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Home > Pyridines > 844499-71-4
CAS No: 844499-71-4 Catalog No: AG0038EQ MDL No:MFCD11977269
Title | Journal |
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Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue. | Iranian journal of basic medical sciences 20161201 |
Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro. | Neuropharmacology 20160901 |
Bavachalcone-induced manganese superoxide dismutase expression through the AMP-activated protein kinase pathway in human endothelial cells. | Pharmacology 20150101 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells. | The Journal of pharmacology and experimental therapeutics 20120901 |
Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells. | The Journal of biological chemistry 20120706 |
The ancient drug salicylate directly activates AMP-activated protein kinase. | Science (New York, N.Y.) 20120518 |
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase. | The Biochemical journal 20120401 |
Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells. | Cell cycle (Georgetown, Tex.) 20120301 |
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS). | Analytical and bioanalytical chemistry 20120101 |
5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent. | The Journal of pharmacology and experimental therapeutics 20111201 |
A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. | Journal of molecular and cellular cardiology 20110701 |
Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway. | The Journal of pharmacology and experimental therapeutics 20110401 |
AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells. | Diabetologia 20110101 |
Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase. | Protein expression and purification 20101001 |
Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation. | The Journal of physiology 20100701 |
AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells. | Biochemical and biophysical research communications 20100604 |
Regulation of Na+-coupled glucose carrier SGLT1 by AMP-activated protein kinase. | Molecular membrane biology 20100401 |
Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species. | Free radical research 20100201 |
Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes. | The Journal of biological chemistry 20100115 |
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. | American journal of physiology. Cell physiology 20091201 |
A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle. | American journal of physiology. Cell physiology 20091001 |
Inhibitory effects of A-769662, a novel activator of AMP-activated protein kinase, on 3T3-L1 adipogenesis. | Biological & pharmaceutical bulletin 20090601 |
AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells. | American journal of physiology. Cell physiology 20090401 |
Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle. | Endocrinology 20090201 |
Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators. | IUBMB life 20090101 |
Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes. | Chemistry & biology 20081124 |
Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. | The Journal of biological chemistry 20071109 |
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. | The Journal of biological chemistry 20071109 |
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. | Cell metabolism 20060601 |
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