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84611-23-4 | Erdosteine
CAS No: 84611-23-4 Catalog No: AG003PY1 MDL No:MFCD00867664
Product Description
Catalog Number:
AG003PY1
Chemical Name:
Erdosteine
CAS Number:
84611-23-4
Molecular Formula:
C8H11NO4S2
Molecular Weight:
249.3072
MDL Number:
MFCD00867664
SMILES:
O=C(NC1CCSC1=O)CSCC(=O)O
Literature
| Title | Journal |
|---|---|
| Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins. | Toxicology and applied pharmacology 20151015 |
| Effects of erdosteine on cyclosporin-A-induced nephrotoxicity. | Human & experimental toxicology 20120601 |
| Effects of erdosteine on hemostasis: an experimental study. | Human & experimental toxicology 20120601 |
| Antioxidant pharmacological therapies for COPD. | Current opinion in pharmacology 20120601 |
| Pharmacological antioxidant strategies as therapeutic interventions for COPD. | Biochimica et biophysica acta 20120501 |
| Is intratympanic injection of erdosteine protective against cisplatin-induced ototoxicity? | Neurotoxicity research 20120401 |
| Protective effect of erdosteine against cisplatin-induced ototoxicity in a guinea pig model. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20120401 |
| Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats. | Molecular vision 20120101 |
| Severe drug hypersensitivity induced by erdosteine and doxofylline as confirmed by patch and lymphocyte transformation tests: a case report. | Journal of investigational allergology & clinical immunology 20120101 |
| Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models. | Oxidative medicine and cellular longevity 20120101 |
| Dual effects of erdosteine on hemostasis via its different metabolites in young rats. | Human & experimental toxicology 20111001 |
| Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication. | Human & experimental toxicology 20110901 |
| The protective effect of erdosteine on radiocontrast induced nephrotoxicity in rats. | Environmental toxicology 20110801 |
| [ Erdosteine (Mucodox), oral administration]. | Journal de pharmacie de Belgique 20110601 |
| Protective effects of erdosteine on amikacin induced visual evoked potentials and lipid peroxidation alterations. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401 |
| Effects of erdosteine on cyclosporine-A-induced hepatotoxicity in rats. | Drug and chemical toxicology 20110101 |
| Erdosteine affects eicosanoid production in COPD. | International journal of clinical pharmacology and therapeutics 20110101 |
| Prevention of pulmonary complications of pneumoperitoneum in rats. | Journal of cardiothoracic surgery 20110101 |
| Doxorubicin induced nephrotoxicity: protective effect of nicotinamide. | International journal of cell biology 20110101 |
| Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats. | BMC complementary and alternative medicine 20110101 |
| Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. | Arzneimittel-Forschung 20110101 |
| Effects of sulphurous water on human neutrophil elastase release. | Therapeutic advances in respiratory disease 20101201 |
| Combination antioxidant effect of α-tocoferol and erdosteine in ischemia-reperfusion injury in rat model. | International urology and nephrology 20100901 |
| Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice. | Toxicology and industrial health 20100801 |
| Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20100701 |
| Effect of the mucolytic erdosteine on the success rate of PPI-based first-line triple therapy for Helicobacter pylori eradication: a prospective, double-blind, randomized, placebo-controlled study. | Scandinavian journal of gastroenterology 20100601 |
| The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: a meta-analysis of individual patient data. | Pulmonary pharmacology & therapeutics 20100401 |
| Effectiveness of erdosteine, a second generation mucolytic agent, in children with acute rhinosinusitis: a randomized, placebo controlled, double-blinded clinical study. | Acta paediatrica (Oslo, Norway : 1992) 20100401 |
| Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. | Journal of the National Cancer Institute 20100106 |
| Erdosteine in renal ischemia-reperfusion injury: an experimental study in pigs. | The Journal of veterinary medical science 20100101 |
| Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis. | Respiratory research 20100101 |
| Free radical scavenging activity of erdosteine metabolite I investigated by electron paramagnetic resonance spectroscopy. | Pharmacology 20100101 |
| Ambroxol - Resurgence of an old molecule as an anti-inflammatory agent in chronic obstructive airway diseases. | Lung India : official organ of Indian Chest Society 20100101 |
| Association between lung function and exacerbation frequency in patients with COPD. | International journal of chronic obstructive pulmonary disease 20100101 |
| Doxorubicin toxicity can be ameliorated during antioxidant L-carnitine supplementation. | Oxidative medicine and cellular longevity 20100101 |
| Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity. | Interdisciplinary toxicology 20091201 |
| The protective effect of erdosteine on vancomycin-induced pancreatic damage in rats. | Molecular and cellular biochemistry 20091101 |
| Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. | The Journal of surgical research 20090801 |
| Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine. | Journal of gastroenterology and hepatology 20090401 |
| Erdosteine modulates radiocontrast-induced hepatotoxicity in rat. | Cell biochemistry and function 20090401 |
| Erdosteine: its relevance in COPD treatment. | Expert opinion on drug metabolism & toxicology 20090301 |
| The protective effect of erdosteine on short-term global brain ischemia/reperfusion injury in rats. | Progress in neuro-psychopharmacology & biological psychiatry 20090201 |
| Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. | Molecular aspects of medicine 20090101 |
| [Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin]. | Tuberkuloz ve toraks 20090101 |
| Raft of results energizes researchers. | IAVI report : newsletter on international AIDS vaccine research 20090101 |
| Simultaneous estimation of Cefixime and Erdosteine in capsule dosage form by spectrophotometric method. | Hindustan antibiotics bulletin 20090101 |
| Antioxidant therapeutic advances in COPD. | Therapeutic advances in respiratory disease 20081201 |
| The role for S-carboxymethylcysteine (carbocisteine) in the management of chronic obstructive pulmonary disease. | International journal of chronic obstructive pulmonary disease 20081201 |
| Erdosteine for COPD exacerbations. | Drug and therapeutics bulletin 20081001 |
| Erdosteine enhances airway response to salbutamol in patients with mild-to-moderate COPD. | Therapeutic advances in respiratory disease 20081001 |
| Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats. | Toxicology and industrial health 20080901 |
| The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of hippocampal neural cells. | Journal of cellular biochemistry 20080801 |
| Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats. | Toxicologic pathology 20080701 |
| High-throughput determination of fudosteine in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080501 |
| The effects of erdosteine on lung injury induced by the ischemia-reperfusion of the hind-limbs in rats. | The Journal of surgical research 20080401 |
| Antioxidant effect of sulphurous thermal water on human neutrophil bursts: chemiluminescence evaluation. | Respiration; international review of thoracic diseases 20080101 |
| Changes in blood ROS, e-NO, and some pro-inflammatory mediators in bronchial secretions following erdosteine or placebo: a controlled study in current smokers with mild COPD. | Pulmonary pharmacology & therapeutics 20080101 |
| Renoprotective effect of erdosteine in rats against gentamicin nephrotoxicity: a comparison of 99mTc-DMSA uptake with biochemical studies. | Molecular and cellular biochemistry 20080101 |
| Erdosteine: antitussive and anti-inflammatory effects. | Lung 20080101 |
| [Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin]. | Tuberkuloz ve toraks 20080101 |
| Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression. | Journal of inflammation (London, England) 20080101 |
| Antioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin. | BMC cancer 20080101 |
| Antioxidant systems and oxidative stress in the testes. | Oxidative medicine and cellular longevity 20080101 |
| Pharmacology and clinical efficacy of erdosteine in chronic obstructive pulmonary disease. | Expert review of respiratory medicine 20071201 |
| The protective effect of erdosteine against cyclosporine A-induced cardiotoxicity in rats. | Toxicology 20070924 |
| Erdosteine prevents colonic inflammation through its antioxidant and free radical scavenging activities. | Digestive diseases and sciences 20070901 |
| Mucoactive agents for airway mucus hypersecretory diseases. | Respiratory care 20070901 |
| Effectiveness of erdosteine in elderly patients with bronchiectasis and hypersecretion: a 15-day, prospective, parallel, open-label, pilot study. | Clinical therapeutics 20070901 |
| Future therapeutic treatment of COPD: struggle between oxidants and cytokines. | International journal of chronic obstructive pulmonary disease 20070901 |
| Bacterial lysate in the prevention of acute exacerbation of COPD and in respiratory recurrent infections. | International journal of chronic obstructive pulmonary disease 20070901 |
| Examination of lung toxicity, oxidant/antioxidant status and effect of erdosteine in rats kept in coal mine ambience. | Environmental toxicology and pharmacology 20070901 |
| Protective effects of erdosteine and vitamins C and E combination on ischemia-reperfusion-induced lung oxidative stress and plasma copper and zinc levels in a rat hind limb model. | Biological trace element research 20070701 |
| Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats. | Archives of medical research 20070501 |
| An overview of erdosteine antioxidant activity in experimental research. | Pharmacological research 20070401 |
| Erdosteine treatment attenuates oxidative stress and fibrosis in experimental biliary obstruction. | Pediatric surgery international 20070301 |
| The effects of erdosteine, N-acetylcysteine and vitamin E on nicotine-induced apoptosis of cardiac cells. | Journal of applied toxicology : JAT 20070101 |
| Clinical effects of erdosteine in the treatment of acute respiratory tract diseases in children. | International journal of clinical pharmacology and therapeutics 20070101 |
| Erdosteine ameliorates lung injury induced by transient aortic occlusion in rats. | Cardiovascular journal of Africa 20070101 |
| Regulation of sepsis-induced apoptosis of pulmonary cells by posttreatment of erdosteine and N-aceylcysteine. | Toxicology 20061207 |
| Pharmacological treatment of chronic obstructive pulmonary disease. | International journal of chronic obstructive pulmonary disease 20061201 |
| Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver. | Molecular and cellular biochemistry 20061001 |
| Protective effects of N-acetylcysteine and erdosteine on hemorrhagic shock-induced acute lung injury. | European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20061001 |
| Erdosteine against acetaminophen induced renal toxicity. | Molecular and cellular biochemistry 20060701 |
| Oxidative stress and redox regulation of lung inflammation in COPD. | The European respiratory journal 20060701 |
| Antioxidant therapeutic targets in COPD. | Current drug targets 20060601 |
| Role of mucolytics in the management of COPD. | International journal of chronic obstructive pulmonary disease 20060601 |
| Antioxidant therapies in COPD. | International journal of chronic obstructive pulmonary disease 20060301 |
| The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of pulmonary cells. | Toxicology 20060215 |
| Protein oxidation and lipid peroxidation after renal ischemia-reperfusion injury: protective effects of erdosteine and N-acetylcysteine. | Urological research 20060201 |
| Effects of erdosteine on bleomycin-induced lung fibrosis in rats. | Molecular and cellular biochemistry 20060101 |
| Comparison of the effects of erdosteine and N-acetylcysteine on apoptosis regulation in endotoxin-induced acute lung injury. | Journal of applied toxicology : JAT 20060101 |
| Hypobaric-hypoxia-induced pulmonary damage in rats ameliorated by antioxidant erdosteine. | Acta histochemica 20060101 |
| Effect of metabolite I of erdosteine on the release of human neutrophil elastase. | Pharmacology 20060101 |
| The protective role of erdosteine on testicular tissue after testicular torsion and detorsion. | Molecular and cellular biochemistry 20051201 |
| In vivo evidences suggesting the role of oxidative stress in pathogenesis of vancomycin-induced nephrotoxicity: protection by erdosteine. | Toxicology 20051115 |
| The protective effect of erdosteine against ototoxicity induced by cisplatin in rats. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20051001 |
| Protective agent, erdosteine, against cisplatin-induced hepatic oxidant injury in rats. | Molecular and cellular biochemistry 20051001 |
| The effects of isoniazid on hippocampal NMDA receptors: protective role of erdosteine. | Molecular and cellular biochemistry 20050901 |
| A combination of budesonide and the SH-metabolite I of erdosteine acts synergistically in reducing chemiluminescence during human neutrophil respiratory burst. | Pharmacology 20050601 |
| Erdosteine ameliorates PTZ-induced oxidative stress in mice seizure model. | Brain research bulletin 20050530 |
| Effects of erdosteine on smoking-induced lipid peroxidation in healthy smokers. | Drugs in R&D 20050101 |
| Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine. | Pulmonary pharmacology & therapeutics 20050101 |
| Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. | Respiratory research 20050101 |
| Erdosteine ameliorates neurological outcome and oxidative stress due to ischemia/reperfusion injury in rabbit spinal cord. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20041001 |
| The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats. | Pharmacological research 20040901 |
| Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats. | Nitric oxide : biology and chemistry 20040901 |
| Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue. | Toxicology and industrial health 20040901 |
| Inhibitory effects of metabolite I of erdosteine on the generation of nitric oxide and peroxynitrite chemiluminescence by human neutrophils. | Pharmacology 20040701 |
| Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats. | European journal of pharmacology 20040628 |
| Sensitive determination of erdosteine in human plasma by use of automated 96-well solid-phase extraction and LC-MS/MS. | Journal of pharmaceutical and biomedical analysis 20040218 |
| In vivo evidence suggesting a role for purine-catabolizing enzymes in the pathogenesis of cisplatin-induced nephrotoxicity in rats and effect of erdosteine against this toxicity. | Cell biochemistry and function 20040101 |
| Erdosteine improves oxidative damage in a rat model of renal ischemia-reperfusion injury. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101 |
| Cisplatin-induced acute renal failure is ameliorated by erdosteine in a dose-dependent manner. | Journal of applied toxicology : JAT 20040101 |
| Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats. | BMC pharmacology 20040101 |
| The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: the EQUALIFE Study. | Drugs under experimental and clinical research 20040101 |
| Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease [ISRCTN21676344]. | BMC pulmonary medicine 20040101 |
| Erdosteine prevents doxorubicin-induced cardiotoxicity in rats. | Pharmacological research 20031001 |
| The activities of tissue xanthine oxidase and adenosine deaminase and the levels of hydroxyproline and nitric oxide in rat hearts subjected to doxorubicin: protective effect of erdosteine. | Toxicology 20030930 |
| Effects of erdosteine treatment against doxorubicin-induced toxicity through erythrocyte and plasma oxidant/antioxidant status in rats. | Pharmacological research 20030401 |
| Depressant effects of ambroxol and erdosteine on cytokine synthesis, granule enzyme release, and free radical production in rat alveolar macrophages activated by lipopolysaccharide. | Pharmacology & toxicology 20030401 |
| Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats. | Pharmacological research 20030201 |
| Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats. | Journal of applied toxicology : JAT 20030101 |
| Effects on the reactive oxygen species of erdosteine and its metabolite in vitro. | Arzneimittel-Forschung 20020101 |
| The combination of the SH metabolite of erdosteine (a mucoactive drug) and ciprofloxacin increases the inhibition of bacterial adhesiveness achieved by ciprofloxacin alone. | Drugs under experimental and clinical research 20020101 |
| The SH-metabolite I of erdosteine, a mucolytic drug, enhances the inhibitory effect of salbutamol on the respiratory burst of neutrophils. | Drugs under experimental and clinical research 20020101 |
| Bacterial adhesiveness: effects of the SH metabolite of erdosteine (mucoactive drug) plus clarithromycin versus clarithromycin alone. | Chemotherapy 20010101 |
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