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81025-04-9 | Lactitol monohydrate
CAS No: 81025-04-9 Catalog No: AG0050GT MDL No:MFCD00150767
Product Description
Catalog Number:
AG0050GT
Chemical Name:
Lactitol monohydrate
CAS Number:
81025-04-9
Molecular Formula:
C12H26O12
Molecular Weight:
362.3276
MDL Number:
MFCD00150767
IUPAC Name:
(2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol;hydrate
InChI:
InChI=1S/C12H24O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h4-21H,1-3H2;1H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-;/m0./s1
InChI Key:
LXMBXZRLTPSWCR-XBLONOLSSA-N
SMILES:
OC[C@H]([C@H]([C@@H]([C@H](CO)O)O)O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O)O.O
UNII:
UH2K6W1Y64
Properties
Complexity:
343
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
9
Defined Bond Stereocenter Count:
0
Exact Mass:
362.142g/mol
Formal Charge:
0
Heavy Atom Count:
24
Hydrogen Bond Acceptor Count:
12
Hydrogen Bond Donor Count:
10
Isotope Atom Count:
0
Molecular Weight:
362.328g/mol
Monoisotopic Mass:
362.142g/mol
Rotatable Bond Count:
8
Topological Polar Surface Area:
202A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol. | Age (Dordrecht, Netherlands) 20120801 |
| Osmotic and stimulant laxatives for the management of childhood constipation. | The Cochrane database of systematic reviews 20120711 |
| [Hepatic encephalopathy and liver transplantation]. | Magyar sebeszet 20120401 |
| The effect of alternative sweeteners on batter rheology and cake properties. | Journal of the science of food and agriculture 20120115 |
| Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM. | PloS one 20120101 |
| [Influence of lactitol and lactulose on adhesion properties of Bacillus subtilis probiotic strains]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20120101 |
| Proteome reference map of Lactobacillus acidophilus NCFM and quantitative proteomics towards understanding the prebiotic action of lactitol. | Proteomics 20110901 |
| Prolonging the viability of Lactobacillus plantarum through the addition of prebiotics into the medium. | Journal of food science 20110801 |
| Lactitol or lactulose in the treatment of chronic constipation: result of a systematic. | Journal of the Indian Medical Association 20101101 |
| Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model. | Beneficial microbes 20100601 |
| Xylo-oligosaccharides and lactitol promote the growth of Bifidobacterium lactis and Lactobacillus species in pure cultures. | Beneficial microbes 20100601 |
| [Elderly hereditary hemorrhagic telangiectasia female with portosystemic encephalopathy]. | Rinsho shinkeigaku = Clinical neurology 20090501 |
| Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters. | The British journal of nutrition 20090201 |
| Intestinal metabolism of weaned piglets fed a typical United States or European diet with or without supplementation of tributyrin and lactitol. | Journal of animal science 20081101 |
| [Influence of the bifidobacteria and lactitol containing products on lypoperoxidation processes and intestinal microflora]. | Voprosy pitaniia 20080101 |
| [Prebiotic lactitol as a component of biopreparation from aerobic bacilli]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20080101 |
| The treatment of hepatic encephalopathy. | Metabolic brain disease 20071201 |
| Suppressive effect of partially hydrolyzed guar gum on transitory diarrhea induced by ingestion of maltitol and lactitol in healthy humans. | European journal of clinical nutrition 20070901 |
| Effects of low doses of lactitol on faecal microflora, pH, short chain fatty acids and gastrointestinal symptomology. | European journal of nutrition 20070901 |
| [A case of recurrent pneumatosis cystoides intestinalis associated with recurrent pneumoperitoneum]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20070901 |
| A study of the properties of tablets from the mixtures of directly compressible starch and directly compressible lactitol. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20070701 |
| Threshold for transitory diarrhea induced by ingestion of xylitol and lactitol in young male and female adults. | Journal of nutritional science and vitaminology 20070201 |
| Effects of lactitol on intestinal microflora and plasma endotoxin in patients with chronic viral hepatitis. | The Journal of infection 20070101 |
| Anemia impairs small intestinal absorption measured by intestinal permeability in children. | European annals of allergy and clinical immunology 20070101 |
| Molecular mobility and dynamic site heterogeneity in amorphous lactose and lactitol from erythrosin B phosphorescence. | Biophysical chemistry 20060920 |
| The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation. | Cellular microbiology 20060701 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Prevention of first overt episode of hepatic encephalopathy after TIPS: no easy task. | Hepatology (Baltimore, Md.) 20060501 |
| Carbohydrate preference, acid tolerance and bile tolerance in five strains of Bifidobacterium. | Journal of applied microbiology 20060401 |
| Short-chain fatty acid formation in the hindgut of rats fed oligosaccharides varying in monomeric composition, degree of polymerisation and solubility. | The British journal of nutrition 20051101 |
| Dietary lactitol fermentation increases circulating peptide YY and glucagon-like peptide-1 in rats and humans. | Nutrition (Burbank, Los Angeles County, Calif.) 20051001 |
| Attenuated response of the serum triglyceride concentration to ingestion of a chocolate containing polydextrose and lactitol in place of sugar. | Bioscience, biotechnology, and biochemistry 20051001 |
| Pharmacological prophylaxis of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt: a randomized controlled study. | Journal of hepatology 20050501 |
| Maximum permissive dosage of lactose and lactitol for transitory diarrhea, and utilizable capacity for lactose in Japanese female adults. | Journal of nutritional science and vitaminology 20050401 |
| [Nonabsorbable disaccharides for the treatment of hepatic encephalopathy--a systemic review of randomized clinical trials--a secondary publication]. | Ugeskrift for laeger 20050110 |
| Oxalate degradation by intestinal lactic acid bacteria in dogs and cats. | Veterinary microbiology 20040714 |
| Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo. | Glycobiology 20040701 |
| Effect of sugar alcohols on gut function and body composition in normal and cecectomized rats. | Experimental animals 20040701 |
| Combination of polydextrose and lactitol affects microbial ecosystem and immune responses in rat gastrointestinal tract. | The British journal of nutrition 20040601 |
| Constipation in adults. | Clinical evidence 20040601 |
| Non-absorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials. | BMJ (Clinical research ed.) 20040501 |
| Nonabsorbable disaccharides for hepatic encephalopathy. | The Cochrane database of systematic reviews 20040101 |
| [Compressibility of directly compressed forms of lactitol]. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20030901 |
| Effects of lactulose and lactitol on coliform bacteria and bacterial translocation in the caecum during 72-h starvation in rats. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030701 |
| Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial. | Journal of hepatology 20030101 |
| Tributyrin and lactitol synergistically enhanced the trophic status of the intestinal mucosa and reduced histamine levels in the gut of nursery pigs. | Journal of animal science 20020301 |
| Intestinal permeability in children: variation with age and reliability in the diagnosis of cow's milk allergy. | Acta paediatrica (Oslo, Norway : 1992) 20010501 |
| Lactitol or lactulose in the treatment of chronic hepatic encephalopathy: results of a meta-analysis. | Hepatology (Baltimore, Md.) 19920201 |
| Lactulose inhibits endotoxin induced tumour necrosis factor production by monocytes. An in vitro study. | Gut 19900201 |
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