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83462-55-9 | DEOXYPYRIDINOLINE
CAS No: 83462-55-9 Catalog No: AG00G72W MDL No:
Product Description
Catalog Number:
AG00G72W
Chemical Name:
DEOXYPYRIDINOLINE
CAS Number:
83462-55-9
IUPAC Name:
2-amino-6-[4-(2-amino-2-carboxyethyl)-3-(3-amino-3-carboxypropyl)-5-hydroxypyridin-1-ium-1-yl]hexanoate
InChI:
InChI=1S/C18H28N4O7/c19-12(16(24)25)3-1-2-6-22-8-10(4-5-13(20)17(26)27)11(15(23)9-22)7-14(21)18(28)29/h8-9,12-14H,1-7,19-21H2,(H3-,23,24,25,26,27,28,29)
InChI Key:
ZAHDXEIQWWLQQL-UHFFFAOYSA-N
Properties
Complexity:
557
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
412.196g/mol
Formal Charge:
0
Heavy Atom Count:
29
Hydrogen Bond Acceptor Count:
10
Hydrogen Bond Donor Count:
6
Isotope Atom Count:
0
Molecular Weight:
412.443g/mol
Monoisotopic Mass:
412.196g/mol
Rotatable Bond Count:
12
Topological Polar Surface Area:
217A^2
Undefined Atom Stereocenter Count:
3
Undefined Bond Stereocenter Count:
0
XLogP3:
-7.6
Literature
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|---|---|
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| Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links. | Bone 20051201 |
| A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201 |
| Alendronate for osteoporosis in men with androgen-repleted hypogonadism. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20051201 |
| The treatment of osteoporosis in patients with rheumatoid arthritis receiving glucocorticoids: a comparison of alendronate and intranasal salmon calcitonin. | Rheumatology international 20051101 |
| Cyclical alendronate treatment in postmenopausal women with osteoporosis. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20051101 |
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| The threshold of bone mineral density for vertebral fractures in female patients with primary hyperparathyroidism. | European journal of endocrinology 20050901 |
| Clinical and biologic factors related to oral implant failure: a 2-year follow-up study. | Implant dentistry 20050901 |
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| Osteoclastic function is accelerated in male patients with type 2 diabetes mellitus: the preventive role of osteoclastogenesis inhibitory factor/osteoprotegerin (OCIF/OPG) on the decrease of bone mineral density. | Diabetes research and clinical practice 20050501 |
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| Detection of mature collagen in human dental enamel. | Calcified tissue international 20050201 |
| No effect of fluvastatin on the bone mineral density of children with minimal change glomerulonephritis and some focal mesangial cell proliferation, other than an ameliorating effect on their proteinuria. | Clinical nephrology 20050201 |
| Higher calcium urinary loss induced by a calcium sulphate-rich mineral water intake than by milk in young women. | The British journal of nutrition 20050201 |
| Prognostic value of urinary pyridinium crosslinks and their derivatives in multiple myeloma. | Annals of hematology 20050101 |
| Reduced collagen and ascorbic acid concentrations and increased proteolytic susceptibility with prelabor fetal membrane rupture in women. | Biology of reproduction 20050101 |
| Soy isoflavones may protect against orchidectomy-induced bone loss in aged male rats. | Calcified tissue international 20050101 |
| Urinary excretion of collagen degradation markers by sows during postpartum uterine involution. | Animal reproduction science 20050101 |
| Effects of an oral contraceptive containing drospirenone on bone turnover and bone mineral density. | Obstetrics and gynecology 20050101 |
| One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women. | Nutrition journal 20050101 |
| Dolomite supplementation improves bone metabolism through modulation of calcium-regulating hormone secretion in ovariectomized rats. | Journal of bone and mineral metabolism 20050101 |
| Accelerated bone turnover in pregnant women with McCune-Albright syndrome. | Gynecologic and obstetric investigation 20050101 |
| Dietary soy protein and isoflavones have no significant effect on bone and a potentially negative effect on the uterus of sexually mature intact Sprague-Dawley female rats. | Menopause (New York, N.Y.) 20050101 |
| Low dose of oral alendronate decreases bone turnover in Japanese patients with Paget's disease of bone. | Journal of bone and mineral metabolism 20050101 |
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| Characterization of the pharmacologic profile of a standardized soy extract in the ovariectomized rat model of menopause: effects on bone, uterus, and lipid profile. | Menopause (New York, N.Y.) 20050101 |
| Effect of Korean oriental medicine extract on bone mass as compared with alendronate in ovariectomized rats. | Journal of medicinal food 20050101 |
| Relation between homocysteine and biochemical bone turnover markers and bone mineral density in peri- and post-menopausal women. | Clinical chemistry and laboratory medicine 20050101 |
| Assessment of soy phytoestrogens' effects on bone turnover indicators in menopausal women with osteopenia in Iran: a before and after clinical trial. | Nutrition journal 20050101 |
| [The influence of hyperthyroidism and glucocorticosteroid treatment on bone metabolism in patients with Graves' disease and ophthalmopathy]. | Endokrynologia Polska 20050101 |
| The effect of D-003 (10 mg/day) on biochemical parameters of bone remodelling in postmenopausal women: a randomized, double-blind study. | International journal of clinical pharmacology research 20050101 |
| [The influence of treatment with substitutive or suppressive doses of thyroxine on biochemical bone turnover markers]. | Annales Academiae Medicae Stetinensis 20050101 |
| Calcitropic hormones, bone turnover, and lead exposure among female smelter workers. | Archives of environmental & occupational health 20050101 |
| Assessment of urinary bone markers for monitoring treatment of osteoporosis. | Clinical chemistry 20041201 |
| Reference database of biochemical markers of bone turnover for the Japanese female population. Japanese Population-based Osteoporosis (JPOS) Study. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20041201 |
| Relationship between bone resorption and adrenal sex steroids and their derivatives in oophorectomized women. | Fertility and sterility 20041201 |
| Bone density and contraception in adolescent girls. | Journal of pediatric and adolescent gynecology 20041201 |
| Bone biochemical markers in adolescent girls using either depot medroxyprogesterone acetate or an oral contraceptive. | Journal of pediatric and adolescent gynecology 20041201 |
| Inhibition of osteoporosis due to restricted food intake by the fish oils DHA and EPA and perilla oil in the rat. | Bioscience, biotechnology, and biochemistry 20041201 |
| Soy isoflavones improve bone metabolism in postmenopausal Japanese women. | Clinical and experimental pharmacology & physiology 20041201 |
| Vitamin E deficiency reduced lumbar bone calcium content in female rats. | The Medical journal of Malaysia 20041201 |
| [Relationship of deoxypyridinole excretion with bone density, serum estradiol and years of postmenopause in Mexican postmenopausic women]. | Archivos latinoamericanos de nutricion 20041201 |
| Neridronate prevents bone loss in patients receiving androgen deprivation therapy for prostate cancer. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041101 |
| Long-term sensitivity of uterus and hypothalamus/pituitary axis to 17beta-estradiol is higher than that of bone in rats. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041101 |
| Increased bone resorption in the proximal femur in patients with hemiplegia. | American journal of physical medicine & rehabilitation 20041101 |
| Intravenous pamidronate treatment of children under 36 months of age with osteogenesis imperfecta. | Bone 20041101 |
| [Serum osteoprotegrin and serum bone gamma-carboxyglutamine acid-containing protein are correlated with bone mineral density in normal women]. | Zhonghua yi xue za zhi 20041002 |
| Heel ultrasonography is not a good screening tool for bone loss after kidney and pancreas transplantation. | Clinical transplantation 20041001 |
| Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34). | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041001 |
| Short-term variations in bone remodeling markers of an oral contraception formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol: observational study in young postadolescent women. | Contraception 20041001 |
| Bone mineral density changes in young women: a two year study. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20041001 |
| Effect of polymyxin B-immobilized fiber on bone resorption in patients with sepsis. | Intensive care medicine 20040901 |
| Raloxifene treatment is associated with increased serum estradiol and decreased bone remodeling in healthy middle-aged men with low sex hormone levels. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040901 |
| A clinical assessment of the relationship between bone scintigraphy and serum biochemical markers in hemodialysis patients. | Annals of nuclear medicine 20040901 |
| A comparison of methods for measuring serum and urinary markers of bone metabolism in cats. | Research in veterinary science 20040801 |
| Supplementation with oral vitamin D3 and calcium during winter prevents seasonal bone loss: a randomized controlled open-label prospective trial. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040801 |
| Regulation of collagen deposition and lysyl oxidase by tumor necrosis factor-alpha in osteoblasts. | The Journal of biological chemistry 20040716 |
| Chronopharmacology of oxacalcitriol in 5/6 nephrectomized rats. | Life sciences 20040702 |
| Prevention of bone loss in paraplegics over 2 years with alendronate. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040701 |
| Osteoprotegerin and RANKL in the pathogenesis of thalassemia-induced osteoporosis: new pieces of the puzzle. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040501 |
| Effect of difructose anhydride III on calcium absorption in humans. | Bioscience, biotechnology, and biochemistry 20040501 |
| Ultrasound measurement of pregnancy-induced changes in maternal bone mass: a longitudinal, cross-sectional and biochemical study. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040501 |
| Long-term treatment of lasofoxifene preserves bone mass and bone strength and does not adversely affect the uterus in ovariectomized rats. | Endocrinology 20040401 |
| Dietary calcium, sodium, phosphorus, and protein and bone metabolism in elderly Japanese women: a pilot study using the duplicate portion sampling method. | Nutrition (Burbank, Los Angeles County, Calif.) 20040401 |
| Variability of collagen crosslinks: impact of sample collection period. | Calcified tissue international 20040401 |
| Chronopharmacology of oxacalcitriol in rat model of osteoporosis. | European journal of pharmacology 20040319 |
| Body mass index (BMI) and parameters of bone formation and resorption in postmenopausal women. | Maturitas 20040315 |
| Restoration of euthyroidism accelerates bone turnover in patients with subclinical hypothyroidism: a randomized controlled trial. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20040301 |
| The effect of the steroid-sparing response to low-dose methotrexate on bone metabolism in glucocorticoid-dependent asthmatics. | Clinica chimica acta; international journal of clinical chemistry 20040301 |
| Transdermal hormone replacement therapy improves vertebral bone density in primary biliary cirrhosis: results of a 1-year controlled trial. | Alimentary pharmacology & therapeutics 20040301 |
| Transdermal testosterone application: pharmacokinetics and effects on pubertal status, short-term growth, and bone turnover. | The Journal of clinical endocrinology and metabolism 20040201 |
| Relationship between pretreatment bone resorption and vertebral fracture incidence in postmenopausal osteoporotic women treated with risedronate. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040201 |
| [Effect of vitamin K2 and estrogen administration on bone formation]. | Nihon rinsho. Japanese journal of clinical medicine 20040201 |
| Effects of treadmill exercise on bone mass, bone metabolism, and calciotropic hormones in young growing rats. | Journal of bone and mineral metabolism 20040101 |
| Bone mass and metabolism in thalassemic children and adolescents treated with different iron-chelating drugs. | Journal of bone and mineral metabolism 20040101 |
| Prediction of the change in bone mineral density induced by gonadotropin-releasing hormone agonist treatment for endometriosis. | Fertility and sterility 20040101 |
| Effects of the phytoestrogen genistein on the circulating soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin system in early postmenopausal women. | The Journal of clinical endocrinology and metabolism 20040101 |
| The effects of binge alcohol exposure on bone resorption and biomechanical and structural properties are offset by concurrent bisphosphonate treatment. | Alcoholism, clinical and experimental research 20040101 |
| The effects of calcitonin on bone resorption in hyperthyroidism: a placebo-controlled clinical study. | Journal of bone and mineral metabolism 20040101 |
| Significance of serum CrossLaps as a predictor of changes in bone mineral density during estrogen replacement therapy; comparison with serum carboxyterminal telopeptide of type I collagen and urinary deoxypyridinoline. | Journal of bone and mineral metabolism 20040101 |
| Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study. | Arthritis research & therapy 20040101 |
| Regulation of mineral-to-matrix ratio of lumbar trabecular bone in ovariectomized rats treated with risedronate in combination with or without vitamin K2. | Journal of bone and mineral metabolism 20040101 |
| A comparison of incidences of vertebral fracture in Japanese patients with involutional osteoporosis treated with risedronate and etidronate: a randomized, double-masked trial. | Journal of bone and mineral metabolism 20040101 |
| Regulation of bone metabolism in immunosuppressant (FK506)-treated rats. | Journal of bone and mineral metabolism 20040101 |
| Inhibition of bone metastasis from breast cancer with pamidronate resulting in reduction of urinary pyridinoline and deoxypyridinoline in a rat model. | Breast cancer (Tokyo, Japan) 20040101 |
| The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia. | International journal of tissue reactions 20040101 |
| Paget's disease: a case in point. | Orthopedic nursing 20040101 |
| The heterogeneity of bone disease in cirrhosis: a multivariate analysis. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20031201 |
| Intestinal calcium absorption is associated with bone mass in stone-forming women with idiopathic hypercalciuria. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20031201 |
| Evaluation of serum concentrations of biochemical markers of bone metabolism and insulin-like growth factor I associated with treadmill exercise in young horses. | American journal of veterinary research 20031201 |
| Bone and calcium metabolism in subclinical autoimmune hyperthyroidism and hypothyroidism. | Endocrine journal 20031201 |
| Biochemical markers of types I and III collagen and limited joint mobility in type 1 diabetic patients. | Acta diabetologica 20031201 |
| Follow-up of collagen crosslink excretion in patients with oral squamous cell carcinoma and analysis of tissue samples. | British journal of cancer 20031103 |
| Older people in China and the United Kingdom differ in the relationships among parathyroid hormone, vitamin D, and bone mineral status. | Bone 20031001 |
| [Collagen breakdown in ankylosing spondylitis-relationship to disease related parameters]. | Zeitschrift fur Rheumatologie 20031001 |
| Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031001 |
| The response of a bone resorption marker to marine recruit training. | Military medicine 20031001 |
| The impact of different glucocorticoid replacement schedules on bone turnover and insulin sensitivity in patients with adrenal insufficiency. | Clinical endocrinology 20030901 |
| Urinary excretion of deoxypyridinoline increases after gastrointestinal surgery. | Nutrition (Burbank, Los Angeles County, Calif.) 20030901 |
| Effects on climacteric symptoms, bone and lipoprotein metabolism of hormone replacement therapy delivered by estradiol-releasing intravaginal rings: a pilot study. | Climacteric : the journal of the International Menopause Society 20030901 |
| Coumestrol as well as isoflavones in soybean extract prevent bone resorption in ovariectomized rats. | Endocrine regulations 20030901 |
| Action of green tea catechin on bone metabolic disorder in chronic cadmium-poisoned rats. | Life sciences 20030808 |
| Increased skin collagen extractability and proportions of collagen type III are not normalized after 6 months healing of human excisional wounds. | The Journal of investigative dermatology 20030801 |
| Urinary excretion of pyridinium cross-links and serum osteocalcin levels in patients with primary high-grade osteosarcoma. | Calcified tissue international 20030701 |
| Osteopontin facilitates bone resorption, decreasing bone mineral crystallinity and content during calcium deficiency. | Calcified tissue international 20030701 |
| The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women. | Clinical endocrinology 20030601 |
| Bone density in axial and appendicular skeleton in patients with lactose intolerance: influence of calcium intake and vitamin D status. | Journal of the American College of Nutrition 20030601 |
| Serum prolidase I activity and some bone metabolic markers in patients with breast cancer: in relation to menopausal status. | Clinical biochemistry 20030601 |
| Influence of smoking and oral contraceptives on bone mineral density and bone remodeling in young women: a 2-year study. | Contraception 20030601 |
| Biochemical indicator for evaluation of connective tissue abnormalities in Menkes' disease. | The Journal of pediatrics 20030601 |
| [Changes of urinary deoxypyridinoline crosslink/creatinine in rats after ovariectomy and anti-osteoporotic intervention]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030601 |
| A double-blind dose-ranging study of risedronate in Japanese patients with osteoporosis (a study by the Risedronate Late Phase II Research Group). | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20030501 |
| Effects of a low-dose and ultra-low-dose combined oral contraceptive use on bone turnover and bone mineral density in young fertile women: a prospective controlled randomized study. | Contraception 20030501 |
| Vitamin C and bone markers: investigations in a Gambian population. | The Proceedings of the Nutrition Society 20030501 |
| Collagen crosslink excretion and staging of oral cancer. | British journal of cancer 20030407 |
| Molecular markers in the evaluation of autologous chondrocyte implantation. | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 20030401 |
| The renal clearance of free and peptide-bound deoxypyridinoline: response to pamidronate treatment of Paget's disease. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030401 |
| Bone marker alterations in patients with type 1 Gaucher disease. | Calcified tissue international 20030301 |
| Effectiveness of alendronate treatment in postmenopausal women with osteoporosis: relationship with BsmI vitamin D receptor genotypes. | Clinical endocrinology 20030301 |
| Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis. | The Journal of rheumatology 20030301 |
| Comparison of vitamin C deficiency with food restriction on collagen cross-link ratios in bone, urine and skin of weanling guinea-pigs. | The British journal of nutrition 20030301 |
| The effects of pregnancy and lactation on hormonal status and biochemical markers of bone turnover. | European journal of obstetrics, gynecology, and reproductive biology 20030210 |
| Predominant factors associated with bone loss in liver transplant patients - after prolonged post-transplantation period. | Clinical transplantation 20030201 |
| Hydroxypyridinium collagen crosslinks in serum, urine, synovial fluid and synovial tissue in patients with rheumatoid arthritis compared with osteoarthritis. | Rheumatology (Oxford, England) 20030201 |
| Effects of cerivastatin on vascularized allogenic bone transplantation in rats treated with cyclosporine A. | Calcified tissue international 20030101 |
| Skeletal effects of cyclosporin A are gender related in rats. | Endocrinology 20030101 |
| Association between craniofacial growth and urinary bone metabolic markers (pyridinoline, deoxypyridinoline) in growing rats. | Journal of dental research 20030101 |
| Intravenous neridronate in adults with osteogenesis imperfecta. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030101 |
| Vitamin D receptor gene polymorphism and bone metabolism during low-dose oral contraceptive use in young women. | Contraception 20030101 |
| Raloxifene administration in post-menopausal women with osteoporosis: effect of different BsmI vitamin D receptor genotypes. | Human reproduction (Oxford, England) 20030101 |
| Changes in urinary bone resorption markers (pyridinoline, deoxypyridinoline) resulting from experimentally-induced osteoarthritis in the temporomandibular joint of rats. | Cranio : the journal of craniomandibular practice 20030101 |
| Analytical and clinical evaluation of the Bio-Rad HPLC kit for measurement of type I collagen cross links. | Journal of bone and mineral metabolism 20030101 |
| Effects of a herbal extract on the bone density, strength and markers of bone turnover of mature ovariectomized rats. | The American journal of Chinese medicine 20030101 |
| Pyridinoline cross-links as markers for primary and secondary bone tumors. | Scandinavian journal of clinical and laboratory investigation 20030101 |
| Clinical usefulness of measurements of urinary deoxypyridinoline (DPD) in patients with postmenopausal osteoporosis receiving intermittent cyclical etidronate: advantage of free form of DPD over total DPD in predicting treatment efficacy. | Journal of bone and mineral metabolism 20030101 |
| Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis. | Journal of bone and mineral metabolism 20030101 |
| Circulating levels of osteoclast activating cytokines, interleukin-11 and transforming growth factor-beta2, as valuable biomarkers for the assessment of bone turnover in postmenopausal osteoporosis. | Clinical laboratory 20030101 |
| Markers of bone resorption--measurement in serum, plasma or urine? | Clinical laboratory 20030101 |
| Influence of clenbuterol on bone metabolism in exercised or sedentary rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20021201 |
| A patient with sarcoidosis presenting with acute renal failure: implication for granulomatous interstitial nephritis and hypercalcemia. | Internal medicine (Tokyo, Japan) 20021201 |
| Bone metabolism and mass in women with Cushing's syndrome and adrenal incidentaloma. | Clinical endocrinology 20021101 |
| Shift of serum osteocalcin components between cord blood and blood at day 5 of life. | Pediatric research 20021101 |
| Diurnal, week-to-week, and long-term variation in urine deoxypyridinoline cross-link excretion in healthy older women. | Journal of the American Geriatrics Society 20021101 |
| The effect of micronized estradiol on bone turnover and calciotropic hormones in older men receiving hormonal suppression therapy for prostate cancer. | The Journal of clinical endocrinology and metabolism 20021101 |
| Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy. | The Journal of clinical endocrinology and metabolism 20021101 |
| Urinary creatinine instability falsely increases the deoxypyridinoline/creatinine quotient. | Clinica chimica acta; international journal of clinical chemistry 20021001 |
| Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021001 |
| Global skeletal uptake of 99mTc-methylene diphosphonate (GSU) in patients affected by endocrine diseases: comparison with biochemical markers of bone turnover. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20021001 |
| Bone resorption versus estrogen loss following oophorectomy and menopause. | Maturitas 20020930 |
| Time of day improves efficacy and reduces adverse reactions of vitamin D3 in 5/6 nephrectomized rat. | Life sciences 20020830 |
| Biochemical measurements in the prediction of histologic subtype of renal transplant bone disease in women. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20020801 |
| Short-term effects on linear growth and bone turnover in children randomized to receive prednisolone or dexamethasone. | Clinical endocrinology 20020801 |
| The effects of sulphasalazine on urinary excretion of the hydroxypyridinium crosslinks of collagen in patients with rheumatoid arthritis. | Yonsei medical journal 20020801 |
| Rapid inhibition of thyroxine-induced bone resorption in the rat by an orally active vitronectin receptor antagonist. | The Journal of pharmacology and experimental therapeutics 20020701 |
| Bone metabolism markers and bone mass in healthy pubertal boys and girls. | Clinical endocrinology 20020701 |
| Bone remodelling markers and serum cytokines in patients with hyperthyroidism. | Clinical endocrinology 20020701 |
| Cross-link profile of bone collagen correlates with structural organization of trabeculae. | Bone 20020701 |
| The impact of subcutaneous oestradiol implants on biochemical markers of bone turnover and bone mineral density in postmenopausal women. | BJOG : an international journal of obstetrics and gynaecology 20020701 |
| Ankylosing spondylitis, psoriatic arthritis, and reactive arthritis show increased bone resorption, but differ with regard to bone formation. | The Journal of rheumatology 20020701 |
| Bone mineral density and height gain in children with chronic cholestatic liver disease undergoing transplantation. | Transplantation 20020615 |
| Effects of osthole on postmenopausal osteoporosis using ovariectomized rats; comparison to the effects of estradiol. | Biological & pharmaceutical bulletin 20020601 |
| Serum prolidase activity as a marker of osteoporosis in type 2 diabetes mellitus. | Clinical biochemistry 20020601 |
| Usefulness of bone markers for detection of bone metastases in lung cancer patients. | Clinical biochemistry 20020601 |
| No major effect of estrogen receptor beta gene RsaI polymorphism on bone mineral density and response to alendronate therapy in postmenopausal osteoporosis. | The Journal of steroid biochemistry and molecular biology 20020601 |
| VDR gene polymorphisms are overrepresented in german patients with type 1 diabetes compared to healthy controls without effect on biochemical parameters of bone metabolism. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020601 |
| Single infusion of neridronate (6-amino-1-hydroxyhexylidene-1,1-bisphosphonate) in patients with active rheumatoid arthritis: effects on disease activity and bone resorption markers. | Aging clinical and experimental research 20020601 |
| Increased lead excretion in hypothyroid patients after levothyroxine medication. | Journal of toxicology and environmental health. Part A 20020510 |
| Increased bone resorption in the critically ill: association with sepsis and increased nitric oxide production. | Critical care medicine 20020401 |
| Beneficial effects of soybean isoflavone supplementation on bone metabolism and serum lipids in postmenopausal japanese women: a four-week study. | Journal of the American College of Nutrition 20020401 |
| Bone mineral density and lifestyle among female students aged 16-24 years. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020401 |
| Bone mineral metabolism and histomorphometry in rats with cholestatic liver disease. | Liver 20020401 |
| Heterogeneity in familial dominant Paget disease of bone and muscular dystrophy. | American journal of medical genetics 20020315 |
| Reductions in bone mass, structure, and strength in axial and appendicular skeletons associated with increased turnover after ovariectomy in mature cynomolgus monkeys and preventive effects of clodronate. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020301 |
| Biochemical development of subchondral bone from birth until age eleven months and the influence of physical activity. | Equine veterinary journal 20020301 |
| Predictors of bone mineral density in aging healthy men varies by skeletal site. | Calcified tissue international 20020301 |
| [Bone resorption marker]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| [Advance in the treatment of postmenopausal osteoporosis]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| [Treatment of male osteoporosis]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| Association of dehydroepiandrosterone sulfate and testosterone deficiency with bone turnover in men with inflammatory bowel disease. | International journal of colorectal disease 20020301 |
| The efficacy of two dosages of a continuous combined hormone replacement regimen. | Maturitas 20020226 |
| Assessment and recommendations on factors contributing to preanalytical variability of urinary pyridinoline and deoxypyridinoline. | Clinical chemistry 20020201 |
| Collagen markers deoxypyridinoline and hydroxylysine glycosides: pediatric reference data and use for growth prediction in growth hormone-deficient children. | Clinical chemistry 20020201 |
| Effect of etidronate on bone in orchidectomized and sciatic neurectomized adult rats. | Bone 20020201 |
| Effects of vitamin D analog, 22-oxa-1,25-dihydroxyvitamin D(3), on bone reconstruction by vascularized bone allograft. | Bone 20020201 |
| Changes in markers of bone metabolism during dexamethasone treatment for chronic lung disease in preterm infants. | Archives of disease in childhood. Fetal and neonatal edition 20020101 |
| [Levels of mature cross-links and advanced glycation end product cross-links in human vitreous]. | Nippon Ganka Gakkai zasshi 20020101 |
| Effects of dose and timing of calcium supplementation on bone resorption in early menopausal women. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101 |
| Urinary collagen cross-links as biochemical markers of growth: an evaluation of biological variables. | Annals of nutrition & metabolism 20020101 |
| Assessment of four biochemical markers of bone metabolism in postmenopausal osteoporosis. | Clinical laboratory 20020101 |
| Effects upon bone metabolism following total hip and total knee arthroplasty. | Pathobiology : journal of immunopathology, molecular and cellular biology 20020101 |
| [Bone remodeling assessment after total hip replacement]. | Annales de biologie clinique 20020101 |
| Levels of mature cross-links and advanced glycation end product cross-links in human vitreous. | Japanese journal of ophthalmology 20020101 |
| Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss. | Prostate cancer and prostatic diseases 20020101 |
| Effect of melatonin on bone metabolism in ovariectomized rats. | Life sciences 20011221 |
| Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine. | Pediatrics 20011201 |
| Comparison of biochemical markers of bone turnover and bone mineral density in different groups of climacteric women. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011201 |
| Comparison of blood markers for the longitudinal monitoring of osteoclastic activity in the pig. | Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20011201 |
| Loss of bone mass and vitamin D deficiency after hematopoietic stem cell transplantation: standard prophylactic measures fail to prevent osteoporosis. | Leukemia 20011101 |
| Effects of short-term use of ibuprofen or acetaminophen on bone resorption in healthy men: a double-blind, placebo-controlled pilot study. | Bone 20011101 |
| Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone. | Rheumatology (Oxford, England) 20011101 |
| The CAG repeat polymorphism in the androgen receptor gene affects bone density and bone metabolism in healthy males. | Clinical endocrinology 20011101 |
| Lack of influence of the androgen receptor gene CAG-repeat polymorphism on sex steroid status and bone metabolism in elderly men. | Clinical endocrinology 20011101 |
| Chronotherapy with active vitamin D3 in aged stroke-prone spontaneously hypertensive rats, a model of osteoporosis. | European journal of pharmacology 20011005 |
| Spectroscopic characterization of collagen cross-links in bone. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20011001 |
| The effect of calcium intake on bone composition and bone resorption in the young growing rat. | The British journal of nutrition 20011001 |
| Estrogens and bone health in men. | Calcified tissue international 20011001 |
| An open, crossover trial of calcium-fortified milk in prevention of early postmenopausal bone loss. | The Medical journal of Australia 20010903 |
| Diurnal variations in serum and urine markers of type I and type III collagen turnover in children. | Clinical chemistry 20010901 |
| Tibolone exerts its protective effect on trabecular bone loss through the estrogen receptor. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901 |
| Seasonal variation in bone turnover: dependence on calcium nutrition. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901 |
| Selenium deficiency-induced growth retardation is associated with an impaired bone metabolism and osteopenia. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801 |
| Bone metabolism and body composition in Japanese patients with active acromegaly. | Clinical endocrinology 20010801 |
| Early postmenopausal bone loss in hyperthyroidism. | Maturitas 20010725 |
| [Clinical value of urinary pyridinium crosslinks as osteoporosis markers: evaluation of a population survey of vertebral osteoporosis]. | Medizinische Klinik (Munich, Germany : 1983) 20010715 |
| Training affects the collagen framework of subchondral bone in foals. | Veterinary journal (London, England : 1997) 20010701 |
| Osteoprotegerin serum levels in men: correlation with age, estrogen, and testosterone status. | The Journal of clinical endocrinology and metabolism 20010701 |
| Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010701 |
| Calcium metabolism and bone mass in female rabbits during skeletal maturation: effects of dietary calcium intake. | Bone 20010701 |
| Changes in biochemical parameters of bone turnover and bone mineral density in post-pregnancy osteoporosis. | American journal of obstetrics and gynecology 20010701 |
| Early changes of bone histology and circulating markers of bone turnover after parathyroidectomy in hemodialysis patients with severe hyperparathyroidism. | Clinical nephrology 20010701 |
| Serum and urine markers of bone metabolism during the year after hip fracture. | Journal of the American Geriatrics Society 20010701 |
| Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics. | Bioorganic & medicinal chemistry 20010601 |
| Response of biochemical markers of bone turnover to estrogen treatment in post-menopausal women: evidence against an early anabolic effect on bone formation. | Journal of endocrinological investigation 20010601 |
| Changes in bone turnover following gonadotropin-releasing hormone (GnRH) agonist administration and estrogen treatment in cynomolgus monkeys: a short-term model for evaluation of antiresorptive therapy. | Bone 20010501 |
| The beneficial effect of OST-6 (OsteoCare), a herbomineral formulation, in experimental osteoporosis. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20010501 |
| Bisphosphonate inhibits alveolar bone resorption in experimentally-induced peri-implantitis in dogs. | Clinical oral implants research 20010401 |
| Inhaled corticosteroids reduce bone mineral density in early postmenopausal but not premenopausal asthmatic women. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401 |
| An assessment of genetic markers as predictors of bone turnover in healthy adults. | Journal of endocrinological investigation 20010401 |
| Prevention of secondary osteoporosis postmenopause in hemiplegia. | American journal of physical medicine & rehabilitation 20010301 |
| Analysis of the contribution of dydrogesterone to bone turnover changes in postmenopausal women commencing hormone replacement therapy. | The Journal of clinical endocrinology and metabolism 20010301 |
| Effect of coffee consumption on bone metabolism. | Bone 20010301 |
| Skeletal responsiveness to parathyroid hormone in pseudohypoparathyroidism. | European journal of endocrinology 20010301 |
| Effect of pamidronate in preventing local bone loss after total hip arthroplasty: a randomized, double-blind, controlled trial. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010301 |
| Serum crosslaps correlations with serum ICTP and urine DPD in hemodialyzed and peritoneally dialyzed patients. | Nephron 20010301 |
| Serum crosslaps in comparison to serum osteocalcin and urinary bone resorption markers. | Clinical biochemistry 20010301 |
| Clinical utility of biochemical marker of bone remodelling in patients with bone metastases of solid tumors. | The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 20010301 |
| Effects of gonadal steroid suppression on skeletal sensitivity to parathyroid hormone in men. | The Journal of clinical endocrinology and metabolism 20010201 |
| Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2. | The Journal of clinical endocrinology and metabolism 20010201 |
| Choosing an oestrogen replacement therapy in young adult women with Turner syndrome. | Clinical endocrinology 20010201 |
| Correlations between biochemical markers of bone resorption and creatinine excretion. | Scandinavian journal of clinical and laboratory investigation 20010201 |
| Phasic production of urinary pyridinium crosslinks in mice: the effect of ovariectomy. | Calcified tissue international 20010201 |
| Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101 |
| Bone minerals changes in obese women during a moderate weight loss with and without calcium supplementation. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101 |
| Bone resorption is increased in young adults with thalassaemia major. | British journal of haematology 20010101 |
| Reliability of spot samples for assessment of urinary excretion of pyridinoline in patients with rheumatoid arthritis. | Clinical and experimental rheumatology 20010101 |
| Intravenous 1alpha, 25[OH]2 vitamin D3 (calcitriol) pulse therapy for bone lesions in a murine model of chronic cadmium toxicosis. | International journal of experimental pathology 20010101 |
| Early changes in parameters of bone and mineral metabolism during therapy for hyper- and hypothyroidism. | Endocrine research 20010101 |
| Fluticasone propionate and budesonide do not influence bone metabolism in the long term treatment of asthma. | Allergologia et immunopathologia 20010101 |
| Are levels of bone turnover related to lower bone mass of adolescents previously fed a macrobiotic diet? | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101 |
| Commencing, continuing and stopping brisk walking: effects on bone mineral density, quantitative ultrasound of bone and markers of bone metabolism in postmenopausal women. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101 |
| Guidelines on the use of biochemical markers of bone turnover in osteoporosis (2001). | Journal of bone and mineral metabolism 20010101 |
| Changes in bone biochemical markers after high-dose cerivastatin treatment in a woman with osteogenesis imperfecta. | Journal of bone and mineral metabolism 20010101 |
| Alterations of collagen matrix in weight-bearing bones during skeletal unloading. | Connective tissue research 20010101 |
| [Bone metabolism as assessed with selected markers of bone turnover as well as densitometry analysis in patients after successful kidney transplantation]. | Przeglad lekarski 20010101 |
| Association between two types of vitamin d receptor gene polymorphism and bone status in premenopausal Japanese women. | Calcified tissue international 20010101 |
| Evidence that treatment with monophasic oral contraceptive formulations containing ethinylestradiol plus gestodene reduces bone resorption in young women. | Contraception 20000401 |
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