CAS 75438-57-2 | moxonidine | CAS Number 75438-57-2

Title	Journal
The protective effects of metyrosine, lacidipine, clonidine, and moxonidine on kidney damage induced by unilateral ureteral obstruction in rats.	Surgery today 20121101
Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance.	Journal of hypertension 20121001
Pharmacological properties of the central antihypertensive agent, moxonidine.	Cardiovascular therapeutics 20120801
Adenosinergic modulation of the imidazoline I₁-receptor-dependent hypotensive effect of ethanol in acute renal failure.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
The human sympathetic nervous system: its relevance in hypertension and heart failure.	European heart journal 20120501
Moxonidine-induced priapism in an autosomal-dominant polycystic kidney disease dialysis patient.	Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120501
Moxonidine into the lateral parabrachial nucleus reduces renal and hormonal responses to cell dehydration.	Neuroscience 20120419
Crosstalk between central pathways of nitric oxide and carbon monoxide in the hypertensive action of cyclosporine.	Neuropharmacology 20120301
Development and validation of reversed phase high performance liquid chromatographic method for determination of moxonidine in the presence of its impurities.	Journal of pharmaceutical and biomedical analysis 20120205
Effects of imidazolines on neurogenic contraction in isolated urinary bladder detrusor strips from rabbit.	Canadian journal of physiology and pharmacology 20120201
Sympathoexcitation by brain oxidative stress mediates arterial pressure elevation in salt-induced chronic kidney disease.	Hypertension (Dallas, Tex. : 1979) 20120101
How full is our antihypertensives pipeline?	Journal of pharmacology & pharmacotherapeutics 20120101
An 'I' on cardiac hypertrophic remodelling: imidazoline receptors and heart disease.	The Canadian journal of cardiology 20120101
Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.	PloS one 20120101
Morphine and clonidine synergize to ameliorate low back pain in mice.	Pain research and treatment 20120101
Sympatho-renal axis in chronic disease.	Clinical research in cardiology : official journal of the German Cardiac Society 20111201
Changes in taste reactivity to intra-oral hypertonic NaCl after lateral parabrachial injections of an α2-adrenergic receptor agonist.	Physiology & behavior 20111024
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.	Biological psychiatry 20111015
Moxonidine improves cardiac structure and performance in SHR through inhibition of cytokines, p38 MAPK and Akt.	British journal of pharmacology 20111001
Percutaneous renal denervation for the treatment of resistant essential hypertension; the first Dutch experience.	Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110801
Pecularities of prolonged use of moxonidine in patients with hypertension associated with metabolic syndrome.	Bulletin of experimental biology and medicine 20110801
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	Journal of medicinal chemistry 20110714
Modulation of N-type Ca²⁺ currents by moxonidine via imidazoline I₁ receptor activation in rat superior cervical ganglion neurons.	Biochemical and biophysical research communications 20110617
Scintigraphic diagnosis of Erdheim-Chester disease.	Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601
[The efficacy and safety of moxonidine in patients with metabolic syndrome (the O.B.E.Z.I.T.A. trial)].	Vnitrni lekarstvi 20110601
Functional and molecular effects of imidazoline receptor activation in heart failure.	Life sciences 20110314
GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidine.	Cardiovascular research 20110201
High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy.	PloS one 20110101
Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism.	PloS one 20110101
PKreport: report generation for checking population pharmacokinetic model assumptions.	BMC medical informatics and decision making 20110101
[Possibilities of the use of moxonidine in the treatment of arterial hypertension in patients with metabolic syndrome and diabetes].	Kardiologiia 20110101
[Acute management at the rising of arterial pressure which is not menacing to a life].	Kardiologiia 20110101
Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain.	Journal of pain research 20110101
Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.	The open cardiovascular medicine journal 20110101
The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat.	International journal of nephrology 20110101
[Analysis of efficacy and safety of administration of moxonidine in patients with arterial hypertension and hypertensive crises].	Kardiologiia 20110101
Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients.	Journal of cardiovascular disease research 20110101
Estrogen receptor alpha expression in podocytes mediates protection against apoptosis in-vitro and in-vivo.	PloS one 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.	Bioorganic & medicinal chemistry letters 20101101
Effects of moxonidine on sympathetic nerve activity in patients with end-stage renal disease.	Journal of hypertension 20100901
Acute effects of moxonidine on cardiac autonomic modulation.	Pacing and clinical electrophysiology : PACE 20100801
A model of hypertension and proteinuria in cancer patients treated with the anti-angiogenic drug E7080.	Journal of pharmacokinetics and pharmacodynamics 20100801
Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats.	European journal of pharmacology 20100710
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.	Human molecular genetics 20100601
Successful treatment of cold-induced sweating in Crisponi syndrome and its possible mechanism of action.	Developmental medicine and child neurology 20100501
Effect of moxonidine and amlodipine on serum YKL-40, plasma lipids and insulin sensitivity in insulin-resistant hypertensive patients-a randomized, crossover trial.	Hypertension research : official journal of the Japanese Society of Hypertension 20100401
Microvascular effects of centrally acting antihypertensive drugs in spontaneously hypertensive rats.	Journal of cardiovascular pharmacology 20100301
[Combination therapy of hypertension in general clinical practice. The results of the KOHYBA study].	Vnitrni lekarstvi 20100301
Lateral parabrachial nucleus and central amygdala in the control of sodium intake.	Neuroscience 20100203
Comparable renovascular protective effects of moxonidine and simvastatin in rats exposed to cigarette smoke.	Vascular pharmacology 20100101
Experimental models of renal disease and the cardiovascular system.	The open cardiovascular medicine journal 20100101
Anorexia nervosa depends on adrenal sympathetic hyperactivity: opposite neuroautonomic profile of hyperinsulinism syndrome.	Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Critical appraisal of the differential effects of antihypertensive agents on arterial stiffness.	Integrated blood pressure control 20100101
Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins.	Neurochemistry international 20091201
Adrenergic mechanisms of the Kölliker-Fuse/A7 area on the control of water and sodium intake.	Neuroscience 20091201
Rare psychotropic adverse event of moxonidine.	Psychiatria Danubina 20091201
Low dose of moxonidine within the rostral ventrolateral medulla improves the baroreflex sensitivity control of sympathetic activity in hypertensive rat.	Acta pharmacologica Sinica 20091201
Sympathoinhibitory mechanism of moxonidine: role of the inducible nitric oxide synthase in the rostral ventrolateral medulla.	Cardiovascular research 20091101
Facilitation of central imidazoline I(1)-site/extracellular signal-regulated kinase/p38 mitogen-activated protein kinase signalling mediates the hypotensive effect of ethanol in rats with acute renal failure.	British journal of pharmacology 20091101
Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.	The Biochemical journal 20091023
Pharmacological characterization of the inhibition by moxonidine and agmatine on the cardioaccelerator sympathetic outflow in pithed rats.	European journal of pharmacology 20090815
Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis.	Pharmacology & therapeutics 20090801
Comparison of agmatine with moxonidine and rilmenidine in morphine dependence in vitro: role of imidazoline I(1) receptors.	European journal of pharmacology 20090610
Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats.	Hypertension (Dallas, Tex. : 1979) 20090501
A preliminary report on the prognostic significance of preoperative brain natriuretic peptide and postoperative cardiac troponin in patients undergoing major vascular surgery.	Anesthesia and analgesia 20090401
Involvement of central alpha1-adrenoceptors on renal responses to central moxonidine and alpha-methylnoradrenaline.	European journal of pharmacology 20090401
Effect of moxonidine on the uveoscleral outflow: role of alpha2-adrenoceptors or i1 imidazoline receptors.	Current eye research 20090401
Testing conception of engagement of imidazoline receptors in imidazoline drugs effects on isolated rat heart atria.	Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301
Activation of alpha(2)-adrenoceptors in the lateral hypothalamus reduces pilocarpine-induced salivation in rats.	Neuroscience letters 20090206
Moxonidine prevents ischemia/reperfusion-induced renal injury in rats.	European journal of pharmacology 20090128
Interruption of central neuronal pathway of imidazoline I1 receptor mediates the hypertensive effect of cyclosporine in rats.	Brain research 20090112
Solvay addresses unmet needs in the management of hypertensive patients with cardiometabolic and lipid disorders.	Cardiovascular journal of Africa 20090101
Generation and characterization of novel human IRAS monoclonal antibodies.	Journal of biomedicine & biotechnology 20090101
Drugs associated with more suicidal ideations are also associated with more suicide attempts.	PloS one 20090101
An immunocompetent patient presenting with severe septic arthritis due to Ralstonia pickettii identified by molecular-based assays: a case report.	Cases journal 20090101
Protection in glutamate-induced neurotoxicity by imidazoline receptor agonist moxonidine.	The International journal of neuroscience 20090101
Implication of enterohepatic re-circulation on single dose bioequivalence evaluation of two brands of clonidine hydrochloride tablets in healthy human volunteers.	Indian journal of pharmaceutical sciences 20090101
Evidence that some imidazoline derivatives inhibit peripherally the vasopressor sympathetic outflow in pithed rats.	Autonomic neuroscience : basic & clinical 20081205
Addressing the relationship between sympathetic activity and inflammation.	Journal of hypertension 20081201
Central sympatholytic therapy has anti-inflammatory properties in hypertensive postmenopausal women.	Journal of hypertension 20081201
Biphasic dose-dependent modulation of cardiac parasympathetic activity by moxonidine, an imidazoline I1-receptor agonist.	Journal of cardiovascular pharmacology 20081201
Acute poisoning with moxonidine? A case report.	Clinical toxicology (Philadelphia, Pa.) 20081101
American College of Endocrinology Pre-Diabetes Consensus Conference: part two.	Diabetes care 20081101
[Arterial hypertension - dosing recommendations at beginning and end of treatment].	Therapeutische Umschau. Revue therapeutique 20081001
Clinical profile of eprosartan: a different angiotensin II receptor blocker.	Cardiovascular & hematological agents in medicinal chemistry 20081001
Principles for different modes of multiple-injection CZE.	Electrophoresis 20081001
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation.	Current neuropharmacology 20080901
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.	Current neuropharmacology 20080901
QSAR study of imidazoline antihypertensive drugs.	Bioorganic & medicinal chemistry 20080801
Potentiation by yohimbine of alpha-adrenoceptor-mediated vasoconstriction in response to clonidine in the rabbit ear vein.	European journal of pharmacology 20080728
Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease.	European journal of pharmacology 20080728
Effects of spinal alpha(2)-adrenoceptor and I(1)-imidazoline receptor activation on hindlimb movement induction in spinal cord-injured mice.	The Journal of pharmacology and experimental therapeutics 20080601
Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation.	British journal of pharmacology 20080201
Effects of sympatholytic therapy with moxonidine on serum adiponectin levels in hypertensive women.	The Journal of international medical research 20080101
[Effect of antihypertensive agents from various pharmacological groups on blood pressure reaction during stress-testing. Part I. Comparative characteristics of medications, exerting effect of sympathoadrenal block].	Kardiologiia 20080101
[The efficiency of combinations of Enalapril and long-acting Nifedipin and Moxonidine in patients with arterial hypertension and a metabolic syndrome].	Klinicheskaia meditsina 20080101
[The influence of antihypertensive agents on plasmatic and vascular-thrombocytic homeostasis in metabolic syndrome].	Eksperimental'naia i klinicheskaia farmakologiia 20080101
S1P-receptors in PC12 and transfected HEK293 cells: molecular targets of hypotensive imidazoline I(1) receptor ligands.	Neurochemistry international 20071201
Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method.	Pharmaceutical research 20071201
Randomized clinical trial of moxonidine in patients undergoing major vascular surgery.	The British journal of surgery 20071201
Peroxynitrite is Involved in the dysfunction of vasorelaxation in SHR/NDmcr-cp rats, spontaneously hypertensive obese rats.	Journal of cardiovascular pharmacology 20071201
Enhancement of meal-associated hypertonic NaCl intake by moxonidine into the lateral parabrachial nucleus.	Behavioural brain research 20071102
Sympathoexcitation of moxonidine in the caudal ventrolateral medulla is dependent on I1-imidazoline receptors in anesthetized rats.	Neuroscience letters 20071016
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies.	Journal of pharmacokinetics and pharmacodynamics 20071001
Clonidine, moxonidine, folic acid, and mecobalamin improve baroreflex function in stroke-prone, spontaneously hypertensive rats.	Acta pharmacologica Sinica 20071001
Comparative study of NMDA and AMPA/kainate receptors involved in cardiovascular inhibition produced by imidazoline-like drugs in anaesthetized rats.	Experimental physiology 20070901
Effects of sympatholytic therapy on insulin sensitivity indices in hypertensive postmenopausal women.	International journal of clinical pharmacology and therapeutics 20070701
Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test.	European journal of pharmacology 20070622
Involvement of central alpha1- and alpha2-adrenoceptors on cardiovascular responses to moxonidine.	European journal of pharmacology 20070601
Centrally acting antihypertensive agents: an update.	Journal of clinical hypertension (Greenwich, Conn.) 20070501
Identification of IRAS/Nischarin as an I1-imidazoline receptor in PC12 rat pheochromocytoma cells.	Journal of neurochemistry 20070401
Metabolic and antihypertensive effects of moxonidine and moxonidine plus irbesartan in patients with type 2 diabetes mellitus and mild hypertension: a sequential, randomized, double-blind clinical trial.	Clinical therapeutics 20070401
Marked insulin resistance in obese spontaneously hypertensive rat adipocytes is ameliorated by in vivo but not in vitro treatment with moxonidine.	The Journal of pharmacology and experimental therapeutics 20070201
Adjunctive treatment with moxonidine versus nitrendipine for hypertensive patients with advanced renal failure: a cost-effectiveness analysis.	BMC nephrology 20070101
Moxonidine improves glycaemic control in mildly hypertensive, overweight type 2 diabetic patients.	Cardiovascular journal of Africa 20070101
[Arterial hypertension in extreme situations].	Klinicheskaia meditsina 20070101
Characterization of an antiproliferative effect of imidazoline receptor ligands on PC12 cells.	Pharmacological reports : PR 20070101
Alpha2-adrenergic activation in the lateral parabrachial nucleus induces NaCl intake under conditions of systemic hyperosmolarity.	Neuroscience 20060929
Involvement of phosphatidylcholine-selective phospholipase C in activation of mitogen-activated protein kinase pathways in imidazoline receptor antisera-selected protein.	Journal of cellular biochemistry 20060815
Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.	European journal of pharmacology 20060710
Moxonidine improves glycaemic control in mildly hypertensive, overweight patients: a comparison with metformin.	Diabetes, obesity & metabolism 20060701
Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide.	Journal of cardiovascular pharmacology 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa.	Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Selective imidazoline agonist moxonidine in obese hypertensive patients.	International journal of clinical practice 20060501
[The modulatory influence of moxonidine on the different link of sympatho-adrenal system and hemodynamic reactions in normo and hypertensive rats during emotional stress].	Georgian medical news 20060401
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.	Bioorganic & medicinal chemistry 20060315
Influence of central inhibition of sympathetic nervous activity on myocardial metabolism in chronic heart failure: acute effects of the imidazoline I1-receptor agonist moxonidine.	Clinical science (London, England : 1979) 20060301
Effects of eprosartan on target organ protection.	Vascular health and risk management 20060301
Presynaptic I1-imidazoline receptors reduce GABAergic synaptic transmission in striatal medium spiny neurons.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208
Determination of moxonidine in human plasma by liquid chromatography-electrospray ionisation-mass spectrometry.	Journal of pharmaceutical and biomedical analysis 20060123
Insulin resistance and sympathetic overactivity in women.	Journal of hypertension 20060101
Cause and consequences of sympathetic hyperactivity in chronic kidney disease.	Blood purification 20060101
Lipid-lowering actions of imidazoline antihypertensive agents in metabolic syndrome X.	Naunyn-Schmiedeberg's archives of pharmacology 20060101
Moxonidine: a review of its use in essential hypertension.	Drugs 20060101
[Comparison of the effectiveness of moxonidine and prestarium in postmenopausal women with mild and moderate arterial hypertension].	Klinicheskaia meditsina 20060101
[The use of moxonidine in women with arterial hypertension in postmenopausal period].	Kardiologiia 20060101
Centrally acting imidazolines stimulate vascular alpha 1A-adrenergic receptors in Rat-Tail Artery.	Cellular and molecular neurobiology 20060101
Moxonidine well tolerated and effective in the treatment of viscerally obese, non-controlled hypertensive patients.	Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101
The effect of moxonidine on endothelial dysfunction in metabolic syndrome.	American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Imidazoline receptors in relaxation of acetylcholine-constricted isolated rat jejunum.	Pharmacological reports : PR 20060101
Identification of the central imidazoline receptor subtype involved in modulation of halothane-epinephrine arrhythmias in rats.	Anesthesia and analgesia 20051201
Use of moxonidine in elderly patients with resistant hypertension.	Journal of clinical pharmacy and therapeutics 20051001
[Antihypertensive therapy and drug-drug interactions].	Revue medicale suisse 20050914
Urinary responses to acute moxonidine are inhibited by natriuretic peptide receptor antagonist.	British journal of pharmacology 20050501
Non-adrenergic inhibition at prejunctional sites by agmatine of purinergic vasoconstriction in rabbit saphenous artery.	Neuropharmacology 20050301
Efficacy of moxonidine in the treatment of hypertension in obese, noncontrolled hypertensive patients.	Kidney international. Supplement 20050101
Application of population pharmacokinetics to cladribine.	BMC pharmacology 20050101
[Clinicogenetic aspects of carbohydrate metabolism disorders and efficacy of their correction with moxonidine and metformine in patients with arterial hypertension].	Terapevticheskii arkhiv 20050101
[The role of alpha2-adrenergic and I1-imidazoline receptors in the effects of clonidine and moxonidine on isolated large intestine of mice].	Eksperimental'naia i klinicheskaia farmakologiia 20050101
Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine.	Neuroscience 20050101
Moxonidine suitable for hypertensive menopausal women with metabolic syndrome.	Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101
Cardiovascular and survival effects of sympatho-inhibitors in adriamycin-induced cardiomyopathy in rats.	Fundamental & clinical pharmacology 20041201
Different effects of losartan and moxonidine on endothelial function during sympathetic activation in essential hypertension.	Journal of clinical hypertension (Greenwich, Conn.) 20041201
Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.	Journal of the American Society of Nephrology : JASN 20041101
The data monitoring experience in the MOXCON trial.	European heart journal 20041101
New pharmacological strategies in chronic heart failure.	Cardiovascular drugs and therapy 20041101
Modulation of gene expression by moxonidine in rats with chronic renal failure.	Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901
Moxonidine in the treatment of overweight and obese patients with the metabolic syndrome: a postmarketing surveillance study.	Journal of human hypertension 20040901
Imidazoline receptors but not alpha 2-adrenoceptors are regulated in spontaneously hypertensive rat heart by chronic moxonidine treatment.	The Journal of pharmacology and experimental therapeutics 20040801
Imidazoline receptors in the heart: a novel target and a novel mechanism of action that involves atrial natriuretic peptides.	Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040801
Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy.	American journal of physiology. Heart and circulatory physiology 20040701
Increased infarct size in uremic rats: reduced ischemia tolerance?	Journal of the American Society of Nephrology : JASN 20040601
Central blockade of nitric oxide synthesis reduces moxonidine-induced hypotension.	British journal of pharmacology 20040601
Effects of moxonidine vs. metoprolol on blood pressure and metabolic control in hypertensive subjects with type 2 diabetes.	Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040601
Moxonidine and rilmenidine injected into the medial septal area reduces the salivation induced by pilocarpine.	Autonomic neuroscience : basic & clinical 20040531
Effect of i1 imidazoline receptor agonist, moxonidine, in nitric oxide-deficient hypertension in pregnant rats.	Journal of cardiovascular pharmacology 20040501
The I1-imidazoline agonist moxonidine decreases sympathetic tone under physical and mental stress.	British journal of clinical pharmacology 20040501
Effect of moxonidine on lipid subfractions in patients with hypertension.	International journal of clinical practice 20040501
Selective imidazoline agonist moxonidine plus the ACE inhibitor ramipril in hypertensive patients with impaired insulin sensitivity: partners in a successful MARRIAGE?	Current medical research and opinion 20040301
The metabolic syndrome in women: implications for therapy.	International journal of clinical practice. Supplement 20040301
Treatment of postmenopausal hypertension with moxonidine, a selective imidazoline receptor agonist.	International journal of clinical practice. Supplement 20040301
Effect of moxonidine on contractile activity of isolated large intestine in mice: role of alpha2-adrenoceptors and Ii-imidazoline receptors.	Bulletin of experimental biology and medicine 20040301
Pharmacological therapy can increase capillary density in post-infarction remodeled rat hearts.	Cardiovascular research 20040215
Moxonidine, an antihypertensive agent, is permissive to alpha1-adrenergic receptor pathway in the rat-tail artery.	Journal of cardiovascular pharmacology 20040201
The effects of imidazoline agents on the aggregation of human platelets.	The Journal of pharmacy and pharmacology 20040201
Elevated sympathetic activity may promote insulin resistance syndrome by activating alpha-1 adrenergic receptors on adipocytes.	Medical hypotheses 20040101
Effect of moxonidine on putative sympathetic neurons in the rostral ventrolateral medulla of the rat.	Neuro-Signals 20040101
[Effect of moxonidine on parameters of lipid metabolism in patients with metabolic syndrome.].	Kardiologiia 20040101
Activation of alpha2-adrenergic receptors into the lateral parabrachial nucleus enhances NaCl intake in rats.	Neuroscience 20040101
[The role of hypersympathycotony in development of arterial hypertension in patients with metabolic syndrome: potential of pathogenetically sound therapy].	Terapevticheskii arkhiv 20040101
Moxonidine and central alpha2 adrenergic receptors in sodium intake.	Brain research 20031212
Contrasting metabolic effects of antihypertensive agents.	The Journal of pharmacology and experimental therapeutics 20031201
Electrophysiological responses to imidazoline/alpha2-receptor agonists in rabbit sinoatrial node pacemaker cells.	Acta pharmacologica Sinica 20031201
Identification and pharmacological characterization of a specific agmatine transport system in human tumor cell lines.	Annals of the New York Academy of Sciences 20031201
Cardiac effects of moxonidine in spontaneously hypertensive obese rats.	Annals of the New York Academy of Sciences 20031201
The role of I(1)-imidazoline receptors and alpha(2)-adrenergic receptors in the modulation of glucose and lipid metabolism in the SHROB model of metabolic syndrome X.	Annals of the New York Academy of Sciences 20031201
Involvement of forebrain imidazoline and alpha(2)-adrenergic receptors in the antidipsogenic response to moxonidine.	Annals of the New York Academy of Sciences 20031201
Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors.	Annals of the New York Academy of Sciences 20031201
Norepinephrine release is reduced by I(1)-receptors in addition to alpha(2)-adrenoceptors.	Annals of the New York Academy of Sciences 20031201
Normalization of up-regulated cardiac imidazoline I(1)-receptors and natriuretic peptides by chronic treatment with moxonidine in spontaneously hypertensive rats.	Annals of the New York Academy of Sciences 20031201
Apparent absence of direct renal effect of imidazoline receptor agonists.	Annals of the New York Academy of Sciences 20031201
Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia.	Annals of the New York Academy of Sciences 20031201
Central moxonidine on salivary gland blood flow and cardiovascular responses to pilocarpine.	Brain research 20031017
Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON).	European journal of heart failure 20031001
Moxonidine treatment of hypertensive patients with advanced renal failure.	Journal of hypertension 20030901
The role of I(1)-imidazoline and alpha(2)-adrenergic receptors in the modulation of glucose metabolism in the spontaneously hypertensive obese rat model of metabolic syndrome X.	The Journal of pharmacology and experimental therapeutics 20030801
The I(1)-imidazoline receptor in PC12 pheochromocytoma cells reverses NGF-induced ERK activation and induces MKP-2 phosphatase.	Brain research 20030801
Effects of moxonidine and metoprolol in penile circulation in hypertensive men with erectile dysfunction: results of a pilot study.	International journal of impotence research 20030801
[Study examines prescriptions for hypertension. Physicians adhering to guidelines very well].	MMW Fortschritte der Medizin 20030619
Central nervous system effects of moxonidine experimental sustained release formulation in patients with mild to moderate essential hypertension.	British journal of clinical pharmacology 20030601
Experimental approach to differentiation of the effects mediated by imidazole receptors and alpha2-adrenoceptors on platelets.	Bulletin of experimental biology and medicine 20030601
Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.	Journal of medicinal chemistry 20030508
[Ambulatory monitoring of blood pressure in regular dialysis therapy].	Vnitrni lekarstvi 20030401
Metabolism and disposition of the antihypertensive agent moxonidine in humans.	Drug metabolism and disposition: the biological fate of chemicals 20030301
Modification of noradrenaline release in pithed spontaneously hypertensive rats by I1-binding sites in addition to alpha2-adrenoceptors.	The Journal of pharmacology and experimental therapeutics 20030301
Dual effect of agmatine in the bisected rat vas deferens.	The Journal of pharmacy and pharmacology 20030301
Non-adrenergic exploratory behavior induced by moxonidine at mildly hypotensive doses.	Brain research 20030221
Central alpha(2) adrenergic receptors and cholinergic-induced salivation in rats.	Brain research bulletin 20030130
[Moxonidine is advantageous for hypertensive type 2 diabetic patients. Therapy of hypertension also lowers HbA1c].	MMW Fortschritte der Medizin 20030116
Importance of imidazoline-preferring receptors in the cardiovascular actions of chronically administered moxonidine, rilmenidine and clonidine in conscious rabbits.	Journal of hypertension 20030101
[The use of moxonidine in patients with essential hypertension combined with metabolic syndrome].	Kardiologiia 20030101
Antihypertensive efficacy of moxonidine in primary care: a 'real-life' study.	International journal of clinical practice 20030101
[Current views on migraine and anti-migraine preparations].	Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101
[Effect of imidazoline receptor agonist moxonidine on the state of microcirculation and renal function in patients with hypertension and diabetes mellitus type 2].	Kardiologiia 20030101
Plasma catecholamines and chronic congestive heart failure.	Circulation 20021217
Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors.	The Journal of pharmacology and experimental therapeutics 20021201
Pharmacological evidence of a role for prejunctional imidazoline (I(1)) receptors in ocular function.	Current eye research 20021101
[Obesity and hypertension. A dangerous liaison].	MMW Fortschritte der Medizin 20021024
Characterization of sucrose-induced changes in cardiac phenotype.	Pflugers Archiv : European journal of physiology 20021001
Pertussis toxin converts hyperpolarizations caused by alpha(2)-adrenoceptor agonists containing an imidazoline moiety into depolarizations in MIN 6 cells.	Naunyn-Schmiedeberg's archives of pharmacology 20020901
Restored capillary density in spared myocardium of infarcted rats improves ischemic tolerance.	Journal of cardiovascular pharmacology 20020901
Chronic imidazoline receptor activation in spontaneously hypertensive rats.	American journal of hypertension 20020901
Quinidine does not affect the renal clearance of moxonidine.	British journal of clinical pharmacology 20020901
Naphazoline-induced neuroendocrine changes: increases in ANP and cGMP levels, but suppression of NE, 3H-NE, and cAMP levels in rabbit eyes.	Pharmacology 20020701
[125I]2-(2-chloro-4-iodo-phenylamino)-5-methyl-pyrroline (LNP 911), a high-affinity radioligand selective for I1 imidazoline receptors.	Molecular pharmacology 20020701
[Conformational study of drugs which affect I1-imidazoline receptors].	Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020701
Imidazoline receptors in the heart: characterization, distribution, and regulation.	Journal of cardiovascular pharmacology 20020601
Contractile responses of the rat vas deferens after epithelium removal.	Life sciences 20020503
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.	The Journal of biological chemistry 20020419
The 'unsympathetic' nervous system of heart failure.	Circulation 20020416
Effects of sustained-release moxonidine, an imidazoline agonist, on plasma norepinephrine in patients with chronic heart failure.	Circulation 20020416
[Assessment of the effects of antihypertensive drugs on stress-induced cardiovascular changes].	Annales de cardiologie et d'angeiologie 20020401
Down-regulation of platelet imidazoline-1-binding sites after bupropion treatment.	The international journal of neuropsychopharmacology 20020301
[Moxonidine for hypertension. 'A good base for combination therapy'].	MMW Fortschritte der Medizin 20020124
alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy.	The Journal of pharmacology and experimental therapeutics 20020101
Identification, synthesis and pharmacological activity of moxonidine metabolites.	European journal of medicinal chemistry 20020101
Imidazoline antihypertensive drugs: a critical review on their mechanism of action.	Pharmacology & therapeutics 20020101
[Influence of long-term moxonidine (psysiotens) monotherapy on neuropsychological status and brain perfusion in elderly patients with arterial hypertension].	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101
Effects of central sympathetic inhibition on heart rate variability during steady-state exercise in healthy humans.	Clinical physiology and functional imaging 20020101
Placebo-controlled comparison of the efficacy and tolerability of once-daily moxonidine and enalapril in mild to moderate essential hypertension.	Blood pressure 20020101
Determination and quantification of clonidine in human blood serum.	Journal of biochemical and biophysical methods 20020101
[Policy of antihypertensive therapy in arterial hypertension in the elderly. II].	Klinicheskaia meditsina 20020101
Role of alpha 2-adrenoceptors and imidazoline receptors in the A5 region in the regulation of renal function in the rat.	Proceedings of the Western Pharmacology Society 20020101
[Pathogenetic role of moxonidine in the treatment of hypertension in postmenopausal women].	Kardiologiia 20020101
[Moxomidine effectiveness in women with arterial hypertension associated with metabolic syndrome in initially high heart rate].	Kardiologiia 20020101
[Clinical assessment of prolonged therapy of patients with hypertension and diabetes with imidazoline receptor agonist moxonidine].	Kardiologiia 20020101
The I1-imidazoline receptor in PC12 pheochromocytoma cells activates protein kinases C, extracellular signal-regulated kinase (ERK) and c-jun N-terminal kinase (JNK).	Journal of neurochemistry 20011201
Site of action of moxonidine in the rat nephron.	Naunyn-Schmiedeberg's archives of pharmacology 20011201
[Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation].	Zeitschrift fur Kardiologie 20011201
Role of the rostroventrolateral medulla in moxonidine-induced changes in cardiochronotropic regulation.	Bulletin of experimental biology and medicine 20011101
Alpha(2) receptors and agonists in pain management.	Current opinion in anaesthesiology 20011001
Effects of imidazoline antihypertensive drugs on sympathetic tone and noradrenaline release in the prefrontal cortex.	British journal of pharmacology 20010901
[The alpha 2-adrenergic receptors: molecular structure and in vivo function].	Zeitschrift fur Kardiologie 20010901
Moxonidine reduces pilocarpine-induced salivation in rats.	Autonomic neuroscience : basic & clinical 20010813
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failure.	International journal of cardiology 20010801
Safety and efficacy of moxonidine in mild to moderate hypertension.	The Journal of the Association of Physicians of India 20010801
Agmatine and putrescine uptake in the human glioma cell line SK-MG-1.	Naunyn-Schmiedeberg's archives of pharmacology 20010601
Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter.	Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601
[Treatment of hypertension in obesity].	Herz 20010501
Central imidazoline (I(1)) receptors modulate aqueous hydrodynamics.	Current eye research 20010501
Blockade by agmatine of catecholamine release from chromaffin cells is unrelated to imidazoline receptors.	European journal of pharmacology 20010406
Role of I(1)-imidazoline receptors and alpha2-adrenoceptors in hemodynamic effects of moxonidine administration into the rostroventrolateral medulla.	Bulletin of experimental biology and medicine 20010401
[Comparison of the antihypertensive efficacy of and tolerance to 2 imidazoline receptor agonists: moxonidine and rilmenidine in monotherapy].	Annales de cardiologie et d'angeiologie 20010401
Lowering of microalbuminuria in diabetic patients by a sympathicoplegic agent: novel approach to prevent progression of diabetic nephropathy?	Journal of the American Society of Nephrology : JASN 20010301
Interactions of ligands at angiotensin II-receptors and imidazoline receptors.	Japanese journal of pharmacology 20010201
Moxonidine: some controversy.	Expert opinion on pharmacotherapy 20010201
Pharmacodynamic models for the cardiovascular effects of moxonidine in patients with congestive heart failure.	British journal of clinical pharmacology 20010101
[Results of experimental and clinical trials of moxonidine presented at the 8th-10th European Hypertension Conferences].	Klinicheskaia meditsina 20010101
[Effect of moxonidine on the cardiac chronotropic regulation in hypertensive rats SHR-SP].	Eksperimental'naia i klinicheskaia farmakologiia 20010101
[Use of phisiotens for the treatment of arterial hypertension in elderly patients].	Terapevticheskii arkhiv 20010101
[ACE-dependent and sympathetic components of blood pressure regulation in patients with essential hypertension].	Voprosy meditsinskoi khimii 20010101
[Participation of central and peripheral I1-imidazollinovykh and alpha2-adrenergic receptors in realizing the effects of moxonidine].	Eksperimental'naia i klinicheskaia farmakologiia 20010101
[Imidazoline receptors-normal and pathological factors].	Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20010101
Centrally acting imidazoline I1-receptor agonists: do they have a place in the management of hypertension?	American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101
I1 imidazoline agonists. General clinical pharmacology of imidazoline receptors: implications for the treatment of the elderly.	Drugs & aging 20000801
Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild-type and D79N alpha2A-adrenoceptor transgenic mice.	British journal of pharmacology 19990301
[Cardiology in 1997].	Casopis lekaru ceskych 19981005
Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent.	Journal of human hypertension 19970801
Drug withdrawal and rebound hypertension: differential action of the central antihypertensive drugs moxonidine and clonidine.	Cardiovascular drugs and therapy 19960601
A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonist.	Cardiovascular drugs and therapy 19940301
Twenty-four-hour blood pressure profiles in patients with mild-to-moderate hypertension: moxonidine versus captopril.	Journal of cardiovascular pharmacology 19940101
Comparison of moxonidine and clonidine HCl in treating patients with hypertension.	Journal of clinical pharmacology 19870101

Moxonidine-induced priapism in an autosomal-dominant polycystic kidney disease dialysis patient.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120501

Moxonidine into the lateral parabrachial nucleus reduces renal and hormonal responses to cell dehydration.

Neuroscience 20120419

Crosstalk between central pathways of nitric oxide and carbon monoxide in the hypertensive action of cyclosporine.

Neuropharmacology 20120301

Development and validation of reversed phase high performance liquid chromatographic method for determination of moxonidine in the presence of its impurities.

Journal of pharmaceutical and biomedical analysis 20120205

Effects of imidazolines on neurogenic contraction in isolated urinary bladder detrusor strips from rabbit.

Canadian journal of physiology and pharmacology 20120201

Sympathoexcitation by brain oxidative stress mediates arterial pressure elevation in salt-induced chronic kidney disease.

Hypertension (Dallas, Tex. : 1979) 20120101

How full is our antihypertensives pipeline?

Journal of pharmacology & pharmacotherapeutics 20120101

An 'I' on cardiac hypertrophic remodelling: imidazoline receptors and heart disease.

The Canadian journal of cardiology 20120101

Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.

PloS one 20120101

Morphine and clonidine synergize to ameliorate low back pain in mice.

Pain research and treatment 20120101

Sympatho-renal axis in chronic disease.

Clinical research in cardiology : official journal of the German Cardiac Society 20111201

Changes in taste reactivity to intra-oral hypertonic NaCl after lateral parabrachial injections of an α2-adrenergic receptor agonist.

Physiology & behavior 20111024

α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.

Biological psychiatry 20111015

Moxonidine improves cardiac structure and performance in SHR through inhibition of cytokines, p38 MAPK and Akt.

British journal of pharmacology 20111001

Percutaneous renal denervation for the treatment of resistant essential hypertension; the first Dutch experience.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110801

Pecularities of prolonged use of moxonidine in patients with hypertension associated with metabolic syndrome.

Bulletin of experimental biology and medicine 20110801

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal of medicinal chemistry 20110714

Modulation of N-type Ca²⁺ currents by moxonidine via imidazoline I₁ receptor activation in rat superior cervical ganglion neurons.

Biochemical and biophysical research communications 20110617

Scintigraphic diagnosis of Erdheim-Chester disease.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601

[The efficacy and safety of moxonidine in patients with metabolic syndrome (the O.B.E.Z.I.T.A. trial)].

Vnitrni lekarstvi 20110601

Functional and molecular effects of imidazoline receptor activation in heart failure.

Life sciences 20110314

GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidine.

Cardiovascular research 20110201

High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy.

PloS one 20110101

Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism.

PloS one 20110101

PKreport: report generation for checking population pharmacokinetic model assumptions.

BMC medical informatics and decision making 20110101

[Possibilities of the use of moxonidine in the treatment of arterial hypertension in patients with metabolic syndrome and diabetes].

Kardiologiia 20110101

[Acute management at the rising of arterial pressure which is not menacing to a life].

Kardiologiia 20110101

Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain.

Journal of pain research 20110101

Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.

The open cardiovascular medicine journal 20110101

The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat.

International journal of nephrology 20110101

[Analysis of efficacy and safety of administration of moxonidine in patients with arterial hypertension and hypertensive crises].

Kardiologiia 20110101

Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients.

Journal of cardiovascular disease research 20110101

Estrogen receptor alpha expression in podocytes mediates protection against apoptosis in-vitro and in-vivo.

PloS one 20110101

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Effects of moxonidine on sympathetic nerve activity in patients with end-stage renal disease.

Journal of hypertension 20100901

Acute effects of moxonidine on cardiac autonomic modulation.

Pacing and clinical electrophysiology : PACE 20100801

A model of hypertension and proteinuria in cancer patients treated with the anti-angiogenic drug E7080.

Journal of pharmacokinetics and pharmacodynamics 20100801

Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats.

European journal of pharmacology 20100710

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.

Human molecular genetics 20100601

Successful treatment of cold-induced sweating in Crisponi syndrome and its possible mechanism of action.

Developmental medicine and child neurology 20100501

Effect of moxonidine and amlodipine on serum YKL-40, plasma lipids and insulin sensitivity in insulin-resistant hypertensive patients-a randomized, crossover trial.

Hypertension research : official journal of the Japanese Society of Hypertension 20100401

Microvascular effects of centrally acting antihypertensive drugs in spontaneously hypertensive rats.

Journal of cardiovascular pharmacology 20100301

[Combination therapy of hypertension in general clinical practice. The results of the KOHYBA study].

Vnitrni lekarstvi 20100301

Lateral parabrachial nucleus and central amygdala in the control of sodium intake.

Neuroscience 20100203

Comparable renovascular protective effects of moxonidine and simvastatin in rats exposed to cigarette smoke.

Vascular pharmacology 20100101

Experimental models of renal disease and the cardiovascular system.

The open cardiovascular medicine journal 20100101

Anorexia nervosa depends on adrenal sympathetic hyperactivity: opposite neuroautonomic profile of hyperinsulinism syndrome.

Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

Critical appraisal of the differential effects of antihypertensive agents on arterial stiffness.

Integrated blood pressure control 20100101

Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins.

Neurochemistry international 20091201

Adrenergic mechanisms of the Kölliker-Fuse/A7 area on the control of water and sodium intake.

Neuroscience 20091201

Rare psychotropic adverse event of moxonidine.

Psychiatria Danubina 20091201

Low dose of moxonidine within the rostral ventrolateral medulla improves the baroreflex sensitivity control of sympathetic activity in hypertensive rat.

Acta pharmacologica Sinica 20091201

Sympathoinhibitory mechanism of moxonidine: role of the inducible nitric oxide synthase in the rostral ventrolateral medulla.

Cardiovascular research 20091101

Facilitation of central imidazoline I(1)-site/extracellular signal-regulated kinase/p38 mitogen-activated protein kinase signalling mediates the hypotensive effect of ethanol in rats with acute renal failure.

British journal of pharmacology 20091101

Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.

The Biochemical journal 20091023

Pharmacological characterization of the inhibition by moxonidine and agmatine on the cardioaccelerator sympathetic outflow in pithed rats.

European journal of pharmacology 20090815

Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis.

Pharmacology & therapeutics 20090801

Comparison of agmatine with moxonidine and rilmenidine in morphine dependence in vitro: role of imidazoline I(1) receptors.

European journal of pharmacology 20090610

Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) 20090501

A preliminary report on the prognostic significance of preoperative brain natriuretic peptide and postoperative cardiac troponin in patients undergoing major vascular surgery.

Anesthesia and analgesia 20090401

Involvement of central alpha1-adrenoceptors on renal responses to central moxonidine and alpha-methylnoradrenaline.

European journal of pharmacology 20090401

Effect of moxonidine on the uveoscleral outflow: role of alpha2-adrenoceptors or i1 imidazoline receptors.

Current eye research 20090401

Testing conception of engagement of imidazoline receptors in imidazoline drugs effects on isolated rat heart atria.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301

Activation of alpha(2)-adrenoceptors in the lateral hypothalamus reduces pilocarpine-induced salivation in rats.

Neuroscience letters 20090206

Moxonidine prevents ischemia/reperfusion-induced renal injury in rats.

European journal of pharmacology 20090128

Interruption of central neuronal pathway of imidazoline I1 receptor mediates the hypertensive effect of cyclosporine in rats.

Brain research 20090112

Solvay addresses unmet needs in the management of hypertensive patients with cardiometabolic and lipid disorders.

Cardiovascular journal of Africa 20090101

Generation and characterization of novel human IRAS monoclonal antibodies.

Journal of biomedicine & biotechnology 20090101

Drugs associated with more suicidal ideations are also associated with more suicide attempts.

PloS one 20090101

An immunocompetent patient presenting with severe septic arthritis due to Ralstonia pickettii identified by molecular-based assays: a case report.

Cases journal 20090101

Protection in glutamate-induced neurotoxicity by imidazoline receptor agonist moxonidine.

The International journal of neuroscience 20090101

Implication of enterohepatic re-circulation on single dose bioequivalence evaluation of two brands of clonidine hydrochloride tablets in healthy human volunteers.

Indian journal of pharmaceutical sciences 20090101

Evidence that some imidazoline derivatives inhibit peripherally the vasopressor sympathetic outflow in pithed rats.

Autonomic neuroscience : basic & clinical 20081205

Addressing the relationship between sympathetic activity and inflammation.

Journal of hypertension 20081201

Central sympatholytic therapy has anti-inflammatory properties in hypertensive postmenopausal women.

Journal of hypertension 20081201

Biphasic dose-dependent modulation of cardiac parasympathetic activity by moxonidine, an imidazoline I1-receptor agonist.

Journal of cardiovascular pharmacology 20081201

Acute poisoning with moxonidine? A case report.

Clinical toxicology (Philadelphia, Pa.) 20081101

American College of Endocrinology Pre-Diabetes Consensus Conference: part two.

Diabetes care 20081101

[Arterial hypertension - dosing recommendations at beginning and end of treatment].

Therapeutische Umschau. Revue therapeutique 20081001

Clinical profile of eprosartan: a different angiotensin II receptor blocker.

Cardiovascular & hematological agents in medicinal chemistry 20081001

Principles for different modes of multiple-injection CZE.

Electrophoresis 20081001

Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation.

Current neuropharmacology 20080901

Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.

Current neuropharmacology 20080901

QSAR study of imidazoline antihypertensive drugs.

Bioorganic & medicinal chemistry 20080801

Potentiation by yohimbine of alpha-adrenoceptor-mediated vasoconstriction in response to clonidine in the rabbit ear vein.

European journal of pharmacology 20080728

Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease.

European journal of pharmacology 20080728

Effects of spinal alpha(2)-adrenoceptor and I(1)-imidazoline receptor activation on hindlimb movement induction in spinal cord-injured mice.

The Journal of pharmacology and experimental therapeutics 20080601

Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation.

British journal of pharmacology 20080201

Effects of sympatholytic therapy with moxonidine on serum adiponectin levels in hypertensive women.

The Journal of international medical research 20080101

[Effect of antihypertensive agents from various pharmacological groups on blood pressure reaction during stress-testing. Part I. Comparative characteristics of medications, exerting effect of sympathoadrenal block].

Kardiologiia 20080101

[The efficiency of combinations of Enalapril and long-acting Nifedipin and Moxonidine in patients with arterial hypertension and a metabolic syndrome].

Klinicheskaia meditsina 20080101

[The influence of antihypertensive agents on plasmatic and vascular-thrombocytic homeostasis in metabolic syndrome].

Eksperimental'naia i klinicheskaia farmakologiia 20080101

S1P-receptors in PC12 and transfected HEK293 cells: molecular targets of hypotensive imidazoline I(1) receptor ligands.

Neurochemistry international 20071201

Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method.

Pharmaceutical research 20071201

Randomized clinical trial of moxonidine in patients undergoing major vascular surgery.

The British journal of surgery 20071201

Peroxynitrite is Involved in the dysfunction of vasorelaxation in SHR/NDmcr-cp rats, spontaneously hypertensive obese rats.

Journal of cardiovascular pharmacology 20071201

Enhancement of meal-associated hypertonic NaCl intake by moxonidine into the lateral parabrachial nucleus.

Behavioural brain research 20071102

Sympathoexcitation of moxonidine in the caudal ventrolateral medulla is dependent on I1-imidazoline receptors in anesthetized rats.

Neuroscience letters 20071016

Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies.

Journal of pharmacokinetics and pharmacodynamics 20071001

Clonidine, moxonidine, folic acid, and mecobalamin improve baroreflex function in stroke-prone, spontaneously hypertensive rats.

Acta pharmacologica Sinica 20071001

Comparative study of NMDA and AMPA/kainate receptors involved in cardiovascular inhibition produced by imidazoline-like drugs in anaesthetized rats.

Experimental physiology 20070901

Effects of sympatholytic therapy on insulin sensitivity indices in hypertensive postmenopausal women.

International journal of clinical pharmacology and therapeutics 20070701

Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test.

European journal of pharmacology 20070622

Involvement of central alpha1- and alpha2-adrenoceptors on cardiovascular responses to moxonidine.

European journal of pharmacology 20070601

Centrally acting antihypertensive agents: an update.

Journal of clinical hypertension (Greenwich, Conn.) 20070501

Identification of IRAS/Nischarin as an I1-imidazoline receptor in PC12 rat pheochromocytoma cells.

Journal of neurochemistry 20070401

Metabolic and antihypertensive effects of moxonidine and moxonidine plus irbesartan in patients with type 2 diabetes mellitus and mild hypertension: a sequential, randomized, double-blind clinical trial.

Clinical therapeutics 20070401

Marked insulin resistance in obese spontaneously hypertensive rat adipocytes is ameliorated by in vivo but not in vitro treatment with moxonidine.

The Journal of pharmacology and experimental therapeutics 20070201

Adjunctive treatment with moxonidine versus nitrendipine for hypertensive patients with advanced renal failure: a cost-effectiveness analysis.

BMC nephrology 20070101

Moxonidine improves glycaemic control in mildly hypertensive, overweight type 2 diabetic patients.

Cardiovascular journal of Africa 20070101

[Arterial hypertension in extreme situations].

Klinicheskaia meditsina 20070101

Characterization of an antiproliferative effect of imidazoline receptor ligands on PC12 cells.

Pharmacological reports : PR 20070101

Alpha2-adrenergic activation in the lateral parabrachial nucleus induces NaCl intake under conditions of systemic hyperosmolarity.

Neuroscience 20060929

Involvement of phosphatidylcholine-selective phospholipase C in activation of mitogen-activated protein kinase pathways in imidazoline receptor antisera-selected protein.

Journal of cellular biochemistry 20060815

Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.

European journal of pharmacology 20060710

Moxonidine improves glycaemic control in mildly hypertensive, overweight patients: a comparison with metformin.

Diabetes, obesity & metabolism 20060701

Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide.

Journal of cardiovascular pharmacology 20060601

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Selective imidazoline agonist moxonidine in obese hypertensive patients.

International journal of clinical practice 20060501

[The modulatory influence of moxonidine on the different link of sympatho-adrenal system and hemodynamic reactions in normo and hypertensive rats during emotional stress].

Georgian medical news 20060401

Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.

Bioorganic & medicinal chemistry 20060315

Influence of central inhibition of sympathetic nervous activity on myocardial metabolism in chronic heart failure: acute effects of the imidazoline I1-receptor agonist moxonidine.

Clinical science (London, England : 1979) 20060301

Effects of eprosartan on target organ protection.

Vascular health and risk management 20060301

Presynaptic I1-imidazoline receptors reduce GABAergic synaptic transmission in striatal medium spiny neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208

Determination of moxonidine in human plasma by liquid chromatography-electrospray ionisation-mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20060123

Insulin resistance and sympathetic overactivity in women.

Journal of hypertension 20060101

Cause and consequences of sympathetic hyperactivity in chronic kidney disease.

Blood purification 20060101

Lipid-lowering actions of imidazoline antihypertensive agents in metabolic syndrome X.

Naunyn-Schmiedeberg's archives of pharmacology 20060101

Moxonidine: a review of its use in essential hypertension.

Drugs 20060101

[Comparison of the effectiveness of moxonidine and prestarium in postmenopausal women with mild and moderate arterial hypertension].

Klinicheskaia meditsina 20060101

[The use of moxonidine in women with arterial hypertension in postmenopausal period].

Kardiologiia 20060101

Centrally acting imidazolines stimulate vascular alpha 1A-adrenergic receptors in Rat-Tail Artery.

Cellular and molecular neurobiology 20060101

Moxonidine well tolerated and effective in the treatment of viscerally obese, non-controlled hypertensive patients.

Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101

The effect of moxonidine on endothelial dysfunction in metabolic syndrome.

American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

Imidazoline receptors in relaxation of acetylcholine-constricted isolated rat jejunum.

Pharmacological reports : PR 20060101

Identification of the central imidazoline receptor subtype involved in modulation of halothane-epinephrine arrhythmias in rats.

Anesthesia and analgesia 20051201

Use of moxonidine in elderly patients with resistant hypertension.

Journal of clinical pharmacy and therapeutics 20051001

[Antihypertensive therapy and drug-drug interactions].

Revue medicale suisse 20050914

Urinary responses to acute moxonidine are inhibited by natriuretic peptide receptor antagonist.

British journal of pharmacology 20050501

Non-adrenergic inhibition at prejunctional sites by agmatine of purinergic vasoconstriction in rabbit saphenous artery.

Neuropharmacology 20050301

Efficacy of moxonidine in the treatment of hypertension in obese, noncontrolled hypertensive patients.

Kidney international. Supplement 20050101

Application of population pharmacokinetics to cladribine.

BMC pharmacology 20050101

[Clinicogenetic aspects of carbohydrate metabolism disorders and efficacy of their correction with moxonidine and metformine in patients with arterial hypertension].

Terapevticheskii arkhiv 20050101

[The role of alpha2-adrenergic and I1-imidazoline receptors in the effects of clonidine and moxonidine on isolated large intestine of mice].

Eksperimental'naia i klinicheskaia farmakologiia 20050101

Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine.

Neuroscience 20050101

Moxonidine suitable for hypertensive menopausal women with metabolic syndrome.

Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

Cardiovascular and survival effects of sympatho-inhibitors in adriamycin-induced cardiomyopathy in rats.

Fundamental & clinical pharmacology 20041201

Different effects of losartan and moxonidine on endothelial function during sympathetic activation in essential hypertension.

Journal of clinical hypertension (Greenwich, Conn.) 20041201

Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.

Journal of the American Society of Nephrology : JASN 20041101

The data monitoring experience in the MOXCON trial.

European heart journal 20041101

New pharmacological strategies in chronic heart failure.

Cardiovascular drugs and therapy 20041101

Modulation of gene expression by moxonidine in rats with chronic renal failure.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901

Moxonidine in the treatment of overweight and obese patients with the metabolic syndrome: a postmarketing surveillance study.

Journal of human hypertension 20040901

Imidazoline receptors but not alpha 2-adrenoceptors are regulated in spontaneously hypertensive rat heart by chronic moxonidine treatment.

The Journal of pharmacology and experimental therapeutics 20040801

Imidazoline receptors in the heart: a novel target and a novel mechanism of action that involves atrial natriuretic peptides.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040801

Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy.

American journal of physiology. Heart and circulatory physiology 20040701

Increased infarct size in uremic rats: reduced ischemia tolerance?

Journal of the American Society of Nephrology : JASN 20040601

Central blockade of nitric oxide synthesis reduces moxonidine-induced hypotension.

British journal of pharmacology 20040601

Effects of moxonidine vs. metoprolol on blood pressure and metabolic control in hypertensive subjects with type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040601

Moxonidine and rilmenidine injected into the medial septal area reduces the salivation induced by pilocarpine.

Autonomic neuroscience : basic & clinical 20040531

Effect of i1 imidazoline receptor agonist, moxonidine, in nitric oxide-deficient hypertension in pregnant rats.

Journal of cardiovascular pharmacology 20040501

The I1-imidazoline agonist moxonidine decreases sympathetic tone under physical and mental stress.

British journal of clinical pharmacology 20040501

Effect of moxonidine on lipid subfractions in patients with hypertension.

International journal of clinical practice 20040501

Selective imidazoline agonist moxonidine plus the ACE inhibitor ramipril in hypertensive patients with impaired insulin sensitivity: partners in a successful MARRIAGE?

Current medical research and opinion 20040301

The metabolic syndrome in women: implications for therapy.

International journal of clinical practice. Supplement 20040301

Treatment of postmenopausal hypertension with moxonidine, a selective imidazoline receptor agonist.

International journal of clinical practice. Supplement 20040301

Effect of moxonidine on contractile activity of isolated large intestine in mice: role of alpha2-adrenoceptors and Ii-imidazoline receptors.

Bulletin of experimental biology and medicine 20040301

Pharmacological therapy can increase capillary density in post-infarction remodeled rat hearts.

Cardiovascular research 20040215

Moxonidine, an antihypertensive agent, is permissive to alpha1-adrenergic receptor pathway in the rat-tail artery.

Journal of cardiovascular pharmacology 20040201

The effects of imidazoline agents on the aggregation of human platelets.

The Journal of pharmacy and pharmacology 20040201

Elevated sympathetic activity may promote insulin resistance syndrome by activating alpha-1 adrenergic receptors on adipocytes.

Medical hypotheses 20040101

Effect of moxonidine on putative sympathetic neurons in the rostral ventrolateral medulla of the rat.

Neuro-Signals 20040101

[Effect of moxonidine on parameters of lipid metabolism in patients with metabolic syndrome.].

Kardiologiia 20040101

Activation of alpha2-adrenergic receptors into the lateral parabrachial nucleus enhances NaCl intake in rats.

Neuroscience 20040101

[The role of hypersympathycotony in development of arterial hypertension in patients with metabolic syndrome: potential of pathogenetically sound therapy].

Terapevticheskii arkhiv 20040101

Moxonidine and central alpha2 adrenergic receptors in sodium intake.

Brain research 20031212

Contrasting metabolic effects of antihypertensive agents.

The Journal of pharmacology and experimental therapeutics 20031201

Electrophysiological responses to imidazoline/alpha2-receptor agonists in rabbit sinoatrial node pacemaker cells.

Acta pharmacologica Sinica 20031201

Identification and pharmacological characterization of a specific agmatine transport system in human tumor cell lines.