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773-76-2 | 5,7-Dichloroquinolin-8-ol
CAS No: 773-76-2 Catalog No: AG003MAN MDL No:MFCD00006786
Product Description
Catalog Number:
AG003MAN
Chemical Name:
5,7-Dichloroquinolin-8-ol
CAS Number:
773-76-2
Molecular Formula:
C9H5Cl2NO
Molecular Weight:
214.0481
MDL Number:
MFCD00006786
IUPAC Name:
5,7-dichloroquinolin-8-ol
InChI:
InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI Key:
WDFKMLRRRCGAKS-UHFFFAOYSA-N
SMILES:
Clc1cc(Cl)c2c(c1O)nccc2
EC Number:
212-258-3
UNII:
2I8BD50I8B
Properties
Complexity:
191
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
212.975g/mol
Formal Charge:
0
Heavy Atom Count:
13
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
214.045g/mol
Monoisotopic Mass:
212.975g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
33.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.5
Literature
| Title | Journal |
|---|---|
| Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction. | Journal of medicinal chemistry 20130328 |
| Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode. | Journal of fluorescence 20120901 |
| Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. | Journal of medicinal chemistry 20110811 |
| Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy. | Nature chemical biology 20110601 |
| High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides. | Dalton transactions (Cambridge, England : 2003) 20110227 |
| 8-Hy-droxy-2-methyl-quinolinium tetra-chlorido(quinolin-2-olato-κN,O)stannate(IV) methanol disolvate. | Acta crystallographica. Section E, Structure reports online 20110201 |
| Synthesis and characterization of nano-pore thallium (III) ion-imprinted polymer as a new sorbent for separation and preconcentration of thallium. | Journal of hazardous materials 20110115 |
| Identification of clinically used drugs that activate pregnane X receptors. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats. | PloS one 20110101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| N,N-Dicyclo-hexyl-2-(5,7-dichloro-8-quinol-yloxy)acetamide. | Acta crystallographica. Section E, Structure reports online 20091101 |
| 5,7-Dichloro-quinolin-8-ol. | Acta crystallographica. Section E, Structure reports online 20090501 |
| Synthesis of nano-pore samarium (III)-imprinted polymer for preconcentrative separation of samarium ions from other lanthanide ions via solid phase extraction. | Analytica chimica acta 20080808 |
| Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands. | The Biochemical journal 20071101 |
| Investigation of the role of chelating ligand in the synthesis of ion-imprinted polymeric resins on the selective enrichment of uranium(VI). | Analytica chimica acta 20070328 |
| Ion imprinted polymer particles for separation of yttrium from selected lanthanides. | Journal of separation science 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| The evaluation of liposome-water partitioning of 8-hydroxyquinolines and their copper complexes. | Environmental science & technology 20060315 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Solid phase extraction preconcentration of cobalt and nickel with 5,7-dichloroquinone-8-ol embedded styrene-ethylene glycol dimethacrylate polymer particles and determination by flame atomic absorption spectrometry (FAAS). | Talanta 20050415 |
| Selective recognition of neodymium (III) using ion imprinted polymer particles. | Journal of molecular recognition : JMR 20050101 |
| Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. | Breast cancer research : BCR 20050101 |
| A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions. | The Journal of biological chemistry 20040220 |
| Solid phase extractive preconcentration of thorium onto 5,7-dichloroquinoline-8-ol modified benzophenone. | Talanta 20021016 |
| Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites. | Mutation research 19940501 |
| Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action. | IARC scientific publications 19910101 |
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