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77094-11-2 | 3H-Imidazo[4,5-f]quinolin-2-amine,3,4-dimethyl-
CAS No: 77094-11-2 Catalog No: AG00566L MDL No:
Product Description
Catalog Number:
AG00566L
Chemical Name:
3H-Imidazo[4,5-f]quinolin-2-amine,3,4-dimethyl-
CAS Number:
77094-11-2
Molecular Formula:
C12H12N4
Molecular Weight:
212.2505
IUPAC Name:
3,4-dimethylimidazo[4,5-f]quinolin-2-amine
InChI:
InChI=1S/C12H12N4/c1-7-6-9-8(4-3-5-14-9)10-11(7)16(2)12(13)15-10/h3-6H,1-2H3,(H2,13,15)
InChI Key:
GMGWMIJIGUYNAY-UHFFFAOYSA-N
SMILES:
Cc1cc2ncccc2c2c1n(C)c(n2)N
UNII:
G2Q7M1P33X
Properties
Complexity:
270
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
212.106g/mol
Formal Charge:
0
Heavy Atom Count:
16
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
212.256g/mol
Monoisotopic Mass:
212.106g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
56.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2
Literature
| Title | Journal |
|---|---|
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| A comparison of whole wheat, refined wheat and wheat bran as inhibitors of heterocyclic amines in the Salmonella mutagenicity assay and in the rat colonic aberrant crypt focus assay. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701 |
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| Chromosome aberrations induced in mice by chronic feeding of 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19980601 |
| No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue mice. | Mutation research 19980525 |
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| Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines. | Princess Takamatsu symposia 19950101 |
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| Genetic alterations in HCA-induced tumors. | Princess Takamatsu symposia 19950101 |
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| Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats. | Cancer letters 19940829 |
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| Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses. | Carcinogenesis 19910501 |
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| Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline. | Carcinogenesis 19890301 |
| Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens. | Chemico-biological interactions 19880101 |
| Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline. | Carcinogenesis 19861101 |
| Carcinogenicity in mice and rats of heterocyclic amines in cooked foods. | Environmental health perspectives 19860801 |
| Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. | Princess Takamatsu symposia 19850101 |
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