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77737-08-7

77737-08-7 | SODIUM 5-OXO-4,4-DIPHENYL-1H-IMIDAZOL-2-OLATE

CAS No: 77737-08-7 Catalog No: AG005G1U MDL No:

Product Description

Catalog Number:
AG005G1U
Chemical Name:
SODIUM 5-OXO-4,4-DIPHENYL-1H-IMIDAZOL-2-OLATE
CAS Number:
77737-08-7
Molecular Formula:
C15H11N2NaO2
Molecular Weight:
274.2498
IUPAC Name:
sodium;5-oxo-4,4-diphenyl-1H-imidazol-2-olate
InChI:
InChI=1S/C15H12N2O2.Na/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12;/h1-10H,(H2,16,17,18,19);/q;+1/p-1
InChI Key:
FJPYVLNWWICYDW-UHFFFAOYSA-M
SMILES:
O=C1NC(=NC1(c1ccccc1)c1ccccc1)[O-].[Na+]
EC Number:
211-148-2

Properties

Complexity:
367  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
274.072g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
274.255g/mol
Monoisotopic Mass:
274.072g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
64.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

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One-way multiplexed immunoassay strategy for simultaneous determination of multi-analytes by microchip electrophoresis. The Analyst 20110521
Reduced phenytoin levels in an epileptic patient following Roux-En-Y gastric bypass for obesity. Obesity surgery 20110501
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Effects of phenytoin and Echinacea purpurea extract on proliferation and apoptosis of mouse embryonic palatal mesenchymal cells. Journal of cellular biochemistry 20110501
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. European journal of clinical pharmacology 20110501
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Sturge Weber syndrome. The Journal of the Association of Physicians of India 20110501
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Influence of water/alkoxide ratio in the synthesis of nanosized sol-gel titania on the release of phenytoin. Langmuir : the ACS journal of surfaces and colloids 20110405
Video recording devices as a diagnostic aid. The Journal of emergency medicine 20110401
Can topical phenytoin augment the therapeutic efficacy of PUVA against vitiligo? A double-blind, randomized, bilateral-comparison, placebo-controlled study. The Journal of dermatological treatment 20110401
Idiopathic ventricular fibrillation controlled successfully with phenytoin. Journal of cardiovascular electrophysiology 20110401
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Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice. Pharmacology, biochemistry, and behavior 20110401
Embryoprotective role of endogenous catalase in acatalasemic and human catalase-expressing mouse embryos exposed in culture to developmental and phenytoin-enhanced oxidative stress. Toxicological sciences : an official journal of the Society of Toxicology 20110401
Effects of intraperitoneal administration of the phenytoin on the skeletal system of rat fetus. Seizure 20110401
Trimethoprim/sulfamethoxazole-induced phenytoin toxicity in the elderly: a population-based study. British journal of clinical pharmacology 20110401
Early postnatal exposure of rats to lamotrigine, but not phenytoin, reduces seizure threshold in adulthood. Epilepsia 20110401
ECG myogenic artifacts during clonic seizures: a disturbing (and interesting) finding. Journal of clinical monitoring and computing 20110401
Pharmacogenetics: reality or fiction? Or are we there yet? Arquivos de neuro-psiquiatria 20110401
CYP2C9 polymorphism in patients with epilepsy: genotypic frequency analyzes and phenytoin adverse reactions correlation. Arquivos de neuro-psiquiatria 20110401
Drug-induced gingival overgrowth. Disease-a-month : DM 20110401
Non-immunosuppressive treatment for IgA nephropathy. The Cochrane database of systematic reviews 20110316
A rapid and efficient ultrasound-assisted synthesis of 5,5-diphenylhydantoins and 5,5-diphenyl-2-thiohydantoins. Ultrasonics sonochemistry 20110301
Bisphosphonates in phenytoin-induced bone disorder. Bone 20110301
The DRESS syndrome: the great clinical mimicker. Pharmacotherapy 20110301
Universal wet-milling technique to prepare oral nanosuspension focused on discovery and preclinical animal studies - Development of particle design method. International journal of pharmaceutics 20110227
Seizures in pregnancy/eclampsia. Emergency medicine clinics of North America 20110201
Status epilepticus. Indian journal of pediatrics 20110201
HLA-B*1502 genotyping in two Chinese patients with phenytoin-induced Stevens-Johnson syndrome. Epilepsy & behavior : E&B 20110201
Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin. Bioorganic & medicinal chemistry 20110201
Excretion of the principal urinary metabolites of phenytoin and absolute oral bioavailability determined by use of a stable isotope in patients with epilepsy. Therapeutic drug monitoring 20110201
Prophylactic anticonvulsants after subarachnoid hemorrhage. World neurosurgery 20110201
Comparison of short-duration levetiracetam with extended-course phenytoin for seizure prophylaxis after subarachnoid hemorrhage. World neurosurgery 20110201
A family with autosomal recessive generalised myotonia with Herculean appearance. The Journal of the Association of Physicians of India 20110201
An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges. Brain research 20110131
Anticonvulsant activity of embelin isolated from Embelia ribes. Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115
Refractory idiopathic ventricular tachycardia in a newborn treated successfully with phenytoin: old therapies are still effective in the current era. Pediatric cardiology 20110101
Dilantin therapy in an experimental model of traumatic brain injury: effects of limited versus daily treatment on neurological and behavioral recovery. Journal of neurotrauma 20110101
Occurrence and removal of pharmaceuticals and hormones through drinking water treatment. Water research 20110101
Question 2 Should phenytoin and carbamazepine be avoided in Asian populations with the HLA-B*1502 positive genetic variant? Archives of disease in childhood 20110101
Focal status epilepticus induced by hyperbaric oxygen therapy. The neurologist 20110101
Effect of particle size of parenteral suspensions on in vitro muscle damage. Pharmaceutical development and technology 20110101
Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy. The American journal of pathology 20110101
Voltage-gated potassium channel-complex antibody-associated limbic encephalitis. Psychosomatics 20110101
The use of topical phenytoin for healing of chronic venous ulcerations. International journal of surgery (London, England) 20110101
Phenytoin toxicity presenting as acute meningo-encephalitis in children. Neurology India 20110101
Refractory hiccups due to phenytoin therapy. Neurology India 20110101
Pure red cell aplasia with phenytoin following traumatic brain injury. Neurology India 20110101
[Resistance to vecuronium induced muscle relaxation in a patient with mental retardation receiving phenytoin for chronic anticonvulsant therapy]. Masui. The Japanese journal of anesthesiology 20110101
Effect of topical phenytoin on burn wound healing in rats. Indian journal of experimental biology 20110101
Co-encapsulation of a drug with a protein in erythrocytes for improved drug loading and release: phenytoin and bovine serum albumin (BSA). Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101
Pressure ulcers. BMJ clinical evidence 20110101
[Development of rapid genotyping methods for single nucleotide polymorphisms of cytochrome P450 2C9 (CYP2C9) and cytochrome P450 2C19 (CYP2C19) and their clinical application in pediatric patients with epilepsy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Adverse cognitive effects of phenytoin in severe brain injury: a case report. Brain injury 20110101
Epilepsy (partial). BMJ clinical evidence 20110101
Pharmacogenetics of the antiepileptic drugs phenytoin and lamotrigine. Drug metabolism and drug interactions 20110101
Case Study Interpretation--Houston: Case 1. Phenytoin-induced ‘‘pseudolymphoma’’. Cytometry. Part B, Clinical cytometry 20110101
Impact of seizure activity on free extracellular phenytoin concentrations in amygdala-kindled rats. Neuropharmacology 20110101
Phenytoin (Dilantin) and acupuncture therapy in the treatment of intractable oral and facial pain. Acupuncture & electro-therapeutics research 20110101
Phenytoin and phenytoin sodium. Report on carcinogens : carcinogen profiles 20110101
[Epilepsy in elderly]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
Identifying prognostic factors for drug rash with eosinophilia and systemic symptoms (DRESS). European journal of dermatology : EJD 20110101
Potential advantages of topical phenytoin as a novel anti psoriasis arsenal. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20110101
Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turkish neurosurgery 20110101
The effects of antiepileptic drugs on oral health. Journal (Canadian Dental Association) 20110101
Advisers recommend improved labeling for phenytoin, fosphenytoin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215
Targeted three-dimensional liquid chromatography: a versatile tool for quantitative trace analysis in complex matrices. Journal of chromatography. A 20101203
Seizure and coma following Kratom (Mitragynina speciosa Korth) exposure. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20101201
Seizures in patients with glioma treated with phenytoin and levetiracetam. Journal of neurosurgery 20101201
Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases. Archives of dermatology 20101201
Two percent topical phenytoin sodium solution in treating pyoderma gangrenosum: a cohort study. International wound journal 20101201
Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model. European journal of pharmacology 20101201
Consequences of telemedicine. Indian journal of pediatrics 20101201
Thermodynamics of drug nanoencapsulation: case study of phenytoin-poly (D, L-lactide) nanocarrier. Current drug delivery 20101201
Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer. Bioorganic & medicinal chemistry 20101201
Influence of CYP2C9 genetic polymorphism and undernourishment on plasma-free phenytoin concentrations in epileptic patients. Therapeutic drug monitoring 20101201
Hemi brain demyelination--a variant of acute disseminated encephalomyelitis. Indian journal of medical sciences 20101201
Retrograde ejaculation and abnormal hormonal profile in a subject under treatment with valproate and phenytoin. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20101201
Livedo racemosa, secondary to drug-induced systemic lupus erythematosus. Dermatology online journal 20101115
A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals 20101101
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study. Seizure 20101101
Refractory nonconvulsive status epilepticus responsive to music as an add-on therapy: a second case. Epilepsy & behavior : E&B 20101101
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population. Seizure 20101101
[Establishment of embryonic stem cell for evaluation of development neurotoxicity and test the validation of embryonic stem cell]. Wei sheng yan jiu = Journal of hygiene research 20101101
Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin. Bioorganic & medicinal chemistry letters 20101015
Magnesium sulphate versus phenytoin for eclampsia. The Cochrane database of systematic reviews 20101006
Genotoxic evaluation of antiepileptic drugs by Drosophila somatic mutation and recombination test. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial. Epilepsia 20101001
Age and comedications influence levetiracetam pharmacokinetics in children. Pediatric neurology 20101001
Acute generalized exanthematous pustulosis as a manifestation of anticonvulsant hypersensitivity syndrome. The Annals of pharmacotherapy 20101001
Management of neonatal seizures. Indian journal of pediatrics 20101001
Should phenytoin or barbiturates be used as second-line anticonvulsant therapy for toxicological seizures? Clinical toxicology (Philadelphia, Pa.) 20101001
Phenytoin induced status epilepticus. Neurosciences (Riyadh, Saudi Arabia) 20101001
The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. Birth defects research. Part B, Developmental and reproductive toxicology 20101001
Contemporary pharmacologic issues in the management of traumatic brain injury. Journal of pharmacy practice 20101001
Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin. Epilepsia 20100901
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. Biochimie 20100901
Effect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport. Molecular genetics and metabolism 20100901
Phenytoin-induced visual disturbances mimicking Delirium Tremens in a child. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100901
Genes, environment, and orofacial clefting: N-acetyltransferase and folic acid. The Journal of craniofacial surgery 20100901
Synthesis and anticonvulsant activity of 7-alkoxy-triazolo-[3, 4-b]benzo[d]thiazoles. Medicinal chemistry (Shariqah (United Arab Emirates)) 20100901
Adverse effect of phenytoin on glucocorticoid replacement in a child with adrenal insufficiency. Journal of pediatric endocrinology & metabolism : JPEM 20100901
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Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9. European journal of clinical pharmacology 20100801
Hypoxia and the Edema Syndrome: elucidation of a mechanism of teratogenesis. Birth defects research. Part B, Developmental and reproductive toxicology 20100801
Drug refractoriness of epileptiform activity in organotypic hippocampal slice cultures depends on the mode of provocation. Epilepsy research 20100801
Effects of phenytoin on Satb2 and Hoxa2 gene expressions in mouse embryonic craniofacial tissue. Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801
Phenytoin in toxin-induced seizures. Emergency medicine Australasia : EMA 20100801
Empact syndrome: a case report and review of the literature. International journal of dermatology 20100801
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients. European journal of clinical pharmacology 20100701
5,5-Diphenyl-2-thiohydantoin-N10 (DPTH-N10) suppresses proliferation of cultured colon cancer cell line COLO-205 by inhibiting DNA synthesis and activating apoptosis. Naunyn-Schmiedeberg's archives of pharmacology 20100701
Epithelial to mesenchymal transition in gingival overgrowth. The American journal of pathology 20100701
Successful hemodialysis in a phenytoin overdose: case report and review of the literature. Clinical nephrology 20100701
Occipital lobe seizures related to marked elevation of hemoglobin A1C: report of two cases. Seizure 20100701
Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment. Pharmacogenomics 20100701
The 'apparent clearance' of free phenytoin in elderly vs. younger adults. British journal of clinical pharmacology 20100701
Influence on Busilvex pharmacokinetics of clonazepam compared to previous phenytoin historical data. Anticancer research 20100701
Phenytoin induced vitamin D deficiency presenting as proximal muscle weakness. Indian pediatrics 20100701
Epilepsy (partial). BMJ clinical evidence 20100628
In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein. Life sciences 20100605
In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain. Toxicology in vitro : an international journal published in association with BIBRA 20100601
Trimetazidine exerts protection against increasing current electroshock seizure test in mice. Seizure 20100601
Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits. Birth defects research. Part C, Embryo today : reviews 20100601
Increasing the dose of voriconazole compensates for enzyme induction by phenytoin. British journal of clinical pharmacology 20100601
[Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities]. Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan 20100601
Phenytoin-associated hypersensitivity syndrome with features of DRESS and TEN/SJS. Cutis 20100601
The role of intravenous valproate in convulsive status epilepticus in the future. Acta neurologica Taiwanica 20100601
Construction and in vitro characterization of an optimized porosity-enabled amalgamated matrix for sustained transbuccal drug delivery. International journal of pharmaceutics 20100531
Omeprazole induces gastric permeability to digoxin. Digestive diseases and sciences 20100501
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100501
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients. Clinical neurology and neurosurgery 20100501
Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy. Clinical and experimental pharmacology & physiology 20100501
Determination of free and total levels of phenytoin in human plasma from patients with epilepsy by MEKC: an adequate alternative to HPLC. Electrophoresis 20100501
[Antiepileptic drugs in North America]. Brain and nerve = Shinkei kenkyu no shinpo 20100501
What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity? Clinical toxicology (Philadelphia, Pa.) 20100501
Acute generalized exanthematous pustulosis: analysis of cases managed in a tertiary hospital in Singapore. International journal of dermatology 20100501
Influence of etoricoxib on anticonvulsant activity of phenytoin and diazepam in experimental seizure models in mice. The Journal of pharmacy and pharmacology 20100501
Anticonvulsant activity of DNS II fraction in the acute seizure models. Journal of ethnopharmacology 20100421
Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis. Neurocritical care 20100401
Synthesis and evaluation of some new substituted benzothiazepine and benzoxazepine derivatives as anticonvulsant agents. European journal of medicinal chemistry 20100401
Phenytoin blood concentrations in hospitalized geriatric patients: oral versus nasogastric feeding tube administration. Therapeutic drug monitoring 20100401
Phenytoin-induced acute generalized exanthemous pustulosis. Journal of the American Academy of Dermatology 20100401
Neuroanesthesiology update. Journal of neurosurgical anesthesiology 20100401
Feasibility of microdialysis to determine interstitial rocuronium concentration in the muscle tissue of anesthetized neurosurgical patients. Journal of neurosurgical anesthesiology 20100401
Intracerebral hemorrhage and seizures. Journal of neurosurgery 20100401
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy. Archives of neurology 20100401
Review article: phenytoin use and efficacy in the ED. Emergency medicine Australasia : EMA 20100401
Phenytoin induced status epilepticus. Neurosciences (Riyadh, Saudi Arabia) 20100401
Possible acute thrombocytopenia post esomeprazole and hydantoin coadministration. Journal of pharmacy practice 20100401
Anticonvulsant activity of Benkara malabarica (Linn.) root extract: In vitro and in vivo investigation. Journal of ethnopharmacology 20100324
Lorazepam versus diazepam-phenytoin combination in the treatment of convulsive status epilepticus in children: a randomized controlled trial. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100301
Purple glove syndrome: a case report. Hand surgeons and physicians be aware. Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20100301
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats. Epilepsia 20100301
7-Benzyloxyresorufin-O-dealkylase activity as a marker for measuring cytochrome P450 CYP3A induction in mouse liver. Analytical biochemistry 20100301
Inspiratory stridor secondary to palatolingual myokymia in a Maltese dog. The Journal of small animal practice 20100301
Persistent focal seizures after cat scratch encephalopathy. Pediatric neurology 20100301
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. Pharmacogenomics 20100301
Effect of prolonged phenytoin administration on rat brain gene expression assessed by DNA microarrays. Experimental biology and medicine (Maywood, N.J.) 20100301
From the clinics to the bench and back - phenytoin as a mood stabilizer? Experimental biology and medicine (Maywood, N.J.) 20100301
Serious generalized tonic-clonic seizures induced by aripiprazole. Progress in neuro-psychopharmacology & biological psychiatry 20100201
COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. Neuropharmacology 20100201
CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. The Journal of pharmacology and experimental therapeutics 20100201
Selection between Michaelis-Menten and target-mediated drug disposition pharmacokinetic models. Journal of pharmacokinetics and pharmacodynamics 20100201
Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation. Epilepsy & behavior : E&B 20100201
Vagal nerve stimulator use during pregnancy for treatment of refractory seizure disorder. Obstetrics and gynecology 20100201
Update on pressure ulcer management and deep tissue injury. The Annals of pharmacotherapy 20100201
Novel spray freeze-drying technique using four-fluid nozzle-development of organic solvent system to expand its application to poorly water soluble drugs. Chemical & pharmaceutical bulletin 20100201
Unexpected postoperative seizure after mastoid surgery--a case report. Middle East journal of anaesthesiology 20100201
Similar effects of lamotrigine and phenytoin against cortical epileptic foci in immature rats. Physiological research 20100101
Stevens-Johnson syndrome following concurrent phenytoin and holocranial radiotherapy. Acta oncologica (Stockholm, Sweden) 20100101
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations. Pharmacogenetics and genomics 20100101
Effect of an educational initiative on physicians' use of weight-based fosphenytoin loading doses in the emergency department. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100101
Suicide-related behaviors in older patients with new anti-epileptic drug use: data from the VA hospital system. BMC medicine 20100101
Jaw osteomyelitis as a complication in osteopetrosis. The Journal of craniofacial surgery 20100101
Human health risk assessment of pharmaceuticals in water: an uncertainty analysis for meprobamate, carbamazepine, and phenytoin. Regulatory toxicology and pharmacology : RTP 20100101
Effect of p-isopropoxyphenylsuccinimide monohydrate on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model. Pharmacological reports : PR 20100101
Development of antiepileptic hypersensitivity syndrome after phenytoin treatment. The Turkish journal of pediatrics 20100101
Synthesis and anticonvulsant activity of 4-oxo and 4-thioxo-8-bromobenzopyran derivatives. Arzneimittel-Forschung 20100101
Early predisposition to osteomalacia in Indian adults on phenytoin or valproate monotherapy and effective prophylaxis by simultaneous supplementation with calcium and 25-hydroxy vitamin D at recommended daily allowance dosage: a prospective study. Neurology India 20100101
Multifocal Stevens-Johnson syndrome after concurrent phenytoin and cranial and thoracic radiation treatment, a case report. Radiation oncology (London, England) 20100101
Oral dosing requirements for phenytoin in the first three months of life. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique 20100101
Profile of post-traumatic epilepsy in Benin City, Nigeria. West African journal of medicine 20100101
Pharmacological interventions for antisocial personality disorder. The Cochrane database of systematic reviews 20100101
Assessment of the effect of phenytoin on cutaneous healing from excision of melanocytic nevi on the face and on the back. BMC dermatology 20100101
Phenytoin dependence syndrome: a case report. The Journal of neuropsychiatry and clinical neurosciences 20100101
Phenytoin toxicity secondary to an oxcarbazepine-phenytoin 2C19 interaction. Psychosomatics 20100101
Diphenylhydantoin-induced severe yet reversible anemia during pregnancy. Internal medicine (Tokyo, Japan) 20100101
Influence of ethacrynic acid on the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock seizure model. Pharmacological reports : PR 20100101
A sensitive and selective HPLC method for estimation of lamotrigine in human plasma and saliva: application to plasma-saliva correlation in epileptic patients. Arzneimittel-Forschung 20100101
Epilepsy (generalised). BMJ clinical evidence 20100101
Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: Implication for bipolar depression treatment. Behavioural brain research 20091228
Autoantibodies to glutamate receptor GluRepsilon2 in a patient with limbic encephalitis associated with relapsing polychondritis. Journal of the neurological sciences 20091215
Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats. Brain research 20091208
CYP2C9, CYP2C19, and ABCB1 genotype and hospitalization for phenytoin toxicity. Journal of clinical pharmacology 20091201
Assessment of inter-individual variability in predicted phenytoin clearance. European journal of clinical pharmacology 20091201
Design of porous microparticles with single-micron size by novel spray freeze-drying technique using four-fluid nozzle. International journal of pharmaceutics 20091201
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered]. Gastroenterologia y hepatologia 20091201
Anticonvulsant use and outcomes after intracerebral hemorrhage. Stroke 20091201
Effect of repeated administration of Annona diversifolia Saff. (ilama) extracts and palmitone on rat amygdala kindling. Epilepsy & behavior : E&B 20091201
Blood pressure changes after intravenous fosphenytoin and levetiracetam in patients with acute cerebral symptoms. Epilepsy research 20091201
Utility of levetiracetam in patients with subarachnoid hemorrhage. Seizure 20091201
Cyclosporin A and phenytoin modulate inflammatory responses. Journal of dental research 20091201
Synthesis of 8-substituted-4-(2/4-substituted phenyl)-2H-[1,3,5]triazino[2,1-b][1,3]benzothiazole-2-thiones and their anticonvulsant, anti-nociceptive, and toxicity evaluation in mice. Journal of enzyme inhibition and medicinal chemistry 20091201
The spectrum of abnormal neurologic outcomes subsequent to term intrapartum asphyxia. Pediatric neurology 20091201
What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam? Epilepsia 20091201
Minimum requirements for approval of a drug in status epilepticus. Epilepsia 20091201
Valproic acid: long-term effects on children exposed in utero. Prescrire international 20091201
Phenytoin-induced DRESS. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20091201
Pearls & oy-sters: soft-tissue necrosis as a result of intravenous leakage of phenytoin. Neurology 20091110
Contraindications to phenytoin in emergency department patients with seizures. The Journal of emergency medicine 20091101
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study. Anesthesia and analgesia 20091101
Craniotomy pain: trying to do better. Anesthesia and analgesia 20091101
Effect of pharmacist participation in the health care team on therapeutic drug monitoring utilization for antiepileptic drugs. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091101
[Ophthalmoplegia produced by phenytoin]. Neurologia (Barcelona, Spain) 20091101
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore. Bioorganic & medicinal chemistry 20091001
Antiulcer and anticonvulsant activity of Croton zambesicus. Pakistan journal of pharmaceutical sciences 20091001
Nanosizing of poorly water soluble compounds using rotation/revolution mixer. Chemical & pharmaceutical bulletin 20091001
The little compound that could: how phenytoin changed drug discovery and development. Molecular interventions 20091001
Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy. Annals of the New York Academy of Sciences 20091001
Phenytoin toxicity and thyroid dysfunction. The New Zealand medical journal 20090925
Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities. European journal of medicinal chemistry 20090901
Influence of the preparation procedure and chitosan type on physicochemical properties and release behavior of alginate-chitosan microparticles. Drug development and industrial pharmacy 20090901
The use of antiepileptic drugs in pediatric brain tumor patients. Pediatric neurology 20090901
Should enzyme-inducing antiepileptic drugs be considered first-line agents? Epilepsia 20090901
Phenytoin-induced reduction of voriconazole serum concentration is not compensated by doubling the dosage. British journal of clinical pharmacology 20090901
Evaluation and refinement of euthanasia methods for Xenopus laevis. Journal of the American Association for Laboratory Animal Science : JAALAS 20090901
Phenytoin enhances collagenization in excision wounds and tensile strength in incision wounds. Die Pharmazie 20090901
Skin biopsies to assess response to systemic corticosteroid therapy in early-stage TEN: case report and review of the literature. Cutis 20090901
Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice. Methods and findings in experimental and clinical pharmacology 20090901
[Influence of scorpion alcoholic extraction on mdr1 mRNA and P-gp expression in brain of phenytoin-resistant convulsive rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901
Differences between the measured and calculated free serum phenytoin concentrations in epileptic patients. Yonsei medical journal 20090831
Termination of complex partial status epilepticus by intravenous levetiracetam. Journal of neurology, neurosurgery, and psychiatry 20090801
Drug-associated linear IgA disease mimicking toxic epidermal necrolysis. Clinical and experimental dermatology 20090801
Sodium channel activity modulates multiple functions in microglia. Glia 20090801
Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090801
The effects of propofol infusion on hepatic and pancreatic function and acid-base status in children undergoing craniotomy and receiving phenytoin. Anesthesia and analgesia 20090801
Nephrotic-range proteinuria with small glomerular fibrillary deposits in a patient on diphenylhydantoin treatment. Medical science monitor : international medical journal of experimental and clinical research 20090801
Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteers. British journal of clinical pharmacology 20090801
Guidelines for diagnosis and management of childhood epilepsy. Indian pediatrics 20090801
[A case of drug-induced interstitial pneumonia due to phenytoin]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20090801
Biopsy-proven immune reconstitution syndrome in a patient with AIDS and cerebral toxoplasmosis. Neurology 20090728
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Traditional Chinese medicine for epilepsy. The Cochrane database of systematic reviews 20090708
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Evaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs. Drug metabolism and disposition: the biological fate of chemicals 20090701
Characterization of the binding of drugs to human intestinal fatty acid binding protein (IFABP): potential role of IFABP as an alternative to albumin for in vitro-in vivo extrapolation of drug kinetic parameters. Drug metabolism and disposition: the biological fate of chemicals 20090701
N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model. Neuroscience research 20090701
Basal ganglia involvement in a child with herpes simplex encephalitis. Indian journal of pediatrics 20090701
Anticonvulsant effect of Ficus religiosa: role of serotonergic pathways. Journal of ethnopharmacology 20090622
Molecularly imprinted polymers for simultaneous determination of antiepileptics in river water samples by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20090619
Agranulocytosis following phenytoin-induced hypersensitivity syndrome. Brain & development 20090601
CYP2C9 amino acid residues influencing phenytoin turnover and metabolite regio- and stereochemistry. The Journal of pharmacology and experimental therapeutics 20090601
Neuroprotective effects of diazepam, carbamazepine, phenytoin and ketamine after pilocarpine-induced status epilepticus. Basic & clinical pharmacology & toxicology 20090601
Headache as the initial manifestation of neurocysticercosis: a case of eosinophilic meningitis. Headache 20090601
Polymyoclonus seizure resulting from accidental injection of tranexamic acid in spinal anesthesia. Anesthesia and analgesia 20090601
Fosphenytoin. Expert opinion on drug metabolism & toxicology 20090601
Intestinal obstruction and phenytoin intoxication. Pediatrics international : official journal of the Japan Pediatric Society 20090601
[Research advances in the mechanism of phenytoin-induced gingival overgrowth]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090601
New antiepileptic drugs: molecular targets. Central nervous system agents in medicinal chemistry 20090601
Enhanced synaptic vesicle traffic in hippocampus of phenytoin-resistant kindled rats. Neurochemical research 20090501
Benign familial neonatal convulsions: novel mutation in a newborn. Pediatric neurology 20090501
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. The New England journal of medicine 20090416
Case 3-2009: a 9-month-old boy with seizures. The New England journal of medicine 20090409
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[Drugs for status epilepticus treatment]. Revue neurologique 20090401
Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H(2)O(2). Water research 20090401
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Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research 20090401
Neurocysticercosis in a patient in Canada. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20090317
A case of Listeria meningoencephalitis complicated by hydrocephalus in an immunocompetent infant. European journal of pediatrics 20090301
Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings. Neurochemical research 20090301
Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions. Xenobiotica; the fate of foreign compounds in biological systems 20090301
Drug treatment of epilepsy in the century of the ILAE: the first 50 years, 1909-1958. Epilepsia 20090301
Phenytoin toxicity masquerading as motor neurone disease. Anaesthesia 20090301
Effect of sodium phenytoin concentration on neural tube development in the early stages of chicken embryo development. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090201
Dose adjustment of phenytoin for comedication in Japanese patients with epilepsy. Therapeutic drug monitoring 20090201
Preventing and treating posttraumatic seizures: the human experience. Epilepsia 20090201
Emergency treatment of status epilepticus: current thinking. Emergency medicine clinics of North America 20090201
Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device. Lab on a chip 20090121
Images in clinical medicine. Medication-induced gingival hypertrophy. The New England journal of medicine 20090108
A case of refractory secondary paroxysmal kinesigenic dyskinesia with high sensitivity to phenytoin monotherapy. Parkinsonism & related disorders 20090101
Synthesis and potential anticonvulsant activity of new N-3-substituted 5,5-cyclopropanespirohydantoins. European journal of medicinal chemistry 20090101
Leukopenia and thrombocytopenia on adding aripiprazole to phenytoin. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007. QJM : monthly journal of the Association of Physicians 20090101
Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons. Epilepsy research 20090101
Phenytoin toxicity due to genetic polymorphism. Neurocritical care 20090101
Drug interaction studies with dexlansoprazole modified release (TAK-390MR), a proton pump inhibitor with a dual delayed-release formulation: results of four randomized, double-blind, crossover, placebo-controlled, single-centre studies. Clinical drug investigation 20090101
Granulomatous interstitial nephritis after prolonged use of phenytoin. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090101
The impact of topical phenytoin on recalcitrant neuropathic diabetic foot ulceration. Journal of wound care 20090101
Evaluation of human plasma protein binding of trabectedin (Yondelis, ET-743). Current clinical pharmacology 20090101
[Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years]. Brain and nerve = Shinkei kenkyu no shinpo 20090101
Mandibular bone density and calcium content affected by long-term anticonvulsant treatment in rats. Journal of musculoskeletal & neuronal interactions 20090101
Diphenylhydantoin plays a role in gene expression related to cytoskeleton and protein adhesion in human normal palate fibroblasts. Pathology 20090101
Antiepileptic hypersensitivity and DRESS syndrome due to phenytoin in two pediatric cases. The Turkish journal of pediatrics 20090101
Life-threatening cardiotoxicity due to chronic oral phenytoin overdose. Neurology India 20090101
Trigeminal neuralgia. BMJ clinical evidence 20090101
Bone disease induced by phenytoin therapy: clinical and experimental study. European neurology 20090101
Bilateral anterior cerebral artery infarction following viper bite. The Journal of the Association of Physicians of India 20090101
Determination of phenytoin and its major metabolite in human serum by MEKC. Journal of chromatographic science 20090101
[Anticonvulsants as bioantioxidants under stress conditions]. Biomeditsinskaia khimiia 20090101
Lupus cerebritis after visiting a tanning salon. Bulletin of the NYU hospital for joint diseases 20090101
FDA: Epilepsy drugs may carry skin risks for Asians. JAMA 20081224
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population. Epilepsia 20081201
Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs. Toxicology in vitro : an international journal published in association with BIBRA 20081201
A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens. Clinica chimica acta; international journal of clinical chemistry 20081201
Severe postictal laryngospasm as a potential mechanism for sudden unexpected death in epilepsy: a near-miss in an EMU. Epilepsia 20081201
Treatment of severe intravenous phenytoin overdose with hemodialysis and hemoperfusion. Medical science monitor : international medical journal of experimental and clinical research 20081201
Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10). Cancer letters 20081128
Anticonvulsant activity of Carissa edulis (Vahl) (Apocynaceae) root bark extract. Journal of ethnopharmacology 20081120
Phenytoin protects central axons in experimental autoimmune encephalomyelitis. Journal of the neurological sciences 20081115
Formulation and in vitro and in vivo characterization of a phenytoin self-emulsifying drug delivery system (SEDDS). European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115
Phenytoin intoxication in a clozapine-related prolonged seizure. The Journal of emergency medicine 20081101
Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series. European eating disorders review : the journal of the Eating Disorders Association 20081101
Including information on the therapeutic window in bioequivalence acceptance. Pharmaceutical research 20081101
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. Epilepsy research 20081101
Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus. Epilepsy research 20081101
Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin. Acta neurologica Scandinavica 20081101
Therapeutic drug monitoring of phenytoin in critically ill patients. Pharmacotherapy 20081101
A case of venlafaxine-induced galactorrhea? Journal of clinical psychopharmacology 20081001
Fatal errors with cerebyx. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20081001
Levetiracetam versus phenytoin for seizure prophylaxis in severe traumatic brain injury. Neurosurgical focus 20081001
[Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia]. Medicina intensiva 20081001
Drug use in porphyria: a therapeutic dilemma. Singapore medical journal 20081001
Effect of phenytoin and valproic acid therapy on serum lipid levels and liver function tests. Indian pediatrics 20081001
Isaacs syndrome. British journal of hospital medicine (London, England : 2005) 20081001
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography. Journal of pharmaceutical and biomedical analysis 20080929
Simultaneous toxicities in a child on multiple anticonvulsants. Journal of child neurology 20080901
Refractory status epilepticus during pregnancy secondary to cavernous angioma. Epilepsia 20080901
Coated carbon hemoperfusion provides limited clearance of protein-bound solutes. Artificial organs 20080901
Fulminant myopericarditis from phenytoin-induced systemic lupus erythematosus. WMJ : official publication of the State Medical Society of Wisconsin 20080901
Audit of treatment of convulsive status epilepticus. The Ceylon medical journal 20080901
Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery. Neurology 20080826
Levetiracetam as a possible cause of fulminant liver failure. Neurology 20080826
Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedicine : international journal of phytotherapy and phytopharmacology 20080801
The first case of phenytoin intoxication associated with the concomitant use of phenytoin and TS-1, a combination preparation of tegafur, gimeracil, and oteracil potassium. Cancer chemotherapy and pharmacology 20080801
Aromatic antiepileptic drugs and mitochondrial toxicity: effects on mitochondria isolated from rat liver. Toxicology in vitro : an international journal published in association with BIBRA 20080801
Chronic developmental exposure to phenytoin has long-term behavioral consequences. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080801
Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin. Drug metabolism and disposition: the biological fate of chemicals 20080801
Association between SCN1A polymorphism and carbamazepine-resistant epilepsy. British journal of clinical pharmacology 20080801
Pharmacokinetic-pharmacodynamic modeling of the influence of chronic phenytoin therapy on the rocuronium bromide response in patients undergoing brain surgery. European journal of clinical pharmacology 20080801
Effects of a static magnetic field on audiogenic seizures in black Swiss mice. Epilepsy research 20080801
Phenytoin metabolite renal calculus: an index case. Journal of endourology 20080801
Elevated thyroid-stimulating hormone in a 65-year-old patient with phenytoin toxicity. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20080801
Oral medicine case book 10. Gingival diseases. SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20080801
Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain. Journal of the neurological sciences 20080715
Development of tolerance to levetiracetam in rats with chronic epilepsy. Epilepsia 20080701
Additional phenytoin is frequently needed in patients undergoing craniotomy for supratentorial tumour. European journal of anaesthesiology 20080701
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models. Epilepsia 20080701
Status epilepticus in central nervous system infections: an experience from a developing country. The American journal of medicine 20080701
Pharmacological modulation of cortical plasticity following kainic acid lesion in rat barrel cortex. Journal of neurosurgery 20080701
Phenytoin half-life and clearance during maintenance therapy in adults and elderly patients with epilepsy. Neurology 20080701
Phenytoin intoxication and upper facial dyskinesia: an unusual presentation. Movement disorders : official journal of the Movement Disorder Society 20080615
Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts. Molecular reproduction and development 20080601
Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy. Brain & development 20080601
Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug events. Journal of clinical epidemiology 20080601
Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin. Bioorganic & medicinal chemistry 20080601
Erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080601
Generalized tonic-clonic seizures after acute oxcarbazepine withdrawal. Neurology 20080527
Myotoxicity studies of O/W-in situ forming microparticle systems. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501
Severe graft failure presumably due to phenytoin-induced hypersensitivity syndrome in two patients after bone marrow transplantation. Bone marrow transplantation 20080501
The 'albumin effect' and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9. Drug metabolism and disposition: the biological fate of chemicals 20080501
Delineation of the phenotype associated with 7q36.1q36.2 deletion: long QT syndrome, renal hypoplasia and mental retardation. American journal of medical genetics. Part A 20080501
The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons. Epilepsy research 20080501
Evaluation of brain and whole-body pharmacokinetics of 11C-labeled diphenylhydantoin in rats by means of planar positron imaging system. Annals of nuclear medicine 20080501
Antiepileptic drugs and thyroid function. Journal of pediatric endocrinology & metabolism : JPEM 20080501
Phenytoin induced severe disabling osteomalacia in a young male with seizure disorder. The Journal of the Association of Physicians of India 20080501
Bone health. Neurology 20080429
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy. Neurology 20080429
Aconitine induces prolonged seizure-like events in rat neocortical brain slices. European journal of pharmacology 20080428
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro. Neuroscience letters 20080404
Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. European journal of clinical pharmacology 20080401
Clinical trial: a dose-response study of fospropofol disodium for moderate sedation during colonoscopy. Alimentary pharmacology & therapeutics 20080401
Effect of phenytoin on celecoxib pharmacokinetics in patients with glioblastoma. Neuro-oncology 20080401
Phenytoin toxicity: an easily missed cause of cerebellar syndrome. Journal of clinical pharmacy and therapeutics 20080401
A confusing case of confusion. Acute porphyrias. The Journal of the Oklahoma State Medical Association 20080401
Changes in gene expression induced by carbamazepine and phenytoin: testing the danger hypothesis. Journal of immunotoxicology 20080401
[Biological effects of phenytoin on cultured human periodontal ligament fibroblasts in vitro]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20080401
Acenocoumarol and phenytoin toxicity in the presence of CYP2C9 mutation. The Journal of the Association of Physicians of India 20080401
Phenytoin but not valproate directly affected in vitro trophoblast differentiation. European journal of obstetrics, gynecology, and reproductive biology 20080301
Albendazole therapy for single small enhancing CT lesions (SSECTL) in the brain in epilepsy. Journal of neurology, neurosurgery, and psychiatry 20080301
Undetectable phenytoin serum levels by an automated particle-enhanced turbidimetric inhibition immunoassay in a patient with monoclonal IgM lambda. Clinica chimica acta; international journal of clinical chemistry 20080301
Temporal pattern of oxcarbazepine and phenytoin withdrawal seizures during epilepsy monitoring. Epilepsy research 20080301
Antiepileptic drugs as human teratogens. Expert opinion on drug safety 20080301
Postictal transient hyperammonemia. The American journal of emergency medicine 20080301
Rapid determination of the damage to photosynthesis caused by salt and osmotic stresses using delayed fluorescence of chloroplasts. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080301
Case of the month: drug-induced hyperplasia. Today's FDA : official monthly journal of the Florida Dental Association 20080301
Analytical followup of the gamma initiated synthesis of a molecularly imprinted polymer. Analytica chimica acta 20080211
Pharmacokinetics of midazolam and metabolites in a patient with refractory status epilepticus treated with extraordinary doses of midazolam. Therapeutic drug monitoring 20080201
The humble electrocardiogram. Practical neurology 20080201
Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study. The Lancet. Neurology 20080201
Soft-tissue surgery: use of the Er,Cr:YSGG laser. Dentistry today 20080201
Re: New lessons: classic treatments in convulsive status epilepticus. Irish medical journal 20080201
Exanthematous allergic drug reactions due to four chemically unrelated drugs. Dermatology online journal 20080115
Clinical interaction between efavirenz and phenytoin. AIDS (London, England) 20080102
Statins and phenytoin interact - a case history. British journal of clinical pharmacology 20080101
Hepatocyte transplantation and drug-induced perturbations in liver cell compartments. Hepatology (Baltimore, Md.) 20080101
Pharmacokinetics of phenytoin and its metabolite, 4'-HPPH, after intravenous and oral administration of phenytoin to diabetic rats induced by alloxan or streptozotocin. Biopharmaceutics & drug disposition 20080101
Aggressive CNS lupus vasculitis in the absence of systemic disease activity. Rheumatology (Oxford, England) 20080101
The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator. Cerebrovascular diseases (Basel, Switzerland) 20080101
Preliminary findings from the National Register of Antipsychotic Medication in Pregnancy. The Australian and New Zealand journal of psychiatry 20080101
Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. Pharmacotherapy 20080101
Effects of cyclosporin, phenytoin, and nifedipine on the synthesis and degradation of gingival collagen in tufted capuchin monkeys (Cebus apella): histochemical and MMP-1 and -2 and collagen I gene expression analyses. Journal of periodontology 20080101
Structure and anti-proliferation function of 5,5-diphenyl-2-thiohydantoin (DPTH) derivatives in vascular endothelial cells. Vascular pharmacology 20080101
Severe phenytoin-induced gingival enlargement associated with periodontitis. General dentistry 20080101
A case of hypersensitivity syndrome due to phenytoin. Journal of investigational allergology & clinical immunology 20080101
Ineffectiveness of folic acid supplementation against phenytoin-induced decrease in salivary immunoglobulin A concentration of epileptic patients. European neurology 20080101
Effects of etoricoxib on the pharmacokinetics of phenytoin. Pharmacological reports : PR 20080101
High-throughput study of phenytoin solid dispersions: formulation using an automated solvent casting method, dissolution testing, and scaling-up. Journal of combinatorial chemistry 20080101
Influence of burns on pharmacokinetics and pharmacodynamics of drugs used in the care of burn patients. Clinical pharmacokinetics 20080101
Acute intermittent porphyria: diagnosis per chance. Indian journal of pathology & microbiology 20080101
Therapeutic drug monitoring of antiepileptic drugs. JNMA; journal of the Nepal Medical Association 20080101
Antiepileptic drugs in aneurysmal subarachnoid hemorrhage. Reviews in neurological diseases 20080101
Synthesis and anticonvulsant activity of 5-chloro-2(3H)-benzoxazolinone-3-acetyl-2-(o/p-substituted benzal) hydrazone derivatives. Arzneimittel-Forschung 20080101
Capgras syndrome and unilateral spatial neglect in nonconvulsive status epilepticus. Behavioural neurology 20080101
Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model. Psychopharmacology 20071201
Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex. Epilepsy research 20071201
Three-day phenytoin prophylaxis is adequate after subarachnoid hemorrhage. Neurosurgery 20071201
Rotavirus-induced seizures in childhood. Journal of child neurology 20071201
Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock. European journal of pharmacology 20071114
Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial. Spinal cord 20071101
Phenytoin desensitization monitored by antigen specific T cell response using carboxyfluorescein succinimidyl ester dilution assay. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20071101
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury. The American journal of gastroenterology 20071101
Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination. Drug metabolism and disposition: the biological fate of chemicals 20071101
The clinical effect of topical phenytoin on wound healing: a systematic review. The British journal of dermatology 20071101
Preliminary explorations of the role of mitochondrial proteins in refractory epilepsy: some findings from comparative proteomics. Journal of neuroscience research 20071101
Preparation and characterisation of phenytoin-loaded alginate and alginate-chitosan microparticles. Drug delivery 20071101
The effect of gabapentin and phenytoin on sperm-morphology in Wistar rats. Reproductive biology 20071101
Benign intracranial hypotension. The Journal of the Association of Physicians of India 20071101
[Deadly drug interactions]. Nihon rinsho. Japanese journal of clinical medicine 20071028
Psychotropic effects of antiepileptic drugs. Neurology 20071016
Seizure and prominent abdominal veins. Lancet (London, England) 20071006
Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism. Epilepsia 20071001
Physical incompatibility of phenytoin with Isolyte P. Journal of neurosurgical anesthesiology 20071001
Fatal phenytoin-induced thrombocytopaenia in a neurosurgical patient. European journal of anaesthesiology 20071001
Intravenous phenytoin and percutaneous arterial cannulation: the purple-glove syndrome. European journal of anaesthesiology 20071001
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915
Significant drug interaction: phenytoin toxicity due to erlotinib. Lung cancer (Amsterdam, Netherlands) 20070901
Stereoselective glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin by human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: effects of UGT-UGT interactions. Drug metabolism and disposition: the biological fate of chemicals 20070901
Randomized study of intravenous valproate and phenytoin in status epilepticus. Seizure 20070901
[Toxic epidermal necrolysis induced by phenytoin and whole brain radiotherapy]. Actas dermo-sifiliograficas 20070901
Apoptosis in gingival overgrowth tissues. Journal of dental research 20070901
Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome. Pediatric emergency care 20070901
[Drug-induced hypersensitivity due to phenytoin]. No to hattatsu = Brain and development 20070901
A painful gum. Australian family physician 20070901
Drug interactions between tacrolimus and phenytoin in Japanese heart transplant recipients: 2 case reports. International journal of clinical pharmacology and therapeutics 20070901
Topical diphenylhydantoin sodium can improve healing in a diabetic incisional animal wound model. Journal of wound care 20070901
Effect of doses on the bioavailability of phenytoin from a prompt-release and an extended-release preparation: single dose study. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070901
[Influence of repeated seizures and large dosage anti-epileptic drug on phosphorylated cAMP response element binding protein in rat's hippocampus and effect of Caoguo Zhimu Decoction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070901
[Adverse effects of therapeutic drugs on peripheral nervous system]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810
[Neuromuscular disorders caused by adverse effects of antiepileptics]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810
Effects of phenytoin and carbamazepine on calcium transport in Caco-2 cells. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain. The Journal of pharmacology and experimental therapeutics 20070801
The natural history and treatment of epilepsy in a murine model of tuberous sclerosis. Epilepsia 20070801
Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway. The Journal of pharmacology and experimental therapeutics 20070801
Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity. Birth defects research. Part A, Clinical and molecular teratology 20070801
Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock. Epilepsy & behavior : E&B 20070801
Non-convulsive status epilepticus secondary to valproic acid-induced hyperammonemic encephalopathy. Acta neurologica Scandinavica 20070801
Status epilepticus associated with sertindole. European journal of neurology 20070801
Estimation of drug precipitation upon dilution of pH-cosolvent solubilized formulations. Chemical & pharmaceutical bulletin 20070801
Possible mechanisms for the pharmacokinetic interaction between phenytoin and folinate in rats. Therapeutic drug monitoring 20070801
Neonatal seizures: multicenter variability in current treatment practices. Pediatric neurology 20070801
Anticonvulsant hypersensitivity syndrome. The Journal of emergency medicine 20070801
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model. European journal of pharmacology 20070712
Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis. European journal of pharmacology 20070712
Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats. The Journal of pharmacology and experimental therapeutics 20070701
Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy. Epilepsia 20070701
Rash from antiepileptic drugs: influence by gender, age, and learning disability. Epilepsia 20070701
Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20070701
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs. Reproductive toxicology (Elmsford, N.Y.) 20070701
Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine. Annals of neurology 20070701
An ImmunoChip prototype for simultaneous detection of antiepileptic drugs using an enhanced one-step homogeneous immunoassay. Analytical biochemistry 20070615
Superior oblique myokymia: efficacy of medical treatment. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20070601
Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ecto-nucleotidases. Neurochemical research 20070601
Anticonvulsant therapy for status epilepticus. British journal of clinical pharmacology 20070601
Allergen-specific T-cell response in patients with phenytoin hypersensitivity; simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester (CFSE) dilution assay. Allergology international : official journal of the Japanese Society of Allergology 20070601
Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study. Therapeutic drug monitoring 20070601
Fractionated stereotactic radiotherapy boost and weekly paclitaxel in malignant gliomas clinical and pharmacokinetics results. Technology in cancer research & treatment 20070601
Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men. Current medical research and opinion 20070601
Reduction of hippocampal CA 1 neurons in Wistar rats following the administration of phenytoin for seven days. African journal of medicine and medical sciences 20070601
Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting. Journal of biochemistry and molecular biology 20070531
Concentration gradient immunoassay. 1. An immunoassay based on interdiffusion and surface binding in a microchannel. Analytical chemistry 20070515
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro. Epilepsy research 20070501
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice. Journal of pharmacological sciences 20070501
Formulation of spray-dried phenytoin loaded poly(epsilon-caprolactone) microcarrier intended for brain delivery to treat epilepsy. Journal of pharmaceutical sciences 20070501
Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death. Pacing and clinical electrophysiology : PACE 20070501
Acute colchicine intoxication in a child: a case report. Pediatric emergency care 20070501
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia 20070501
Transient hypogammaglobulinemia after antiepileptic drug hypersensitivity. Pediatric neurology 20070501
[[Severe phenytoin intoxication in patients with hypoalbuminaemia]. Nederlands tijdschrift voor geneeskunde 20070428
[Subtherapeutic blood levels of phenytoin due to a medication error]. Praxis 20070425
Gender difference in the pharmacokinetic interaction between oral warfarin and oxolamine in rats: inhibition of CYP2B1 by oxolamine in male rats. Biopharmaceutics & drug disposition 20070401
Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy. Epilepsia 20070401
Macroprolactinomas and epilepsy. Clinical endocrinology 20070401
Phenytoin is not successful in preventing cocaine-induced seizures: a response to the article, 'Cocaine body packing in pregnancy'. Annals of emergency medicine 20070401
Intestinal expression of cytochrome P450 enzymes and ABC transporters and carbamazepine and phenytoin disposition. Acta neurologica Scandinavica 20070401
Clinical utility of a continuous intravenous infusion of valproic acid in pediatric patients. Pharmacotherapy 20070401
Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. Epilepsia 20070401
Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. Epilepsia 20070401
Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity. Human & experimental toxicology 20070401
Distal upper extremity edema and discoloration. American family physician 20070315
Phenytoin desensitization in a child with symptomatic localization-related epilepsy. Brain & development 20070301
A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile. Neuropharmacology 20070301
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration. Experimental brain research 20070301
Ocular therapeutics. Clinical & experimental optometry 20070301
Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs. Epilepsia 20070301
Drug treatment during pregnancy and isolated orofacial clefts in hungary. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20070301
Sodium valproate vs phenytoin in status epilepticus: a pilot study. Neurology 20070227
[Pharmacokinetic interaction between phenitoin and dexibuprofen resulting in acute neurologic toxicity]. Medicina clinica 20070217
Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model. Neuroscience letters 20070214
[Acquired common variable immunodeficiency syndrome induced by phenytoin]. Medicina clinica 20070210
Use of phenytoin, phenobarbital, or diazepam during pregnancy and risk of congenital abnormalities: a case-time-control study. Pharmacoepidemiology and drug safety 20070201
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology 20070201
Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20070201
Hypothesis of the cause and development of neoplasms. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20070201
Immunohistochemical evaluation of Ki-67 expression and apoptosis in cyclosporin A-induced gingival overgrowth. Journal of periodontology 20070201
Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese. Therapeutic drug monitoring 20070201
Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients. International journal of clinical pharmacology and therapeutics 20070201
Post-traumatic seizure disorder following acquired brain injury. Brain injury 20070201
Purple glove syndrome following intravenous phenytoin administration. Vascular medicine (London, England) 20070201
Epilepsy and antiepileptic drug use in elderly people as risk factors for dementia. Journal of the neurological sciences 20070131
Cerebral atrophy and skull thickening due to chronic phenytoin therapy. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070130
Therapeutic monitoring of antiepileptic drugs for epilepsy. The Cochrane database of systematic reviews 20070124
[Severe phenytoin intoxication in patients with hypoalbuminaemia]. Nederlands tijdschrift voor geneeskunde 20070113
Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers. The Journal of physiology 20070101
Does phenytoin play any role in prevention of Alzheimer's disease? Medical hypotheses 20070101
Is oral azithromycin effective for the treatment of phenytoin-induced gingival overgrowth in epileptic patients? Medical hypotheses 20070101
Phenytoin-potentiated hepatotoxicity following acetaminophen overdose? A closer look. Digestive diseases and sciences 20070101
Management of phenytoin toxicity in palliative care. Palliative medicine 20070101
The occurrence of clinical seizure under total intravenous anesthesia for a neurosurgical procedure. Anesthesia and analgesia 20070101
Acute laryngeal spasm. Emergency medicine journal : EMJ 20070101
Three-day phenytoin prophylaxis is adequate after subarachnoid hemorrhage. Neurosurgery 20070101
Neuropsychiatric manifestations of phenytoin toxicity in an elderly patient. Journal of psychiatric practice 20070101
Drug transporters in the epileptic brain. Epilepsia 20070101
Effect of chronic MK-801 and/or phenytoin on the acquisition of complex behaviors in rats. Neurotoxicology and teratology 20070101
Phenytoin immunoassay measurements in serum samples from patients with renal insufficiency: comparison with high-performance liquid chromatography. Journal of clinical laboratory analysis 20070101
Factors affecting antiepileptic drug pharmacokinetics in community-dwelling elderly. International review of neurobiology 20070101
Pharmacokinetics of antiepileptic drugs in elderly nursing home residents. International review of neurobiology 20070101
Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis. Journal of neurotrauma 20070101
Estimation of drug precipitation upon dilution of pH-controlled formulations. Molecular pharmaceutics 20070101
Phenytoin-induced toxic epidermal necrolysis in a neurosurgical patient. Neurology India 20070101
Delirium likely caused by interaction between phenytoin and temozolomide. Psychosomatics 20070101
[Anticonvulsants in the treatment of bipolar disorder]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20070101
Seizures and loss of vision in a patient with systemic lupus erythematosus. The Netherlands journal of medicine 20070101
Treatment of convulsive status epilepticus in infants and young children in Japan. Acta neurologica Scandinavica. Supplementum 20070101
Toxic-febrile neurobrucellosis, clinical findings and outcome of treatment of four cases based on our experience. Scandinavian journal of infectious diseases 20070101
Morbidity and mortality of mucocutaneous diseases in the pediatric population at a tertiary care center. Journal of burn care & research : official publication of the American Burn Association 20070101
Probing the non-covalent binding interaction of the Na+ channel inactivation gate peptide in a linker between domain III and IV with 5,5-diphenyhydantoin in electrospray ion trap tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Drug rash with eosinophilia and systemic symptoms syndrome: sex and the causative agent. Skinmed 20070101
Screening for the effects of antiepileptic drugs on short term plasticity using a time efficient bioassay. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20070101
Reperfusion seizures: a manifestation of cerebral reperfusion injury after administration of recombinant tissue plasminogen activator for acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101
Severe phenytoin toxicity in a CYP2C9*3*3 homozygous mutant from India. Neurology India 20070101
Measurement of recovery after traumatic brain injury: a cognitive-neuropsychological comparison of the WAIS-R with the cognitive assessment system (CAS) in a single case of atypical language lateralization. Applied neuropsychology 20070101
Dosing and therapeutic monitoring of phenytoin in young adults after neurotrauma: are current practices relevant? Clinical neuropharmacology 20070101
New lessons: Classic treatments in convulsive status epilepticus. Irish medical journal 20070101
How urgent is the treatment of nonconvulsive status epilepticus? Epilepsia 20070101
Clinical pharmacology of parenteral use of antiepileptic drugs. Epilepsia 20070101
[Caffeine and antiepileptic drugs: experimental and clinical data]. Przeglad lekarski 20070101
Phenytoin and carbamazepine delay the initial depression of the population spike upon exposure to in vitro ischemia and promote its post-ischemic functional recovery in rat hippocampal slices. European journal of pharmacology 20061228
The use of therapeutic plasmapheresis in the treatment of poisoned and snake bite victims: an academic emergency department's experiences. Journal of clinical apheresis 20061201
Vibrational spectra and normal coordinate analysis of diazepam, phenytoin and phenobarbitone. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201
Association of CYP2D6 100 C > T and 2850 C > T polymorphisms with generalized tonic clonic seizures among Indians. Journal of neural transmission (Vienna, Austria : 1996) 20061201
A comparison study of effects of Echinacea extract and levamisole on phenytoin-induced cleft palate in mice. Regulatory toxicology and pharmacology : RTP 20061201
Lamotrigine and phenytoin, but not amiodarone, impair peripheral chemoreceptor responses to hypoxia. Journal of applied physiology (Bethesda, Md. : 1985) 20061201
[Status epilepticus in a 2-month-old infant]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20061201
Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE. Brain : a journal of neurology 20061201
Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor. Drug metabolism and disposition: the biological fate of chemicals 20061201
CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles. Drug metabolism and disposition: the biological fate of chemicals 20061201
Phenytoin normalizes exaggerated fear behavior in p-chlorophenylalanine (PCPA)-treated rats. Epilepsy & behavior : E&B 20061201
Epilepsy, parkinsonism, and neuroleptic malignant syndrome in a child. Journal of child neurology 20061201
Vitamin E supplementation in phenytoin induced developmental toxicity in rats: postnatal study. Neuro endocrinology letters 20061201
Application of routine monitoring data for determination of the population pharmacokinetics and enteral bioavailability of phenytoin in neonates and infants with seizures. Therapeutic drug monitoring 20061201
Kaposi's varicelliform eruption in a patient with phenytoin-induced drug rash. International journal of dermatology 20061201
Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth. Journal of periodontology 20061201
Lipid lowering inefficacy of high-dose statin therapy due to concurrent use of phenytoin. Southern medical journal 20061201
Changes in plasma phenytoin level following craniotomy. British journal of neurosurgery 20061201
Polymorphic variants of the multidrug resistance gene Mdr1a and response to antiepileptic drug treatment in the kindling model of epilepsy. European journal of pharmacology 20061121
Phenytoin as an augmentation for SSRI failures: a small controlled study. Journal of affective disorders 20061101
Is phenytoin administration safe in a hypothermic child? Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20061101
Toxic epidermal necrolysis in a mother and fetus. Journal of the American Academy of Dermatology 20061101
Analysis of free drug fractions using near-infrared fluorescent labels and an ultrafast immunoextraction/displacement assay. Analytical chemistry 20061101
Phenytoin-induced parkinsonism. Singapore medical journal 20061101
Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy. Epilepsia 20061101
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101
Wound bed preparation with 10-percent phenytoin ointment increases the take of split-thickness skin graft in large diabetic ulcers. Dermatology online journal 20061031
Response to Zhou et al. Osteomalacia is a frequent complication resulting from long-term therapy with drugs such as phenytoin, carbamazepine, and phenobarbital. The Journal of clinical investigation 20061002
Phenytoin, an anti-bipolar anticonvulsant: a potential anti-glucocorticoid mechanism? The international journal of neuropsychopharmacology 20061001
An important functional role of persistent Na+ current in carotid body hypoxia transduction. Journal of applied physiology (Bethesda, Md. : 1985) 20061001
Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study. Journal of neurophysiology 20061001
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug metabolism and disposition: the biological fate of chemicals 20061001
Focal transient lesion in the splenium of the corpus callosum in three non-epileptic patients. Neuroradiology 20061001
Hyponatraemic convulsions and fatal head injury secondary to desmopressin treatment for enuresis. European journal of anaesthesiology 20061001
Hemodialysis and hemoperfusion in a patient with an isolated phenytoin overdose. The American journal of emergency medicine 20061001
A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose. Pharmacogenetics and genomics 20061001
Increased susceptibility to phenytoin teratogenicity: excessive generation of reactive oxygen species or impaired antioxidant defense? Basic & clinical pharmacology & toxicology 20061001
Development of a Drosophila seizure model for in vivo high-throughput drug screening. The European journal of neuroscience 20061001
Free phenytoin concentration measurement in brain extracellular fluid: a pilot study. British journal of neurosurgery 20061001
In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant. European journal of pharmacology 20060928
[Diabetes mellitus induced by drugs and chemical agents]. Nihon rinsho. Japanese journal of clinical medicine 20060928
Side by side comparison between dynamic versus static models of blood-brain barrier in vitro: a permeability study. Brain research 20060913
Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in atm knockout mice. Toxicological sciences : an official journal of the Society of Toxicology 20060901
Acetazolamide acts directly on the human skeletal muscle chloride channel. Muscle & nerve 20060901
Pattern of adverse drug reactions notified by spontaneous reporting in an Indian tertiary care teaching hospital. Pharmacological research 20060901
A developmental role for ataxia-telangiectasia mutated in protecting the embryo from spontaneous and phenytoin-enhanced embryopathies in culture. Toxicological sciences : an official journal of the Society of Toxicology 20060901
Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients. Epilepsy research 20060901
Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901
Phenytoin-induced DRESS with cross-reactivity to carbamazepine in a 10-year-old Indian child. Clinical and experimental dermatology 20060901
Interpretation of serum phenytoin concentrations: who would have thought that preventing and treating seizures were this challenging? Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901
[Familial clinical manifestation in patients with neuromesoectodermic defect]. Arquivos de neuro-psiquiatria 20060901
In utero antiepileptic drug exposure: fetal death and malformations. Neurology 20060808
Phenytoin: an anti-bipolar anticonvulsant? The international journal of neuropsychopharmacology 20060801
Effect of piperine on the steady-state pharmacokinetics of phenytoin in patients with epilepsy. Phytotherapy research : PTR 20060801
Effect of systemic and intracortical administration of phenytoin in two genetic models of absence epilepsy. British journal of pharmacology 20060801
[Neurological manifestations in critically ill patients]. Revista de neurologia 20060801
Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome. Journal of Korean medical science 20060801
Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients. Basic & clinical pharmacology & toxicology 20060801
The effect of local administration of phenytoin on fracture healing: an experimental study. Acta orthopaedica Belgica 20060801
Sodium valproate vs phenytoin in status epilepticus: a pilot study. Neurology 20060725
Life-threatening toxic epidermal necrolysis during voriconazole therapy for invasive aspergillosis after chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology 20060701
Nocardia abscess during treatment of brain toxoplasmosis in a patient with aids, utility of proton MR spectroscopy and diffusion-weighted imaging in diagnosis. Clinical neurology and neurosurgery 20060701
Topical phenytoin treatment in bimaxillary osteomyelitis secondary to infantile osteopetrosis: report of a case. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20060701
Cerebral venous sinus thrombosis presenting in the puerperium. Emergency medicine journal : EMJ 20060701
Cerebral venous thrombosis as a rare onset of Churg-Strauss syndrome. Thrombosis and haemostasis 20060701
Topical phenytoin ointment increases autograft acceptance in rats. Saudi medical journal 20060701
Purple glove syndrome associated with intravenous phenytoin administration in a patient with severe mental and motor retardation. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20060701
Nonlinear adsorption isotherm as a tool for understanding and characterizing molecularly imprinted polymers. Journal of chromatography. A 20060630
Benign angiopathy of the central nervous system associated with phenytoin intoxication. Brain & development 20060601
Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist. Neuropharmacology 20060601
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets. Endocrinology 20060601
Colonic involvement in Stevens-Johnson syndrome. Postgraduate medical journal 20060601
Effect of CYP2C19 genetic polymorphism on pharmacokinetics of phenytoin and phenobarbital in Japanese epileptic patients using Non-linear Mixed Effects Model approach. Journal of clinical pharmacy and therapeutics 20060601
Safety and efficacy of clobazam versus phenytoin-sodium in the antiepileptic drug treatment of solitary cysticercus granulomas. Neurology India 20060601
Seizure disorder in a professional American football player. Current sports medicine reports 20060601
A case of phenytoin toxicity in a patient with advanced lung cancer. Palliative medicine 20060601
Antiepileptic TDM pattern at a tertiary care hospital in India. Nepal Medical College journal : NMCJ 20060601
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy]. Ideggyogyaszati szemle 20060520
Studies by biointeraction chromatography of binding by phenytoin metabolites to human serum albumin. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060519
Solubilization behavior of a poorly soluble drug under combined use of surfactants and cosolvents. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501
Stevens-Johnson syndrome in two patients treated with cranial irradiation and phenytoin. Journal of the European Academy of Dermatology and Venereology : JEADV 20060501
Intrinsic bursting of immature CA3 pyramidal neurons and consequent giant depolarizing potentials are driven by a persistent Na+ current and terminated by a slow Ca2+ -activated K+ current. The European journal of neuroscience 20060501
Transient occipitotemporal subcortical diffusion-weighted magnetic resonance imaging abnormalities associated with status epilepticus. Case report. Neurologia medico-chirurgica 20060501
Correlation of retention factor of analytes in quaternary solvent mobile phases using the Jouyban-Acree model. Die Pharmazie 20060501
[Odinophagia and cutaneous lesions in patient with cerebral metastases]. Revista clinica espanola 20060501
[An animal model of antiepileptic-induced osteoporosis in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060501
Pharmacogenomic studies: hype and reality. The Indian journal of medical research 20060501
Influence of the CYP2C9 AND CYP2C19 polymorphisms on phenytoin hydroxylation in healthy individuals from south India. The Indian journal of medical research 20060501
Oxcarbazepine versus phenytoin monotherapy for epilepsy. The Cochrane database of systematic reviews 20060419
Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats. Epilepsia 20060401
Epileptic seizures superimposed on catatonic stupor. Epilepsia 20060401
Phenytoin. Nursing times 20060401
Application of highly accurate nephelometric titration in the assaying of phenytoin sodium. Yao xue xue bao = Acta pharmaceutica Sinica 20060401
[Hypersensitivity syndrome to phenitoin]. Anales de medicina interna (Madrid, Spain : 1984) 20060401
Hepatic encephalopathy with status epileptics: a case report. World journal of gastroenterology 20060321
[Phenytoin induced deep venous thrombosis]. Medicina clinica 20060318
Clinical evaluation of plasma free phenytoin measurement and factors influencing its protein binding. Biopharmaceutics & drug disposition 20060301
Differences in the allosteric modulation by phenytoin of the binding properties of the sigma1 ligands [3H](+)-pentazocine and [3H]NE-100. Synapse (New York, N.Y.) 20060301
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6. Seizure 20060301
Preliminary evaluation of polymer-based drug composite microparticle production by coacervate desolvation with supercritical carbon dioxide. Journal of pharmaceutical sciences 20060301
Effect of phenytoin on collagen accumulation by human gingival fibroblasts exposed to TNF-alpha in vitro. Oral diseases 20060301
Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. Prostaglandins, leukotrienes, and essential fatty acids 20060301
Starry sky and beaded legs. The Lancet. Infectious diseases 20060301
Determination of phenytoin sodium injection and tablets by highly accurate nephelometric titration. Chemical & pharmaceutical bulletin 20060301
[Intramuscular midazolam in the initial treatment of status epilepticus]. Revista de neurologia 20060301
Effects of artemisinin, artemether, and arteether on the pharmacokinetics of phenytoin. Methods and findings in experimental and clinical pharmacology 20060301
Physical growth and psychomotor development of infants exposed to antiepileptic drugs in utero. Neurology India 20060301
Seizure presenting to the emergency department, Srinagarind Hospital. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060301
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20060301
2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice. European journal of pharmacology 20060215
Phenytoin can accelerate the healing process after experimental myocardial infarction? International journal of cardiology 20060208
Use of compressed gas precipitation to enhance the dissolution behavior of a poorly water-soluble drug: generation of drug microparticles and drug-polymer solid dispersions. International journal of pharmaceutics 20060203
Formation of phenytoin nanoparticles using rapid expansion of supercritical solution with solid cosolvent (RESS-SC) process. International journal of pharmaceutics 20060203
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model. Neuropharmacology 20060201
Ten things we hate about subarachnoid hemorrhage (or, the taming of the aneurysm). Critical care medicine 20060201
When benzodiazepines fail: how effective is second line therapy for status epilepticus in children? Emergency medicine Australasia : EMA 20060201
Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions. The Journal of allergy and clinical immunology 20060201
Dural sinus thrombosis in melioidosis: the first case report. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060201
Pharmacological and clinical aspects of antiepileptic drug use in the elderly. Epilepsy research 20060101
Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in rat plasma. Drug metabolism and disposition: the biological fate of chemicals 20060101
Vitamin K deficiency in children pre-bone marrow transplantation. Bone marrow transplantation 20060101
The antiepileptic drug phenytoin affects sodium transport in toad epithelium. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060101
Anti-epileptic drug phenytoin enhances androgen metabolism and androgen receptor expression in murine hippocampus. Journal of neurochemistry 20060101
Cortical laminar necrosis related to prolonged focal status epilepticus. Journal of neurology, neurosurgery, and psychiatry 20060101
Pseudolymphoma syndrome: findings on a gallium-67 citrate scan. Clinical nuclear medicine 20060101
Periodontal and soft tissue prevention strategies for the adolescent dental patient. Dental clinics of North America 20060101
Introduction to the International Geriatric Epilepsy Symposium (IGES). Epilepsy research 20060101
Relationship of periodontal bacteria and Porphyromonas gingivalis fimA variations with phenytoin-induced gingival overgrowth. Oral diseases 20060101
Fosphenytoin may cause hemodynamically unstable bradydysrhythmias. The Journal of emergency medicine 20060101
SAMMA induces premature human acrosomal loss by Ca2+ signaling dysregulation. Journal of andrology 20060101
The relationship between cleft lip, maxillary hypoplasia, hypoxia and phenytoin. Current pharmaceutical design 20060101
[Update on current care guidelines. Prolonged epileptic attack]. Duodecim; laaketieteellinen aikakauskirja 20060101
Prolonged use of phenytoin, carbamazepine or valproate monotherapy on plasma levels of folate and B(12): a comparison between epileptic patients with or without cardiovascular disorders. Neuro endocrinology letters 20060101
Evaluation of three different specimen types (serum, plasma lithium heparin and serum gel separator) for analysis of certain analytes: clinical significance of differences in results and efficiency in use. Clinical chemistry and laboratory medicine 20060101
Anticonvulsant effect of amiloride in pentetrazole-induced status epilepticus in mice. Pharmacological reports : PR 20060101
Can phenytoin prevent Alzheimer's disease? Medical hypotheses 20060101
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis. Medical hypotheses 20060101
Ceftazidime overdose-related nonconvulsive status epilepticus after intraperitoneal instillation. Clinical toxicology (Philadelphia, Pa.) 20060101
Effects of basic fibroblast growth factor and phenytoin on healing of abdominal wall fascia and colonic anastomoses. International surgery 20060101
Diphenylhydantoin-induced pure red cell aplasia. Journal of the Indian Medical Association 20060101
Epilepsy in the elderly. Epilepsia 20060101
Chronotherapeutic dose schedule of phenytoin and carbamazepine in epileptic patients. Chronobiology international 20060101
Headache in a patient with ulcerative colitis. Internal and emergency medicine 20060101
[Anticonvulsants treatment of psychiatric disorder in elderly patients]. Przeglad lekarski 20060101
Treatment of status epilepticus in adults: guidelines of the Italian League against Epilepsy. Epilepsia 20060101
Anticonvulsant and neurotoxicity profile of Nardostachys jatamansi in rats. Journal of ethnopharmacology 20051201
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition. The Journal of pharmacology and experimental therapeutics 20051201
Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage. Stroke 20051201
P450 2C18 catalyzes the metabolic bioactivation of phenytoin. Chemical research in toxicology 20051201
Administer single-site 30-mL intramuscular injection? Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20051201
Phenytoin induced oxidative stress in pre- and postnatal rat development - effect of vitamin E on selective biochemical variables. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201
Unusual presentation of iatrogenic phenytoin toxicity in a newborn. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20051201
Myokymia and neuromyotonia in a cat. Journal of the American Veterinary Medical Association 20051115
Recrudescence of imported falciparum malaria after quinine therapy: potential drug interaction with phenytoin. Transactions of the Royal Society of Tropical Medicine and Hygiene 20051101
CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population. Pharmacogenetics and genomics 20051101
Severe case of phenytoin-induced anticonvulsant hypersensitivity syndrome. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051101
Neuroprotection by sodium channel blockade with phenytoin in an experimental model of glaucoma. Investigative ophthalmology & visual science 20051101
How to assess phenytoin levels. Nursing 20051101
Paraneoplastic limbic encephalitis presenting as acute viral encephalitis. Journal of neuro-oncology 20051101
Mathematical representation of analyte's capacity factor in binary solvent mobile phases using the Jouyban-Acree model. Die Pharmazie 20051101
Appropriateness of intravenous loading dose of phenytoin treatment in Srinagarind Hospital. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051101
Treatment delay and the risk of prolonged status epilepticus. Neurology 20051025
Anticonvulsant therapy for status epilepticus. The Cochrane database of systematic reviews 20051019
Differential effects of antiepileptic drugs on sexual function and hormones in men with epilepsy. Neurology 20051011
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile. Archives of toxicology 20051001
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology 20051001
CYP2C-catalyzed delta9-tetrahydrocannabinol metabolism: kinetics, pharmacogenetics and interaction with phenytoin. Biochemical pharmacology 20051001
Analysis of changes in gingival contour from three-dimensional co-ordinate data in subjects with drug-induced gingival overgrowth. Journal of clinical periodontology 20051001
Effect of ultrafiltrate volume on determination of free phenytoin concentration. Therapeutic drug monitoring 20051001
Headache and seizure in a young woman postpartum. The Journal of emergency medicine 20051001
Potentiation of acetaminophen hepatotoxicity by phenytoin, leading to liver transplantation. Digestive diseases and sciences 20051001
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats. Epilepsia 20051001
Phenytoin and cognitive decline. Stroke 20051001
Pharmacological studies on mechanisms of aminophylline-induced seizures in rats. Indian journal of experimental biology 20051001
[A pharmacokinetic analysis in a patient with acute drug poisoning]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20051001
Fatal seizures due to potential herb-drug interactions with Ginkgo biloba. Journal of analytical toxicology 20051001
Neurocysticercosis an uncommon intra-cerebral infection in Malaysia. The Medical journal of Malaysia 20051001
Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies. Brain research bulletin 20050930
Status epilepticus: an evidence based guide. BMJ (Clinical research ed.) 20050924
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20050901
Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20050901
Brainstem seizure severity regulates forebrain seizure expression in the audiogenic kindling model. Epilepsia 20050901
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy. Epilepsia 20050901
Unsuspected rhabdomyolysis associated with phenytoin. International journal of clinical pharmacology and therapeutics 20050901
[Choice and administration sequence of antiepileptic agents for status epilepticus and frequent seizures in children]. No to hattatsu = Brain and development 20050901
Necrotizing lymphadenitis associated with the phenytoin-induced hypersensitivity syndrome. Southern medical journal 20050901
Antiepileptic drug use and the occurrence of pressure ulcers among bedridden institutionalized elderly patients: a retrospective chart review. The American journal of geriatric pharmacotherapy 20050901
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050823
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050823
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050823
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050823
Fit for a fracture. The Medical journal of Australia 20050815
Hyperphosphatemia due to fosphenytoin in a pediatric ESRD patient. Pediatric nephrology (Berlin, Germany) 20050801
Protection with estradiol in developmental models of apoptotic neurodegeneration. Annals of neurology 20050801
Phenytoin reverses the chronic stress-induced impairment of memory consolidation for water maze training and depression of LTP in rat hippocampal CA1 region, but does not affect motor activity. Brain research. Cognitive brain research 20050801
Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5. The Journal of toxicological sciences 20050801
Contraception in teens with medical problems. Journal of pediatric and adolescent gynecology 20050801
Daytime encopresis associated with gland mal epileptic seizures: case report. East African medical journal 20050801
Clinical features of status epilepticus in patients with HIV infection. Neurology 20050726
A potentially significant interaction between efavirenz and phenytoin: a case report and review of the literature. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050715
Simultaneous determination of phenytoin, barbital and caffeine in pharmaceuticals by absorption (zero-order) UV spectra and first-order derivative spectra--multivariate calibration methods. Journal of pharmaceutical and biomedical analysis 20050701
The interactions of phenytoin and its binding site in DI-S6 segment of Na+ channel voltage-gated peptide by NMR spectroscopy and molecular modeling study. The journal of peptide research : official journal of the American Peptide Society 20050701
EMPACT syndrome. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20050701
Anticonvulsant hypersensitivity syndrome. International journal of dermatology 20050701
Altered cytochrome p450 metabolism of calcineurin inhibitors: case report and review of the literature. Pharmacotherapy 20050701
Establishment of rat model of drug-induced gingival overgrowth induced by continuous administration of phenytoin. Journal of pharmacological sciences 20050701
Drug treatment of neonatal seizures by neonatologists and paediatric neurologists. Journal of paediatrics and child health 20050701
The effect of phenytoin on rocuronium-induced neuromuscular block in the rat phrenic nerve-hemidiaphragm preparation. Journal of neurosurgical anesthesiology 20050701
Simultaneous determination of phenytoin and dextromethorphan in urine by solid-phase extraction and HPLC-DAD. Journal of separation science 20050701
Evaluation of antiepileptic drugs in pregnancy in a Jordanian army hospital. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20050701
Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats. European journal of pharmacology 20050615
Seizures following reduction in phenytoin level after orally administered folic acid. Neurology 20050614
Analytic performance evaluation of a new turbidimetric immunoassay for phenytoin on the ADVIA 1650 analyzer: effect of phenytoin metabolite and analogue. Therapeutic drug monitoring 20050601
High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity. Progress in neuro-psychopharmacology & biological psychiatry 20050601
Medication safety in older adults: home-based practice patterns. Journal of the American Geriatrics Society 20050601
Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin. Journal of periodontology 20050601
Status epilepticus: clinical analysis of a treatment protocol based on midazolam and phenytoin. Journal of child neurology 20050601
Cross Hypersensitivity Syndrome between Phenytoin and Carbamazepine. Pharmacy world & science : PWS 20050601
Gene variants explain patient differences in antiepileptic drug responses. JAMA 20050511
Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin. Cancer chemotherapy and pharmacology 20050501
Gene variants affect response to antiepileptic drugs. The Lancet. Neurology 20050501
Controlled double-blind trial of phenytoin vs. fluoxetine in major depressive disorder. The Journal of clinical psychiatry 20050501
Seizure and elevated blood aluminum in a remelt furnace operator: connection or coincidence? The American journal of emergency medicine 20050501
An epilepsy mutation in the beta1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin. Epilepsy research 20050501
Recurrent tumefactive demyelination in a child. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050501
[Mitral prosthetic valve and presyncope]. Anales de medicina interna (Madrid, Spain : 1984) 20050501
Impact of end-product inhibition on the determination of in vitro metabolic clearance. Xenobiotica; the fate of foreign compounds in biological systems 20050501
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050426
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20050426
Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proceedings of the National Academy of Sciences of the United States of America 20050412
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. Neurology 20050412
Blockade of sodium channels by phenytoin protects ultrastructure and attenuates lipid peroxidation in experimental spinal cord injury. Acta neurochirurgica 20050401
Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus--experience in 102 adult patients. Seizure 20050401
Absence of effect of folic acid flour fortification on anticonvulsant drug levels. The American journal of medicine 20050401
Maternal antioxidant supplementation does not reduce the incidence of phenytoin-induced cleft lip and related malformations in rats. Birth defects research. Part B, Developmental and reproductive toxicology 20050401
A fragile site at 10q23 (FRA10A) in a phenytoin-exposed fetus: a case report and review of the literature. Prenatal diagnosis 20050401
Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients. Drug metabolism and pharmacokinetics 20050401
Urinary excretion of phenytoin metabolites, 5-(4'-hydroxyphenyl)-5-phenylhydantoin and its O-glucuronide in humans and analysis of genetic polymorphisms of UDP-glucuronosyltransferases. Drug metabolism and pharmacokinetics 20050401
An experimental evaluation of anticonvulsant activity of Vitex-negundo. Indian journal of physiology and pharmacology 20050401
A comparison of two methods to determine the solubility of compounds in aerosol propellants. International journal of pharmaceutics 20050323
Levetiracetam for seizures after liver transplantation. Neurology 20050322
Correlation of susceptibility to 6-aminonicotinamide and hydrocortisone-induced cleft palate. Life sciences 20050318
[Diminished antiepileptic drug serum levels during acyclovir treatment]. Medicina clinica 20050312
The effects of phenytoin and its metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin on cellular glucose transport. Life sciences 20050304
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain. Synapse (New York, N.Y.) 20050301
Phenytoin exposure is associated with functional and cognitive disability after subarachnoid hemorrhage. Stroke 20050301
Population pharmacokinetics of motexafin gadolinium in adults with brain metastases or glioblastoma multiforme. Journal of clinical pharmacology 20050301
CARs and drugs: a risky combination. Endocrinology 20050301
Effects of phenytoin on memory, cognition and brain structure in post-traumatic stress disorder: a pilot study. Journal of psychopharmacology (Oxford, England) 20050301
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study. Internal medicine journal 20050301
Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy. Biological psychiatry 20050301
Phenytoin teratogenicity: hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism. Birth defects research. Part A, Clinical and molecular teratology 20050301
Case report: Late-onset eclampsia presents as bilateral cortical blindness. American family physician 20050301
V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. British journal of pharmacology 20050301
Focal seizures as an unusual presentation of neonatal lupus erythematosus. Asian Pacific journal of allergy and immunology 20050301
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. The AAPS journal 20050301
Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy. Annals of neurology 20050201
Cisatracurium-induced neuromuscular blockade is affected by chronic phenytoin or carbamazepine treatment in neurosurgical patients. Anesthesia and analgesia 20050201
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat. Epilepsia 20050201
radiotherapy-induced ID reaction. American journal of clinical oncology 20050201
A comparison of anticonvulsants in the treatment of impulsive aggression. Experimental and clinical psychopharmacology 20050201
Letter to the neurology editor. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050201
Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids. Epilepsy research 20050201
Phenytoin hypersensitivity syndrome masquerading as fever and systemic illness of unknown origin in an HIV-infected patient. International journal of STD & AIDS 20050201
The complexity of achieving anticoagulation control in the face of warfarin-phenytoin interaction: an Asian case report. Pharmacy world & science : PWS 20050201
Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia 20050115
Cancer risk in people with epilepsy: the role of antiepileptic drugs. Brain : a journal of neurology 20050101
Congenital bilateral perisylvian syndrome with partial epilepsy. Case report with long-term follow-up. Brain & development 20050101
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. The Journal of pediatrics 20050101
Drug-induced hypersensitivity syndrome in a premature infant. Pediatric dermatology 20050101
Mechanisms of edema after gamma knife surgery for meningiomas. Report of two cases. Journal of neurosurgery 20050101
Temporary symptomatic swelling of meningiomas following gamma knife surgery. Report of two cases. Journal of neurosurgery 20050101
Phenytoin intoxication in critically ill patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20050101
Severe hyperhomocysteinaemia and 5-oxoprolinuria secondary to antiproliferative and antimicrobial drug treatment. Journal of inherited metabolic disease 20050101
Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20050101
Permanent motor activity and learning disorders induced by exposure to phenytoin during gestation and early infancy in the rat. Neurotoxicology and teratology 20050101
Estimation of population pharmacokinetic parameters of free-phenytoin in adult epileptic patients. Archives of medical research 20050101
Breakthrough Candida infections in patients receiving voriconazole. The Annals of pharmacotherapy 20050101
Neuroendocrine changes in adult female rats prenatally exposed to phenytoin. Neurotoxicology and teratology 20050101
Phenytoin may increase the efficacy of temozolomide by methylating DNA-repair enzyme, O6-methylguanine-DNA methyltransferase in patients with glioblastoma. Medical hypotheses 20050101
[Nasotracheal fiberoptic intubation under remifentanil for sedation and analgesia in a boy with a difficult airway due to giant gingival hypertrophy]. Revista espanola de anestesiologia y reanimacion 20050101
Omeprazole affects neither electroconvulsive threshold nor anticonvulsant activity of diphenylhydantoin and carbamazepine in mice. Pharmacological reports : PR 20050101
Phenytoin poisoning. Neurocritical care 20050101
RLIP76, a non-ABC transporter, and drug resistance in epilepsy. BMC neuroscience 20050101
Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex. Epilepsy research 20050101
Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin. Scandinavian journal of urology and nephrology 20050101
[Anticonvulsive pharmacotherapy may aggravate epilepsy course]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
[Management of status epilepticus]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
[Decrease of folic acid and cognitive alterations in patients with epilepsy treated with phenytoin or carbamazepine, pilot study]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101
EMPACT syndrome. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20050101
Hospital periodontal surgery. Indian journal of dental research : official publication of Indian Society for Dental Research 20050101
The effects of phenytoin on the performance of rats in a delayed match-to-place task. Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20050101
Fluorouracil-induced neurotoxicity presenting with generalized tonic-clonic seizure. The Annals of pharmacotherapy 20041201
The peroxynitrite pathway in development: phenytoin and benzo[a]pyrene embryopathies in inducible nitric oxide synthase knockout mice. Free radical biology & medicine 20041201
Hypogeusia as an adverse reaction of phenytoin. British journal of clinical pharmacology 20041201
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis. Journal of neural transmission (Vienna, Austria : 1996) 20041201
Synthesis and evaluation of in vivo activity of diphenylhydantoin basic derivatives. European journal of medicinal chemistry 20041201
Prolonged and excessive phenytoin therapy leading to a severe and partially reversible polyneuropathy. Journal of the peripheral nervous system : JPNS 20041201
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor. Biological & pharmaceutical bulletin 20041201
Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteers. Epilepsy & behavior : E&B 20041201
Seizure prophylaxis in patients with brain tumors: a meta-analysis. Mayo Clinic proceedings 20041201
Video-EEG study in an adult and a child with eyelid myoclonia with absences. Epileptic disorders : international epilepsy journal with videotape 20041201
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison. Birth defects research. Part C, Embryo today : reviews 20041201
Effects of the antiepileptics phenytoin and zonisamide on dentin formation and bone mineral density of the mandible in growing rats. Methods and findings in experimental and clinical pharmacology 20041201
Acute phenytoin intoxication: causes, symptoms, misdiagnoses, and outcomes. The Kaohsiung journal of medical sciences 20041201
Drug-induced hypersensitivity syndrome due to anticonvulsants in a two-year-old boy. The Journal of dermatology 20041201
Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20041115
Expression of growth factors in the gingival crevice fluid of patients with phenytoin-induced gingival enlargement. Archives of oral biology 20041101
Probable codeine phosphate-induced seizures. The Annals of pharmacotherapy 20041101
Longer term outcome of children born to mothers with epilepsy. Journal of neurology, neurosurgery, and psychiatry 20041101
Lack of a clinically significant effect of zonisamide on phenytoin steady-state pharmacokinetics in patients with epilepsy. Journal of clinical pharmacology 20041101
Impact of phenytoin therapy on the skin and skin disease. Expert opinion on drug safety 20041101
Treatment of posttraumatic stress disorder with phenytoin: an open-label pilot study. The Journal of clinical psychiatry 20041101
Gene expression analysis of peroxisome proliferators- and phenytoin-induced hepatotoxicity using cDNA microarray. The Journal of veterinary medical science 20041101
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose. The American journal of emergency medicine 20041101
Lower phenytoin serum levels in persons switched from brand to generic phenytoin. Neurology 20041026
[Association between genetic polymorphisms of CYP2C19 and CYP2C9 and phenytoin serum concentration]. Zhonghua yi xue za zhi 20041017
Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms. Therapeutic drug monitoring 20041001
Simple and rapid micellar electrokinetic capillary chromatographic method for simultaneous determination of four antiepileptics in human serum. Biomedical chromatography : BMC 20041001
Do vascular endothelial growth factor and basic fibroblast growth factor promote phenytoin's wound healing effect in rat? An immunohistochemical and histopathologic study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20041001
Catheter occlusion from intravenous phenytoin. Annals of emergency medicine 20041001
The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey. The British journal of general practice : the journal of the Royal College of General Practitioners 20041001
Serum albumin-adjusted phenytoin levels: an approach for predicting drug efficacy in patients with epilepsy, suitable for developing countries. International journal of clinical pharmacology and therapeutics 20041001
Nurse sued when child dies from error in interpreting drug dosage. Nursing law's Regan report 20041001
Influence of high fat diet (butter) on pharmacokinetics of phenytoin and carbamazepine. Methods and findings in experimental and clinical pharmacology 20041001
Studies of phenytoin binding to human serum albumin by high-performance affinity chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040925
Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs. European journal of pharmacology 20040919
Seizure associated with chloroquine therapy in a patient with systemic lupus erythematosus. Rheumatology international 20040901
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors. Archives of biochemistry and biophysics 20040901
Antisense evidence for nuclear factor-kappaB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress. Molecular pharmacology 20040901
Phenobarbital for the treatment of epilepsy in the 21st century: a critical review. Epilepsia 20040901
Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models. Journal of neural transmission (Vienna, Austria : 1996) 20040901
Topical phenytoin suspension and normal saline in the treatment of leprosy trophic ulcers: a randomized, double-blind, comparative study. The Journal of dermatological treatment 20040901
Total external ophthalmoplegia induced by phenytoin: a case report and review of literature. Neurology India 20040901
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil. Arquivos de neuro-psiquiatria 20040901
Intracerebral hemorrhage associated with use of an imported medication. The American journal of geriatric pharmacotherapy 20040901
The pharmacokinetics of piritramide after prolonged administration to intensive care patients. European journal of anaesthesiology 20040901
Coadministration of lopinavir/ritonavir and phenytoin results in two-way drug interaction through cytochrome P-450 induction. Journal of acquired immune deficiency syndromes (1999) 20040815
[Anticonvulsant hypersensitivity syndrome]. Orvosi hetilap 20040808
Phase I trial of vinorelbine and diphenylhydantoin in patients with refractory carcinoma. Investigational new drugs 20040801
Early histopathologic changes in purple glove syndrome. Journal of cutaneous pathology 20040801
Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI. Experimental neurology 20040801
The use of urine to clarify the genotype of a patient with toxic phenytoin concentrations who had undergone peripheral blood stem cell transplantation. British journal of clinical pharmacology 20040801
Non-invasive monitoring of phenytoin by reverse iontophoresis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040801
Phenytoin overdose complicated by prolonged intoxication and residual neurological deficits. Emergency medicine Australasia : EMA 20040801
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs. Clinical biochemistry 20040801
Proliferative response to phenytoin and nifedipine in gingival fibroblasts cultured from humans with gingival fibromatosis. Fundamental & clinical pharmacology 20040801
Charcoal hemoperfusion in an elderly man with life-threatening adverse reactions due to poor metabolism of phenytoin. Journal of the Formosan Medical Association = Taiwan yi zhi 20040801
Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment. Onkologie 20040801
Paroxysmal dysarthria and ataxia after midbrain infarction. Neurology 20040727
Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats. Neuroreport 20040719
Topical phenytoin for wound healing. Dermatology online journal 20040715
Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin. The Journal of biological chemistry 20040709
Effects of tilting and volume loading on plasma levels and urinary excretion of relaxin, NT-pro-ANP, and NT-pro-BNP in male volunteers. Journal of applied physiology (Bethesda, Md. : 1985) 20040701
Phenytoin overview--metabolite interference in some immunoassays could be clinically important. Archives of pathology & laboratory medicine 20040701
Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs. Epilepsia 20040701
Profiles in patient safety: when an error occurs. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040701
Acetaminophen misconceptions. Hepatology (Baltimore, Md.) 20040701
Prophylactic phenytoin does not improve cerebral edema or survival in acute liver failure--a controlled clinical trial. Journal of hepatology 20040701
Is there enough clinical evidence to use honey to manage wounds? Journal of wound care 20040701
Recreational use of phenytoin, marijuana, and alcohol: a case report. Neurology 20040622
Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs. Toxicology letters 20040615
Antiepileptic drug use increases rates of bone loss in older women: a prospective study. Neurology 20040608
Connective tissue metabolism and gingival overgrowth. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20040604
Loss of seizure control due to anticonvulsant-induced hypocalcemia. The Annals of pharmacotherapy 20040601
The role of seizures in reversible posterior leukoencephalopathy. Seizure 20040601
Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration. Atherosclerosis 20040601
Therapeutic doses of topiramate are not toxic to the developing rat brain. Experimental neurology 20040601
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data. Journal of clinical pharmacy and therapeutics 20040601
The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29. Molecular pharmacology 20040601
[Stevens-Johnson syndrome, toxic epidermal necrolysis and phenytoin. Factors linked to a higher risk]. Revista de neurologia 20040601
Increased depressant effect of phenytoin sodium as compared to carbamazepine on cortical excitability: a transcranial magnetic evaluation. Neurology India 20040601
Is there a role for surgery in the management of dropped head syndrome? British journal of neurosurgery 20040601
Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect. Journal of the Indian Society of Pedodontics and Preventive Dentistry 20040601
Treatment of status epilepticus in children. Pediatric annals 20040601
Positive effects of phenytoin on experimental colonic anastomoses. International journal of colorectal disease 20040501
Evaluation of the use of reporter antigens in an auricular lymph node assay to assess the immunosensitizing potential of drugs. Toxicological sciences : an official journal of the Society of Toxicology 20040501
Genetic polymorphism of cytochrome P450 2C9 in diphenylhydantoin-induced cutaneous adverse drug reactions. European journal of clinical pharmacology 20040501
Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons. Neuroscience research 20040501
Postoperative seizures after sevoflurane anesthesia in a neonate. Acta anaesthesiologica Scandinavica 20040501
Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with seizures. Annals of emergency medicine 20040501
A prisoner with acute renal failure. Lancet (London, England) 20040501
Effects of chronic stress and phenytoin on the long-term potentiation (LTP) in rat hippocampal CA1 region. Acta biochimica et biophysica Sinica 20040501
Phenytoin-induced gingival overgrowth in un-cooperated epilepsy patients. Yonsei medical journal 20040430
Characterization of the selectivity of a phenytoin imprinted polymer. Journal of chromatography. A 20040423
Characterization of drug interactions with soluble beta-cyclodextrin by high-performance affinity chromatography. Journal of chromatography. A 20040409
The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy. Medical science monitor : international medical journal of experimental and clinical research 20040401
A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury. Annals of emergency medicine 20040401
Informed consent: time for a national dialogue? Annals of emergency medicine 20040401
Studying long-term effect of phenytoin either alone or combined with ascorbic acid on the anesthetic effect of urethane in rats. Fundamental & clinical pharmacology 20040401
Block of human NaV1.5 sodium channels by novel alpha-hydroxyphenylamide analogues of phenytoin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040401
Synthesis and pharmacological evaluation of newer substituted benzoxazepine derivatives as potent anticonvulsant agents. European journal of medicinal chemistry 20040401
Facilitation of a weak training experience in the 1-day-old chick using diphenylhydantoin: a pharmacological and biochemical study. Pharmacology, biochemistry, and behavior 20040401
Management of seizures in children with falciparum malaria. Tropical doctor 20040401
Quality of life improvement with conversion to lamotrigine monotherapy. Epilepsy & behavior : E&B 20040401
Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection. Journal of child neurology 20040401
Phenytoin efficacy in treating the diabetic foot ulcer of a haemodialysis patient. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040301
Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy. Journal of the American Geriatrics Society 20040301
Treatment with the antiepileptic drugs phenytoin and gabapentin ameliorates seizure and paralysis of Drosophila bang-sensitive mutants. Journal of neurobiology 20040301
Cost-effectiveness of oral phenytoin, intravenous phenytoin, and intravenous fosphenytoin in the emergency department. Annals of emergency medicine 20040301
Fosphenytoin farewell? Annals of emergency medicine 20040301
Preventing phenytoin intoxication: safer use of a familiar anticonvulsant. The Journal of family practice 20040301
A comparison of phenytoin-loading techniques in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040301
Interaction between anticonvulsants and human placental carnitine transporter. Epilepsia 20040301
Cost of epilepsy in patients attending a secondary-level hospital in India. Epilepsia 20040301
[Clinical guidelines for treatment of epilepsy in children]. No to hattatsu = Brain and development 20040301
Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin. Southern medical journal 20040301
The conformation and movement of Na channel inactivation gate peptide in linker between domain III and IV during inactivation by NMR spectroscopy and molecular modeling study. The journal of peptide research : official journal of the American Peptide Society 20040301
Satoyoshi syndrome. Neurology India 20040301
Modulation of antiepileptic effect of phenytoin and carbamazepine by melatonin in mice. Methods and findings in experimental and clinical pharmacology 20040301
Influence of chronic phenytoin administration on the pharmacokinetics and pharmacodynamics of vecuronium. Anesthesiology 20040301
Effect of melatonin on neurobehavioral dysfunctions induced by intrauterine hypoxia in rats. Central European journal of public health 20040301
Effect of melatonin on biochemical variables induced by phenytoin in organs of mothers, foetuses and offsprings of rats. Central European journal of public health 20040301
Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. Central European journal of public health 20040301
The effects of phenytoin and phenobarbital on seizures induced by imipenem/cilastatin in rats. Acta neurologica Belgica 20040301
Role of phenytoin in wound healing: microarray analysis of early transcriptional responses in human dermal fibroblasts. Biochemical and biophysical research communications 20040213
Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy. British journal of cancer 20040209
Highly accurate nephelometric titrimetry. Journal of pharmaceutical sciences 20040201
Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium. Journal of neurology, neurosurgery, and psychiatry 20040201
L-histidine is a beneficial adjuvant for antiepileptic drugs against maximal electroshock-induced seizures in mice. Amino acids 20040201
Corticosteroids, central serous chorioretinopathy, and neurocysticercosis. Archives of ophthalmology (Chicago, Ill. : 1960) 20040201
Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider. Journal of neuro-oncology 20040201
Effects of fosphenytoin on nerve agent-induced status epilepticus. Drug and chemical toxicology 20040201
Phenytoin penetration into chronic subdural haematomas. British journal of neurosurgery 20040201
Trigeminal neuralgia and glossopharyngeal neuralgia. Neurologic clinics 20040201
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7. Molecular and cellular endocrinology 20040115
Severe intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction. Neurology 20040113
Severe intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction. Neurology 20040113
CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects. Life sciences 20040102
Aplastic anemia complicating systemic lupus erythematosus: successful management with cyclosporine. Rheumatology international 20040101
Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature. International journal of dermatology 20040101
Spotlight on oxcarbazepine in epilepsy. CNS drugs 20040101
Use of phenytoin in pregnancy for epileptic seizure prevention: a case report. Journal of midwifery & women's health 20040101
[Cross-hypersensitivity syndrome between antiepileptic drugs: report of a case]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101
Self-selection and use patterns of over-the-counter omeprazole for frequent heartburn. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040101
Phenytoin-induced lymphocytic chemotaxis, angiogenesis and accelerated healing of decubitus ulcer in a patient with stroke. The Journal of international medical research 20040101
Phenytoin sodium as a treatment for ventricular dysrhythmia in horses. Journal of veterinary internal medicine 20040101
Newer anticonvulsants in the treatment of bipolar disorder. The Journal of clinical psychiatry 20040101
Influence of aging on serum phenytoin concentrations: a pharmacokinetic analysis based on therapeutic drug monitoring data. Epilepsy research 20040101
[Nonconvulsion epileptic encepholopathies and their treatment]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
Cerebral venous sinus thrombosis as presenting feature of Crohn's disease. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20040101
DRESS syndrome associated with carbamazepine and phenytoin. European journal of dermatology : EJD 20040101
[Antihyperalgesic activity of chlorimipramine and sodium phenytoin in an induced model of neuropathic pain in rats]. Cirugia y cirujanos 20040101
Significance of MDR1 and multiple drug resistance in refractory human epileptic brain. BMC medicine 20040101
Paradoxical cerebral cortical hyperexcitability following flupirtine overdose. Journal of toxicology. Clinical toxicology 20040101
Neuroleptic malignant syndrome in a child treated with an atypical antipsychotic. Journal of toxicology. Clinical toxicology 20040101
Classical Michaelis-Menten and system theory approach to modeling metabolite formation kinetics. European journal of drug metabolism and pharmacokinetics 20040101
Therapeutic drug monitoring of old and newer anti-epileptic drugs. Clinical chemistry and laboratory medicine 20040101
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693]. BMC dermatology 20040101
Management issues of neuropathic trigeminal pain from a medical perspective. Journal of orofacial pain 20040101
A junctional rhythm with retrograde conduction and bradycardia as a dysrhythmia caused by oral phenytoin toxicity. Boletin de la Asociacion Medica de Puerto Rico 20040101
Influence of LY 300164 alone or in combination with carbamazepine or diphenylhydantoin on the body temperature in mice. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101
Discrete and contextual cue alterations eliminate the instrumental appetitive-to-aversive transfer impairment in phenytoin-treated rats. Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20040101
The antiepileptic drug diphenylhydantoin affects the structure of the human erythrocyte membrane. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Phenytoin. Report on carcinogens : carcinogen profiles 20040101
Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole. Toxicology letters 20031210
Subthreshold oscillations generated by TTX-sensitive sodium currents in dorsal cochlear nucleus pyramidal cells. Experimental brain research 20031201
Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration. British journal of clinical pharmacology 20031201
Phenytoin overview--metabolite interference in some immunoassays could be clinically important: results of a College of American Pathologists study. Archives of pathology & laboratory medicine 20031201
Diffusion tensor MRI and fiber tractography of cerebellar atrophy in phenytoin users. Epilepsia 20031201
Prophylactic effect of phenytoin in bipolar disorder: a controlled study. Bipolar disorders 20031201
Influence of coadministered antiepileptic drugs on serum zonisamide concentrations in epileptic patients: quantitative analysis based on suitable transforming factor. Biological & pharmaceutical bulletin 20031201
Acute psychosis due to treatment with phenytoin in a nonepileptic patient. Epilepsy & behavior : E&B 20031201
Postictal laughter following absence status epilepticus. Epilepsy & behavior : E&B 20031201
Phenytoin and carbamazepine cross reactivity: report of a case and review of literature. Postgraduate medical journal 20031201
Noncompliance leading to drug accumulation resulting in phenytoin toxicity. Journal of the National Medical Association 20031201
Jiedu tongbi tang plus phenytoin sodium for severe acute sciatica. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20031201
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Multiple congenital anomalies associated with in utero exposure of phenytoin: possible hypoxic ischemic mechanism? Birth defects research. Part A, Clinical and molecular teratology 20031201
Motor disturbances in mice with deficiency of the sodium channel gene Scn8a show features of human dystonia. Experimental neurology 20031201
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Effect of sodium diphenylhydantoin on skin wound healing in rats. Plastic and reconstructive surgery 20031101
Phenytoin-induced linear IgA dermatosis mimicking toxic epidermal necrolysis. The Australasian journal of dermatology 20031101
Voltage-gated sodium channel blockers as cytostatic inhibitors of the androgen-independent prostate cancer cell line PC-3. Molecular cancer therapeutics 20031101
[Clinical significance of correcting the serum level of phenytoin according to the albuminaemia in hospitalized patients and outpatients]. Revista de neurologia 20031101
Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region. Epilepsia 20031101
Phenytoin and phenobarbital stable isotope studies in neonates. Pediatric neurology 20031101
Anticonvulsant potential of holy basil, Ocimum sanctum Linn., and its cultures. Indian journal of experimental biology 20031101
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The subgingival microflora in phenytoin-induced gingival hyperplasia. Journal of periodontal research 20031001
ECG features of sodium channel blockade in rodent phenytoin toxicity and effect of hypertonic saline. Veterinary and human toxicology 20031001
Indigent breast cancer patients among all racial and ethnic groups present with more advanced disease compared with nationally reported data. American journal of surgery 20031001
The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction. Pharmaceutical research 20031001
Rapid i.v. loading with phenytoin with subsequent dose adaptation using non-steady-state serum levels and a Bayesian forecasting computer program to predict maintenance doses. Journal of clinical pharmacy and therapeutics 20031001
Recovery of phenytoin from feeding formulas and protein mixtures. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030915
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[Calculating how long phenytoin intoxication lasts]. Revista de neurologia 20030901
Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): three case reports. British journal of cancer 20030818
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Oxidative stress-induced homologous recombination as a novel mechanism for phenytoin-initiated toxicity. The Journal of pharmacology and experimental therapeutics 20030801
Fulfenamic acid sensitive, Ca(2+)-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons. Neuroscience research 20030801
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[Variance of bioavailability of pharmaceutical preparations and analysis of factors affecting it]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030701
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Modulation of androgen metabolism by phenytoin, oestradiol and tamoxifen in human gingival fibroblasts. Journal of clinical periodontology 20030601
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Synthesis, structure and antiarrhythmic properties evaluation of new basic derivatives of 5,5-diphenylhydantoin. European journal of medicinal chemistry 20030601
Emerging challenges in cervical lymphadenopathy. Hospital medicine (London, England : 1998) 20030601
Influence of honey on the pharmacokinetics of phenytoin in healthy rabbits. Methods and findings in experimental and clinical pharmacology 20030601
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Effects of menatetrenone on the bone and serum levels of vitamin K2 (menaquinone derivatives) in osteopenia induced by phenytoin in growing rats. Nutrition (Burbank, Los Angeles County, Calif.) 20030501
Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods. Farmaco (Societa chimica italiana : 1989) 20030501
Effects of phenytoin on morphology and structure of hippocampal CA3 pyramidal neurons of rats in chronic stress. Acta pharmacologica Sinica 20030501
Prophylactic anticonvulsants in patients with brain tumour. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20030501
Semisolid matrix filled capsules: an approach to improve dissolution stability of phenytoin sodium formulation. Drug development and industrial pharmacy 20030501
The management of idiopathic olfactory hallucinations: a study of two patients. The Laryngoscope 20030501
Neuropathic cranial pain. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20030501
Severe intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction. Neurology 20030422
Neonatal seizures and their treatment. Current opinion in neurology 20030401
Therapeutic monitoring of digoxin and antiepileptic drugs in Egypt and Saudi Arabia. Therapeutic drug monitoring 20030401
A randomized, crossover, assessor-blind study of the bioequivalence of a single oral dose of 200 mg of four formulations of phenytoin sodium in healthy, normal Indian volunteers. Therapeutic drug monitoring 20030401
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Involvement of glutamate neurotransmission in the development of excessive wheel running in Lewis rats. Neurochemical research 20030401
Valproate overdose: a comparative cohort study of self poisonings. British journal of clinical pharmacology 20030401
New management strategies in the treatment of status epilepticus. Mayo Clinic proceedings 20030401
Ionic currents underlying rhythmic bursting of ventral mossy cells in the developing mouse dentate gyrus. The European journal of neuroscience 20030401
Intravenous fosphenytoin in acute mania. The Journal of clinical psychiatry 20030401
Epilepsy and pregnancy: maternal and fetal effects of phenytoin. Critical care nurse 20030401
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Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use. Pediatric neurology 20030401
A simple and sensitive HPLC method for determination of gliclazide in human serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305
Expressive aprosody and amusia as a manifestation of right hemisphere seizures. Epilepsia 20030301
The effects of folic acid in the prevention of neural tube development defects caused by phenytoin in early chick embryos. Spine 20030301
Evaluation of therapeutic drug monitoring of antiepileptic drugs. International journal of clinical pharmacology and therapeutics 20030301
The protective effect of Allium sativum L. clove aqueous and methanolic extracts against hypoxia-induced lethality in mice. Phytotherapy research : PTR 20030301
Effects of valproate, phenytoin, and zonisamide on clonic and tonic seizures induced by acute and repeated exposure of mice to flurothyl. Physiology & behavior 20030301
Effects of medicinal compounds on the differentiation of the eukaryotic microorganism dictyostelium discoideum: can this model be used as a screening test for reproductive toxicity in humans? Die Pharmazie 20030301
[Epileptic Münchausen syndrome by idiosyncratic of effect antiepileptic drugs]. Revue neurologique 20030301
Anticonvulsant action of celecoxib (alone and in combination with sub-threshold dose of phenytoin) in electroshock induced convulsion. Methods and findings in experimental and clinical pharmacology 20030301
Topical phenytoin versus EUSOL in the treatment of non-malignant chronic leg ulcers. East African medical journal 20030301
Status epilepticus: emergency management. Indian journal of pediatrics 20030301
[Brain irradiation and phenytoin: a dangerous liaison?]. Praxis 20030226
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Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity. Epilepsy & behavior : E&B 20030201
Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapy. Orthodontics & craniofacial research 20030201
Phenytoin-induced toxic cholestatic hepatitis in a patient with skin lesions: case report. Southern medical journal 20030201
[Population pharmacokinetics of phenytoin in pediatric patients]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030201
Practice parameter: antiepileptic drug prophylaxis in severe traumatic brain injury: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 20030114
Crystal modification of phenytoin using different solvents and crystallization conditions. International journal of pharmaceutics 20030102
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation. Neuroscience letters 20030102
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. The Cochrane database of systematic reviews 20030101
Fosphenytoin: clinical pharmacokinetics and comparative advantages in the acute treatment of seizures. Clinical pharmacokinetics 20030101
Truncus arteriosus in fetal hydantoin syndrome - a new association? Indian pediatrics 20030101
[Acute cerebellar atrophy caused by diphenylhydantoin intoxication resulting from drug interaction]. Revista de neurologia 20030101
Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain. Neuroscience 20030101
Depression of phenytoin metabolic capacity by 5-fluorouracil and doxifluridine in rats. The Journal of pharmacy and pharmacology 20030101
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[Drug safety. Preventing medication errors]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101
An assessment of the in vitro antimicrobial effects of two antiepileptic drugs--sodium valproate and phenytoin. Antonie van Leeuwenhoek 20030101
Synthesis of newer indolyl/phenothiazinyl substituted 2-oxo/thiobarbituric acid derivatives as potent anticonvulsant agents. Arzneimittel-Forschung 20030101
Hypothermia and phenytoin toxicity. Clinical neuropharmacology 20030101
Simultaneous plasma lamotrigine analysis with carbamazepine, carbamazepine 10,11 epoxide, primidone, phenytoin, phenobarbital, and PEMA by micellar electrokinetic capillary chromatography (MECC). Journal of analytical toxicology 20030101
A static magnetic field modulates severity of audiogenic seizures and anticonvulsant effects of phenytoin in DBA/2 mice. Epilepsy research 20030101
Phenytoin and phenobarbital inhibit human HERG potassium channels. Epilepsy research 20030101
[On the possibility of the correction of emotional disorders under the conditions of the action of a destabilizing factor]. Fiziologiia cheloveka 20030101
Impulsive versus premeditated aggression: implications for mens rea decisions. Behavioral sciences & the law 20030101
Some antiepileptic compounds impair learning by rats in a Morris water maze. Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20030101
Magnesium sulphate versus phenytoin for eclampsia. The Cochrane database of systematic reviews 20030101
Effect of prenatal phenytoin administration on the fine structure of rat myocardium and aorta. Pathology, research and practice 20030101
Validated high performance liquid chromatographic method for simultaneous determination of phenytoin, phenobarbital and carbamazepine in human serum. Arzneimittel-Forschung 20030101
Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy. Polish journal of pharmacology 20030101
Nicotine diminishes anticonvulsant activity of antiepileptic drugs in mice. Polish journal of pharmacology 20030101
Drug-induced gingival overgrowth. Journal of the Massachusetts Dental Society 20030101
[Phenytoin: paradoxical toxicity; a discussion of 4 cases]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101
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Therapeutic drug monitoring on COBAS INTEGRA 400: reply to Hermida, et al. in Therapeutic drug monitoring 2001;23:725-727. Therapeutic drug monitoring 20021201
Comment: phenytoin/isradipine interaction causing severe neurologic toxicity. The Annals of pharmacotherapy 20021201
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19. Epilepsy research 20021201
Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration. British journal of clinical pharmacology 20021201
Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin. Neurological research 20021201
Low-affinity kainate receptor-mediated events reduce the protective activity of phenobarbital and diphenylhydantoin against maximal electroshock in mice. Neuropharmacology 20021201
Eight-year study of childhood status epilepticus: midazolam infusion in management and outcome. Journal of child neurology 20021201
Therapy with hypertonic saline in combination with anti-convulsants for hyponatremia-induced seizure: a case report and review of the literature. Hawaii medical journal 20021201
Role of pharmacologic enhancement of p-450 in cyclosporine overdose. Transplantation 20021115
Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 20021101
Neurotoxic damage of granule cells in the dentate gyrus and the cerebellum and cognitive deficit following neonatal administration of phenytoin in mice. Journal of neuropathology and experimental neurology 20021101
Administration of phenytoin and cytomegalovirus infection in the terminal ileum. Journal of gastroenterology and hepatology 20021101
Evidence for Ras-dependent signal transduction in phenytoin teratogenicity. Toxicology and applied pharmacology 20021101
Paroxysmal dyskinesia in phenytoin toxicity. The Journal of the Association of Physicians of India 20021101
New antiepileptic drug therapies. Neurologic clinics 20021101
Developmental changes in the liver weight- and body weight-normalized clearance of theophylline, phenytoin and cyclosporine in children. International journal of clinical pharmacology and therapeutics 20021101
Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. Neuroreport 20021028
Teratogen-induced limb defects. American journal of medical genetics 20021015
Inhibitory effects of tricyclic antidepressants (TCAs) on human cytochrome P450 enzymes in vitro: mechanism of drug interaction between TCAs and phenytoin. Drug metabolism and disposition: the biological fate of chemicals 20021001
Therapeutic drug monitoring of anticonvulsant drugs by micellar HPLC with direct injection of serum samples. Clinical chemistry 20021001
Vecuronium sensitivity in part due to acute use of phenytoin. Anesthesiology 20021001
[A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs]. Revista de neurologia 20021001
[Periodic lateralised epileptiform discharges as a form of presentation of neurosyphilis]. Revista de neurologia 20021001
A case of hypersensitivity syndrome due to phenytoin. The Journal of dermatology 20021001
Phenytoin-mediated androgen metabolism in gingival fibroblasts. Effects of the antiandrogen finasteride and the alkaline phosphatase inhibitor levamisole. Journal of clinical periodontology 20021001
Microdialysis sampling of carbamazepine, phenytoin and phenobarbital in subcutaneous extracellular fluid and subdural cerebrospinal fluid in humans: an in vitro and in vivo study of adsorption to the sampling device. Pharmacology & toxicology 20021001
Lack of effects of prolonged treatment with phenobarbital or phenytoin on the expression of P-glycoprotein in various rat brain regions. European journal of pharmacology 20020913
Use of anticonvulsants for treatment of neuropathic pain. Neurology 20020910
Adverse effects of phenytoin given for late-onset seizures in adults with Down syndrome. Neurology 20020910
Hypoglycaemia induced by phenytoin treatment for partial status epilepticus. Journal of neurology, neurosurgery, and psychiatry 20020901
Phenytoin/isradipine interaction causing severe neurologic toxicity. The Annals of pharmacotherapy 20020901
Effects on toes from prenatal exposure to anticonvulsants. Teratology 20020901
Evaluation of potential losartan-phenytoin drug interactions in healthy volunteers. Clinical pharmacology and therapeutics 20020901
Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects. European journal of clinical pharmacology 20020901
Rationalization of an antiepileptic drug formulation. Indian pediatrics 20020901
Subacute cutaneous lupus erythematosus associated with phenytoin. Clinical and experimental dermatology 20020901
Dilantin as anticonvulsant in eclampsia. Journal of the Indian Medical Association 20020901
A case of phenytoin hypersensitivity syndrome. Journal of drugs in dermatology : JDD 20020901
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Phenytoin toxicity as a result of 5-fluorouracil administration. The New Zealand medical journal 20020809
Postpartum eclampsia. American family physician 20020801
Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report. Oncology (Williston Park, N.Y.) 20020801
Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy research 20020801
Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. Prenatal diagnosis 20020801
Effect of seizures and antiepileptic drugs on prolactin secretions. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020801
Dexamethasone/phenytoin interactions: neurooncological concerns. Swiss medical weekly 20020727
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Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer. American journal of clinical pathology 20020701
Effect of prenatal exposure to anticonvulsant drugs on dermal ridge patterns of fingers. Teratology 20020701
Effects of classical antiepileptics on thresholds for phenomena induced by cortical stimulation in rats. The Journal of pharmacy and pharmacology 20020701
Toxic epidermal necrolysis after phenytoin usage in a brain trauma patient. Journal of neurosurgical anesthesiology 20020701
An involvement of granulocyte medullasin in phenytoin-induced gingival overgrowth in rats. Japanese journal of pharmacology 20020701
Modeling and kinetic analysis of the reaction system using whole cells with separately and co-expressed D-hydantoinase and N-carbamoylase. Biotechnology and bioengineering 20020630
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Identification of catalase in human livers as a factor that enhances phenytoin dihydroxy metabolite formation by human liver microsomes. Biochemical pharmacology 20020615
Prediction of compound signature using high density gene expression profiling. Toxicological sciences : an official journal of the Society of Toxicology 20020601
Effect of albumin on phenytoin and tolbutamide metabolism in human liver microsomes: an impact more than protein binding. Drug metabolism and disposition: the biological fate of chemicals 20020601
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs. Therapeutic drug monitoring 20020601
Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis. Therapeutic drug monitoring 20020601
Interpatient and intrapatient variability in phenytoin protein binding. Therapeutic drug monitoring 20020601
How high can we go with phenytoin? Therapeutic drug monitoring 20020601
Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum. Therapeutic drug monitoring 20020601
Postictal mixed transcortical aphasia. Seizure 20020601
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy. Diabetes care 20020601
Task-related EEG and ERP changes without performance impairment following a single dose of phenytoin. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20020601
Paraquat detoxicative system in the mouse liver postmitochondrial fraction. Archives of biochemistry and biophysics 20020601
Hypocalcemia-like electrocardiographic changes after administration of intravenous fosphenytoin. Mayo Clinic proceedings 20020601
Human herpesvirus 6 encephalitis associated with hypersensitivity syndrome. Annals of neurology 20020601
Phenytoin blocks retinal ganglion cell death after partial optic nerve crush. Experimental eye research 20020601
Acute symptomatic seizures due to single CT lesions: how long to treat with antiepileptic drugs? Neurology India 20020601
Incidence of phenytoin induced gingival overgrowth in epileptic children: a six month evaluation. Journal of the Indian Society of Pedodontics and Preventive Dentistry 20020601
Falsely positive dexamethasone suppression test in a patient treated with phenytoin to prevent seizures due to nocardia brain abscesses. Swiss medical weekly 20020518
Polarographic determination of phenytoin and benzophenone (as impurity) in pharmaceutical preparations. Journal of pharmaceutical and biomedical analysis 20020515
Probable metabolic interaction of doxifluridine with phenytoin. The Annals of pharmacotherapy 20020501
Ophthalmic findings in fetal anticonvulsant syndrome(s). Ophthalmology 20020501
Phenytoin assay errors in uremia. The Annals of pharmacotherapy 20020501
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? Epilepsia 20020501
Seizure reduction and quality of life improvements in people with epilepsy. Epilepsia 20020501
[An increase in serum phenytoin concentration by changes of dosage form: case reports and its mechanism]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020501
Time course of lamotrigine de-induction: impact of step-wise withdrawal of carbamazepine or phenytoin. Epilepsy research 20020501
[Possible gabapentin phenytoin interaction]. Revista de neurologia 20020501
Neonatal mydriasis: intravenous lidocaine adverse reaction. Journal of child neurology 20020501
[Pneumoencephaly and convulsive crises after inadvertent dural puncture in an obstetric patient]. Revista espanola de anestesiologia y reanimacion 20020501
Selective requirement for CD40-CD154 in drug-induced type 1 versus type 2 responses to trinitrophenyl-ovalbumin. Journal of immunology (Baltimore, Md. : 1950) 20020415
Prospective study of local cutaneous reactions in patients receiving IV phenytoin. Neurology 20020409
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data. Pharmacogenetics 20020401
Myotonic dystrophy type 1 (DM1) presenting with laryngeal stridor and vocal fold paresis. Muscle & nerve 20020401
Comment: unbound drug concentration versus unbound drug fraction. The Annals of pharmacotherapy 20020401
Fatal case of accidental intra-arterial phenytoin injection. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20020401
Is retrograde perfusion necessary for spinal cord protection? The Annals of thoracic surgery 20020401
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD. Journal of chromatographic science 20020401
Effect of some antiepileptic drugs on brain histaminergic systems in the rat. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401
Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizures. Phytomedicine : international journal of phytotherapy and phytopharmacology 20020401
Posterior leukoencephalopathy following cisplatin, bleomycin and vinblastine therapy for germ cell tumor of the ovary. The journal of obstetrics and gynaecology research 20020401
Effect of melatonin and phenytoin on an intracortical ferric chloride model of posttraumatic seizures in rats. Methods and findings in experimental and clinical pharmacology 20020401
Extravasation injury of the upper extremity by intravenous phenytoin. Anesthesia and analgesia 20020301
Emergency department drug therapy for status epilepticus in adults. Emergency medicine journal : EMJ 20020301
Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes. European journal of pharmacology 20020301
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis. Electrophoresis 20020301
Pharmacology advances in the neuroscience intensive care unit. Critical care nursing clinics of North America 20020301
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Effect of food on absorption of Dilantin Kapseals and Mylan extended phenytoin sodium capsules. Neurology 20020226
Effects of phenytoin and/or vitamin K2 (menatetrenone) on bone mineral density in the tibiae of growing rats. Life sciences 20020215
Phenobarbital and MK-801, but not phenytoin, improve the long-term outcome of status epilepticus. Annals of neurology 20020201
Pharmacist impact on posttraumatic seizure prophylaxis in patients with head injury. Pharmacotherapy 20020201
Altered irinotecan metabolism in a patient receiving phenytoin. Anti-cancer drugs 20020201
Add-on phenytoin fails to prevent early seizures after surgery for supratentorial brain tumors: a randomized controlled study. Epilepsia 20020201
The intracerebral administration of phenytoin using controlled-release polymers reduces experimental seizures in rats. Epilepsy research 20020201
Significant reduction of sertraline plasma levels by carbamazepine and phenytoin. European journal of clinical pharmacology 20020201
Influence of phenytoin on the disposition of irinotecan: a case report. Journal of pediatric hematology/oncology 20020201
Aplastic anemia induced by phenytoin: a geriatric case with severe folic acid deficiency. Journal of the American Geriatrics Society 20020201
[Phenytoin poisoning caused by interaction with ticlopidine]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020130
A comparison of extracellular levels of phenytoin in amygdala and hippocampus of kindled and non-kindled rats. Neuroreport 20020121
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Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia. Journal of periodontology 19970101
Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. Archives of toxicology 19970101
Postural myoclonus induced by phenytoin. Clinical neuropharmacology 19961201
Interleukin-1 beta and phenytoin reduce alpha 1 (I) procollagen mRNA expression in human gingival fibroblasts. Journal of periodontal research 19961101
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. The International journal of neuroscience 19961101
[A case of myasthenia gravis associated with long-term phenytoin therapy]. Rinsho shinkeigaku = Clinical neurology 19961101
Phenytoin-related chorea in children with deep hemispheric vascular malformations. Journal of child neurology 19961101
Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds. Epilepsia 19961001
Phenytoin-induced cerebral thrombosis in rats: cerebral ultrastructure, water content and ischaemic volume in the acute phase. International journal of experimental pathology 19961001
Phenytoin pretreatment prevents hypoxic-ischemic brain damage in neonatal rats. Brain research. Developmental brain research 19960902
[Intractable hiccup in two severely handicapped patients during phenytoin therapy]. No to hattatsu = Brain and development 19960901
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proceedings of the National Academy of Sciences of the United States of America 19960820
Association of intravenous phenytoin toxicity with demographic, clinical, and dosing parameters. The American journal of emergency medicine 19960701
Pharmacology and pharmacokinetics of fosphenytoin. Neurology 19960601
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome. Acta paediatrica (Oslo, Norway : 1992) 19960601
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus. Methods and findings in experimental and clinical pharmacology 19960601
Drug interaction between risperidone and phenytoin resulting in extrapyramidal symptoms. The Journal of clinical psychiatry 19960401
Lethal hypersensitivity myocarditis associated with the use of intravenous gammaglobulin for Guillain-Barré syndrome, in combination with phenytoin. Journal of neurology 19960401
Porphyria cutanea tarda in a patient on chronic ambulatory peritoneal dialysis. Journal of the American Society of Nephrology : JASN 19960301
[Multiple myeloma associated with phenytoin (diphenylhydantoin) therapy]. [Rinsho ketsueki] The Japanese journal of clinical hematology 19960301
Studies of Qingyangshen (II): modulatory effect of co-treatment with qingyangshen and diphenylhydantoin sodium on rat hippocampal c-fos expression during seizures. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 19960301
Intracerebroventricular pertussis toxin enhances sensitivity to chemical convulsants and decreases the protective efficacy of carbamazepine in mice. Pharmacological research 19960301
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Molecular pharmacology 19960201
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice. Journal of pharmacological and toxicological methods 19960201
Phenytoin-associated vasculitis and ANCA positivity: a case report. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19960201
Phenytoin-induced pseudolymphoma: reevaluation using modern molecular biology techniques. Epilepsia 19960101
Phenytoin-induced focal chorea. Movement disorders : official journal of the Movement Disorder Society 19960101
Magnetic resonance volumetry of the cerebellum in epileptic patients after phenytoin overdosages. European neurology 19960101
Phenytoin embryopathy: effect of epoxide hydrolase inhibitor on phenytoin exposure in utero in C57BL/6J mice. Biochemical and molecular medicine 19951201
Induction of cerebral thrombosis with phenytoin in rats. Stroke 19951101
[Toxic cholestatic hepatitis due to phenytoin]. Gastroenterologia y hepatologia 19951101
Urinary retention related to phenytoin therapy. Clinical pediatrics 19950701
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine. Journal of immunology (Baltimore, Md. : 1950) 19950701
Neuronal loss from the subthalamic nuclei in a patient with progressive chorea. Movement disorders : official journal of the Movement Disorder Society 19950501
Toxic myocardial damage due to intravenous phenytoin administration. Histopathology 19950501
Complete atrioventricular block with ventricular asystole following infusion of intravenous phenytoin. Journal of electrocardiology 19950401
Anticonvulsants suppress c-Fos protein expression in spinal cord neurons following noxious thermal stimulation. Experimental neurology 19950401
[Disorders of color perception and increase glare sensitivity in phenytoin and carbamazepine therapy. Ocular side effects of anticonvulsants]. Der Nervenarzt 19950201
MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 19950101
Clinical physiological study of the therapeutic effects of phenytoin in acute alcohol withdrawal and the asthenic-autonomic syndrome in patients with chronic alcoholism. Alcohol (Fayetteville, N.Y.) 19950101
[Persistent cerebellar ataxia after toxic administration of diphenylhydantoin]. Arquivos de neuro-psiquiatria 19941201
Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities. Journal of intellectual disability research : JIDR 19941201
Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine. Clinical pediatrics 19941001
Cognitive side-effects of phenytoin compared with carbamazepine in patients with localization-related epilepsy. Epilepsy research 19940901
Dilantin toxicity presenting as mutism following severe head injury: case report. Military medicine 19940701
Symptomatic junctional bradycardia due to lithium intoxication in patient with previously normal electrocardiogram. Lancet (London, England) 19940528
Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity. Anesthesiology 19940501
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. JAMA 19940309
Bupivacaine-induced cardiac toxicity in neonates: successful treatment with intravenous phenytoin. Anesthesiology 19940301
Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice. Clinical neuropharmacology 19940201
Effects of phenytoin and carbamazepine on cognitive functions in newly diagnosed epileptic patients. Acta neurologica Scandinavica 19940201
Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model. Reproductive toxicology (Elmsford, N.Y.) 19940101
Basilar invagination and mid-line skeletal abnormalities due to in utero exposure to phenytoin. British journal of neurosurgery 19940101
Venous irritation related to intravenous administration of phenytoin versus fosphenytoin. Pharmacotherapy 19940101
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. Biochemical pharmacology 19931214
Increased expression of type VI collagen genes in drug-induced gingival enlargement. FEBS letters 19931108
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction. Carcinogenesis 19931101
Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis. Scandinavian journal of gastroenterology 19930801
Comparative carcinogenicity of 5,5-diphenylhydantoin with or without perinatal exposure in rats and mice. Fundamental and applied toxicology : official journal of the Society of Toxicology 19930801
Disabling tremor after lamotrigine with sodium valproate. Lancet (London, England) 19930717
Hydantoin syndrome with holoprosencephaly: a possible rare teratogenic effect. Teratology 19930701
Phenytoin prophylaxis in severe pre-eclampsia and eclampsia. British journal of obstetrics and gynaecology 19930701
Valproate-induced coma: case report and literature review. The Annals of pharmacotherapy 19930501
Phenytoin-induced chronic hepatitis. Digestive diseases and sciences 19930401
Carbamazepine offers no psychotropic advantage over phenytoin in adult epileptic subjects. Seizure 19930301
Phenytoin increases gene expression for platelet-derived growth factor B chain in macrophages and monocytes. Journal of periodontology 19930301
Neuropsychiatric toxicity of phenytoin. Importance of monitoring phenytoin levels. Clinical pediatrics 19930201
Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin or sodium valproate: a random trial. Developmental medicine and child neurology 19930201
Investigation of the involvement of opioid receptors in the action of anticonvulsants. Psychopharmacology 19930101
Phenytoin toxic encephalopathy. Indian pediatrics 19930101
Phenytoin and dyskinesias: a report of two cases and review of the literature. Movement disorders : official journal of the Movement Disorder Society 19930101
Severe phenytoin hypersensitivity with myopathy: a case report. Neurology 19921201
Grand mal seizures associated with high-dose intravenous morphine infusions: incidence and possible etiology. Pain 19921101
Recessive dystrophic epidermolysis bullosa treated with phenytoin. International journal of dermatology 19921001
Phenytoin-induced pseudolymphoma. A report of a case and review of the literature. The British journal of dermatology 19921001
A study of nerve conduction velocity in patients on diphenylhydantoin therapy. The Journal of the Association of Physicians of India 19920901
Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma. Acta neurologica Scandinavica 19920901
Phenytoin reduces suxamethonium-induced myalgia. Anaesthesia 19920801
Effects of some GABAergic agents on quinine-induced seizures in mice. Experientia 19920715
[Long-term phenytoin (Diphedan) therapy leading to IgA nephropathy]. Orvosi hetilap 19920628
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. Brain research. Developmental brain research 19920619
[Encephalopathy caused by phenytoin]. Medicina clinica 19920502
Toxic reaction following the combined administration of fluoxetine and phenytoin: two case reports. Journal of neurology, neurosurgery, and psychiatry 19920501
Neuroblastoma and fetal exposure to phenytoin in a child without dysmorphic features. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19920501
Antiepileptic drug-induced lymphoproliferative disorder associated with acquired C1 esterase inhibitor deficiency and angioedema. European journal of haematology 19920501
The in vitro enzymic labilities of chemically distinct phosphomonoester prodrugs. Pharmaceutical research 19920401
Control of depression with fluoxetine and antiseizure medication in a brain-injured patient. The American journal of psychiatry 19920201
Suppression of experimental barbiturate and phenytoin withdrawal syndrome using valproate sodium. Folia medica 19920101
Cognitive effects of antiepileptic drug discontinuation. Epilepsia 19920101
Acute intermittent porphyria and epilepsy: safety of clonazepam. Epilepsia 19920101
Phenytoin toxicity in a patient with isoniazid-induced hepatitis. Tubercle 19911201
[Chronic encephalopathy induced by phenytoin]. Medicina clinica 19911109
Felbamate for partial seizures: results of a controlled clinical trial. Neurology 19911101
Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. The Journal of pharmacology and experimental therapeutics 19910801
Steroid-induced weakness in patients with primary brain tumors. Neurology 19910801
Encephalomyelopathy as an idiosyncratic reaction to carbamazepine: a case report. Neurology 19910501
Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9. Biochemical and biophysical research communications 19910329
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital]. Rinsho shinkeigaku = Clinical neurology 19910301
Mononucleosis and hepatic failure associated with diphenylhydantoin treatment in an infant. Journal of the Formosan Medical Association = Taiwan yi zhi 19910201
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia. European journal of pharmacology 19910110
Restriction fragment length polymorphisms, glucocorticoid receptors, and phenytoin-induced cleft palate in congenic strains of mice with steroid susceptibility differences. Journal of craniofacial genetics and developmental biology 19910101
Photosensitive complex partial seizures aggravated by phenytoin. Pediatric neurology 19910101
Myotonia congenita (Thomsen's disease) report of five cases in a family. Paediatrica Indonesiana 19910101
Fatal phenytoin warfarin interaction. Postgraduate medical journal 19910101
Phenytoin-induced choreoathetosis. Postgraduate medical journal 19901201
Sensorineural hearing loss: a reversible effect of valproic acid. Neurology 19901201
Cognitive function in adult epileptic patients established on anticonvulsant monotherapy. Epilepsy research 19901201
[Valproic acid and stupor]. Nederlands tijdschrift voor geneeskunde 19901027
[Choreoathetosis induced by diphenylhydantoin in and infant with CHARGE syndrome]. Anales espanoles de pediatria 19901001
Major effects on teratogen-induced facial clefting in mice determined by a single genetic region. Genetics 19900901
Hypotension during slow phenytoin infusion in severe sepsis. Critical care medicine 19900901
Phenytoin hypersensitivity. Maryland medical journal (Baltimore, Md. : 1985) 19900601
[A case of childhood choreoathetosis induced by diphenylhydantoin]. Anales espanoles de pediatria 19900601
Organic mania induced by phenytoin. Canadian journal of psychiatry. Revue canadienne de psychiatrie 19900601
[Oral administration of diphenylhydantoin sodium (DFH-Na or phenytoin) predictably affects the liver and kidney of Sprague Dawley rats]. Archivos de investigacion medica 19900101
Seizure-like activity during fentanyl anesthesia. A case report. Anesthesia progress 19900101
Effects of exposure period and nutrition on the developmental neurotoxicity of anticonvulsants in rats: short and long-term effects. Neurotoxicology 19900101
Busulphan and phenytoin. Annals of internal medicine 19891215
Inhibition of human immunodeficiency virus (HIV-1) infection by diphenylhydantoin (dilantin) implicates role of cellular calcium in virus life cycle. Virology 19891201
An atypical hypersensitivity reaction. Hospital practice (Office ed.) 19891115
Organic mania induced by phenytoin: a case report. Canadian journal of psychiatry. Revue canadienne de psychiatrie 19891101
Clinical experience with phenytoin prophylaxis in severe preeclampsia. American journal of obstetrics and gynecology 19891101
[Phenytoin ophthalmoplegia]. Neurologia (Barcelona, Spain) 19890901
Phenytoin induced fatal hepatic injury. Boletin de la Asociacion Medica de Puerto Rico 19890901
Phenytoin withdrawal and seizure frequency. Neurology 19890701
Phenytoin-induced hepatitis, rhabdomyolysis, and renal dysfunction. Clinical pharmacy 19890701
Valproic acid, unlike other anticonvulsants, has no effect on methadone metabolism: two cases. The Journal of clinical psychiatry 19890601
Cancer among epileptic patients exposed to anticonvulsant drugs. Journal of the National Cancer Institute 19890510
Selective killing of human T cell lymphotropic virus type I-transformed cell lines by a damavaricin Fc derivative. The Journal of antibiotics 19890501
Treatment of idiopathic parkinsonism with L-dopa in the absence and presence of decarboxylase inhibitors: effects on plasma levels of L-dopa, dopa decarboxylase, catecholamines and 3-O-methyl-dopa. Journal of neurology 19890501
Seizures associated with fluorescein angiography. Annals of ophthalmology 19890301
Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19890201
'Central' and 'peripheral' benzodiazepines and kinetics of lindane-induced toxicity. Pharmacology, biochemistry, and behavior 19890201
Valproic acid prenatal exposure. Association with lipomyelomeningocele. Clinical pediatrics 19890201
Halothane hepatitis: damage to peripheral blood mononuclear cells produced by electrophilic drug metabolites is Ca(2+)-dependent. Journal of gastroenterology and hepatology 19890101
Phenytoin-induced nephrotic syndrome. Nephron 19890101
A case of amyloidosis associated with diphenylhydantoin therapy. Japanese journal of medicine 19890101
Pharmacology of ACC-9653 (phenytoin prodrug). Epilepsia 19890101
Phenytoin-induced seizures: a paradoxical effect at toxic concentrations in epileptic patients. Epilepsia 19890101
Medical treatment of the major neuralgias. Seminars in neurology 19881201
Relative efficacy of phenytoin and phenobarbital for the prevention of theophylline-induced seizures in mice. Annals of emergency medicine 19881001
Long-lasting movement disorder induced by intravenous phenytoin administration for status epilepticus. A case report. Clinical neuropharmacology 19881001
Anticonvulsive and convulsive effects of lidocaine: comparison with those of phenytoin, and implications for mechanism of action concepts. Neurological research 19880901
Cardiopulmonary arrest following intravenous phenytoin loading. The American journal of emergency medicine 19880501
Phenytoin prophylaxis of cardiotoxicity in experimental amitriptyline poisoning. The Journal of pharmacology and experimental therapeutics 19880401
[Visual disorders caused by diphenylhydantoin: clinical and electro-ophthalmologic findings]. Klinische Monatsblatter fur Augenheilkunde 19880301
In-vivo effects of itraconazole on hepatic mixed-function oxidase. The Journal of antimicrobial chemotherapy 19880201
Study of the participation of the dopaminergic transmission system in the effects of two newly synthesized barbiturates. Acta physiologica et pharmacologica Bulgarica 19880101
Effects of antiepileptic drugs on absence-like and tonic seizures in the spontaneously epileptic rat, a double mutant rat. Epilepsia 19880101
Arachidonic acid reversal of phenytoin-induced neural tube and craniofacial defects in vitro in mice. Journal of craniofacial genetics and developmental biology 19880101
Clinical side effects of phenobarbital, primidone, phenytoin, carbamazepine, and valproate during monotherapy in children. Epilepsia 19880101
Phenytoin syndrome developing after administration of dilantin for an enflurane-induced seizure. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 19880101
Choreoathetosis induced by ordinary phenytoin levels, explained by high free fraction?--A case report. Therapeutic drug monitoring 19880101
[Hypersensitivity myocarditis probably due to phenytoin]. Nihon geka hokan. Archiv fur japanische Chirurgie 19880101
Elevated glucocorticoid receptor levels in lymphocytes of children with the fetal hydantoin syndrome (FHS). American journal of medical genetics 19871101
Phenytoin-induced hypersensitivity reactions. Clinical pharmacy 19870901
Effect of phenytoin on the mental and physical function of patients with Baltic myoclonus epilepsy. Italian journal of neurological sciences 19870801
Phenytoin toxicity and hepatic encephalopathy: simulation or stimulation? Journal of clinical gastroenterology 19870601
Transient chorea induced by phenytoin. The Journal of pediatrics 19870401
The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity. Toxicology and applied pharmacology 19870330
Investigations into the neuropharmacological basis of temporal stages of memory formation in mice trained in an active avoidance task. Behavioural brain research 19870301
Opsoclonus induced by phenytoin and diazepam. Annals of neurology 19870201
Phenytoin toxicity: a cause of reversible monoplegia. Cleveland Clinic journal of medicine 19870101
[Choreoathetotic movements in a patient with epilepsy after treatment with diphenylhydantoin]. Neurologia i neurochirurgia polska 19870101
Maze learning in rats: a comparison of performance in two water mazes in progeny prenatally exposed to different doses of phenytoin. Neurotoxicology and teratology 19870101
Phenytoin encephalopathy. The Journal of the Association of Physicians of India 19861101
Phenytoin hypersensitivity hepatitis and mononucleosis syndrome. Journal of clinical gastroenterology 19860801
Cholinergic induction of seizures in the rat prefrontal cortex. Life sciences 19860623
Tri-iodothyronine and phenytoin reduce prolactin messenger RNA levels in cultured rat pituitary cells. The Journal of endocrinology 19860601
Seizures associated with phenytoin toxicity. Clinical pharmacy 19860401
Dilantin-induced long-term bilateral total external ophthalmoplegia. Journal of clinical neuro-ophthalmology 19860301
Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death. Research communications in chemical pathology and pharmacology 19860301
Phenytoin-induced benign intracranial hypertension. Neurology 19860301
Phenytoin neuropathy: structural changes in the sural nerve. Annals of neurology 19860201
Phenytoin-induced systemic granulomatous vasculitis. Archives of pathology & laboratory medicine 19860201
A case of phenytoin toxicity possibly precipitated by trazodone. The Journal of clinical psychiatry 19860201
Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats. Epilepsia 19860101
Phenobarbital improves survival in theophylline-intoxicated rabbits. Journal of toxicology. Clinical toxicology 19860101
Incidence of seizures with phenytoin toxicity. Neurology 19851201
Halothane hepatitis. Detection of a constitutional susceptibility factor. The New England journal of medicine 19851121
Cardiac side effects of phenytoin and carbamazepine. A dose-related phenomenon? Archives of neurology 19851101
Anticonvulsant effects of chronic treatment with phenytoin against pentylenetetrazole-induced seizures in the mouse. Neuropharmacology 19851001
Quantitative vibration perception thresholds in patients under prolonged antiepileptic treatment. Acta neurologica Scandinavica 19850901
Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. Neurology 19850801
Dilantin-induced erythema multiforme major: report of a case with liver and kidney involvement. The Journal of the American Osteopathic Association 19850801
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. The New England journal of medicine 19850718
Aplastic anaemia induced by intravenous phenytoin and lidocaine administration. European journal of pediatrics 19850701
[Acute liver necrosis caused by valproate]. Deutsche medizinische Wochenschrift (1946) 19850614
Ependymoblastoma associated with prenatal exposure to diphenylhydantoin and methylphenobarbitone. Cancer 19850501
Stimulus-induced myoclonus and burst suppression on EEG: effects of phenytoin toxicity. Annals of neurology 19850301
Diphenylhydantoin encephalopathy. A case report. Acta neurologica 19850201
Etifoxine: evaluation of its anticonvulsant profile in mice in comparison with sodium valproate, phenytoin and clobazam. Arzneimittel-Forschung 19850101
Clinical and electrophysiologic evaluation of peripheral nerve function in chronic phenytoin therapy. Epilepsia 19850101
Diphenylhydantoin-induced hypersensitivity reaction with interstitial nephritis. Human pathology 19850101
Genetic variation in spontaneous and diphenylhydantoin-induced craniofacial malformations in mice. Journal of craniofacial genetics and developmental biology. Supplement 19850101
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat. Arzneimittel-Forschung 19850101
DDT-induced tremor in rats: effects of pharmacological agents. Psychopharmacology 19850101
Comparison of anticonvulsive properties of eboracin and phenytoin in mice. Pharmacology, biochemistry, and behavior 19850101
Damage of Purkinje cell axons following chronic phenytoin administration: an animal model of distal axonopathy. Acta neuropathologica 19850101
A case report of phenytoin encephalopathy. Correlation between serum levels, seizure increase and E.E.G. spike and wave activity. Clinical neurology and neurosurgery 19850101
Parkinsonism induced by phenytoin. Clinical neuropharmacology 19850101
The cerebellum of epileptics. Clinical neuropathology 19850101
Fetal anticonvulsant syndrome in rats: effects on postnatal behavior and brain amino acid content. Neurobehavioral toxicology and teratology 19850101
Glycine potentiates the action of some anticonvulsant drugs in some seizure models. Neurochemical research 19841201
Slow saccades and hypometria in anticonvulsant toxicity. Neurology 19841201
Interaction of amiodarone and diphenylhydantoin. The American journal of cardiology 19841101
Role of vagus in the antagonism of ouabain induced arrhythmias in dogs by beta-adrenoceptor antagonists and related drugs. The Journal of pharmacy and pharmacology 19841001
Focal dystonic reaction to phenytoin. Developmental medicine and child neurology 19841001
Maprotiline hydrochloride associated with a clinical state of catatonic stupor and epileptic encephalogram. Journal of clinical psychopharmacology 19840801
Effect of some beta adrenergic blocking agents and phenytoin on potentiation of quinidine antiarrhythmic activity in the mouse. Archives internationales de pharmacodynamie et de therapie 19840701
Seizures due to maprotiline overdose. Annals of emergency medicine 19840601
Phenytoin potentiates methamphetamine-induced behavior in mice. Pharmacology, biochemistry, and behavior 19840501
Cholestatic liver dysfunction after long-term phenytoin therapy. Archives of neurology 19840501
Compromised hepatic function in dogs treated with anticonvulsant drugs. Journal of the American Veterinary Medical Association 19840215
The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice. British journal of cancer 19840201
Total external ophthalmoplegia induced by phenytoin. A case report. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 19840128
Impaired phenytoin bioavailability secondary to cisplatinum, vinblastine, and bleomycin. Therapeutic drug monitoring 19840101
[Phenytoin-induced paroxysmal choreoathetosis]. Padiatrie und Grenzgebiete 19840101
Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide. Hormone research 19840101
The influence of carbamazepine and phenytoin on memory and other aspects of cognitive function in new referrals with epilepsy. Acta neurologica Scandinavica. Supplementum 19840101
Dementia in epilepsy. Acta neurologica Scandinavica. Supplementum 19840101
Universal cutaneous depigmentation following phenytoin-induced toxic epidermal necrolysis. Journal of the American Academy of Dermatology 19840101
Tubular aggregates in a case of osteomalacic myopathy due to anticonvulsant drugs. Clinical neuropathology 19840101
Phenytoin-induced choreoathetosis in infancy: case reports and a review. Pediatrics 19831201
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. The Journal of pharmacology and experimental therapeutics 19831101
The role of microsomal enzyme inducers in the reduction of misonidazole neurotoxicity. The British journal of radiology 19831101
The role of dexamethasone in the modification of misonidazole pharmacokinetics. British journal of cancer 19831001
Central nervous system supersensitivity and withdrawal from long-term diphenylhydantoin treatment. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 19831001
Transient hemiparesis caused by phenytoin toxicity. A case report. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 19830924
Transient hemiparesis--a rare complication of phenytoin toxicity. Postgraduate medical journal 19830901
Phenytoin-induced dystonia. Annals of neurology 19830701
Myopathy and hypersensitivity to phenytoin. Neurology 19830601
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19830501
Delirium with phenytoin and disulfiram administration. Annals of emergency medicine 19830501
Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro. Blood 19830501
Phenytoin teratogenicity in the primary and secondary mouse embryonic palate is influenced by the H-2 histocompatibility locus. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19830501
Complications of intravenous phenytoin for acute treatment of seizures. Recommendations for usage. JAMA 19830211
Necrotizing vasculitis associated with diphenylhydantoin: two fatal cases. Human pathology 19830201
Anticonvulsant sensitivity of absence seizures in the tottering mutant mouse. Epilepsia 19830201
Effective plasma concentrations of antiarrhythmic drugs against sustained halothane-adrenaline arrhythmia in dogs. Journal of cardiovascular pharmacology 19830101
Peripheral nerve damage in epileptic patients treated with phenytoin. East African medical journal 19830101
Possible mechanism of digoxin-induced convulsions. Psychopharmacology 19830101
Neurobiological studies of experimental diphenylhydantoin intoxication--III. Electron microscopic studies on development and disintegration mechanism of altered axon terminals and synaptic endings in rat cerebellum with chronic diphenylhydantoin intoxication. Folia psychiatrica et neurologica japonica 19830101
Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations. Japanese circulation journal 19830101
The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications. Circulation 19830101
Susceptibility to phenytoin-induced cleft palate in mice is influenced by genes linked to H-2 and H-3. Immunogenetics 19830101
Downbeat nystagmus with phenytoin. Journal of clinical neuro-ophthalmology 19820901
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates. Journal of neurology, neurosurgery, and psychiatry 19820701
Unidirectional gaze paretic nystagmus induced by phenytoin intoxication. American journal of ophthalmology 19820701
Stuporous episodes during treatment with sodium valproate: report of seven cases. Epilepsia 19820601
Cardiovascular response to rapid phenytoin infusion during seizures in paralyzed rats. Archives of neurology 19820601
Dilantin toxicity in a preterm infant: persistent bradycardia and lethargy. The Journal of pediatrics 19820101
Plasma exchange in the successful treatment of drug-induced renal disease. Nephron 19820101
[Pharmacological studies on the functional development of the central nervous system in first generation rats born to phenytoin-treated mothers (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19820101
Behavioural effects of phenobarbitone and phenytoin in small children. Archives of disease in childhood 19811101
A prolonged severe intoxication after ingestion of phenytoin and phenobarbital. The Western journal of medicine 19811101
[Diphenylhydantoin, epilepsy, cerebellar atrophy--histological and electron microscope examinations (author's transl)]. Fortschritte der Neurologie-Psychiatrie 19811101
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