200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 87081-36-5
87081-36-5 | Leptomycin A
CAS No: 87081-36-5 Catalog No: AG004MVE MDL No:
Product Description
Catalog Number:
AG004MVE
Chemical Name:
Leptomycin A
CAS Number:
87081-36-5
Molecular Formula:
C32H46O6
Molecular Weight:
526.7040
IUPAC Name:
(2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid
InChI:
InChI=1S/C32H46O6/c1-20(16-22(3)12-14-28-24(5)13-15-30(35)38-28)10-9-11-21(2)17-25(6)31(36)27(8)32(37)26(7)18-23(4)19-29(33)34/h9,11-17,19-20,24-28,32,37H,10,18H2,1-8H3,(H,33,34)/b11-9+,14-12+,21-17+,22-16+,23-19+
InChI Key:
QECBVZBMGUAZDL-DLWOFZAMSA-N
SMILES:
CC(=CC(C(=O)C(C(C(CC(=CC(=O)O)C)C)O)C)C)C=CCC(C=C(C=CC1OC(=O)C=CC1C)C)C
NSC Number:
369326
Properties
Complexity:
1010
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
5
Exact Mass:
526.329g/mol
Formal Charge:
0
Heavy Atom Count:
38
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
526.714g/mol
Monoisotopic Mass:
526.329g/mol
Rotatable Bond Count:
14
Topological Polar Surface Area:
101A^2
Undefined Atom Stereocenter Count:
7
Undefined Bond Stereocenter Count:
0
XLogP3:
7.4
Literature
| Title | Journal |
|---|---|
| ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase. | Biochimica et biophysica acta 20100201 |
| Total synthesis of callystatin a by titanium-mediated reductive alkyne-alkyne cross-coupling. | Angewandte Chemie (International ed. in English) 20080101 |
| The leptomycin gene cluster and its heterologous expression in Streptomyces lividans. | The Journal of antibiotics 20051001 |
| Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST). | The Journal of biological chemistry 20020405 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.