200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 81024-43-3
81024-43-3 | (R)-Metoprolol
CAS No: 81024-43-3 Catalog No: AG0050GU MDL No:
Product Description
Catalog Number:
AG0050GU
Chemical Name:
(R)-Metoprolol
CAS Number:
81024-43-3
Molecular Formula:
C15H25NO3
Molecular Weight:
267.3639
IUPAC Name:
(2R)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
InChI:
InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3/t14-/m1/s1
InChI Key:
IUBSYMUCCVWXPE-CQSZACIVSA-N
SMILES:
COCCc1ccc(cc1)OC[C@@H](CNC(C)C)O
Properties
Complexity:
215
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
267.183g/mol
Formal Charge:
0
Heavy Atom Count:
19
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
267.369g/mol
Monoisotopic Mass:
267.183g/mol
Rotatable Bond Count:
9
Topological Polar Surface Area:
50.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.9
Literature
| Title | Journal |
|---|---|
| Poly(2-ethyl-2-oxazoline) as matrix excipient for drug formulation by hot melt extrusion and injection molding. | Macromolecular rapid communications 20121015 |
| Assessment of metoprolol tartrate dosage in the outpatient setting. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20121001 |
| Clinical evaluation of valsartan and metoprolol tartrate in treatment of diabetic nephropathy with positive β1-adrenergic and anti-angiotensin II type 1 receptor antibody. | Chinese medical journal 20121001 |
| Nebivolol and metoprolol: long-term effects on inflammation and oxidative stress in essential hypertension. | Scandinavian journal of clinical and laboratory investigation 20120901 |
| Beta-blockade for mitral regurgitation: could the management of valvular heart disease actually be moving into the 21st century? | Journal of the American College of Cardiology 20120828 |
| A randomized controlled phase IIb trial of beta(1)-receptor blockade for chronic degenerative mitral regurgitation. | Journal of the American College of Cardiology 20120828 |
| Pretreatment with low-dose β-adrenergic antagonist therapy does not affect severity of Takotsubo cardiomyopathy. | Clinical cardiology 20120801 |
| Co-extrusion as manufacturing technique for fixed-dose combination mini-matrices. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801 |
| Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload. | Journal of molecular and cellular cardiology 20120801 |
| β-AR polymorphisms and glycemic and lipid parameters in hypertensive individuals receiving carvedilol or metoprolol. | American journal of hypertension 20120801 |
| A rapid UHPLC method for the simultaneous determination of drugs from different therapeutic groups in surface water and wastewater. | Bulletin of environmental contamination and toxicology 20120701 |
| Successful treatment of thyrotoxic crisis after esophagectomy in an elderly woman with hyperthyroidism. | The Annals of thoracic surgery 20120601 |
| Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120601 |
| In-line NIR spectroscopy for the understanding of polymer-drug interaction during pharmaceutical hot-melt extrusion. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120501 |
| Developing a model of participation post-stroke: a mixed-methods approach. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20120401 |
| β-blockers in stage B: a precursor of heart failure. | Heart failure clinics 20120401 |
| Formulation and evaluation of delayed-onset extended-release tablets of metoprolol tartrate using hydrophilic-swellable polymers. | Acta pharmaceutica (Zagreb, Croatia) 20120301 |
| Enantioresolution of five β-blockers by reversed-phase high-performance liquid chromatography using fifteen chiral derivatizing reagents having amino acids or their amides as chiral auxiliaries on a cyanuric chloride platform. | Biomedical chromatography : BMC 20120201 |
| [Effects of Ginseng and Sanchi Compositions on the Ras signal transduction pathway of myocardial ischemic rats]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120201 |
| Beta-blockers for heart failure: an evidence based review answering practical therapeutic questions. | The Medical journal of Malaysia 20120201 |
| Antiatherogenic and Anti-Ischemic Properties of Traditional Chinese Medicine Xinkeshu via Endothelial Protecting Function. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Beta blocker use in subjects with type 2 diabetes mellitus and systolic heart failure does not worsen glycaemic control. | Cardiovascular diabetology 20120101 |
| Metoprolol-induced visual hallucinations: a case series. | Journal of medical case reports 20120101 |
| Health expenditure comparison of extended-release metoprolol succinate and immediate-release metoprolol tartarate. | ClinicoEconomics and outcomes research : CEOR 20120101 |
| Iontophoresis: a potential emergence of a transdermal drug delivery system. | Scientia pharmaceutica 20120101 |
| Therapeutic options for the treatment of hypertension in children and adolescents. | Clinical medicine insights. Circulatory, respiratory and pulmonary medicine 20120101 |
| The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients. | International journal of vascular medicine 20120101 |
| Sulfotanshinone sodium injection for unstable angina pectoris: a systematic review of randomized controlled trials. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| High-sensitivity cardiac troponin T: risk stratification tool in patients with symptoms of chest discomfort. | PloS one 20120101 |
| A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry. | Journal of analytical methods in chemistry 20120101 |
| Eudragit FS based colonic microparticls of metoprolol tartrate. | Acta poloniae pharmaceutica 20120101 |
| Heart rate and use of beta-blockers in stable outpatients with coronary artery disease. | PloS one 20120101 |
| Different cardiovascular responses to a resistance training session in hypertensive women receiving propanolol compared with normotensive controls. | TheScientificWorldJournal 20120101 |
| Preliminary study of prospective ECG-gated 320-detector CT coronary angiography in patients with ventricular premature beats. | PloS one 20120101 |
| [Advantages of quinapril therapy in patients with arterial hypertension and functional class III chronic heart failure with preserved left ventricular ejection fraction]. | Kardiologiia 20120101 |
| [The methods for the protection against counterfeit medications. Part 1. The estimation of the quality of metoprolol succinate substance and tablets from different manufacturers in terms of 'identity' and 'active ingredient content']. | Sudebno-meditsinskaia ekspertiza 20120101 |
| Photocatalytic degradation of metoprolol tartrate in suspensions of two TiO2-based photocatalysts with different surface area. Identification of intermediates and proposal of degradation pathways. | Journal of hazardous materials 20111230 |
| [The prevention of denhong injection on contrast-induced renal impairment after percutaneous coronary intervention]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20111201 |
| Drug release control and system understanding of sucrose esters matrix tablets by artificial neural networks. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111009 |
| Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy. | European heart journal 20111001 |
| Modulation of drug (metoprolol succinate) release by inclusion of hydrophobic polymer in hydrophilic matrix. | Drug development and industrial pharmacy 20110901 |
| A randomised study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery; rationale and design of DECREASE-XIII. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110901 |
| Degradation of pharmaceutical beta-blockers by electrochemical advanced oxidation processes using a flow plant with a solar compound parabolic collector. | Water research 20110801 |
| Beta-blockers for heart failure: why you should use them more. | The Journal of family practice 20110801 |
| Sustained-release and swelling characteristics of xanthan gum/ethylcellulose-based injection moulded matrix tablets: in vitro and in vivo evaluation. | Journal of pharmaceutical sciences 20110701 |
| Effects of paroxetine on the pharmacokinetics and pharmacodynamics of immediate-release and extended-release metoprolol. | Pharmacotherapy 20110701 |
| Polymer leaching from film coating: effects on the coating transport properties. | International journal of pharmaceutics 20110615 |
| Titration to target dose of bisoprolol vs. carvedilol in elderly patients with heart failure: the CIBIS-ELD trial. | European journal of heart failure 20110601 |
| Differential effects of nebivolol and metoprolol on central aortic pressure and left ventricular wall thickness. | Hypertension (Dallas, Tex. : 1979) 20110601 |
| Spectral data analyses and structure elucidation of metoprolol tartrate. | Drug testing and analysis 20110601 |
| Drug release mechanisms from Kollicoat SR:Eudragit NE coated pellets. | International journal of pharmaceutics 20110516 |
| Risk of new-onset diabetes mellitus associated with beta-blocker treatment for hypertension. | Current medical research and opinion 20110401 |
| Influence of metoprolol dosage release formulation on the pharmacokinetic drug interaction with paroxetine. | Journal of clinical pharmacology 20110301 |
| Functional genomics of serotonin receptor 2A (HTR2A): interaction of polymorphism, methylation, expression and disease association. | Neuromolecular medicine 20110301 |
| Pulsatile multiparticulate drug delivery system for metoprolol succinate. | Archives of pharmacal research 20110301 |
| Mineralization of metoprolol by electro-Fenton and photoelectro-Fenton processes. | The journal of physical chemistry. A 20110224 |
| Development and evaluation of injection-molded sustained-release tablets containing ethylcellulose and polyethylene oxide. | Drug development and industrial pharmacy 20110201 |
| Functional effects of β₁-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration. | Clinical research in cardiology : official journal of the German Cardiac Society 20110201 |
| Ethylene vinyl acetate as matrix for oral sustained release dosage forms produced via hot-melt extrusion. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110201 |
| Effect of permeation enhancers on the iontophoretic transport of metoprolol tartrate and the drug retention in skin. | Drug delivery 20110101 |
| Influence of candidate genes on attention problems in children: a longitudinal study. | Behavior genetics 20110101 |
| Effects of Flos carthami on CYP2D6 and on the Pharmacokinetics of Metoprolol in Rats. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| The development of instruments to measure the work disability assessment behaviour of insurance physicians. | BMC public health 20110101 |
| The effect of nebivolol versus metoprolol succinate extended release on asymmetric dimethylarginine in hypertension. | Journal of the American Society of Hypertension : JASH 20110101 |
| Effect of atenolol vs metoprolol succinate on vascular function in patients with hypertension. | Clinical cardiology 20110101 |
| Influence of receptor antagonists, local anesthetics, and denervation on microcirculation. | Eplasty 20110101 |
| The challenge to verify ceramide's role of apoptosis induction in human cardiomyocytes--a pilot study. | Journal of cardiothoracic surgery 20110101 |
| The causes, consequences, and treatment of left or right heart failure. | Vascular health and risk management 20110101 |
| Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography. | Scientia pharmaceutica 20110101 |
| Preparation and in vitro Characterization of Porous Carrier-Based Glipizide Floating Microspheres for Gastric Delivery. | Journal of young pharmacists : JYP 20110101 |
| A self-controlled case series to assess the effectiveness of beta blockers for heart failure in reducing hospitalisations in the elderly. | BMC medical research methodology 20110101 |
| Can self-reported disability assessment behaviour of insurance physicians be explained? Applying the ASE model. | BMC public health 20110101 |
| Medical Student Attitudes toward Complementary, Alternative and Integrative Medicine. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Simultaneous determination of amlodipine and valsartan. | Analytical chemistry insights 20110101 |
| Towards a brief definition of burnout syndrome by subtypes: development of the 'Burnout Clinical Subtypes Questionnaire' (BCSQ-12). | Health and quality of life outcomes 20110101 |
| Atrioventricular dissociation after electroconvulsive therapy. | Cardiology research and practice 20110101 |
| Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure--a randomized study. | Cardiovascular diabetology 20110101 |
| Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation. | Chemistry Central journal 20110101 |
| Rehydrated sterically stabilized phospholipid nanomicelles of budesonide for nebulization: physicochemical characterization and in vitro, in vivo evaluations. | International journal of nanomedicine 20110101 |
| Metachronous merkel cell carcinoma: a case report. | Case reports in dermatology 20110101 |
| Beyond readability: investigating coherence of clinical text for consumers. | Journal of medical Internet research 20110101 |
| Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. | Journal of advanced pharmaceutical technology & research 20110101 |
| Analytical Method for the Simultaneous Estimation of Hydrochlorothiazide and Metoprolol Tartrate using RP HPLC. | Indian journal of pharmaceutical sciences 20110101 |
| Development and optimization of metoprolol succinate gastroretentive drug delivery system. | Acta pharmaceutica (Zagreb, Croatia) 20101201 |
| Adolescents' health behaviors and obesity: Does race affect this epidemic? | Nutrition research and practice 20101201 |
| Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. | Healthcare informatics research 20101201 |
| Tablet splitting: Product quality assessment of metoprolol succinate extended release tablets. | International journal of pharmaceutics 20101130 |
| Rhabdomyolysis associated with phentermine. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101115 |
| Some cardiovascular therapeutics inhibit paraoxonase 1 (PON1) from human serum. | European journal of pharmacology 20101025 |
| Quality control of metoprolol extended-release formulations in the presence of ethanol. | Pharmeuropa bio & scientific notes 20101001 |
| Development of sustained release capsules containing 'coated matrix granules of metoprolol tartrate'. | AAPS PharmSciTech 20100901 |
| [Response to metoprolol succinate sustained-release tablets in correlation to pulse pressure, serum vascular endothelial growth factor and C-reactive protein in elderly hypertensive patients with chronic heart failure]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100901 |
| Sucrose esters with various hydrophilic-lipophilic properties: novel controlled release agents for oral drug delivery matrix tablets prepared by direct compaction. | Acta biomaterialia 20100801 |
| Heart failure in acute ischemic stroke. | Current cardiology reviews 20100801 |
| Correlation between the FT-IR characteristics and metoprolol tartrate release of methylcellulose-based patches. | International journal of pharmaceutics 20100615 |
| A design and evaluation of layered matrix tablet formulations of metoprolol tartrate. | AAPS PharmSciTech 20100601 |
| [Effects of Radix Ginseng and Radix Notoginseng formula on expressions of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1alpha in ischemic myocardium of rats with acute myocardial infarction]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100601 |
| Aqueous coating dispersion (pseudolatex) of zein improves formulation of sustained-release tablets containing very water-soluble drug. | Journal of colloid and interface science 20100501 |
| Suppressive effect of insulin infusion on chemokines and chemokine receptors. | Diabetes care 20100501 |
| Differences between beta-blockers in patients with chronic heart failure and chronic obstructive pulmonary disease: a randomized crossover trial. | Journal of the American College of Cardiology 20100427 |
| [Beta-blocking agents in the perioperative period of the non-cardiac surgery]. | Medicina clinica 20100424 |
| Deeper insight into the drug release mechanisms in Eudragit RL-based delivery systems. | International journal of pharmaceutics 20100415 |
| Assessment of the anaerobic degradation of six active pharmaceutical ingredients. | The Science of the total environment 20100401 |
| Measuring disability across cultures--the psychometric properties of the WHODAS II in older people from seven low- and middle-income countries. The 10/66 Dementia Research Group population-based survey. | International journal of methods in psychiatric research 20100301 |
| Osmotic pumping release from ethyl-hydroxypropyl-cellulose-coated pellets: a new mechanistic model. | Journal of controlled release : official journal of the Controlled Release Society 20100225 |
| Accidental overdose of tiotropium in a patient with atrial fibrillation. | The Annals of pharmacotherapy 20100201 |
| Comparative stability of repackaged metoprolol tartrate tablets. | International journal of pharmaceutics 20100129 |
| Correlation between the free volume and the metoprolol tartrate release of Metolose patches. | Journal of pharmaceutical and biomedical analysis 20100105 |
| Compulsive internet use among adolescents: bidirectional parent-child relationships. | Journal of abnormal child psychology 20100101 |
| Survival after prolonged resuscitation with 99 defibrillations due to Torsade De Pointes cardiac electrical storm: a case report. | Scandinavian journal of trauma, resuscitation and emergency medicine 20100101 |
| Isolated hepatic actinomycosis: a case report. | Journal of medical case reports 20100101 |
| The construct validity and reliability of the Turkish version of Spreitzer's psychological empowerment scale. | BMC public health 20100101 |
| Cardiac gap junction channels are upregulated by metoprolol: an unexpected effect of beta-blockers. | Pharmacology 20100101 |
| [Effect of beta-adrenoblockers on remodeling of myocardium and adhesive function of endothelium in patients with ischemic heart disease, complicated with chronic heart failure and atrial fibrillation]. | Kardiologiia 20100101 |
| Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study. | Cardiovascular diabetology 20100101 |
| Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis. | PloS one 20100101 |
| Study protocol: determinants of participation and quality of life of adolescents with cerebral palsy: a longitudinal study (SPARCLE2). | BMC public health 20100101 |
| Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence. | Vascular health and risk management 20100101 |
| Heart rate control with adrenergic blockade: clinical outcomes in cardiovascular medicine. | Vascular health and risk management 20100101 |
| Triple antiplatelet therapy for preventing vascular events: a systematic review and meta-analysis. | BMC medicine 20100101 |
| Thoracic aortic dissection in a 38-year-old man. | Air medical journal 20100101 |
| Optimization and establishment of a validated stability-indicating HPLC method for study of the stress degradation behavior of metoprolol succinate. | Journal of AOAC International 20100101 |
| Electrocardiographic abnormalities of takotsubo cardiomyopathy in a patient with paced ventricular rhythm. | Cardiology research and practice 20100101 |
| [Clinical, hemodynamic and neurohumoral effects of switching patients with chronic heart failure from not recommended -adrenoblockers to bisoprolol in ambulatory practice]. | Kardiologiia 20100101 |
| Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment. | Diabetology & metabolic syndrome 20100101 |
| Myotonic dystrophy initially presenting as tachycardiomyopathy successful catheter ablation of atrial flutter. | Cardiology research and practice 20100101 |
| Design, development and in-vitro evaluation of metoprolol tartrate tablets containing xanthan-tragacanth. | Acta poloniae pharmaceutica 20100101 |
| Advances in systolic heart failure. | F1000 medicine reports 20100101 |
| Measurement invariance of the kidney disease and quality of life instrument (KDQOL-SF) across veterans and non-veterans. | Health and quality of life outcomes 20100101 |
| Simultaneous quantitative determination of metoprolol, atorvastatin and ramipril in capsules by a validated stability-indicating RP-UPLC method. | Scientia pharmaceutica 20100101 |
| Preparation and in vivo evaluation of indomethacin loaded true nanoemulsions. | Scientia pharmaceutica 20100101 |
| Bisoprolol and heart failure: new frontiers. | Indian heart journal 20100101 |
| Beta-blockers and heart failure. | Indian heart journal 20100101 |
| Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. | Journal of young pharmacists : JYP 20100101 |
| [Evolution of oral drug forms of metoprolol: advantages of long acting modified release forms with modified release]. | Kardiologiia 20100101 |
| Profound thrombocytopenia after primary exposure to eptifibatide. | Drug, healthcare and patient safety 20100101 |
| Sleep quality in patients with hypertension: additional negative effect of drug therapy. | Sleep medicine 20091201 |
| Core-in-cup tablet design of metoprolol succinate and its evaluation for controlled release. | Current drug discovery technologies 20091201 |
| Characterisation of quaternary polymethacrylate films containing tartaric acid, metoprolol free base or metoprolol tartrate. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091101 |
| Modeling drug release from hot-melt extruded mini-matrices with constant and non-constant diffusivities. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091001 |
| What can primary care prescribing data tell us about individual adherence to long-term medication?-comparison to pharmacy dispensing data. | Pharmacoepidemiology and drug safety 20091001 |
| Effect on the nasal bioavailability of co-processing drug and bioadhesive carrier via spray-drying. | International journal of pharmaceutics 20090908 |
| Optimization of fluid bed formulations of metoprolol granules and tablets using an experimental design. | Drug development and industrial pharmacy 20090901 |
| Psychometric testing of the Chinese version of the Hooked on Nicotine Checklist in adolescents. | The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20090901 |
| The effectiveness of collaborative medicine reviews in delaying time to next hospitalization for patients with heart failure in the practice setting: results of a cohort study. | Circulation. Heart failure 20090901 |
| Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. | Pharmacotherapy 20090801 |
| Right ventricular function in ST elevation myocardial infarction: effect of reperfusion. | Clinical and investigative medicine. Medecine clinique et experimentale 20090801 |
| Development of injection moulded matrix tablets based on mixtures of ethylcellulose and low-substituted hydroxypropylcellulose. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628 |
| Porous pellets as drug delivery system. | Drug development and industrial pharmacy 20090601 |
| Increased anxiety and depression in Danish cardiac patients with a type D personality: cross-validation of the Type D Scale (DS14). | International journal of behavioral medicine 20090601 |
| CYP2D6 genotype and its relationship with metoprolol dose, concentrations and effect in patients with systolic heart failure. | The pharmacogenomics journal 20090601 |
| Physical compatibility of metoprolol tartrate injection with selected cardiovascular agents. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090601 |
| Association between mortality and persistent use of beta blockers and angiotensin-converting enzyme inhibitors in patients with left ventricular systolic dysfunction and coronary artery disease. | The American journal of cardiology 20090601 |
| {2-Hydr-oxy-3-[4-(2-methoxy-ethyl)-phen-oxy]prop-yl}isopropyl-ammonium hemisuccinate. | Acta crystallographica. Section E, Structure reports online 20090601 |
| Drug release mechanisms from ethylcellulose: PVA-PEG graft copolymer-coated pellets. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090501 |
| Chromatography-tandem mass spectrometry method for the simultaneous quantitation of metoprolol succinate and simvastatin in human plasma. | Journal of pharmaceutical and biomedical analysis 20090405 |
| Analysis of drug content and weight uniformity for half-tablets of 6 commonly split medications. | Journal of managed care pharmacy : JMCP 20090401 |
| Amiodarone-induced neurotoxicity. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090315 |
| Comparison of carvedilol and metoprolol on serum lipid concentration in diabetic hypertensive patients. | Diabetes, obesity & metabolism 20090301 |
| Atenolol is inferior to metoprolol in improving left ventricular function and preventing ventricular remodeling in dogs with heart failure. | Cardiology 20090301 |
| Fabrication of modified release tablet formulation of metoprolol succinate using hydroxypropyl methylcellulose and xanthan gum. | AAPS PharmSciTech 20090301 |
| Years-needed-to-treat to add 1 year of life: a new metric to estimate treatment effects in randomized trials. | European journal of heart failure 20090301 |
| Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions. | Xenobiotica; the fate of foreign compounds in biological systems 20090301 |
| Evaluation of injection moulding as a pharmaceutical technology to produce matrix tablets. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090101 |
| Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarction. | Cardiology 20090101 |
| The influence of Metolose structure on the free volume and the consequent metoprolol tartrate release of patches. | International journal of biological macromolecules 20090101 |
| Cerebral non-oxidative carbohydrate consumption in humans driven by adrenaline. | The Journal of physiology 20090101 |
| Metoprolol succinate combination in the treatment of hypertension. | Angiology 20090101 |
| Metoprolol succinate therapy associated with erythema multiforme. | Cardiology journal 20090101 |
| Preventing long term relapsing tinea unguium with topical anti-fungal cream: a case report. | Cases journal 20090101 |
| Synthesis and characterization of Zwitterionic co-polymers as matrices for sustained metoprolol tartrate delivery. | Journal of biomaterials science. Polymer edition 20090101 |
| Assessing the adequacy of self-reported alcohol abuse measurement across time and ethnicity: cross-cultural equivalence across Hispanics and Caucasians in 1992, non-equivalence in 2001-2002. | BMC public health 20090101 |
| EXACKTE(2): exploiting the clinical consultation as a knowledge transfer and exchange environment: a study protocol. | Implementation science : IS 20090101 |
| Occupational voice demands and their impact on the call-centre industry. | BMC public health 20090101 |
| [The use of metoprolol tartrate during restoration of sinus rhythm and its subsequent maintenance in patients with chronic atrial fibrillation]. | Kardiologiia 20090101 |
| Nebivolol and quinapril reduce p-wave duration and dispersion in hypertensive patients. | Indian pacing and electrophysiology journal 20090101 |
| Measuring patient perceptions about osteoporosis pharmacotherapy. | BMC research notes 20090101 |
| Massive choroidal hemorrhage after intravitreal administration of bevacizumab (Avastin) for AMD followed by controlateral sympathetic ophthalmia. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Survival among patients with left ventricular systolic dysfunction treated with atenolol. | Congestive heart failure (Greenwich, Conn.) 20090101 |
| The acute effect of Metoprolol upon NT-proBNP level in patients with congestive heart failure. | Romanian journal of internal medicine = Revue roumaine de medecine interne 20090101 |
| Transarterial Chemoembolization of Metastatic Colorectal Carcinoma with Drug-Eluting Beads, Irinotecan (DEBIRI): Multi-Institutional Registry. | Journal of oncology 20090101 |
| Cardiac MR elastography: comparison with left ventricular pressure measurement. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101 |
| Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report. | Case reports in medicine 20090101 |
| Stability studies of expired tablets of metoprolol tartrate and propranolol hydrochloride. Part 1. Content determination. | Acta poloniae pharmaceutica 20090101 |
| Stability studies of expired tablets of metoprolol tartrate and propranolol hydrochloride. Part 2. Dissolution study. | Acta poloniae pharmaceutica 20090101 |
| Comparative effectiveness of different beta-adrenergic antagonists on mortality among adults with heart failure in clinical practice. | Archives of internal medicine 20081208 |
| Comparative effectiveness of beta-blockers in elderly patients with heart failure. | Archives of internal medicine 20081208 |
| Dissociation between cardiomyocyte function and remodeling with beta-adrenergic receptor blockade in isolated canine mitral regurgitation. | American journal of physiology. Heart and circulatory physiology 20081201 |
| Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure). | The American journal of cardiology 20081201 |
| The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker. | Journal of cardiovascular pharmacology 20081201 |
| Controlled-release carvedilol in the management of systemic hypertension and myocardial dysfunction. | Vascular health and risk management 20081201 |
| Polyelectrolyte-drug complexes of lambda carrageenan and basic drugs: relevance of particle size and moisture content on compaction and drug release behavior. | Drug development and industrial pharmacy 20081101 |
| Should physicians initiate beta-blocker therapy in patients undergoing non-cardiac surgery? Insights from the POISE trial. | Polskie Archiwum Medycyny Wewnetrznej 20081101 |
| Influence of CYP2D6*10 on the pharmacokinetics of metoprolol in healthy Korean volunteers. | Journal of clinical pharmacy and therapeutics 20081001 |
| Simultaneous determination of metoprolol succinate and amlodipine besylate in human plasma by liquid chromatography-tandem mass spectrometry method and its application in bioequivalence study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080915 |
| Enantiospecific pharmacokinetics of metoprolol in CYP2D6 ultra-rapid metabolizers and correlation with exercise-induced heart rate. | European journal of clinical pharmacology 20080901 |
| Dilated cardiomyopathy: an unusual complication of clozapine therapy. | Nature clinical practice. Cardiovascular medicine 20080901 |
| Development and in-vitro evaluation of transdermal matrix films of metoprolol tartrate. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080901 |
| Impact of beta-blockers on sleep in patients with mild hypertension: a randomized trial between nebivolol and metoprolol. | Advances in therapy 20080901 |
| Using nurses and office staff to report prescribing errors in primary care. | International journal for quality in health care : journal of the International Society for Quality in Health Care 20080801 |
| Takotsubo cardiomyopathy in pregnancy. | Obstetrics and gynecology 20080801 |
| Parental problem drinking, parenting, and adolescent alcohol use. | Journal of behavioral medicine 20080601 |
| The comparative effects of metoprolol and perindopril on aortic elasticity in young patients with prehypertension. | Blood pressure monitoring 20080601 |
| [Observation on therapeutic effect of auricular acupuncture combined with body acupuncture for treatment of cardiac neurosis]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20080601 |
| Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. | Lancet (London, England) 20080531 |
| Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. | Circulation research 20080509 |
| Comparison of the efficacy of metoprolol and carvedilol for preventing atrial fibrillation after coronary bypass surgery. | International journal of cardiology 20080507 |
| Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501 |
| Cryo-irradiation as a terminal method for the sterilization of drug aqueous solutions. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501 |
| Genetic and environmental influences on individual differences in attitudes toward homosexuality: an Australian twin study. | Behavior genetics 20080501 |
| Development and validation of a stereoselective liquid chromatography-tandem mass spectrometry assay for quantification of S- and R-metoprolol in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401 |
| Stability of metoprolol tartrate injection 1 mg/mL undiluted and 0.5 mg/mL in 0.9% sodium chloride injection and 5% dextrose injection. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080401 |
| Preferred drug lists: potential impact on healthcare economics. | Vascular health and risk management 20080401 |
| Differential effects of carvedilol and metoprolol succinate on plasma norepinephrine release and peak exercise heart rate in subjects with chronic heart failure. | Journal of cardiovascular pharmacology and therapeutics 20080301 |
| Simultaneous determination of metoprolol succinate and amlodipine besylate in pharmaceutical dosage form by HPLC. | Journal of pharmaceutical and biomedical analysis 20080213 |
| Comparative efficacy of two different beta-blockers on 24-hour blood pressure control. | Journal of clinical hypertension (Greenwich, Conn.) 20080201 |
| Heritability of self-reported phobic fear. | Behavior genetics 20080101 |
| Treatment with metoprolol succinate, a selective beta adrenergic blocker, lowers blood pressure without altering insulin sensitivity in diabetic patients. | Journal of clinical hypertension (Greenwich, Conn.) 20080101 |
| Scale development: factors affecting diet, exercise, and stress management (FADESM). | BMC public health 20080101 |
| Pediatric heart failure therapy with beta-adrenoceptor antagonists. | Paediatric drugs 20080101 |
| [Controlled release metoprolol succinate in MERIT-HF. Analysis of patients subgroups]. | Kardiologiia 20080101 |
| Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement. | Journal of anesthesia 20080101 |
| Preoperative prophylaxis can decrease rates of atrial fibrillation in open heart surgery: a retrospective study. | The heart surgery forum 20080101 |
| A review of evidence-based beta-blockers in special populations with heart failure. | Reviews in cardiovascular medicine 20080101 |
| Takotsubo cardiomyopathy associated with anesthesia: three case reports. | Cases journal 20080101 |
| Survival in a patient with severe paraneoplastic hyponatremia: a case report. | Cases journal 20080101 |
| Spectrophotometric and column high-performance liquid chromatographic methods for simultaneous estimation of metoprolol tartrate and hydrochlorothiazide in tablets. | Journal of AOAC International 20080101 |
| Switching to evidence-based once-daily beta-blockers for improved adherence to medication across the continuum of post-myocardial infarction left ventricular dysfunction and heart failure. | Congestive heart failure (Greenwich, Conn.) 20080101 |
| [Efficacy and safety of metoprolol CR/XL: confidence based on proofs]. | Kardiologiia 20080101 |
| Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) study. | Journal of the cardiometabolic syndrome 20080101 |
| Septic rupture of the ascending aorta after aortocoronary bypass surgery. | Journal of cardiothoracic surgery 20080101 |
| Usability laboratory test of a novel mobile homecare application with experienced home help service staff. | The open medical informatics journal 20080101 |
| Formulation, and Evaluation of Pentoxifylline-Loaded Poly(epsilon-caprolactone) Microspheres. | Indian journal of pharmaceutical sciences 20080101 |
| Formulation optimization of propranolol hydrochloride microcapsules employing central composite design. | Indian journal of pharmaceutical sciences 20080101 |
| Herbal excipients in novel drug delivery systems. | Indian journal of pharmaceutical sciences 20080101 |
| New Spectrophotometric Method for Simultaneous determination of Metoprolol Tartarate and Hydrochlorthiazide in Tablets. | Indian journal of pharmaceutical sciences 20080101 |
| Design and optimization of diclofenac sodium controlled release solid dispersions by response surface methodology. | Indian journal of pharmaceutical sciences 20080101 |
| Furosemide-loaded Alginate Microspheres Prepared by Ionic Cross-linking Technique: Morphology and Release Characteristics. | Indian journal of pharmaceutical sciences 20080101 |
| Development and in vitro evaluation of buccoadhesive tablets of metoprolol tartrate. | Indian journal of pharmaceutical sciences 20080101 |
| Effects of metoprolol succinate extended release vs. amlodipine besylate on the blood pressure, heart rate, and the rate-pressure product in patients with hypertension. | Journal of the American Society of Hypertension : JASH 20080101 |
| Key formulation variables in tableting of coated pellets. | Indian journal of pharmaceutical sciences 20080101 |
| Switching to once-daily evidence-based [beta]-blockers in patients with systolic heart failure or left ventricular dysfunction after myocardial infarction. | Critical care nurse 20071201 |
| Effect of carvedilol and metoprolol on the mode of death in patients with heart failure. | European journal of heart failure 20071101 |
| [Beta-adrenoceptor antagonists and ACE-inhibitors. Carvedilol compared with metoprolol as combination partner in cases of diabetes and hypertension]. | Deutsche medizinische Wochenschrift (1946) 20071101 |
| Lowering blood pressure with beta-blockers in combination with other renin-angiotensin system blockers in patients with hypertension and type 2 diabetes: results from the GEMINI Trial. | Journal of clinical hypertension (Greenwich, Conn.) 20071101 |
| Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid. | Journal of agricultural and food chemistry 20071031 |
| Heart rate reduction after heart transplantation with beta-blocker versus the selective If channel antagonist ivabradine. | Transplantation 20071027 |
| Liquid chromatography tandem mass spectrometry method for simultaneous determination of metoprolol tartrate and ramipril in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015 |
| Effect of beta-blocker therapy on left atrial function in patients with heart failure: comparison of metoprolol succinate with carvedilol. | The international journal of cardiovascular imaging 20071001 |
| The influence of formulation factors on the kinetic release of metoprolol tartrate from prolong release coated minitablets. | Drug development and industrial pharmacy 20071001 |
| A critical review of anti-adrenergic therapy in patients with heart failure and diabetes mellitus. | Vascular health and risk management 20071001 |
| Nebivolol in the treatment of chronic heart failure. | Vascular health and risk management 20071001 |
| Beta-adrenergic receptor antagonists and chronic heart failure in children. | Therapeutics and clinical risk management 20071001 |
| Correlation between the permeability of metoprolol tartrate through plasticized isolated ethylcellulose/hydroxypropyl methylcellulose films and drug release from reservoir pellets. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070901 |
| Porous hydroxyapatite tablets as carriers for low-dosed drugs. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070901 |
| Comparative effectiveness of beta-adrenergic antagonists (atenolol, metoprolol tartrate, carvedilol) on the risk of rehospitalization in adults with heart failure. | The American journal of cardiology 20070815 |
| Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET). | Heart (British Cardiac Society) 20070801 |
| Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial. | European journal of heart failure 20070801 |
| Bisoprolol in the treatment of chronic heart failure. | Vascular health and risk management 20070801 |
| Bisoprolol in the treatment of chronic heart failure: from pathophysiology to clinical pharmacology and trial results. | Therapeutics and clinical risk management 20070801 |
| Assessment and etiology of attention deficit hyperactivity disorder and oppositional defiant disorder in boys and girls. | Behavior genetics 20070701 |
| Differential effect of beta-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI. | Diabetic medicine : a journal of the British Diabetic Association 20070701 |
| Effects of carvedilol versus metoprolol on endothelial function and oxidative stress in patients with type 2 diabetes mellitus. | American journal of hypertension 20070701 |
| Body weight changes with beta-blocker use: results from GEMINI. | The American journal of medicine 20070701 |
| Clinical reminders attached to echocardiography reports of patients with reduced left ventricular ejection fraction increase use of beta-blockers: a randomized trial. | Circulation 20070605 |
| Preoperative beta-blocker use reduces atrial fibrillation in off-pump coronary bypass surgery. | ANZ journal of surgery 20070601 |
| Effect of metoprolol on heart rate variability in symptomatic patients with mitral valve prolapse. | The American journal of cardiology 20070601 |
| Rational pharmacoeconomics? | The New Zealand medical journal 20070601 |
| Metoprolol succinate extended release/hydrochlorothiazide combination tablets. | Vascular health and risk management 20070601 |
| Therapy with cardiac contractility modulation electrical signals improves left ventricular function and remodeling in dogs with chronic heart failure. | Journal of the American College of Cardiology 20070529 |
| Determination of beta-blockers and beta2-agonists in sewage by solid-phase extraction and liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20070504 |
| Does coronary artery bypass surgery affect metoprolol bioavailability. | European journal of clinical pharmacology 20070501 |
| beta-blocker use and diabetes symptom score: results from the GEMINI study. | Diabetes, obesity & metabolism 20070501 |
| Process analytical technology: chemometric analysis of Raman and near infra-red spectroscopic data for predicting physical properties of extended release matrix tablets. | Journal of pharmaceutical sciences 20070501 |
| Tolerability of beta-blockers in outpatients with refractory heart failure who were receiving continuous milrinone. | Pharmacotherapy 20070501 |
| Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study. | Circulation 20070417 |
| Nitric oxide, erectile dysfunction and beta-blocker treatment (MR NOED study): benefit of nebivolol versus metoprolol in hypertensive men. | Clinical and experimental pharmacology & physiology 20070401 |
| Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial. | Vascular health and risk management 20070401 |
| Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. | Journal of the American College of Cardiology 20070306 |
| The association between conduct problems and the initiation and progression of marijuana use during adolescence: a genetic analysis across time. | Behavior genetics 20070301 |
| Exploring the relationship between genetic and environmental influences on initiation and progression of substance use. | Addiction (Abingdon, England) 20070301 |
| Effect of beta blockers (carvedilol or metoprolol XL) in patients with transposition of great arteries and dysfunction of the systemic right ventricle. | The American journal of cardiology 20070301 |
| Efficacy and safety of extended release metoprolol succinate in hypertensive children 6 to 16 years of age: a clinical trial experience. | The Journal of pediatrics 20070201 |
| Acute hemodynamic effects of moderate doses of nebivolol versus metoprolol in patients with systolic heart failure. | International journal of clinical pharmacology and therapeutics 20070201 |
| Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial. | Vascular health and risk management 20070201 |
| Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. | Vascular health and risk management 20070201 |
| Sustained release of highly water-soluble drugs with micelle forming ability from polyionic matrix tablets. | Die Pharmazie 20070101 |
| Assessment of Survivor Concerns (ASC): a newly proposed brief questionnaire. | Health and quality of life outcomes 20070101 |
| [The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin]. | Klinicheskaia meditsina 20070101 |
| Comparative bioavailability of metoprolol tartrate after oral and transdermal administration in healthy male volunteers. | Clinical drug investigation 20070101 |
| [Administration of cardioselective beta-adrenoblockers in patients with arterial hypertension and/or ischemic heart disease associated with bronchoobstructive syndrome]. | Terapevticheskii arkhiv 20070101 |
| [beta-Adrenoblockers in cardiology: metoprolol succinate]. | Kardiologiia 20070101 |
| The psychometric properties of the Chinese version of the Fagerstrom Test for Nicotine Dependence. | Addictive behaviors 20061201 |
| Candesartan in heart failure. | Clinical interventions in aging 20061201 |
| Betaxolol is equivalent to carvedilol in patients with heart failure NYHA II or III: result of a randomized multicenter trial (BETACAR Trial). | International journal of cardiology 20061110 |
| Effect of alpha1-adrenergic receptors in cardiac pathophysiology. | American heart journal 20061101 |
| Drugs acting as plasticizers in polymeric systems: a quantitative treatment. | Journal of controlled release : official journal of the Controlled Release Society 20061027 |
| Determination of metoprolol tartrate in tablets and human urine using flow-injection chemiluminescence method. | Journal of pharmaceutical and biomedical analysis 20060926 |
| Effects of metoprolol tartrate therapy in patients with heart failure. | Arquivos brasileiros de cardiologia 20060901 |
| Presence and development of atrial fibrillation in chronic heart failure. Experiences from the MERIT-HF Study. | European journal of heart failure 20060801 |
| Beta1-adrenoceptor blockade mitigates excessive norepinephrine release into cardiac interstitium in mitral regurgitation in dog. | American journal of physiology. Heart and circulatory physiology 20060701 |
| Detection of myocardial bridging with ECG-gated MDCT and multiplanar reconstruction. | AJR. American journal of roentgenology 20060601 |
| The impact of new onset anaemia on morbidity and mortality in chronic heart failure: results from COMET. | European heart journal 20060601 |
| Carvedilol versus Metoprolol for the prevention of atrial fibrillation after off-pump coronary bypass surgery: rationale and design of the Carvedilol or Metoprolol Post-Revascularization Atrial Fibrillation Controlled Trial (COMPACT). | Cardiovascular drugs and therapy 20060601 |
| [The factors influencing metoprolol succinate release from hydroxypropyl methylcellulose matrix tablet]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20060601 |
| The use of metoprolol CR/XL in the treatment of patients with diabetes and chronic heart failure. | Vascular health and risk management 20060601 |
| The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy. | Journal of the American College of Cardiology 20060502 |
| Metoprolol succinate, a selective beta-adrenergic blocker, has no effect on insulin sensitivity. | Journal of clinical hypertension (Greenwich, Conn.) 20060501 |
| Development of an oral sustained release drug delivery system utilizing pH-dependent swelling of carboxyvinyl polymer. | Journal of controlled release : official journal of the Controlled Release Society 20060410 |
| Optimization of bilayer floating tablet containing metoprolol tartrate as a model drug for gastric retention. | AAPS PharmSciTech 20060407 |
| A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT). | American journal of hypertension 20060401 |
| The effect of extended-release metoprolol succinate on C-reactive protein levels in persons with hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20060401 |
| [Effect of oral cordarone in reversing persistent atrial fibrillation]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060401 |
| Modulated release metoprolol succinate formulation based on ionic interactions: in vivo proof of concept. | Journal of controlled release : official journal of the Controlled Release Society 20060310 |
| Effects of metoprolol therapy on cardiac troponin-I levels after elective percutaneous coronary interventions. | European heart journal 20060301 |
| In vivo biotransformation of metoprolol in the horse and on-column esterification of the aminocarboxylic acid metabolite by alcohols during solid phase extraction using mixed mode columns. | Journal of pharmaceutical and biomedical analysis 20060123 |
| Use of natural gums and cellulose derivatives in production of sustained release metoprolol tablets. | Drug delivery 20060101 |
| Comparison of carvedilol and metoprolol in patients with acute myocardial infarction undergoing primary coronary intervention--the PASSAT Study. | Clinical research in cardiology : official journal of the German Cardiac Society 20060101 |
| Preparation and characterization of metoprolol controlled-release solid dispersions. | Drug delivery 20060101 |
| Cardiomyopathy, familial dilated. | Orphanet journal of rare diseases 20060101 |
| Randomized, double-blind comparison of acute beta1-blockade with 50 mg metoprolol tartrate vs 25 mg carvedilol in normal subjects. | Congestive heart failure (Greenwich, Conn.) 20060101 |
| A Randomized Trial Oral Propranolol versus Metroprolol in Treatment of Neurally Medicated Cyncope. | Indian heart journal 20060101 |
| Differential effects of beta-blockers on albuminuria in patients with type 2 diabetes. | Hypertension (Dallas, Tex. : 1979) 20051201 |
| Influence of chronic renal failure on stereoselective metoprolol metabolism in hypertensive patients. | Journal of clinical pharmacology 20051201 |
| Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United kingdom. | Environmental health perspectives 20051201 |
| Economic implications of extended-release metoprolol succinate for heart failure in the MERIT-HF trial: a US perspective of the MERIT-HF trial. | Journal of cardiac failure 20051201 |
| Development of three layered buccal compact containing metoprolol tartrate by statistical optimization technique. | International journal of pharmaceutics 20051104 |
| Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial. | European heart journal 20051101 |
| Chronotropic incompetence as a predictor of death among patients with normal electrograms taking beta blockers (metoprolol or atenolol). | The American journal of cardiology 20051101 |
| [Effects of beta-blockers on transmitral, pulmonary venous flows, and spontaneous echo-contrast grades in heart failure]. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20050901 |
| Carvedilol improves myocardial contractility compared with metoprolol in patients with chronic hibernating myocardium after revascularization. | Journal of cardiovascular pharmacology and therapeutics 20050901 |
| Beta blocker effects on plasma homocysteine levels in patients with hypertension. | Atherosclerosis 20050801 |
| Do metoprolol and carvedilol have equivalent effects on diurnal heart rate in patients with chronic heart failure? | European journal of heart failure 20050801 |
| Validated kinetic spectrophotometric method for the determination of metoprolol tartrate in pharmaceutical formulations. | Chemical & pharmaceutical bulletin 20050801 |
| Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. | European journal of heart failure 20050801 |
| Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET. | European heart journal 20050701 |
| Effects of long-term beta-blocker therapy on P-wave duration and dispersion in patients with rheumatic mitral stenosis. | International journal of cardiology 20050622 |
| [Does the use of metoprolol-succinate in patients with chronic heart failure lead to a higher efficacy in treatment without causing additional costs?]. | MMW Fortschritte der Medizin 20050616 |
| In vitro-in vivo extrapolation of CYP2D6 inactivation by paroxetine: prediction of nonstationary pharmacokinetics and drug interaction magnitude. | Drug metabolism and disposition: the biological fate of chemicals 20050601 |
| Exchange of beta-blockers in heart failure patients. Experiences from the poststudy phase of COMET (the Carvedilol or Metoprolol European Trial). | European journal of heart failure 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Death and hospitalization in heart failure patients receiving carvedilol vs. metoprolol tartrate. | International journal of cardiology 20050310 |
| [Beta blockers for therapy of chronic heart failure]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210 |
| Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. | American heart journal 20050201 |
| What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF). | Journal of the American College of Cardiology 20050118 |
| Efficacy, safety and tolerability of metoprolol CR/XL in patients with diabetes and chronic heart failure: experiences from MERIT-HF. | American heart journal 20050101 |
| Tissue Doppler echocardiographic quantification. Comparison to coronary angiography results in Acute Coronary Syndrome patients. | Cardiovascular ultrasound 20050101 |
| [Antiischemic and metabolic effects of nebivolol and metaprolol CR/XL (betalok ZOK) in patients with postinfarction heart dysfunction]. | Klinicheskaia meditsina 20050101 |
| Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis. | Journal of cardiac failure 20041201 |
| Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial. | JAMA 20041110 |
| Pharmacokinetic evaluation of guar gum-based three-layer matrix tablets for oral controlled delivery of highly soluble metoprolol tartrate as a model drug. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20041101 |
| Reassessing guidelines for heart failure. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20040901 |
| Therapeutic update: non-selective beta- and alpha-adrenergic blockade in patients with coexistent chronic obstructive pulmonary disease and chronic heart failure. | Journal of the American College of Cardiology 20040804 |
| On call. I am a 64-year-old man, quite healthy except for high blood pressure, which was diagnosed last year. My doctor gave me Hydro-Diuril, which was only partly successful. Then he added Prinivil, but I had to stop it because of a terrible cough. Now he wants me to take Lopressor, but I've read the package insert and I'm worried about side effects--especially sexual problems, since I already have problems in that area. Do I have to take the pills? | Harvard men's health watch 20040801 |
| Comprehensive adrenergic receptor blockade with carvedilol is superior to beta-1-selective blockade with metoprolol in patients with heart failure: COMET. | Current heart failure reports 20040701 |
| Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo. | Circulation 20040629 |
| Food effects on tablet disintegration. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040601 |
| Long-term oral carvedilol in chronic heart failure. | Expert opinion on pharmacotherapy 20040601 |
| Commentary on the Carvedilol or Metoprolol European Trial (COMET). | The American journal of cardiology 20040506 |
| The update on the rationale, use and selection of beta-blockers in heart failure. | Current opinion in cardiology 20040501 |
| The use of beta-blockers in a tertiary care heart failure clinic: dosing, tolerance, and outcomes. | Archives of internal medicine 20040412 |
| Metoprolol CR/XL improves systolic and diastolic left ventricular function in patients with chronic heart failure. | Echocardiography (Mount Kisco, N.Y.) 20040401 |
| [Beta-blocker therapy in the management of malignant ventricular arrhythmia in patients with acute myocardial infarction]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040401 |
| Beta-blockers in heart failure: are pharmacological differences clinically important? | Heart failure reviews 20040401 |
| Pharmacokinetics and pharmacodynamics of beta blockers in heart failure. | Heart failure reviews 20040401 |
| Design and analysis of group sequential clinical trials with multiple primary endpoints. | Biometrics 20040301 |
| Which beta-blocker for heart failure? | American heart journal 20040201 |
| Has COMET solved the controversy as to whether carvedilol is better than metoprolol in heart failure? | Expert opinion on pharmacotherapy 20040101 |
| Metoprolol responding uveitis. | Eye (London, England) 20040101 |
| Carvedilol was more effective than metoprolol tartrate for lowering mortality in chronic heart failure. | ACP journal club 20040101 |
| Transdermal drug delivery systems of a beta blocker: design, in vitro, and in vivo characterization. | Drug delivery 20040101 |
| Nonselective versus selective beta-blockers in the management of chronic heart failure: clinical implications of the carvedilol or Metoprolol European Trial. | Reviews in cardiovascular medicine 20040101 |
| Predictive factors for an effective beta-blocker therapy in Chinese patients with congenital long QT syndrome: A multivariate regression analysis. | Experimental and clinical cardiology 20040101 |
| Aortic aneurysm and electroconvulsive therapy in elderly depressive patient. | The journal of ECT 20031201 |
| Dosage of beta-adrenergic blockers after myocardial infarction. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031201 |
| In heart failure, all beta-blockers are not necessarily equal. | Cleveland Clinic journal of medicine 20031201 |
| Radical mechanisms in the radiosterilization of metoprolol tartrate solutions. | Pharmaceutical research 20031201 |
| Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF. | American heart journal 20031001 |
| COMET: a proposed mechanism of action to explain the results and concerns about dose. | Lancet (London, England) 20030927 |
| COMET: a proposed mechanism of action to explain the results and concerns about dose. | Lancet (London, England) 20030927 |
| A study on the release mechanism of drugs from hydrophilic partially coated perforated matrices. | Farmaco (Societa chimica italiana : 1989) 20030901 |
| How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). | Cardiac electrophysiology review 20030901 |
| Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failure. | Circulation 20030826 |
| Metoprolol CR/XL in black patients with heart failure (from the Metoprolol CR/XL randomized intervention trial in chronic heart failure). | The American journal of cardiology 20030815 |
| Immediate- vs extended-release metoprolol in heart failure. | The Journal of family practice 20030801 |
| Clinical trials update from the European Society of Cardiology Heart Failure meeting: COMET, COMPANION, Tezosentan and SHAPE. | European journal of heart failure 20030801 |
| Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation. | Circulation 20030715 |
| Matrix type transdermal drug delivery systems of metoprolol tartrate: in vitro characterization. | Acta pharmaceutica (Zagreb, Croatia) 20030601 |
| Extended-release metoprolol succinate in chronic heart failure. | The Annals of pharmacotherapy 20030501 |
| Enantiomeric separation of beta-blockers by HPLC using (R)-1-naphthylglycine and 3,5-dinitrobenzoic acid as chiral stationary phase. | Journal of pharmaceutical and biomedical analysis 20030410 |
| [Antihypertensive first-line and add-on treatment with a fixed controlled release combination of metoprololsuccinate/hydrochlorothiazide. Prospective doctor's office observational study in 14,964 patients]. | MMW Fortschritte der Medizin 20030403 |
| Pharmacokinetic considerations of formulation: extended-release metoprolol succinate in the treatment of heart failure. | Journal of cardiovascular pharmacology 20030201 |
| Sodium alginate microspheres of metoprolol tartrate for intranasal systemic delivery: development and evaluation. | Drug delivery 20030101 |
| [Effect of metoprolol CR/XL on remodeling of the heart and cardiac rhythm disturbances after myocardial infarction in patients with chronic heart failure]. | Kardiologiia 20030101 |
| [Effect of beta-blockers metoprolol CR/XL and carvedilol on left ventricular contractility in patients with chronic low cardiac output]. | Terapevticheskii arkhiv 20030101 |
| [Metoprolol CR/XL: advanced formulation of a classical beta-blocker]. | Kardiologiia 20030101 |
| [Antihypertensive first-line and add-on treatment with a fixed controlled release combination of metoprololsuccinate/hydrochlorothiazide. Prospective doctor's office observational study in 14,964 patients]. | Fortschritte der Medizin. Originalien 20030101 |
| Effects of long-term monotherapy with metoprolol CR/XL on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure. | Cardiovascular drugs and therapy 20020901 |
| Influence of complex solubility on formulations based on lambda carrageenan and basic drugs. | AAPS PharmSciTech 20020901 |
| Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF). | Journal of the American College of Cardiology 20020807 |
| A three-layer guar gum matrix tablet for oral controlled delivery of highly soluble metoprolol tartrate. | International journal of pharmaceutics 20020725 |
| Successful blood pressure control in the African American Study of Kidney Disease and Hypertension. | Archives of internal medicine 20020722 |
| Rationale and design of the carvedilol or metoprolol European trial in patients with chronic heart failure: COMET. | European journal of heart failure 20020601 |
| Novel metrics to compare dissolution profiles. | Pharmaceutical development and technology 20020501 |
| Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). | Circulation 20020402 |
| Gateways to Clinical Trials. | Methods and findings in experimental and clinical pharmacology 20020401 |
| Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). | Circulation 20020312 |
| Effect of controlled release/extended release metoprolol on carotid intima-media thickness in patients with hypercholesterolemia: a 3-year randomized study. | Stroke 20020201 |
| Effects of metoprolol CR/XL on mortality and hospitalizations in patients with heart failure and history of hypertension. | Journal of cardiac failure 20020201 |
| Longitudinal myocardial contraction improves early during titration with metoprolol CR/XL in patients with heart failure. | Heart (British Cardiac Society) 20020101 |
| [Complex assessment of efficacy and tolerance of metoprolol CR/ZOK in treating hypertension]. | Terapevticheskii arkhiv 20020101 |
| pH-metric solubility. 3. Dissolution titration template method for solubility determination. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011201 |
| Acute precipitants of congestive heart failure exacerbations. | Archives of internal medicine 20011022 |
| Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study. | Journal of the American College of Cardiology 20011001 |
| Study of formulation parameters by factorial design in metoprolol tartrate matrix systems. | Drug development and industrial pharmacy 20011001 |
| Cost-effectiveness of beta-blocker therapy with metoprolol or with carvedilol for treatment of heart failure in Canada. | American heart journal 20010901 |
| Enantiomeric separation of metoprolol and alpha-hydroxymetoprolol by liquid chromatography and fluorescence detection using a chiral stationary phase. | Journal of chromatography. B, Biomedical sciences and applications 20010715 |
| Possible mechanism of regression of myocardial hypertrophy. | Bulletin of experimental biology and medicine 20010701 |
| Enantioselective determination of metoprolol and major metabolites in human urine by capillary electrophoresis. | Journal of chromatography. B, Biomedical sciences and applications 20010505 |
| Metoprolol-paroxetine interaction in human liver microsomes: stereoselective aspects and prediction of the in vivo interaction. | Drug metabolism and disposition: the biological fate of chemicals 20010501 |
| Metoprolol CR/XL in the treatment of chronic heart failure. | Pharmacotherapy 20010501 |
| Oxygen consumption in patients with hyperthyroidism before and after treatment with beta-blockade versus thyrostatic treatment: a prospective randomized study. | Annals of surgery 20010101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.