200,000+ products from a single source!
sales@angenechem.com
86-22-6 | Brompheniramine
CAS No: 86-22-6 Catalog No: AG004NGX MDL No:
Product Description
Catalog Number:
AG004NGX
Chemical Name:
Brompheniramine
CAS Number:
86-22-6
Molecular Formula:
C16H19BrN2
Molecular Weight:
319.2395
IUPAC Name:
3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
InChI:
InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
InChI Key:
ZDIGNSYAACHWNL-UHFFFAOYSA-N
SMILES:
CN(CCC(c1ccccn1)c1ccc(cc1)Br)C
EC Number:
201-657-8
Properties
Complexity:
249
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
318.073g/mol
Formal Charge:
0
Heavy Atom Count:
19
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
319.246g/mol
Monoisotopic Mass:
318.073g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
16.1A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
XLogP3:
3.5
Literature
| Title | Journal |
|---|---|
| Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. | Chemical research in toxicology 20170515 |
| Cross-sectional microhardness of bovine enamel subjected to three paediatric liquid oral medicines: an in vitro study. | European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 20121001 |
| Complementary fluorescence and phosphorescence study of the interaction of brompheniramine with human serum albumin. | The journal of physical chemistry. B 20120621 |
| Chemometric evaluation of brompheniramine-tannate complexes. | Journal of pharmaceutical sciences 20120401 |
| pH-dependent complexation of histamine H1 receptor antagonists and human serum albumin studied by UV resonance Raman spectroscopy. | The journal of physical chemistry. B 20120329 |
| Immunoassay screening of diphenhydramine (Benadryl®) in urine and blood using a newly developed assay. | Journal of analytical toxicology 20120301 |
| Tannate complexes of antihistaminic drug: sustained release and taste masking approaches. | International journal of pharmaceutics 20120117 |
| Analytical characterization and rapid determination of 2-(diphenylmethyl)pyrrolidine in blood and application to an internet product. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201 |
| Synthesis of imprinted beads by aqueous suspension polymerisation for chiral recognition of antihistamines. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115 |
| Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
| In vitro alterations in dental enamel exposed to acidic medicines. | International journal of paediatric dentistry 20110301 |
| Modulation of metabolic activity of phagocytes by antihistamines. | Interdisciplinary toxicology 20110301 |
| Antidepressants: From MAOIs to SSRIs and more. | Indian journal of psychiatry 20110101 |
| Commonly prescribed medications and potential false-positive urine drug screens. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100815 |
| Determination of chlorpheniramine in human plasma by HPLC-ESI-MS/MS: application to a dexchlorpheniramine comparative bioavailability study. | Biomedical chromatography : BMC 20100701 |
| Trace determination of pharmaceuticals and other wastewater-derived micropollutants by solid phase extraction and gas chromatography/mass spectrometry. | Journal of chromatography. A 20100122 |
| Arvid Carlsson, and the story of dopamine. | Indian journal of psychiatry 20100101 |
| Treatment of congestion in upper respiratory diseases. | International journal of general medicine 20100101 |
| Halogenation effects of pheniramines on the complexation with beta-cyclodextrin. | Journal of pharmaceutical and biomedical analysis 20091015 |
| Comparison of chiral separation of basic drugs in capillary electrophoresis and liquid chromatography using neutral and negatively charged cyclodextrins. | Analytica chimica acta 20090710 |
| Protective effect of pheniramines against mesenteric ischaemia/reperfusion-induced injury. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090401 |
| Pheniramines and oxidative burst of blood phagocytes during ischaemia/reperfusion. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090401 |
| Enantioseparation of a novel 'click' chemistry derived native beta-cyclodextrin chiral stationary phase for high-performance liquid chromatography. | Journal of chromatography. A 20090320 |
| A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation. | PloS one 20090101 |
| Acute cough: a diagnostic and therapeutic challenge. | Cough (London, England) 20090101 |
| H1-antihistamines and oxidative burst of professional phagocytes. | Neuro endocrinology letters 20090101 |
| Transient receptor potential vanilloid-1-mediated calcium responses are inhibited by the alkylamine antihistamines dexbrompheniramine and chlorpheniramine. | Experimental lung research 20081201 |
| Drug-liposome distribution phenomena studied by capillary electrophoresis-frontal analysis. | Electrophoresis 20080801 |
| Cough and cold medication use by US children, 1999-2006: results from the slone survey. | Pediatrics 20080801 |
| Surface degradation of composite resins by acidic medicines and pH-cycling. | Journal of applied oral science : revista FOB 20080801 |
| Potentialities of ITP-CZE method with diode array detection for enantiomeric purity control of dexbrompheniramine in pharmaceuticals. | Journal of pharmaceutical and biomedical analysis 20080414 |
| Uniformly sized molecularly imprinted polymers for d-chlorpheniramine: influence of a porogen on their morphology and enantioselectivity. | Journal of pharmaceutical and biomedical analysis 20080414 |
| The effect of achiral calixarenes on chiral separation of propranolol-HCl and brompheniramine maleate in capillary electrophoresis using cyclodextrin as chiral selector. | Die Pharmazie 20080401 |
| Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656. | Journal of applied toxicology : JAT 20080301 |
| Indirect fluorescent determination of selected nitro-aromatic and pharmaceutical compounds via UV-photolysis of 2-phenylbenzimidazole-5-sulfonate. | Talanta 20080215 |
| Possibilities of column coupling electrophoresis provided with a fiber-based diode array detection in enantioselective analysis of drugs in pharmaceutical and clinical samples. | Journal of chromatography. A 20080125 |
| Evaluation of enantioselective binding of antihistamines to human serum albumin by ACE. | Electrophoresis 20070801 |
| Evaluation of enantioselective binding of basic drugs to plasma by ACE. | Electrophoresis 20070801 |
| Enantiomeric quality control of antihistamines in pharmaceuticals by affinity electrokinetic chromatography with human serum albumin as chiral selector. | Analytica chimica acta 20070605 |
| First-generation H1 antihistamines found in pilot fatalities of civil aviation accidents, 1990-2005. | Aviation, space, and environmental medicine 20070501 |
| Characterization of antihistamine-human serum protein interactions by capillary electrophoresis. | Journal of chromatography. A 20070420 |
| Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children. | Journal of forensic sciences 20070301 |
| Medication administered to children from 0 to 7.5 years in the Avon Longitudinal Study of Parents and Children (ALSPAC). | European journal of clinical pharmacology 20070201 |
| Electrophysiological effects of brompheniramine on cardiac ion channels and action potential. | Pharmacological research 20061201 |
| Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine. | Neuro endocrinology letters 20061201 |
| Optimization by factorial design of a capillary zone electrophoresis method for the simultaneous separation of antihistamines. | Analytical biochemistry 20060501 |
| Antiradical effects of antihistamines in human blood. Structure-activity relationship. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401 |
| Role of chemical structure in stereoselective recognition of beta-blockers and H1-antihistamines by human serum transferrin in capillary zone electrophoresis. | Electrophoresis 20060401 |
| Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20060213 |
| The combined luminol/isoluminol chemiluminescence method for differentiating between extracellular and intracellular oxidant production by neutrophils. | Redox report : communications in free radical research 20060101 |
| Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death. | Journal of analytical toxicology 20051001 |
| Nimesulide-induced fixed drug eruption. | Allergologia et immunopathologia 20050101 |
| Laboratory exposures to staphylococcal enterotoxin B. | Emerging infectious diseases 20040901 |
| Retentivity and enantioselectivity of uniformly sized molecularly imprinted polymers for d-chlorpheniramine and -brompheniramine in hydro-organic mobile phases. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040505 |
| Fatal cold medication intoxication in an infant. | Journal of analytical toxicology 20031001 |
| Spermine-induced negative inotropic effect in isolated rat heart, is mediated through the release of ATP. | Biochemical pharmacology 20030701 |
| First do no harm: managing antihistamine impairment in patients with allergic rhinitis. | The Journal of allergy and clinical immunology 20030501 |
| Antihistamines in the treatment of dermatitis. | Journal of cutaneous medicine and surgery 20030101 |
| Update on medical treatment of ejaculatory disorders. | International journal of andrology 20021201 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Involvement of calmodulin inhibition in analgesia induced with low doses of intrathecal trifluoperazine. | Japanese journal of pharmacology 20020201 |
| Toxicity of over-the-counter cough and cold medications. | Pediatrics 20010901 |
| pH-independent large-volume sample stacking of positive or negative analytes in capillary electrophoresis. | Electrophoresis 20010101 |
| Withdrawal symptoms after discontinuation of long-acting brompheniramine maleate. | The British journal of dermatology 19941201 |
| Cardiomyopathy induced by phenylpropanolamine. | The Journal of pediatrics 19931101 |
| [Antimycobacterial antihistaminics]. | Archiv der Pharmazie 19890801 |
| Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines). | Clinical pharmacokinetics 19850101 |
| [Adverse effects and zimelidine therapy. Headache, muscle pain and liver involvement--a new disease entity in zimelidine therapy]. | Lakartidningen 19830105 |
| Severe headache and disturbed liver function during treatment with zimelidine. | British medical journal (Clinical research ed.) 19821113 |
| Severe headache and disturbed liver function during treatment with zimelidine. | British medical journal (Clinical research ed.) 19821009 |
| An open trial of zimelidine in patients with endogenous depression. | International pharmacopsychiatry 19820101 |
| Dystonic reactions to Dimotapp elixir. | The Journal of the Royal College of General Practitioners 19810401 |
| Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism. | Journal of neural transmission 19810101 |
| Event recording in a clinical trial of a new medicine. | British medical journal 19800503 |
| Cardiovascular effects of amitriptyline, mianserin and zimelidine in depressed patients. | Progress in neuro-psychopharmacology 19800101 |
| Phenylpropanolamine and mental disturbances. | Lancet (London, England) 19791201 |
| Oral facial dyskinesia accociated with prolonged use of antihistaminic decongestants. | The New England journal of medicine 19750904 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.