hypertension augments cardiac Toll-like receptor 4 expression and activity. Hypertension research : official journal of the Japanese Society of Hypertension 20110501
Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic. Diabetes 20110501
Long-term effects of Irbesartan treatment and smoking on nucleic acid oxidation in patients with type 2 diabetes and microalbuminuria: an Irbesartan in patients with type 2 diabetes and Microalbuminuria (IRMA 2) substudy. Diabetes care 20110501
Impact of natriuretic peptide clearance receptor (NPR3) gene variants on blood pressure in type 2 diabetes. Diabetes care 20110501
Type 2 diabetes can be prevented with early pharmacological intervention. Diabetes care 20110501
Impact of methylation of acyl glucuronide metabolites on incurred sample reanalysis evaluation: ramiprilat case study. Bioanalysis 20110501
Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured L6 myotubes and RIN-5F pancreatic β-cells. Journal of clinical biochemistry and nutrition 20110501
An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect. Clinics (Sao Paulo, Brazil) 20110501
Telmisartan: a review of its use in cardiovascular disease prevention. Drugs 20110416
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Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection. Bioscience reports 20110401
Unexpected hospitalisation side effects in an elderly man. Internal and emergency medicine 20110401
Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies. Journal of clinical pharmacology 20110401
Simultaneous determination of atorvastatin, amlodipine, ramipril and benazepril in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. Biomedical chromatography : BMC 20110401
Impact of nephron number dosing on cardiorenal damage and effects of ACE inhibition. American journal of hypertension 20110401
Circadian rhythms in blood pressure regulation and optimization of hypertension treatment with ACE inhibitor and ARB medications. American journal of hypertension 20110401
Antihypertensive efficacy and safety of olmesartan and ramipril in elderly patients with mild to moderate systolic and diastolic essential hypertension. Blood pressure. Supplement 20110401
Angiotensin-(1-7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy. Clinical science (London, England : 1979) 20110401
Asymmetric posterior reversible encephalopathy syndrome in patient with hyperplastic anterior choroidal artery. The journal of headache and pain 20110401
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Diabetes treatment and cardiovascular safety. Diabetes care 20110401
Achieving blood preSsure goals sTudy in uncontrolled hypeRtensive pAtients treated with a fixed-dose combination of ramipriL/hydrochlorothiazide: the ASTRAL study. Cardiovascular journal of Africa 20110401
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Using routinely collected prescribing data to determine drug persistence for the purpose of pharmacovigilance. Journal of clinical pharmacology 20110201
Combined atorvastatin and ramipril mitigate radiation-induced impairment of dentate gyrus neurogenesis. Journal of neuro-oncology 20110201
Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations. British journal of pharmacology 20110201
Stimulation of cardiac apoptosis in ovariectomized hypertensive rats: potential role of the renin-angiotensin system. Journal of hypertension 20110201
Treatment of heart failure with normal ejection fraction. Current treatment options in cardiovascular medicine 20110201
Impact of prolonged antihypertensive duration of action on predicted clinical outcomes in imperfectly adherent patients: comparison of aliskiren, irbesartan and ramipril. International journal of clinical practice 20110201
Type 2 diabetes: uses of thiazolidinediones and insulin. Diabetes care 20110201
Low-dose aspirin therapy in patients with type 2 diabetes and reduced glomerular filtration rate: subanalysis from the JPAD trial. Diabetes care 20110201
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World Kidney Day 2011 - Protect your kidneys, save your heart. Archives of medical science : AMS 20110201
Simultaneous determination of ramipril, ramiprilat and telmisartan in human plasma using liquid chromatography tandem mass spectrometry. Talanta 20110115
Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina. Journal of human hypertension 20110101
Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets. Molecular and cellular endocrinology 20110101
Effect of Treatment of Sprague Dawley Rats with AVE7688, Enalapril, or Candoxatril on Diet-Induced Obesity. Journal of obesity 20110101
ACE inhibitors for the treatment of hypertension drug selection by means of the SOJA method. Reviews on recent clinical trials 20110101
Weight considerations in pharmacotherapy for type 2 diabetes. Journal of obesity 20110101
Effect of adding pharmacists to primary care teams on blood pressure control in patients with type 2 diabetes: a randomized controlled trial. Diabetes care 20110101
Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies. The Lancet. Neurology 20110101
Different actions of losartan and ramipril on adipose tissue activity and vascular remodeling biomarkers in hypertensive patients. Hypertension research : official journal of the Japanese Society of Hypertension 20110101
Comparison of the effects of losartan vs. ramipril on several adipocytokines and vascular remodeling biomarkers. Hypertension research : official journal of the Japanese Society of Hypertension 20110101
Compliance, persistence, healthcare resource use, and treatment costs associated with aliskiren plus ARB versus ACE inhibitor plus ARB combination therapy: in US patients with hypertension. American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101
Integrative bioinformatics analysis of proteins associated with the cardiorenal syndrome. International journal of nephrology 20110101
Standards of medical care in diabetes--2011. Diabetes care 20110101
Impact of ACE inhibitors on mortality and morbidity in patients with AMI: Does tissue selectivity matter? Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101
Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial. BMC psychiatry 20110101
Heart-kidney interaction: epidemiology of cardiorenal syndromes. International journal of nephrology 20110101
Resistant hypertension workup and approach to treatment. International journal of hypertension 20110101
Effect of primary care physicians' use of estimated glomerular filtration rate on the timing of their subspecialty referral decisions. BMC nephrology 20110101
Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study. Cardiovascular diabetology 20110101
Pharmacological and non-pharmacological interventions to influence adipose tissue function. Cardiovascular diabetology 20110101
High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy. PloS one 20110101
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Cardiorenal syndrome type 4-cardiovascular disease in patients with chronic kidney disease: epidemiology, pathogenesis, and management. International journal of nephrology 20110101
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A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial. Trials 20110101
Aggressive cardiac involvement in systemic lupus erythematosus: a case report and a comprehensive literature review. Cardiology research and practice 20110101
Spontaneous coronary artery dissection in a young man - case report. Journal of cardiothoracic surgery 20110101
Telmisartan in incipient and overt diabetic renal disease. Journal of nephrology 20110101
Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial. Trials 20110101
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Common secondary causes of resistant hypertension and rational for treatment. International journal of hypertension 20110101
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Anastrozole-related acute hepatitis with autoimmune features: a case report. BMC gastroenterology 20110101
Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care. BMC public health 20110101
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Olmesartan/amlodipine: a review of its use in the management of hypertension. Vascular health and risk management 20110101
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Simultaneous, noninvasive, and transdermal extraction of urea and homocysteine by reverse iontophoresis. International journal of nanomedicine 20110101
Angiotensin receptor blockers and risk of myocardial infarction: meta-analyses and trial sequential analyses of 147 020 patients from randomised trials. BMJ (Clinical research ed.) 20110101
Cardiovascular and Renal Links along the Cardiorenal Continuum. International journal of nephrology 20110101
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A validated densitometric method for analysis of atorvastatin calcium and metoprolol tartarate as bulk drugs and in combined capsule dosage forms. Journal of young pharmacists : JYP 20110101
Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography. Scientia pharmaceutica 20110101
Combination delapril/manidipine as antihypertensive therapy in high-risk patients. Clinical drug investigation 20110101
Reappraisal of role of angiotensin receptor blockers in cardiovascular protection. Vascular health and risk management 20110101
A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors. Vascular health and risk management 20110101
Peripheral vascular dysfunction in chronic kidney disease. Cardiology research and practice 20110101
Salmonella enteritidis Infection Complicated by Acute Myocarditis: A Case Report and Review of the Literature. Cardiology research and practice 20110101
Modulation of hemodynamics, endogenous antioxidant enzymes, and pathophysiological changes by Angiotensin-converting enzyme inhibitors in pressure-overload rats. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101
[Ten years after publishing results from The Heart Outcomes Prevention Evaluation Study--HOPE: implications on treatment with angiotensin converting enzyme inhibitors in clinical practice]. Lijecnicki vjesnik 20110101
An international randomised placebo-controlled trial of a four-component combination pill ('polypill') in people with raised cardiovascular risk. PloS one 20110101
Collagenofibrotic glomerulopathy - Case report with review of literature. Indian journal of nephrology 20110101
Into the future: prevention of diabetes. Contributions to nephrology 20110101
Efficacy of aliskiren/hydrochlorothiazide combination for the treatment of hypertension: a meta-analytical approach. The open cardiovascular medicine journal 20110101
Cardiac arrest caused by torsades de pointes tachycardia after successful atrial flutter radiofrequency catheter ablation. The open cardiovascular medicine journal 20110101
A complex renal cyst: it is time to call the oncologist? International journal of nephrology 20110101
Awareness of Abdominal Adiposity as a Cardiometabolic Risk Factor (The 5A Study): Mexico. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
The vulnerable plaque: the real villain in acute coronary syndromes. The open cardiovascular medicine journal 20110101
Aliskiren: An orally active renin inhibitor. Journal of pharmacy & bioallied sciences 20110101
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Critical appraisal of irrational drug combinations: A call for awareness in undergraduate medical students. Journal of pharmacology & pharmacotherapeutics 20110101
Accounting for the mortality benefit of drug-eluting stents in percutaneous coronary intervention: a comparison of methods in a retrospective cohort study. BMC medicine 20110101
Multiple unit particles system of ramipril: an approach to enhance stability. Journal of young pharmacists : JYP 20110101
Hypertension in chronic kidney disease: navigating the evidence. International journal of hypertension 20110101
Management of High Blood Pressure in Those without Overt Cardiovascular Disease Utilising Absolute Risk Scores. International journal of hypertension 20110101
The mechanosensory role of primary cilia in vascular hypertension. International journal of vascular medicine 20110101
Oxidative stress in cardiovascular inflammation: its involvement in autoimmune responses. International journal of inflammation 20110101
New onset diabetes after transplantation (NODAT): an overview. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Diabetic nephropathy - Epidemiology in Asia and the current state of treatment. Indian journal of nephrology 20110101
Biological activities of chinese propolis and brazilian propolis on streptozotocin-induced type 1 diabetes mellitus in rats. Evidence-based complementary and alternative medicine : eCAM 20110101
Management of Hypertension among Patients with Coronary Heart Disease. International journal of hypertension 20110101
Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial. BMJ (Clinical research ed.) 20110101
Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials. BMJ (Clinical research ed.) 20110101
Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey. Drug design, development and therapy 20110101
Cardiovascular outcomes with angiotensin II receptor blockers: clinical implications of recent trials. Vascular health and risk management 20110101
Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil. Vascular health and risk management 20110101
Use of TIVA for Mandibular Plating in a Patient with Takayasu's Disease. Journal of anaesthesiology, clinical pharmacology 20110101
Perioperative atrial fibrillation in five patients - role of anxiety. Journal of anaesthesiology, clinical pharmacology 20110101
Suboptimal use of risk reduction therapy in peripheral arterial disease patients at a major teaching hospital. Annals of Saudi medicine 20110101
Angiotensin-receptor blockade in acute stroke. Annals of Indian Academy of Neurology 20110101
Animal models of calcific aortic valve disease. International journal of inflammation 20110101
Neuroprotective effect of ACE inhibitors in glutamate - induced neurotoxicity: rat neuron culture study. Turkish neurosurgery 20110101
Management of metformin-associated lactic acidosis by continuous renal replacement therapy. PloS one 20110101
Effects of angiotensin-converting enzyme inhibitors beyond lowering blood pressure--are they important for doctors? Pharmacological reports : PR 20110101
Role of Bone Morphogenetic Proteins-7 (BMP-7) in the Renal Improvement Effect of DangGui (Angelica sinensis) in Type-1 Diabetic Rats. Evidence-based complementary and alternative medicine : eCAM 20110101
ARBs for cardiovascular and renal protection in high-risk patients. Cardiovascular journal of Africa 20110101
Trends in the Use of Evidence-based Therapies Early in the Course of Acute Myocardial Infarction and its Influence on Short Term Patient Outcomes. The open cardiovascular medicine journal 20110101
Validated RP-HPLC Method for Simultaneous Quantitation of Losartan Potassium and Metolazone in Bulk Drug and Formulation. Scientia pharmaceutica 20110101
Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension. PloS one 20110101
Anesthetic management for laparoscopy surgery in a patient with residual coarctation of aorta and mild aortic stenosis. Journal of anaesthesiology, clinical pharmacology 20110101
Formulation and evaluation of solid lipid nanoparticles of ramipril. Journal of young pharmacists : JYP 20110101
Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models. PloS one 20110101
Rituximab resistant evans syndrome and autoimmunity in Schimke immuno-osseous dysplasia. Pediatric rheumatology online journal 20110101
Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study. BMC nephrology 20110101
Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients. BMC cardiovascular disorders 20110101
Pharmacovigilance analysis of adverse event reports for aliskiren hemifumarate, a first-in-class direct renin inhibitor. Therapeutics and clinical risk management 20110101
Long-term use and tolerability of irbesartan for control of hypertension. Integrated blood pressure control 20110101
Clinical utility of fixed-combination telmisartan-amlodipine in the treatment of hypertension. Integrated blood pressure control 20110101
Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients. Integrated blood pressure control 20110101
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Inhibition of cardiac sympathetic afferent reflex and sympathetic activity by baroreceptor and vagal afferent inputs in chronic heart failure. PloS one 20110101
Cost-effectiveness of angiotensin-converting enzyme inhibitors for the prevention of diabetic nephropathy in The Netherlands--a Markov model. PloS one 20110101
Appreciating the medical literature: five notable articles in general internal medicine from 2009 and 2010. Open medicine : a peer-reviewed, independent, open-access journal 20110101
Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation. Chemistry Central journal 20110101
Changes in clinical profile, treatment, and mortality in patients hospitalised for acute myocardial infarction between 1985 and 2008. PloS one 20110101
Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device. Journal of cardiothoracic surgery 20110101
Estrogen receptor alpha expression in podocytes mediates protection against apoptosis in-vitro and in-vivo. PloS one 20110101
Indications for and utilization of angiotensin receptor II blockers in patients at high cardiovascular risk. Vascular health and risk management 20110101
A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting. Journal of cardiothoracic surgery 20110101
Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance. Lipids in health and disease 20110101
The impact of dose of the angiotensin-receptor blocker valsartan on the post-myocardial infarction ventricular remodeling: study protocol for a randomized controlled trial. Trials 20110101
Single coronary artery with anomalous rising of the right coronary artery: a rare coronary anomaly diagnosed by 256-multidetector computed tomography. Case reports in medicine 20110101
A cluster randomised pragmatic trial applying Self-determination theory to type 2 diabetes care in general practice. BMC family practice 20110101
Peritoneal Dialysis Drop-out: Causes and Prevention Strategies. International journal of nephrology 20110101
Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart. PloS one 20110101
Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors. Fibrogenesis & tissue repair 20110101
Telmisartan and cardioprotection. Vascular health and risk management 20110101
Zofenopril and incidence of cough: a review of published and unpublished data. Therapeutics and clinical risk management 20110101
Combining antihypertensive and antihyperlipidemic agents - optimizing cardiovascular risk factor management. Integrated blood pressure control 20110101
Medical angioplasty - hope and expectations: an optimistic overview. Journal of family & community medicine 20110101
The polypill in the primary prevention of cardiovascular disease: cost-effectiveness in the Dutch population. BMJ open 20110101
Systematic drug repositioning based on clinical side-effects. PloS one 20110101
The case for an elderly targeted stroke management. Frontiers in neurology 20110101
TRC120038, a Novel Dual AT(1)/ET(A) Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats. International journal of hypertension 20110101
Critical review of cancer risk associated with angiotensin receptor blocker therapy. Vascular health and risk management 20110101
Benefits of once-daily therapies in the treatment of hypertension. Vascular health and risk management 20110101
Effect of ramipril therapy on abnormal left atrial appendage function. The Journal of international medical research 20110101
Thrombotic occlusion of all left coronary branches in a young woman with severe ulcerative colitis. ISRN cardiology 20110101
Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion. ISRN cardiology 20110101
Neurosurgery in an octogenarian with dementia. The Ulster medical journal 20110101
Optimal management of peripheral arterial disease for the non-specialist. The Ulster medical journal 20110101
Growth hormone deficiency, short stature, and juvenile rheumatoid arthritis in a patient with autoimmune polyglandular syndrome type 1: case report and brief review of the literature. ISRN endocrinology 20110101
Aggressive versus Low Dose Inhibition of the Renin-Angiotensin System for the Treatment of Microalbuminuria in Type 2 Diabetic Patients: A Pilot Study. ISRN endocrinology 20110101
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Pharmacological and nutritional treatment for McArdle disease (Glycogen Storage Disease type V). The Cochrane database of systematic reviews 20101208
Soybeans ameliolate diabetic nephropathy in rats. Evidence-based complementary and alternative medicine : eCAM 20101201
Comparative efficacy of aliskiren monotherapy and ramipril monotherapy in patients with stage 2 systolic hypertension: subgroup analysis of a double-blind, active comparator trial. Cardiovascular therapeutics 20101201
Spontaneous resolution of severe mitral regurgitation in a patient with a flail mitral valve. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20101201
Regression of target organ damage in children and adolescents with primary hypertension. Pediatric nephrology (Berlin, Germany) 20101201
Differences between zofenopril and ramipril, two ACE inhibitors, on cough induced by citric acid in guinea pigs: role of bradykinin and PGE2. Naunyn-Schmiedeberg's archives of pharmacology 20101201
Ramipril-like activity of Spondias mombin linn against no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart. Cardiovascular toxicology 20101201
Inhibition of chymase protects against diabetes-induced oxidative stress and renal dysfunction in hamsters. American journal of physiology. Renal physiology 20101201
Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits. Journal of cardiovascular pharmacology and therapeutics 20101201
Beyond ONTARGET: angiotensin-converting enzyme inhibition and angiotensin II receptor blockade in combination, a lesser evil in some? Diabetes, obesity & metabolism 20101201
Dual renin-angiotensin system blockade for patients with prosthesis-patient mismatch. The Annals of thoracic surgery 20101201
A novel analytical approach for reducing the consumption of organic solvents in the charge transfer-based spectrophotometric analysis: application in the analysis of certain antihypertensive drugs. Acta pharmaceutica (Zagreb, Croatia) 20101201
Triple Combination Therapy Using Metformin, Thiazolidinedione, and a GLP-1 Analog or DPP-IV Inhibitor in Patients with Type 2 Diabetes Mellitus. Korean diabetes journal 20101201
Simvastatin, sildenafil and their combination in monocrotaline induced pulmonary arterial hypertension. Korean circulation journal 20101201
Heart failure--concepts and significance. Birth of a prognostic model. Journal of medicine and life 20101115
Diagnosis of early myocarditis after respiratory or gastrointestinal tract viral infection: insights from cardiovascular magnetic resonance. Clinical research in cardiology : official journal of the German Cardiac Society 20101101
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Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients with type 2 diabetes and nephropathy. Diabetes care 20101101
The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus. Current cardiology reports 20101101
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database. Journal of hypertension 20101101
Antihypertensive efficacy and safety of olmesartan medoxomil and ramipril in elderly patients with mild to moderate essential hypertension: the ESPORT study. Journal of hypertension 20101101
Immobilization stress induces endothelial dysfunction by oxidative stress via the activation of the angiotensin II/its type I receptor pathway. Atherosclerosis 20101101
The cardiac renin-angiotensin system is responsible for high-salt diet-induced left ventricular hypertrophy in mice. European journal of heart failure 20101101
Effects of ethnicity on diabetes incidence and prevention: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabetic medicine : a journal of the British Diabetic Association 20101101
A case of acute myocarditis caused by pandemic (H1N1) 2009 influenza virus. Journal of the Formosan Medical Association = Taiwan yi zhi 20101101
Strategies for initial management of hypertension. The Indian journal of medical research 20101101
Congestive heart failure in Indians: how do we improve diagnosis & management? The Indian journal of medical research 20101101
Diabetes & coronary heart disease: current perspectives. The Indian journal of medical research 20101101
Aliskiren: a review of its use as monotherapy and as combination therapy in the management of hypertension. Drugs 20101022
CORD: COmparison of Recommended Doses of ace inhibitors and angiotensin II receptor blockers. International journal of cardiology 20101008
Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101001
Incidence, severity, and etiology of drug-induced acute pancreatitis. Digestive diseases and sciences 20101001
Efficacy of primary prevention interventions when fasting and postglucose dysglycemia coexist: analysis of the Indian Diabetes Prevention Programmes (IDPP-1 and IDPP-2). Diabetes care 20101001
Interactions among related genes of renin-angiotensin system associated with type 2 diabetes. Diabetes care 20101001
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. Diabetes care 20101001
Sitagliptin-induced hemolysis. Indian journal of pharmacology 20101001
Angiotensin converting enzyme gene polymorphism and influence of ACE inhibition. Indian journal of nephrology 20101001
Determination of pK(a) values of some antihypertensive drugs by liquid chromatography and simultaneous assay of lercanidipine and enalapril in their binary mixtures. Talanta 20100915
Aliskiren for geriatric lowering of systolic hypertension: a randomized controlled trial. Journal of human hypertension 20100901
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Cutting through the statistical fog: understanding and evaluating non-inferiority trials. International journal of clinical practice 20100901
Effectiveness, safety and cost of drug substitution in hypertension. British journal of clinical pharmacology 20100901
Diabetes and heart failure in patients with coronary disease: separating markers from mediators. Diabetes care 20100901
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Perspectives on the chronotherapy of hypertension based on the results of the MAPEC study. Chronobiology international 20100901
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ACE inhibition reduces infarction in normotensive but not hypertensive rats: correlation with cortical ACE activity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100801
The association of hemoglobin a1c with incident heart failure among people without diabetes: the atherosclerosis risk in communities study. Diabetes 20100801
Drug mechanisms to help in managing resistant hypertension in obesity. Current hypertension reports 20100801
Dual renin-angiotensin-aldosterone system blockade for diabetic kidney disease. Current diabetes reports 20100801
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Counterpoint: postprandial glucose levels are not a clinically important treatment target. Diabetes care 20100801
Epidemiology and risk factors of cerebral ischemia and ischemic heart diseases: similarities and differences. Current cardiology reviews 20100801
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Association of ADIPOQ genetic variants and plasma adiponectin isoforms with the risk of incident renal events in type 2 diabetes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701
Diuretic uptitration with half dose combined ACEI + ARB better decreases proteinuria than combined ACEI + ARB uptitration. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701
Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis. Diabetologia 20100701
Prediction of incident diabetic neuropathy using the monofilament examination: a 4-year prospective study. Diabetes care 20100701
Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway. Transplant immunology 20100701
Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis. American journal of nephrology 20100701
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Marfan syndrome and focal segmental glomerulosclerosis: a novel association. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100701
Effects of suboptimal doses of the AT1 receptor blocker, telmisartan, with the angiotensin-converting enzyme inhibitor, ramipril, on cerebral arterioles in spontaneously hypertensive rat. Journal of hypertension 20100701
Angiotensin-converting enzyme inhibitors and angioedema. Allergy, asthma & immunology research 20100701
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Anti-albuminuric efficacy of a combination of angiotensin converting enzyme inhibitor & angiotensin receptor blocker in type 1 DM with nephropathy. The Indian journal of medical research 20100701
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Glucose levels predict hospitalization for congestive heart failure in patients at high cardiovascular risk. Circulation 20070320
Trials that matter: rosiglitazone, ramipril, and the prevention of type 2 diabetes. Annals of internal medicine 20070320
Spectrophotometric and spectrofluorimetric methods for the determination of ramipril in its pure and dosage form. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070301
Interstitial remodeling in beta1-adrenergic receptor transgenic mice. Basic research in cardiology 20070301
Effects of ACE inhibition and beta-blockade on plasminogen activator inhibitor-1 and transforming growth factor-beta1 in carotid glomus and autonomic ganglia in hypertensive rats. American journal of hypertension 20070301
Manidipine plus delapril in patients with Type 2 diabetes and hypertension: reducing cardiovascular risk and end-organ damage. Expert review of cardiovascular therapy 20070301
Effect of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers on the frequency of post-cardiothoracic surgery atrial fibrillation. The Annals of pharmacotherapy 20070301
Pharmacological prevention of atherothrombotic events in patients with peripheral arterial disease. European journal of clinical investigation 20070301
The therapeutic effects of angiotensin-converting enzyme inhibitors in severe non-proliferative diabetic retinopathy. Korean journal of ophthalmology : KJO 20070301
Commentary. Brief communication: ramipril markedly improves walking ability in patients with peripheral arterial disease: a randomized trial. Perspectives in vascular surgery and endovascular therapy 20070301
Angiotensin-converting enzyme inhibitors and coronary heart disease prevention. Journal of the renin-angiotensin-aldosterone system : JRAAS 20070301
Antihypertensive and antioxidant action of amlodipine and vitamin C in patients of essential hypertension. Journal of clinical biochemistry and nutrition 20070301
Optimal timing for antihypertensive dosing: focus on valsartan. Therapeutics and clinical risk management 20070301
Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload. Journal of the American College of Cardiology 20070220
Investigation of the effect of a countywide protected learning time scheme on prescribing rates of ramipril: interrupted time series study. Family practice 20070201
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy? Endocrinology 20070201
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension (Dallas, Tex. : 1979) 20070201
Ramipril dose-dependently increases nitric oxide availability in the radial artery of essential hypertension patients. Journal of hypertension 20070201
Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose. British journal of anaesthesia 20070201
The DREAM Trial: using ramipril and rosiglitazone to prevent diabetes. Current diabetes reports 20070201
DREAM and ADOPT: rosiglitazone does what it says on the packet. Diabetic medicine : a journal of the British Diabetic Association 20070201
Effect of ramipril on the incidence of diabetes. The New England journal of medicine 20070201
Effect of ramipril on the incidence of diabetes. The New England journal of medicine 20070201
Effect of ramipril on the incidence of diabetes. The New England journal of medicine 20070201
Acute upper airway obstruction from acquired angioedema. Emergency medicine Australasia : EMA 20070201
[Fasciitis with eosinophilia: a possible causal role of angiotensin converting enzyme inhibitor]. Revue neurologique 20070201
Cardiovascular risk reduction by reversing endothelial dysfunction: ARBs, ACE inhibitors, or both? Expectations from the ONTARGET Trial Programme. Vascular health and risk management 20070201
Moexipril and left ventricular hypertrophy. Vascular health and risk management 20070201
Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial. Vascular health and risk management 20070201
Trandolapril/verapamil combination in hypertensive diabetic patients. Vascular health and risk management 20070201
Role of the vasodilator peptide angiotensin-(1-7) in cardiovascular drug therapy. Vascular health and risk management 20070201
Blood pressure normalization in a large population of hypertensive patients treated with perindopril/indapamide combination: results of the OPTIMAX trial. Vascular health and risk management 20070201
[The DREAM of diabetes prevention]. Revue medicale suisse 20070117
Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. American journal of physiology. Renal physiology 20070101
Therapeutic approach to FSGS in children. Pediatric nephrology (Berlin, Germany) 20070101
A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity. Journal of hypertension 20070101
Ramipril did not reduce incident diabetes in patients with impaired glycemic control. ACP journal club 20070101
A long-term 'memory' of HIF induction in response to chronic mild decreased oxygen after oxygen normalization. BMC cardiovascular disorders 20070101
Heterogeneity of human adipose blood flow. BMC clinical pharmacology 20070101
Chronic angiotensin II receptor blockade induces cardioprotection during ischemia by increased PKC-epsilon expression in the mouse heart. Journal of cardiovascular pharmacology 20070101
Ramipril in post-renal transplant erythrocytosis. Journal of nephrology 20070101
Comparison of higher dose of losartan treatment with losartan plus carvedilol and losartan plus ramipril in patients with glomerulonephritis and proteinuria. Renal failure 20070101
Propylthiouracil-induced vasculitis associated with ANCA: a case report. Renal failure 20070101
The efficacy of aliskiren, a direct renin inhibitor, in the treatment of hypertension. Reviews in cardiovascular medicine 20070101
[The best of epidemiology and cardiovascular prevention in 2006]. Archives des maladies du coeur et des vaisseaux 20070101
Takotsubo cardiomyopathy in a Caucasian Italian woman: case report. Cardiovascular ultrasound 20070101
Angiotensin-converting enzyme inhibitors in veterinary medicine. Current pharmaceutical design 20070101
The effect of ramipril therapy on cytokines and parameters of incipient diabetic nephropathy in patients with type 1 diabetes mellitus. The Journal of international medical research 20070101
Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation. Radiation oncology (London, England) 20070101
Ileostomy and ramipril-induced acute renal failure and shock. Heart & lung : the journal of critical care 20070101
Adjunctive treatment with moxonidine versus nitrendipine for hypertensive patients with advanced renal failure: a cost-effectiveness analysis. BMC nephrology 20070101
Aliskiren: a review of its use in the management of hypertension. Drugs 20070101
Diabetes prevention between RAAS inhibition and PPAR-gamma stimulation: the diabetes reduction assessment with ramipril and rosiglitazone medication (DREAM) trial. Journal of the cardiometabolic syndrome 20070101
Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes. Cardiovascular diabetology 20070101
Improving proteinuria, endothelial functions and asymmetric dimethylarginine levels in chronic kidney disease: ramipril versus valsartan. Blood purification 20070101
Clinical decision making and the expected value of information. Clinical trials (London, England) 20070101
[Anaphylactoid reaction in hemodyalisis: converting enzyme inhibitors interaction with no PAN 69 membrane]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101
Effect of ramipril therapy on cognitive functions in cases of mild to moderate essential hypertension. Indian journal of physiology and pharmacology 20070101
Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project. BMC public health 20070101
Comparison of persistence rates with angiotensin-converting enzyme inhibitors used in secondary and primary prevention of cardiovascular disease. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20070101
A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. BMC medical genetics 20070101
Telmisartan/hydrochlorothiazide versus valsartan/hydrochlorothiazide in obese hypertensive patients with type 2 diabetes: the SMOOTH study. Cardiovascular diabetology 20070101
Updated meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure. Clinical drug investigation 20070101
A perspective on telmisartan and cardiovascular risk. Reviews in cardiovascular medicine 20070101
Atrial fibrillation-related cardiomyopathy: a case report. Journal of medical case reports 20070101
Medicinal importance of grapefruit juice and its interaction with various drugs. Nutrition journal 20070101
Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting. Thrombosis journal 20070101
The Ontario printed educational message (OPEM) trial to narrow the evidence-practice gap with respect to prescribing practices of general and family physicians: a cluster randomized controlled trial, targeting the care of individuals with diabetes and hypertension in Ontario, Canada. Implementation science : IS 20070101
Effect of the angiotensin receptor blocker irbesartan on metabolic parameters in clinical practice: the DO-IT prospective observational study. Cardiovascular diabetology 20070101
Estimating the cost effectiveness of ramipril used for specific clinical indications: comparing the outcomes in four clinical trials with a common economic model. American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
Aliskiren: an oral renin inhibitor for the treatment of hypertension. Cardiology in review 20070101
The Functions of PPARs in Aging and Longevity. PPAR research 20070101
Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: a pooled analysis. Journal of the American Society of Hypertension : JASH 20070101
Telmisartan ramipril combination therapy reduces strokes and improves cardiac and renal protection in stroke prone spontaneously hypertensive rats. Journal of the American Society of Hypertension : JASH 20070101
Perindopril: the evidence of its therapeutic impact in hypertension. Core evidence 20070101
Tako-tsubo cardiomyopathy. The Libyan journal of medicine 20070101
Endothelial dysfunction, erectile dysfunction and phosphodiesterase 5 inhibitors. An update of the current data and future perspectives. Drug target insights 20070101
Nitric oxide and cardiovascular risk factors. Heart international 20070101
[Experiences of the DREAM trial]. Orvosi hetilap 20061231
Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects. Diabetologia 20061201
Why are mineralocorticoid receptor antagonists cardioprotective? Naunyn-Schmiedeberg's archives of pharmacology 20061201
Redefining the ACE-inhibitor dose-response relationship: substantial blood pressure lowering after massive doses. European journal of clinical pharmacology 20061201
Lichen planus pemphigoides associated with ramipril. International journal of dermatology 20061201
Influence of angiotensin converting enzyme inhibitor treatment on cardiac autonomic modulation in patients receiving haemodialysis. Nephrology (Carlton, Vic.) 20061201
Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data. Vascular health and risk management 20061201
Insulin resistance and plasma triglyceride level are differently related to cardiac hypertrophy and arterial stiffening in hypertensive subjects. Vascular health and risk management 20061201
Role of angiotensin II in retinal leukostasis in the diabetic rat. Experimental eye research 20061101
Synergistic protective effects of erythropoietin and olmesartan on ischemic stroke survival and post-stroke memory dysfunctions in the gerbil. Journal of hypertension 20061101
Cardiovascular outcomes in the African American Study of Kidney Disease and Hypertension (AASK) Trial. American journal of kidney diseases : the official journal of the National Kidney Foundation 20061101
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. International journal of clinical practice 20061101
Effects of blockade of the renin-angiotensin and endothelin systems on experimental bronchiolitis obliterans. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061101
Effect of ramipril on the incidence of diabetes. The New England journal of medicine 20061012
Angiotensin-converting-enzyme inhibitors for impaired glucose tolerance--is there still hope? The New England journal of medicine 20061012
Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy. International journal of cardiology 20061010
Different pathomechanisms of essential and obesity-associated hypertension in adolescents. Pediatric nephrology (Berlin, Germany) 20061001
Lessons from the African-American Study of Kidney Disease and Hypertension: an update. Current hypertension reports 20061001
Antihypertensive agents have different ability to modulate arterial pressure and heart rate variability in 2K1C rats. American journal of hypertension 20061001
[DREAM study: prevention of type 2 diabetes with ramipril and/or rosiglitazone in persons with dysglycaemia but no cardiovascular desease]. Revue medicale de Liege 20061001
DREAM study and its impact on India. The Journal of the Association of Physicians of India 20061001
Impact of ramipril on the circadian periodicity of acute myocardial infarction. The American journal of cardiology 20060915
Rationale and design of a study to evaluate management of proteinuria in patients at high risk for vascular events: the IMPROVE trial. Journal of human hypertension 20060901
Should angiotensin-converting enzyme-inhibitors be used to improve outcome in patients with coronary artery disease and 'preserved' left ventricular function? European heart journal 20060901
Angiotensin-converting enzyme inhibition reduces lipid deposits in myocardium and improves left ventricular function of obese zucker rats. Obesity (Silver Spring, Md.) 20060901
Vasopeptidase inhibition prevents target organ damage and improves survival in spontaneously hypertensive rats. Journal of the renin-angiotensin-aldosterone system : JRAAS 20060901
A review of telmisartan in the treatment of hypertension: blood pressure control in the early morning hours. Vascular health and risk management 20060901
Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease. Vascular health and risk management 20060901
Inhibition of angiotensin-converting enzyme reduces rat liver reperfusion injury via bradykinin-2-receptor. The Journal of surgical research 20060801
Lack of effect on coronary atherosclerotic disease biomarkers with modest dosing of an angiotensin-converting enzyme inhibitor, angiotensin II type-1 receptor blocker, and the combination. Coronary artery disease 20060801
Effects of angiotensin II on connexin 43 of VSMCs in arteriosclerosis. Journal of Zhejiang University. Science. B 20060801
[HOPE study]. Nihon rinsho. Japanese journal of clinical medicine 20060801
[Mechanism of Shenqi compound recipe anti-earlier diabetic artherosclerosis in GK rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801
Comparative impact of multiple biomarkers and N-Terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation 20060718
Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin. Blood 20060701
Angiotensin II inhibition reduces stress sensitivity of hypothalamo-pituitary-adrenal axis in spontaneously hypertensive rats. Endocrinology 20060701
Is ramipril really better than other angiotensin-converting enzyme inhibitors after acute myocardial infarction? The American journal of cardiology 20060701
The renal antifibrotic effects of angiotensin-converting enzyme inhibition involve bradykinin B2 receptor activation in angiotensin II-dependent hypertension. Journal of hypertension 20060701
Effects of ramipril on renal function during progressive overpacing-induced heart failure in dogs. American journal of veterinary research 20060701
Oxidative stress: a potentially important new marker in renal transplantation. The Journal of pediatrics 20060701
Ramipril treatment protects against nitrate-induced oxidative stress in eNOS-/- mice: An implication of the NADPH oxidase pathway. Journal of cardiovascular pharmacology 20060701
[In the framework of the 72nd Annual Meeting of the DKG (German CardiologySociety) in Mannheim presented: Ontarget-the until now largest study program on cardiovascular prevention in patients with hypertension]. MMW Fortschritte der Medizin 20060629
First LC-MS/MS electrospray ionization validated method for the quantification of perindopril and its metabolite perindoprilat in human plasma and its application to bioequivalence study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy. Diabetes research and clinical practice 20060601
Quality of life in the African American Study of Kidney Disease and Hypertension: effects of blood pressure management. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060601
Assessment of patients' and physicians' compliance to an ACE inhibitor treatment based on urinary N-acetyl Ser-Asp-Lys-Pro determination in the Noninsulin-Dependent Diabetes, Hypertension, Microalbuminuria, Proteinuria, Cardiovascular Events, and Ramipril (DIABHYCAR) study. Diabetes care 20060601
Can thiazolidinediones delay disease progression in type 2 diabetes? Current medical research and opinion 20060601
A review of Perindopril in the reduction of cardiovascular events. Vascular health and risk management 20060601
Valsartan in the treatment of heart attack survivors. Vascular health and risk management 20060601
High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system. Journal of cellular biochemistry 20060515
Captopril inhibits the oxidative modification of apolipoprotein B-100 caused by myeloperoxydase in a comparative in vitro assay of angiotensin converting enzyme inhibitors. European journal of pharmacology 20060510
Summaries for patients. Ramipril improves walking ability in patients with peripheral arterial disease. Annals of internal medicine 20060502
Brief communication: ramipril markedly improves walking ability in patients with peripheral arterial disease: a randomized trial. Annals of internal medicine 20060502
Risk constellations in patients with the metabolic syndrome: epidemiology, diagnosis, and treatment patterns. The American journal of medicine 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Lichenoid and granulomatous stomatitis: an entity or a non-specific inflammatory process? Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20060501
[Did a reform strategy in drug management improve doctors' prescribing habits in Montenegro: the example for the cardiovascular drugs]. Vojnosanitetski pregled 20060501
Differing effects of antihypertensive drugs on the incidence of diabetes mellitus among patients with hypertensive kidney disease. Archives of internal medicine 20060410
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril. Clinical research in cardiology : official journal of the German Cardiac Society 20060401
Endothelial dysfunction: how can one intervene at the beginning of the cardiovascular continuum? Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060401
Hypertension treatment and implications of recent cardiovascular outcome trials. Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060401
Effect of low-dose dual blockade of renin-angiotensin system on urinary TGF-beta in type 2 diabetic patients with advanced kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
Endogenous NO regulates plasminogen activator inhibitor-1 during angiotensin-converting enzyme inhibition. Hypertension (Dallas, Tex. : 1979) 20060301
Smart damping modulation of carotid wall energetics in human hypertension: effects of angiotensin-converting enzyme inhibition. Hypertension (Dallas, Tex. : 1979) 20060301
Microalbuminuria and tubular proteinuria as risk predictors of cardiovascular morbidity and mortality in essential hypertension: final results of a prospective long-term study (MARPLE Study)*. Journal of hypertension 20060301
Effect of ramipril on left ventricular mass in normotensive hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060301
Initiation of hypertension treatment with a fixed-dose combination or its monocomponents -- does it really matter? International journal of clinical practice 20060301
[Effects and mechanism of ShenQi compound recipe on inflammation maker in GK rats]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060301
Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker. Clinical journal of the American Society of Nephrology : CJASN 20060301
Interference from a glucuronide metabolite in the determination of ramipril and ramiprilat in human plasma and urine by gas chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis 20060224
High-performance liquid chromatography-mass spectrometric analysis of ramipril and its active metabolite ramiprilat in human serum: application to a pharmacokinetic study in the Chinese volunteers. Journal of pharmaceutical and biomedical analysis 20060213
Liquid chromatographic separation and UV determination of certain antihypertensive agents. Biomedical chromatography : BMC 20060201
Influence of commonly used drugs on the accuracy of cystatin C-derived glomerular filtration rate. Pediatric nephrology (Berlin, Germany) 20060201
Comparative bioavailability of two ramipril formulations after single-dose administration in healthy volunteers. International journal of clinical pharmacology and therapeutics 20060201
ACE inhibition in secondary prevention: are the results controversial? Clinical research in cardiology : official journal of the German Cardiac Society 20060201
Role of insulin-sensitizing property of telmisartan, a commercially available angiotensin II type 1 receptor blocker in preventing the development of atrial fibrillation. Medical hypotheses 20060101
Expression and response to angiotensin-converting enzyme inhibition of matrix metalloproteinases 2 and 9 in renal glomerular damage in young transgenic rats with renin-dependent hypertension. The Journal of pharmacology and experimental therapeutics 20060101
The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I). Journal of hypertension 20060101
Minimal change disease in association with fire coral (Millepora species) exposure. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060101
Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilat. BMC clinical pharmacology 20060101
Pharmacokinetics and pharmacodynamics of the vasopeptidase inhibitor AVE7688 in humans. Clinical pharmacology and therapeutics 20060101
Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate. Acta anaesthesiologica Scandinavica 20060101
A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring. American journal of hypertension 20060101
Successful heart failure therapy in mitochondrial disorder with noncompaction cardiomyopathy. The international journal of cardiovascular imaging 20060101
Anemia and chronic kidney disease are associated with poor outcomes in heart failure patients. BMC nephrology 20060101
Methods underpinning national clinical guidelines for hypertension: describing the evidence shortfall. BMC health services research 20060101
Revascularization and cardioprotective drug treatment in myocardial infarction patients: how do they impact on patients' survival when delivered as usual care. BMC cardiovascular disorders 20060101
Do patients receive recommended treatment of osteoporosis following hip fracture in primary care? BMC family practice 20060101
A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240]. Implementation science : IS 20060101
Pharmacokinetic and pharmacodynamic parameters of ramipril and ramiprilat in healthy dogs and dogs with reduced glomerular filtration rate. Journal of veterinary internal medicine 20060101
Differential effects of olmesartan and ramipril on inflammatory response after myocardial infarction in rats. Blood pressure 20060101
Effects of an interactive CD-program on 6 months readmission rate in patients with heart failure - a randomised, controlled trial [NCT00311194]. BMC cardiovascular disorders 20060101
A critical review of mathematical models and data used in diabetology. Biomedical engineering online 20060101
Arterial hypertension and stroke prevention: an update. Clinical and experimental hypertension (New York, N.Y. : 1993) 20060101
Gemcitabine in combination with EGF-Receptor antibody (Cetuximab) as a treatment of cholangiocarcinoma: a case report. BMC cancer 20060101
Essential mixed cryoglobulinemia type II. Clinical and experimental rheumatology 20060101
C-reactive protein (CRP)-lowering agents. Cardiovascular drug reviews 20060101
A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. 'ARAMIA'. Trials 20060101
ACE inhibitors and angiotensin II receptor blockers in IgA nephropathy with mild proteinuria: the ACEARB study. Journal of nephrology 20060101
The effect of ramipril on left ventricular mass, myocardial fibrosis, diastolic function, and plasma neurohormones in Maine Coon cats with familial hypertrophic cardiomyopathy without heart failure. Journal of veterinary internal medicine 20060101
Quantification of trandolapril and its metabolite trandolaprilat in human plasma by liquid chromatography/tandem mass spectrometry using solid-phase extraction. Rapid communications in mass spectrometry : RCM 20060101
Changes in heart failure medications in patients hospitalised and discharged. BMC family practice 20060101
Vasopeptidase inhibition normalizes blood pressure and restores endothelial function in renovascular hypertension. Kidney & blood pressure research 20060101
Chronic kidney disease care delivered by US family medicine and internal medicine trainees: results from an online survey. BMC medicine 20060101
Adherence to cardioprotective medications and mortality among patients with diabetes and ischemic heart disease. BMC cardiovascular disorders 20060101
Ramipril: a review of its use in preventing cardiovascular outcomes in high-risk patients. American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions. Chinese medicine 20060101
The question of whether diabetes and its cardiovascular risks can be prevented: a realistic DREAM? Blood pressure 20060101
Percutaneous resection of renal urothelial carcinoma using bipolar electrocautery. JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101
Antihypertensive and cardiovascular effects of combined blockade of renin-angiotensin system with ACE inhibitor and angiotensin II type 1 receptor blocker in hypertensive patients: A 24-week randomized controlled double-dummy trial. Heart international 20060101
Insulin-sensitizing and cardiovascular effects of the sodium-hydrogen exchange inhibitor, cariporide, in the JCR: LA-cp rat and db/db mouse. Journal of cardiovascular pharmacology 20051201
Cardioprotective activity of alcoholic extract of Tinospora cordifolia in ischemia-reperfusion induced myocardial infarction in rats. Biological & pharmaceutical bulletin 20051201
Do all patients with coronary artery disease benefit from angiotensin converting enzyme inhibitors? Journal of cardiovascular pharmacology and therapeutics 20051201
Tissue angiotensin-converting enzyme inhibitors: are they more effective than serum angiotensin-converting enzyme inhibitors? Clinical cardiology 20051201
[Effects of losartan, ramipril and their combination on left ventricular remodeling and function in spontaneous hypertensive rats]. Zhonghua yi xue za zhi 20051130
Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats. Neuroreport 20051128
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[Hypertension and diabetic nephropathy, a dangerous duo]. Medizinische Klinik (Munich, Germany : 1983) 20051115
Effects of combined inhibition of the Na+-H+ exchanger and angiotensin-converting enzyme in rats with congestive heart failure after myocardial infarction. British journal of pharmacology 20051101
Effects of an angiotensin-converting enzyme inhibitor (ramipril) on inflammatory markers in secondary prevention patients: RAICES Study. Coronary artery disease 20051101
Effects of angiotensin-converting enzyme inhibition on mitral regurgitation severity, left ventricular size, and functional capacity. American heart journal 20051101
Tolerability of ramipril 10 mg daily in high-risk cardiovascular patients in Taiwan: experience from Kaohsiung Medical University Chung-Ho Memorial Hospital. The Kaohsiung journal of medical sciences 20051101
[Hypertension, heart failure, myocardial infarction, secondary prevention: the role of perindopril]. Italian heart journal : official journal of the Italian Federation of Cardiology 20051101
Cardiovascular risk in patients with mild renal insufficiency: implications for the use of ACE inhibitors. Presse medicale (Paris, France : 1983) 20051022
Barriers to a trial of atherosclerosis prevention in systemic lupus erythematosus. Arthritis and rheumatism 20051015
Prolonged exposure to angiotensin-converting enzyme inhibitors during pregnancy. Fetal toxicity could be reversible. Canadian family physician Medecin de famille canadien 20051010
The African American Study of Kidney Disease: do these results indicate that 140/90 mm hg is good enough? Current hypertension reports 20051001
Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients. Diabetes 20051001
Effects of ramipril on arterial stiffness. Hypertension (Dallas, Tex. : 1979) 20051001
Angiotensin II receptor antagonists and heart failure: angiotensin-converting-enzyme inhibitors remain the first-line option. Prescrire international 20051001
[A patient with severe hyperkalaemia -- an emergency after RALES]. Deutsche medizinische Wochenschrift (1946) 20050909
The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis. Diabetologia 20050901
Combined effects of HMG-CoA-reductase inhibition and renin-angiotensin system blockade on experimental atherosclerosis. Atherosclerosis 20050901
Ramipril in the treatment of vascular diseases. Expert opinion on pharmacotherapy 20050901
The prevention of type 2 diabetes: what is the evidence? Minerva endocrinologica 20050901
Kinetic spectrophotometric method for the determination of ramipril in pharmaceutical formulations. AAPS PharmSciTech 20050901
Lercanidipine in hypertension. Vascular health and risk management 20050901
Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. Vascular health and risk management 20050901
Long-term effects of ramipril on cardiovascular events and on diabetes: results of the HOPE study extension. Circulation 20050830
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. Journal of the American Society of Nephrology : JASN 20050801
Angiotensin I-converting enzyme-dependent and neutral endopeptidase-dependent generation and degradation of angiotensin II contrarily modulate noradrenaline release: implications for vasopeptidase-inhibitor therapy? Journal of hypertension 20050801
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition. Diabetologia 20050801
An update of irbesartan and renin-angiotensin system blockade in diabetic nephropathy. Expert opinion on pharmacotherapy 20050801
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. European journal of heart failure 20050801
Cardiovascular events in hypertension trials of Angiotensin-converting enzyme inhibitors. Journal of clinical hypertension (Greenwich, Conn.) 20050801
[Effects of angiotensin receptor blocker and angiotensin-coverting enzyme inhibitor on vascular endothelial function in type 2 diabetic patients with atherosclerosis: a comparative study]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801
Validated ligand mapping of ACE active site. Journal of computer-aided molecular design 20050801
Ramipril induced polyserositis with pericardial tamponade and pleural effusion. International journal of cardiology 20050710
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Role of tissue kallikrein in the cardioprotective effects of ischemic and pharmacological preconditioning in myocardial ischemia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Blood pressure control, drug therapy, and kidney disease. Hypertension (Dallas, Tex. : 1979) 20050701
Renal failure following bowel cleansing with a sodium phosphate purgative. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701
Ramipril prevents extracellular matrix accumulation in cerebral microvessels. Neurological research 20050701
Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes. Hypertension (Dallas, Tex. : 1979) 20050601
Effect of the renin-angiotensin system or calcium channel blockade on the circadian variation of heart rate variability, blood pressure and circulating catecholamines in hypertensive patients. Journal of hypertension 20050601
Ramipril reduces large-artery stiffness in peripheral arterial disease and promotes elastogenic remodeling in cell culture. Hypertension (Dallas, Tex. : 1979) 20050601
Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus. The American journal of cardiology 20050601
[Association between angiotensin converting enzyme I/D polymorphism and high-sensitivity C-reactive protein in type 2 diabetic patients with atherosclerosis treated with ramipril]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Cost-effectiveness in Italy of preventive treatment with ramipril in patients at high risk of cardiovascular events. Current medical research and opinion 20050601
The comparative effects of telmisartan and ramipril on P-wave dispersion in hypertensive patients: a randomized clinical study. Clinical cardiology 20050601
Prevalence, clinical significance, and management of peripheral arterial disease in women: is there a role for postmenopausal hormone therapy? Vascular health and risk management 20050601
Have angiotensin receptor blockers lived up to expectations? The Canadian journal of cardiology 20050515
The renin angiotensin system as a therapeutic target to prevent diabetes and its complications. Cardiology clinics 20050501
Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. Journal of hypertension 20050501
Late recurrence of scleroderma renal crisis in a renal transplant recipient despite angiotensin II blockade. American journal of kidney diseases : the official journal of the National Kidney Foundation 20050501
Influence of the angiotensin converting enzyme inhibitor ramipril on high-sensitivity C-reactive protein (hs-CRP) in patients with documented atherosclerosis. Zeitschrift fur Kardiologie 20050501
The HOPE TIPS: the HOPE study translated into practices. Cardiovascular drugs and therapy 20050501
Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction. Life sciences 20050429
Stability of ramipril in the solvents of different pH. Journal of pharmaceutical and biomedical analysis 20050429
The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. Archives of internal medicine 20050425
Inhibition of angiotensin-converting enzyme and phosphodiesterase type 5 improves endothelial function in heart failure. Clinical science (London, England : 1979) 20050401
Managing the patient at risk for a second stroke. Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20050401
The cardiovascular continuum and renin-angiotensin-aldosterone system blockade. Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20050401
Role of echocardiography in assessing the mechanism and effect of ramipril on functional mitral regurgitation in dilated cardiomyopathy. Echocardiography (Mount Kisco, N.Y.) 20050401
The ONTARGET/TRANSCEND Trial Programme: baseline data. Acta diabetologica 20050401
LC-MS determination and bioavailability study of imidapril hydrochloride after the oral administration of imidapril tablets in human volunteers. Archives of pharmacal research 20050401
ACE inhibition reduces activity of the plasminogen/plasmin and MMP systems in the brain of spontaneous hypertensive stroke-prone rats. Neuroscience letters 20050316
Endothelin receptor blockade improves endothelial function in atherosclerotic patients on angiotensin converting enzyme inhibition. Journal of internal medicine 20050301
Benefits from angiotensin-converting enzyme inhibitor 'beyond blood pressure lowering': beyond blood pressure or beyond the brachial artery? Journal of hypertension 20050301
Transforming growth factor beta1 and additional renoprotective effect of combination ACE inhibitor and angiotensin II receptor blocker in hypertensive subjects with minor renal abnormalities: a 24-week randomized controlled trial. Journal of hypertension 20050301
Renoprotective therapy: is it blood pressure or albuminuria that matters? Lancet (London, England) 20050301
Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial. Lancet (London, England) 20050301
Serum potassium, cardiovascular risk, and effects of an ACE inhibitor: results of the HOPE study. Clinical nephrology 20050301
Efficacy and safet of pimobendan in canine heart failure caused by myxomatous mitral valve disease. The Journal of small animal practice 20050301
Pregnancy outcome following exposure to orlistat, ramipril, glimepiride in a woman with metabolic syndrome. Saudi medical journal 20050301
Renoprotective effect of early inhibition of the renin-angiotensin system in renal transplant recipients. Transplantation proceedings 20050301
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In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease. Vascular health and risk management 20050301
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vascular health and risk management 20050301
Differential associations between actual and expected GP practice prescribing rates for statins, ACE inhibitors, and beta-blockers: a cross-sectional study in England. Therapeutics and clinical risk management 20050301
Diuretic and enhanced sodium restriction results in improved antiproteinuric response to RAS blocking agents. Journal of the American Society of Nephrology : JASN 20050201
Myocardial infarction increases ACE2 expression in rat and humans. European heart journal 20050201
Isolated sarcoid granulomatous interstitial nephritis responding to infliximab therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation 20050201
Impact of cigarette smoking in high-risk patients participating in a clinical trial. A substudy from the Heart Outcomes Prevention Evaluation (HOPE) trial. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050201
Case-based study: from prediabetes to complications--opportunities for prevention. PLoS medicine 20050201
The cardioprotective effect of dual metallopeptidase inhibition: respective roles of endogenous kinins and natriuretic peptides. Canadian journal of physiology and pharmacology 20050201
Sirolimus and ACE-inhibitors: a note of caution. Transplantation 20050127
Combined effects of ramipril and angiotensin II receptor blocker TCV116 on rat congestive heart failure after myocardial infarction. Chinese medical journal 20050120
Comparison of angiotensin-converting enzyme inhibitors in the treatment of congestive heart failure. The American journal of cardiology 20050115
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Ramipril-induced agranulocytosis confirmed by a lymphocyte cytotoxicity test. The American journal of the medical sciences 20050101
Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives. American journal of hypertension 20050101
Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition. American journal of hypertension 20050101
Preventing type 2 diabetes mellitus. The Journal of the American Board of Family Practice 20050101
Blockade of the renin-angiotensin system increases plasma adiponectin levels in type-2 diabetic patients with proteinuria. Nephron. Clinical practice 20050101
A meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure. American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
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Pharmacologic treatment of chronic pediatric hypertension. Paediatric drugs 20050101
Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovascular diabetology 20050101
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Metabolic effect of telmisartan and losartan in hypertensive patients with metabolic syndrome. Cardiovascular diabetology 20050101
Determinants of persistence in hypertensive patients treated with irbesartan: results of a postmarketing survey. BMC cardiovascular disorders 20050101
Some fundamental and technical aspects of the quantitative analysis of pharmaceutical drugs by matrix-assisted laser desorption/ionization mass spectrometry. Rapid communications in mass spectrometry : RCM 20050101
Peripheral arterial disease: a high risk - but neglected - disease population. BMC cardiovascular disorders 20050101
Progression of kidney disease in type 2 diabetes - beyond blood pressure control: an observational study. BMC nephrology 20050101
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ACE inhibition lowers angiotensin-II-induced monocyte adhesion to HUVEC by reduction of p65 translocation and AT 1 expression. Journal of vascular research 20050101
The HOPE (Heart Outcomes Prevention Evaluation) Study and its consequences. Scandinavian journal of clinical and laboratory investigation. Supplementum 20050101
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Pre-clinical and clinical experience of telmisartan in cardiac remodelling. The Journal of international medical research 20050101
Ventricular and vascular remodelling effects of the angiotensin II receptor blocker telmisartan and/or the angiotensin-converting enzyme inhibitor ramipril in hypertensive patients. The Journal of international medical research 20050101
Rationale and design of the cardiac magnetic resonance imaging substudy of The ONTARGET Trial Programme. The Journal of international medical research 20050101
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Does the Angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism modify the response to ACE inhibitor therapy?--A systematic review. Current controlled trials in cardiovascular medicine 20050101
Effect of pre-operative angiotensin-converting enzyme inhibitors on haemodynamic parameters and vasoconstrictor requirements in patients undergoing off-pump coronary artery bypass surgery. The Journal of international medical research 20050101
Angiotensin inhibition or blockade for the treatment of patients with quiescent lupus nephritis and persistent proteinuria. Lupus 20050101
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Aliskiren in hypertension: evidence for its potential therapeutic value. Core evidence 20050101
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The PROGRESS trial three years later: HOPE trial may shed some light. BMJ (Clinical research ed.) 20041211
ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression. Biochemical and biophysical research communications 20041210
Manipulation of the renin angiotensin system in peripheral arterial disease. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20041201
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Identification of angiotensin converting enzyme 2 in the rodent retina. Current eye research 20041201
On-line assay of the S-enantiomers of enalapril, ramipril and pentopril using a sequential injection analysis/amperometric biosensor system. Journal of pharmaceutical and biomedical analysis 20041119
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The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes. Kidney international. Supplement 20041101
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Vascular effects of simvastatin combined with ramipril in hypercholesterolemic patients with coronary artery disease, compared with simvastatin alone: a randomized, double-blind, placebo-controlled, crossover study. Atherosclerosis 20041101
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Provision of cardiovascular protection by ACE inhibitors: a review of recent trials. Current medical research and opinion 20041001
Acute pancreatitis due to ramipril therapy. Postgraduate medical journal 20041001
A comparison of the efficacy and duration of action of telmisartan, amlodipine and ramipril in patients with confirmed ambulatory hypertension. Blood pressure monitoring 20041001
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Targeting insulin resistance and beta-cell dysfunction: the role of thiazolidinediones. Diabetes technology & therapeutics 20041001
Effect of lercanidipine compared with ramipril on albumin excretion rate in hypertensive Type 2 diabetic patients with microalbuminuria: DIAL study (diabete, ipertensione, albuminuria, lercanidipina). Diabetes, nutrition & metabolism 20041001
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Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial. Diabetologia 20040901
Extended follow-up of patients randomly assigned in the Angiotensin-converting enzyme inhibition Post-Revascularization Study (APRES). American heart journal 20040901
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Simvastatin combined with ramipril treatment in hypercholesterolemic patients. Hypertension (Dallas, Tex. : 1979) 20040801
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Old antihypertensives and new diabetes. Journal of hypertension 20040801
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The JNC 7 approach compared to conventional treatment in diabetic patients with hypertension: a double-blind trial of initial monotherapy vs. combination therapy. Journal of clinical hypertension (Greenwich, Conn.) 20040801
Mortality rates in elderly patients who take different angiotensin-converting enzyme inhibitors after acute myocardial infarction: a class effect? Annals of internal medicine 20040720
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Antifibrotic, nephroprotective potential of ACE inhibitor vs AT1 antagonist in a murine model of renal fibrosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
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Cardiac angiotensin is upregulated in the hearts of unstable angina patients. Circulation research 20040625
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Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats. Acta pharmacologica Sinica 20040601
Effect of ramipril on postrevascularization prevalence of angina and quality of life. International journal of cardiology 20040601
Comparative study of angiotensin converting enzyme inhibitor and calcium channel blocker in the treatment of steroid-resistant idiopathic nephrotic syndrome. The Journal of the Association of Physicians of India 20040601
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. Circulation 20040511
Angina pectoris prior to myocardial infarction protects against subsequent left ventricular remodeling. Journal of the American College of Cardiology 20040505
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NPHS2 mutation associated with recurrence of proteinuria after transplantation. Pediatric nephrology (Berlin, Germany) 20040501
The problem of underdosing of angiotensin-converting enzyme inhibitors is markedly overrated: results from a study of patients discharged from hospital after an acute myocardial infarction. European journal of clinical pharmacology 20040501
Ramipril in the treatment of hypertension and proteinuria in children with chronic kidney diseases. American journal of hypertension 20040501
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Fresh frozen plasma in the treatment of resistant angiotensin-converting enzyme inhibitor angioedema. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040501
Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery disease. Cardiovascular drugs and therapy 20040501
Losartan-ramipril combination treatment. The Journal of the Association of Physicians of India 20040501
The effects of candesartan and ramipril on adrenal catecholamine release in anaesthetized dogs. European journal of pharmacology 20040405
An unusual cause of exertional leg pain. Current sports medicine reports 20040401
Preventing type II diabetes mellitus. Journal of clinical pharmacology 20040401
Bradykinin and matrix metalloproteinases are involved the structural alterations of rat small resistance arteries with inhibition of ACE and NEP. Journal of hypertension 20040401
Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20040401
Ramipril treatment suppresses islet fibrosis in Otsuka Long-Evans Tokushima fatty rats. Biochemical and biophysical research communications 20040326
Selective imidazoline agonist moxonidine plus the ACE inhibitor ramipril in hypertensive patients with impaired insulin sensitivity: partners in a successful MARRIAGE? Current medical research and opinion 20040301
Combined blockade of AT1-receptors and ACE synergistically potentiates antihypertensive effects in SHR. Journal of hypertension 20040301
Effects of ACE inhibition and AT1-receptor blockade on haemodynamic responses to L-arginine in Type 1 diabetes. Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301
[Involvement of angiotensin II in pathogenesis of hypertension and target organ damage]. Nihon rinsho. Japanese journal of clinical medicine 20040301
[Hypertensive nephrosclerosis]. Nihon rinsho. Japanese journal of clinical medicine 20040301
Evaluation of efficacy and tolerability of Losartan and Ramipril combination in the management of hypertensive patients with associated diabetes mellitus in India (LORD Trial). The Journal of the Association of Physicians of India 20040301
Effects of low dose ramipril on cardiovascular and renal outcomes in patients with type 2 diabetes and raised excretion of urinary albumin: randomised, double blind, placebo controlled trial (the DIABHYCAR study). BMJ (Clinical research ed.) 20040227
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Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat. Radiation research 20040201
Dual inhibition of ACE and NEP provides greater cardioprotection in mice with heart failure. Journal of cardiac failure 20040201
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Angiotensin-converting enzyme inhibitors and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cardiac Syndrome X: role of superoxide dismutase activity. Circulation 20040106
Angiotensin II and the fibroproliferative response to acute lung injury. American journal of physiology. Lung cellular and molecular physiology 20040101
Angiotensin II-dependent increased expression of Na+-glucose cotransporter in hypertension. American journal of physiology. Renal physiology 20040101
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Impact of ramipril in patients with evidence of clinical or subclinical peripheral arterial disease. European heart journal 20040101
What have we learned from the current trials? The Medical clinics of North America 20040101
Cutaneous vasculitis secondary to ramipril. Journal of drugs in dermatology : JDD 20040101
Neurohumoral stimulation in type-2-diabetes as an emerging disease concept. Cardiovascular diabetology 20040101
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Evidence-based cardiovascular care in the community: a population-based cross-sectional study. BMC family practice 20040101
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Cost effectiveness of ramipril in patients at high risk for cardiovascular events : economic evaluation of the HOPE (Heart Outcomes Prevention Evaluation) study for Germany from the Statutory Health Insurance perspective. PharmacoEconomics 20040101
Impaired glucose metabolism in patients with heart failure: pathophysiology and possible treatment strategies. American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101
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The EUROPA trial. Lancet (London, England) 20031206
Combine EUROPA and HOPE. Lancet (London, England) 20031206
Infarct size limiting effect of apstatin alone and in combination with enalapril, lisinopril and ramipril in rats with experimental myocardial infarction. Pharmacological research 20031201
Relationship of electrocardiographic left ventricular hypertrophy to mortality and cardiovascular morbidity in high-risk patients. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20031201
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Differential regulation of renin and Cox-2 expression in the renal cortex of C57Bl/6 mice. Pflugers Archiv : European journal of physiology 20031101
Angiotensin-converting enzyme inhibitors and stroke prevention: what about the influence of atrial fibrillation and antithrombotic therapy? Stroke 20031101
Ramipril-associated hepatotoxicity. Archives of pathology & laboratory medicine 20031101
Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease. Archives of biochemistry and biophysics 20031101
Progression of renal insufficiency in type 2 diabetes with and without microalbuminuria: results of the Heart Outcomes and Prevention Evaluation (HOPE) randomized study. American journal of kidney diseases : the official journal of the National Kidney Foundation 20031101
Vasopeptidase inhibition prevents nephropathy in Zucker diabetic fatty rats. Cardiovascular research 20031101
Recommendations for the management of special populations: racial and ethnic populations. American journal of hypertension 20031101
The effects of dual blockade of the renin-angiotensin system on urinary protein and transforming growth factor-beta excretion in 2 groups of patients with IgA and diabetic nephropathy. Clinical nephrology 20031101
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Should all patients with coronary disease receive angiotensin-converting-enzyme inhibitors? Lancet (London, England) 20030906
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Collapsing glomerulopathy coexisting with membranous glomerulonephritis in native kidney biopsies: a report of 3 HIV-negative patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030901
Evolving rationale for angiotensin-converting enzyme inhibition in chronic heart failure. The Mount Sinai journal of medicine, New York 20030901
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Ramipril improves nitric oxide availability in hypertensive rats with failing hearts after myocardial infarction. Journal of the renin-angiotensin-aldosterone system : JRAAS 20030901
Effect of chronic treatment with the vasopeptidase inhibitor AVE 7688 and ramipril on endothelial function in atherogenic diet rabbits. Journal of the renin-angiotensin-aldosterone system : JRAAS 20030901
Comparison of cardioprotective effects using ramipril and DanShen for the treatment of acute myocardial infarction in rats. Life sciences 20030801
Ramipril prevents microtubular changes in proximal tubules from streptozotocin diabetic rats. Nephrology (Carlton, Vic.) 20030801
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Design and statistical aspects of the African American Study of Kidney Disease and Hypertension (AASK). Journal of the American Society of Nephrology : JASN 20030701
The rationale and design of the AASK cohort study. Journal of the American Society of Nephrology : JASN 20030701
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More than just hype. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030624
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More than just hype. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030624
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Maximal suppression of renin-angiotensin system in nonproliferative glomerulonephritis. Kidney international 20030601
Retarding progression of chronic renal disease: the neglected issue of residual proteinuria. Kidney international 20030601
Aldosterone receptor blockade improves left ventricular remodeling and increases ventricular fibrillation threshold in experimental heart failure. Cardiovascular research 20030601
Effects of diuretic treatment on cardiac and circulating RAS in chronic heart failure post-myocardial infarction in rats. European journal of heart failure 20030601
Aspirin alters arterial function in patients with chronic heart failure treated with ACE inhibitors: a dose-mediated deleterious effect. European journal of heart failure 20030601
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More hype than HOPE. Hypertension (Dallas, Tex. : 1979) 20030401
Parallel renal and extremity blood supply abnormalities in nonmodulation: responses to ACE inhibition. Hypertension (Dallas, Tex. : 1979) 20030401
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products. Journal of human hypertension 20030401
Initial findings of the AASK: African Americans with hypertensive kidney disease benefit from an ACE inhibitor. Cleveland Clinic journal of medicine 20030401
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Assessment of the effect of ramipril therapy on direct health care costs for first and recurrent strokes in high-risk cardiovascular patients using data from the Heart Outcomes Prevention Evaluation (HOPE) study. Clinical therapeutics 20030401
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General inhibition of renocortical cyclooxygenase-2 expression by the renin-angiotensin system. American journal of physiology. Renal physiology 20030301
The prevention of type 2 diabetes--lifestyle change or pharmacotherapy? A challenge for the 21st century. Diabetes research and clinical practice 20030301
Development of renal disease in people at high cardiovascular risk: results of the HOPE randomized study. Journal of the American Society of Nephrology : JASN 20030301
Development of congestive heart failure in type 2 diabetic patients with microalbuminuria or proteinuria: observations from the DIABHYCAR (type 2 DIABetes, Hypertension, CArdiovascular Events and Ramipril) study. Diabetes care 20030301
Metformin-induced hemolytic anemia in a patient with glucose-6- phosphate dehydrogenase deficiency. Diabetes care 20030301
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy. Hypertension (Dallas, Tex. : 1979) 20030301
Economic impact of ramipril on hospitalization of high-risk cardiovascular patients. The Annals of pharmacotherapy 20030301
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Pharmacoeconomic implications of large multicenter clinical trials. The Annals of pharmacotherapy 20030301
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Cost implications of the use of ramipril in high-risk patients based on the Heart Outcomes Prevention Evaluation (HOPE) study. Circulation 20030225
Best bang for the buck? Current hypertension reports 20030201
The effect of ramipril on albumin excretion in diabetes and hypertension: the role of increased lysosomal activity and decreased transforming growth factor-beta expression. Journal of hypertension 20030201
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Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome. Kidney international 20030201
Long-term treatment with ramipril attenuates renal osteopontin expression in diabetic rats. Kidney international 20030201
Renoprotection: clues from knockout models of rare diseases. Kidney international 20030201
The antiproteinuric effect of high-dose ramipril: still an open question. Kidney international 20030201
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Spotlight on ramipril in the prevention of cardiovascular outcomes. American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
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Left and right coronary circulation in left ventricular hypertrophy: effects of angiotensin converting enzyme inhibition. Circulation journal : official journal of the Japanese Circulation Society 20021201
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Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy. Diabetes 20021101
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Oxidative stress in kidney transplant patients with calcineurin inhibitor-induced hypertension: effect of ramipril. Journal of cardiovascular pharmacology 20021001
Effect of ACE-inhibitor ramiprilat and AT1-receptor antagonist candesartan on cardiac norepinephrine release: comparison between ischemic and nonischemic conditions. Journal of cardiovascular pharmacology 20021001
Acute antihypertrophic actions of bradykinin in the rat heart: importance of cyclic GMP. Hypertension (Dallas, Tex. : 1979) 20021001
Ramipril treatment alters Ca(2+) and K(+) channels in small mesenteric arteries from Wistar-Kyoto and spontaneously hypertensive rats. American journal of hypertension 20021001
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Vitamins, antioxidants and endothelial function in coronary artery disease. Cardiovascular drugs and therapy 20020901
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Preventing stroke with ramipril. Benefits were considerably overstated. BMJ (Clinical research ed.) 20020824
Preventing stroke with ramipril. Superiority of particular class of antihypertensive agent remains to be shown. BMJ (Clinical research ed.) 20020824
Preventing stroke with ramipril. Presentation of data is misleading. BMJ (Clinical research ed.) 20020824
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Effect of long-term therapy with ramipril in high-risk women. Journal of the American College of Cardiology 20020821
Chronic hydroxymethylglutaryl coenzyme a reductase inhibition and endothelial function of the normocholesterolemic rat: comparison with angiotensin-converting enzyme inhibition. Journal of cardiovascular pharmacology 20020801
Long-term angiotensin-converting enzyme inhibition with ramipril reduces thrombin generation in human hypertension. Clinical science (London, England : 1979) 20020801
Cost-effectiveness of the treatment of heart failure with ramipril: a Spanish analysis of the AIRE study. European journal of heart failure 20020801
Using ACE inhibitors appropriately. American family physician 20020801
Ramipril prior to thrombolysis attenuates the early increase of PAI-1 in patients with acute myocardial infarction. Thrombosis and haemostasis 20020801
Successful blood pressure control in the African American Study of Kidney Disease and Hypertension. Archives of internal medicine 20020722
Who is fooling us? Lancet (London, England) 20020706
Decreased susceptibility of cardiac function to hypoxia-reoxygenation in renin-angiotensinogen transgenic rats. American journal of physiology. Regulatory, integrative and comparative physiology 20020701
Angiotensin-converting enzyme inhibitors and diarrhea. Journal of clinical gastroenterology 20020701
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. Journal of hypertension 20020701
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Ramipril and cardiovascular risk reduction. Circulation 20020625
Blood pressure and cardiovascular risk in the HOPE study. Lancet (London, England) 20020615
Blood pressure and cardiovascular risk in the HOPE study. Lancet (London, England) 20020615
Effect of ramipril versus amlodipine on renal outcomes in hypertensive nephrosclerosis. Current hypertension reports 20020601
Angiotensin II feedback is a regulator of renocortical renin, COX-2, and nNOS expression. American journal of physiology. Regulatory, integrative and comparative physiology 20020601
Activity and functional significance of the renal kallikrein-kinin-system in polycystic kidney disease of the rat. Kidney international 20020601
The cost-effectiveness of ramipril in the treatment of patients at high risk of cardiovascular events: a Swedish sub-study to the HOPE study. Journal of internal medicine 20020601
Severe angioedema induced by angiotensin converting enzyme inhibitors: role of precipitating factors. The Journal of dermatology 20020601
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Class benefits of AT(1) antagonists in Type 2 diabetes with nephropathy. Expert opinion on pharmacotherapy 20020501
Ramipril improves hemodynamic recovery but not microvascular response to ischemia in spontaneously hypertensive rats. American journal of hypertension 20020501
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications. The Canadian journal of cardiology 20020501
[Diabetes mellitus and stroke]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020501
Blood pressure drug helps prevent stroke. Health news (Waltham, Mass.) 20020501
Spectrophotometric and AAS determination of ramipril and enalapril through ternary complex formation. Journal of pharmaceutical and biomedical analysis 20020415
Risk reduction for stroke and coronary events. Lancet (London, England) 20020406
Angiotensin II stimulates cyclooxygenase-2 mRNA expression in renal tissue from rats with kidney failure. American journal of physiology. Renal physiology 20020401
[Experience with Ramipril (Triatec(R)) in the treatment of glaucomatous neuropathy]. Journal francais d'ophtalmologie 20020401
ACE inhibition and atherogenesis. Canadian journal of physiology and pharmacology 20020401
The angiotensin-converting enzyme gene I/D polymorphism and heart rate variability following acute myocardial infarction. Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20020401
[Assessment of acute blood pressure variability during a stress test]. Annales de cardiologie et d'angeiologie 20020401
Preventing stroke. BMJ (Clinical research ed.) 20020323
Use of ramipril in preventing stroke: double blind randomised trial. BMJ (Clinical research ed.) 20020323
Renal protection by angiotensin II receptor antagonists in patients with type 2 diabetes. The Medical journal of Australia 20020318
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Role of renal nerves in stimulation of renin, COX-2, and nNOS in rat renal cortex during salt deficiency. American journal of physiology. Renal physiology 20020301
Ramipril administration to atherosclerotic mice reduces oxidized low-density lipoprotein uptake by their macrophages and blocks the progression of atherosclerosis. Atherosclerosis 20020301
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Acute and long-term effects of ACE inhibition on renal haemodynamics in glomerular and interstitial nephropathies. Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301
Blockade of endothelial enzymes: new therapeutic targets. Journal of human hypertension 20020301
Systemic immunosuppression fails to suppress cardiac cytokine induction in pressure overload hypertrophy in rats. Immunobiology 20020301
Induction of functional bradykinin b(1)-receptors in normotensive rats and mice under chronic Angiotensin-converting enzyme inhibitor treatment. Circulation 20020205
Effect of ramipril and furosemide treatment on interstitial remodeling in post-infarction heart failure rat hearts. Journal of molecular and cellular cardiology 20020201
Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension. American journal of hypertension 20020201
[The plasma levels of proinsulin and true insulin and the effects of ramipril in hypertension]. Zhonghua nei ke za zhi 20020201
Blood pressure drug may prevent diabetes in some people. Mayo Clinic health letter (English ed.) 20020201
'Preemptive strike' heart medications. A.C.E. inhibitors gain new ground as multi-purpose cardiac drugs. Heart advisor 20020201
Angiotensin II and trials of cardiovascular outcomes. The American journal of cardiology 20020124
From the HOPE to the ONTARGET and the TRANSCEND studies: challenges in improving prognosis. The American journal of cardiology 20020124
The 24-hour blood pressure pattern: does it have implications for morbidity and mortality? The American journal of cardiology 20020124
Comparative effects of estrogen and angiotensin-converting enzyme inhibition on plasminogen activator inhibitor-1 in healthy postmenopausal women. Circulation 20020122
Effect of ramipril and vitamin E on atherosclerosis. Circulation 20020115
Ramipril and risk of diabetes. JAMA 20020109
Ramipril and risk of diabetes. JAMA 20020109
Role of angiotensin II in dynamic renal blood flow autoregulation of the conscious dog. The Journal of physiology 20020101
Angiotensin AT(1) receptor signalling modulates reparative angiogenesis induced by limb ischaemia. British journal of pharmacology 20020101
Attenuating CV risk factors in patients with diabetes: clinical evidence to clinical practice. Diabetes, obesity & metabolism 20020101
What should the role of ACE inhibitors be in the treatment of diabetes? Lessons from HOPE and MICRO-HOPE. Diabetes, obesity & metabolism 20020101
Reducing the risk of stroke in diabetes: what have we learned that is new? Diabetes, obesity & metabolism 20020101
A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' study. Clinical genetics 20020101
Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clinical pharmacokinetics 20020101
Is there a clinically significant gender bias in post-myocardial infarction pharmacological management in the older (>60) population of a primary care practice? BMC family practice 20020101
Ramipril: a review of its use in the prevention of cardiovascular outcomes. Drugs 20020101
Results from the TIP (Tritace in Proteinuria) intensified monitoring project. Kidney & blood pressure research 20020101
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[Respiratory and renal functions and blood electrolytic composition in patients with pulmonary tuberculosis in the treatment of heart failure]. Problemy tuberkuleza 20020101
HOPE in PROGRESS--a tale of two trials: blood pressure reduction or drug mechanism? The American journal of geriatric cardiology 20020101
Inhibitors of the renin-angiotensin system reduce the rate of GFR decline and end-stage renal disease in patients with severe renal insufficiency. Journal of nephrology 20020101
Tolerability of 10 mg of ramipril in normotensive Indian patients. The National medical journal of India 20020101
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Intimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy. Cardiovascular diabetology 20020101
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Cardiovascular risk in patients with early renal insufficiency: implications for the use of ACE inhibitors. American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Changes in vasoconstrictive hormones, natriuretic peptides, and left ventricular remodeling soon after anterior myocardial infarction. American heart journal 20011201
ACE inhibitors to prevent end-stage renal disease: when to start and why possibly never to stop: a post hoc analysis of the REIN trial results. Ramipril Efficacy in Nephropathy. Journal of the American Society of Nephrology : JASN 20011201
Comparative effects of ramipril on ambulatory and office blood pressures: a HOPE Substudy. Hypertension (Dallas, Tex. : 1979) 20011201
Blood-pressure reduction and cardiovascular risk in HOPE study. Lancet (London, England) 20011201
[Renal failure and cardiovascular risk. Increased borderline serum creatinine--a warning sign?]. MMW Fortschritte der Medizin 20011129
Simvastatin reverses impaired regulation of renal oxygen consumption in congestive heart failure. American journal of physiology. Renal physiology 20011101
The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101
Prevention, protection, and the intrarenal renin-angiotensin systems. Seminars in nephrology 20011101
Sertraline-induced hypoglycemia. The Annals of pharmacotherapy 20011101
Effect of ramipril in a patient with glycogen storage disease type I and nephrotic-range proteinuria. Journal of inherited metabolic disease 20011101
[Late-appearing cholestatic icterus after a month of treatment with ticlopidine]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20011101
[Atherosclerosis. High ACE activity in plaque: risk of rupture!]. MMW Fortschritte der Medizin 20011025
Ramipril and the development of diabetes. JAMA 20011017
[Prediction, screening and treatment of renal complications of diabetes]. La Revue du praticien 20011015
[Type 2 diabetes and cardiovascular risk: lessons from therapeutic trials]. La Revue du praticien 20011015
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Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril. Circulation 20011002
Clinical trials report. The effect of Ramipril versus Amlodipine on renal outcomes in hypertension nephrosclerosis. Current hypertension reports 20011001
[Achieving vascular protection. ACE inhibitor lowers not only blood pressure]. MMW Fortschritte der Medizin 20010906
[Ramipril can do more. Halting progression of atherosclerosis]. MMW Fortschritte der Medizin 20010906
Can ACE inhibitor therapy prevent end-stage renal failure? The Medical journal of Australia 20010903
The Heart Outcomes Prevention Evaluation study: angiotensin-converting enzyme inhibitors: are their benefits a class effect or do individual agents differ? Current opinion in nephrology and hypertension 20010901
Inhibitors of bradykinin-inactivating enzymes decrease myocardial ischemia/reperfusion injury following 3 and 7 days of reperfusion. The Journal of pharmacology and experimental therapeutics 20010901
Apstatin, a selective inhibitor of aminopeptidase P, reduces myocardial infarct size by a kinin-dependent pathway. British journal of pharmacology 20010901
Enantioseparation of the anticoagulant drug phenprocoumon in capillary electrophoresis with UV and laser-induced fluorescence detection and application of the method to urine samples. Electrophoresis 20010901
What is the relevance of the HOPE study in general practice? International journal of clinical practice 20010901
What is the best treatment for slowing the progression to end-stage renal disease (ESRD) in African Americans with hypertensive nephropathy? The Journal of family practice 20010901
Inhibition of cyclooxygenase-2 attenuates urinary prostanoid excretion without affecting renal renin expression. Pflugers Archiv : European journal of physiology 20010901
Angiotensin II receptor blockers and cardiovascular outcomes: the evidence now and in the future. Journal of the renin-angiotensin-aldosterone system : JRAAS 20010901
[Diabetic nephropathy. Smoking also damages the kidney]. MMW Fortschritte der Medizin 20010823
Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation 20010821
Impaired angiotensin II regulation of renal C-type natriuretic peptide mRNA expression in experimental diabetes mellitus. Cardiovascular research 20010815
The HOPE study: comparison with other trials of secondary prevention. European heart journal 20010801
HOPE for patients with Type 2 diabetes: an application of the findings of the MICRO-HOPE substudy in a British hospital diabetes clinic. Diabetic medicine : a journal of the British Diabetic Association 20010801
[Effect of a non-antihypertensive dose of ramipril on the plasma and tissue renin-angiotensin system in 27 TGR (mRen2) rats]. Archives des maladies du coeur et des vaisseaux 20010801
Effects of ramipril on coronary events in high-risk persons: results of the Heart Outcomes Prevention Evaluation Study. Circulation 20010731
Simultaneous determination of hydrochlorothiazide and several inhibitors of angiotensin-converting enzyme by capillary electrophoresis. Journal of chromatography. A 20010727
Prevention of strokes. Current atherosclerosis reports 20010701
Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction. Cardiovascular research 20010701
Bradykinin metabolism in the isolated perfused rabbit heart. Journal of hypertension 20010701
Potentiation of kinin analogues by ramiprilat is exclusively related to their degradation. Hypertension (Dallas, Tex. : 1979) 20010701
Right atrial function in hypertensive patients: effects of antihypertensive therapy. Journal of human hypertension 20010701
Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade. Diabetologia 20010701
Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction. Journal of the American College of Cardiology 20010615
[Decreased platelet aggregation during angiotensin-converting enzyme inhibitor therapy. Results of a pilot study]. Deutsche medizinische Wochenschrift (1946) 20010615
Combined angiotensin II receptor antagonism and angiotensin-converting enzyme inhibition further attenuates postinfarction left ventricular remodeling. Circulation 20010612
Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. JAMA 20010606
Diminished cardioprotective response to inhibition of angiotensin-converting enzyme and angiotensin II type 1 receptor in B(2) kinin receptor gene knockout mice. Circulation research 20010525
Endothelial nitric oxide synthase plays an essential role in regulation of renal oxygen consumption by NO. American journal of physiology. Renal physiology 20010501
Cost effectiveness of ramipril treatment for cardiovascular risk reduction. Heart (British Cardiac Society) 20010501
Role of renocortical cyclooxygenase-2 for renal vascular resistance and macula densa control of renin secretion. Journal of the American Society of Nephrology : JASN 20010501
Reduction of ACE activity is insufficient to decrease microalbuminuria in normotensive patients with type 1 diabetes. Diabetes care 20010501
Why were the results of the Heart Outcomes Prevention Evaluation (HOPE) trial so astounding? The Canadian journal of cardiology 20010501
ACE inhibitor inhibits atherosclerosis. Harvard heart letter : from Harvard Medical School 20010501
Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial. Annals of internal medicine 20010417
The kidney in cardiovascular disease. Annals of internal medicine 20010417
Summaries for patients. Trial of a drug to decrease the risk for heart disease in patients with mild kidney failure. Annals of internal medicine 20010417
Recent clinical trial highlights in hypertension. Current hypertension reports 20010401
Beneficial effects of ramipril on left ventricular end-diastolic and end-systolic volume indexes after uncomplicated invasive revascularization are associated with a reduction in cardiac events in patients with moderately impaired left ventricular function and no clinical heart failure. Journal of the American College of Cardiology 20010401
Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed. Journal of cardiovascular pharmacology 20010401
Ask the doctor. Recently, I read that the ACE inhibitor ramipril is very good at preventing heart problems, particularly in people with diabetes. I'm diabetic, and for years I have been on a different ACE inhibitor (lisinopril). Should I be taking ramipril instead? Harvard heart letter : from Harvard Medical School 20010401
Use of 7-fluoro-4-nitrobenzo-2-oxo-1,3-diazole (NBD-F) for the determination of ramipril in tablets and spiked human plasma. Farmaco (Societa chimica italiana : 1989) 20010401
An ACE inhibitor to coronary patients: ramipril reduces mortality according to HOPE trial. Prescrire international 20010401
[Atherosclerosis. High dosage ACE inhibitor keeps event rate under control]. MMW Fortschritte der Medizin 20010329
Recovery of ventricular function after myocardial infarction in the reperfusion era: the healing and early afterload reducing therapy study. Annals of internal medicine 20010320
The Heart Outcomes Prevention Evaluation Study. Current cardiology reports 20010301
Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy. American journal of physiology. Heart and circulatory physiology 20010301
Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery. Clinical science (London, England : 1979) 20010301
Modulation of renal oxygen consumption by nitric oxide is impaired after development of congestive heart failure in dogs. Journal of cardiovascular pharmacology 20010301
Effects of angiotensin-converting enzyme inhibitor and angiotensin type 1 receptor antagonist in deoxycorticosterone acetate-salt hypertensive mice lacking Ren-2 gene. Hypertension (Dallas, Tex. : 1979) 20010301
What are 'tissue ACE inhibitors,' and should they be used instead of other ACE inhibitors? Cleveland Clinic journal of medicine 20010301
Management of asymptomatic left ventricular dysfunction. Cleveland Clinic journal of medicine 20010301
Effects of icatibant on the ramipril-induced decreased in renal lithium clearance in the rat. Naunyn-Schmiedeberg's archives of pharmacology 20010301
Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE). Circulation 20010220
Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: role of superoxide dismutase. Circulation 20010213
Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor. British journal of pharmacology 20010201
Regional wall stress predicts ventricular remodeling after anteroseptal myocardial infarction in the Healing and Early Afterload Reducing Trial (HEART): an echocardiography-based structural analysis. American heart journal 20010201
[ACE inhibition in patients with myocardial infarct and ventricular dysfunction: inappropriate application of therapy standards in patient samples]. Zeitschrift fur Kardiologie 20010201
Ramipril and aminoguanidine restore renal lysosomal processing in streptozotocin diabetic rats. Diabetologia 20010201
Intrarenal renin-angiotensin system contributes to tubular acidification adaptation following uninephrectomy. Experimental nephrology 20010101
Potential role of eNOS in the therapeutic control of myocardial oxygen consumption by ACE inhibitors and amlodipine. Cardiovascular research 20010101
Ramipril prolongs life and is cost effective in chronic proteinuric nephropathies. Kidney international 20010101
ACE inhibitor and AT1 antagonist blockade of deformation-induced gene expression in the rabbit jugular vein through B2 receptor activation. Arteriosclerosis, thrombosis, and vascular biology 20010101
Clinical, public health, and research implications of the Heart Outcomes Prevention Evaluation (HOPE) Study. European heart journal 20010101
Renal and vascular injury induced by exogenous angiotensin II is AT1 receptor-dependent. Nephron 20010101
A stability-indicating LC method for the simultaneous determination of ramipril and hydrochlorothiazide in dosage forms. Journal of pharmaceutical and biomedical analysis 20010101
Voltammetric determination of benazepril and ramipril in dosage forms and biological fluids through nitrosation. Journal of AOAC International 20010101
Hypertensive African Americans with kidney disease should seek advice from doctor about blood pressure medication. Ethnicity & disease 20010101
Significance of exaggerated natriuresis after angiotensin AT1 receptor blockade or angiotensin- converting enzyme inhibition in obese Zucker rats. Clinical and experimental pharmacology & physiology 20010101
[Severe hypoglycemia secondary to angiotensin-converting-enzyme inhibitors in the absence of diabetes mellitus. Report of a case]. Gaceta medica de Mexico 20010101
Differential regulation of cathepsin B and prorenin gene expression in renal juxtaglomerular cells. Kidney & blood pressure research 20010101
[Therapeutic perspectives: association of ACE inhibitors and angiotensin receptor blockers]. La Clinica terapeutica 20010101
Cost effectiveness of ramipril in patients with non-diabetic nephropathy and hypertension: economic evaluation of Ramipril Efficacy in Nephropathy (REIN) Study for Germany from the perspective of statutory health insurance. PharmacoEconomics 20010101
Study at up to 700 sites will build on landmark HOPE trial. Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101
The African American Study of Kidney Disease and Hypertension (AASK): new findings. Journal of clinical hypertension (Greenwich, Conn.) 20010101
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