200,000+ products from a single source!
sales@angenechem.com
Home > Imidazoles > 80498-67-5
80498-67-5 | 2-[4-[5-[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pentoxy]phenyl]-4,5-dihydro-1H-imidazole
CAS No: 80498-67-5 Catalog No: AG0059M9 MDL No:
Product Description
Catalog Number:
AG0059M9
Chemical Name:
2-[4-[5-[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pentoxy]phenyl]-4,5-dihydro-1H-imidazole
CAS Number:
80498-67-5
Molecular Formula:
C23H28N4O2
Molecular Weight:
392.4940
IUPAC Name:
2-[4-[5-[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pentoxy]phenyl]-4,5-dihydro-1H-imidazole
InChI:
InChI=1S/C23H28N4O2/c1(2-16-28-20-8-4-18(5-9-20)22-24-12-13-25-22)3-17-29-21-10-6-19(7-11-21)23-26-14-15-27-23/h4-11H,1-3,12-17H2,(H,24,25)(H,26,27)
InChI Key:
OIXYPNVIRVOZFH-UHFFFAOYSA-N
SMILES:
C(CCOc1ccc(cc1)C1=NCCN1)CCOc1ccc(cc1)C1=NCCN1
Properties
Complexity:
501
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
392.221g/mol
Formal Charge:
0
Heavy Atom Count:
29
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
392.503g/mol
Monoisotopic Mass:
392.221g/mol
Rotatable Bond Count:
10
Topological Polar Surface Area:
67.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.6
Literature
| Title | Journal |
|---|---|
| Pharmacophore model for pentamidine analogs active against Plasmodium falciparum. | European journal of medicinal chemistry 20101201 |
| Pentamidine is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 receptors. | Annals of the New York Academy of Sciences 19990621 |
| 1,5-Bis(4-amidinophenoxy)pentane (pentamidine) is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 binding sites. | European journal of pharmacology 19980717 |
| The accumulation of pentamidine and the toxic effects of the drug, its selected analogues and metabolites on isolated alveolar cells. | Toxicology 19930604 |
| Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis. | Antimicrobial agents and chemotherapy 19900701 |
| Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia. | Antimicrobial agents and chemotherapy 19900601 |
| Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia. | Journal of medicinal chemistry 19900401 |
Related Products
© 2019 Angene International Limited. All rights Reserved.