CAS 78111-17-8 | Okadaic Acid | CAS Number 78111-17-8

Title	Journal
Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.	Toxicology letters 20180301
Whole genome mRNA transcriptomics analysis reveals different modes of action of the diarrheic shellfish poisons okadaic acid and dinophysis toxin-1 versus azaspiracid-1 in Caco-2 cells.	Toxicology in vitro : an international journal published in association with BIBRA 20180201
Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.	Archives of toxicology 20170601
Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells.	Molecular neurobiology 20170101
Differences in metabolism of the marine biotoxin okadaic acid by human and rat cytochrome P450 monooxygenases.	Archives of toxicology 20160801
A mollusk VDR/PXR/CAR-like (NR1J) nuclear receptor provides insight into ancient detoxification mechanisms.	Aquatic toxicology (Amsterdam, Netherlands) 20160501
Hydroxyflutamide affects connexin 43 via the activation of PI3K/Akt-dependent pathway but has no effect on the crosstalk between PI3K/Akt and ERK1/2 pathways at the Raf-1 kinase level in primary rat Sertoli cells.	Toxicology in vitro : an international journal published in association with BIBRA 20160301
Dopamine D2 receptors' effects on renal inflammation are mediated by regulation of PP2A function.	American journal of physiology. Renal physiology 20160115
Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons.	PloS one 20160101
A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.	Archives of toxicology 20151201
Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150901
Microvascular dysfunction with increased vascular leakage response in mice systemically exposed to arsenic.	Cardiovascular toxicology 20140901
PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a.	Chemico-biological interactions 20140805
CYP3A4 activity reduces the cytotoxic effects of okadaic acid in HepaRG cells.	Archives of toxicology 20140801
Active elimination of the marine biotoxin okadaic acid by P-glycoprotein through an in vitro gastrointestinal barrier.	Toxicology letters 20140303
Modulation of albumin-induced endoplasmic reticulum stress in renal proximal tubule cells by upregulation of mapk phosphatase-1.	Chemico-biological interactions 20131025
Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.	Toxicology and applied pharmacology 20131001
The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in T-cells from controls and systemic lupus erythematosus patients.	The Journal of biological chemistry 20130726
The marine toxin okadaic acid induces alterations in the expression level of cancer-related genes in human neuronal cells.	Ecotoxicology and environmental safety 20130601
Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human.	Blood 20130418
Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20130401
Comparative toxicological study of the novel protein phosphatase inhibitor 19-Epi-okadaic acid in primary cultures of rat cerebellar cells.	Toxicological sciences : an official journal of the Society of Toxicology 20130401
RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase Iα.	Cellular signalling 20130301
Study of cytoskeletal changes induced by okadaic acid in HL-7702 liver cells and development of a fluorimetric microplate assay for detecting diarrhetic shellfish poisoning.	Environmental toxicology 20130201
Algal toxins and reverse osmosis desalination operations: laboratory bench testing and field monitoring of domoic acid, saxitoxin, brevetoxin and okadaic acid.	Water research 20121201
Sucrose synthase activity and carbohydrates content in relation to phosphorylation status of Vicia faba root meristems during reactivation from sugar depletion.	Journal of plant physiology 20121101
Cytotoxicity of yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.	Toxicon : official journal of the International Society on Toxinology 20121101
Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route.	Toxicon : official journal of the International Society on Toxinology 20121001
Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid-induced neurodegeneration model.	International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20121001
MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding.	The New phytologist 20121001
Effects of okadaic acid on haemocytes from Mytilus galloprovincialis: a comparison between field and laboratory studies.	Marine environmental research 20121001
Annexin A9 is a periplakin interacting partner in membrane-targeted cytoskeletal linker protein complexes.	FEBS letters 20120921
Automated flow-through amperometric immunosensor for highly sensitive and on-line detection of okadaic acid in mussel sample.	Talanta 20120915
Okadaic acid induced neurotoxicity leads to central cholinergic dysfunction in rats.	European journal of pharmacology 20120905
Toxins in mussels (Mytilus galloprovincialis) associated with diarrhetic shellfish poisoning episodes in China.	Toxicon : official journal of the International Society on Toxinology 20120901
Isolation and characterization of an enzyme from the Greenshell™ mussel Perna canaliculus that hydrolyses pectenotoxins and esters of okadaic acid.	Toxicon : official journal of the International Society on Toxinology 20120901
Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.	Journal of lipid research 20120901
Elucidation of the mass fragmentation pathways of the polyether marine toxins, dinophysistoxins, and identification of isomer discrimination processes.	Rapid communications in mass spectrometry : RCM 20120830
Occurrence of diarrhetic shellfish poisoning (DSP) toxins in clams (Ruditapes decussatus) from Tunis north lagoon.	Environmental monitoring and assessment 20120801
Cooling-increased phospho-β-arrestin-1 and β-arrestin-1 expression levels in 3T3-L1 adipocytes.	Cryobiology 20120801
Susceptibility of different mice strains to okadaic acid, a diarrhetic shellfish poisoning toxin.	Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120801
A protein phosphatase 2A catalytic subunit modulates blue light-induced chloroplast avoidance movements through regulating actin cytoskeleton in Arabidopsis.	Plant & cell physiology 20120801
Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.	Bioscience reports 20120801
Effects of ginkgolide A on okadaic acid-induced tau hyperphosphorylation and the PI3K-Akt signaling pathway in N2a cells.	Planta medica 20120801
Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells.	The Journal of biological chemistry 20120727
The structures of three metabolites of the algal hepatotoxin okadaic acid produced by oxidation with human cytochrome P450.	Bioorganic & medicinal chemistry 20120615
Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo.	International journal of molecular medicine 20120601
Highly sensitive detection of alkaline phosphatase using molecular beacon probes based on enzymatic polymerization.	Molecular and cellular probes 20120601
Auxin activates the plasma membrane H+-ATPase by phosphorylation during hypocotyl elongation in Arabidopsis.	Plant physiology 20120601
A study on neuroinflammatory marker in brain areas of okadaic acid (ICV) induced memory impaired rats.	Life sciences 20120522
Increased phosphorylation of dynamin-related protein 1 and mitochondrial fission in okadaic acid-treated neurons.	Brain research 20120515
Okadaic acid-sensitive phosphatase is related to MII/G1 transition in mouse oocytes.	Zygote (Cambridge, England) 20120501
PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Single laboratory validation of a ready-to-use phosphatase inhibition assay for detection of okadaic acid toxins.	Toxins 20120501
Development of a novel label-free amperometric immunosensor for the detection of okadaic acid.	Analytica chimica acta 20120429
Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425
Quantitative proteomic analysis of okadaic acid treated mouse small intestines reveals differentially expressed proteins involved in diarrhetic shellfish poisoning.	Journal of proteomics 20120403
Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation.	Journal of biochemistry 20120401
Phosphorylation status of matrix metalloproteinase 2 in myocardial ischaemia-reperfusion injury.	Heart (British Cardiac Society) 20120401
Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data.	Journal of separation science 20120401
Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase.	The Journal of biological chemistry 20120323
A screening lateral flow immunochromatographic assay for on-site detection of okadaic acid in shellfish products.	Analytical biochemistry 20120315
Comparative study of toxicological and cell cycle effects of okadaic acid and dinophysistoxin-2 in primary rat hepatocytes.	Life sciences 20120310
Chromatin specialization in bivalve molluscs: a leap forward for the evaluation of Okadaic Acid genotoxicity in the marine environment.	Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301
Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.	European journal of immunology 20120301
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.	Neurobiology of disease 20120301
Activation of MAP kinase family members triggered by TPA or ionomycin occurs via the protein phosphatase 4 pathway in Jurkat leukemia T cells.	Molecular medicine reports 20120301
[PP2A is involved in the inhibitory effect of progesterone on proliferation of mouse endometrial epithelial cells].	Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301
[Simultaneous determination of okadaic acid, dinophysistoxin, pectenotoxin and yessotoxin in shellfish by liquid chromatography-tandem mass spectrometry].	Se pu = Chinese journal of chromatography 20120301
Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222
Controlled release of drugs from gradient hydrogels for high-throughput analysis of cell-drug interactions.	Analytical chemistry 20120207
Activation of a tunicate (Ciona intestinalis) xenobiotic receptor orthologue by both natural toxins and synthetic toxicants.	Toxicon : official journal of the International Society on Toxinology 20120201
Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia.	Behavioural brain research 20120115
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.	Nature neuroscience 20120108
Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling.	British journal of pharmacology 20120101
The effect of okadaic acid on meiotic maturation of canine oocytes of different size.	Theriogenology 20120101
A simple colorimetric enzymatic-assay for okadaic acid detection based on the immobilization of protein phosphatase 2A in sol-gel.	Applied biochemistry and biotechnology 20120101
Okadaic acid inhibits cell growth and photosynthetic electron transport in the alga Dunaliella tertiolecta.	The Science of the total environment 20120101
Conjugation of genetically engineered protein phosphatases to magnetic particles for okadaic acid detection.	Journal of biotechnology 20120101
Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization.	BMC genomics 20120101
Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.	Marine drugs 20120101
Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137.	PloS one 20120101
[Effect of inhibitors serine/threonine protein kinases and protein phosphatases on mitosis progression of synchronized tobacco by-2 cells].	TSitologiia i genetika 20120101
Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure.	Journal of toxicology and environmental health. Part A 20120101
Okadaic acid and dinophysis toxin 2 have differential toxicological effects in hepatic cell lines inducing cell cycle arrest, at G0/G1 or G2/M with aberrant mitosis depending on the cell line.	Archives of toxicology 20111201
Mitochondrial dysfunction: a crucial event in okadaic acid (ICV) induced memory impairment and apoptotic cell death in rat brain.	Pharmacology, biochemistry, and behavior 20111201
Microcystin congener- and concentration-dependent induction of murine neuron apoptosis and neurite degeneration.	Toxicological sciences : an official journal of the Society of Toxicology 20111201
Okadaic acid induces apoptosis through the PKR, NF-κB and caspase pathway in human osteoblastic osteosarcoma MG63 cells.	Toxicology in vitro : an international journal published in association with BIBRA 20111201
Two ancient bacterial-like PPP family phosphatases from Arabidopsis are highly conserved plant proteins that possess unique properties.	Plant physiology 20111201
Okadaic acid and microcystin insensitive PPP-family phosphatases may represent novel biotechnology targets.	Plant signaling & behavior 20111201
Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.	Toxicology letters 20111130
Food poisoning outbreaks linked to mussels contaminated with okadaic acid and ester dinophysistoxin-3 in France, June 2009.	Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20111117
Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt.	Oncogene 20111103
K252a-sensitive protein kinases but not okadaic acid-sensitive protein phosphatases regulate methyl jasmonate-induced cytosolic Ca2+ oscillation in guard cells of Arabidopsis thaliana.	Journal of plant physiology 20111101
The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons.	Journal of neuroscience research 20111101
Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-terminal kinase pathway.	European journal of cancer (Oxford, England : 1990) 20111101
Protective effects of ginsenoside Rd against okadaic acid-induced neurotoxicity in vivo and in vitro.	Journal of ethnopharmacology 20111031
Hydroxytyrosol induces vascular smooth muscle cells apoptosis through NO production and PP2A activation with subsequent inactivation of Akt.	Planta medica 20111001
Integration of a pump and an electrical sensor into a membrane-based PDMS microbioreactor for cell culture and drug testing.	Biomedical microdevices 20111001
Development of an efficient protein phosphatase-based colorimetric test for okadaic acid detection.	Analytica chimica acta 20110930
Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling.	The Journal of biological chemistry 20110923
Co-pathological connected primary neurons in a microfluidic device for Alzheimer studies.	Biotechnology and bioengineering 20110901
Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.	Bone 20110901
Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation.	Toxicological sciences : an official journal of the Society of Toxicology 20110901
Adrenergic regulation of the distribution of transducer of regulated cAMP-response element-binding protein (TORC2) in rat pinealocytes.	Endocrinology 20110901
Sp1 is a transcription repressor to stanniocalcin-1 expression in TSA-treated human colon cancer cells, HT29.	Journal of cellular biochemistry 20110801
Effect of uncontrolled factors in a validated liquid chromatography-tandem mass spectrometry method question its use as a reference method for marine toxins: major causes for concern.	Analytical chemistry 20110801
Production of monoclonal antibody and application in indirect competitive ELISA for detecting okadaic acid and dinophytoxin-1 in seafood.	Environmental science and pollution research international 20110801
An electrochemical immunosensor based on covalent immobilization of okadaic acid onto screen printed carbon electrode via diazotization-coupling reaction.	Talanta 20110715
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.	European journal of medicinal chemistry 20110601
First report on the detection of pectenotoxin groups in Chinese shellfish by LC-MS/MS.	Toxicon : official journal of the International Society on Toxinology 20110601
Okadaic acid induces morphological changes, apoptosis and cell cycle alterations in different human cell types.	Journal of environmental monitoring : JEM 20110601
[Influence of PP2A activator on proliferation of HL-60 cells and analysis of PP2A activity changes in patients with acute myeloid leukemia].	Zhongguo shi yan xue ye xue za zhi 20110601
PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway.	Cancer letters 20110528
Neurobiological aspects of Alzheimer's disease.	Expert opinion on therapeutic targets 20110501
Induction of oxidative DNA damage by the marine toxin okadaic acid depends on human cell type.	Toxicon : official journal of the International Society on Toxinology 20110501
Protein phosphatase 2A B55 and A regulatory subunits interact with nitrate reductase and are essential for nitrate reductase activation.	Plant physiology 20110501
Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.	The Journal of biological chemistry 20110422
Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation.	The Journal of biological chemistry 20110415
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.	The Journal of biological chemistry 20110408
Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401
Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.	Journal of cellular biochemistry 20110401
Esterification of okadaic acid in the mussel Mytilus galloprovincialis.	Toxicon : official journal of the International Society on Toxinology 20110401
Enzyme-linked immunosensor based on super paramagnetic nanobeads for easy and rapid detection of okadaic acid.	Analytica chimica acta 20110401
The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.	The Journal of biological chemistry 20110225
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.	Apoptosis : an international journal on programmed cell death 20110201
Microencapsulation of okadaic acid as a tool for studying the accumulation of DSP toxins in mussels.	Marine environmental research 20110201
Analysis of the passage of the marine biotoxin okadaic acid through an in vitro human gut barrier.	Toxicology 20110111
Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells.	Cellular signalling 20110101
Results of a European interlaboratory method validation study for the quantitative determination of lipophilic marine biotoxins in raw and cooked shellfish based on high-performance liquid chromatography-tandem mass spectrometry. Part I: collaborative study.	Analytical and bioanalytical chemistry 20110101
Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development.	Anti-cancer agents in medicinal chemistry 20110101
Characterization of apoptotic changes induced by yessotoxin in the Bel7402 human hepatoma cell line.	Molecular medicine reports 20110101
BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.	PloS one 20110101
LC-MS/MS analysis of diarrhetic shellfish poisoning (DSP) toxins, okadaic acid and dinophysistoxin analogues, and other lipophilic toxins.	Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101
Evaluation of genotoxicity in gills and hemolymph of clam Ruditapes decussatus fed with the toxic dinoflagellate Prorocentrum lima.	Journal of toxicology and environmental health. Part A 20110101
Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and γH2AX analysis.	Journal of toxicology and environmental health. Part A 20110101
[Reconstruction of spatial structure of plant protein phosphatase type-1 and -2A in complex with okadaic acid].	TSitologiia i genetika 20110101
Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B.	PloS one 20110101
Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.	PloS one 20110101
Enzyme-linked immunosorbent assay for okadaic acid: investigation of analytical conditions and sample matrix on assay performance.	Journal of AOAC International 20110101
Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma.	PloS one 20110101
Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.	The Journal of biological chemistry 20101224
Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation.	Cellular signalling 20101201
Strategies for the elimination of matrix effects in the liquid chromatography tandem mass spectrometry analysis of the lipophilic toxins okadaic acid and azaspiracid-1 in molluscan shellfish.	Journal of chromatography. A 20101105
An okadaic acid-induced model of tauopathy and cognitive deficiency.	Brain research 20101104
Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids.	Functional & integrative genomics 20101101
Binding of diarrheic shellfish poisoning toxins to okadaic acid binding proteins purified from the sponge Halichondria okadai.	Bioorganic & medicinal chemistry 20101101
Mediterranean mussel gene expression profile induced by okadaic acid exposure.	Environmental science & technology 20101101
Protein phosphatase 1γ is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage.	EMBO reports 20101101
Lily Cdc42/Rac-interactive binding motif-containing protein, a Rop target, involves calcium influx and phosphoproteins during pollen germination and tube growth.	Plant signaling & behavior 20101101
Formal total synthesis of okadaic acid via regiocontrolled gold(I)-catalyzed spiroketalizations.	Organic letters 20101015
Corozalic acid: a key okadaic acid biosynthetic precursor with phosphatase inhibition activity.	Chemistry (Weinheim an der Bergstrasse, Germany) 20101011
Differential contribution of the MTOR and MNK pathways to the regulation of mRNA translation in meiotic and postmeiotic mouse male germ cells.	Biology of reproduction 20101001
A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.	Biochimica et biophysica acta 20101001
Decreased activity of the Na+/H+ exchanger by phosphodiesterase 5A inhibition is attributed to an increase in protein phosphatase activity.	Hypertension (Dallas, Tex. : 1979) 20101001
[Effects of gensenoside Rg1 on tau protein phosphorylation induced by okadaic acid in rat brain slices].	Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20101001
Naturally contaminated shellfish samples: quantification of diarrhetic shellfish poisoning toxins in unhydrolysed and hydrolysed extracts and cytotoxicity assessment.	Journal of applied toxicology : JAT 20101001
Activation of eukaryotic initiation factor-2 α-kinases in okadaic acid-treated neurons.	Neuroscience 20100915
Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1.	Neurochemistry international 20100901
The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau.	Journal of neurochemistry 20100901
Phosphorylation of the CREB-specific coactivator TORC2 at Ser(307) regulates its intracellular localization in COS-7 cells and in the mouse liver.	American journal of physiology. Endocrinology and metabolism 20100901
Effect of PP-2A on neurite outgrowth in neuronal cells.	In vitro cellular & developmental biology. Animal 20100901
Dinoflagellate polyether within the yessotoxin, pectenotoxin and okadaic acid toxin groups: characterization, analysis and human health implications.	Toxicon : official journal of the International Society on Toxinology 20100815
Intra-amygdalar okadaic acid enhances conditioned taste aversion learning and CREB phosphorylation in rats.	Brain research 20100812
Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons.	Journal of neurochemistry 20100801
Visualization of the interaction between Gbetagamma and tubulin during light-induced cell elongation of Blepharisma japonicum.	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100801
Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner.	Brain research 20100723
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.	Journal of medicinal chemistry 20100722
Assessment of okadaic acid effects on cytotoxicity, DNA damage and DNA repair in human cells.	Mutation research 20100707
Kinases and phosphatases in ischaemic preconditioning: a re-evaluation.	Basic research in cardiology 20100701
Regulation of postsynaptic gephyrin cluster size by protein phosphatase 1.	Molecular and cellular neurosciences 20100701
PhosphoMARCKS drives motility of mouse melanoma cells.	Cellular signalling 20100701
Biodosimetry for high dose accidental exposures by drug induced premature chromosome condensation (PCC) assay.	Mutation research 20100617
Effects of toxic and non-toxic blue mussel meal on health and product quality of laying hens.	Journal of animal physiology and animal nutrition 20100601
First U.S. report of shellfish harvesting closures due to confirmed okadaic acid in Texas Gulf coast oysters.	Toxicon : official journal of the International Society on Toxinology 20100601
A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.	Molecular endocrinology (Baltimore, Md.) 20100601
Development of ELISAs for detecting domoic acid, okadaic acid, and saxitoxin and their applicability for the detection of marine toxins in samples collected in Belgium.	Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601
Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.	Molecular cancer research : MCR 20100601
First evidence of Okadaic acid acyl-derivative and Dinophysistoxin-3 in mussel samples collected in Chiloe Island, Southern Chile.	The Journal of toxicological sciences 20100601
Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity.	Hematology (Amsterdam, Netherlands) 20100601
Ser123 is essential for the water channel activity of McPIP2;1 from Mesembryanthemum crystallinum.	The Journal of biological chemistry 20100528
Acute regulation of renal Na+/H+ exchanger NHE3 by dopamine: role of protein phosphatase 2A.	American journal of physiology. Renal physiology 20100501
Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal.	Stem cells (Dayton, Ohio) 20100501
[Protective effects of IGF-1 on cell injuries and tau hyperphosphorylation induced by okadaic acid].	Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100501
Comparative study of various immune parameters in three bivalve species during a natural bloom of Dinophysis acuminata in Santa Catarina Island, Brazil.	Toxins 20100501
Maintained activity of glycogen synthase kinase-3beta despite of its phosphorylation at serine-9 in okadaic acid-induced neurodegenerative model.	Biochemical and biophysical research communications 20100430
Determination of okadaic acid, dinophysistoxin-1 and related esters in Greek mussels using HPLC with fluorometric detection, LC-MS/MS and mouse bioassay.	Toxicon : official journal of the International Society on Toxinology 20100401
Okadaic acid induces apoptosis in Down syndrome fibroblasts.	Toxicology in vitro : an international journal published in association with BIBRA 20100401
Embryotoxic effects of the marine biotoxin okadaic acid on murine embryonic stem cells.	Toxicon : official journal of the International Society on Toxinology 20100401
cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes.	Journal of molecular and cellular cardiology 20100401
Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.	Proteomics 20100401
Encystation process of Giardia lamblia: morphological and regulatory aspects.	Archives of microbiology 20100401
Inhibition of Ser/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors.	The Journal of biological chemistry 20100312
Comparison of gene expression profiles in BALB/c 3T3 transformed foci exposed to tumor promoting agents.	Toxicology in vitro : an international journal published in association with BIBRA 20100301
NG108-15 cell-based and protein phosphatase inhibition assays as alternative semiquantitative tools for the screening of lipophilic toxins in mussels. Okadaic acid detection.	Toxicology in vitro : an international journal published in association with BIBRA 20100301
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.	Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301
Dynamic regulation of guard cell anion channels by cytosolic free Ca2+ concentration and protein phosphorylation.	The Plant journal : for cell and molecular biology 20100301
NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.	American journal of physiology. Renal physiology 20100301
High-sensitive flow-based kinetic exclusion assay for okadaic acid assessment in shellfish samples.	Biosensors & bioelectronics 20100215
Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors.	The Journal of biological chemistry 20100212
Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues.	Apoptosis : an international journal on programmed cell death 20100201
Requirement for proteolysis in spindle assembly checkpoint silencing.	Cell cycle (Georgetown, Tex.) 20100201
Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity.	Brain research 20100114
CLA reduces breast cancer cell growth and invasion through ERalpha and PI3K/Akt pathways.	Chemico-biological interactions 20100105
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia.	Toxicon : official journal of the International Society on Toxinology 20100101
Subcellular distribution of okadaic acid in the digestive gland of Mytilus galloprovincialis: first evidences of lipoprotein binding to okadaic acid.	Toxicon : official journal of the International Society on Toxinology 20100101
Decrease of marine toxin content in bivalves by industrial processes.	Toxicon : official journal of the International Society on Toxinology 20100101
Complex toxin profile of Mytilus galloprovincialis from the Adriatic sea revealed by LC-MS.	Toxicon : official journal of the International Society on Toxinology 20100101
Profiles of fatty acids and 7-O-acyl okadaic acid esters in bivalves: can bacteria be involved in acyl esterification of okadaic acid?	Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100101
The algal hepatoxoxin okadaic acid is a substrate for human cytochromes CYP3A4 and CYP3A5.	Toxicon : official journal of the International Society on Toxinology 20100101
Interactive role of protein phosphatase 2A and protein kinase Calpha in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery.	Journal of vascular research 20100101
Identification of okadaic acid production in the marine dinoflagellate Prorocentrum rhathymum from Florida Bay.	Toxicon : official journal of the International Society on Toxinology 20100101
Synergistic interactions between sorafenib and bortezomib in hepatocellular carcinoma involve PP2A-dependent Akt inactivation.	Journal of hepatology 20100101
Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells.	The FEBS journal 20100101
The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytes.	British journal of pharmacology 20100101
Polyketides from marine dinoflagellates of the genus Prorocentrum, biosynthetic origin and bioactivity of their okadaic acid analogues.	Mini reviews in medicinal chemistry 20100101
Acetyl-L-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats.	Journal of Alzheimer's disease : JAD 20100101
Targets and effects of yessotoxin, okadaic acid and palytoxin: a differential review.	Marine drugs 20100101
Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway.	PloS one 20100101
Increment of activated serine/threonine protein phosphatase in brain membrane fraction synchronized with antinociceptive effect of morphine in mice.	Biological & pharmaceutical bulletin 20100101
Mechanisms of hyposmotic volume regulation in isolated nematocytes of the anthozoan Aiptasia diaphana.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Phosphodiesterase 5A inhibition decreases NHE-1 activity without altering steady state pH(i): role of phosphatases.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
PP2A inhibition assay using recombinant enzyme for rapid detection of okadaic acid and its analogs in shellfish.	Toxins 20100101
Development and single-laboratory validation of a pseudofunctional biosensor immunoassay for the detection of the okadaic acid group of toxins.	Analytical chemistry 20091215
Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice.	Cardiovascular research 20091201
Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin.	Toxicology and applied pharmacology 20091201
Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin-proteasome system in PC12D cells.	Journal of neural transmission (Vienna, Austria : 1996) 20091201
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A.	Nature structural & molecular biology 20091201
Complex phosphatase regulation of Ca2+-activated Cl- currents in pulmonary arterial smooth muscle cells.	The Journal of biological chemistry 20091120
A structural basis for the reduced toxicity of dinophysistoxin-2.	Chemical research in toxicology 20091101
Phosphorylation of human enhancer of filamentation (HEF1) on serine 369 induces its proteasomal degradation.	Biochemical pharmacology 20091015
Tau hyperphosphorylation affects Smad 2/3 translocation.	Neuroscience 20091006
Morphological and biochemical changes associated with apoptosis induced by okadaic acid in human amniotic FL cells.	Environmental toxicology 20091001
Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells.	International immunopharmacology 20091001
Expression of the genes siamois, engrailed-2, bmp4 and myf5 during Xenopus development in presence of the marine toxins okadaic acid and palytoxin.	Chemosphere 20091001
Protein phosphatase activity and sucrose-mediated induction of fructan synthesis in wheat.	Planta 20091001
PKA mediates constitutive activation of CFTR in human sweat duct.	The Journal of membrane biology 20091001
Greatwall maintains mitosis through regulation of PP2A.	The EMBO journal 20090916
Development of a monoclonal antibody binding okadaic acid and dinophysistoxins-1, -2 in proportion to their toxicity equivalence factors.	Toxicon : official journal of the International Society on Toxinology 20090915
Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases.	Oncogene 20090910
Ocadaic acid retains caveolae in multicaveolar clusters.	Pathology oncology research : POR 20090901
Pin1 affects Tau phosphorylation in response to Abeta oligomers.	Molecular and cellular neurosciences 20090901
Functional study of the effect of phosphatase inhibitors on KCNQ4 channels expressed in Xenopus oocytes.	Acta pharmacologica Sinica 20090901
PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation.	The Journal of biological chemistry 20090821
Nicotine combined with okadaic acid or taxol adversely affects bovine oocyte maturation and subsequent embryo development.	Fertility and sterility 20090801
Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast.	Toxicon : official journal of the International Society on Toxinology 20090801
A novel dephosphorylation-activated conductance in a mouse renal collecting duct cell line.	Experimental physiology 20090801
Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.	Molecular pharmacology 20090801
Phosphatase inhibition and cell survival after DNA damage induced by radiation.	Cancer biology & therapy 20090801
Differential inhibition of single and cluster type tumor cell migration.	Anticancer research 20090801
Insulin action on polyunsaturated phosphatidic acid formation in rat brain: an 'in vitro' model with synaptic endings from cerebral cortex and hippocampus.	Neurochemical research 20090701
The N-terminal domain influences the structure and property of protein phosphatase 1.	Molecular and cellular biochemistry 20090701
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.	British journal of pharmacology 20090701
Failure of Ca2+-activated, CREB-dependent transcription in astrocytes.	Glia 20090601
Temperature and base requirements for the alkaline hydrolysis of okadaite's esters.	Toxicon : official journal of the International Society on Toxinology 20090601
First evidence of okadaic acid in Mytilus galloprovincialis mussels, collected in a Mediterranean Lagoon, Tunisia.	Bulletin of environmental contamination and toxicology 20090601
Insulin induced alteration in post-translational modifications of histone H3 under a hyperglycemic condition in L6 skeletal muscle myoblasts.	Biochimica et biophysica acta 20090601
Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixture.	Chemical research in toxicology 20090601
Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53.	Cell cycle (Georgetown, Tex.) 20090601
Sensitive method for the determination of lipophilic marine biotoxins in extracts of mussels and processed shellfish by high-performance liquid chromatography-tandem mass spectrometry based on enrichment by solid-phase extraction.	Journal of chromatography. A 20090522
An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells.	Lab on a chip 20090521
Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells.	The Journal of biological chemistry 20090501
Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor.	Genes to cells : devoted to molecular & cellular mechanisms 20090501
PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.	Nature cell biology 20090501
Role of protein kinase C in regulation of Na+- and K +-dependent ATPase activity and pump function in corneal endothelial cells.	Japanese journal of ophthalmology 20090501
The total activity of a mixture of okadaic acid-group compounds can be calculated by those of individual analogues in a phosphoprotein phosphatase 2A assay.	Toxicon : official journal of the International Society on Toxinology 20090501
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.	The Journal of biological chemistry 20090424
Okadaic acid promotes angiogenesis via activation of hypoxia-inducible factor-1.	Cancer letters 20090408
Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.	Journal of cellular physiology 20090401
The mixed-lineage kinase DLK undergoes Src-dependent tyrosine phosphorylation and activation in cells exposed to vanadate or platelet-derived growth factor (PDGF).	Cellular signalling 20090401
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.	Cardiovascular research 20090401
In situ activities of hexokinase and fructokinase in relation to phosphorylation status of root meristem cells of Vicia faba during reactivation from sugar starvation.	Physiologia plantarum 20090401
Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis.	Genes to cells : devoted to molecular & cellular mechanisms 20090401
NNZ-2566: a Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke.	Journal of the neurological sciences 20090315
Quantitative interaction proteomics using mass spectrometry.	Nature methods 20090301
Serine/threonine protein phosphatases have no role in the inhibitory effects of low-frequency stimulation in perforant path kindling acquisition in rats.	Neuroscience letters 20090227
Drug-target identification from total cellular lysate by drug-induced conformational changes.	Analytical biochemistry 20090215
Multiple signal transduction pathways in okadaic acid induced apoptosis in HeLa cells.	Toxicology 20090204
Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A.	Brain research 20090203
The nonconserved N-terminus of protein phosphatase 2B confers its properties to protein phosphatase 1.	IUBMB life 20090201
Identification of tumor promotion marker genes for predicting tumor promoting potential of chemicals in BALB/c 3T3 cells.	Toxicology in vitro : an international journal published in association with BIBRA 20090201
A bienzyme electrochemical probe for flow injection analysis of okadaic acid based on protein phosphatase-2A inhibition: an optimization study.	Analytical biochemistry 20090201
Detection of okadaic acid and related esters in mussels during diarrhetic shellfish poisoning (DSP) episodes in Greece using the mouse bioassay, the PP2A inhibition assay and HPLC with fluorimetric detection.	Toxicon : official journal of the International Society on Toxinology 20090201
Mechanism of okadaic acid-induced neuronal death and the effect of estrogens.	Journal of neurochemistry 20090201
Assessment of a new lateral flow immunochromatographic (LFIC) assay for the okadaic acid group of toxins using naturally contaminated bivalve shellfish from the Portuguese coast.	Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090201
Extraction recoveries and stability of diarrhetic shellfish poisoning (DSP) toxins in naturally contaminated samples.	Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090201
The phosphatase inhibitor, okadaic acid, strongly protects primary rat cortical neurons from lethal oxygen-glucose deprivation.	Biochemical and biophysical research communications 20090116
Versatile synthesis of the C3-C14 domain of 7-deoxyokadaic acid.	The Journal of organic chemistry 20090116
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.	Experimental cell research 20090115
Okadaic acid protects human neuroblastoma SH-SY5Y cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis.	Neuroscience letters 20090109
Ubiquitination as a priming process of PKC alpha and PKC epsilon degradation in the alphaT3-1 gonadotrope cell line.	Neuroendocrinology 20090101
Identification of PP2A as a novel interactor and regulator of TRIP-Br1.	Cellular signalling 20090101
KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel.	Channels (Austin, Tex.) 20090101
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.	Progress in molecular and subcellular biology 20090101
Large-scale production of growing oocytes in vitro from neonatal mouse ovaries.	The International journal of developmental biology 20090101
Structure-Function analysis of the CTLA-4 interaction with PP2A.	BMC immunology 20090101
Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats.	Journal of Alzheimer's disease : JAD 20090101
In vitro micronucleus test in HepG2 transformants expressing a series of human cytochrome P450 isoforms with chemicals requiring metabolic activation.	Mutation research 20090101
The JNK pathway amplifies and drives subcellular changes in tau phosphorylation.	Neuropharmacology 20090101
[The effect of okadaic acid on root morphology of Arabidopsis thaliana and microtubule organization in its cells].	TSitologiia i genetika 20090101
Enhanced developmental potential of heat-shocked porcine parthenogenetic embryos is related to accelerated mitogen-activated protein kinase dephosphorylation.	Reproduction, fertility, and development 20090101
The nonconserved N-terminus of protein phosphatases 1 influences its active site.	BMB reports 20081231
First detection of Pectenotoxin-11 and confirmation of OA-D8 diol-ester in Dinophysis acuta from European waters by LC-MS/MS.	Toxicon : official journal of the International Society on Toxinology 20081215
Cellular distribution of okadaic acid in the digestive gland of Mytilus galloprovincialis (Lamarck, 1819).	Toxicon : official journal of the International Society on Toxinology 20081215
The complexity of signaling in host-pathogen interactions revealed by the Toxoplasma gondii-dependent modulation of JNK phosphorylation.	Experimental cell research 20081210
Enzymatic recycling-based amperometric immunosensor for the ultrasensitive detection of okadaic acid in shellfish.	Biosensors & bioelectronics 20081201
Assessment of protein phosphatase in a re-usable rapid assay format in detecting microcystins and okadaic acid as a precursor to biosensor development.	Toxicon : official journal of the International Society on Toxinology 20081201
Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins.	The FEBS journal 20081201
Marine toxins and the cytoskeleton.	The FEBS journal 20081201
Detection of diarrheic shellfish poisoning and azaspiracid toxins in Moroccan mussels: comparison of the LC-MS method with the commercial immunoassay kit.	Marine drugs 20081201
Soapwort saponins trigger clathrin-mediated endocytosis of saporin, a type I ribosome-inactivating protein.	Chemico-biological interactions 20081125
The relaxant effect of okadaic acid on canine basilar artery involves activation of PKCalpha and phosphorylation of the myosin light chain at Thr-9.	European journal of pharmacology 20081119
Okadaic acid increases autophagosomes in rat neurons: implications for Alzheimer's disease.	Journal of neuroscience research 20081101
Sympathetic nervous system modulates the ocular hypotensive action of MT2-melatonin receptors in normotensive rabbits.	Journal of pineal research 20081101
MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides.	American journal of physiology. Cell physiology 20081101
Protein markers of algal toxin contamination in shellfish.	Toxicon : official journal of the International Society on Toxinology 20081101
Cellular serine/threonine phosphatase activity during human cytomegalovirus infection.	Virology 20081025
New esters of okadaic acid in seawater and blue mussels (Mytilus edulis).	Journal of agricultural and food chemistry 20081022
Regulation of the meiotic prophase I to metaphase I transition in mouse spermatocytes.	Chromosoma 20081001
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.	Endocrinology 20081001
Enhancing memory formation by altering protein phosphorylation balance.	Neurobiology of learning and memory 20081001
[Effects of different phosphorus sources on the growth and toxin production of Prorocentrum lima].	Huan jing ke xue= Huanjing kexue 20081001
Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins.	Toxicon : official journal of the International Society on Toxinology 20080915
Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.	Journal of leukocyte biology 20080901
Attenuation of hypoosmotic stress-induced ANP secretion via I(Cl,swell) in renal hypertensive rat atria.	Peptides 20080901
Profiles and levels of fatty acid esters of okadaic acid group toxins and pectenotoxins during toxin depuration. Part II: blue mussels (Mytilus edulis) and flat oyster (Ostrea edulis).	Toxicon : official journal of the International Society on Toxinology 20080901
Profiles and levels of fatty acid esters of okadaic acid group toxins and pectenotoxins during toxin depuration. Part I: brown crab (Cancer pagurus).	Toxicon : official journal of the International Society on Toxinology 20080901
Roles of RCN1, regulatory A subunit of protein phosphatase 2A, in methyl jasmonate signaling and signal crosstalk between methyl jasmonate and abscisic acid.	Plant & cell physiology 20080901
Identification of 19-epi-okadaic acid, a new diarrhetic shellfish poisoning toxin, by liquid chromatography with mass spectrometry detection.	Marine drugs 20080901
beta-Secretase inhibitor increases amyloid-beta precursor protein level in rat brain cortical primary neurons induced by okadaic acid.	Chinese medical journal 20080805
Mass spectrometric analysis of the marine lipophilic biotoxins pectenotoxin-2 and okadaic acid by four different types of mass spectrometers.	Journal of mass spectrometry : JMS 20080801
Approaches to the evaluation of matrix effects in the liquid chromatography-mass spectrometry (LC-MS) analysis of three regulated lipophilic toxin groups in mussel matrix (Mytilus edulis).	Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080801
Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8.	The Journal of biological chemistry 20080718
Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1.	Oncogene 20080717
Age-related toxic effects and recovery from okadaic acid treatment in Enchytraeus crypticus (Annelida: Oligochaeta).	Toxicon : official journal of the International Society on Toxinology 20080701
In vivo influence of cyanobacterial toxins on enzyme activity and gene expression of protein phosphatases in Alfalfa (Medicago sativa).	Toxicon : official journal of the International Society on Toxinology 20080701
[Preparation and application of the monoclonal antibody against okadaic acid].	Wei sheng yan jiu = Journal of hygiene research 20080701
Inhibition of lipopolysaccharide-induced interleukin-1beta and tumor necrosis factor-alpha production by menthone through nuclear factor-kappaB signaling pathway in HaCat cells.	The Chinese journal of physiology 20080630
Epileptogenesis causes an N-methyl-d-aspartate receptor/Ca2+-dependent decrease in Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent epileptiform discharges.	European journal of pharmacology 20080624
The cytotoxicity and genotoxicity of okadaic acid are cell-line dependent.	Toxicon : official journal of the International Society on Toxinology 20080615
Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction.	Neurobiology of disease 20080601
[Effect of okadaic acid on differentiation of NB4 and MR2 cells induced by all-trans retinoic acid].	Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20080601
Dynein cleavage and microtubule accumulation in okadaic acid-treated neurons.	Neuroscience letters 20080530
Inhibition of protein phosphatases impairs the ability of astrocytes to detoxify hydrogen peroxide.	Free radical biology & medicine 20080515
Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels (Mytilus edulis).	Toxicon : official journal of the International Society on Toxinology 20080501
GSK-3 mediates the okadaic acid-induced modification of collapsin response mediator protein-2 in human SK-N-SH neuroblastoma cells.	Journal of cellular biochemistry 20080415
Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells.	Regulatory peptides 20080410
A DING phosphatase in Thermus thermophilus.	Amino acids 20080401
Novel rice OsSIPK is a multiple stress responsive MAPK family member showing rhythmic expression at mRNA level.	Planta 20080401
Assessment of the hydrolysis process for the determination of okadaic acid-group toxin ester: presence of okadaic acid 7-O-acyl-ester derivates in Spanish shellfish.	Toxicon : official journal of the International Society on Toxinology 20080401
Characterization of fatty acid esters of okadaic acid and related toxins in blue mussels (Mytilus edulis) from Norway.	Rapid communications in mass spectrometry : RCM 20080401
Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.	Molecular and cellular endocrinology 20080326
PP2A regulates the pro-apoptotic activity of FOXO1.	The Journal of biological chemistry 20080321
Studies of diarrhetic activity on pectenotoxin-6 in the mouse and rat.	Toxicon : official journal of the International Society on Toxinology 20080315
Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption.	Journal of cell science 20080315
Folate deprivation increases tau phosphorylation by homocysteine-induced calcium influx and by inhibition of phosphatase activity: Alleviation by S-adenosyl methionine.	Brain research 20080314
Okadaic acid-sensitive protein phosphatases constrain phrenic long-term facilitation after sustained hypoxia.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20080312
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation.	Current biology : CB 20080311
The phosphatase PHLPP controls the cellular levels of protein kinase C.	The Journal of biological chemistry 20080307
Accumulation and depuration of okadaic acid esters in the European green crab (Carcinus maenas) during a feeding study.	Toxicon : official journal of the International Society on Toxinology 20080301
Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators.	Molecular pharmacology 20080301
Induction of actin cytoskeleton rearrangement by methyl okadaate--comparison with okadaic acid.	The FEBS journal 20080301
Hsp27 decreases inclusion body formation from mutated GTP-cyclohydrolase I protein.	Biochimica et biophysica acta 20080301
Diverse bacterial PKS sequences derived from okadaic acid-producing dinoflagellates.	Marine drugs 20080301
Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis.	The Journal of biological chemistry 20080208
Differential expression of genes associated with cell proliferation and apoptosis induced by okadaic acid during the transformation process of BALB/c 3T3 cells.	Toxicology in vitro : an international journal published in association with BIBRA 20080201
mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.	The Journal of biological chemistry 20080201
Effects of the marine toxins okadaic acid and palytoxin on mussel phagocytosis.	Fish & shellfish immunology 20080201
Combined cytotoxicity and genotoxicity of a marine toxin and seafood contaminant metal ions (chromium and cadmium).	Environmental toxicology 20080201
Analysis of calcineurin activity by capillary electrophoresis with laser-induced fluorescence detection using peptide substrate.	Journal of separation science 20080201
Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.	The Journal of biological chemistry 20080125
Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.	FEBS letters 20080123
Potassium channels in hippocampal neurones are absent in a transgenic but not in a chemical model of Alzheimer's disease.	Brain research 20080123
Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau.	The Journal of biological chemistry 20080104
Shellfish consumption: a major risk factor for colorectal cancer.	Medical hypotheses 20080101
p38MAPK delta controls c-Myb degradation in response to stress.	Blood cells, molecules & diseases 20080101
Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A.	American journal of physiology. Gastrointestinal and liver physiology 20080101
PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment.	International journal of oncology 20080101
Analysis of meiotic prophase I in live mouse spermatocytes.	Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20080101
Neural stem cells improve learning and memory in rats with Alzheimer's disease.	Pathobiology : journal of immunopathology, molecular and cellular biology 20080101
Belizeanic acid: a potent protein phosphatase 1 inhibitor belonging to the okadaic acid class, with an unusual skeleton.	Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Postsynaptic signals mediating induction of long-term synaptic depression in the entorhinal cortex.	Neural plasticity 20080101
Intracellular processing of riboflavin in human breast cancer cells.	Molecular pharmaceutics 20080101
Ryegrass leaf fructan synthesis is oxygen dependent and abolished by endomembrane inhibitors.	The New phytologist 20080101
Involvement of protein phosphatase 2A in arsenic trioxide-induced differentiation and apoptosis of NB4 cells.	Methods and findings in experimental and clinical pharmacology 20080101
Vasopressin regulates the phosphorylation state of AMP-activated protein kinase (AMPK) in MDCK-C7 cells.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Downstream targets of altered sphingolipid metabolism in response to inhibition of ENOX2 by phenoxodiol.	BioFactors (Oxford, England) 20080101
GABA(A)-current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA(A) 'phasic' receptors.	Proceedings of the National Academy of Sciences of the United States of America 20071226
Anatomical distribution of diarrhetic shellfish poisoning (DSP) toxins in the mussel Mytilus galloprovincialis.	Toxicon : official journal of the International Society on Toxinology 20071215
Phosphatases regulate histamine synthesis in rat brain.	Neuroscience 20071212
Enzyme sensor for the electrochemical detection of the marine toxin okadaic acid.	Analytica chimica acta 20071212
Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20071212
Reduction of mint-1, mint-2, and APP overexpression in okadaic acid-treated neurons.	Neuroreport 20071203
PPARalpha and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK-HEP-1.	International journal of cancer 20071201
Extraction of microalgal toxins by large-scale pumping of seawater in Spain and Norway, and isolation of okadaic acid and dinophysistoxin-2.	Toxicon : official journal of the International Society on Toxinology 20071201
Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.	Cellular signalling 20071201
Differential involvement of reactive oxygen species in apoptosis caused by the inhibition of protein phosphatase 2A in Jurkat and CCRF-CEM human T-leukemia cells.	Experimental and molecular pathology 20071201
Phosphoprotein analysis for investigation of in vivo relationship between protein phosphatase inhibitory activities and acute hepatotoxicity of microcystin-LR.	Environmental toxicology 20071201
Chemical defenses: from compounds to communities.	The Biological bulletin 20071201
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.	Chemistry & biology 20071201
Activation of epidermal akt by diverse mouse skin tumor promoters.	Molecular cancer research : MCR 20071201
Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.	The Journal of biological chemistry 20071116
Myosin II and Rho kinase activity are required for melanosome aggregation in fish retinal pigment epithelial cells.	Cell motility and the cytoskeleton 20071101
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance.	The Journal of physiology 20071101
Cell growth inhibition by okadaic acid involves gut-enriched Kruppel-like factor mediated enhanced expression of c-Myc.	Cancer research 20071101
Effect of fetuin, a TGFbeta antagonist and pentoxifylline, a cytokine antagonist on hepatic stellate cell function and fibrotic parameters in fibrosis.	European journal of pharmacology 20071031
Self-assembly of okadaic acid as a pathway to the cell.	Organic letters 20071011
Isolation and characterization of okadaic acid binding proteins from the marine sponge Halichondria okadai.	Biochemistry 20071009
Occurrence and seasonal variations of algal toxins in water, phytoplankton and shellfish from North Stradbroke Island, Queensland, Australia.	Marine environmental research 20071001
Retinoic acid enhances differentiation of v-myb-transformed monoblasts induced by okadaic acid.	Leukemia research 20071001
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter.	Cancer research 20071001
Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis.	Nature 20070920
Identification and characterization of DTX-5c and 7-hydroxymethyl-2-methylene-octa-4,7-dienyl okadaate from Prorocentrum belizeanum cultures by LC-MS.	Toxicon : official journal of the International Society on Toxinology 20070915
Cytoplasmic linker protein-170 enhances spreading and phagocytosis in activated macrophages by stabilizing microtubules.	Journal of immunology (Baltimore, Md. : 1950) 20070915
Expression and function of protein phosphatase PP2A in malignant testicular germ cell tumours.	The Journal of pathology 20070901
Development of a novel immunobiosensor method for the rapid detection of okadaic acid contamination in shellfish extracts.	Analytical and bioanalytical chemistry 20070901
Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells.	Pharmacological research 20070901
[Protective effect of (-) clausenamide against neurotoxicity induced by okadaic acid and beta-amyloid peptide25-35].	Yao xue xue bao = Acta pharmaceutica Sinica 20070901
A fascination with 1,2-diacetals.	The Journal of organic chemistry 20070803
19-epi-okadaic acid, a novel protein phosphatase inhibitor with enhanced selectivity.	Organic letters 20070802
Apoptosis of human neutrophils induced by protein phosphatase 1/2A inhibition is caspase-independent and serine protease-dependent.	Journal of cellular physiology 20070801
Modulation of hippocampal calcium signalling and plasticity by serine/threonine protein phosphatases.	Journal of neurochemistry 20070801
Characterisation of okadaic acid related toxins by liquid chromatography coupled with mass spectrometry.	Toxicon : official journal of the International Society on Toxinology 20070801
Comparison of effects of PKA catalytic subunit on I(h) and calcium channel currents in rat dorsal root ganglion cells.	Biomedical research (Tokyo, Japan) 20070801
Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis.	Apoptosis : an international journal on programmed cell death 20070701
Lipophilic toxin profile in Galicia (Spain): 2005 toxic episode.	Toxicon : official journal of the International Society on Toxinology 20070615
Bidirectional synaptic plasticity at nociceptive afferents in the rat central amygdala.	The Journal of physiology 20070615
Toxicity to medaka fish embryo development of okadaic acid and crude extracts of Prorocentrum dinoflagellates.	Toxicon : official journal of the International Society on Toxinology 20070615
Adenosine protects against suicidal erythrocyte death.	Pflugers Archiv : European journal of physiology 20070601
Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.	American journal of physiology. Gastrointestinal and liver physiology 20070601
Clarification of the C-35 stereochemistries of dinophysistoxin-1 and dinophysistoxin-2 and its consequences for binding to protein phosphatase.	Chemical research in toxicology 20070601
Downregulation of the reduced folate carrier transport activity by phenobarbital-type cytochrome P450 inducers and protein kinase C activators.	Biochimica et biophysica acta 20070601
Inhibitory effect of polyunsaturated fatty acids on apoptosis induced by etoposide, okadaic acid and AraC in Neuro2a cells.	Acta medica Okayama 20070601
Hybrid lethality in interspecific F1 hybrid Nicotiana gossei x N. tabacum involves a MAP-kinases signalling cascade.	Plant biology (Stuttgart, Germany) 20070501
Okadaic acid and trifluoperazine enhance Agrobacterium-mediated transformation in eastern white pine.	Plant cell reports 20070501
Activation of PKCdelta and p38delta MAPK during okadaic acid dependent keratinocyte apoptosis.	Archives of dermatological research 20070501
Coordinate regulation of phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase by light and CO2 during C4 photosynthesis.	Plant physiology 20070501
Expression of protein phosphatase 2A mutants and silencing of the regulatory B alpha subunit induce a selective loss of acetylated and detyrosinated microtubules.	Journal of neurochemistry 20070501
Sp1-mediated transcription is involved in the induction of leptin by insulin-stimulated glucose metabolism.	Journal of molecular endocrinology 20070501
Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells.	Journal of cellular biochemistry 20070415
Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIalpha is regulated directly by protein phosphatase 2A.	The Biochemical journal 20070415
Effects of tau phosphorylation on proteasome activity.	FEBS letters 20070403
Proper chromatin condensation and maintenance of histone H3 phosphorylation during mouse oocyte meiosis requires protein phosphatase activity.	Biology of reproduction 20070401
Feasibility of gamma irradiation as a stabilisation technique in the preparation of tissue reference materials for a range of shellfish toxins.	Analytical and bioanalytical chemistry 20070401
In vitro toxicity of tetrabromobisphenol-A on cerebellar granule cells: cell death, free radical formation, calcium influx and extracellular glutamate.	Toxicological sciences : an official journal of the Society of Toxicology 20070401
Freeze-drying for the stabilisation of shellfish toxins in mussel tissue (Mytilus edulis) reference materials.	Analytical and bioanalytical chemistry 20070401
Methylation of the C-terminal leucine residue of the PP2A catalytic subunit is unnecessary for the catalytic activity and the binding of regulatory subunit (PR55/B).	Biochemical and biophysical research communications 20070323
Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge.	Cell 20070309
Evaluation of the effects of the marine toxin okadaic acid by using FETAX assay.	Toxicology letters 20070308
Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion.	Neuroscience 20070302
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.	The Journal of physiology 20070301
Down-regulation of ERK but not MEK phosphorylation in cultured endothelial cells by repeated changes in cyclic stretch.	Cardiovascular research 20070301
N-CoR pathway targeting induces glioblastoma derived cancer stem cell differentiation.	Cell cycle (Georgetown, Tex.) 20070215
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA.	The Journal of biological chemistry 20070209
A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.	Current biology : CB 20070206
Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor.	American journal of physiology. Heart and circulatory physiology 20070201
Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling.	American journal of physiology. Lung cellular and molecular physiology 20070201
Direct modulation of Ca(2+)-activated K(+) current by H-89 in rabbit coronary arterial smooth muscle cells.	Vascular pharmacology 20070201
Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation.	Prostaglandins & other lipid mediators 20070201
Regulatory role of kinases and phosphatases on the internalisation of caveolae in HepG2 cells.	Micron (Oxford, England : 1993) 20070101
Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.	Cellular signalling 20070101
Role of protein phosphatase 2A in calcium-dependent chloride secretion by human colonic epithelial cells.	American journal of physiology. Cell physiology 20070101
Relative toxicity of dinophysistoxin-2 (DTX-2) compared with okadaic acid, based on acute intraperitoneal toxicity in mice.	Toxicon : official journal of the International Society on Toxinology 20070101
Small-molecule inhibitors of ser/thr protein phosphatases: specificity, use and common forms of abuse.	Methods in molecular biology (Clifton, N.J.) 20070101
Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated.	Methods in molecular biology (Clifton, N.J.) 20070101
Augmenting effect of serotonin on the voltage-dependent Ca2+ current and subsequently activated K+ current in Aplysia neurons.	The Tohoku journal of experimental medicine 20070101
Cold stress defense in the freshwater sponge Lubomirskia baicalensis. Role of okadaic acid produced by symbiotic dinoflagellates.	The FEBS journal 20070101
The antinociceptive effect of morphine is reversed by okadaic acid in morphine-naive but not in morphine-tolerant mice.	Pharmacology, biochemistry, and behavior 20070101
Analysis of mitotic phosphorylation of borealin.	BMC cell biology 20070101
Signalling pathways involved in the control of sperm cell volume.	Reproduction (Cambridge, England) 20070101
Effect of enucleation on inactivation of cytostatic factor activity in matured rat oocytes.	Cloning and stem cells 20070101
Okadaic acid (1 microM) accelerates S phase and mitosis but inhibits heterochromatin replication and metaphase anaphase transition in Vicia faba meristem cells.	Journal of experimental botany 20070101
[Phycotoxins of ASP, PSP and DSP groups in aquaris organisms].	Voprosy pitaniia 20070101
Lactoferrin stimulates erythrocyte Na+/K+ -adenosine triphosphatase: effect of some modulators of membrane phosphorylation.	Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress.	The Biochemical journal 20061215
Cytoskeletal scaffolds regulate riboflavin endocytosis and recycling in placental trophoblasts.	The Journal of nutritional biochemistry 20061201
Okadaic acid induces phosphorylation of p65NF-kappaB on serine 536 and activates NF-kappaB transcriptional activity in human osteoblastic MG63 cells.	Journal of cellular biochemistry 20061201
Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes.	Molecular and cellular biochemistry 20061201
Non-muscle myosin-II-B filament regulation of paracellular resistance in cervical epithelial cells is associated with modulation of the cortical acto-myosin.	Journal of the Society for Gynecologic Investigation 20061201
Purification and characterization of protein phosphatase 2A from petals of the tulip Tulipa gesnerina.	Journal of biochemistry and molecular biology 20061130
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.	Neuron 20061109
Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes.	American journal of physiology. Cell physiology 20061101
Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia.	Neurochemistry international 20061101
Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei.	Experimental cell research 20061101
Lymph node cells from BALB/c mice with chronic visceral leishmaniasis exhibiting cellular anergy and apoptosis: involvement of Ser/Thr phosphatase.	Apoptosis : an international journal on programmed cell death 20061101
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.	The Journal of biological chemistry 20061020
Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins.	Cell 20061020
Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A.	Oncogene 20061019
The alpha4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A.	The Journal of biological chemistry 20061013
Okadaic acid induced cyclin B1 expression and mitotic catastrophe in rat cortex.	Neuroscience letters 20061009
Detailed profiles of 7-O-acyl esters in plankton and shellfish from the Portuguese coast.	Journal of chromatography. A 20060922
siRNA-mediated depletion of endogenous protein phosphatase 2Acalpha markedly attenuates ceramide-activated protein phosphatase activity in insulin-secreting INS-832/13 cells.	Biochemical and biophysical research communications 20060922
Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells.	Journal of cellular biochemistry 20060901
Protective effect of carvedilol on oxidative stress induced by okadaic acid in N1E-115 cells.	Pharmacological research 20060901
Desensitization of GSTF8 induction by a prior chemical treatment is long lasting and operates in a tissue-dependent manner.	Plant physiology 20060901
Activation of sodium transport in rat erythrocytes by inhibition of protein phosphatases 1 and 2A.	Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060901
Regulation of cytosolic PlA2 activity by PP1/PP2A serine/threonine phosphatases in human platelets.	Platelets 20060901
Deletion of synapsins I and II genes alters the size of vesicular pools and rabphilin phosphorylation.	Brain research 20060830
Rb2/p130 and protein phosphatase 2A: key mediators of ovarian carcinoma cell growth suppression by all-trans retinoic acid.	Oncogene 20060828
Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics.	The Biochemical journal 20060815

A mollusk VDR/PXR/CAR-like (NR1J) nuclear receptor provides insight into ancient detoxification mechanisms.

Aquatic toxicology (Amsterdam, Netherlands) 20160501

Hydroxyflutamide affects connexin 43 via the activation of PI3K/Akt-dependent pathway but has no effect on the crosstalk between PI3K/Akt and ERK1/2 pathways at the Raf-1 kinase level in primary rat Sertoli cells.

Toxicology in vitro : an international journal published in association with BIBRA 20160301

Dopamine D2 receptors' effects on renal inflammation are mediated by regulation of PP2A function.

American journal of physiology. Renal physiology 20160115

Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons.

PloS one 20160101

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Archives of toxicology 20151201

Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150901

Microvascular dysfunction with increased vascular leakage response in mice systemically exposed to arsenic.

Cardiovascular toxicology 20140901

PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a.

Chemico-biological interactions 20140805

CYP3A4 activity reduces the cytotoxic effects of okadaic acid in HepaRG cells.

Archives of toxicology 20140801

Active elimination of the marine biotoxin okadaic acid by P-glycoprotein through an in vitro gastrointestinal barrier.

Toxicology letters 20140303

Modulation of albumin-induced endoplasmic reticulum stress in renal proximal tubule cells by upregulation of mapk phosphatase-1.

Chemico-biological interactions 20131025

Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.

Toxicology and applied pharmacology 20131001

The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in T-cells from controls and systemic lupus erythematosus patients.

The Journal of biological chemistry 20130726

The marine toxin okadaic acid induces alterations in the expression level of cancer-related genes in human neuronal cells.

Ecotoxicology and environmental safety 20130601

Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human.

Blood 20130418

Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20130401

Comparative toxicological study of the novel protein phosphatase inhibitor 19-Epi-okadaic acid in primary cultures of rat cerebellar cells.

Toxicological sciences : an official journal of the Society of Toxicology 20130401

RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase Iα.

Cellular signalling 20130301

Study of cytoskeletal changes induced by okadaic acid in HL-7702 liver cells and development of a fluorimetric microplate assay for detecting diarrhetic shellfish poisoning.

Environmental toxicology 20130201

Algal toxins and reverse osmosis desalination operations: laboratory bench testing and field monitoring of domoic acid, saxitoxin, brevetoxin and okadaic acid.

Water research 20121201

Sucrose synthase activity and carbohydrates content in relation to phosphorylation status of Vicia faba root meristems during reactivation from sugar depletion.

Journal of plant physiology 20121101

Cytotoxicity of yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.

Toxicon : official journal of the International Society on Toxinology 20121101

Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route.

Toxicon : official journal of the International Society on Toxinology 20121001

Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid-induced neurodegeneration model.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20121001

MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding.

The New phytologist 20121001

Effects of okadaic acid on haemocytes from Mytilus galloprovincialis: a comparison between field and laboratory studies.

Marine environmental research 20121001

Annexin A9 is a periplakin interacting partner in membrane-targeted cytoskeletal linker protein complexes.

FEBS letters 20120921

Automated flow-through amperometric immunosensor for highly sensitive and on-line detection of okadaic acid in mussel sample.

Talanta 20120915

Okadaic acid induced neurotoxicity leads to central cholinergic dysfunction in rats.

European journal of pharmacology 20120905

Toxins in mussels (Mytilus galloprovincialis) associated with diarrhetic shellfish poisoning episodes in China.

Toxicon : official journal of the International Society on Toxinology 20120901

Isolation and characterization of an enzyme from the Greenshell™ mussel Perna canaliculus that hydrolyses pectenotoxins and esters of okadaic acid.

Toxicon : official journal of the International Society on Toxinology 20120901

Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.

Journal of lipid research 20120901

Elucidation of the mass fragmentation pathways of the polyether marine toxins, dinophysistoxins, and identification of isomer discrimination processes.

Rapid communications in mass spectrometry : RCM 20120830

Occurrence of diarrhetic shellfish poisoning (DSP) toxins in clams (Ruditapes decussatus) from Tunis north lagoon.

Environmental monitoring and assessment 20120801

Cooling-increased phospho-β-arrestin-1 and β-arrestin-1 expression levels in 3T3-L1 adipocytes.

Cryobiology 20120801

Susceptibility of different mice strains to okadaic acid, a diarrhetic shellfish poisoning toxin.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120801

A protein phosphatase 2A catalytic subunit modulates blue light-induced chloroplast avoidance movements through regulating actin cytoskeleton in Arabidopsis.

Plant & cell physiology 20120801

Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.

Bioscience reports 20120801

Effects of ginkgolide A on okadaic acid-induced tau hyperphosphorylation and the PI3K-Akt signaling pathway in N2a cells.

Planta medica 20120801

Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells.

The Journal of biological chemistry 20120727

The structures of three metabolites of the algal hepatotoxin okadaic acid produced by oxidation with human cytochrome P450.

Bioorganic & medicinal chemistry 20120615

Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo.

International journal of molecular medicine 20120601

Highly sensitive detection of alkaline phosphatase using molecular beacon probes based on enzymatic polymerization.

Molecular and cellular probes 20120601

Auxin activates the plasma membrane H+-ATPase by phosphorylation during hypocotyl elongation in Arabidopsis.

Plant physiology 20120601

A study on neuroinflammatory marker in brain areas of okadaic acid (ICV) induced memory impaired rats.

Life sciences 20120522

Increased phosphorylation of dynamin-related protein 1 and mitochondrial fission in okadaic acid-treated neurons.

Brain research 20120515

Okadaic acid-sensitive phosphatase is related to MII/G1 transition in mouse oocytes.

Zygote (Cambridge, England) 20120501

PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Single laboratory validation of a ready-to-use phosphatase inhibition assay for detection of okadaic acid toxins.

Toxins 20120501

Development of a novel label-free amperometric immunosensor for the detection of okadaic acid.

Analytica chimica acta 20120429

Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425

Quantitative proteomic analysis of okadaic acid treated mouse small intestines reveals differentially expressed proteins involved in diarrhetic shellfish poisoning.

Journal of proteomics 20120403

Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation.

Journal of biochemistry 20120401

Phosphorylation status of matrix metalloproteinase 2 in myocardial ischaemia-reperfusion injury.

Heart (British Cardiac Society) 20120401

Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data.

Journal of separation science 20120401

Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase.

The Journal of biological chemistry 20120323

A screening lateral flow immunochromatographic assay for on-site detection of okadaic acid in shellfish products.

Analytical biochemistry 20120315

Comparative study of toxicological and cell cycle effects of okadaic acid and dinophysistoxin-2 in primary rat hepatocytes.

Life sciences 20120310

Chromatin specialization in bivalve molluscs: a leap forward for the evaluation of Okadaic Acid genotoxicity in the marine environment.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.

European journal of immunology 20120301

Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.

Neurobiology of disease 20120301

Activation of MAP kinase family members triggered by TPA or ionomycin occurs via the protein phosphatase 4 pathway in Jurkat leukemia T cells.

Molecular medicine reports 20120301

[PP2A is involved in the inhibitory effect of progesterone on proliferation of mouse endometrial epithelial cells].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301

[Simultaneous determination of okadaic acid, dinophysistoxin, pectenotoxin and yessotoxin in shellfish by liquid chromatography-tandem mass spectrometry].

Se pu = Chinese journal of chromatography 20120301

Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222

Controlled release of drugs from gradient hydrogels for high-throughput analysis of cell-drug interactions.

Analytical chemistry 20120207

Activation of a tunicate (Ciona intestinalis) xenobiotic receptor orthologue by both natural toxins and synthetic toxicants.

Toxicon : official journal of the International Society on Toxinology 20120201

Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia.

Behavioural brain research 20120115

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.

Nature neuroscience 20120108

Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling.

British journal of pharmacology 20120101

The effect of okadaic acid on meiotic maturation of canine oocytes of different size.

Theriogenology 20120101

A simple colorimetric enzymatic-assay for okadaic acid detection based on the immobilization of protein phosphatase 2A in sol-gel.

Applied biochemistry and biotechnology 20120101

Okadaic acid inhibits cell growth and photosynthetic electron transport in the alga Dunaliella tertiolecta.

The Science of the total environment 20120101

Conjugation of genetically engineered protein phosphatases to magnetic particles for okadaic acid detection.

Journal of biotechnology 20120101

Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization.

BMC genomics 20120101

Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.

Marine drugs 20120101

Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137.

PloS one 20120101

[Effect of inhibitors serine/threonine protein kinases and protein phosphatases on mitosis progression of synchronized tobacco by-2 cells].

TSitologiia i genetika 20120101

Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure.

Journal of toxicology and environmental health. Part A 20120101

Okadaic acid and dinophysis toxin 2 have differential toxicological effects in hepatic cell lines inducing cell cycle arrest, at G0/G1 or G2/M with aberrant mitosis depending on the cell line.

Archives of toxicology 20111201

Mitochondrial dysfunction: a crucial event in okadaic acid (ICV) induced memory impairment and apoptotic cell death in rat brain.

Pharmacology, biochemistry, and behavior 20111201

Microcystin congener- and concentration-dependent induction of murine neuron apoptosis and neurite degeneration.

Toxicological sciences : an official journal of the Society of Toxicology 20111201

Okadaic acid induces apoptosis through the PKR, NF-κB and caspase pathway in human osteoblastic osteosarcoma MG63 cells.

Toxicology in vitro : an international journal published in association with BIBRA 20111201

Two ancient bacterial-like PPP family phosphatases from Arabidopsis are highly conserved plant proteins that possess unique properties.

Plant physiology 20111201

Okadaic acid and microcystin insensitive PPP-family phosphatases may represent novel biotechnology targets.

Plant signaling & behavior 20111201

Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.

Toxicology letters 20111130

Food poisoning outbreaks linked to mussels contaminated with okadaic acid and ester dinophysistoxin-3 in France, June 2009.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20111117

Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt.

Oncogene 20111103

K252a-sensitive protein kinases but not okadaic acid-sensitive protein phosphatases regulate methyl jasmonate-induced cytosolic Ca2+ oscillation in guard cells of Arabidopsis thaliana.

Journal of plant physiology 20111101

The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons.

Journal of neuroscience research 20111101

Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-terminal kinase pathway.

European journal of cancer (Oxford, England : 1990) 20111101

Protective effects of ginsenoside Rd against okadaic acid-induced neurotoxicity in vivo and in vitro.

Journal of ethnopharmacology 20111031

Hydroxytyrosol induces vascular smooth muscle cells apoptosis through NO production and PP2A activation with subsequent inactivation of Akt.

Planta medica 20111001

Integration of a pump and an electrical sensor into a membrane-based PDMS microbioreactor for cell culture and drug testing.

Biomedical microdevices 20111001

Development of an efficient protein phosphatase-based colorimetric test for okadaic acid detection.

Analytica chimica acta 20110930

Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling.

The Journal of biological chemistry 20110923

Co-pathological connected primary neurons in a microfluidic device for Alzheimer studies.

Biotechnology and bioengineering 20110901

Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.

Bone 20110901

Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation.

Toxicological sciences : an official journal of the Society of Toxicology 20110901

Adrenergic regulation of the distribution of transducer of regulated cAMP-response element-binding protein (TORC2) in rat pinealocytes.

Endocrinology 20110901

Sp1 is a transcription repressor to stanniocalcin-1 expression in TSA-treated human colon cancer cells, HT29.

Journal of cellular biochemistry 20110801

Effect of uncontrolled factors in a validated liquid chromatography-tandem mass spectrometry method question its use as a reference method for marine toxins: major causes for concern.

Analytical chemistry 20110801

Production of monoclonal antibody and application in indirect competitive ELISA for detecting okadaic acid and dinophytoxin-1 in seafood.

Environmental science and pollution research international 20110801

An electrochemical immunosensor based on covalent immobilization of okadaic acid onto screen printed carbon electrode via diazotization-coupling reaction.

Talanta 20110715

N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.

European journal of medicinal chemistry 20110601

First report on the detection of pectenotoxin groups in Chinese shellfish by LC-MS/MS.

Toxicon : official journal of the International Society on Toxinology 20110601

Okadaic acid induces morphological changes, apoptosis and cell cycle alterations in different human cell types.

Journal of environmental monitoring : JEM 20110601

[Influence of PP2A activator on proliferation of HL-60 cells and analysis of PP2A activity changes in patients with acute myeloid leukemia].

Zhongguo shi yan xue ye xue za zhi 20110601

PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway.

Cancer letters 20110528

Neurobiological aspects of Alzheimer's disease.

Expert opinion on therapeutic targets 20110501

Induction of oxidative DNA damage by the marine toxin okadaic acid depends on human cell type.

Toxicon : official journal of the International Society on Toxinology 20110501

Protein phosphatase 2A B55 and A regulatory subunits interact with nitrate reductase and are essential for nitrate reductase activation.

Plant physiology 20110501

Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.

The Journal of biological chemistry 20110422

Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation.

The Journal of biological chemistry 20110415

LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.

The Journal of biological chemistry 20110408

Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401

Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.

Journal of cellular biochemistry 20110401

Esterification of okadaic acid in the mussel Mytilus galloprovincialis.

Toxicon : official journal of the International Society on Toxinology 20110401

Enzyme-linked immunosensor based on super paramagnetic nanobeads for easy and rapid detection of okadaic acid.

Analytica chimica acta 20110401

The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.

The Journal of biological chemistry 20110225

Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.

Apoptosis : an international journal on programmed cell death 20110201

Microencapsulation of okadaic acid as a tool for studying the accumulation of DSP toxins in mussels.

Marine environmental research 20110201

Analysis of the passage of the marine biotoxin okadaic acid through an in vitro human gut barrier.

Toxicology 20110111

Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells.

Cellular signalling 20110101

Results of a European interlaboratory method validation study for the quantitative determination of lipophilic marine biotoxins in raw and cooked shellfish based on high-performance liquid chromatography-tandem mass spectrometry. Part I: collaborative study.

Analytical and bioanalytical chemistry 20110101

Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development.

Anti-cancer agents in medicinal chemistry 20110101

Characterization of apoptotic changes induced by yessotoxin in the Bel7402 human hepatoma cell line.

Molecular medicine reports 20110101

BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

PloS one 20110101

LC-MS/MS analysis of diarrhetic shellfish poisoning (DSP) toxins, okadaic acid and dinophysistoxin analogues, and other lipophilic toxins.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101

Evaluation of genotoxicity in gills and hemolymph of clam Ruditapes decussatus fed with the toxic dinoflagellate Prorocentrum lima.

Journal of toxicology and environmental health. Part A 20110101

Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and γH2AX analysis.

Journal of toxicology and environmental health. Part A 20110101

[Reconstruction of spatial structure of plant protein phosphatase type-1 and -2A in complex with okadaic acid].

TSitologiia i genetika 20110101

Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B.

PloS one 20110101

Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.

PloS one 20110101

Enzyme-linked immunosorbent assay for okadaic acid: investigation of analytical conditions and sample matrix on assay performance.

Journal of AOAC International 20110101

Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma.

PloS one 20110101

Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.

The Journal of biological chemistry 20101224

Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation.

Cellular signalling 20101201

Strategies for the elimination of matrix effects in the liquid chromatography tandem mass spectrometry analysis of the lipophilic toxins okadaic acid and azaspiracid-1 in molluscan shellfish.

Journal of chromatography. A 20101105

An okadaic acid-induced model of tauopathy and cognitive deficiency.

Brain research 20101104

Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids.

Functional & integrative genomics 20101101

Binding of diarrheic shellfish poisoning toxins to okadaic acid binding proteins purified from the sponge Halichondria okadai.

Bioorganic & medicinal chemistry 20101101

Mediterranean mussel gene expression profile induced by okadaic acid exposure.

Environmental science & technology 20101101

Protein phosphatase 1γ is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage.

EMBO reports 20101101

Lily Cdc42/Rac-interactive binding motif-containing protein, a Rop target, involves calcium influx and phosphoproteins during pollen germination and tube growth.

Plant signaling & behavior 20101101

Formal total synthesis of okadaic acid via regiocontrolled gold(I)-catalyzed spiroketalizations.

Organic letters 20101015

Corozalic acid: a key okadaic acid biosynthetic precursor with phosphatase inhibition activity.

Chemistry (Weinheim an der Bergstrasse, Germany) 20101011

Differential contribution of the MTOR and MNK pathways to the regulation of mRNA translation in meiotic and postmeiotic mouse male germ cells.

Biology of reproduction 20101001

A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.

Biochimica et biophysica acta 20101001

Decreased activity of the Na+/H+ exchanger by phosphodiesterase 5A inhibition is attributed to an increase in protein phosphatase activity.

Hypertension (Dallas, Tex. : 1979) 20101001

[Effects of gensenoside Rg1 on tau protein phosphorylation induced by okadaic acid in rat brain slices].

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20101001

Naturally contaminated shellfish samples: quantification of diarrhetic shellfish poisoning toxins in unhydrolysed and hydrolysed extracts and cytotoxicity assessment.

Journal of applied toxicology : JAT 20101001

Activation of eukaryotic initiation factor-2 α-kinases in okadaic acid-treated neurons.

Neuroscience 20100915

Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1.

Neurochemistry international 20100901

The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau.

Journal of neurochemistry 20100901

Phosphorylation of the CREB-specific coactivator TORC2 at Ser(307) regulates its intracellular localization in COS-7 cells and in the mouse liver.

American journal of physiology. Endocrinology and metabolism 20100901

Effect of PP-2A on neurite outgrowth in neuronal cells.

In vitro cellular & developmental biology. Animal 20100901

Dinoflagellate polyether within the yessotoxin, pectenotoxin and okadaic acid toxin groups: characterization, analysis and human health implications.

Toxicon : official journal of the International Society on Toxinology 20100815

Intra-amygdalar okadaic acid enhances conditioned taste aversion learning and CREB phosphorylation in rats.

Brain research 20100812

Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons.

Journal of neurochemistry 20100801

Visualization of the interaction between Gbetagamma and tubulin during light-induced cell elongation of Blepharisma japonicum.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100801

Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner.

Brain research 20100723

Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.

Journal of medicinal chemistry 20100722

Assessment of okadaic acid effects on cytotoxicity, DNA damage and DNA repair in human cells.

Mutation research 20100707

Kinases and phosphatases in ischaemic preconditioning: a re-evaluation.

Basic research in cardiology 20100701

Regulation of postsynaptic gephyrin cluster size by protein phosphatase 1.

Molecular and cellular neurosciences 20100701

PhosphoMARCKS drives motility of mouse melanoma cells.

Cellular signalling 20100701

Biodosimetry for high dose accidental exposures by drug induced premature chromosome condensation (PCC) assay.

Mutation research 20100617

Effects of toxic and non-toxic blue mussel meal on health and product quality of laying hens.

Journal of animal physiology and animal nutrition 20100601

First U.S. report of shellfish harvesting closures due to confirmed okadaic acid in Texas Gulf coast oysters.

Toxicon : official journal of the International Society on Toxinology 20100601

A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.

Molecular endocrinology (Baltimore, Md.) 20100601

Development of ELISAs for detecting domoic acid, okadaic acid, and saxitoxin and their applicability for the detection of marine toxins in samples collected in Belgium.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601

Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.

Molecular cancer research : MCR 20100601

First evidence of Okadaic acid acyl-derivative and Dinophysistoxin-3 in mussel samples collected in Chiloe Island, Southern Chile.

The Journal of toxicological sciences 20100601

Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity.

Hematology (Amsterdam, Netherlands) 20100601

Ser123 is essential for the water channel activity of McPIP2;1 from Mesembryanthemum crystallinum.

The Journal of biological chemistry 20100528

Acute regulation of renal Na+/H+ exchanger NHE3 by dopamine: role of protein phosphatase 2A.

American journal of physiology. Renal physiology 20100501

Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal.

Stem cells (Dayton, Ohio) 20100501

[Protective effects of IGF-1 on cell injuries and tau hyperphosphorylation induced by okadaic acid].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100501

Comparative study of various immune parameters in three bivalve species during a natural bloom of Dinophysis acuminata in Santa Catarina Island, Brazil.

Toxins 20100501

Maintained activity of glycogen synthase kinase-3beta despite of its phosphorylation at serine-9 in okadaic acid-induced neurodegenerative model.

Biochemical and biophysical research communications 20100430

Determination of okadaic acid, dinophysistoxin-1 and related esters in Greek mussels using HPLC with fluorometric detection, LC-MS/MS and mouse bioassay.

Toxicon : official journal of the International Society on Toxinology 20100401

Okadaic acid induces apoptosis in Down syndrome fibroblasts.

Toxicology in vitro : an international journal published in association with BIBRA 20100401

Embryotoxic effects of the marine biotoxin okadaic acid on murine embryonic stem cells.

Toxicon : official journal of the International Society on Toxinology 20100401

cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes.

Journal of molecular and cellular cardiology 20100401

Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.

Proteomics 20100401

Encystation process of Giardia lamblia: morphological and regulatory aspects.

Archives of microbiology 20100401

Inhibition of Ser/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors.

The Journal of biological chemistry 20100312

Comparison of gene expression profiles in BALB/c 3T3 transformed foci exposed to tumor promoting agents.

Toxicology in vitro : an international journal published in association with BIBRA 20100301

NG108-15 cell-based and protein phosphatase inhibition assays as alternative semiquantitative tools for the screening of lipophilic toxins in mussels. Okadaic acid detection.

Toxicology in vitro : an international journal published in association with BIBRA 20100301

Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

Dynamic regulation of guard cell anion channels by cytosolic free Ca2+ concentration and protein phosphorylation.

The Plant journal : for cell and molecular biology 20100301

NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.

American journal of physiology. Renal physiology 20100301

High-sensitive flow-based kinetic exclusion assay for okadaic acid assessment in shellfish samples.

Biosensors & bioelectronics 20100215

Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors.

The Journal of biological chemistry 20100212

Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues.

Apoptosis : an international journal on programmed cell death 20100201

Requirement for proteolysis in spindle assembly checkpoint silencing.

Cell cycle (Georgetown, Tex.) 20100201

Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity.

Brain research 20100114

CLA reduces breast cancer cell growth and invasion through ERalpha and PI3K/Akt pathways.

Chemico-biological interactions 20100105

Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia.