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84210-26-4

84210-26-4 | NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE

CAS No: 84210-26-4 Catalog No: AG00G8VL MDL No:

Product Description

Catalog Number:
AG00G8VL
Chemical Name:
NZ-419,5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE
CAS Number:
84210-26-4
IUPAC Name:
5-hydroxy-1-methylimidazolidine-2,4-dione
InChI:
InChI=1S/C4H6N2O3/c1-6-3(8)2(7)5-4(6)9/h3,8H,1H3,(H,5,7,9)
InChI Key:
UPSFNXFLBMJUQW-UHFFFAOYSA-N

Properties

Complexity:
167  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
130.038g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
130.103g/mol
Monoisotopic Mass:
130.038g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
69.6A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.4  

Literature

Title Journal
Serum accumulation of a creatinine oxidative metabolite (NZ-419: 5-hydroxy-1- methylhydatoin) as an intrinsic antioxidant in diabetic patients with or without chronic kidney disease. Clinical nephrology 20111001
Treatment with NZ-419 (5-Hydroxy-1-methylimidazoline-2,4-dione), a novel intrinsic antioxidant, against the progression of chronic kidney disease at stages 3 and 4 in rats. Biological & pharmaceutical bulletin 20100101
First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats. Biological & pharmaceutical bulletin 20090701

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