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75330-75-5 | Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-
CAS No: 75330-75-5 Catalog No: AG005C7G MDL No:MFCD00072164
Product Description
Catalog Number:
AG005C7G
Chemical Name:
Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-
CAS Number:
75330-75-5
Molecular Formula:
C24H36O5
Molecular Weight:
404.5396
MDL Number:
MFCD00072164
IUPAC Name:
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
InChI:
InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI Key:
PCZOHLXUXFIOCF-BXMDZJJMSA-N
SMILES:
CC[C@@H](C(=O)O[C@H]1C[C@@H](C)C=C2[C@H]1[C@@H](CC[C@@H]1C[C@@H](O)CC(=O)O1)[C@H](C=C2)C)C
EC Number:
616-212-7
UNII:
9LHU78OQFD
Properties
Complexity:
666
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
8
Defined Bond Stereocenter Count:
0
Exact Mass:
404.256g/mol
Formal Charge:
0
Heavy Atom Count:
29
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
404.547g/mol
Monoisotopic Mass:
404.256g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
72.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.3
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| Effect of hydroalcoholic extract of Hypericum perforatum on selected traditional and novel biochemical factors of cardiovascular diseases and atherosclerotic lesions in hypercholesterolemic rabbits: A comparison between the extract and lovastatin. | Journal of pharmacy & bioallied sciences 20120101 |
| Effects of tocotrienol and lovastatin combination on osteoblast and osteoclast activity in estrogen-deficient osteoporosis. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class. | PloS one 20120101 |
| Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy. | PloS one 20120101 |
| Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells. | PloS one 20120101 |
| Transgelin 2 participates in lovastatin-induced anti-angiogenic effects in endothelial cells through a phosphorylated myosin light chain-related mechanism. | PloS one 20120101 |
| Regulatory cross talk and microbial induction of fungal secondary metabolite gene clusters. | Methods in enzymology 20120101 |
| Lovastatin production by Aspergillus terreus using agro-biomass as substrate in solid state fermentation. | Journal of biomedicine & biotechnology 20120101 |
| Quantitative proteomic analysis revealed lovastatin-induced perturbation of cellular pathways in HL-60 cells. | Journal of proteome research 20111202 |
| CKD-MBD after kidney transplantation. | Pediatric nephrology (Berlin, Germany) 20111201 |
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| Therapeutics for childhood neurofibromatosis type 1 and type 2. | Current treatment options in neurology 20111201 |
| Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol. | Journal of neurochemistry 20111201 |
| Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. | Biochemical pharmacology 20111201 |
| Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy. | Apoptosis : an international journal on programmed cell death 20111201 |
| Preparation and characterization of a lovastatin-loaded protein-free nanostructured lipid carrier resembling high-density lipoprotein and evaluation of its targeting to foam cells. | AAPS PharmSciTech 20111201 |
| Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. | Molecular nutrition & food research 20111201 |
| Valosin-containing protein and neurofibromin interact to regulate dendritic spine density. | The Journal of clinical investigation 20111201 |
| Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin. | Journal of Korean medical science 20111201 |
| Floral odor bouquet loses its ant repellent properties after inhibition of terpene biosynthesis. | Journal of chemical ecology 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. | Oncotarget 20111201 |
| Recent advances in mechanisms and treatments of airway remodeling in asthma: a message from the bench side to the clinic. | The Korean journal of internal medicine 20111201 |
| Prediction of drug combinations by integrating molecular and pharmacological data. | PLoS computational biology 20111201 |
| [Red yeast rice can lower cholesterol but should not replace established therapy]. | Lakartidningen 20111201 |
| [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study]. | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201 |
| Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents. | Bioorganic & medicinal chemistry letters 20111115 |
| Phylogeny of Penicillium and the segregation of Trichocomaceae into three families. | Studies in mycology 20111115 |
| Cost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108 |
| Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism. | The Journal of investigative dermatology 20111101 |
| Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells. | Pflugers Archiv : European journal of physiology 20111101 |
| Statins inhibit iNOS-mediated microbicidal potential of activated monocyte-derived dendritic cells by an IFN-β-dependent mechanism. | European journal of immunology 20111101 |
| A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro. | Journal of lipid research 20111101 |
| Efficient bioconversion of compactin to pravastatin by the quinoline-degrading microorganism Pseudonocardia carboxydivorans isolated from petroleum-contaminated soil. | Bioresource technology 20111101 |
| Statin effects on regulatory and proinflammatory factors in chronic idiopathic urticaria. | Clinical and experimental immunology 20111101 |
| A cost-benefit analysis of lipid standardization in the United States. | Preventing chronic disease 20111101 |
| Modifiers of symptomatic embolic risk in infective endocarditis. | Mayo Clinic proceedings 20111101 |
| Preparation of lovastatin matrix sustained-release pellets by extrusion-spheronization combined with microcrystal dispersion technique. | Archives of pharmacal research 20111101 |
| Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I. | Human molecular genetics 20111015 |
| Highly efficient release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles enhances bone repair in rats. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20111001 |
| Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis. | Lipids 20111001 |
| Thalidomide, dexamethasone and lovastatin with autologous stem cell transplantation as a salvage immunomodulatory therapy in patients with relapsed and refractory multiple myeloma. | Annals of hematology 20111001 |
| Induction of a high-yield lovastatin mutant of Aspergillus terreus by ¹²C⁶⁺ heavy-ion beam irradiation and the influence of culture conditions on lovastatin production under submerged fermentation. | Applied biochemistry and biotechnology 20111001 |
| Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts. | Biochimica et biophysica acta 20111001 |
| The cytostatic effects of lovastatin on ACC-MESO-1 cells. | The Journal of surgical research 20111001 |
| Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent. | European journal of medicinal chemistry 20111001 |
| Antioxidant effect of red mould rice in hypercholesterolemic Wistar male rats. | Cell biochemistry and function 20111001 |
| Lovastatin as treatment for neurocognitive deficits in neurofibromatosis type 1: phase I study. | Pediatric neurology 20111001 |
| Adverse drug reactions caused by drug-drug interactions reported to Croatian Agency for Medicinal Products and Medical Devices: a retrospective observational study. | Croatian medical journal 20111001 |
| [Rhabdomyolysis related to statin and seizures: report of 3 cases]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111001 |
| [Study on effect of berberine on modulating lipid and CPT I A gene expression]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111001 |
| Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation? | Archives of medical science : AMS 20111001 |
| Osteoprotective effect of Monascus-fermented dioscorea in ovariectomized rat model of postmenopausal osteoporosis. | Journal of agricultural and food chemistry 20110914 |
| The 2',4',6'-trihydroxyacetophenone isolated from Myrcia multiflora has antiobesity and mixed hypolipidemic effects with the reduction of lipid intestinal absorption. | Planta medica 20110901 |
| Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders. | Pharmacological research 20110901 |
| Beneficial effects of combinatorial micronutrition on body fat and atherosclerosis in mice. | Cardiovascular research 20110901 |
| AAPS workshop report: strategies to address therapeutic protein-drug interactions during clinical development. | The AAPS journal 20110901 |
| Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. | Journal of cellular physiology 20110901 |
| Xuezhikang, extract of red yeast rice, inhibited tissue factor and hypercoagulable state through suppressing nicotinamide adenine dinucleotide phosphate oxidase and extracellular signal-regulated kinase activation. | Journal of cardiovascular pharmacology 20110901 |
| Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients. | Annals of neurology 20110901 |
| Evaluation of a pharmacist-managed amiodarone monitoring program. | Journal of managed care pharmacy : JMCP 20110901 |
| Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. | PLoS pathogens 20110901 |
| The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. | PLoS genetics 20110901 |
| Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line. | European review for medical and pharmacological sciences 20110901 |
| [Clinical study on the treatment of abnormal blood lipids complicated with carotid atherosclerosis with lipid-reducing red rice minute powder: a randomized controlled trial]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110901 |
| Inhibition of endothelial adhesion molecule expression by Monascus purpureus-fermented rice metabolites, monacolin K, ankaflavin, and monascin. | Journal of the science of food and agriculture 20110815 |
| Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | The Biochemical journal 20110815 |
| Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. | The pharmacogenomics journal 20110801 |
| Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle. | Cell death and differentiation 20110801 |
| Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines. | Environmental and molecular mutagenesis 20110801 |
| Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells. | Endocrine-related cancer 20110801 |
| Parkinson's disease mouse models in translational research. | Mammalian genome : official journal of the International Mammalian Genome Society 20110801 |
| Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus. | Diabetologia 20110801 |
| Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation. | Endocrinology 20110801 |
| Juvenile toxicity assessment of open-acid lovastatin in rats. | Birth defects research. Part B, Developmental and reproductive toxicology 20110801 |
| Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts. | The Biochemical journal 20110801 |
| SR-PSOX at sites predisposed to atherosclerotic lesion formation mediates monocyte-endothelial cell adhesion. | Atherosclerosis 20110801 |
| Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity. | Cell death & disease 20110801 |
| Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection. | PLoS pathogens 20110801 |
| Diallyl disulphide and lovastatin: effects on energy and protein utilisation in, as well as methane emission from, sheep. | Archives of animal nutrition 20110801 |
| Comparison of different extraction methods for the determination of statin drugs in wastewater and river water by HPLC/Q-TOF-MS. | Talanta 20110715 |
| Rhadbomyolysis associated with co-administration of danazol and lovastatin. | British journal of clinical pharmacology 20110701 |
| The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency. | Pediatric research 20110701 |
| Use of transporter knockdown Caco-2 cells to investigate the in vitro efflux of statin drugs. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
| Antitumor effects of the combination of cholesterol reducing drugs. | Oncology reports 20110701 |
| Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec). | The British journal of nutrition 20110701 |
| Is there a treatment advantage when paclitaxel and lovastatin are combined to dose anaplastic thyroid carcinoma cell lines? | Thyroid : official journal of the American Thyroid Association 20110701 |
| Lovastatin and valproic acid additively attenuate cell invasion in ACC-MESO-1 cells. | Biochemical and biophysical research communications 20110701 |
| Trichothecenes: from simple to complex mycotoxins. | Toxins 20110701 |
| Antioxidant effects of Citrus aurantifolia (Christm) juice and peel extract on LDL oxidation. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701 |
| New species in Aspergillus section Terrei. | Studies in mycology 20110630 |
| [Pharmaco-economic optimization of cholesterol-lowering treatment with statins]. | Medicina clinica 20110625 |
| Polysorbates as novel lipid-modulating candidates for reducing serum total cholesterol and low-density lipoprotein levels in hyperlipidemic C57BL/6J mice and rats. | European journal of pharmacology 20110625 |
| Statins and prostate cancer diagnosis and grade in a veterans population. | Journal of the National Cancer Institute 20110608 |
| Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis. | The Journal of surgical research 20110601 |
| Mode of action of parasporin-4, a cytocidal protein from Bacillus thuringiensis. | Biochimica et biophysica acta 20110601 |
| A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus. | Fungal genetics and biology : FG & B 20110601 |
| Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse. | Drug metabolism and disposition: the biological fate of chemicals 20110601 |
| Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA. | Journal of the American Chemical Society 20110601 |
| Specific inhibitions of annonaceous acetogenins on class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae. | Bioorganic & medicinal chemistry 20110601 |
| Niacin extended-release therapy in phase III clinical trials is associated with relatively low rates of drug discontinuation due to flushing and treatment-related adverse events: a pooled analysis. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20110601 |
| Lovastatin causes diminished PSA secretion by inhibiting AR expression and function in LNCaP prostate cancer cells. | Urology 20110601 |
| Antihyperlipidemic activities of Pleurotus ferulae on biochemical and histological function in hypercholesterolemic rats. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110601 |
| [Experimental studies on blood lipid regulating effects of shuanghua granules]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601 |
| 2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
| Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells. | Cancer chemotherapy and pharmacology 20110501 |
| Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | The Journal of veterinary medical science 20110501 |
| Development of natural anti-tumor drugs by microorganisms. | Journal of bioscience and bioengineering 20110501 |
| Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate. | The Journal of pharmacology and experimental therapeutics 20110501 |
| Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. | Cancer letters 20110501 |
| Adherence to single-pill combination versus multiple-pill combination lipid-modifying therapy among patients with mixed dyslipidemia in a managed care population. | Current medical research and opinion 20110501 |
| Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. | The Journal of investigative dermatology 20110501 |
| Decrease in dipeptidyl peptidase IV activity is linked to the efficacy of differentiating compounds in follicular thyroid carcinoma cell lines. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110501 |
| Native low-density lipoprotein-dependent interleukin-8 production through pertussis toxin-sensitive G-protein coupled receptors and hydrogen peroxide generation contributes to migration of human aortic smooth muscle cells. | Yonsei medical journal 20110501 |
| Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | Experimental biology and medicine (Maywood, N.J.) 20110501 |
| Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients. | Korean circulation journal 20110501 |
| Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells. | Leukemia research 20110401 |
| Lovastatin promotes redifferentiation of human nucleus pulposus cells during expansion in monolayer culture. | Artificial organs 20110401 |
| The effect of lovastatin on oxidative stress and antioxidant enzymes in hydrogen peroxide intoxicated rat. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401 |
| Lactone form 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) stimulate the osteoblastic differentiation of mouse periodontal ligament cells via the ERK pathway. | Journal of periodontal research 20110401 |
| Simvastatin prevents skeletal metastasis of breast cancer by an antagonistic interplay between p53 and CD44. | The Journal of biological chemistry 20110401 |
| Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin. | The Journal of pharmacology and experimental therapeutics 20110401 |
| Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b. | Journal of leukocyte biology 20110401 |
| An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia. | Pediatric cardiology 20110401 |
| Chinese red yeast rice inhibition of prostate tumor growth in SCID mice. | Cancer prevention research (Philadelphia, Pa.) 20110401 |
| Arecoline stimulated Cyr61 production in human gingival epithelial cells: inhibition by lovastatin. | Oral oncology 20110401 |
| Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells. | Investigative ophthalmology & visual science 20110325 |
| Demographic determinants of response to statin medications. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110315 |
| Aspergillus as a multi-purpose cell factory: current status and perspectives. | Biotechnology letters 20110301 |
| Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110301 |
| Structure elucidation and complete NMR spectral assignment of an unusual aromatic monacolin analog from Monascus purpureus-fermented rice. | Magnetic resonance in chemistry : MRC 20110301 |
| Azathioprine-induced fever in sarcoidosis. | The Annals of pharmacotherapy 20110301 |
| Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy. | Iranian journal of kidney diseases 20110301 |
| Survival rates of early-stage HCV-related liver cirrhosis patients without hepatocellular carcinoma are decreased by alcohol. | Journal of clinical biochemistry and nutrition 20110301 |
| Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. | PLoS biology 20110301 |
| Depressogenic effects of medications: a review. | Dialogues in clinical neuroscience 20110301 |
| Thrombotic Thrombocytopenic Purpura associated with Clopidogrel: a case report and review of the literature. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110301 |
| C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study. | Lancet (London, England) 20110205 |
| Promotion of Monacolin K production by Agrobacterium tumefaciens-mediated transformation in Monascus albidus 9901. | Current microbiology 20110201 |
| Lovastatin enhances paraoxonase enzyme activity and quells low-density lipoprotein susceptibility to oxidation in type 2 diabetic nephropathy. | Clinical biochemistry 20110201 |
| Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP? | Current atherosclerosis reports 20110201 |
| Suppression of statin effectiveness by copper and zinc in yeast and human cells. | Molecular bioSystems 20110201 |
| What combination therapy with a statin, if any, would you recommend? | Current atherosclerosis reports 20110201 |
| OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling. | Atherosclerosis 20110201 |
| Orthopaedic aspects of neurofibromatosis: update. | Current opinion in pediatrics 20110201 |
| Novel extended-release formulation of lovastatin by one-step melt granulation: in vitro and in vivo evaluation. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110201 |
| Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection. | Current atherosclerosis reports 20110201 |
| Influence of one-year treatment with lovastatin on myocardial remodeling and ischemia in patients with coronary artery disease. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110201 |
| In vivo and in vitro anti-inflammatory and anti-nociceptive activities of lovastatin in rodents. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110201 |
| May lovastatin target both autism and epilepsy? A novel hypothesized treatment. | Epilepsy & behavior : E&B 20110201 |
| Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. | Diabetes 20110201 |
| Is red yeast rice safe and effective for lowering serum cholesterol? | Journal of the American Dietetic Association 20110201 |
| Lovastatin changes activities of lactate dehydrogenase A and B genes in rat myocardial cells. | Chinese medical journal 20110201 |
| Production of lovastatin by wild strains of Aspergillus terreus. | Natural product communications 20110201 |
| Letter: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67). | Diabetes & metabolism journal 20110201 |
| [Retention behavior of statins in microemulsion liquid chromatography]. | Se pu = Chinese journal of chromatography 20110201 |
| Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients. | Hepatitis monthly 20110201 |
| FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. | Biochemistry 20110118 |
| Development of biodegradable porous starch foam for improving oral delivery of poorly water soluble drugs. | International journal of pharmaceutics 20110117 |
| Lovastatin biosynthesis by Aspergillus terreus with the simultaneous use of lactose and glycerol in a discontinuous fed-batch culture. | Journal of biotechnology 20110110 |
| Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor. | Biochemical and biophysical research communications 20110107 |
| Medical therapy for advanced pancreatic cancer: work in progress. | JOP : Journal of the pancreas 20110105 |
| Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benz[a]anthracene-Induced Oral Carcinogenesis in Hamster. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Statins: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors demonstrate anti-atherosclerotic character due to their antioxidant capacity. | Applied biochemistry and biotechnology 20110101 |
| Effects of bile salts on the lovastatin pharmacokinetics following oral administration to rats. | Drug delivery 20110101 |
| Proteomics of industrial fungi: trends and insights for biotechnology. | Applied microbiology and biotechnology 20110101 |
| Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination. | Journal of biomedicine & biotechnology 20110101 |
| Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes. | Endocrinology 20110101 |
| Lovastatin decreases the synthesis of inflammatory mediators in the hippocampus and blocks the hyperthermia of rats submitted to long-lasting status epilepticus. | Epilepsy & behavior : E&B 20110101 |
| Statins have an early antiplatelet effect in patients with acute myocardial infarction. | Platelets 20110101 |
| Effect of hydroxymethylglutaryl-CoA reductase inhibitors on low-density lipoprotein cholesterol, interleukin-6, and high-sensitivity C-reactive protein in end-stage renal disease. | Iranian journal of kidney diseases 20110101 |
| Effects of lovastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats: possible role of cytochrome P450 3A4 and P-glycoprotein inhibition by lovastatin. | The Journal of pharmacy and pharmacology 20110101 |
| Transcription factors CgUPC2A and CgUPC2B regulate ergosterol biosynthetic genes in Candida glabrata. | Genes to cells : devoted to molecular & cellular mechanisms 20110101 |
| Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment. | Journal of Alzheimer's disease : JAD 20110101 |
| Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line. | Lipids in health and disease 20110101 |
| Statins reduce dengue virus production via decreased virion assembly. | Intervirology 20110101 |
| Cardiovascular prevention of cognitive decline. | Cardiology research and practice 20110101 |
| Restoration of cognitive deficits after statin feeding in TBI. | Restorative neurology and neuroscience 20110101 |
| Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits. | Vascular health and risk management 20110101 |
| Low density lipoprotein receptor gene Ava II polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. | Lipids in health and disease 20110101 |
| Low level bacterial endotoxin activates two distinct signaling pathways in human peripheral blood mononuclear cells. | Journal of inflammation (London, England) 20110101 |
| Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage. | Malaria journal 20110101 |
| δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens. | Lipids in health and disease 20110101 |
| Effect of atorvastatin and clopidogrel co-administration after coronary stenting in korean patients with stable angina. | Korean circulation journal 20110101 |
| Topical preparations for pain relief: efficacy and patient adherence. | Journal of pain research 20110101 |
| Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol. | PloS one 20110101 |
| The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals. | PloS one 20110101 |
| Synchronous high-performance liquid chromatography with a photodiode array detector and mass spectrometry for the determination of citrinin, monascin, ankaflavin, and the lactone and acid forms of monacolin K in red mold rice. | Journal of AOAC International 20110101 |
| Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris. | Cardiology research and practice 20110101 |
| Sex differences in drug disposition. | Journal of biomedicine & biotechnology 20110101 |
| Cell cycle-dependent induction of homologous recombination by a tightly regulated I-SceI fusion protein. | PloS one 20110101 |
| Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy. | Lipids in health and disease 20110101 |
| Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins. | International journal of hypertension 20110101 |
| Structure modeling and inhibitor prediction ofNADP oxidoreductase enzyme from Methanobrevibacter smithii. | Bioinformation 20110101 |
| Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes. | Core evidence 20110101 |
| Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly. | Clinical interventions in aging 20110101 |
| Elevated expression of CDK4 in lung cancer. | Journal of translational medicine 20110101 |
| NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells. | PloS one 20110101 |
| Hypolipidemic potential of ethanolic extract of Verbesina encelioides Benth. roots. | Acta poloniae pharmaceutica 20110101 |
| Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries. | Lipids in health and disease 20110101 |
| Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males. | PloS one 20110101 |
| Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes. | International journal of Alzheimer's disease 20110101 |
| Pleiotropic effects of the HMG-CoA reductase inhibitors. | International journal of general medicine 20110101 |
| Clinical use and effectiveness of lipid lowering therapies in diabetes mellitus--an observational study from the Swedish National Diabetes Register. | PloS one 20110101 |
| Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro. | BMC cancer 20110101 |
| Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. | PloS one 20110101 |
| Long-term use of fenofibrate is associated with increased prevalence of gallstone disease among patients undergoing maintenance hemodialysis. | Renal failure 20110101 |
| 'Humanized' stem cell culture techniques: the animal serum controversy. | Stem cells international 20110101 |
| Exogenous control of the expression of Group I CD1 molecules competent for presentation of microbial nonpeptide antigens to human T lymphocytes. | Clinical & developmental immunology 20110101 |
| Lipid lowering by hydroalcoholic extracts of Amaranthus caudatus L. induces regression of rabbits atherosclerotic lesions. | Lipids in health and disease 20110101 |
| Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells. | PloS one 20110101 |
| Exploring dietitians' salient beliefs about shared decision-making behaviors. | Implementation science : IS 20110101 |
| Orange juice and its component, hesperidin, decrease the expression of multidrug resistance-associated protein 2 in rat small intestine and liver. | Journal of biomedicine & biotechnology 20110101 |
| Manipulation of pH shift to enhance the growth and antibiotic activity of Xenorhabdus nematophila. | Journal of biomedicine & biotechnology 20110101 |
| Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART). | Lipids in health and disease 20110101 |
| Aliskiren: An orally active renin inhibitor. | Journal of pharmacy & bioallied sciences 20110101 |
| Tolvaptan, hyponatremia, and heart failure. | International journal of nephrology and renovascular disease 20110101 |
| The role of fatty aldehyde dehydrogenase in epidermal structure and function. | Dermato-endocrinology 20110101 |
| Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders. | Dermato-endocrinology 20110101 |
| The RNA editing pattern of cox2 mRNA is affected by point mutations in plant mitochondria. | PloS one 20110101 |
| Relationship between a novel polymorphism of the C5L2 gene and coronary artery disease. | PloS one 20110101 |
| Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors. | Pharmacology 20110101 |
| A comparative study of the pharmacokinetics of traditional and automated dosing/blood sampling systems using gabapentin. | Indian journal of pharmacology 20110101 |
| Association of statin therapy with blood pressure control in hypertensive hypercholesterolemic outpatients in clinical practice. | Journal of cardiovascular disease research 20110101 |
| Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma. | Chemistry Central journal 20110101 |
| Synchronization of HeLa cells. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Sensitivity to lovastatin of Saccharomyces cerevisiae strains deleted for pleiotropic drug resistance (PDR) genes. | Journal of molecular microbiology and biotechnology 20110101 |
| Stem cells for cardiac repair: status, mechanisms, and new strategies. | Stem cells international 20110101 |
| Treating statin-intolerant patients. | Diabetes, metabolic syndrome and obesity : targets and therapy 20110101 |
| Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study. | BMC cardiovascular disorders 20110101 |
| Antiatherogenic Potential of Nigella sativa Seeds and Oil in Diet-Induced Hypercholesterolemia in Rabbits. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| The roles of buyang huanwu decoction in anti-inflammation, antioxidation and regulation of lipid metabolism in rats with myocardial ischemia. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Depression in vascular pathologies: the neurologist's point of view. | Vascular health and risk management 20110101 |
| Morphology engineering--osmolality and its effect on Aspergillus niger morphology and productivity. | Microbial cell factories 20110101 |
| Deciphering the Actions of Antiparkinsonian and Antipsychotic Drugs on cAMP/DARPP-32 Signaling. | Frontiers in neuroanatomy 20110101 |
| Clopidogrel effectively suppresses endothelial microparticle generation induced by indoxyl sulfate via inhibition of the p38 mitogen-activated protein kinase pathway. | Blood purification 20110101 |
| Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101 |
| Ligation of macrophage Fcγ receptors recapitulates the gene expression pattern of vulnerable human carotid plaques. | PloS one 20110101 |
| Assessment of cholesterol homeostasis in astrocytes and neurons. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Lysophosphatidic acid and lovastatin might protect kidney in renal I/R injury by downregulating MCP-1 in rat. | Renal failure 20110101 |
| Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. | PloS one 20110101 |
| Simultaneous enrichment of deglycosylated ginsenosides and monacolin K in red ginseng by fermentation with Monascus pilosus. | Bioscience, biotechnology, and biochemistry 20110101 |
| Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells. | Journal of biomedical science 20110101 |
| Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | PloS one 20110101 |
| Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. | Journal of experimental & clinical cancer research : CR 20110101 |
| Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients. | Indian journal of pharmacology 20110101 |
| Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis. | Frontiers in pharmacology 20110101 |
| Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients. | Lipids in health and disease 20110101 |
| Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | Respiratory research 20110101 |
| Branch retinal vein occlusion associated with quetiapine fumarate. | BMC ophthalmology 20110101 |
| Treatment of allergic asthma: modulation of Th2 cells and their responses. | Respiratory research 20110101 |
| Treatment of an adrenomyeloneuropathy patient with Lorenzo's oil and supplementation with docosahexaenoic acid--a case report. | Lipids in health and disease 20110101 |
| Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation. | Frontiers in neuroanatomy 20110101 |
| Stepwise approach to myopathy in systemic disease. | Frontiers in neurology 20110101 |
| Synthesis, characterization and quantification of simvastatin metabolites and impurities. | Scientia pharmaceutica 20110101 |
| Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium. | Marine drugs 20110101 |
| Emerging therapies for severe asthma. | BMC medicine 20110101 |
| Formulation and evaluation of solid lipid nanoparticles of ramipril. | Journal of young pharmacists : JYP 20110101 |
| Remembering what's new in Alzheimer's management. | Journal of pharmacology & pharmacotherapeutics 20110101 |
| High Sensitivity C - Reactive Protein is Associated with Diastolic Dysfunction in Young African Americans without Clinically Evident Cardiac Disease. | The open cardiovascular medicine journal 20110101 |
| Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study. | BMC nephrology 20110101 |
| The hedgehog receptor patched is involved in cholesterol transport. | PloS one 20110101 |
| Neuronal (bi)polarity as a self-organized process enhanced by growing membrane. | PloS one 20110101 |
| Exposure to statins and risk of common cancers: a series of nested case-control studies. | BMC cancer 20110101 |
| Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy. | PloS one 20110101 |
| Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review. | Lipids in health and disease 20110101 |
| Pulsed electromagnetic fields stimulation prevents steroid-induced osteonecrosis in rats. | BMC musculoskeletal disorders 20110101 |
| A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control. | BMC cardiovascular disorders 20110101 |
| Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system. | Journal of pharmacy & bioallied sciences 20110101 |
| The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells. | PloS one 20110101 |
| Intraperitoneal oxygen/ozone treatment decreases the formation of experimental postsurgical peritoneal adhesions and the levels/activity of the local ubiquitin-proteasome system. | Mediators of inflammation 20110101 |
| The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. | PloS one 20110101 |
| Topical treatment of CHILD nevus and Sjögren-Larsson Syndrome with combined lovastatin and cholesterol. | European journal of dermatology : EJD 20110101 |
| Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein. | PloS one 20110101 |
| Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model. | Advances in preventive medicine 20110101 |
| Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | Respiratory research 20110101 |
| Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer. | Journal of thyroid research 20110101 |
| Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids. | Lipids in health and disease 20110101 |
| L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission. | Frontiers in behavioral neuroscience 20110101 |
| Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors. | PloS one 20110101 |
| Optimal production and biochemical properties of a lipase from Candida albicans. | International journal of molecular sciences 20110101 |
| Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | PloS one 20110101 |
| Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis. | PloS one 20110101 |
| Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin. | Lipids in health and disease 20110101 |
| Diffuse Idiopathic Skeletal Hyperostosis (DISH)-A Rare Etiology of Dysphagia. | Clinical medicine insights. Arthritis and musculoskeletal disorders 20110101 |
| Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parameters. | Clinical Medicine Insights. Cardiology 20110101 |
| Use of antimony in the treatment of leishmaniasis: current status and future directions. | Molecular biology international 20110101 |
| Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB. | PloS one 20110101 |
| Adaptation to statins restricts human tumour growth in Nude mice. | BMC cancer 20110101 |
| Regulation of neutrophil survival/apoptosis by Mcl-1. | TheScientificWorldJournal 20110101 |
| Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts. | The Journal of toxicological sciences 20110101 |
| Ras-ERK Signaling in Behavior: Old Questions and New Perspectives. | Frontiers in behavioral neuroscience 20110101 |
| P(5A)-type ATPase Cta4p is essential for Ca2+ transport in the endoplasmic reticulum of Schizosaccharomyces pombe. | PloS one 20110101 |
| Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma. | Sarcoma 20110101 |
| Structural basis and kinetics of force-induced conformational changes of an αA domain-containing integrin. | PloS one 20110101 |
| Interkingdom gene transfer of a hybrid NPS/PKS from bacteria to filamentous Ascomycota. | PloS one 20110101 |
| Decrease in the production of β-amyloid by berberine inhibition of the expression of β-secretase in HEK293 cells. | BMC neuroscience 20110101 |
| Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages. | PloS one 20110101 |
| Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake. | International journal of nanomedicine 20110101 |
| Medical angioplasty - hope and expectations: an optimistic overview. | Journal of family & community medicine 20110101 |
| Assessment of monacolin in the fermented products using Monascus purpureus FTC5391. | Journal of biomedicine & biotechnology 20110101 |
| Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension. | PPAR research 20110101 |
| Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers. | ISRN dentistry 20110101 |
| Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system. | PloS one 20110101 |
| Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. | PloS one 20110101 |
| Preparation and characterization of pioglitazone cyclodextrin inclusion complexes. | Journal of young pharmacists : JYP 20110101 |
| Critical appraisal of ticagrelor in the management of acute coronary syndrome. | Therapeutics and clinical risk management 20110101 |
| Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole. | Clinical pharmacology : advances and applications 20110101 |
| Mthfs is an Essential Gene in Mice and a Component of the Purinosome. | Frontiers in genetics 20110101 |
| Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis. | Scientific reports 20110101 |
| Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. | ISRN pharmaceutics 20110101 |
| No consensus on definition criteria for stroke registry common data elements. | Cerebrovascular diseases extra 20110101 |
| Statin Hepatotoxicity: Is it a Real Concern? | Heart views : the official journal of the Gulf Heart Association 20110101 |
| Statins: past and present. | Heart views : the official journal of the Gulf Heart Association 20110101 |
| Improved bioavailability through floating microspheres of lovastatin. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
| Renoprotective effects of combining ACE inhibitors and statins in experimental diabetic rats. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
| Approach to lipid screening as a risk marker for cardiovascular disease in pediatric patients with diabetes. | Frontiers in endocrinology 20110101 |
| Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter. | Chemistry & biology 20101222 |
| Differential interactions between statins and P-glycoprotein: implications for exploiting statins as anticancer agents. | International journal of cancer 20101215 |
| Membrane raft association of the Vpu protein of human immunodeficiency virus type 1 correlates with enhanced virus release. | Virology 20101205 |
| Effects of Satureja khuzestanica on Serum Glucose, Lipids and Markers of Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Double-Blind Randomized Controlled Trial. | Evidence-based complementary and alternative medicine : eCAM 20101201 |
| Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations. | Investigational new drugs 20101201 |
| Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation. | Annals of the rheumatic diseases 20101201 |
| Lovastatin induces neuronal differentiation and apoptosis of embryonal carcinoma and neuroblastoma cells: enhanced differentiation and apoptosis in combination with dbcAMP. | Molecular and cellular biochemistry 20101201 |
| In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target. | The Journal of clinical endocrinology and metabolism 20101201 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. | Applied microbiology and biotechnology 20101201 |
| IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells. | Cancer research 20101201 |
| Natural variation in Arabidopsis leads to the identification of REME1, a pentatricopeptide repeat-DYW protein controlling the editing of mitochondrial transcripts. | Plant physiology 20101201 |
| Experimental analysis and modelling of in vitro HUVECs proliferation in the presence of various types of drugs. | Cell proliferation 20101201 |
| Response surface methodology for lovastatin production by Aspergillus terreus GD13 strain. | Acta microbiologica et immunologica Hungarica 20101201 |
| d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. | Anticancer research 20101201 |
| Human hydroxymethylglutaryl-coenzyme A reductase (HMGCR) and statin sensitivity. | Indian journal of biochemistry & biophysics 20101201 |
| Tumor specific low pH environments enhance the cytotoxicity of lovastatin and cantharidin. | Cancer letters 20101128 |
| Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. | The Journal of biological chemistry 20101126 |
| Synthesis and antihyperlipidemic activity of novel coumarin bisindole derivatives. | Bioorganic & medicinal chemistry letters 20101115 |
| Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. | Lancet (London, England) 20101113 |
| Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering? | European heart journal 20101101 |
| Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells. | Annals of hematology 20101101 |
| Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany. | Clinical research in cardiology : official journal of the German Cardiac Society 20101101 |
| Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells. | Glia 20101101 |
| Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum. | Biotechnology letters 20101101 |
| Lovastatin raises serum osteoprotegerin level in people with type 2 diabetic nephropathy. | Clinical biochemistry 20101101 |
| Effect of fluvastatin, lovastatin, nifedipine and verapamil on the systemic exposure of nateglinide in rabbits. | Biopharmaceutics & drug disposition 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| The requirement of p53 for maintaining chromosomal stability during tetraploidization. | Oncotarget 20101101 |
| Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! | Archives of internal medicine 20101025 |
| Synthesis and biological evaluation of a series of aromatic bisphosphonates. | Bioorganic & medicinal chemistry 20101015 |
| Accelerated solvent extraction of monacolin K from red yeast rice and purification by high-speed counter-current chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
| Impact of dietary fat type within the context of altered cholesterol homeostasis on cholesterol and lipoprotein metabolism in the F1B hamster. | Metabolism: clinical and experimental 20101001 |
| Cholesterol biosynthesis pathway intermediates and inhibitors regulate glucose-stimulated insulin secretion and secretory granule formation in pancreatic beta-cells. | Endocrinology 20101001 |
| Compromized geranylgeranylation of RhoA and Rac1 in mevalonate kinase deficiency. | Journal of inherited metabolic disease 20101001 |
| Effects of lovastatin on the pharmacokinetics of nicardipine in rats. | Biopharmaceutics & drug disposition 20101001 |
| High Lipoprotein(a) Levels are Associated With Long-Term Adverse Outcomes in Acute Myocardial Infarction Patients in High Killip Classes. | Korean circulation journal 20101001 |
| Are we getting to lipid targets in real life? | Archives of medical science : AMS 20101001 |
| Discovering drug-drug interactions: a text-mining and reasoning approach based on properties of drug metabolism. | Bioinformatics (Oxford, England) 20100915 |
| Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911 |
| Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner. | Neurobiology of aging 20100901 |
| Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats. | Evidence-based complementary and alternative medicine : eCAM 20100901 |
| Do statins beneficially or adversely affect glucose homeostasis? | Current vascular pharmacology 20100901 |
| Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20100901 |
| Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. | Applied microbiology and biotechnology 20100901 |
| Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes. | Biopolymers 20100901 |
| Cholesterol depletion affects infectivity and stability of pseudorabies virus. | Virus research 20100901 |
| Lovastatin inhibits gap junctional communication in cultured aortic smooth muscle cells. | Journal of cardiovascular pharmacology and therapeutics 20100901 |
| Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer. | European urology 20100901 |
| Gluconic acid production by Aspergillus terreus. | Letters in applied microbiology 20100901 |
| Effectiveness, safety and cost of drug substitution in hypertension. | British journal of clinical pharmacology 20100901 |
| Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases. | Expert reviews in molecular medicine 20100901 |
| Conversion investigation for lovastatin and its derivatives by HPLC. | Journal of chromatographic science 20100901 |
| Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study. | PLoS medicine 20100901 |
| Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use. | The western journal of emergency medicine 20100901 |
| Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins. | Oncogene 20100819 |
| [Effects of clinically effective dose of lovastatin on prostate cancer PC3 cells]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20100818 |
| Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex. | Lung cancer (Amsterdam, Netherlands) 20100801 |
| Ichthyosis in Sjögren-Larsson syndrome reflects defective barrier function due to abnormal lamellar body structure and secretion. | Archives of dermatological research 20100801 |
| Inhibitory effects of norcantharidin against human lung cancer cell growth and migration. | Cytotechnology 20100801 |
| Scavenger receptor-B1 and luteal function in mice. | Journal of lipid research 20100801 |
| Colorimetric determination of simvastatin and lovastatin in pure form and in pharmaceutical formulations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100801 |
| Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin. | Reproductive toxicology (Elmsford, N.Y.) 20100801 |
| Immunomodulatory effects of IFN-beta and lovastatin on immunophenotype of monocyte-derived dendritic cells in multiple sclerosis. | Archivum immunologiae et therapiae experimentalis 20100801 |
| Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78. | Translational research : the journal of laboratory and clinical medicine 20100801 |
| Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells. | Anti-cancer drugs 20100801 |
| Acute activation of eNOS by statins involves scavenger receptor-B1, G protein subunit Gi, phospholipase C and calcium influx. | British journal of pharmacology 20100801 |
| Lipid rafts are essential for peroxisome biogenesis in HepG2 cells. | Hepatology (Baltimore, Md.) 20100801 |
| [Effect of lovastatin and rosiglitazone on cholesterol reverse transportation in foam cell]. | Zhonghua nei ke za zhi 20100801 |
| The role of soy in vegetarian diets. | Nutrients 20100801 |
| Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors. | Biochemistry 20100706 |
| Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100701 |
| A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration. | Tissue engineering. Part A 20100701 |
| Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. | Diabetologia 20100701 |
| Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR. | American journal of physiology. Cell physiology 20100701 |
| Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. | Plant physiology 20100701 |
| The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407. | Yonsei medical journal 20100701 |
| Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophy. | Brain pathology (Zurich, Switzerland) 20100701 |
| Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells. | Nutrition research (New York, N.Y.) 20100701 |
| Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease. | Chinese medical journal 20100701 |
| A novel statin-mediated 'prenylation block-and-release' assay provides insight into the membrane targeting mechanisms of small GTPases. | Biochemical and biophysical research communications 20100618 |
| Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani. | Chembiochem : a European journal of chemical biology 20100614 |
| Effect of niacin ER/lovastatin on claudication symptoms in patients with peripheral artery disease. | Vascular medicine (London, England) 20100601 |
| Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: role of NADPH oxidase 4. | Diabetes 20100601 |
| Effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits. | International journal of experimental pathology 20100601 |
| Severe hypocholesterolaemia is often neglected in haematological malignancies. | European journal of cancer (Oxford, England : 1990) 20100601 |
| Statin-associated muscle-related adverse effects: a case series of 354 patients. | Pharmacotherapy 20100601 |
| Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth. | Journal of the American College of Nutrition 20100601 |
| The role of functional foods, nutraceuticals, and food supplements in intestinal health. | Nutrients 20100601 |
| Colloid formation by drugs in simulated intestinal fluid. | Journal of medicinal chemistry 20100527 |
| Lovastatin improves neurological outcome after nucleus basalis magnocellularis lesion in rats. | Neuroscience 20100519 |
| A historical perspective on the discovery of statins. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511 |
| Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. | Journal of cellular and molecular medicine 20100501 |
| Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. | Journal of lipid research 20100501 |
| Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4. | Mucosal immunology 20100501 |
| Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia. | Diabetes care 20100501 |
| Unraveling polyketide synthesis in members of the genus Aspergillus. | Applied microbiology and biotechnology 20100501 |
| Soluble epoxide hydrolase in atherosclerosis. | Current atherosclerosis reports 20100501 |
| HMG-CoA reductase inhibitor lovastatin causes reversible cytoskeleton perturbation by RhoA signalling suppression in peritoneal cell line Met5A. | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20100501 |
| [Mevastatin inhibits the differentiation of thyroid-associated ophthalmopathy derived orbital preadipocytes]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100501 |
| Lipid metabolism and HCV infection. | Viruses 20100501 |
| Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistry. | Chembiochem : a European journal of chemical biology 20100412 |
| Modulation of human T cells signaling transduction by lovastatin. | International journal of cardiology 20100401 |
| Enhancement of lovastatin production by supplementing polyketide antibiotics to the submerged culture of Aspergillus terreus. | Applied biochemistry and biotechnology 20100401 |
| Hormone and pharmaceutical regulation of ASP production in 3T3-L1 adipocytes. | Journal of cellular biochemistry 20100401 |
| Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. | Diabetes 20100401 |
| A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells. | The Journal of pharmacology and experimental therapeutics 20100401 |
| Effects of mevastatin on grafted bone in MRL/MpJ mice. | Connective tissue research 20100401 |
| Radioprotectors and mitigators of radiation-induced normal tissue injury. | The oncologist 20100401 |
| PLoS Computational Biology conference postcards from PSB 2010. | PLoS computational biology 20100401 |
| A systematic review and meta-analysis on the therapeutic equivalence of statins. | Journal of clinical pharmacy and therapeutics 20100401 |
| Effects of grape pomace on the antioxidant defense system in diet-induced hypercholesterolemic rabbits. | Nutrition research and practice 20100401 |
| Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. | Anticancer research 20100401 |
| Ochratoxin a: general overview and actual molecular status. | Toxins 20100401 |
| Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin. | European journal of clinical pharmacology 20100301 |
| Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults. | The Journal of pharmacology and experimental therapeutics 20100301 |
| BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1. | Arteriosclerosis, thrombosis, and vascular biology 20100301 |
| Effect of statins on the viability of macrophages and smooth muscle cells. | Journal of cardiovascular pharmacology 20100301 |
| Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100301 |
| Drug interactions with HMG-CoA reductase inhibitors (statins): the importance of CYP enzymes, transporters and pharmacogenetics. | Current opinion in investigational drugs (London, England : 2000) 20100301 |
| Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome. | Current atherosclerosis reports 20100301 |
| [Establishment of a model for evaluating hypolipidemic effect in HepG2 cells]. | Wei sheng yan jiu = Journal of hygiene research 20100301 |
| Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized rats. | Journal of medicinal chemistry 20100225 |
| Red mold rice promotes neuroprotective sAPPalpha secretion instead of Alzheimer's risk factors and amyloid beta expression in hyperlipidemic Abeta40-infused rats. | Journal of agricultural and food chemistry 20100224 |
| Cholesterol reduction impairs exocytosis of synaptic vesicles. | Journal of cell science 20100215 |
| Improvement of trochanteric bone quality in an osteoporosis model after short-term treatment with parathyroid hormone: a new mechanical test for trochanteric region of rat femur. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20100201 |
| Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro. | Cancer letters 20100201 |
| The isoprenoid pathway and transcriptional response to its inhibitors in the yeast Saccharomyces cerevisiae. | FEMS yeast research 20100201 |
| In vitro interactions between primycin and different statins in their effects against some clinically important fungi. | Journal of medical microbiology 20100201 |
| Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial. | Diabetes care 20100201 |
| The PPR protein encoded by the LOVASTATIN INSENSITIVE 1 gene is involved in RNA editing at three sites in mitochondria of Arabidopsis thaliana. | The Plant journal : for cell and molecular biology 20100201 |
| The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| Lovastatin-induced cholesterol depletion affects both apical sorting and endocytosis of aquaporin-2 in renal cells. | American journal of physiology. Renal physiology 20100201 |
| The mitochondrial PPR protein LOVASTATIN INSENSITIVE 1 plays regulatory roles in cytosolic and plastidial isoprenoid biosynthesis through RNA editing. | The Plant journal : for cell and molecular biology 20100201 |
| Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. | Experimental neurology 20100201 |
| Prediction of cardiovascular event risk reduction from lipid changes associated with high potency dyslipidemia therapy. | Current medical research and opinion 20100201 |
| Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance. | Combinatorial chemistry & high throughput screening 20100201 |
| Measuring hsCRP--an important part of a comprehensive risk profile or a clinically redundant practice? | PLoS medicine 20100201 |
| Lovastatin inhibits the thrombin-induced loss of barrier integrity in bovine corneal endothelium. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20100201 |
| Effect of preoperative statin therapy on myocardial protection and morbidity endpoints following off-pump coronary bypass surgery in patients with elevated C-reactive protein level. | Korean journal of anesthesiology 20100201 |
| Lovastatin in X-linked adrenoleukodystrophy. | The New England journal of medicine 20100121 |
| A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion. | British journal of cancer 20100119 |
| In vivo evidence of duality effects for lovastatin in a nude mouse cancer model. | International journal of cancer 20100115 |
| Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. | The Journal of biological chemistry 20100115 |
| Identification of the mokH gene encoding transcription factor for the upregulation of monacolin K biosynthesis in Monascus pilosus. | Journal of agricultural and food chemistry 20100113 |
| Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+. | The Journal of biological chemistry 20100108 |
| Lovastatin inhibits oxidized L-A-phosphatidylcholine B-arachidonoyl-gamma-palmitoyl (ox-PAPC)-stimulated interleukin-8 mRNA and protein synthesis in human aortic endothelial cells by depleting stores of geranylgeranyl pyrophosphate. | Atherosclerosis 20100101 |
| Development and characterization of a lovastatin-loaded self-microemulsifying drug delivery system. | Pharmaceutical development and technology 20100101 |
| Biotechnological production and applications of statins. | Applied microbiology and biotechnology 20100101 |
| A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction. | Neuroscience letters 20100101 |
| Drug resistance in visceral leishmaniasis. | Journal of biomedicine & biotechnology 20100101 |
| Effect of lovastatin on primary prevention of cardiovascular events in mild CKD and kidney function loss: a post hoc analysis of the Air Force/Texas Coronary Atherosclerosis Prevention Study. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20100101 |
| Targeting viral infection by microRNA inhibition. | Genome biology 20100101 |
| Effects of lovastatin on breast cancer cells: a proteo-metabonomic study. | Breast cancer research : BCR 20100101 |
| An alternative treatment of hyperlipidemia with red yeast rice: a case report. | Journal of medical case reports 20100101 |
| Evaluation of a pig femoral head osteonecrosis model. | Journal of orthopaedic surgery and research 20100101 |
| Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy. | Vascular health and risk management 20100101 |
| Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance. | BMC cancer 20100101 |
| HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival. | BMC nephrology 20100101 |
| Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer. | BMC cancer 20100101 |
| Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells. | Pharmacological reports : PR 20100101 |
| Upregulation of geranylgeranyltransferase I in bronchial smooth muscle of mouse experimental asthma: its inhibition by lovastatin. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101 |
| Simvastatin protects bladder and renal functions following spinal cord injury in rats. | Journal of inflammation (London, England) 20100101 |
| Statins and cognitive functioning in the elderly: a population-based study. | Journal of Alzheimer's disease : JAD 20100101 |
| Statins and the squalene synthase inhibitor zaragozic acid stimulate the non-amyloidogenic pathway of amyloid-beta protein precursor processing by suppression of cholesterol synthesis. | Journal of Alzheimer's disease : JAD 20100101 |
| Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology. | Journal of biomedicine & biotechnology 20100101 |
| High-content, image-based screening for drug targets in yeast. | PloS one 20100101 |
| Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia. | Therapeutics and clinical risk management 20100101 |
| Phenotypic connections in surprising places. | Genome biology 20100101 |
| Cardiovascular dementia - a different perspective. | The open biochemistry journal 20100101 |
| Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins. | Nutricion hospitalaria 20100101 |
| Toxicology and drug delivery by cucurbit[n]uril type molecular containers. | PloS one 20100101 |
| Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis. | Arthritis research & therapy 20100101 |
| A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. | Cellular immunology 20100101 |
| Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. | BMJ (Clinical research ed.) 20100101 |
| Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum. | Malaria journal 20100101 |
| Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis. | PloS one 20100101 |
| Optimization of the fermentation process of actinomycete strain hhs.015. | Journal of biomedicine & biotechnology 20100101 |
| New and extended-action treatments in the management of ADHD: a critical appraisal of lisdexamfetamine in adults and children. | Neuropsychiatric disease and treatment 20100101 |
| The risk for significant creatine kinase elevation with statins. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101 |
| Statins in candidemia: clinical outcomes from a matched cohort study. | BMC infectious diseases 20100101 |
| Dynamics of lamin-A processing following precursor accumulation. | PloS one 20100101 |
| Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication. | Molecular systems biology 20100101 |
| Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia. | Vascular health and risk management 20100101 |
| Lovastatin protects against experimental plague in mice. | PloS one 20100101 |
| Paraoxonase: Its antiatherogenic role in chronic renal failure. | Indian journal of nephrology 20100101 |
| Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. | PloS one 20100101 |
| Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study. | Lipids in health and disease 20100101 |
| Exenatide: a new promising antidiabetic agent. | Indian journal of pharmaceutical sciences 20100101 |
| [With red rice against cholesterol?]. | Duodecim; laaketieteellinen aikakauskirja 20100101 |
| Characterization of the apoptotic response of human leukemia cells to organosulfur compounds. | BMC cancer 20100101 |
| Exobiopolymer production of Ophiocordyceps dipterigena BCC 2073: optimization, production in bioreactor and characterization. | BMC biotechnology 20100101 |
| Osteogenic activity of locally applied small molecule drugs in a rat femur defect model. | Journal of biomedicine & biotechnology 20100101 |
| Effect of apoA-I on cholesterol release and apoE secretion in human mature adipocytes. | Lipids in health and disease 20100101 |
| Differences in efficacy and safety of pharmaceutical treatments between men and women: an umbrella review. | PloS one 20100101 |
| Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations. | Breast cancer research : BCR 20100101 |
| Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism. | BMC biochemistry 20100101 |
| Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination. | Cancer cell international 20100101 |
| Lovastatin inhibits VEGFR and AKT activation: synergistic cytotoxicity in combination with VEGFR inhibitors. | PloS one 20100101 |
| Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study. | Proteome science 20100101 |
| Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway. | Journal of experimental & clinical cancer research : CR 20100101 |
| Analysis of a vascular screening program in a rural community. | Journal of cardiovascular disease research 20100101 |
| Plant sterols, marine-derived omega-3 fatty acids and other functional ingredients: a new frontier for treating hyperlipidemia. | Nutrition & metabolism 20100101 |
| Statins and clinical outcome of acute ischemic stroke: a systematic review. | International archives of medicine 20100101 |
| FasL and FADD delivery by a glioma-specific and cell cycle-dependent HSV-1 amplicon virus enhanced apoptosis in primary human brain tumors. | Molecular cancer 20100101 |
| Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20100101 |
| Benefits of statin therapy and compliance in high risk cardiovascular patients. | Vascular health and risk management 20100101 |
| The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males. | Journal of the International Society of Sports Nutrition 20100101 |
| Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease. | Molecular neurodegeneration 20100101 |
| Drug interaction and pharmacist. | Journal of young pharmacists : JYP 20100101 |
| A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism. | PloS one 20100101 |
| A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.). | BMC plant biology 20100101 |
| Niacin or ezetimibe for patients with, or at risk of coronary heart disease. | Clinical Medicine Insights. Cardiology 20100101 |
| The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101 |
| Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. | BMC molecular biology 20100101 |
| Clinical evaluation of Dyslipidemia among type II diabetic patients at Public hospital Penang, Malaysia. | International archives of medicine 20100101 |
| [Effect of polymorphisms of cytochrome P450 and apolipoprotein E genes on therapeutic efficacy of statins]. | Kardiologiia 20100101 |
| [Effect of lovastatin on adhesive and aggregation function of platelets in patients with arterial hypertension and dislipidemia]. | Klinicheskaia meditsina 20100101 |
| Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells. | Lipids in health and disease 20100101 |
| Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia. | Vascular health and risk management 20100101 |
| Low high-density lipoprotein cholesterol: current status and future strategies for management. | Vascular health and risk management 20100101 |
| Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia. | Vascular health and risk management 20100101 |
| Use of hamster as a model to study diet-induced atherosclerosis. | Nutrition & metabolism 20100101 |
| A novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI. | PloS one 20100101 |
| Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. | PloS one 20100101 |
| Simvastatin impairs murine melanoma growth. | Lipids in health and disease 20100101 |
| Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice. | Lipids in health and disease 20100101 |
| Use of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospital. | International journal of general medicine 20100101 |
| Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy. | Vascular health and risk management 20100101 |
| Optimal management of familial hypercholesterolemia: treatment and management strategies. | Vascular health and risk management 20100101 |
| Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa. | Journal of pain research 20100101 |
| Statins STAT for (over)ventilated patients? | Critical care (London, England) 20100101 |
| Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | Drug design, development and therapy 20100101 |
| Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. | The open cardiovascular medicine journal 20100101 |
| Role of bone marrow-derived monocytes/macrophages in the repair of mucosal damage caused by irradiation and/or anticancer drugs in colitis model. | Mediators of inflammation 20100101 |
| Controversial data on simvastatin in asthma: What about the rat model? | Journal of asthma and allergy 20100101 |
| Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report. | Case reports in medicine 20100101 |
| Pitavastatin: evidence for its place in treatment of hypercholesterolemia. | Core evidence 20100101 |
| Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems. | Cholesterol 20100101 |
| Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease. | Cholesterol 20100101 |
| [Evidence-based grounds of the efficacy of simvastatin (zocor): 15 years later]. | Terapevticheskii arkhiv 20100101 |
| Rosuvastatin counteracts vessel arterialisation and sinusoid capillarisation, reduces tumour growth, and prolongs survival in murine hepatocellular carcinoma. | Gastroenterology research and practice 20100101 |
| Functional toxicogenomics: mechanism-centered toxicology. | International journal of molecular sciences 20100101 |
| Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia. | Drug, healthcare and patient safety 20100101 |
| Screening of nutrient parameters for mevastatin production by Penicillium citrinum MTCC 1256 under submerged fermentation using the Plackett-Burman design. | Journal of pharmacy & bioallied sciences 20100101 |
| Traditional used Plants against Cognitive Decline and Alzheimer Disease. | Frontiers in pharmacology 20100101 |
| Policies to enhance prescribing efficiency in europe: findings and future implications. | Frontiers in pharmacology 20100101 |
| Cytotoxic evaluation of doxorubicin in combination with simvastatin against human cancer cells. | Research in pharmaceutical sciences 20100101 |
| Long-term treatment of patients with HIV-1: the role of atazanavir. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| Individualized initiation of statin therapy determined by baseline LDL-C: Are you more likely to achieve goal LDL-C? | Risk management and healthcare policy 20100101 |
| Comparing the effects of lovastatin and cornus MAS fruit on fibrinogen level in hypercholesterolemic rabbits. | ARYA atherosclerosis 20100101 |
| Iatrogenic Femoral Artery Pseudoaneurysm (REVIEW OF TREATMENT OPTIONS). | ARYA atherosclerosis 20100101 |
| Pharmacological management of metabolic syndrome and its lipid complications. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
| Operons. | Cellular and molecular life sciences : CMLS 20091201 |
| Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201 |
| Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus. | Biotechnology letters 20091201 |
| The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. | Bone 20091201 |
| HTS and hit finding in academia--from chemical genomics to drug discovery. | Drug discovery today 20091201 |
| Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis. | British journal of pharmacology 20091201 |
| Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20091201 |
| Statins: in the beginning. | The journal of the Royal College of Physicians of Edinburgh 20091201 |
| Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids. | Journal of the American Chemical Society 20091125 |
| Simvastatin as a potential therapeutic for acute respiratory distress syndrome. | American journal of respiratory and critical care medicine 20091115 |
| Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism. | Virology 20091110 |
| Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions. | Applied biochemistry and biotechnology 20091101 |
| Aberrant expression of synaptic plasticity-related genes in the NF1+/- mouse hippocampus. | Journal of neuroscience research 20091101 |
| Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin. | Experimental cell research 20091101 |
| Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae. | Analytical biochemistry 20091101 |
| LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20. | Antimicrobial agents and chemotherapy 20091101 |
| 7-Difluoromethyl-5,4'-dimethoxygenistein, a novel genistein derivative, has therapeutic effects on atherosclerosis in a rabbit model. | Journal of cardiovascular pharmacology 20091101 |
| Impact of fixed-dose and multi-pill combination dyslipidemia therapies on medication adherence and the economic burden of sub-optimal adherence. | Current medical research and opinion 20091101 |
| Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins. | International journal of molecular medicine 20091101 |
| Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention. | International journal of oncology 20091101 |
| Quantitative determination of geranyl diphosphate levels in cultured human cells. | Lipids 20091101 |
| A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton. | PLoS computational biology 20091101 |
| Coronary pressure measurement based decision making for percutaneous coronary intervention. | Current cardiology reviews 20091101 |
| Complete reconstitution of a highly reducing iterative polyketide synthase. | Science (New York, N.Y.) 20091023 |
| Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. | The Journal of biological chemistry 20091016 |
| Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells. | Biochemical pharmacology 20091015 |
| Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. | Lipids 20091001 |
| Statin therapy and risk of developing type 2 diabetes: a meta-analysis. | Diabetes care 20091001 |
| Effects of lovastatin on the pharmacokinetics of verapamil and its active metabolite, norverapamil in rats: possible role of P-glycoprotein inhibition by lovastatin. | Archives of pharmacal research 20091001 |
| Preventing and managing cardiometabolic risk: the logic for intervention. | International journal of environmental research and public health 20091001 |
| Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet. | Journal of agricultural and food chemistry 20090923 |
| The Monascus metabolite monacolin K reduces tumor progression and metastasis of Lewis lung carcinoma cells. | Journal of agricultural and food chemistry 20090923 |
| [18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation. | American journal of respiratory and critical care medicine 20090915 |
| Effects of increasing high-density lipoprotein cholesterol and decreasing low-density lipoprotein cholesterol on the incidence of first acute coronary events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study). | The American journal of cardiology 20090915 |
| Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909 |
| Survivin plays as a resistant factor against tamoxifen-induced apoptosis in human breast cancer cells. | Breast cancer research and treatment 20090901 |
| Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901 |
| The use of simvastatin in bone regeneration. | Medicina oral, patologia oral y cirugia bucal 20090901 |
| Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901 |
| Ultrasound assisted ionic liquid dispersive liquid phase extraction of lovastatin and simvastatin: a new pretreatment procedure. | Journal of separation science 20090901 |
| Inhibition of platelet-rich arterial thrombus in vivo: acute antithrombotic effect of intravenous HMG-CoA reductase therapy. | Arteriosclerosis, thrombosis, and vascular biology 20090901 |
| Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). | Journal of cardiovascular translational research 20090901 |
| Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin. | Acta pharmacologica Sinica 20090901 |
| A simple and sensitive HPLC-UV method for quantitation of lovastatin in human plasma: application to a bioequivalence study. | Biological & pharmaceutical bulletin 20090901 |
| REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. | PLoS biology 20090901 |
| Short term treatment with clarithromycin resulting in colchicine-induced rhabdomyolysis. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090901 |
| Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction. | British journal of clinical pharmacology 20090901 |
| Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth. | Journal of cellular and molecular medicine 20090901 |
| Cloning and bioinformatic analysis of lovastatin biosynthesis regulatory gene lovE. | Chinese medical journal 20090805 |
| Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma. | Cancer chemotherapy and pharmacology 20090801 |
| Red yeast rice fermentation by selected Monascus sp. with deep-red color, lovastatin production but no citrinin, and effect of temperature-shift cultivation on lovastatin production. | Applied biochemistry and biotechnology 20090801 |
| Different differentiation of stroma cells from patients with osteonecrosis: a pilot study. | Clinical orthopaedics and related research 20090801 |
| 3-hydroxy 3-methylglutaryl coenzyme A reductase increase is essential for rat muscle differentiation. | Journal of cellular physiology 20090801 |
| Safety evaluation of Monascus purpureus red mould rice in albino rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801 |
| Myelin proteomics: molecular anatomy of an insulating sheath. | Molecular neurobiology 20090801 |
| Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors. | Bioorganic & medicinal chemistry letters 20090801 |
| Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor. | Bioorganic & medicinal chemistry letters 20090801 |
| OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. | Journal of molecular medicine (Berlin, Germany) 20090801 |
| Autocrine amplification loop in statin-induced apoptosis of human melanoma cells. | British journal of pharmacology 20090801 |
| High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART). | Cerebrovascular diseases (Basel, Switzerland) 20090801 |
| High lovastatin production by Aspergillus terreus in solid-state fermentation on polyurethane foam: an artificial inert support. | Journal of bioscience and bioengineering 20090801 |
| No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin. | British journal of clinical pharmacology 20090801 |
| A comparison of pectin, polyphenols, and phytosterols, alone or in combination, to lovastatin for reduction of serum lipids in familial hypercholesterolemic swine. | Journal of medicinal food 20090801 |
| Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target. | Life sciences 20090731 |
| Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR. | Journal of neuroscience research 20090701 |
| Lovastatin inhibits antigen-induced airway eosinophilia without affecting the production of inflammatory mediators in mice. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090701 |
| Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development. | Hepatology (Baltimore, Md.) 20090701 |
| Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells. | British journal of pharmacology 20090701 |
| Comparison of common carotid artery intima-media thickness between Brazilian Euro-descendants and Afro-descendants with atherosclerosis risk factors. | Clinics (Sao Paulo, Brazil) 20090701 |
| Serum levels of lipoprotein(a) and homocysteine in patients on hemodialysis who take hydroxymethylglutaryl-CoA reductase inhibitors, vitamin B6, and folic acid. | Iranian journal of kidney diseases 20090701 |
| Effect of precultural and nutritional parameters on compactin production by solid-state fermentation. | Journal of microbiology and biotechnology 20090701 |
| [Determination of lovastatin and its active metabolites in human plasma with high performance liquid chromatography-tandem mass spectrometry]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090701 |
| Effect of folate supplementation on serum homocysteine and plasma total antioxidant capacity in hypercholesterolemic adults under lovastatin treatment: a double-blind randomized controlled clinical trial. | Archives of medical research 20090701 |
| Acyltransferase mediated polyketide release from a fungal megasynthase. | Journal of the American Chemical Society 20090624 |
| Cholesterol biosynthesis modulation regulates dengue viral replication. | Virology 20090620 |
| Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetes. | Experimental eye research 20090615 |
| Elevated creatine phosphokinase levels associated with linezolid therapy. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090615 |
| Variability in responsiveness to lovastatin of the primitive CD34+ AML subfraction compared to normal CD34+ cells. | Annals of hematology 20090601 |
| High-dose lovastatin decreased basal prostacyclin production in cultured endothelial cells. | Prostaglandins & other lipid mediators 20090601 |
| Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin. | Investigative ophthalmology & visual science 20090601 |
| MlcR, a zinc cluster activator protein, is able to bind to a single (A/T)CGG site of cognate asymmetric motifs in the ML-236B (compactin) biosynthetic gene cluster. | Molecular genetics and genomics : MGG 20090601 |
| Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum. | Applied microbiology and biotechnology 20090601 |
| Statin-induced liver injury involves cross-talk between cholesterol and selenoprotein biosynthetic pathways. | Molecular pharmacology 20090601 |
| Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1. | Experimental biology and medicine (Maywood, N.J.) 20090601 |
| Acute hepatitis caused by a natural lipid-lowering product: when 'alternative' medicine is no 'alternative' at all. | Journal of hepatology 20090601 |
| [Effect of intensive treatment with atorvastatin versus standard doses of statins on the risk of stroke. A meta-analysis from five randomized trials including 25,709 patients]. | Revista de neurologia 20090601 |
| Impact of apolipoprotein A5 variants on statin treatment efficacy. | Pharmacogenomics 20090601 |
| Efflux in fungi: la pièce de résistance. | PLoS pathogens 20090601 |
| Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia. | P & T : a peer-reviewed journal for formulary management 20090601 |
| Screening and selection of lovastatin hyper-producing mutants of Aspergillus terreus using cyclic mutagenesis. | Acta microbiologica et immunologica Hungarica 20090601 |
| Adult reversal of cognitive phenotypes in neurodevelopmental disorders. | Journal of neurodevelopmental disorders 20090601 |
| Human caspase 7 is positively controlled by SREBP-1 and SREBP-2. | The Biochemical journal 20090527 |
| Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins. | Talanta 20090515 |
| Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line. | The Biochemical journal 20090513 |
| How essential is cholesterol? | The Biochemical journal 20090513 |
| Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512 |
| Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography. | Journal of biomechanics 20090511 |
| Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression. | Cancer chemotherapy and pharmacology 20090501 |
| Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines. | European journal of nuclear medicine and molecular imaging 20090501 |
| Digoxin and ouabain increase the synthesis of cholesterol in human liver cells. | Cellular and molecular life sciences : CMLS 20090501 |
| d-δ-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells. | Pancreas 20090501 |
| Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras. | Oncology reports 20090501 |
| Complete blockage of the mevalonate pathway results in male gametophyte lethality. | Journal of experimental botany 20090501 |
| The YTA7 gene is involved in the regulation of the isoprenoid pathway in the yeast Saccharomyces cerevisiae. | FEMS yeast research 20090501 |
| Lovastatin restores the function of endothelial progenitor cells damaged by oxLDL. | Acta pharmacologica Sinica 20090501 |
| Physiological, morphological and kinetic aspects of lovastatin biosynthesis by Aspergillus terreus. | Biotechnology journal 20090501 |
| Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer. | Current oncology (Toronto, Ont.) 20090501 |
| Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis. | Clinics (Sao Paulo, Brazil) 20090501 |
| Trypanosoma cruzi: participation of cholesterol and placental alkaline phosphatase in the host cell invasion. | Experimental parasitology 20090501 |
| Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem. | Current cardiology reviews 20090501 |
| The ginsenoside-Rb2 lowers cholesterol and triacylglycerol levels in 3T3-L1 adipocytes cultured under high cholesterol or fatty acids conditions. | BMB reports 20090430 |
| Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes. | Bioscience, biotechnology, and biochemistry 20090423 |
| Statins for the prevention of dementia. | The Cochrane database of systematic reviews 20090415 |
| The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels. | Journal of human genetics 20090401 |
| AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease. | Clinical science (London, England : 1979) 20090401 |
| A platform to standardize, store, and visualize proteomics experimental data. | Acta biochimica et biophysica Sinica 20090401 |
| Towards prediction of metabolic products of polyketide synthases: an in silico analysis. | PLoS computational biology 20090401 |
| Modified local straight-line screening to detect synthetic drugs in adulterated herbal medicines. | Applied spectroscopy 20090401 |
| C-reactive protein level following treatment and withdrawal of lovastatin in diabetic nephropathy. | Iranian journal of kidney diseases 20090401 |
| HIV entry in macrophages is dependent on intact lipid rafts. | Virology 20090330 |
| Lovastatin induces the formation of abnormal myelin-like membrane sheets in primary oligodendrocytes. | Glia 20090301 |
| Lovastatin potentiates the antidepressant efficacy of fluoxetine in rats. | Pharmacology, biochemistry, and behavior 20090301 |
| Effect of Curcuma kwangsiensis polysaccharides on blood lipid profiles and oxidative stress in high-fat rats. | International journal of biological macromolecules 20090301 |
| Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA. | American journal of physiology. Cell physiology 20090301 |
| Effects of rutin on lipid profile in hypercholesterolaemic rats. | Basic & clinical pharmacology & toxicology 20090301 |
| Rhabdomyolysis caused by a potential sitagliptin-lovastatin interaction. | Pharmacotherapy 20090301 |
| Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway. | PLoS pathogens 20090301 |
| Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo. | Journal of cell communication and signaling 20090301 |
| The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico. | Marine drugs 20090301 |
| Mevinolin enhances osteogenic genes (ALP, type I collagen and osteocalcin), CD44, CD47 and CD51 expression during osteogenic differentiation. | Life sciences 20090227 |
| Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope. | The Biochemical journal 20090215 |
| [Statin therapy and muscle disorders]. | Orvosi hetilap 20090208 |
| [Comment from the lipidologic viewpoint]. | Praxis 20090204 |
| Enhancement of drug solubility in supramolecular and colloidal systems. | Journal of pharmaceutical sciences 20090201 |
| Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation. | Osteoarthritis and cartilage 20090201 |
| Differential influence of different dietary fatty acids on very low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants. | Metabolism: clinical and experimental 20090201 |
| Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia? | Metabolism: clinical and experimental 20090201 |
| Hematologic parameters, atherosclerotic progression, and prognosis in patients with previous coronary artery bypass grafting (from the Post CABG Trial). | The American journal of cardiology 20090201 |
| Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis. | Cancer prevention research (Philadelphia, Pa.) 20090201 |
| Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy. | British journal of clinical pharmacology 20090201 |
| The relationship between reduction in low-density lipoprotein cholesterol by statins and reduction in risk of cardiovascular outcomes: an updated meta-analysis. | Clinical therapeutics 20090201 |
| [Local straight line screening method for the detection of Chinese proprietary medicines containing undeclared prescription drugs]. | Guang pu xue yu guang pu fen xi = Guang pu 20090201 |
| The effect of dyslipidemic drugs on mortality: A meta-analysis. | Indian journal of pharmacology 20090201 |
| Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis. | Glia 20090115 |
| Cloning of the Rhizomucor miehei 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene and its heterologous expression in Mucor circinelloides. | Antonie van Leeuwenhoek 20090101 |
| Aspergillus westerdijkiae polyketide synthase gene 'aoks1' is involved in the biosynthesis of ochratoxin A. | Fungal genetics and biology : FG & B 20090101 |
| Does nicotinic acid (niacin) lower blood pressure? | International journal of clinical practice 20090101 |
| Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. | Bioorganic & medicinal chemistry 20090101 |
| Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus. | BMC chemical biology 20090101 |
| The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. | PloS one 20090101 |
| Survey of physician knowledge regarding antiretroviral medications in hospitalized HIV-infected patients. | Journal of the International AIDS Society 20090101 |
| Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression. | BMC neuroscience 20090101 |
| Effects of statins on the secretion of human serum albumin in cultured HepG2 cells. | Journal of biomedical science 20090101 |
| Campylobacter jejuni induces transcellular translocation of commensal bacteria via lipid rafts. | Gut pathogens 20090101 |
| Fungal type I polyketide synthases. | Methods in enzymology 20090101 |
| Neuroprotective effects of statins in an in vitro model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
| Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction. | Journal of Alzheimer's disease : JAD 20090101 |
| Chapter 2. From microbial products to novel drugs that target a multitude of disease indications. | Methods in enzymology 20090101 |
| The influence of lovastatin on thrombomodulin gene expression in vascular endothelial cells--in vitro study. | Folia histochemica et cytobiologica 20090101 |
| Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C. | Current gerontology and geriatrics research 20090101 |
| Role of atazanavir in the treatment of HIV infection. | Therapeutics and clinical risk management 20090101 |
| Efficacy and safety of rosuvastatin in the management of dyslipidemia. | Vascular health and risk management 20090101 |
| Prevention of atherosclerosis in patients living with HIV. | Vascular health and risk management 20090101 |
| Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin. | Vascular health and risk management 20090101 |
| Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis. | Cardiovascular diabetology 20090101 |
| Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately? | The open neurology journal 20090101 |
| Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk. | Vascular health and risk management 20090101 |
| Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors. | Vascular health and risk management 20090101 |
| Impact of statins and ACE inhibitors on mortality after COPD exacerbations. | Respiratory research 20090101 |
| SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. | PloS one 20090101 |
| Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA binding. | Drug and chemical toxicology 20090101 |
| The biosynthesis and accumulation of beta-carotene in Dunaliella salina proceed via the glyceraldehyde 3-phosphate/pyruvate pathway. | Natural product research 20090101 |
| Statin use and risk of community acquired pneumonia in older people: population based case-control study. | BMJ (Clinical research ed.) 20090101 |
| Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial. | Trials 20090101 |
| Effect of HMG-CoA reductase inhibitors on activation of human gammadeltaT cells induced by Mycobacterium tuberculosis antigens. | Immunopharmacology and immunotoxicology 20090101 |
| Postulated vasoactive neuropeptide immunopathology affecting the blood-brain/blood-spinal barrier in certain neuropsychiatric fatigue-related conditions: A role for phosphodiesterase inhibitors in treatment? | Neuropsychiatric disease and treatment 20090101 |
| A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation. | PloS one 20090101 |
| The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials. | BMJ (Clinical research ed.) 20090101 |
| Leptin stimulated C-reactive protein production by human coronary artery endothelial cells. | Journal of vascular research 20090101 |
| Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke. | Journal of biomedical science 20090101 |
| Associations between statins and COPD: a systematic review. | BMC pulmonary medicine 20090101 |
| Statin-induced calcification in human mesenchymal stem cells is cell death related. | Journal of cellular and molecular medicine 20090101 |
| Regulation of bile acid and cholesterol metabolism by PPARs. | PPAR research 20090101 |
| New options in the treatment of lipid disorders in HIV-infected patients. | The open AIDS journal 20090101 |
| Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry. | BMC public health 20090101 |
| Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | Interdisciplinary perspectives on infectious diseases 20090101 |
| Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir. | Therapeutics and clinical risk management 20090101 |
| Utilization of genomic signatures to identify phenotype-specific drugs. | PloS one 20090101 |
| Myopathy with concurrent tadalafil and simvastatin. | Case reports in medicine 20090101 |
| Magnetic resonance imaging of the natural history of in situ mammary neoplasia in transgenic mice: a pilot study. | Breast cancer research : BCR 20090101 |
| Management of avascular necrosis of femoral head at pre-collapse stage. | Indian journal of orthopaedics 20090101 |
| Effects of lovastatin and pentoxyphyllin in nonalcoholic steatohepatitis. | Hepato-gastroenterology 20090101 |
| Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment. | Toxicology mechanisms and methods 20090101 |
| Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. | Molecular cancer 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| [Statins in practice of the vascular surgeon and cardiologist]. | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20090101 |
| Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk. | Vascular health and risk management 20090101 |
| Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels. | Molecular vision 20090101 |
| A 60-year-old man with chronic renal failure and a costal mass: a case report and review of the literature. | Journal of medical case reports 20090101 |
| Pleiotropic vasoprotective effects of statins: the chicken or the egg? | Drug design, development and therapy 20090101 |
| Increased frequency and nocturia in a middle aged male may not always be due to Benign Prostatic Hypertrophy (BPH): a case report. | Cases journal 20090101 |
| Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease. | Lipids in health and disease 20090101 |
| Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles. | PloS one 20090101 |
| Influenza morbidity and mortality in elderly patients receiving statins: a cohort study. | PloS one 20090101 |
| Management of dyslipidemia in children. | Diabetology & metabolic syndrome 20090101 |
| [Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study]. | Wiener medizinische Wochenschrift (1946) 20090101 |
| Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report. | Diagnostic pathology 20090101 |
| Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway. | BMC cancer 20090101 |
| Model system for the analysis of cell surface expression of human ABCA1. | BMC cell biology 20090101 |
| SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance. | Orphanet journal of rare diseases 20090101 |
| The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences. | Vascular health and risk management 20090101 |
| Dermatomyositis presenting with rhabdomyolysis and acute renal failure; an uncommon manifestation. | Annals of Indian Academy of Neurology 20090101 |
| Lipid abnormalities in streptozotocin-diabetes: Amelioration by Morus indica L. cv Suguna leaves. | International journal of diabetes in developing countries 20090101 |
| Increased frequency and nocturia in a middle aged male may not always be due to benign prostatic hypertrophy: a case report. | Cases journal 20090101 |
| Lovastatin and fluvastatin reduce viremia and the pro-inflammatory cytokines in the patients with chronic hepatitis C. | Hepato-gastroenterology 20090101 |
| Acute coronary syndrome in pregnancy. | Clinical medicine. Cardiology 20090101 |
| Targeted therapy in the treatment of malignant gliomas. | OncoTargets and therapy 20090101 |
| Epidemiologic characteristics and risk factors for renal cell cancer. | Clinical epidemiology 20090101 |
| Raising HDL cholesterol in women. | International journal of women's health 20090101 |
| Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective. | Diabetes, metabolic syndrome and obesity : targets and therapy 20090101 |
| Enhanced cytostatic activity of statins in mouse mammary carcinoma cells overexpressing β2-chimaerin. | Molecular medicine reports 20090101 |
| Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics. | Drug, healthcare and patient safety 20090101 |
| Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae. | FEBS letters 20081210 |
| Berberine decreases PCSK9 expression in HepG2 cells. | Atherosclerosis 20081201 |
| Statin cost-effectiveness comparisons using real-world effectiveness data: formulary implications. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20081201 |
| Lovastatin inhibits adipogenesis and prevents osteonecrosis in steroid-treated rabbits. | Joint, bone, spine : revue du rhumatisme 20081201 |
| Actin cytoskeleton remodeling governs aquaporin-4 localization in astrocytes. | Glia 20081201 |
| Interaction between statins and clopidogrel: is there anything clinically relevant? | QJM : monthly journal of the Association of Physicians 20081201 |
| Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis. | Experimental neurology 20081201 |
| Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state. | Journal of molecular medicine (Berlin, Germany) 20081201 |
| Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201 |
| Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA. | Molecular genetics and genomics : MGG 20081201 |
| Myotoxicity of lipid-lowering agents in a teenager with MELAS mutation. | Pediatric neurology 20081201 |
| Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer. | Cancer science 20081201 |
| Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression. | Journal of medicinal food 20081201 |
| Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats. | Archives of pharmacal research 20081201 |
| Solubility enhancement of lovastatin by modified locust bean gum using solid dispersion techniques. | AAPS PharmSciTech 20081201 |
| Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin. | Comparative medicine 20081201 |
| Fifth International Workshop on the CCN Family of Genes: Abstracts and Posters October 18-22, 2008. | Journal of cell communication and signaling 20081201 |
| Report on the fifth international workshop on the CCN family of genes. | Journal of cell communication and signaling 20081201 |
| Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients. | Clinical therapeutics 20081201 |
| [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201 |
| Systems biology: a therapeutic target for tumor therapy. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
| An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS). | Neuropsychiatric disease and treatment 20081201 |
| Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy. | Vascular health and risk management 20081201 |
| Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma. | Biologics : targets & therapy 20081201 |
| Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases. | Journal of clinical lipidology 20081201 |
| Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients. | Journal of the American College of Cardiology 20081125 |
| The influence of statin medications on prostate-specific antigen levels. | Journal of the National Cancer Institute 20081105 |
| SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. | The Journal of clinical investigation 20081103 |
| Transdermal lovastatin enhances fracture repair in rats. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20081101 |
| Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081101 |
| Impact of adherence to statins on chronic heart failure in primary prevention. | British journal of clinical pharmacology 20081101 |
| Spatial and temporal analysis of pharmaceutical concentrations in the upper Tennessee River basin. | Chemosphere 20081101 |
| Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet. | International journal of obesity (2005) 20081101 |
| An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system. | Pharmacoepidemiology and drug safety 20081101 |
| Pleiotropic effect of lovastatin, with and without cholestyramine, in the post coronary artery bypass graft (Post CABG) trial. | The American journal of cardiology 20081015 |
| Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status. | Journal of neuro-oncology 20081001 |
| Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii. | The Journal of antimicrobial chemotherapy 20081001 |
| Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins. | Diabetes 20081001 |
| AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells. | Arteriosclerosis, thrombosis, and vascular biology 20081001 |
| Statins limit Rickettsia conorii infection in cells. | International journal of antimicrobial agents 20081001 |
| A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model. | Innate immunity 20081001 |
| A gift from nature: the birth of the statins. | Nature medicine 20081001 |
| Grapefruit juice-drug interaction studies as a method to assess the extent of intestinal availability: utility and limitations. | Current drug metabolism 20081001 |
| Renal failure and rhabdomyolysis associated with sitagliptin and simvastatin use. | Diabetic medicine : a journal of the British Diabetic Association 20081001 |
| Excess coronary artery disease risk in South Asian immigrants: can dysfunctional high-density lipoprotein explain increased risk? | Vascular health and risk management 20081001 |
| The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction. | Vascular health and risk management 20081001 |
| Frequency of secondary dyslipidemia in obese children. | Vascular health and risk management 20081001 |
| Miscellaneous. | Indian journal of pharmacology 20081001 |
| Autonomic nervous system and cardiovascular system. | Indian journal of pharmacology 20081001 |
| Lovastatin inhibits TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts. | Investigative ophthalmology & visual science 20080901 |
| Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. | International journal of cancer 20080901 |
| Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds. | Drug metabolism and disposition: the biological fate of chemicals 20080901 |
| Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins. | Arteriosclerosis, thrombosis, and vascular biology 20080901 |
| Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36. | Diabetes 20080901 |
| Identification of the specific sequence recognized by Penicillium citrinum MlcR, a GAL4-type transcriptional activator of ML-236B (compactin) biosynthetic genes. | Fungal genetics and biology : FG & B 20080901 |
| BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model. | International journal of oncology 20080901 |
| Statins induce regulatory T cell recruitment via a CCL1 dependent pathway. | Journal of immunology (Baltimore, Md. : 1950) 20080901 |
| Therapy of X-linked adrenoleukodystrophy. | Expert review of neurotherapeutics 20080901 |
| Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis. | Journal of clinical biochemistry and nutrition 20080901 |
| HIV infection in the elderly. | Clinical interventions in aging 20080901 |
| Study of the intima-media thickening in carotid arteries of healthy elderly with high blood pressure and elderly with high blood pressure and dyslipidemia. | Clinical interventions in aging 20080901 |
| Can HMG Co-A reductase inhibitors ('statins') slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). | Clinical interventions in aging 20080901 |
| Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy. | International journal of nanomedicine 20080901 |
| The relationship between obesity and atherosclerotic progression and prognosis among patients with coronary artery bypass grafts the effect of aggressive statin therapy. | Journal of the American College of Cardiology 20080819 |
| Mevinolin, citrinin and pigments of adlay angkak fermented by Monascus sp. | International journal of food microbiology 20080815 |
| Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition. | Bioorganic & medicinal chemistry letters 20080815 |
| Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. | Neuroscience letters 20080808 |
| Detection of Lipitor counterfeits: a comparison of NIR and Raman spectroscopy in combination with chemometrics. | Journal of pharmaceutical and biomedical analysis 20080805 |
| Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells. | Pflugers Archiv : European journal of physiology 20080801 |
| Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress. | Neurochemical research 20080801 |
| Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program. | Clinical pharmacology and therapeutics 20080801 |
| Lovastatin effect in rat neuroblasts of the CNS: inhibition of cap-dependent translation. | Journal of neurochemistry 20080801 |
| Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin. | Journal of neurochemistry 20080801 |
| Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit. | Cardiovascular drugs and therapy 20080801 |
| Subclinical atherosclerosis: what it is, what it means and what we can do about it. | International journal of clinical practice 20080801 |
| Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic. | Bioorganic & medicinal chemistry 20080801 |
| Lipophilicity and cardiovascular outcome in patients with CHF. | American heart journal 20080801 |
| Redispersible, dry emulsion of lovastatin protects against intestinal metabolism and improves bioavailability. | Acta pharmacologica Sinica 20080801 |
| Synchronization of the cell cycle using lovastatin. | Cell cycle (Georgetown, Tex.) 20080801 |
| The Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART): an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke. | International journal of stroke : official journal of the International Stroke Society 20080801 |
| A practical protocol to measure common carotid artery intima-media thickness. | Clinics (Sao Paulo, Brazil) 20080801 |
| Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni. | Memorias do Instituto Oswaldo Cruz 20080801 |
| [Lovastatin protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis through activation of PI3K/Akt and ERK1/2 signaling pathways]. | Zhonghua xin xue guan bing za zhi 20080801 |
| Posaconazole in the management of refractory invasive fungal infections. | Therapeutics and clinical risk management 20080801 |
| The Relationship Between HIV Infection and Cardiovascular Disease. | Current cardiology reviews 20080801 |
| Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus. | Journal of agricultural and food chemistry 20080723 |
| Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins. | FEBS letters 20080723 |
| Solubility of lovastatin in a family of six alcohols: Ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, and 1-octanol. | International journal of pharmaceutics 20080709 |
| Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells. | The Journal of nutritional biochemistry 20080701 |
| Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions. | Proteins 20080701 |
| Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia. | European journal of clinical pharmacology 20080701 |
| Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. | The Journal of pharmacology and experimental therapeutics 20080701 |
| Red mold rice extract represses amyloid beta peptide-induced neurotoxicity via potent synergism of anti-inflammatory and antioxidative effect. | Applied microbiology and biotechnology 20080701 |
| Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase. | PLoS biology 20080701 |
| Rhabdomyolysis and pancreatitis associated with coadministration of danazol 600 mg/d and lovastatin 40 mg/d. | Clinical therapeutics 20080701 |
| Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line. | Experimental cell research 20080610 |
| Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. | The Journal of biological chemistry 20080606 |
| Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease. | Journal of neurochemistry 20080601 |
| Atorvastatin and uptake of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) in human monocyte-macrophages: implications for magnetic resonance imaging. | Biomaterials 20080601 |
| Impact of the FcgammaII-receptor on quartz uptake and inflammatory response by alveolar macrophages. | American journal of physiology. Lung cellular and molecular physiology 20080601 |
| The comparative effectiveness of rosuvastatin vs. other statins in patients with an increased risk of failure to reach NCEP ATP III goal. | International journal of clinical practice 20080601 |
| Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study. | Journal of clinical psychopharmacology 20080601 |
| Environmental induction of white-opaque switching in Candida albicans. | PLoS pathogens 20080601 |
| Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20080601 |
| Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical. | The AAPS journal 20080601 |
| Atorvastatin and cardiovascular risk in the elderly--patient considerations. | Clinical interventions in aging 20080601 |
| [Pleiotropic effects of statins]. | Revista medica de Chile 20080601 |
| [Advance in the study of compounds inducing the expression of heme oxygenase-1]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080601 |
| The use of fondaparinux for the treatment of venous thromboembolism in a patient with heparin-induced thombocytopenia and thrombosis caused by heparin flushes. | Therapeutics and clinical risk management 20080601 |
| Relative safety profiles of high dose statin regimens. | Vascular health and risk management 20080601 |
| Can consumers self-select for appropriate use of an over-the-counter statin? The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment Study. | The American journal of cardiology 20080515 |
| Zooplankton chitobiase activity as an endpoint of pharmaceutical effect. | Archives of environmental contamination and toxicology 20080501 |
| Determination of lovastatin in human plasma by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry. | Biomedical chromatography : BMC 20080501 |
| Histone modifications and chromatin dynamics: a focus on filamentous fungi. | FEMS microbiology reviews 20080501 |
| Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. | Molecular pharmacology 20080501 |
| Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts. | Journal of neurochemistry 20080501 |
| Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease. | Journal of thrombosis and haemostasis : JTH 20080501 |
| Lovastatin inhibits formation of AA amyloid. | Journal of leukocyte biology 20080501 |
| Therapeutic potential of statins in thyroid proliferative disease. | Nature clinical practice. Endocrinology & metabolism 20080501 |
| Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts. | American journal of physiology. Heart and circulatory physiology 20080501 |
| Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. | Applied microbiology and biotechnology 20080501 |
| Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance. | Eukaryotic cell 20080501 |
| Atorvastatin monotherapy vs. combination therapy in the management of patients with combined hyperlipidemia. | European journal of internal medicine 20080501 |
| Lovastatin biosynthetic genes of Aspergillus terreus are expressed differentially in solid-state and in liquid submerged fermentation. | Applied microbiology and biotechnology 20080501 |
| Lovastatin enhances the antitumoral and apoptotic activity of doxorubicin in murine tumor models. | Oncology reports 20080501 |
| [Determination of simvastatin in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20080501 |
| The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080423 |
| Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN2/CTGF expression. | The Journal of biological chemistry 20080418 |
| The safety of niacin in the US Food and Drug Administration adverse event reporting database. | The American journal of cardiology 20080417 |
| The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. | Atherosclerosis 20080401 |
| Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors. | Journal of cellular physiology 20080401 |
| Regulation of the PTEN promoter by statins and SREBP. | Human molecular genetics 20080401 |
| Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients. | Molecular genetics and metabolism 20080401 |
| Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake. | Molecular pharmacology 20080401 |
| Lovastatin inhibits bronchial hyperresponsiveness by reducing RhoA signaling in rat allergic asthma. | American journal of physiology. Lung cellular and molecular physiology 20080401 |
| Mechanisms of leukocyte migration across the blood-retina barrier. | Seminars in immunopathology 20080401 |
| Differential regulation of neutrophil CD18 integrin function by di- and tri-valent cations: manganese vs. gadolinium. | Annals of biomedical engineering 20080401 |
| Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | Liver international : official journal of the International Association for the Study of the Liver 20080401 |
| Lipid levels and low-density lipoprotein cholesterol goal attainment in diabetic patients: rosuvastatin compared with other statins in usual care. | Expert opinion on pharmacotherapy 20080401 |
| Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | The American journal of gastroenterology 20080401 |
| Statins in esophageal cancer cell lines: promising lead? | The American journal of gastroenterology 20080401 |
| Statins and cancer risk. | The American journal of medicine 20080401 |
| Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo. | Cancer biology & therapy 20080401 |
| Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. | Cancer research 20080401 |
| Biphasic effects of atorvastatin on inflammation. | Pakistan journal of pharmaceutical sciences 20080401 |
| [Use of statins in children]. | Anales de pediatria (Barcelona, Spain : 2003) 20080401 |
| Determination of lovastatin hydroxy acid in female B6C3F1 mouse serum. | Journal of analytical toxicology 20080401 |
| A multipronged approach to prostate cancer. | Cancer biology & therapy 20080401 |
| Pharmacological topics of bone metabolism: antiresorptive microbial compounds that inhibit osteoclast differentiation, function, and survival. | Journal of pharmacological sciences 20080401 |
| [Effect of assorted use of Chinese drugs for detoxifying and activating blood circulation on serum high sensitive C-reactive protein in apolipoprotein E gene knock-out mice]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080401 |
| Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | Vascular health and risk management 20080401 |
| Clinical efficacy and safety of statins in managing cardiovascular risk. | Vascular health and risk management 20080401 |
| Preferred drug lists: potential impact on healthcare economics. | Vascular health and risk management 20080401 |
| Monascus purpureus Went rice in nephrotic hyperlipidemia. | Indian journal of nephrology 20080401 |
| Rapid liquid chromatography-tandem mass spectrometry method for the determination of a broad mixture of pharmaceuticals in surface water. | Journal of chromatography. A 20080328 |
| Differences in antitumor effects of various statins on human pancreatic cancer. | International journal of cancer 20080315 |
| Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease. | World journal of gastroenterology 20080314 |
| An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma. | Journal of pharmaceutical and biomedical analysis 20080313 |
| Determination of lovastatin in human plasma by ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry and its application in a pharmacokinetic study. | Journal of pharmaceutical and biomedical analysis 20080313 |
| Inhibition of ABC transporters abolishes antimony resistance in Leishmania Infection. | Antimicrobial agents and chemotherapy 20080301 |
| Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes. | The Journal of pharmacology and experimental therapeutics 20080301 |
| The Food and Drug Administration and over-the-counter statins: an opportunity lost? | Journal of clinical hypertension (Greenwich, Conn.) 20080301 |
| Flexible initial dosing of atorvastatin based upon initial low-density lipoprotein cholesterol levels in type 2 diabetic patients. | The Korean journal of internal medicine 20080301 |
| Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. | PLoS medicine 20080301 |
| Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways. | Journal of Alzheimer's disease : JAD 20080301 |
| [Prescription patterns for antilipidemic drugs in a group of Colombian patients]. | Revista panamericana de salud publica = Pan American journal of public health 20080301 |
| [Biosynthesis of simvastatin--a mini-review]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301 |
| Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation. | Journal of neuroscience methods 20080215 |
| Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway. | Biochemical pharmacology 20080215 |
| Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis. | Journal of neuro-oncology 20080201 |
| The economic consequences of noncompliance in cardiovascular disease and related conditions: a literature review. | International journal of clinical practice 20080201 |
| Class effects of statins in elderly patients with congestive heart failure: a population-based analysis. | American heart journal 20080201 |
| New developments in medulloblastoma treatment: the potential of a cyclopamine-lovastatin combination. | Expert opinion on investigational drugs 20080201 |
| Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | Leukemia & lymphoma 20080201 |
| Comparative anticancer effects of flavonoids and diazepam in cultured cancer cells. | Biological & pharmaceutical bulletin 20080201 |
| Pharmacokinetics and bioequivalence study of two tablet formulations of lovastatin in healthy volunteers. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20080201 |
| Red yeast rice and omega-3 fatty acids for cholesterol management. | South Dakota medicine : the journal of the South Dakota State Medical Association 20080201 |
| Update on the use of fibrates: focus on bezafibrate. | Vascular health and risk management 20080201 |
| Perioperative use of statins in noncardiac surgery. | Vascular health and risk management 20080201 |
| High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease. | Vascular health and risk management 20080201 |
| The real code of leonardo da vinci. | Current cardiology reviews 20080201 |
| Comparing pharmacokinetic and pharmacodynamic profiles in female rats orally exposed to lovastatin by gavage versus diet. | Chemico-biological interactions 20080130 |
| The association between statins and cancer incidence in a veterans population. | Journal of the National Cancer Institute 20080116 |
| Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors. | Biochemical pharmacology 20080115 |
| FDA advisers again reject nonprescription lovastatin. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080115 |
| Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. | Biochemical and biophysical research communications 20080111 |
| Lovastatin protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt and ERK1/2. | Journal of cellular biochemistry 20080101 |
| Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080101 |
| Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101 |
| Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. | Planta 20080101 |
| Screening statins for possible carcinogenic risk: up to 9 years of follow-up of 361,859 recipients. | Pharmacoepidemiology and drug safety 20080101 |
| Pancreatic stellate cells: new target in the treatment of chronic pancreatitis. | Journal of gastroenterology and hepatology 20080101 |
| Statin use and risk of breast cancer. | Cancer 20080101 |
| In vitro mechanisms of lovastatin on lung cancer cell lines as a potential chemopreventive agent. | Lung 20080101 |
| Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming growth factor-beta1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells. | Translational research : the journal of laboratory and clinical medicine 20080101 |
| Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet. | Metabolism: clinical and experimental 20080101 |
| Ciglitazone, an agonist of peroxisome proliferator-activated receptor gamma, exerts potentiated cytostatic/cytotoxic effects against tumor cells when combined with lovastatin. | International journal of oncology 20080101 |
| Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20080101 |
| The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | BMC cancer 20080101 |
| Statin induces apoptosis and cell growth arrest in prostate cancer cells. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101 |
| Incidence of adverse events with HMG-CoA reductase inhibitors in liver transplant patients. | Clinical transplantation 20080101 |
| Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi. | Genome biology 20080101 |
| Cell cycle and cell death are not necessary for appressorium formation and plant infection in the fungal plant pathogen Colletotrichum gloeosporioides. | BMC biology 20080101 |
| Peroxisome proliferator activated receptors and lipoprotein metabolism. | PPAR research 20080101 |
| Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor. | BMC evolutionary biology 20080101 |
| Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study. | Drug safety 20080101 |
| Does productivity influence priority setting? A case study from the field of CVD prevention. | Cost effectiveness and resource allocation : C/E 20080101 |
| [New approaches to the drug prophylaxis of mammary tumor: evaluation of the prophylactic effect of lovastatin and captopril in rats with experimental mammary gland tumors]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
| Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort study. | Drug safety 20080101 |
| The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease. | BMC nephrology 20080101 |
| Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT. | AIDS research and therapy 20080101 |
| Chinese red yeast rice (Monascus purpureus-fermented rice) promotes bone formation. | Chinese medicine 20080101 |
| Analysis of Aspergillus nidulans metabolism at the genome-scale. | BMC genomics 20080101 |
| Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial. | Lipids in health and disease 20080101 |
| Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas. | Molecular cancer 20080101 |
| Interaction of the HMG-CoA reductase inhibitor lovastatin and nitric oxide in cardiomyocyte cell death. | Pharmacology 20080101 |
| A Role for the PPARgamma in Cancer Therapy. | PPAR research 20080101 |
| Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin. | Clinical pharmacokinetics 20080101 |
| Potentiation of nerve growth factor-induced neurite outgrowth by fluvoxamine: role of sigma-1 receptors, IP3 receptors and cellular signaling pathways. | PloS one 20080101 |
| Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key? | PPAR research 20080101 |
| Secondary prevention of coronary heart disease in elderly patients following myocardial infarction: are all HMG-CoA reductase inhibitors alike? | Drugs & aging 20080101 |
| Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin. | BMC medicine 20080101 |
| Statins, bone, and neurofibromatosis type 1. | BMC medicine 20080101 |
| Yeast cell factories for fine chemical and API production. | Microbial cell factories 20080101 |
| 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases. | Journal of inflammation (London, England) 20080101 |
| Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats. | BMC pharmacology 20080101 |
| Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells. | PPAR research 20080101 |
| Use of rosiglitazone before and after vascular injury in hypercholesterolemic rabbits: Assessment of neointimal formation. | Thrombosis journal 20080101 |
| Effects of krill oil on serum lipids of hyperlipidemic rats and human SW480 cells. | Lipids in health and disease 20080101 |
| Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats. | European journal of drug metabolism and pharmacokinetics 20080101 |
| PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents. | PPAR research 20080101 |
| Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. | BMC biology 20080101 |
| Non-healing painful ulcers in a patient with chronic kidney disease and role of sodium thiosulfate: a case report. | Cases journal 20080101 |
| Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models. | Breast cancer research : BCR 20080101 |
| Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20080101 |
| The prince and the pauper. A tale of anticancer targeted agents. | Molecular cancer 20080101 |
| In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites. | BMC bioinformatics 20080101 |
| Net efficacy adjusted for risk (NEAR): a simple procedure for measuring risk:benefit balance. | PloS one 20080101 |
| Implementing shared decision-making in nutrition clinical practice: a theory-based approach and feasibility study. | Implementation science : IS 20080101 |
| The effects of lovastatin on conventional medical treatment of lower urinary tract symptoms with finasteride. | International braz j urol : official journal of the Brazilian Society of Urology 20080101 |
| Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | BMC systems biology 20080101 |
| Defective rotavirus particle assembly in lovastatin-treated MA104 cells. | Archives of virology 20080101 |
| Design of floating bilayer tablets of diltiazem hydrochloride and lovastatin. | PDA journal of pharmaceutical science and technology 20080101 |
| Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors. | PPAR research 20080101 |
| PPARgamma, PTEN, and the Fight against Cancer. | PPAR research 20080101 |
| Clinical Use of PPARgamma Ligands in Cancer. | PPAR research 20080101 |
| Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts. | Developmental neuroscience 20080101 |
| HMG-CoA reductase is regulated by environmental salinity and its activity is essential for halotolerance in halophilic fungi. | Studies in mycology 20080101 |
| Statin treatment, carotid atherosclerotic plaque macrophage infiltration and circulating inflammatory markers. | The open cardiovascular medicine journal 20080101 |
| Sphincter of Oddi and its dysfunction. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20080101 |
| Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | Analytical chemistry insights 20080101 |
| Microbial production and biomedical applications of lovastatin. | Indian journal of pharmaceutical sciences 20080101 |
| Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis. | Open medicine : a peer-reviewed, independent, open-access journal 20080101 |
| A simple and rapid approach for removing citrinin while retaining monacolin K in red mold rice. | Journal of agricultural and food chemistry 20071226 |
| The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. | The Journal of clinical investigation 20071203 |
| Comparison of a dietary portfolio diet of cholesterol-lowering foods and a statin on LDL particle size phenotype in hypercholesterolaemic participants. | The British journal of nutrition 20071201 |
| Simultaneous biosynthesis of (+)-geodin by a lovastatin-producing fungus Aspergillus terreus. | Journal of biotechnology 20071201 |
| Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. | Lipids 20071201 |
| Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. | Plant cell reports 20071201 |
| P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors. | Experimental hematology 20071201 |
| Hypolipidemic and antioxidant effects of ethanolic extract from dried calyx of Hibiscus sabdariffa in alloxan-induced diabetic rats. | Fundamental & clinical pharmacology 20071201 |
| The antitumour activities of statins. | Current oncology (Toronto, Ont.) 20071201 |
| Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma. | Molecular cancer therapeutics 20071201 |
| Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting. | The American journal of managed care 20071201 |
| 3-hydroxy-3-methylglutaryl coenzyme a reductase 1 interacts with NORK and is crucial for nodulation in Medicago truncatula. | The Plant cell 20071201 |
| Aliskiren--an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension. | Vascular health and risk management 20071201 |
| The antioxidant effect of lovastatin on phagocyte-induced DNA damage: implications for cancer prevention. | Journal of experimental & clinical cancer research : CR 20071201 |
| [Protection of vascular endothelial cells from ox-LDL induced injury by protocatechualdehyde]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201 |
| Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. | Current neuropharmacology 20071201 |
| Structural elucidation of an unknown Simvastatin by-product in industrial synthesis starting from Lovastatin. | Journal of pharmaceutical and biomedical analysis 20071130 |
| The impact of generic reference pricing interventions in the statin market. | Health policy (Amsterdam, Netherlands) 20071101 |
| Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid beta-infused rat by repressing amyloid beta accumulation. | Journal of neuroscience research 20071101 |
| Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells. | Endocrinology 20071101 |
| Lovastatin induces the expression of bradykinin type 2 receptors in cultured human coronary artery endothelial cells. | Journal of molecular and cellular cardiology 20071101 |
| Effect of combining viscous fibre with lovastatin on serum lipids in normal human subjects. | International journal of clinical practice 20071101 |
| Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071101 |
| Cholesterol-lowering drugs and prostate cancer risk: a population-based case-control study. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071101 |
| Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro. | Molecular cancer therapeutics 20071101 |
| Comparative evaluation of the effects of statins on human stem and cancer cells in vitro. | Reproductive biomedicine online 20071101 |
| Antifungal activity of statins against Aspergillus species. | Medical mycology 20071101 |
| Titration patterns with rosuvastatin as compared with other statins in clinical practice: a retrospective observational cohort study using an electronic medical record database. | Clinical therapeutics 20071101 |
| Comparison of a statin vs. hypolipemic diet on the oxidant status in hemodialyzed patients with chronic renal failure. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071101 |
| Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis. | Journal of cell science 20071015 |
| Activation of the integrated stress response regulates lovastatin-induced apoptosis. | The Journal of biological chemistry 20071012 |
| Locally delivered lovastatin nanoparticles enhance fracture healing in rats. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20071001 |
| Risk of congenital anomalies in pregnant users of statin drugs. | British journal of clinical pharmacology 20071001 |
| Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. | Cell biology international 20071001 |
| Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy. | Clinical endocrinology 20071001 |
| P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
| ICAM-1 peptide inhibitors of T-cell adhesion bind to the allosteric site of LFA-1. An NMR characterization. | Chemical biology & drug design 20071001 |
| Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data. | International journal of clinical practice 20071001 |
| The road to LOAD: late-onset Alzheimer's disease and a possible way to block it. | Expert opinion on therapeutic targets 20071001 |
| The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway. | Gastroenterology 20071001 |
| Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon. | Journal of pharmacological sciences 20071001 |
| A meta-analysis to evaluate the efficacy of statins in children with familial hypercholesterolemia. | International journal of clinical pharmacology and therapeutics 20071001 |
| Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. | Journal of cardiovascular pharmacology 20071001 |
| The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation. | Vascular health and risk management 20071001 |
| Cholesterol lowering for secondary prevention: what statin dose should we use? | Vascular health and risk management 20071001 |
| Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors. | Vascular health and risk management 20071001 |
| Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration. | Toxicology and applied pharmacology 20070915 |
| Statins reduce amyloid-beta production through inhibition of protein isoprenylation. | The Journal of biological chemistry 20070914 |
| Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells. | European journal of pharmacology 20070910 |
| Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901 |
| A phase I study to assess the safety and activity of topical lovastatin (FP252S) for the prevention of chemotherapy-induced alopecia. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070901 |
| Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons. | American journal of physiology. Heart and circulatory physiology 20070901 |
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | Biopharmaceutics & drug disposition 20070901 |
| Effect of statin and angiotensin-converting enzyme inhibition on structural and hemodynamic alterations in autosomal dominant polycystic kidney disease model. | American journal of physiology. Renal physiology 20070901 |
| Effectiveness of rosuvastatin in low-density lipoprotein cholesterol lowering and National Cholesterol Education Program Adult Treatment Panel guideline III LDL-C goal attainment compared to other statins among diabetes mellitus patients: a retrospective study using an electronic medical records dataset in the United States. | Current medical research and opinion 20070901 |
| Lovastatin enhances phenylbutyrate-induced MR-visible glycerophosphocholine but not apoptosis in DU145 prostate cells. | Biochimica et biophysica acta 20070901 |
| A new perspective on nonprescription statins: an opportunity for patient education and involvement. | The American journal of cardiology 20070901 |
| Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology. | Journal of medicinal food 20070901 |
| Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice. | The American journal of geriatric pharmacotherapy 20070901 |
| Ask the doctor. I saw a newspaper column that said red yeast rice is a safer, more effective way to treat high cholesterol than statin drugs. Is that true? | Harvard heart letter : from Harvard Medical School 20070901 |
| The molecular genetics of breast cancer and targeted therapy. | Biologics : targets & therapy 20070901 |
| Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation. | Veterinary microbiology 20070831 |
| Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease. | Neurology 20070828 |
| Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters. | Journal of agricultural and food chemistry 20070822 |
| Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation. | Biochemical pharmacology 20070815 |
| Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition. | Journal of agricultural and food chemistry 20070808 |
| Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity. | Cancer immunology, immunotherapy : CII 20070801 |
| Statins in elderly patients with acute coronary syndrome: an analysis of dose and class effects in typical practice. | Heart (British Cardiac Society) 20070801 |
| Effect of reduced levels of the LDL receptor of Ehrlich ascites tumor cells on cholesterol uptake and cell proliferation: a coculture study with baby hamster kidney cells. | Cell biology international 20070801 |
| Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid. | Drug metabolism and disposition: the biological fate of chemicals 20070801 |
| Simvastatin inhibits IFN-gamma-induced CD40 gene expression by suppressing STAT-1alpha. | Journal of leukocyte biology 20070801 |
| Establishing the benefit of statins in low-to-moderate--risk primary prevention: the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). | Atherosclerosis. Supplements 20070801 |
| On the factors modulating the effect of statins on malignant cell proliferation. | Cancer investigation 20070801 |
| Impact of statin dosing intensity on transaminase and creatine kinase. | The American journal of medicine 20070801 |
| Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. | PLoS pathogens 20070801 |
| Prolonged-release nicotinic acid for the management of dyslipidemia: an update including results from the NAUTILUS study. | Vascular health and risk management 20070801 |
| Review of tipranavir in the treatment of drug-resistant HIV. | Therapeutics and clinical risk management 20070801 |
| Evaluation of patient care interventions and recommendations by a transitional care pharmacist. | Therapeutics and clinical risk management 20070801 |
| Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. | Journal of the American College of Cardiology 20070731 |
| Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial. | Journal of the American College of Cardiology 20070724 |
| A macrokinetic modelling of the biosynthesis of lovastatin by Aspergillus terreus. | Journal of biotechnology 20070715 |
| Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors. | Journal of medicinal chemistry 20070712 |
| Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer. | The Journal of biological chemistry 20070706 |
| Lovastatin improves histological and functional outcomes and reduces inflammation after experimental traumatic brain injury. | Life sciences 20070704 |
| Esterase inhibition attribute of grapefruit juice leading to a new drug interaction. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | The Journal of pharmacology and experimental therapeutics 20070701 |
| Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma. | Journal of lipid research 20070701 |
| Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus. | FEMS microbiology letters 20070701 |
| Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells. | European journal of cell biology 20070701 |
| Improving simvastatin bioconversion in Escherichia coli by deletion of bioH. | Metabolic engineering 20070701 |
| Effects of lactose and glucose on production of itaconic acid and lovastatin by Aspergillus terreus ATCC 20542. | Journal of bioscience and bioengineering 20070701 |
| What do medical records tell us about potentially harmful co-prescribing? | Joint Commission journal on quality and patient safety 20070701 |
| Chromatography-mass spectrometry methods for the quantitation of statins in biological samples. | Journal of pharmaceutical and biomedical analysis 20070628 |
| Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy. | Investigational new drugs 20070601 |
| Modulation of COX-2 expression by statins in human monocytic cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070601 |
| Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. | American journal of respiratory cell and molecular biology 20070601 |
| Effects of statins on bone mineral density: a meta-analysis of clinical studies. | Bone 20070601 |
| Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB. | The FEBS journal 20070601 |
| Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo. | International journal of oncology 20070601 |
| German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version). | Archives of dermatological research 20070601 |
| Lovastatin effects on bone mineral density in postmenopausal women with type 2 diabetes mellitus. | Acta diabetologica 20070601 |
| Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma. | Molecular cancer therapeutics 20070601 |
| Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans. | PLoS pathogens 20070601 |
| [Experimental study of anti-atherosclerosis potency by lycium seed oil and its possible mechanism]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601 |
| Studies on free radicals, antioxidants, and co-factors. | Clinical interventions in aging 20070601 |
| Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation. | Blood 20070515 |
| Interactions between statins and Penicillium chrysogenum antifungal protein (PAF) to inhibit the germination of sporangiospores of different sensitive Zygomycetes. | FEMS microbiology letters 20070501 |
| Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells. | Neurochemistry international 20070501 |
| Lovastatin specifically prevents focal ischemic ventricular tachycardia due to triggered activity. | Heart rhythm 20070501 |
| Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line. | Journal of cardiovascular pharmacology 20070501 |
| In vitro study of lovastatin interactions with amiodarone and with carbon tetrachloride in isolated rat hepatocytes. | World journal of gastroenterology 20070421 |
| Beneficial effect of statins in multiple sclerosis: is it dose-dependent? | Atherosclerosis 20070401 |
| Partial silencing of a hydroxy-methylglutaryl-CoA reductase-encoding gene in Trichoderma harzianum CECT 2413 results in a lower level of resistance to lovastatin and lower antifungal activity. | Fungal genetics and biology : FG & B 20070401 |
| Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors. | Bioorganic & medicinal chemistry letters 20070401 |
| Stacking and quantitative analysis of lovastatin in urine samples by the transient moving chemical reaction boundary method in capillary electrophoresis. | Analytical and bioanalytical chemistry 20070401 |
| The effect of aggressive versus conventional lipid-lowering therapy on markers of inflammatory and oxidative stress. | Cardiovascular drugs and therapy 20070401 |
| Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. | Nature chemical biology 20070401 |
| Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo. | Experimental biology and medicine (Maywood, N.J.) 20070401 |
| [Lovastatin induction of the redundant gene: implications for therapy of X-linked adrenoleukodystrophy]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20070401 |
| The potential antioxidant capacity and angiotensin I-converting enzyme inhibitory activity of Monascus-fermented soybean extracts: evaluation of Monascus-fermented soybean extracts as multifunctional food additives. | Journal of food science 20070401 |
| Effect of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors and antioxidant vitamins on free radical lipid oxidation in rat liver. | Bulletin of experimental biology and medicine 20070401 |
| Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine. | Veterinary microbiology 20070310 |
| [The neurobiology of learning difficulties: neurofibromatosis type 1 as a model for researching and treating learning disorders]. | Revista de neurologia 20070302 |
| Role of microglia in the pathogenesis of osmotic-induced demyelination. | Experimental neurology 20070301 |
| Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling. | The Journal of physiology 20070301 |
| Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
| Treatment of experimental autoimmune uveoretinitis with atorvastatin and lovastatin. | Experimental eye research 20070301 |
| Predicting the oxidative metabolism of statins: an application of the MetaSite algorithm. | Pharmaceutical research 20070301 |
| High-dose methylprednisolone influences the physiology and virulence of Candida albicans ambiguously and enhances the candidacidal activity of the polyene antibiotic amphotericin B and the superoxide-generating agent menadione. | FEMS yeast research 20070301 |
| Lovastatin attenuates nerve injury in an animal model of Guillain-Barré syndrome. | Journal of neurochemistry 20070301 |
| Functional analysis of the hepatic HMG-CoA reductase promoter by in vivo electroporation. | Experimental biology and medicine (Maywood, N.J.) 20070301 |
| Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles. | AAPS PharmSciTech 20070301 |
| Neuropsychiatric consequences of cardiovascular medications. | Dialogues in clinical neuroscience 20070301 |
| C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line. | Life sciences 20070227 |
| Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin. | The Journal of biological chemistry 20070223 |
| Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase. | Biochemical and biophysical research communications 20070223 |
| Statin-induced Ras activation integrates the phosphatidylinositol 3-kinase signal to Akt and MAPK for bone morphogenetic protein-2 expression in osteoblast differentiation. | The Journal of biological chemistry 20070216 |
| Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck. | British journal of cancer 20070212 |
| Effects of statin treatment and withdrawal on angiotensin II-induced phosphorylation of p38 MAPK and ERK1/2 in cultured vascular smooth muscle cells. | Biochemical and biophysical research communications 20070202 |
| Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling. | Neuroscience letters 20070202 |
| Haplotypes in the lipoprotein lipase gene influence high-density lipoprotein cholesterol response to statin therapy and progression of atherosclerosis in coronary artery bypass grafts. | The pharmacogenomics journal 20070201 |
| Effect of a statin on an in vitro model of endometriosis. | Fertility and sterility 20070201 |
| Decrease of cholesterol in mouse melanoma causes secretion of lysosomal enzymes. | Journal of biochemistry 20070201 |
| Lovastatin insensitive 1, a Novel pentatricopeptide repeat protein, is a potential regulatory factor of isoprenoid biosynthesis in Arabidopsis. | Plant & cell physiology 20070201 |
| Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity. | Annals of surgery 20070201 |
| The use of statins in postoperative adhesion prevention. | Annals of surgery 20070201 |
| c-Jun N-terminal protein kinase signalling pathway mediates lovastatin-induced rat brain neuroblast apoptosis. | Biochimica et biophysica acta 20070201 |
| Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system). | The American journal of cardiology 20070201 |
| Exenatide effects on statin pharmacokinetics and lipid response. | International journal of clinical pharmacology and therapeutics 20070201 |
| Estimating the impact of adding C-reactive protein as a criterion for lipid lowering treatment in the United States. | Journal of general internal medicine 20070201 |
| Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy. | Clinical therapeutics 20070201 |
| Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. | Vascular health and risk management 20070201 |
| Lovastatin and cyclopamine combination in medulloblastoma. | Cancer biology & therapy 20070201 |
| Production of dihydroisocoumarins in Fusarium verticillioides by swapping ketosynthase domain of the fungal iterative polyketide synthase Fum1p with that of lovastatin diketide synthase. | Journal of the American Chemical Society 20070110 |
| Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes. | Circulation research 20070105 |
| Quantitative analysis of lovastatin in capsule of Chinese medicine monascus by capillary zone electrophoresis with UV-vis detector. | Journal of pharmaceutical and biomedical analysis 20070104 |
| Syntheses of conjugated pyrones for the enzymatic assay of lovastatin nonaketide synthase, an iterative polyketide synthase. | Organic letters 20070104 |
| Herpes zoster-associated acute urinary retention: a case report. | International urogynecology journal and pelvic floor dysfunction 20070101 |
| Supplementation of the cultivation media with B-group vitamins enhances lovastatin biosynthesis by Aspergillus terreus. | Journal of biotechnology 20070101 |
| Phenantroline, lovastatin, and mebendazole do not inhibit oviposition in the murine experimental infection with Angiostrongylus costaricensis. | Parasitology research 20070101 |
| Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts. | The Biochemical journal 20070101 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Optimization of nutrient parameters for lovastatin production by Monascus purpureus MTCC 369 under submerged fermentation using response surface methodology. | Applied microbiology and biotechnology 20070101 |
| Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment. | Molecular pharmacology 20070101 |
| Influences of lovastatin on membrane ion flow and intracellular signaling in breast cancer cells. | Cellular & molecular biology letters 20070101 |
| Therapeutic approach to FSGS in children. | Pediatric nephrology (Berlin, Germany) 20070101 |
| Apolipoprotein E genotype affects the response to lipid-lowering therapy in Chinese patients with type 2 diabetes mellitus. | Diabetes, obesity & metabolism 20070101 |
| Hedgehog signaling promotes medulloblastoma survival via Bc/II. | The American journal of pathology 20070101 |
| Optimal low-density lipoprotein cholesterol lowering--morning versus evening statin administration. | The Annals of pharmacotherapy 20070101 |
| Probable statin-induced testicular pain. | The Annals of pharmacotherapy 20070101 |
| [Regulatory effect of Chinese herbal compound for detoxifying and activating blood circulation on expression of NF-kappaB and MMP-9 in aorta of apolipoprotein E gene knocked-out mice]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070101 |
| Cost-effectiveness of medical interventions to prevent cardiovascular disease in a sub-Saharan African country--the case of Tanzania. | Cost effectiveness and resource allocation : C/E 20070101 |
| Chemical combination effects predict connectivity in biological systems. | Molecular systems biology 20070101 |
| The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | Immunity & ageing : I & A 20070101 |
| How equitable are GP practice prescribing rates for statins?: an ecological study in four primary care trusts in North West England. | International journal for equity in health 20070101 |
| The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. | Molecular cancer 20070101 |
| The lipid lowering effect of plant sterol ester capsules in hypercholesterolemic subjects. | Lipids in health and disease 20070101 |
| Risk and predictability of drug interactions in the elderly. | International review of neurobiology 20070101 |
| Physicochemical characterization and dissolution study of solid dispersions of Lovastatin with polyethylene glycol 4000 and polyvinylpyrrolidone K30. | Pharmaceutical development and technology 20070101 |
| Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1. | PloS one 20070101 |
| Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir. | Journal of the American Board of Family Medicine : JABFM 20070101 |
| Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. | BMC medicine 20070101 |
| Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells. | Clinical hemorheology and microcirculation 20070101 |
| Reduction of protein synthesis and statin-induced cardiomyocyte cell death. | Cardiovascular toxicology 20070101 |
| General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs. | Clinical pharmacokinetics 20070101 |
| HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells. | Journal of vascular research 20070101 |
| Should we encourage over-the-counter statins? A population perspective for coronary heart disease prevention. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101 |
| Regression or reduction in progression of atherosclerosis, and avoidance of coronary events, with lovastatin in patients with or at high risk of cardiovascular disease: a review. | Clinical drug investigation 20070101 |
| An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data. | BMC pharmacology 20070101 |
| The Role of PPARs in Lung Fibrosis. | PPAR research 20070101 |
| Determination of pitavastatin in human plasma via HPLC-ESI-MS/MS and subsequent application to a clinical study in healthy Chinese volunteers. | Clinica chimica acta; international journal of clinical chemistry 20070101 |
| The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data. | Genome biology 20070101 |
| Locally applied Simvastatin improves fracture healing in mice. | BMC musculoskeletal disorders 20070101 |
| Monascus rice products. | Advances in food and nutrition research 20070101 |
| Dissecting complex transcriptional responses using pathway-level scores based on prior information. | BMC bioinformatics 20070101 |
| Increased expression of CD14 in macrophages after inhibition of the cholesterol biosynthetic pathway by lovastatin. | Molecular medicine (Cambridge, Mass.) 20070101 |
| Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. | Lipids in health and disease 20070101 |
| Medicinal importance of grapefruit juice and its interaction with various drugs. | Nutrition journal 20070101 |
| Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line. | BMC cancer 20070101 |
| Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors. | Methods in molecular biology (Clifton, N.J.) 20070101 |
| The Ontario printed educational message (OPEM) trial to narrow the evidence-practice gap with respect to prescribing practices of general and family physicians: a cluster randomized controlled trial, targeting the care of individuals with diabetes and hypertension in Ontario, Canada. | Implementation science : IS 20070101 |
| Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report. | Lipids in health and disease 20070101 |
| A critical gap between recommended and achieved LDL-cholesterol levels. Results of statin therapy in Slovakia. | Bratislavske lekarske listy 20070101 |
| Peroxisome proliferator-activated receptors in lung cancer. | PPAR research 20070101 |
| Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats. | Nutrition research and practice 20070101 |
| Elevated K-ras activity with cholestyramine and lovastatin, but not konjac mannan or niacin in lung--importance of mouse strain. | Biochemical pharmacology 20061215 |
| Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. | European journal of pharmacology 20061215 |
| Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21. | British journal of cancer 20061204 |
| Osteogenic gene expression decreases in stromal cells of patients with osteonecrosis. | Clinical orthopaedics and related research 20061201 |
| Colchicine and HMG Co-A reductase inhibitors induced myopathy-a case report. | Neurotoxicology 20061201 |
| Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide. | British journal of pharmacology 20061201 |
| Berberine, a natural cholesterol reducing product, exerts antitumor cytostatic/cytotoxic effects independently from the mevalonate pathway. | Oncology reports 20061201 |
| Lovastatin possesses a fungistatic effect against Candida albicans, but does not trigger apoptosis in this opportunistic human pathogen. | FEMS yeast research 20061201 |
| Chemopreventive agents alters global gene expression pattern: predicting their mode of action and targets. | Current cancer drug targets 20061201 |
| Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. | Clinical pharmacology and therapeutics 20061201 |
| Regulation of hepatic cholesterol metabolism in CETP/LDLr mice by cholesterol feeding and by drugs (cholestyramine and lovastatin) that lower plasma cholesterol. | Clinical and experimental pharmacology & physiology 20061201 |
| Molecular diagnosis of a BRAF papillary thyroid carcinoma with multiple chromosome abnormalities and rare adrenal and hypothalamic metastases. | Thyroid : official journal of the American Thyroid Association 20061201 |
| Lipid lowering inefficacy of high-dose statin therapy due to concurrent use of phenytoin. | Southern medical journal 20061201 |
| Who should receive a statin drug to lower cardiovascular risk? Does the drug and the dose of the drug matter? | Vascular health and risk management 20061201 |
| Phenotypic conversion leads to structural and functional changes of smooth muscle sarcolemma. | Experimental cell research 20061101 |
| HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway. | Journal of molecular medicine (Berlin, Germany) 20061101 |
| Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. | The Journal of clinical endocrinology and metabolism 20061101 |
| Plasma cholesterol is hyperresponsive to statin in ABCG5/ABCG8 transgenic mice. | Hepatology (Baltimore, Md.) 20061101 |
| Role of P-glycoprotein in statin drug interactions. | Pharmacotherapy 20061101 |
| Statins, fibrates, and melanoma risk: a systematic review and meta-analysis. | Journal of the National Cancer Institute 20061101 |
| Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. | Chemistry & biology 20061101 |
| Distribution of lovastatin to bone and its effect on bone turnover in rats. | The Journal of pharmacy and pharmacology 20061101 |
| Statins inhibit the dimerization of beta-secretase via both isoprenoid- and cholesterol-mediated mechanisms. | The Biochemical journal 20061015 |
| Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent--monacolin K and antiinflammation agent--monascin. | Applied microbiology and biotechnology 20061001 |
| Influence of cholesterol and lovastatin on alpha-form of secreted amyloid precursor protein and expression of alpha7 nicotinic receptor on astrocytes. | Neurochemistry international 20061001 |
| Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. | Pharmacology & therapeutics 20061001 |
| Neopterin induces pro-atherothrombotic phenotype in human coronary endothelial cells. | Journal of thrombosis and haemostasis : JTH 20061001 |
| Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | Molecular reproduction and development 20061001 |
| The role of geranylgeranylated proteins in human mesangial cell proliferation. | Kidney international 20061001 |
| Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway. | Fertility and sterility 20061001 |
| Cost efficiency and formulary considerations for statin therapy. | The American journal of managed care 20061001 |
| Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia. | Neuropeptides 20061001 |
| MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation. | The Journal of biological chemistry 20060915 |
| An automated blood sampling system to measure lovastatin level in plasma and faeces. | Biomedical chromatography : BMC 20060901 |
| The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901 |
| Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. | The American journal of pathology 20060901 |
| Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin. | The Journal of clinical investigation 20060901 |
| Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells. | Molecular cancer therapeutics 20060901 |
| Stimulation of an alpha1-adrenergic receptor downregulates ecto-5' nucleotidase activity on the apical membrane of RPE cells. | Purinergic signalling 20060901 |
| Proteomic analysis of Caco-2 cells treated with monacolin K. | Journal of agricultural and food chemistry 20060823 |
| Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation. | Human molecular genetics 20060815 |
| Herbicidal effects of statin pharmaceuticals in Lemna gibba. | Environmental science & technology 20060815 |
| Roles of endogenously synthesized sterols in the endocytic pathway. | The Journal of biological chemistry 20060811 |
| Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes. | Brain research 20060809 |
| Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin. | Current microbiology 20060801 |
| Clinical inquiries. Which medications can be split without compromising efficacy and safety? | The Journal of family practice 20060801 |
| Effect of red mold rice supplements on serum and meat cholesterol levels of broilers chicken. | Applied microbiology and biotechnology 20060801 |
| Statins in the treatment of chronic heart failure: a systematic review. | PLoS medicine 20060801 |
| Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancer. | Urologic nursing 20060801 |
| [Protective effect of effective parts of Zingiber Offecinal on vascular endothelium of the experimental hyperlipidemic rats]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060801 |
| Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060715 |
| Alzheimer-like plaque formation by human macrophages is reduced by fibrillation inhibitors and lovastatin. | Journal of molecular biology 20060707 |
| Inhibitory effects of statins on human monocarboxylate transporter 4. | International journal of pharmaceutics 20060706 |
| Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma. | International journal of cancer 20060701 |
| A comparative study on the antimutagenicity of atorvastatin and lovastatin against directly acting mutagens. | Cell biology and toxicology 20060701 |
| Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis. | Annals of neurology 20060701 |
| Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis. | Biochimica et biophysica acta 20060701 |
| Lovastatin-induced apoptosis in macrophages through the Rac1/Cdc42/JNK pathway. | Journal of immunology (Baltimore, Md. : 1950) 20060701 |
| Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol. | Traffic (Copenhagen, Denmark) 20060701 |
| Different anti-HCV profiles of statins and their potential for combination therapy with interferon. | Hepatology (Baltimore, Md.) 20060701 |
| Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec data. | American heart journal 20060701 |
| Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury. | Journal of neuropathology and experimental neurology 20060701 |
| Study on the conversion of three natural statins from lactone forms to their corresponding hydroxy acid forms and their determination in Pu-Erh tea. | Journal of chromatography. A 20060630 |
| Peroxisomal cholesterol biosynthesis and Smith-Lemli-Opitz syndrome. | Biochemical and biophysical research communications 20060623 |
| Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. | Journal of immunology (Baltimore, Md. : 1950) 20060615 |
| Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells. | Cancer letters 20060608 |
| Effects of the sporulation conditions on the lovastatin production by Aspergillus terreus. | Bioprocess and biosystems engineering 20060601 |
| Polyamine depletion and cell cycle manipulation in combination with HSV thymidine kinase/ganciclovir cancer gene therapy. | International journal of oncology 20060601 |
| Randomized comparative study of the effects of treatment with once-daily, niacin extended-release/lovastatin and with simvastatin on lipid profile and fibrinolytic parameters in Taiwan. | The Kaohsiung journal of medical sciences 20060601 |
| Repression of secondary metabolite production by exogenous cAMP in Monascus. | Bioscience, biotechnology, and biochemistry 20060601 |
| Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies. | Clinical therapeutics 20060601 |
| Lipoprotein-associated phospholipase A2, vascular inflammation and cardiovascular risk prediction. | Vascular health and risk management 20060601 |
| Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence. | Vascular health and risk management 20060601 |
| Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review. | International journal of nanomedicine 20060601 |
| Statin use and breast cancer: prospective results from the Women's Health Initiative. | Journal of the National Cancer Institute 20060517 |
| Increased PTEN expression due to transcriptional activation of PPARgamma by Lovastatin and Rosiglitazone. | International journal of cancer 20060515 |
| Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo. | Biochemical and biophysical research communications 20060512 |
| Statins and stroke: current clinical practice. | Stroke 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study). | The American journal of cardiology 20060501 |
| Moderate alcohol consumption and safety of lovastatin and warfarin among men: the post-coronary artery bypass graft trial. | The American journal of medicine 20060501 |
| The quantification of monacolin K in some red yeast rice from Fujian province and the comparison of the other product. | Chemical & pharmaceutical bulletin 20060501 |
| Effects of the principal nutrients on lovastatin production by Monascus pilosus. | Bioscience, biotechnology, and biochemistry 20060501 |
| Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints. | Reviews on recent clinical trials 20060501 |
| Statin safety and drug interactions: clinical implications. | The American journal of cardiology 20060417 |
| Statin safety: a systematic review. | The American journal of cardiology 20060417 |
| Proapoptotic and antitumor activities of the HMG-CoA reductase inhibitor, lovastatin, against Dalton's lymphoma ascites tumor in mice. | Clinica chimica acta; international journal of clinical chemistry 20060401 |
| Lovastatin and thalidomide have a combined effect on the rate of multiple myeloma cell apoptosis in short term cell cultures. | European journal of clinical pharmacology 20060401 |
| The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose. | European journal of clinical pharmacology 20060401 |
| Effect of rosuvastatin compared with other statins on lipid levels and National Cholesterol Education Program goal attainment for low-density lipoprotein cholesterol in a usual care setting. | Pharmacotherapy 20060401 |
| Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid-lowering therapy. | Journal of internal medicine 20060401 |
| Retrospective review of sex differences in the management of dyslipidemia in coronary heart disease: an analysis of patient data from a Maryland-based health maintenance organization. | Clinical therapeutics 20060401 |
| The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats. | European journal of pharmacology 20060327 |
| Potential impact on cardiovascular public health of over-the-counter statin availability. | The American journal of cardiology 20060315 |
| Analysis of five HMG-CoA reductase inhibitors-- atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies. | Biomedical chromatography : BMC 20060301 |
| Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport. | Pharmaceutical research 20060301 |
| HMG-CoA reductase inhibitors induce apoptosis in pericytes. | Microvascular research 20060301 |
| Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells. | Allergy 20060301 |
| Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism. | Cellular microbiology 20060301 |
| Evidence-based prescribing of statins: a developing world perspective. | PLoS medicine 20060301 |
| Exenatide. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060301 |
| Low high-density lipoprotein cholesterol and cardiovascular disease: risk reduction with statin therapy. | American heart journal 20060301 |
| N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
| Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction. | Journal of the American Geriatrics Society 20060301 |
| Inhibitory effect of Magnolia officinalis and lovastatin on aortic oxidative stress and apoptosis in hyperlipidemic rabbits. | Journal of cardiovascular pharmacology 20060301 |
| Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer's disease. | Cardiovascular & hematological disorders drug targets 20060301 |
| [Lowering plasma homocysteine with vitamins B6, B12, and folic acid. Effect on lipids concentration in patients with secondary hyperlipoproteinemia type IV, with and without Lovastatina treatment]. | Archivos latinoamericanos de nutricion 20060301 |
| Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination. | Vascular health and risk management 20060301 |
| Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study. | Vascular health and risk management 20060301 |
| Dietary approaches that delay age-related diseases. | Clinical interventions in aging 20060301 |
| Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia. | Therapeutics and clinical risk management 20060301 |
| Formal enantioselective synthesis of (+)-compactin. | Organic letters 20060216 |
| Statins induce calcium-dependent mitochondrial permeability transition. | Toxicology 20060215 |
| Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone. | International journal of cancer 20060201 |
| The prion protein requires cholesterol for cell surface localization. | Molecular and cellular neurosciences 20060201 |
| Rho/ROCK pathway as a target of tumor therapy. | Journal of neuroscience research 20060201 |
| Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells. | Immunology and cell biology 20060201 |
| Alcohol consumption, atherosclerotic progression, and prognosis among patients with coronary artery bypass grafts. | American heart journal 20060201 |
| The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201 |
| Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
| Lovastatin reduces apoptosis and downregulates the CD40 expression induced by TNF-alpha in cerebral vascular endothelial cells. | Current neurovascular research 20060201 |
| Kinetics and mechanisms of cholesterol esterase inhibition by cardiovascular drugs in vitro. | Indian journal of biochemistry & biophysics 20060201 |
| Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells. | Biochemical and biophysical research communications 20060120 |
| Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. | Blood 20060115 |
| Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome. | Cancer research 20060115 |
| Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies. | Cancer chemotherapy and pharmacology 20060101 |
| Erythropoietin receptor signal transduction requires protein geranylgeranylation. | The Journal of pharmacology and experimental therapeutics 20060101 |
| HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways. | Cellular signalling 20060101 |
| Cleavage of focal adhesion proteins and PKCdelta during lovastatin-induced apoptosis in spontaneously immortalized rat brain neuroblasts. | The FEBS journal 20060101 |
| Statins and osteoporosis: new role for old drugs. | The Journal of pharmacy and pharmacology 20060101 |
| Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol. | Phytotherapy research : PTR 20060101 |
| Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro. | Pharmacology 20060101 |
| Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line. | BMC cancer 20060101 |
| Statin wars following coronary revascularization--evidence-based clinical practice? | The Canadian journal of cardiology 20060101 |
| New treatment strategies for multiple myeloma by targeting BCL-2 and the mevalonate pathway. | Current pharmaceutical design 20060101 |
| Statin-related adverse events: a meta-analysis. | Clinical therapeutics 20060101 |
| Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. | Molecular cancer 20060101 |
| Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo. | BMC biochemistry 20060101 |
| [Correction of thrombocyte-vascular hemostasis in metabolic syndrome]. | Klinicheskaia meditsina 20060101 |
| Fluvastatin does not elevate periosteal osteogenesis induce by Moloney sarcoma virus (MSV) in mice. | Pharmacological reports : PR 20060101 |
| Guinea pigs: a suitable animal model to study lipoprotein metabolism, atherosclerosis and inflammation. | Nutrition & metabolism 20060101 |
| Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines. | Cancer cell international 20060101 |
| Lovastatin production by Pleurotus ostreatus: effects of the C:N ratio. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101 |
| Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia. | Journal of neuroinflammation 20060101 |
| Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome. | Orphanet journal of rare diseases 20060101 |
| A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240]. | Implementation science : IS 20060101 |
| Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20060101 |
| Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts. | Arthritis research & therapy 20060101 |
| Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice. | Neuromolecular medicine 20060101 |
| Cost-effectiveness analysis of cholesterol-lowering therapies in Spain. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101 |
| Synchronous analysis method for detection of citrinin and the lactone and acid forms of monacolin K in red mold rice. | Journal of AOAC International 20060101 |
| Comparison between mevinolin and PTH action on MG63 osteoblast-like cells. | Biomedical sciences instrumentation 20060101 |
| Adherence and persistence with single-dosage form extended-release niacin/lovastatin compared with statins alone or in combination with extended-release niacin. | The Annals of pharmacotherapy 20060101 |
| Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis. | Arthritis research & therapy 20060101 |
| Safety issues with statin therapy. | Journal of the American Pharmacists Association : JAPhA 20060101 |
| Coronary heart disease policy models: a systematic review. | BMC public health 20060101 |
| A long-term study of dyslipidemia and dyslipoproteinemia in stable post-renal transplant patients. | Renal failure 20060101 |
| Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. | Journal of biomedicine & biotechnology 20060101 |
| Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1. | Retrovirology 20060101 |
| Statins, bugs and prophylaxis: intriguing possibilities. | Critical care (London, England) 20060101 |
| Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. | Chinese medicine 20060101 |
| Determination by chromatographic methods of selected medicines reducing the level of cholesterol. | Acta poloniae pharmaceutica 20060101 |
| Effect of Monascus purpureus-fermented rice on lipidemia and fatty liver in quail. | Research communications in molecular pathology and pharmacology 20060101 |
| [A short-term effect of lovastatin on lipoprotein metabolism in patients with cerebrovascular lesions concomitant with diabetes mellitus II type]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101 |
| Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. | The Journal of biological chemistry 20051216 |
| Implications from the Air Force/Texas Coronary Atherosclerosis Prevention Study for the Adult Treatment Panel III guidelines. | The American journal of cardiology 20051215 |
| Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051201 |
| Lovastatin stimulates p75 TNF receptor (TNFR2) expression in primary human endothelial cells. | International journal of molecular medicine 20051201 |
| Plasma clearance of lovastatin versus chinese red yeast rice in healthy volunteers. | Journal of alternative and complementary medicine (New York, N.Y.) 20051201 |
| Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results. | Arquivos de neuro-psiquiatria 20051201 |
| Extracts of Monascusus purpureus beyond statins--profile of efficacy and safety of the use of extracts of Monascus purpureus. | Chinese journal of integrative medicine 20051201 |
| [Fluvastatin-induced dermatomyositis]. | Annales de dermatologie et de venereologie 20051201 |
| Replication of Coxiella burnetii is inhibited in CHO K-1 cells treated with inhibitors of cholesterol metabolism. | Annals of the New York Academy of Sciences 20051201 |
| Optimal lipid modification: the rationale for combination therapy. | Vascular health and risk management 20051201 |
| Efficacy and safety of atorvastatin in South Asian patients with dyslipidemia: an open label noncomparative pilot study. | Vascular health and risk management 20051201 |
| Are statins being underdosed in clinical practice? Data from TACTICS-TIMI 18. | Critical pathways in cardiology 20051201 |
| Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: a proven reality. | Therapeutics and clinical risk management 20051201 |
| INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. | The EMBO journal 20051116 |
| Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein. | Journal of neuroscience research 20051115 |
| The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. | Current biology : CB 20051108 |
| The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells. | The Journal of surgical research 20051101 |
| Pregnancy outcomes after maternal exposure to simvastatin and lovastatin. | Birth defects research. Part A, Clinical and molecular teratology 20051101 |
| Optimal goals for statin use in patients with coronary artery disease. | Current opinion in cardiology 20051101 |
| PAF-receptor antagonists, lovastatin, and the PTK inhibitor genistein inhibit H2O2 secretion by macrophages cultured on oxidized-LDL matrices. | Journal of leukocyte biology 20051101 |
| Experience with statin use in patients with chronic hepatitis C infection. | The American journal of cardiology 20051101 |
| X-Hitting: an algorithm for novelty detection and dereplication by UV spectra of complex mixtures of natural products. | Analytical chemistry 20051101 |
| Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment. | Cellular and molecular life sciences : CMLS 20051101 |
| The effect of switching on compliance and persistence: the case of statin treatment. | The American journal of managed care 20051101 |
| Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. | International journal of clinical pharmacology and therapeutics 20051101 |
| Safety of statins: effects on muscle and the liver. | Cleveland Clinic journal of medicine 20051101 |
| The benefits of statin therapy--what questions remain? | Clinical cardiology 20051101 |
| Statins and fibrates for preventing melanoma. | The Cochrane database of systematic reviews 20051019 |
| Calmodulin binding to the small GTPase Ral requires isoprenylated Ral. | Biochemical and biophysical research communications 20051014 |
| Evaluation of the anti-HIV activity of statins. | AIDS (London, England) 20051014 |
| Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume aqueous extract in cholesterol fed rats. | Journal of ethnopharmacology 20051003 |
| Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells. | Brain research. Molecular brain research 20051003 |
| In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells. | Clinical immunology (Orlando, Fla.) 20051001 |
| Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. | European journal of clinical pharmacology 20051001 |
| Differential association between statin exposure and elevated levels of creatine kinase. | The Annals of pharmacotherapy 20051001 |
| Clinical and economic outcomes of conversion of simvastatin to lovastatin in a group-model health maintenance organization. | Journal of managed care pharmacy : JMCP 20051001 |
| Tobacco BY-2 cells expressing fission yeast cdc25 bypass a G2/M block on the cell cycle. | The Plant journal : for cell and molecular biology 20051001 |
| The association between RhoB and caspase-2: changes with lovastatin-induced apoptosis. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20051001 |
| Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001 |
| Grape fruit juice-drug interactions. | Pakistan journal of pharmaceutical sciences 20051001 |
| [Hypolipidemic treatment under special conditions: posttransplant and/or immunosuppressive therapy]. | Arquivos brasileiros de cardiologia 20051001 |
| Study on red fermented rice with high concentration of monacolin K and low concentration of citrinin. | International journal of food microbiology 20050915 |
| Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. | Journal of molecular biology 20050909 |
| Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin. | The American journal of cardiology 20050905 |
| Lovastatin inhibits the growth and survival pathway of phosphoinositide 3-kinase/protein kinase B in immortalized rat brain neuroblasts. | Journal of neurochemistry 20050901 |
| HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050901 |
| The pharmacological potential of mushrooms. | Evidence-based complementary and alternative medicine : eCAM 20050901 |
| Efficacy and safety of lovastatin therapy in adolescent girls with heterozygous familial hypercholesterolemia. | Pediatrics 20050901 |
| Lovastatin reduces nuclear factor kappaB activation induced by C-reactive protein in human vascular endothelial cells. | Biological & pharmaceutical bulletin 20050901 |
| Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells. | British journal of haematology 20050901 |
| Successful conversion of patients with hypercholesterolemia from a brand name to a generic cholesterol-lowering drug. | The American journal of managed care 20050901 |
| Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling. | Endocrine-related cancer 20050901 |
| Regulation of connexin expression after balloon injury: possible mechanisms for antiproliferative effect of statins. | American journal of hypertension 20050901 |
| Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. | British journal of cancer 20050808 |
| Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1. | The Journal of biological chemistry 20050805 |
| Lovastatin-induced PC-12 cell differentiation is associated with RhoA/RhoA kinase pathway inactivation. | Molecular and cellular neurosciences 20050801 |
| Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process. | European journal of clinical nutrition 20050801 |
| Lipoprotein-associated phospholipase A2 as a target of therapy. | Current opinion in lipidology 20050801 |
| Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8. | Basic & clinical pharmacology & toxicology 20050801 |
| The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, lovastatin (statin) ameliorates CCK-induced acute pancreatitis in rats. | Biological & pharmaceutical bulletin 20050801 |
| Evolutionary relationships among Aspergillus terreus isolates and their relatives. | Antonie van Leeuwenhoek 20050801 |
| Statin-induced blockade of prenylation alters nucleocytoplasmic shuttling of GTP-binding proteins gamma2 and beta2 and enhances their suppressive effect on glucocorticoid receptor transcriptional activity. | European journal of clinical investigation 20050801 |
| Polar body formation in Spisula oocytes: function of the peripheral aster. | The Biological bulletin 20050801 |
| [Effect of Laminaria japonica polysaccharides on lowing serum lipid and anti-atherosclerosis in hyperlipemia quails]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050801 |
| Natural insights for chemical biologists. | Nature chemical biology 20050801 |
| Risks of a nonprescription lovastatin. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715 |
| Association between short-term effectiveness of statins and long-term adherence to lipid-lowering therapy. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715 |
| Induction of macrophage elastase (MMP-12) gene expression by statins. | Journal of cellular physiology 20050701 |
| Direct comparison of dietary portfolio vs statin on C-reactive protein. | European journal of clinical nutrition 20050701 |
| Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction. | Journal of neurochemistry 20050701 |
| Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities. | Current opinion in cardiology 20050701 |
| Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings. | Preventing chronic disease 20050701 |
| Effects of cholesterol-lowering statins on the aqueous humor outflow pathway. | Investigative ophthalmology & visual science 20050701 |
| In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis. | European journal of endocrinology 20050701 |
| JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998). | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701 |
| Gestational exposure to lovastatin followed by cardiac malformation misclassified as holoprosencephaly. | The New England journal of medicine 20050630 |
| Degradation of HMG-CoA reductase in rat liver is cholesterol and ubiquitin independent. | FEBS letters 20050606 |
| Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. | Journal of lipid research 20050601 |
| Statin drugs and congenital anomalies. | American journal of medical genetics. Part A 20050601 |
| Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study). | The American journal of cardiology 20050601 |
| A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin. | Atherosclerosis 20050601 |
| The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells. | Journal of Korean medical science 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050601 |
| 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway. | Journal of chemical ecology 20050601 |
| A new paradigm of cardiovascular risk factor modification. | Vascular health and risk management 20050601 |
| PKCalpha is involved in phorbol ester TPA-mediated stabilization of p14ARF. | Biochemical and biophysical research communications 20050520 |
| Remote asymmetric induction in an intramolecular ionic Diels-Alder reaction: application to the total synthesis of (+)-dihydrocompactin. | Journal of the American Chemical Society 20050511 |
| HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma. | British journal of cancer 20050509 |
| Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells. | Carcinogenesis 20050501 |
| Hepatic uptake of the novel antifungal agent caspofungin. | Drug metabolism and disposition: the biological fate of chemicals 20050501 |
| The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells. | Journal of lipid research 20050501 |
| Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta. | Arteriosclerosis, thrombosis, and vascular biology 20050501 |
| Lovastatin alters the isoprenoid biosynthetic pathway in acute myelogenous leukemia cells in vivo. | Leukemia research 20050501 |
| Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects. | The American journal of cardiology 20050501 |
| Ascorbate depletion: a critical step in nickel carcinogenesis? | Environmental health perspectives 20050501 |
| A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. | Mayo Clinic proceedings 20050501 |
| National trends in statin use by coronary heart disease risk category. | PLoS medicine 20050501 |
| [Hypothyroidism and lovastatin-induced myositis]. | Anales de medicina interna (Madrid, Spain : 1984) 20050501 |
| Statins reduce connexin40 and connexin43 expression in atherosclerotic aorta of rabbits. | International journal of cardiology 20050428 |
| Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050426 |
| Frequency of myopathy in patients receiving lovastatin. | The American journal of cardiology 20050415 |
| Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells. | Biochimica et biophysica acta 20050415 |
| Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. | Drug metabolism and disposition: the biological fate of chemicals 20050401 |
| Projected coronary heart disease risk benefit with ezetimibe. | Atherosclerosis 20050401 |
| Measurement of saturable and non-saturable components of anandamide uptake into P19 embryonic carcinoma cells in the presence of fatty acid-free bovine serum albumin. | Chemistry and physics of lipids 20050401 |
| Post-translational processing of beta-secretase in Alzheimer's disease. | Proteomics 20050401 |
| The effect of lovastatin and thioridazine on the degradation of cocaine in human serum in vitro. | Therapeutic drug monitoring 20050401 |
| Heart failure and statins--why do we need a clinical trial? | Zeitschrift fur Kardiologie 20050401 |
| Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes. | Experimental dermatology 20050401 |
| [Effects of fosmidomycin and lovastatin treatment on taxol biosynthesis in suspension culture cells of Taxus chinensis]. | Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050401 |
| Lovastatin-induced apoptosis in human melanoma cell lines. | Melanoma research 20050401 |
| Targeted therapy in multiple myeloma. | Cancer control : journal of the Moffitt Cancer Center 20050401 |
| A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense. | American journal of respiratory and critical care medicine 20050315 |
| The regulation of beta-secretase by cholesterol and statins in Alzheimer's disease. | Journal of the neurological sciences 20050315 |
| Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050315 |
| Pellet morphology, culture rheology and lovastatin production in cultures of Aspergillus terreus. | Journal of biotechnology 20050302 |
| Progesterone-receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in vitro. | Biology of reproduction 20050301 |
| A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix. | European journal of cancer (Oxford, England : 1990) 20050301 |
| FDA advisers vote against nonprescription lovastatin. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050301 |
| Is atorvastatin more appropriate to use in combination with niacin than simvastatin in patients with the metabolic syndrome? | American heart journal 20050301 |
| Lovastatin enhances in vitro radiation-induced apoptosis of rat B-cell lymphoma cells. | Journal of experimental & clinical cancer research : CR 20050301 |
| A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. | The AAPS journal 20050301 |
| Ongoing clinical trials of the pleiotropic effects of statins. | Vascular health and risk management 20050301 |
| Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4. | Therapeutics and clinical risk management 20050301 |
| Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. | Journal of immunology (Baltimore, Md. : 1950) 20050215 |
| [The 'healthy' patient with hypercholesterolemia]. | Medizinische Klinik (Munich, Germany : 1983) 20050215 |
| Statin-inhibited endothelial permeability could be associated with its effect on PECAM-1 in endothelial cells. | FEBS letters 20050214 |
| Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex. | The Journal of pharmacology and experimental therapeutics 20050201 |
| Statins as coronary vasodilators in isolated bovine coronary arteries--involvement of PGI2 and NO. | Prostaglandins, leukotrienes, and essential fatty acids 20050201 |
| Differential effects of RhoA signaling on anticancer agent-induced cell death. | Oncology reports 20050201 |
| Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. | Fundamental & clinical pharmacology 20050201 |
| Existence of a clinically relevant interaction between clopidogrel and HMG-CoA reductase inhibitors? Re-evaluating the evidence. | Basic & clinical pharmacology & toxicology 20050201 |
| Gender-specific effects of estrogen receptor alpha gene haplotype on high-density lipoprotein cholesterol response to atorvastatin: interaction with apolipoprotein AI gene polymorphism. | Atherosclerosis 20050201 |
| Lovastatin compromises C-reactive protein induced endothelial dysfunction including altered expression of cell adhesion molecules and increased monocyte recruitment. | Atherosclerosis 20050201 |
| Patients with elevated baseline liver enzymes do not have higher frequency of hepatotoxicity from lovastatin than those with normal baseline liver enzymes. | The American journal of the medical sciences 20050201 |
| Statins and osteoporosis: a clinical review. | Pharmacotherapy 20050201 |
| Simultaneous determination of farnesyl and geranylgeranyl pyrophosphate levels in cultured cells. | Analytical biochemistry 20050101 |
| Factors regulating macrophage endocytosis of nanoparticles: implications for targeted magnetic resonance plaque imaging. | Atherosclerosis 20050101 |
| Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha). | Biochemical pharmacology 20050101 |
| Examination of 209 drugs for inhibition of cytochrome P450 2C8. | Journal of clinical pharmacology 20050101 |
| Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice. | Journal of cardiovascular pharmacology 20050101 |
| Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo. | Clinical pharmacology and therapeutics 20050101 |
| Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. | PLoS medicine 20050101 |
| Endogenous cytokinin oscillations control cell cycle progression of tobacco BY-2 cells. | Plant biology (Stuttgart, Germany) 20050101 |
| Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction. | International journal of cardiology 20050101 |
| Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS. | Lipids in health and disease 20050101 |
| Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR mice. | The British journal of nutrition 20050101 |
| Parallel capillary electrophoresis for the quantitative screening of fermentation broths containing natural products. | Metabolic engineering 20050101 |
| Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases? | Arthritis research & therapy 20050101 |
| Human macrophages limit oxidation products in low density lipoprotein. | Lipids in health and disease 20050101 |
| Cost effectiveness of treating low HDL-cholesterol in the primary prevention of coronary heart disease. | PharmacoEconomics 20050101 |
| [Effects of withdrawal of statins on nitric oxide production in vascular endothelial cells]. | Zhonghua nei ke za zhi 20050101 |
| The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393]. | BMC medicine 20050101 |
| Renewed interest in lovastatin following launch of Lovachol. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101 |
| Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK. | Molecular and cellular biochemistry 20050101 |
| The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst. | Journal of negative results in biomedicine 20050101 |
| Effect of cholesterol lowering and cardiovascular risk factors on the progression of aortoiliac arteriosclerosis: a quantitative cineangiography study. | Angiology 20050101 |
| [Protective effects of Lovastatin on early diabetic renal tissue and the possible mechanism]. | Wei sheng yan jiu = Journal of hygiene research 20050101 |
| Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. | Clinical pharmacokinetics 20050101 |
| The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kappa B transcriptional activity in models of rheumatoid arthritis. | Arthritis research & therapy 20050101 |
| Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study. | Current controlled trials in cardiovascular medicine 20050101 |
| Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study. | Cardiovascular diabetology 20050101 |
| [Prevalence of nonmevalonate and mevalonate pathways for isoprenoid biosynthesis among bacteria of different systematic groups]. | Mikrobiologiia 20050101 |
| Statins research unfinished saga: desirability versus feasibility. | Cardiovascular diabetology 20050101 |
| An association study of 43 SNPs in 16 candidate genes with atorvastatin response. | The pharmacogenomics journal 20050101 |
| [Isoprenoid pigments in representatives of the family Microbacteriaceae]. | Mikrobiologiia 20050101 |
| Relationship between lipophilicity of BCS class III and IV drugs and the functional activity of peroral absorption enhancers. | Farmaco (Societa chimica italiana : 1989) 20050101 |
| Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre. | Przeglad lekarski 20050101 |
| Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers. | Farmaco (Societa chimica italiana : 1989) 20050101 |
| Time as a variable with niacin extended-release/lovastatin vs. atorvastatin and simvastatin. | Preventive cardiology 20050101 |
| Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation. | Preventive cardiology 20050101 |
| Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease. | Lipids in health and disease 20050101 |
| [Impact of dietotherapy with enterosorbent of marine origin on the indices of mineral and lipid metabolism for patients suffering from kidney diseases]. | Voprosy pitaniia 20050101 |
| Cost-effectiveness of rosuvastatin compared with other statins from a managed care perspective. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101 |
| Pharmacist intervention in safe and effective conversion of brand to generic drugs. | Journal of managed care pharmacy : JMCP 20050101 |
| Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation. | Journal of neuroinflammation 20050101 |
| [Interactions in solution between cyclodextrins and statins]. | Acta pharmaceutica Hungarica 20050101 |
| Altered mitochondrial function and cholesterol synthesis influences protein synthesis in extended HepG2 spheroid cultures. | Archives of biochemistry and biophysics 20041215 |
| The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells. | Free radical biology & medicine 20041215 |
| Mechanistic and epidemiologic considerations in the evaluation of adverse birth outcomes following gestational exposure to statins. | American journal of medical genetics. Part A 20041215 |
| Statin-associated exacerbation of myasthenia gravis. | Neurology 20041214 |
| HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPbeta. | Experimental cell research 20041210 |
| Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression. | Journal of lipid research 20041201 |
| Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. | Arteriosclerosis, thrombosis, and vascular biology 20041201 |
| Niacin therapy in atherosclerosis. | Current opinion in lipidology 20041201 |
| Lovastatin potentiates antitumor effects of saquinavir against human lymphoma cells. | Oncology reports 20041201 |
| Hypolipidemic drugs can change the composition of rat brain lipids. | The Tohoku journal of experimental medicine 20041201 |
| [Effects of lovastatin on renal function and expression of phosphorylating-p38 mitogen-activated protein kinase in experimental diabetic nephropathy in rats]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20041201 |
| Atazanavir for the treatment of human immunodeficiency virus infection. | Pharmacotherapy 20041201 |
| Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults. | The American journal of medicine 20041201 |
| Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men. | Journal of women's health (2002) 20041201 |
| [Therapeutic compliance in the prevention of primary cardiovascular diseases with lovastatine. PRELOVAS study]. | Medicina clinica 20041120 |
| Modified mutation method for screening low citrinin-producing strains of Monascus purpureus on rice culture. | Journal of agricultural and food chemistry 20041117 |
| Fluvastatin and lovastatin but not pravastatin induce neuroglial differentiation in human mesenchymal stem cells. | Journal of cellular biochemistry 20041115 |
| A Consumer Use Study of Over-The-Counter lovastatin (CUSTOM). | The American journal of cardiology 20041115 |
| Over-the-counter statin drug. | The American journal of cardiology 20041115 |
| Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. | The Journal of biological chemistry 20041112 |
| Recurrent acute pancreatitis possibly induced by atorvastatin and rosuvastatin. Is statin induced pancreatitis a class effect? | JOP : Journal of the pancreas 20041110 |
| Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. | Circulation 20041109 |
| Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo. | The Journal of biological chemistry 20041105 |
| Consumer behavior in the setting of over-the-counter statin availability: lessons from the consumer use study of OTC Mevacor. | The American journal of cardiology 20041104 |
| Lovastatin exacerbates atypical absence seizures with only minimal effects on brain sterols. | Journal of lipid research 20041101 |
| Statin inhibition of Fc receptor-mediated phagocytosis by macrophages is modulated by cell activation and cholesterol. | Arteriosclerosis, thrombosis, and vascular biology 20041101 |
| Bis[3-(4'-substituted phenyl)prop-2-ene]disulfides as a new class of antihyperlipidemic compounds. | Bioorganic & medicinal chemistry letters 20041101 |
| Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1. | Journal of virology 20041101 |
| Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin. | Cardiovascular research 20041101 |
| OTC status for low-dose lovastatin would have widespread implications. | Managed care (Langhorne, Pa.) 20041101 |
| Lovastatin modulation of microglial activation via suppression of functional CD40 expression. | Journal of neuroscience research 20041015 |
| Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism. | Carcinogenesis 20041001 |
| Management of hypertriglyceridemia in patients receiving interferon for malignant melanoma. | The Annals of pharmacotherapy 20041001 |
| Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment. | Brain research 20041001 |
| Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits. | Clinical nutrition (Edinburgh, Scotland) 20041001 |
| C-reactive protein-induced expression of CD40-CD40L and the effect of lovastatin and fenofibrate on it in human vascular endothelial cells. | Biological & pharmaceutical bulletin 20041001 |
| Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis. | Fertility and sterility 20041001 |
| Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1. | PLoS medicine 20041001 |
| Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. 1976. | Atherosclerosis. Supplements 20041001 |
| Therapeutic effects of ml-236B in primary hypercholesterolemia. 1980. | Atherosclerosis. Supplements 20041001 |
| Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia. 1981. | Atherosclerosis. Supplements 20041001 |
| Lowering plasma cholesterol by raising ldl receptors. 1981. | Atherosclerosis. Supplements 20041001 |
| Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholeserolemia heterozygotes. 1983. | Atherosclerosis. Supplements 20041001 |
| Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. | Neurochemical research 20041001 |
| [Study on space flight-mutants of Monascus purpureus using Random Amplified Polymorphic DNA]. | Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20041001 |
| Dietary palmitic acid influences LDL-mediated lymphocyte proliferation differently to other mono- and polyunsaturated fatty acids in rats. | Diabetes, nutrition & metabolism 20041001 |
| The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion-mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase. | Blood 20040915 |
| Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells. | Blood 20040915 |
| Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis. | Cancer research 20040915 |
| Development of methodologies based on HPLC and Raman spectroscopy for monitoring the stability of lovastatin in solid state in the presence of gallic acid. | Journal of pharmaceutical and biomedical analysis 20040903 |
| Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20040903 |
| Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38. | The Journal of investigative dermatology 20040901 |
| Development of an acetylene black-dihexadecyl hydrogen phosphate composite-modified glassy-carbon electrode, and its application in the determination of lovastatin in dosage drug forms. | Analytical and bioanalytical chemistry 20040901 |
| Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin. | Journal of molecular and cellular cardiology 20040901 |
| [Vastatins in atherosclerosis prevention. Current data]. | Arquivos brasileiros de cardiologia 20040901 |
| Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers. | Current medical research and opinion 20040901 |
| Oral administration of pravastatin reduces egg cholesterol but not plasma cholesterol in laying hens. | Poultry science 20040901 |
| New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum. | Journal of natural products 20040901 |
| Rosuvastatin in the management of hyperlipidemia. | Clinical therapeutics 20040901 |
| Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. | Circulation research 20040820 |
| Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins. | Circulation 20040817 |
| Statins inhibit HIV-1 infection by down-regulating Rho activity. | The Journal of experimental medicine 20040816 |
| Ionizing radiation-induced E-selectin gene expression and tumor cell adhesion is inhibited by lovastatin and all-trans retinoic acid. | Carcinogenesis 20040801 |
| Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin. | Blood 20040801 |
| Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. | American journal of physiology. Heart and circulatory physiology 20040801 |
| Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20040801 |
| Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Cholesterol (and cardiovascular risk) in adolescence. | Current opinion in pediatrics 20040801 |
| Safety and compliance with once-daily niacin extended-release/lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment (IMPACT) study. | The American journal of cardiology 20040801 |
| Lipid-lowering response to statins is affected by CYP3A5 polymorphism. | Pharmacogenetics 20040801 |
| Focal adhesion kinase mediates endothelin-induced cyclin D3 expression in rat cultured astrocytes. | Journal of neurochemistry 20040801 |
| [Effects of lovastatin on cell cycle distribution in MCF-7 cells transfected with BRCA1]. | Ai zheng = Aizheng = Chinese journal of cancer 20040801 |
| The hypolipidemic compound cetaben induces changes in Golgi morphology and vesicle movement. | Histochemistry and cell biology 20040801 |
| The multifunctional role of fibroblasts during wound healing in Hirudo medicinalis (Annelida, Hirudinea). | Biology of the cell 20040801 |
| Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia. | International journal of clinical practice 20040801 |
| Lipid rafts mediate the synaptic localization of alpha-synuclein. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728 |
| Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis. | Biochemical and biophysical research communications 20040716 |
| Evaluation of hesperetin 7-O-lauryl ether as lipid-lowering agent in high-cholesterol-fed rats. | Bioorganic & medicinal chemistry 20040701 |
| Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. | Journal of neuroscience research 20040701 |
| Differential effects of simvastatin on mesangial cells. | Kidney international 20040701 |
| Genetically modified mice and their use in developing therapeutic strategies for prostate cancer. | The Journal of urology 20040701 |
| Extended-release niacin/lovastatin: the first combination product for dyslipidemia. | Expert review of cardiovascular therapy 20040701 |
| Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. | Experimental biology and medicine (Maywood, N.J.) 20040701 |
| Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors. | Biochemical pharmacology 20040615 |
| Compactin-a review. | Applied microbiology and biotechnology 20040601 |
| Maintenance of G1 checkpoint controls in telomerase-immortalized endothelial cells. | Cell cycle (Georgetown, Tex.) 20040601 |
| Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS. | Analytical biochemistry 20040601 |
| Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. | Protein science : a publication of the Protein Society 20040601 |
| Extended-release niacin for modifying the lipoprotein profile. | Expert opinion on pharmacotherapy 20040601 |
| Multisite inhibition by phenylacetate of PC-3 cell growth. | Anti-cancer drugs 20040601 |
| Overdependence on the host-an Achilles' heel of HCV? | Hepatology (Baltimore, Md.) 20040601 |
| Statins: novel additions to the dermatologic arsenal? | Experimental dermatology 20040601 |
| Effects of ezetimibe on the pharmacodynamics and pharmacokinetics of lovastatin. | Current medical research and opinion 20040601 |
| [In vitro effects of mevastatin on the proliferation and apoptosis in human multiple myeloma cell line U266]. | Zhongguo shi yan xue ye xue za zhi 20040601 |
| Metaanalysis of statins and survival in de novo cardiac transplantation. | Transplantation proceedings 20040601 |
| The role of maternal toxicity in lovastatin-induced developmental toxicity. | Birth defects research. Part B, Developmental and reproductive toxicology 20040601 |
| Molecular basis of ML-236B production in the high-producing mutant No. 41520 of Penicillium citrinum. | The Journal of general and applied microbiology 20040601 |
| Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis. | Archives of internal medicine 20040524 |
| Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain. | Bioorganic & medicinal chemistry letters 20040517 |
| Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis. | Metabolism: clinical and experimental 20040501 |
| Class-specific pro-apoptotic effect of statins on human vascular endothelial cells. | Zeitschrift fur Kardiologie 20040501 |
| Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. | Radiation research 20040501 |
| Statins and liver toxicity: a meta-analysis. | Pharmacotherapy 20040501 |
| Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice. | British journal of cancer 20040419 |
| Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages. | Biochemical and biophysical research communications 20040409 |
| Cyclin E deregulation alters the biologic properties of ovarian cancer cells. | Oncogene 20040408 |
| Professional athletes suffering from familial hypercholesterolaemia rarely tolerate statin treatment because of muscular problems. | British journal of clinical pharmacology 20040401 |
| Psychological and cognitive function: predictors of adherence with cholesterol lowering treatment. | Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 20040401 |
| Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells. | Journal of neurochemistry 20040401 |
| Depletion of cellular cholesterol and lipid rafts increases shedding of CD30. | Journal of immunology (Baltimore, Md. : 1950) 20040401 |
| LaeA, a regulator of secondary metabolism in Aspergillus spp. | Eukaryotic cell 20040401 |
| Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells. | Biochimica et biophysica acta 20040322 |
| Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling. | Biochemical and biophysical research communications 20040312 |
| Rational elimination of Aspergillus terreus sulochrin production. | Journal of biotechnology 20040304 |
| Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris. | Planta 20040301 |
| Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study. | Brain : a journal of neurology 20040301 |
| Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism. | Arteriosclerosis, thrombosis, and vascular biology 20040301 |
| Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels. | The Plant journal : for cell and molecular biology 20040301 |
| De novo biosynthesis and radiolabeling of mammalian digitalis-like factors. | Clinical chemistry 20040301 |
| Eggplant (Solanum melongena) extract does not alter serum lipid levels. | Arquivos brasileiros de cardiologia 20040301 |
| Association of dyslipidemia and effects of statins on nonmacrovascular diseases. | Clinical therapeutics 20040301 |
| Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. | Life sciences 20040213 |
| Statin use and cancer risk in the General Practice Research Database. | British journal of cancer 20040209 |
| Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth. | The Journal of biological chemistry 20040206 |
| Hormonal changes with cholesterol reduction: a double-blind pilot study. | Journal of clinical pharmacy and therapeutics 20040201 |
| Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040201 |
| Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature. | Pharmacotherapy 20040201 |
| Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies. | European journal of medical research 20040126 |
| Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication. | Biochemical and biophysical research communications 20040123 |
| Statins potentiate caspase-3 activity in immortalized murine neurons. | Neuroscience letters 20040123 |
| Influence of lipid lowering fibrates on P-glycoprotein activity in vitro. | Biochemical pharmacology 20040115 |
| Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression. | Biochemical pharmacology 20040115 |
| Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy. | Journal of immunology (Baltimore, Md. : 1950) 20040115 |
| Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. | Neuroscience letters 20040109 |
| Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101 |
| Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-13C]glucose. | Plant physiology 20040101 |
| Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development. | The Plant cell 20040101 |
| Differential effects of lipid-lowering agents on human cholinesterases. | Clinical biochemistry 20040101 |
| Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer. | Breast cancer research : BCR 20040101 |
| Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells. | Basic research in cardiology 20040101 |
| Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects. | The American journal of cardiology 20040101 |
| Allocation of resources between smoking cessation methods and lovastatin treatment of hypercholesterolaemia: based on cost effectiveness and the social welfare function. | PharmacoEconomics 20040101 |
| Lovastatin inhibits its own synthesis in Aspergillus terreus. | Journal of industrial microbiology & biotechnology 20040101 |
| Efficacy of once-daily extended-release lovastatin as compared to immediate-release lovastatin in patients with hypercholesterolemia. | Current medical research and opinion 20040101 |
| Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. | Lipids in health and disease 20040101 |
| [X-linked adrenoleukodystrophy (ALD)]. | Nihon rinsho. Japanese journal of clinical medicine 20040101 |
| Gene transfer into human hepatoma cells by receptor-associated protein/polylysine conjugates. | Bioconjugate chemistry 20040101 |
| Down-regulating effect of nicotine on connexin43 gap junctions in human umbilical vein endothelial cells is attenuated by statins. | European journal of cell biology 20040101 |
| Rising statin use and effect on ischemic stroke outcome. | BMC medicine 20040101 |
| C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases. | Medical hypotheses 20040101 |
| Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation. | BMC cell biology 20040101 |
| Effect of Lovastatin on lipid peroxidation and total antioxidant concentrations in hemodialysis patients. | Lipids in health and disease 20040101 |
| The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells. | BMC cardiovascular disorders 20040101 |
| Assessing compliance of cardiologists with the national cholesterol education program (NCEP) III guidelines in an ambulatory care setting. | Lipids in health and disease 20040101 |
| Lichenoid drug eruption with HMG-CoA reductase inhibitors (fluvastatin and lovastatin). | Acta dermato-venereologica 20040101 |
| DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells. | BMC cancer 20040101 |
| Statins rise cytoplasmic calcium level [Ca2+]i in cultured endothelial cells. | Polish journal of pharmacology 20040101 |
| [Idiopathic membranous nephropathy associated with anti-calcineurin toxicity. Prognosis and other immunosuppressive treatments]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101 |
| Effect of Nandrolone Decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients. | Lipids in health and disease 20040101 |
| Cost-effectiveness analysis of simvastatin and lovastatin/extended- release niacin to achieve LDL and HDL goal using NHANES data. | Journal of managed care pharmacy : JMCP 20040101 |
| Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci. | Anticancer research 20040101 |
| Mevastatin-induced apoptosis and growth suppression in U266 myeloma cells. | Anticancer research 20040101 |
| Role of isoprenoids in cytoskeleton integrity and albumin endocytosis by opossum kidney cells. | Nephron. Experimental nephrology 20040101 |
| Pharmacokinetic study on lovastatin sustained-release tablet and sustained-release capsule in Beagal dogs. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
| Low-molecular-weight cyclin E: the missing link between biology and clinical outcome. | Breast cancer research : BCR 20040101 |
| Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor. | Neuroscience 20040101 |
| Interactions between grapefruit juice and cardiovascular drugs. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101 |
| Effect of time of administration on cholesterol-lowering by psyllium: a randomized cross-over study in normocholesterolemic or slightly hypercholesterolemic subjects. | Nutrition journal 20040101 |
| [Lovastatin effect on ergosterol production and growth of Tolypocladium inflatum 106]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101 |
| The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia. | Lipids in health and disease 20040101 |
| Influence of lovastatin on BCL-2 and BAX expression by plasma cells and T lymphocytes in short-term cultures of multiple myeloma bone marrow mononuclear cells. | Polish journal of pharmacology 20040101 |
| Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. | Genome biology 20040101 |
| The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases. | Genome biology 20040101 |
| Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts. | Genetics in medicine : official journal of the American College of Medical Genetics 20040101 |
| Effect of 3,4-di(OH)-cinnamate synthetic derivative on plasma and hepatic cholesterol level and antioxidant enzyme activities in high cholesterol-fed rats. | Journal of biochemical and molecular toxicology 20040101 |
| Cytoskeletal actin degradation induced by lovastatin in cardiomyocytes is mediated through caspase-2. | Cell biology international 20040101 |
| The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481]. | Cardiovascular diabetology 20040101 |
| [Thrombocytic hemostasis in hypertensive patients with metabolic syndrome and its correction with lovastatin]. | Klinicheskaia meditsina 20040101 |
| Anti-Plasmodium activity of ceramide analogs. | Malaria journal 20040101 |
| Lipid metabolism in zebrafish. | Methods in cell biology 20040101 |
| [Mevastatin induced apoptosis in U266 human myeloma cell line]. | Magyar onkologia 20040101 |
| KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2. | Clinical & experimental metastasis 20040101 |
| [Screening of natural compounds with hypolipidemic activity]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101 |
| [Estimation of the efficacy of screened natural hypolipidemic compounds in a model of rabbit hypercholesterolemia]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101 |
| Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells. | Cancer letters 20031230 |
| Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. | Proceedings of the National Academy of Sciences of the United States of America 20031223 |
| Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death with the apoptotic component blunted by both caspase-2 and caspase-3 inhibitors. | Toxicology and applied pharmacology 20031215 |
| Statins induce suppressor of cytokine signaling-3 in macrophages. | FEBS letters 20031204 |
| Two derivative spectrophotometric methods for the simultaneous determination of lovastatin combined with three antioxidants. | Journal of pharmaceutical and biomedical analysis 20031204 |
| Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20031201 |
| Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade. | American journal of physiology. Renal physiology 20031201 |
| Methyl palmitate: a novel product of the Medfly (Ceratitis capitata) corpus allatum. | Insect biochemistry and molecular biology 20031201 |
| Chinese red rice-induced myopathy. | Southern medical journal 20031201 |
| [Ezetimibe: from pharmacology to clinical trials]. | Annales d'endocrinologie 20031201 |
| Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | British journal of cancer 20031117 |
| Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031115 |
| Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development. | Circulation research 20031114 |
| Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial. | Circulation 20031111 |
| Effects of statins on platelet inhibition by a high loading dose of clopidogrel. | Circulation 20031104 |
| Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels. | Blood 20031101 |
| Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells. | Journal of cancer research and clinical oncology 20031101 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the lobster mandibular organ: regulation by the eyestalk. | General and comparative endocrinology 20031101 |
| Effects of cholesterol-lowering foods versus lovastatin on serum lipids and C-reactive protein. | Current atherosclerosis reports 20031101 |
| HMG-CoA reductase inhibition reduces the proinflammatory activation of human vascular smooth muscle cells by the terminal complement factor C5b-9. | Basic research in cardiology 20031101 |
| FK506 potentiates NGF-induced neurite outgrowth via the Ras/Raf/MAP kinase pathway. | British journal of pharmacology 20031101 |
| Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. | Free radical biology & medicine 20031101 |
| Effect of HMG-CoA reductase inhibitors on reduction of panel reactivity. | Transplantation proceedings 20031101 |
| Improvement of monacolin K, gamma-aminobutyric acid and citrinin production ratio as a function of environmental conditions of Monascus purpureus NTU 601. | Journal of industrial microbiology & biotechnology 20031101 |
| Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20031101 |
| Bioconversion of compactin into pravastatin by Streptomyces sp. | Biotechnology letters 20031101 |
| A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d. | Clinical therapeutics 20031101 |
| p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases. | The Journal of biological chemistry 20031031 |
| Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells. | British journal of cancer 20031020 |
| Inhibition of lysophosphatidic acid-induced RhoA activation and tumor cell invasion by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. | International journal of oncology 20031001 |
| Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study. | European heart journal 20031001 |
| Protective effects of lovastatin on vascular endothelium injured by low density lipoprotein. | Acta pharmacologica Sinica 20031001 |
| The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro. | Anti-cancer drugs 20031001 |
| Lovastatin inhibits adipogenic and stimulates osteogenic differentiation by suppressing PPARgamma2 and increasing Cbfa1/Runx2 expression in bone marrow mesenchymal cell cultures. | Bone 20031001 |
| Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase lower fecundity in the German cockroach: correlation between the effects on fecundity in vivo with the inhibition of enzymatic activity in embryo cells. | Pest management science 20031001 |
| The mevalonate synthesis pathway as a therapeutic target in cancer. | Clinical orthopaedics and related research 20031001 |
| Statins differentially regulate vascular endothelial growth factor synthesis in endothelial and vascular smooth muscle cells. | Atherosclerosis 20031001 |
| All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells. | Atherosclerosis 20031001 |
| Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans. | Medical mycology 20031001 |
| [Effect of space flight on yield of Monascus purpureus]. | Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20031001 |
| Cholesterol oxidase and the hydroxymethylglutaryl coenzyme A reductase inhibitor mevinolin perturb endocytic trafficking in cultured vascular smooth muscle cells. | Journal of submicroscopic cytology and pathology 20031001 |
| Small-molecule cyclin-dependent kinase modulators. | Oncogene 20030929 |
| cDNA cloning and gene expression analysis of human myo-inositol 1-phosphate synthase. | Archives of biochemistry and biophysics 20030915 |
| Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3. | Biochemical pharmacology 20030915 |
| Cholesterol requirement of hepatitis B surface antigen (HBsAg) secretion. | Virology 20030915 |
| Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). | The Journal of biological chemistry 20030905 |
| Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice. | Neurobiology of aging 20030901 |
| Inhibition of Rho family GTPases results in increased TNF-alpha production after lipopolysaccharide exposure. | Journal of immunology (Baltimore, Md. : 1950) 20030901 |
| Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. | Endocrinology 20030901 |
| Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. | Basic research in cardiology 20030901 |
| Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery. | Pharmacology & toxicology 20030901 |
| Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. | Cardiovascular research 20030901 |
| Statins differ in their ability to block NF-kappaB activation in human blood monocytes. | International journal of clinical pharmacology and therapeutics 20030901 |
| What's new in lipid management? | Pharmacotherapy 20030901 |
| Inhibition of lovastatin on proliferation and expression of proinflammatory cytokines in cultured human glomerular mesangial cells. | Chinese medical journal 20030901 |
| Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease. | Pharmacopsychiatry 20030901 |
| Increased expression of plasminogen activator inhibitor-1 by mediators of the acute phase response: a potential progenitor of vasculopathy in hypertensives. | Hypertension research : official journal of the Japanese Society of Hypertension 20030901 |
| Chronic pancreatitis. | Current opinion in gastroenterology 20030901 |
| Transport mechanism for lovastatin acid in bovine kidney NBL-1 cells: kinetic evidences imply involvement of monocarboxylate transporter 4. | International journal of pharmaceutics 20030827 |
| Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. | Circulation 20030826 |
| Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815 |
| Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity. | Neurochemistry international 20030801 |
| [Cholesterol-reducing medications-a new therapeutic option for multiple sclerosis? Statins as immunomodulators]. | Der Nervenarzt 20030801 |
| [Statin-induced Parkinson's-syndrome. Reader's letter on the article by J. Finsterer in 'Der Nervenarzt' (2003) 74:115-122]. | Der Nervenarzt 20030801 |
| Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females. | Biochemical pharmacology 20030801 |
| Simvastatin. | Acta crystallographica. Section C, Crystal structure communications 20030801 |
| HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells. | Atherosclerosis 20030801 |
| Mevastatin suppresses lipopolysaccharide-induced Rac activation in the human monocyte cell line THP-1. | Surgery 20030801 |
| Lovastatin causes sensitization of HeLa cells to ionizing radiation-induced apoptosis by the abrogation of G2 blockage. | International journal of radiation biology 20030801 |
| Effect of red mold rice supplements on serum and egg yolk cholesterol levels of laying hens. | Journal of agricultural and food chemistry 20030730 |
| Identifying the factors and signal pathways necessary for anchorage-independent growth of Ha-ras oncogene-transformed NIH/3T3 cells. | Life sciences 20030725 |
| Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin. | Biochemical and biophysical research communications 20030725 |
| Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. | JAMA 20030723 |
| Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. | The Journal of biological chemistry 20030718 |
| Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells. | Molecular vision 20030717 |
| Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells. | The Journal of biological chemistry 20030711 |
| Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin. | Chemical communications (Cambridge, England) 20030707 |
| Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells. | International journal of oncology 20030701 |
| Mechanism of simvastatin on induction of heat shock protein in osteoblasts. | Archives of biochemistry and biophysics 20030701 |
| Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. | Nature reviews. Drug discovery 20030701 |
| Statins sentence thyroid cancer cells to death rho. | The Journal of clinical endocrinology and metabolism 20030701 |
| Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells. | The Journal of clinical endocrinology and metabolism 20030701 |
| Therapeutic implications of recent ATP III guidelines and the important role of combination therapy in total dyslipidemia management. | Current opinion in cardiology 20030701 |
| Statin-associated memory loss: analysis of 60 case reports and review of the literature. | Pharmacotherapy 20030701 |
| [Effect of lovastatin on the expression of IkappaBalpha and cell-cycle regulating protein in MCF-7 cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20030701 |
| Increase in cholesterol and cholesterol oxidation products, and role of cholesterol oxidation products in kainate-induced neuronal injury. | Brain pathology (Zurich, Switzerland) 20030701 |
| Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis. | Lipids 20030701 |
| [Efficacy and safety of combined statin-fenofibrates therapy compared with monotherapy in patients with mixed hyperlipidemia and high risk of coronary heart disease]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030701 |
| Biochemical studies on marine fish oil part-I: effects of fish oil and lipid lowering drugs on HDL/LDL cholesterol levels. | Pakistan journal of pharmaceutical sciences 20030701 |
| Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. | BMJ (Clinical research ed.) 20030628 |
| Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients. | Neurology 20030624 |
| Of cancer and cholesterol: studies elucidate anticancer mechanisms of statins. | Journal of the National Cancer Institute 20030618 |
| Monoterpene regulation of Ras and Ras-related protein expression. | Journal of lipid research 20030601 |
| Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits. | Journal of ethnopharmacology 20030601 |
| Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes. | Diabetes care 20030601 |
| Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control. | Journal of insect physiology 20030601 |
| Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. | Clinical pharmacology and therapeutics 20030601 |
| Collision-induced dissociation of the negative ions of simvastatin hydroxy acid and related species. | Journal of mass spectrometry : JMS 20030601 |
| Therapeutic potential of lovastatin in multiple sclerosis. | Journal of neurology 20030601 |
| Hypolipidemic and anti-atherogenic effects of long-term Cholestin (Monascus purpureus-fermented rice, red yeast rice) in cholesterol fed rabbits. | The Journal of nutritional biochemistry 20030601 |
| Current perspectives on statins. | Journal of the Indian Medical Association 20030601 |
| Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase. | The Journal of biological chemistry 20030530 |
| Activation of insulin-like growth factor II signaling by mutant type p53: physiological implications for potentiation of IGF-II signaling by p53 mutant 249. | Molecular and cellular endocrinology 20030530 |
| Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionization tandem mass spectrometry. | Journal of chromatography. A 20030523 |
| Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK). | The Journal of biological chemistry 20030516 |
| HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes. | Circulation research 20030516 |
| Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. | Blood 20030501 |
| Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501 |
| Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages. | Arteriosclerosis, thrombosis, and vascular biology 20030501 |
| Effect of HMG-CoA reductase inhibitors on proliferation and protein synthesis by rat hepatic stellate cells. | Journal of hepatology 20030501 |
| Treating dyslipidemic patients with lipid-modifying and combination therapies. | Pharmacotherapy 20030501 |
| Acute pancreatitis due to pravastatin therapy. | JOP : Journal of the pancreas 20030501 |
| Three new drugs for hyperlipidemia. | Connecticut medicine 20030501 |
| Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen. | Cellular immunology 20030501 |
| Lovastatin inhibits bone marrow-derived dendritic cell maturation and upregulates proinflammatory cytokine production. | Cellular immunology 20030501 |
| Ezetimibe: a novel option for lowering cholesterol. | Expert review of cardiovascular therapy 20030501 |
| Inhibition of pancreatic stellate cell activation by the hydroxymethylglutaryl coenzyme A reductase inhibitor lovastatin. | Biochemical pharmacology 20030415 |
| Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415 |
| High-density lipoprotein subpopulations in pathologic conditions. | The American journal of cardiology 20030403 |
| Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training. | American journal of physiology. Heart and circulatory physiology 20030401 |
| A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis. | Nature genetics 20030401 |
| Residual effects of lovastatin and simvastatin on urinary mevalonate excretions in patients with familial hypercholesterolemia. | The Journal of laboratory and clinical medicine 20030401 |
| Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. | Archives of neurology 20030401 |
| Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. | Molecular and cellular biochemistry 20030401 |
| Safety and statin therapy: reconsidering the risks and benefits. | Archives of internal medicine 20030324 |
| Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials. | Archives of internal medicine 20030324 |
| Mevastatin can cause G1 arrest and induce apoptosis in pulmonary artery smooth muscle cells through a p27Kip1-independent pathway. | Circulation research 20030321 |
| Comparison of once-daily, niacin extended-release/lovastatin with standard doses of atorvastatin and simvastatin (the ADvicor Versus Other Cholesterol-Modulating Agents Trial Evaluation [ADVOCATE]). | The American journal of cardiology 20030315 |
| Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. | Journal of biotechnology 20030306 |
| Determination of Simvastatin in human plasma by liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305 |
| Three new drugs for hyperlipidemia. | The Medical letter on drugs and therapeutics 20030303 |
| Platelet derived growth factor-BB is a potent mitogen for rat ureteral and human bladder smooth muscle cells: dependence on lipid rafts for cell signaling. | The Journal of urology 20030301 |
| Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress. | Arteriosclerosis, thrombosis, and vascular biology 20030301 |
| Statin effects on cholesterol micro-domains in brain plasma membranes. | Biochemical pharmacology 20030301 |
| Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men. | Medical science monitor : international medical journal of experimental and clinical research 20030301 |
| [Effects of lovastatin on proliferation and gap junctional intercellular communication of human breast cancer cell MCF-7]. | Ai zheng = Aizheng = Chinese journal of cancer 20030301 |
| Treating dyslipidemia with statins: the risk-benefit profile. | American heart journal 20030301 |
| Comparative effects of lovastatin on mammary and prostate oncogenesis in transgenic mouse models. | Carcinogenesis 20030301 |
| A dose-ranging study of a new, once-daily, dual-component drug product containing niacin extended-release and lovastatin. | Clinical cardiology 20030301 |
| [Determination of total lovastatin in red rice]. | Wei sheng yan jiu = Journal of hygiene research 20030301 |
| Regulation of osteoclast differentiation by statins. | Journal of musculoskeletal & neuronal interactions 20030301 |
| Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth. | Biochemical and biophysical research communications 20030227 |
| Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia. | The American journal of cardiology 20030215 |
| Inhibition of cdk2 activating phosphorylation by mevastatin. | The Journal of biological chemistry 20030214 |
| Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression. | Leukemia research 20030201 |
| Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains. | Nature biotechnology 20030201 |
| Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes. | Journal of neurochemistry 20030201 |
| Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. | Biotechnology and applied biochemistry 20030201 |
| Statins can inhibit proliferation of human breast cancer cells in vitro. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201 |
| Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes. | Organic & biomolecular chemistry 20030107 |
| The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content. | Journal of neurochemistry 20030101 |
| Cytochrome P450 drug interactions within the HMG-CoA reductase inhibitor class: are they clinically relevant? | Drug safety 20030101 |
| Niacin-ER and lovastatin treatment of hypercholesterolemia and mixed dyslipidemia. | The Annals of pharmacotherapy 20030101 |
| The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030101 |
| HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20030101 |
| Synergistic activation of human LDL receptor expression by SCAP ligand and cytokine oncostatin M. | Arteriosclerosis, thrombosis, and vascular biology 20030101 |
| Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3. | Journal of leukocyte biology 20030101 |
| Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins. | Leukemia 20030101 |
| Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease. | The European journal of neuroscience 20030101 |
| The statins as anticancer agents. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030101 |
| Comparing HMG-CoA reductase inhibitors. | Clinical cardiology 20030101 |
| Production of the secondary metabolites gamma-aminobutyric acid and monacolin K by Monascus. | Journal of industrial microbiology & biotechnology 20030101 |
| The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer. | Breast cancer research : BCR 20030101 |
| Effects of policosanol and lovastatin in patients with intermittent claudication: a double-blind comparative pilot study. | Angiology 20030101 |
| Cerivastatin: a cellular and molecular drug for the future? | Cellular and molecular life sciences : CMLS 20030101 |
| Production and purification of statins from Pleurotus ostreatus (Basidiomycetes) strains. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101 |
| An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS). | PharmacoEconomics 20030101 |
| Lovastatin extended release: a review of its use in the management of hypercholesterolaemia. | Drugs 20030101 |
| Lopinavir/ritonavir: a review of its use in the management of HIV infection. | Drugs 20030101 |
| The role of intracellular cholesterol on the processing of the beta-amyloid precursor protein. | The journal of nutrition, health & aging 20030101 |
| Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells. | Lipids in health and disease 20030101 |
| Lymphocyte function-associated antigen-1 blockade by statins: molecular basis and biological relevance. | Endothelium : journal of endothelial cell research 20030101 |
| Does simvastatin stimulate bone formation in vivo? | BMC musculoskeletal disorders 20030101 |
| 4-hydroxycinnamate lowers plasma and hepatic lipids without changing antioxidant enzyme activities. | Annals of nutrition & metabolism 20030101 |
| Variable influence of statins on isoprostanes in hyperlipidemia. | Advances in experimental medicine and biology 20030101 |
| Melanoma chemoprevention: a role for statins or fibrates? | American journal of therapeutics 20030101 |
| Characterization of a non-pigment producing Monascus purpureus mutant strain. | Antonie van Leeuwenhoek 20030101 |
| Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs, in HIV-1-infected patients. | BMC infectious diseases 20030101 |
| Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin. | Cell stress & chaperones 20030101 |
| HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages. | Journal of biomedical science 20030101 |
| Potential nontraditional applications of statins. | The Annals of pharmacotherapy 20030101 |
| Comparison of the cholesterol-lowering effects and toxicity of D-003 and lovastatin in normocholesterolaemic rabbits. | Drugs in R&D 20030101 |
| Microencapsulation of lipid nanoparticles containing lipophilic drug. | Journal of microencapsulation 20030101 |
| Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells. | Menopause (New York, N.Y.) 20030101 |
| HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection. | BMC cardiovascular disorders 20030101 |
| HIV protease inhibitors and dyslipidemia. | AIDS reviews 20030101 |
| Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities, and pharmacological functions. | Chemical record (New York, N.Y.) 20030101 |
| Cholesterol-lowering action of policosanol compares well to that of pravastatin and lovastatin. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101 |
| A review of anabolic therapies for osteoporosis. | Arthritis research & therapy 20030101 |
| Clinical pharmacokinetics of statins. | Methods and findings in experimental and clinical pharmacology 20030101 |
| Behavioral implications of lowering cholesterol levels: a double-blind pilot study. | Psychosomatics 20030101 |
| Novel small molecule cyclin-dependent kinases modulators in human clinical trials. | Cancer biology & therapy 20030101 |
| Molecular regulation of cholesterol biosynthesis: implications in carcinogenesis. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101 |
| Pharmacological comparison of the statins. | Arzneimittel-Forschung 20030101 |
| Cinnamate supplementation enhances hepatic lipid metabolism and antioxidant defense systems in high cholesterol-fed rats. | Journal of medicinal food 20030101 |
| Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor. | Clinical & experimental metastasis 20030101 |
| Once-daily niacin extended release/lovastatin combination tablet has more favorable effects on lipoprotein particle size and subclass distribution than atorvastatin and simvastatin. | Preventive cardiology 20030101 |
| Weight uniformity of split tablets required by a Veterans Affairs policy. | Journal of managed care pharmacy : JMCP 20030101 |
| The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903]. | BMC clinical pharmacology 20030101 |
| Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor. | Cardiovascular drug reviews 20030101 |
| Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101 |
| Hypergravity-induced changes in gene expression in Arabidopsis hypocotyls. | Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101 |
| Cholesterol regulates ABCD2 gene expression: implications for X-linked adrenoleukodstrophy. | Advances in experimental medicine and biology 20030101 |
| [Screening of natural immunosuppressors by their ability to modify steroid synthesis in hepatocytes]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101 |
| Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers:gut hydrolysis of lovastatin is twice that of simvastatin. | TheScientificWorldJournal 20030101 |
| Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. | BMC family practice 20030101 |
| [Flotation mass-spectra and surface potential of low density lipoprotein particles of hyperlipidemic patients after forced abolishment of lavostatin treatment]. | Biomeditsinskaia khimiia 20030101 |
| Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells. | Experimental & molecular medicine 20021231 |
| Receptor-dependent regulation of the CYP3A4 gene. | Toxicology 20021227 |
| Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. | Brain research 20021220 |
| 2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery. | Journal of medicinal chemistry 20021219 |
| Chelation-controlled reduction: stereoselective formation of syn-1,3-diols and synthesis of compactin and mevinolin lactone. | The Journal of organic chemistry 20021213 |
| Production of lovastatin examined by an integrated approach based on chemometrics and DOSY-NMR. | Biotechnology and bioengineering 20021205 |
| Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20021201 |
| Monocarboxylate transporter mediates uptake of lovastatin acid in rat cultured mesangial cells. | Journal of pharmaceutical sciences 20021201 |
| Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. | Planta 20021201 |
| X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha. | Structure (London, England : 1993) 20021201 |
| Niacin extended-release/lovastatin: combination therapy for lipid disorders. | Expert opinion on pharmacotherapy 20021201 |
| Origin of the epidermal calcium gradient: regulation by barrier status and role of active vs passive mechanisms. | The Journal of investigative dermatology 20021201 |
| Cerivastatin, a HMG-CoA reductase inhibitor, reduces plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells by down-regulation of cellular signaling and the inhibition of PAI-1 promoter activity. | Japanese journal of pharmacology 20021201 |
| Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. | Plant & cell physiology 20021201 |
| An examination of the effect of cytochrome P450 drug interactions of hydroxymethylglutaryl-coenzyme A reductase inhibitors on health care utilization: a Canadian population-based study. | Clinical therapeutics 20021201 |
| Enzyme inhibitors to increase poly-3-hydroxybutyrate production by transgenic tobacco. | Bioscience, biotechnology, and biochemistry 20021201 |
| Toward a role for statins in immunomodulation. | Molecular interventions 20021201 |
| [Treatment with statins: further data from the Heart Protection Study]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20021130 |
| Side effects of statins--prevalence, relevance, consequences. | Wiener klinische Wochenschrift 20021130 |
| Statin-induced myositis migrans. | Wiener klinische Wochenschrift 20021130 |
| Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin. | Neuroscience letters 20021129 |
| Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis. | The Journal of biological chemistry 20021122 |
| Combination therapy for combined dyslipidemia. | The American journal of cardiology 20021120 |
| Isoprenoids influence expression of Ras and Ras-related proteins. | Biochemistry 20021119 |
| The effects of lovastatin and simvastatin on the diurnal periodicity of plasma mevalonate concentrations in patients with heterozygous familial hypercholesterolemia. | Atherosclerosis 20021101 |
| Early statin therapy for acute coronary syndromes. | The Annals of pharmacotherapy 20021101 |
| In response to Furst et al, 'Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin'. | Biological psychiatry 20021101 |
| Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101 |
| Simvastatin improves fracture healing in mice. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101 |
| Lipid-lowering therapy after coronary artery bypass grafting: time for more aggressive intervention. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101 |
| Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum. | Molecular genetics and genomics : MGG 20021101 |
| Lovastatin does not accentuate but is rather additive to palmitate-induced apoptosis in cardiomyocytes. | Prostaglandins, leukotrienes, and essential fatty acids 20021101 |
| Geranylgeranyl pyrophosphate counteracts the cataractogenic effect of lovastatin on cultured rat lenses. | Experimental eye research 20021101 |
| Preclinical pharmacokinetics of statins. | Methods and findings in experimental and clinical pharmacology 20021101 |
| Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipient. | Transplantation 20021027 |
| Mutant K-ras oncogene regulates steroidogenesis of normal human adrenocortical cells by the RAF-MEK-MAPK pathway. | British journal of cancer 20021021 |
| Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy. | Human molecular genetics 20021015 |
| Statins as immunomodulators: comparison with interferon-beta 1b in MS. | Neurology 20021008 |
| Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients. | Atherosclerosis 20021001 |
| Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation. | The Journal of pharmacology and experimental therapeutics 20021001 |
| A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system. | The Journal of pharmacology and experimental therapeutics 20021001 |
| The HMG-CoA reductase inhibitor lovastatin protects cells from the antineoplastic drugs doxorubicin and etoposide. | International journal of molecular medicine 20021001 |
| Rhabdomyolysis with concurrent atorvastatin and diltiazem. | The Annals of pharmacotherapy 20021001 |
| Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes. | Journal of cardiovascular pharmacology 20021001 |
| Statin-associated myopathy with normal creatine kinase levels. | Annals of internal medicine 20021001 |
| Summaries for patients. Muscle abnormalities in four patients taking statins to treat unfavorable cholesterol levels. | Annals of internal medicine 20021001 |
| On-line analysis of the (13)CO(2) labeling of leaf isoprene suggests multiple subcellular origins of isoprene precursors. | Planta 20021001 |
| Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug. | The American journal of cardiology 20021001 |
| The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. | Endocrine reviews 20021001 |
| Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001 |
| Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. | Arthritis and rheumatism 20021001 |
| [Effect of lovastatin on proliferation and extracellular matrix secretion of rat hepatic stellate cells in vitro]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20021001 |
| Lovastatin alters biliary lipid composition and dissolves gallstones: a long-term study in prairie dogs. | Digestive diseases and sciences 20021001 |
| Lovastatin-stimulated superinduction of E-selectin, ICAM-1 and VCAM-1 in TNF-alpha activated human vascular endothelial cells. | Atherosclerosis 20020901 |
| Influence of atorvastatin and simvastatin on apolipoprotein B metabolism in moderate combined hyperlipidemic subjects with low VLDL and LDL fractional clearance rates. | Atherosclerosis 20020901 |
| Clinical implications of statin event trials. | Current atherosclerosis reports 20020901 |
| Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20020901 |
| Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway. | Cell death and differentiation 20020901 |
| The effects of lovastatin on proteasome activities in highly purified rabbit 20 S proteasome preparations and mouse MC3T3-E1 osteoblastic cells. | Metabolism: clinical and experimental 20020901 |
| Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen. | Medical hypotheses 20020901 |
| Update on the management of dyslipidemia. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020901 |
| Niacin-based therapy for dyslipidemia: past evidence and future advances. | The American journal of managed care 20020901 |
| Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum. | Molecular genetics and genomics : MGG 20020901 |
| Management of dyslipidemia in the primary prevention of coronary heart disease. | Current opinion in cardiology 20020901 |
| Cholesterol attenuates the membrane perturbing properties of beta-amyloid peptides. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20020901 |
| Diabetes and the role of isoprenoid biosynthesis. | FEBS letters 20020814 |
| Lovastatin downregulates renal myofibroblast function in vitro. | Nephron 20020801 |
| Reduction of bFGF-induced smooth muscle cell proliferation and endothelin receptor mRNA expression by mevastatin and atorvastatin. | Biochemical pharmacology 20020801 |
| Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin. | Journal of clinical pharmacology 20020801 |
| HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells. | Clinical science (London, England : 1979) 20020801 |
| Cholesterol and Alzheimer's disease. | Biochemical Society transactions 20020801 |
| Proteome analysis of Aspergillus nidulans reveals proteins associated with the response to the antibiotic concanamycin A, produced by Streptomyces species. | Molecular genetics and genomics : MGG 20020801 |
| Determination of lovastatin and simvastatin in pharmaceutical dosage forms by MEKC. | Journal of pharmaceutical and biomedical analysis 20020720 |
| Targeting the cell cycle for cancer therapy. | British journal of cancer 20020715 |
| Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. | Atherosclerosis 20020701 |
| Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. | Neoplasia (New York, N.Y.) 20020701 |
| Long-term prevention of premature coronary atherosclerosis in homozygous familial hypercholesterolemia. | The Journal of pediatrics 20020701 |
| The cholesterol lowering drug lovastatin induces cell death in myeloma plasma cells. | Leukemia 20020701 |
| Alterations in membrane-bound and cytoplasmic K-ras protein levels in mouse lung induced by treatment with lovastatin, cholestyramine, or niacin: effects are highly mouse strain dependent. | Biochemical pharmacology 20020701 |
| Lovastatin potentiates antitumor activity of doxorubicin in murine melanoma via an apoptosis-dependent mechanism. | International journal of cancer 20020701 |
| Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum. | Molecular genetics and genomics : MGG 20020701 |
| Lovastatin increases longitudinal bone growth and bone morphogenetic protein-2 levels in the growth plate of Sprague-Dawley rats. | European journal of pediatrics 20020701 |
| Inhibition of Rho-kinase induces alphaB-crystallin expression in lens epithelial cells. | Biochemical and biophysical research communications 20020628 |
| The liver and lovastatin. | The American journal of cardiology 20020615 |
| By the way, doctor. I read that they're now selling a cheaper version of Mevacor. But I've also heard that Mevacor isn't as effective as the other statins. What do you think? | Harvard health letter 20020601 |
| Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects. | Journal of neuroscience research 20020601 |
| A clinical and experimental study on the protective effects of jiangzhi tongmai fang on endothelial injury. | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20020601 |
| Policosanol: a new treatment for cardiovascular disease? | Alternative medicine review : a journal of clinical therapeutic 20020601 |
| P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype. | Leukemia & lymphoma 20020601 |
| A randomized, double-blind comparison of cerivastatin and lovastatin for treatment of primary hypercholesterolemia. | Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20020601 |
| Lovastatin induces cell death in cardiomyocytes that is not reversible by coenzyme Q 10. | Pharmacology & toxicology 20020601 |
| Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia. | The American journal of cardiology 20020515 |
| Statins and risk of polyneuropathy: a case-control study. | Neurology 20020514 |
| Low- and high-density lipoprotein cholesterol and ischemic cerebrovascular disease: the bezafibrate infarction prevention registry. | Archives of internal medicine 20020513 |
| Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status. | The Journal of biological chemistry 20020510 |
| Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells. | The Journal of biological chemistry 20020503 |
| Rhabdomyolysis after concomitant use of cyclosporine, simvastatin, gemfibrozil, and itraconazole. | The Annals of pharmacotherapy 20020501 |
| Pharmacokinetics of lovastatin extended-release dosage form (Lovastatin XL) in healthy volunteers. | Biopharmaceutics & drug disposition 20020501 |
| Immunosuppressive effects of statins. | Atherosclerosis. Supplements 20020501 |
| Pharmacological interactions of statins. | Atherosclerosis. Supplements 20020501 |
| Diabetic dyslipidemia. | Atherosclerosis. Supplements 20020501 |
| The choice of hormone replacement therapy or statin therapy in the treatment of hyperlipidemic postmenopausal women. | Atherosclerosis. Supplements 20020501 |
| Quercetin dihydrate and gallate supplements lower plasma and hepatic lipids and change activities of hepatic antioxidant enzymes in high cholesterol-fed rats. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020501 |
| Expression of Nedd5, a mammalian septin, in human brain tumors. | Journal of neuro-oncology 20020501 |
| Plasma homocysteine concentration, statin therapy, and the risk of first acute coronary events. | Circulation 20020416 |
| From the Food and Drug Administration. | JAMA 20020403 |
| Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae. | Atherosclerosis 20020401 |
| Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens. | International journal of oncology 20020401 |
| CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase. | Blood 20020401 |
| Pharmacological concentrations of the HMG-CoA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta-amyloid peptide in vitro and in patients. | Frontiers in bioscience : a journal and virtual library 20020401 |
| Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach. | Archives of insect biochemistry and physiology 20020401 |
| Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs. | Applied microbiology and biotechnology 20020401 |
| Withdrawal of statins increases event rates in patients with acute coronary syndromes. | Circulation 20020326 |
| Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB. | The Journal of biological chemistry 20020322 |
| Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia. | The American journal of cardiology 20020315 |
| Myopathy and rhabdomyolysis with lipid-lowering drugs. | Toxicology letters 20020310 |
| Lovastatin enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: implication of rho-family GTPases. | Circulation research 20020308 |
| Managing dyslipidemia in the high-risk patient. | The American journal of cardiology 20020307 |
| Analytical method for monitoring concentrations of cyclosporin and lovastatin in vitro in an everted rat intestinal sac absorption model. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020305 |
| A novel concept to preserve the beneficial effects of hormone replacement therapy in bilaterally female ovariectomized rats: role of lovastatin therapy. | Pharmacological research 20020301 |
| 3-Morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: a critical role for p21(ras)-MAPK-p19(ARF) pathway. | Nitric oxide : biology and chemistry 20020301 |
| Effect of colesevelam on lovastatin pharmacokinetics. | The Annals of pharmacotherapy 20020301 |
| Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells. | Carcinogenesis 20020301 |
| Simvastatin and lovastatin, but not pravastatin, interact with MDR1. | The Journal of pharmacy and pharmacology 20020301 |
| Assessment of ADRs associated with lipid-lowering agents recorded in the Department of Internal Medicine, University Hospital, Jena. | International journal of clinical pharmacology and therapeutics 20020301 |
| C-reactive protein: from acute phase reactant to cardiovascular disease risk factor. | MLO: medical laboratory observer 20020301 |
| [Stimulation of bone formation by anti-hyperlipidemic agent statins and its mechanism of action]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells. | Cardiovascular drugs and therapy 20020301 |
| Antioxidant treatment of therapy-resistant idiopathic membranous nephropathy with probucol: a pilot study. | Wiener klinische Wochenschrift 20020227 |
| Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. | International journal of cancer 20020220 |
| Goals of statin conversion program. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020215 |
| Therapy and clinical trials. | Current opinion in lipidology 20020201 |
| Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020201 |
| Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans. | Journal of clinical pharmacology 20020201 |
| 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. | Gastroenterology 20020201 |
| Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin. | Biological psychiatry 20020201 |
| Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest. | Leukemia 20020201 |
| FDA adverse event reports on statin-associated rhabdomyolysis. | The Annals of pharmacotherapy 20020201 |
| The subcellular localization of an unusual rice calmodulin isoform, OsCaM61, depends on its prenylation status. | Plant molecular biology 20020201 |
| Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells. | Lipids 20020201 |
| Lipid-lowering long-term effects of six different statins in hypercholesterolemic renal transplant patients under cyclosporine immunosuppression. | Transplantation proceedings 20020201 |
| Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue. | Breast cancer research and treatment 20020201 |
| [Inhibitory effects of lovastatin on the proliferation and cell cycle phase of cultured human glomerular mesangial cells in vitro]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20020201 |
| Dose response, safety, and efficacy of an extended-release formulation of lovastatin in adults with hypercholesterolemia. | The American journal of cardiology 20020115 |
| A general assessment of the safety of HMG CoA reductase inhibitors (statins). | Current atherosclerosis reports 20020101 |
| Cyclin b1 promoter activity and functional cdk1 complex formation in G1 phase of human breast cancer cells. | Cell biology international 20020101 |
| HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins. | British journal of pharmacology 20020101 |
| Cholesterol, essential fatty acids, and suicide. | Pharmacopsychiatry 20020101 |
| A multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin. | Clinical therapeutics 20020101 |
| Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. | Cellular microbiology 20020101 |
| Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers. | European journal of clinical pharmacology 20020101 |
| [Schistosoma mansoni: the action of lovastatin on the murine model]. | Revista da Sociedade Brasileira de Medicina Tropical 20020101 |
| Effect of simvastatin on bone markers in osteopenic women: a placebo-controlled, dose-ranging trial [ISRCTN85429598]. | BMC musculoskeletal disorders 20020101 |
| Morphologic change and elevation of cortisol secretion in cultured human normal adrenocortical cells caused by mutant p21K-ras protein. | DNA and cell biology 20020101 |
| Advicor (niacin extended-release and lovastatin tablets). | Journal of clinical hypertension (Greenwich, Conn.) 20020101 |
| The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution. | BMC pharmacology 20020101 |
| Lovastatin and extended-release niacin combination product: the first drug combination for the management of hyperlipidemia. | Heart disease (Hagerstown, Md.) 20020101 |
| Lovastatin is a potent inhibitor of meningioma cell proliferation: evidence for inhibition of a mitogen associated protein kinase. | Journal of neuro-oncology 20020101 |
| Statins as modulators of bone formation. | Arthritis research 20020101 |
| Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. | Clinical pharmacokinetics 20020101 |
| Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway. | Oncology reports 20020101 |
| Synergistic interaction between highly specific cyclooxygenase-2 inhibitor, MF-tricyclic and lovastatin in murine colorectal cancer cell lines. | Oncology reports 20020101 |
| Food-drug interactions. | Drugs 20020101 |
| The role of statins as potential targets for bone formation. | Arthritis research 20020101 |
| Insights into integrin-ligand binding and activation from the first crystal structure. | Arthritis research 20020101 |
| [Myopathy due to statins, a dose-dependent effect, and of what kind?]. | Atencion primaria 20020101 |
| Reappraisal of G1-phase arrest and synchronization by lovastatin. | Cell biology international 20020101 |
| Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy. | Drug safety 20020101 |
| [Concentration on Diapak C 16 capsules of lovastatin, mevinolinic acid and other inhibitors of biosynthesis of sterins produced by Penicillium citrinum 89]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101 |
| Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells. | Physiological chemistry and physics and medical NMR 20020101 |
| Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells. | Clinical & experimental metastasis 20020101 |
| Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection. | Clinical pharmacokinetics 20020101 |
| Benefits and menaces related to the use of statins in patients after renal transplantation. | Annals of transplantation 20020101 |
| Statins and menopause. | Drugs 20020101 |
| Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL. | Cell cycle (Georgetown, Tex.) 20020101 |
| A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients. | BMC nephrology 20020101 |
| The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells. | BMC complementary and alternative medicine 20020101 |
| The discovery and development of atorvastatin, a potent novel hypolipidemic agent. | Progress in medicinal chemistry 20020101 |
| Effects of nicotinic acid and lovastatin in combination with cholestyramine in renal transplant patients. | Missouri medicine 20020101 |
| Effect of rice--glycerol complex medium on the production of Lovastatin by Monascus ruber. | Folia microbiologica 20020101 |
| Effects of policosanol and lovastatin on lipid profile and lipid peroxidation in patients with dyslipidemia associated with type 2 diabetes mellitus. | International journal of clinical pharmacology research 20020101 |
| The eye lens evaluation of the atorvastatin-treated white rat. | Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101 |
| Effects of a tablet-splitting program in patients taking HMG-CoA reductase inhibitors: analysis of clinical effects, patient satisfaction, compliance, and cost avoidance. | Journal of managed care pharmacy : JMCP 20020101 |
| Management of protease inhibitor-associated hyperlipidemia. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
| Application of oxygen vectors to Aspergillus terreus cultivation. | Journal of bioscience and bioengineering 20020101 |
| Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins. | The Journal of biological chemistry 20011214 |
| Phosphatidylinositol 3-kinase and Ras/mitogen-activated protein kinase signaling pathways are required for the regulation of 5-aminolevulinate synthase gene expression by insulin. | Experimental cell research 20011210 |
| Diels-Alderases. | Chembiochem : a European journal of chemical biology 20011203 |
| Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolemic rabbits. | Journal of cardiovascular pharmacology 20011201 |
| Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells. | The Biochemical journal 20011201 |
| Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats. | Clinica chimica acta; international journal of clinical chemistry 20011201 |
| Are there potential non-lipid-lowering uses of statins in the kidney? | Nephron 20011201 |
| Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells. | Biochemical pharmacology 20011201 |
| Alpha tocopheryl succinate, retinoic acid and polar carotenoids enhanced the growth-inhibitory effect of a cholesterol-lowering drug on immortalized and transformed nerve cells in culture. | Journal of the American College of Nutrition 20011201 |
| Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): efficacy and tolerability of long-term treatment with lovastatin in women. | Journal of women's health & gender-based medicine 20011201 |
| Comparison of endothelial pleiotropic actions of angiotensin converting enzyme inhibitors and statins. | Annals of the New York Academy of Sciences 20011201 |
| Synergistic interaction of lovastatin and paclitaxel in human cancer cells. | Molecular cancer therapeutics 20011201 |
| [Effects of lovastatin combined with cyclosporine A on cultured human peripheral blood mononuclear cells proliferation, cytokines expression and cytotoxicity]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20011201 |
| Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi. | European journal of pharmacology 20011130 |
| Effect of an aggressive lipid-lowering strategy on progression of atherosclerosis in the left main coronary artery from patients in the post coronary artery bypass graft trial. | Circulation 20011127 |
| Regulation of hepatic lanosterol 14 alpha-demethylase gene expression by dietary cholesterol and cholesterol-lowering agents. | Archives of biochemistry and biophysics 20011115 |
| Comparative squalene synthase gene expression in mouse liver and testis. | Archives of biochemistry and biophysics 20011115 |
| CNS synaptogenesis promoted by glia-derived cholesterol. | Science (New York, N.Y.) 20011109 |
| Locking a leukocyte integrin with statins. | The New England journal of medicine 20011108 |
| Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3-L1 adipocytes. | FEBS letters 20011102 |
| Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits. | Life sciences 20011102 |
| Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B. | European journal of endocrinology 20011101 |
| Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells. | Chinese medical journal 20011101 |
| Inflammatory mechanisms in atherosclerosis: from laboratory evidence to clinical application. | Italian heart journal : official journal of the Italian Federation of Cardiology 20011101 |
| [In vitro effect of lovastatin on NB4 promyelocytic leukemia cells]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20011101 |
| Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis. | Circulation 20011030 |
| The antiinflammatory effects of statins. | The New England journal of medicine 20011018 |
| The antiinflammatory effects of statins. | The New England journal of medicine 20011018 |
| [Can the action of statins reveal etiology of coronary diseases?]. | Lakartidningen 20011017 |
| Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. | Journal of neuroscience research 20011015 |
| beta-Oxidation of simvastatin in mouse liver preparations. | Drug metabolism and disposition: the biological fate of chemicals 20011001 |
| Hyperlipidaemia and cardiovascular disease. | Current opinion in lipidology 20011001 |
| Lovastatin-induced E2F-1 modulation and its effect on prostate cancer cell death. | Carcinogenesis 20011001 |
| Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases. | Investigative ophthalmology & visual science 20011001 |
| The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs. | Metabolism: clinical and experimental 20011001 |
| Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells. | Journal of lipid research 20011001 |
| Effects of prolonged intensive lipid-lowering therapy on the characteristics of carotid atherosclerotic plaques in vivo by MRI: a case-control study. | Arteriosclerosis, thrombosis, and vascular biology 20011001 |
| Biosynthetic pathway of insect juvenile hormone III in cell suspension cultures of the sedge Cyperus iria. | Plant physiology 20011001 |
| [Cholesterol, omega-3 fatty acids, and suicide risk: empirical evidence and pathophysiological hypotheses]. | Fortschritte der Neurologie-Psychiatrie 20011001 |
| Managed care trends in statin usage. | Managed care (Langhorne, Pa.) 20011001 |
| Statins in children. Why and when. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20011001 |
| Safety and efficacy of treatment of children and adolescents with elevated low density lipoprotein levels with a step two diet or with lovastatin. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20011001 |
| Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner. | Atherosclerosis 20010901 |
| CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts. | American journal of physiology. Cell physiology 20010901 |
| Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer. | Mutation research 20010901 |
| Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells. | Leukemia 20010901 |
| Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis. | Tennessee medicine : journal of the Tennessee Medical Association 20010901 |
| Effects of lovastatin and pravastatin on cognitive function in military aircrew. | Aviation, space, and environmental medicine 20010901 |
| Smoking diminishes the beneficial effect of statins: observations from the landmark trials. | Angiology 20010901 |
| C-reactive protein, coronary risk, and statins. | Harvard women's health watch 20010901 |
| Oxidation of lovastatin in the solid state and its stabilization with natural antioxidants. | Die Pharmazie 20010901 |
| Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner. | Methods and findings in experimental and clinical pharmacology 20010901 |
| Statins in the 21st century: end of the simple story? | Expert opinion on investigational drugs 20010901 |
| In vitro antitumor activity of cerivastatin, a novel and potent HMG-CoA reductase inhibitor. | FEBS letters 20010817 |
| Efficient antitumor immunity derived from maturation of dendritic cells that had phagocytosed apoptotic/necrotic tumor cells. | International journal of cancer 20010815 |
| Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins. | The American journal of medicine 20010815 |
| Interaction of cytosine arabinoside and lovastatin in human leukemia cells. | Leukemia research 20010801 |
| The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'. | Leukemia research 20010801 |
| Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca(2+) mobilization, and apoptosis. | Journal of neurobiology 20010801 |
| Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. | Experimental eye research 20010801 |
| Correlation of non-high-density lipoprotein cholesterol with apolipoprotein B: effect of 5 hydroxymethylglutaryl coenzyme A reductase inhibitors on non-high-density lipoprotein cholesterol levels. | The American journal of cardiology 20010801 |
| Action of an HMG CoA reductase inhibitor, lovastatin, on apoptosis of untransformed and ts-SV40 transformed human smooth muscle cells derived from saphenous vein. | Journal of cardiovascular pharmacology 20010801 |
| Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins). | British journal of pharmacology 20010801 |
| Possible relationship between statin use and decreased incidence of dementia: are we ready for a new indication for these drugs? | Archives of internal medicine 20010801 |
| Pleiotropic effects of statins: do they matter? | Current opinion in lipidology 20010801 |
| By the way, doctor... My brother takes Mevacor and has been told to take the drug at bedtime. But when I started on Lipitor, my doctor said to take the medication at any time of the day. Why the difference? | Harvard health letter 20010801 |
| Polyketide biosynthesis: a millennium review. | Natural product reports 20010801 |
| Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). | European journal of clinical pharmacology 20010801 |
| Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J. | Biochemical and biophysical research communications 20010720 |
| Coronary artery disease progression assessed by electron-beam computed tomography. | The American journal of cardiology 20010719 |
| HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. | Carcinogenesis 20010701 |
| Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes. | Journal of cardiovascular pharmacology 20010701 |
| Statins and dementia. | Archives of neurology 20010701 |
| Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010701 |
| Essential fatty acids as possible mediators of the actions of statins. | Prostaglandins, leukotrienes, and essential fatty acids 20010701 |
| Statin therapy and stroke prevention. | Current opinion in cardiology 20010701 |
| The role of cytochrome P450-mediated drug-drug interactions in determining the safety of statins. | Expert opinion on pharmacotherapy 20010701 |
| Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions. | Journal of cardiovascular pharmacology and therapeutics 20010701 |
| Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives. | Biochimica et biophysica acta 20010629 |
| Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. | The New England journal of medicine 20010628 |
| Statins and the acute-phase response. | The New England journal of medicine 20010628 |
| The HDV large-delta antigen fused with GFP remains functional and provides for studying its dynamic distribution. | Virology 20010620 |
| Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus. | Bioorganic & medicinal chemistry letters 20010618 |
| Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. | Cancer research 20010615 |
| Use of statins and the subsequent development of deep vein thrombosis. | Archives of internal medicine 20010611 |
| Compactin enhances osteogenesis in murine embryonic stem cells. | Biochemical and biophysical research communications 20010608 |
| Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. | Nature medicine 20010601 |
| Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection. | Clinical transplantation 20010601 |
| Low-dose combination therapy with colesevelam hydrochloride and lovastatin effectively decreases low-density lipoprotein cholesterol in patients with primary hypercholesterolemia. | Clinical cardiology 20010601 |
| Statin therapy and the prevention of dementia. | Archives of neurology 20010601 |
| [Improvement of endothelial function in patients with hypercholesterolemia and normal coronary arteries with lipid-lowering therapy]. | Revista espanola de cardiologia 20010601 |
| Inhibition of growth of methane-producing bacteria of the ruminant forestomach by hydroxymethylglutaryl-SCoA reductase inhibitors. | Journal of dairy science 20010601 |
| Plasmodium falciparum: the lethal effects of tunicamycin and mevastatin on the parasite are not mediated by the inhibition of N-linked oligosaccharide biosynthesis. | Experimental parasitology 20010601 |
| Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide. | The international journal of neuropsychopharmacology 20010601 |
| HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. | Pharmaceutical research 20010601 |
| Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. | Journal of chromatography. A 20010525 |
| Regulation of sterol regulatory element-binding proteins in hamster intestine by changes in cholesterol flux. | The Journal of biological chemistry 20010518 |
| RhoA is activated during respiratory syncytial virus infection. | Virology 20010510 |
| Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury. | Kidney international 20010501 |
| Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins? | Trends in molecular medicine 20010501 |
| Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatin. | The American journal of cardiology 20010501 |
| The combined effects of novel tocotrienols and lovastatin on lipid metabolism in chickens. | Atherosclerosis 20010501 |
| Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate. | Clinical pharmacology and therapeutics 20010501 |
| Long-term administration of the HMG-CoA reductase inhibitor lovastatin in two patients with cholesteryl ester storage disease. | International journal of clinical pharmacology and therapeutics 20010501 |
| Should all patients with cardiovascular disease receive statin therapy? | The American journal of managed care 20010501 |
| Statins--similarities and differences. | The American journal of managed care 20010501 |
| What do the statin trials tell us? | The American journal of managed care 20010501 |
| Revised indications for statin therapies. | Angiology 20010501 |
| Statin induced myopathy does not show up in MIBI scintigraphy. | Nuclear medicine communications 20010501 |
| The National Service Framework on coronary heart disease: is it sufficiently evidence-based? | Annals of clinical biochemistry 20010501 |
| Statins and bone formation. | Current pharmaceutical design 20010501 |
| Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents. | Lipids 20010501 |
| [Effect of monascus on improving the hemorheology of rats with high blood lipids]. | Wei sheng yan jiu = Journal of hygiene research 20010501 |
| Methods for synchronizing cells at specific stages of the cell cycle. | Current protocols in cell biology 20010501 |
| Deterioration of the protein kinase C-K(ATP) channel pathway in regulation of coronary flow in hypercholesterolaemic rabbits. | European journal of pharmacology 20010427 |
| Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry. | Journal of chromatography. B, Biomedical sciences and applications 20010425 |
| Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice. | Neuroreport 20010417 |
| Assessing the results: phase 1 hyperlipidemia outcomes in 27 health plans. | The American journal of medicine 20010416 |
| Statins are magic when you gotta have heart. | U.S. news & world report 20010416 |
| The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana. | The Journal of biological chemistry 20010413 |
| Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts. | Journal of cellular physiology 20010401 |
| Comparative study of HMG-CoA reductase inhibitors on fibrinogen. | Atherosclerosis 20010401 |
| Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro. | Antimicrobial agents and chemotherapy 20010401 |
| Rho GTPases are involved in the regulation of NF-kappaB by genotoxic stress. | Experimental cell research 20010401 |
| A new simvastatin (mevinolin)-resistance marker from Haloarcula hispanica and a new Haloferax volcanii strain cured of plasmid pHV2. | Microbiology (Reading, England) 20010401 |
| Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice. | Stroke 20010401 |
| The effects of the statins lovastatin and cerivastatin on signalling by the prostanoid IP-receptor. | British journal of pharmacology 20010401 |
| An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents. | Journal of alternative and complementary medicine (New York, N.Y.) 20010401 |
| 3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene. | Insect biochemistry and molecular biology 20010315 |
| High apolipoprotein B with low high-density lipoprotein cholesterol and normal plasma triglycerides and cholesterol. | The American journal of cardiology 20010315 |
| A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro. | Drug metabolism and disposition: the biological fate of chemicals 20010301 |
| HMG-CoA reductase inhibitors and P-glycoprotein modulation. | British journal of pharmacology 20010301 |
| Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228. | International journal of cancer 20010301 |
| Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells. | Acta neuropathologica 20010301 |
| Is a statin a statin? | International journal of clinical practice 20010301 |
| [Effect of cholesterol deficiency on the membrane fluidity of Jurkat T lymphocytes]. | Wei sheng yan jiu = Journal of hygiene research 20010301 |
| Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition. | European journal of cell biology 20010301 |
| [AFCAPS/TexCAPS [The Air Force/Texas Coronary Atherosclerosis Prevention Study]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [Statins do not prevent restenosis after coronary angioplasty: where to go from here?]. | Herz 20010301 |
| Recent advances in the biosynthetic studies of lovastatin. | Current opinion in drug discovery & development 20010301 |
| Role of inhibitors of isoprenylation in proliferation, phenotype and apoptosis of human retinal pigment epithelium. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010301 |
| A clinical focus on statins. | Current opinion in investigational drugs (London, England : 2000) 20010301 |
| [HMG-CoA reductase inhibitors and sexual dysfunction]. | Anales de medicina interna (Madrid, Spain : 1984) 20010301 |
| Butyrate-induced differentiation of Caco-2 cells occurs independently from p27. | Biochemical and biophysical research communications 20010223 |
| Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment. | Circulation 20010213 |
| Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation. | Molecular pharmacology 20010201 |
| Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease. | Cardiovascular research 20010201 |
| Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions. | The Biochemical journal 20010201 |
| Bimonthly update. Therapy and clinical trials. | Current opinion in lipidology 20010201 |
| Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. | Molecular and cellular neurosciences 20010201 |
| Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin. | Journal of lipid research 20010201 |
| Do HMG-CoA reductase inhibitors affect fibrinogen? | The Annals of pharmacotherapy 20010201 |
| [Statins: a major therapeutic breakthrough]. | Annales d'endocrinologie 20010201 |
| [Mechanisms of action of statins and their pleiotropic effects]. | Annales d'endocrinologie 20010201 |
| [Statins and stroke]. | Annales d'endocrinologie 20010201 |
| [Kidney and statins]. | Annales d'endocrinologie 20010201 |
| [Statins and diabetic hyperlipidemia]. | Annales d'endocrinologie 20010201 |
| [Statins: intervention studies, facts and perspectives]. | Annales d'endocrinologie 20010201 |
| [Practical questions for the expert]. | Annales d'endocrinologie 20010201 |
| [Endocrine disease in adrenoleukodystrophy]. | Annales de medecine interne 20010201 |
| Lovastatin induced control of blast cell growth in an elderly patient with acute myeloblastic leukemia. | Leukemia & lymphoma 20010201 |
| Metabolites of Monascus ruber in silages. | Journal of animal physiology and animal nutrition 20010201 |
| [The role of HDL in the prevention of cardiovascular events]. | Orvosi hetilap 20010121 |
| [Metabolic interactions with statins]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120 |
| Heart disease. Rethinking treatments for the heart. | Time 20010115 |
| Effective use of statins to prevent coronary heart disease. | American family physician 20010115 |
| Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha). | Gene 20010110 |
| Apolipoprotein B versus lipoprotein lipids: vital lessons from the AFCAPS/TexCAPS trial. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010109 |
| Statin trials in progress: unanswered questions. | Current atherosclerosis reports 20010101 |
| New statins and new doses of older statins. | Current atherosclerosis reports 20010101 |
| Statins in children: what do we know and what do we need to do? | Current atherosclerosis reports 20010101 |
| The benefits of niacin in atherosclerosis. | Current atherosclerosis reports 20010101 |
| Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study. | Journal of clinical pharmacology 20010101 |
| Molecular effects of HMG-CoA reductase inhibitors on smooth muscle cell proliferation. | Journal of the American College of Cardiology 20010101 |
| Fragmentation study of simvastatin and lovastatin using electrospray ionization tandem mass spectrometry. | Journal of mass spectrometry : JMS 20010101 |
| Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | The Annals of pharmacotherapy 20010101 |
| Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |
| A comparative study of policosanol vs lovastatin on intimal thickening in rabbit cuffed carotid artery. | Pharmacological research 20010101 |
| Cholesterol-dependent modulation of tau phosphorylation in cultured neurons. | Journal of neurochemistry 20010101 |
| The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer. | Breast cancer research : BCR 20010101 |
| Cost effectiveness of HMG-CoA reductase inhibition in Canada. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20010101 |
| Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma. | Investigational new drugs 20010101 |
| New OTC drugs and devices 2000: a selective review. | Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101 |
| Liver regeneration after hepatectomy. | Hepato-gastroenterology 20010101 |
| Lovastatin controls signal transduction in vascular smooth muscle cells by modulating phosphorylation levels of mevalonate-independent pathways. | Basic research in cardiology 20010101 |
| Statin-stimulated nitric oxide release from endothelium. | Medical science monitor : international medical journal of experimental and clinical research 20010101 |
| Statin therapy. | Clinical medicine (London, England) 20010101 |
| Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins. | Journal of cardiovascular pharmacology and therapeutics 20010101 |
| [Therapeutic and pleiotropic effects of statins in primary and secondary prevention of atherosclerosis]. | Bulletin de l'Academie nationale de medecine 20010101 |
| Lipid-lowering medications: what the new guidelines and data mean to women. | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20010101 |
| [Substantiation of increasing doses of statins in clinical practice]. | Terapevticheskii arkhiv 20010101 |
| [Effects of pathogenetic therapy on blood cholesterol in patients with glomerulonephritis]. | Terapevticheskii arkhiv 20010101 |
| Transplanted livers and kidneys for HIV+ people. | TreatmentUpdate 20010101 |
| Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. | Molecular genetics and metabolism 20010101 |
| Melanoma. | The oncologist 20010101 |
| Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia. | Drugs 20010101 |
| Using test dose challenges to restore essential therapy in patients with idiopathic anaphylaxis and pharmacophobia: report of a patient with idiopathic anaphylaxis and statin phobia. | Allergy and asthma proceedings 20010101 |
| Statins as immunomodulatory drugs. | Advances in experimental medicine and biology 20010101 |
| Some nutritional factors influencing mevinolin production by Aspergillus terreus strain. | Folia microbiologica 20010101 |
| If LDL-C is the answer...what was the question? What do the data really show? | Heart disease (Hagerstown, Md.) 20010101 |
| Colesevelam: a new bile acid sequestrant. | Heart disease (Hagerstown, Md.) 20010101 |
| Pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone. | The Journal of eukaryotic microbiology 20010101 |
| Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac. | Cardiovascular toxicology 20010101 |
| Colesevelam. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101 |
| Increased lipid peroxidation in a patient with CK-elevation and muscle pain during statin therapy. | Atherosclerosis 20001101 |
| Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. | The Journal of biological chemistry 20001027 |
| Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of pneumocystis carinii f. sp. carinii. | Antimicrobial agents and chemotherapy 20000601 |
| Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture. | Atherosclerosis 20000601 |
| Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells. | Biochemical and biophysical research communications 20000519 |
| Lovastatin potentiates antitumor activity and attenuates cardiotoxicity of doxorubicin in three tumor models in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20000501 |
| Does vitamin E beneficially affect muscle pains during HMG-Co-enzyme-A-reductase inhibitors without CK-elevation? | Atherosclerosis 20000301 |
| Lovastatin inhibits G1/S transition of normal human B-lymphocytes independent of apoptosis. | Experimental cell research 19991010 |
| Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac. | Gastroenterology 19991001 |
| Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 19990801 |
| Effect of lipid-lowering strategies on tubular cell biology. | Kidney international. Supplement 19990701 |
| Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids. | The Journal of nutrition 19990401 |
| Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment. | Atherosclerosis 19990401 |
| Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases. | Chest 19990301 |
| Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro. | Journal of neuro-oncology 19990301 |
| Statins and peripheral neuropathy. | European journal of clinical pharmacology 19990101 |
| Lovastatin inhibits mesangial cell proliferation via p27Kip1. | Journal of the American Society of Nephrology : JASN 19981201 |
| The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. | Cancer research 19981201 |
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. | The Journal of clinical investigation 19980901 |
| Peripheral neuropathy and lipid-lowering therapy. | Southern medical journal 19980701 |
| Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells. | Journal of cellular physiology 19980501 |
| Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19980401 |
| Aggressive lipid lowering in postcoronary angioplasty patients with elevated cholesterol (the Lovastatin Restenosis Trial). | The American journal of cardiology 19980301 |
| Dose- and time-dependent hypocholesterolemic effect of oyster mushroom (Pleurotus ostreatus) in rats. | Nutrition (Burbank, Los Angeles County, Calif.) 19980301 |
| Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome. | Journal of the American Society of Nephrology : JASN 19980201 |
| Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells. | Biochimica et biophysica acta 19971030 |
| (1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor. | Journal of medicinal chemistry 19970704 |
| Comparison of bezafibrate and simvastatin in the treatment of dyslipidaemia in patients with NIDDM. | Diabetic medicine : a journal of the British Diabetic Association 19970701 |
| Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy. | Japanese heart journal 19970701 |
| Rationale and design features of a clinical trial examining the effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT). SCAT Investigators. | The Canadian journal of cardiology 19970601 |
| [Myopathy caused by inhibitors of hydroxymethylglutaryl-coenzyme A reductase]. | Revista de neurologia 19970601 |
| Polymyositis associated with simvastatin. | Lancet (London, England) 19970531 |
| Rhabdomyolysis associated with simvastatin-gemfibrozil therapy. | Southern medical journal 19970501 |
| Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity. | Oncogene 19970123 |
| Myositis and rhabdomyolysis associated with concurrent use of simvastatin and nefazodone. | JAMA 19970101 |
| A head-to-head comparison of the cost effectiveness of HMG-CoA reductase inhibitors and fibrates in different types of primary hyperlipidemia. | Cardiovascular drugs and therapy 19970101 |
| Simvastatin-induced myopathy in a patient treated for hypercholesterolemia. Morphological aspects. | Polish journal of pathology : official journal of the Polish Society of Pathologists 19970101 |
| Human multidrug-resistant (MRP,p190) myeloid leukemia HL-60/ADR cells in vitro: resistance to the mevalonate pathway inhibitor lovastatin. | Neoplasma 19970101 |
| Acute on chronic renal failure induced by simvastatin. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19961101 |
| Lovastatin-associated dermatomyositis. | Postgraduate medical journal 19961101 |
| [Hepatitis due to lovastatin]. | Medicina clinica 19961026 |
| Myoglobinuric renal failure due to long-standing lovastatin therapy in a patient with pre-existing chronic renal insufficiency. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19961001 |
| Effects of HMG-CoA reductase inhibitors on growth and differentiation of cultured rat skeletal muscle cells. | Biochimica et biophysica acta 19960412 |
| HMG-CoA reductase inhibitor-induced impotence. | The Annals of pharmacotherapy 19960201 |
| Fluvastatin in combination with other lipid-lowering agents. | British journal of clinical practice. Supplement 19960101 |
| [Terminal myoglobinuric renal failure in lovastatin therapy with pre-existing chronic renal insufficiency]. | Wiener klinische Wochenschrift 19960101 |
| Lovastatin and peripheral neuropathy. | American heart journal 19951201 |
| Enalapril and peripheral neuropathy. | Journal of the American Geriatrics Society 19951001 |
| Currently available hypolipidaemic drugs and future therapeutic developments. | Bailliere's clinical endocrinology and metabolism 19951001 |
| Lovastatin-induced myopathy in a hypothyroid patient. | The Journal of family practice 19950901 |
| Lovastatin-induced hemolytic anemia: not a class-specific reaction. | The American journal of medicine 19950901 |
| Depression-induced absenteeism in relation to antihyperlipidemic treatment: a study using GAZEL cohort data. | Epidemiology (Cambridge, Mass.) 19950501 |
| Peripheral neuropathy associated with simvastatin. | Journal of neurology, neurosurgery, and psychiatry 19950501 |
| [Lovastatin-induced acute cholestatic hepatitis]. | Deutsche medizinische Wochenschrift (1946) 19950224 |
| In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. | Cancer research 19950201 |
| Fluvastatin in combination with other lipid-lowering agents. | British journal of clinical practice. Supplement 19941201 |
| Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up. | The American journal of cardiology 19941001 |
| Synthesis and biological activity of bile acid-derived HMG-CoA reductase inhibitors. The role of 21-methyl in recognition of HMG-CoA reductase and the ileal bile acid transport system. | Journal of medicinal chemistry 19940930 |
| Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene. | Japanese journal of cancer research : Gann 19940601 |
| HMG-CoA reductase inhibitor therapy and peripheral neuropathy. | Annals of internal medicine 19940601 |
| Sleep disturbance and appetite loss after lovastatin. | Lancet (London, England) 19940416 |
| Isoprenoid biosynthesis in rat liver mitochondria. Studies on farnesyl pyrophosphate synthase and trans-prenyltransferase. | The Journal of biological chemistry 19940225 |
| Simvastatin-associated dermatomyositis. | British journal of rheumatology 19940201 |
| [Porphyria cutanea tarda induced by HMG CoA reductase inhibitors: simvastatin, pravastatin]. | Annales de dermatologie et de venereologie 19940101 |
| Effect of simvastatin treatment on plasma apolipoproteins and hepatic apolipoprotein mRNA levels in the genetically hypercholesterolemic rat (RICO). | Life sciences 19940101 |
| Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors. | Journal of medicinal chemistry 19931112 |
| Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors. | Journal of medicinal chemistry 19931112 |
| HMG-CoA reductase inhibitors: design, synthesis, and biological activity of tetrahydroindazole-substituted 3,5-dihydroxy-6-heptenoic acid sodium salts. | Journal of medicinal chemistry 19931112 |
| Unrecognized adverse drug reactions. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19931101 |
| Lovastatin-associated sleep and mood disturbances. | The American journal of medicine 19931101 |
| Simvastatin inhibits PDGF-induced DNA synthesis in human glomerular mesangial cells. | Kidney international 19930901 |
| Rhabdomyolysis and renal failure secondary to combination therapy of hyperlipidemia with lovastatin and gemfibozil. | Connecticut medicine 19930901 |
| Experimental lovastatin myopathy. | Journal of neuropathology and experimental neurology 19930901 |
| Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering. | Journal of medicinal chemistry 19930723 |
| [Psychiatric disorders with use of simvastatin]. | Nederlands tijdschrift voor geneeskunde 19930626 |
| Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase. | Biochemical pharmacology 19930609 |
| Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia. | Annals of internal medicine 19930601 |
| Lovastatin 5-year safety and efficacy study. Lovastatin Study Groups I through IV. | Archives of internal medicine 19930510 |
| The effect of the HMG-CoA reductase inhibitor simvastatin and of cholestyramine on hepatic apolipoprotein mRNA levels in the rat. | Biochimica et biophysica acta 19930317 |
| Lovastatin and cholestasis. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19930201 |
| Depressive symptoms and cholesterol-lowering drugs. | Lancet (London, England) 19930109 |
| Influence of specific mutations at the LDL-receptor gene locus on the response to simvastatin therapy in Afrikaner patients with heterozygous familial hypercholesterolaemia. | Atherosclerosis 19930104 |
| Effects of anti-hyperlipidaemic agent or dietary protein restriction on progressive renal deterioration in adriamycin-induced nephropathy in rats. | International urology and nephrology 19930101 |
| RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent. | Pharmacology 19930101 |
| 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs. | Journal of medicinal chemistry 19921016 |
| Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Journal of medicinal chemistry 19920904 |
| [Toxic drug-induced hyposmia with lovastatin]. | Laryngo- rhino- otologie 19920901 |
| Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia. | The Quarterly journal of medicine 19920901 |
| Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes. | Biochimica et biophysica acta 19920709 |
| Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias. | The American journal of cardiology 19920701 |
| Myopathy associated with HMG-CoA reductase inhibitors (HMGRIs) and cyclosporin A: evaluation in a rat model. | European heart journal 19920701 |
| Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones. | Journal of medicinal chemistry 19920529 |
| Lovastatin-induced hepatitis. | Israel journal of medical sciences 19920201 |
| Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19920106 |
| Hepatotoxicity of hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors. | Minerva gastroenterologica e dietologica 19920101 |
| Lovastatin/gemfibrozil myopathy: a clinical, histochemical, and ultrastructural study. | European neurology 19920101 |
| Lack of hypotension with lovastatin and pravastatin. | Lancet (London, England) 19911123 |
| Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids. | Journal of medicinal chemistry 19911001 |
| Gemfibrozil-induced myopathy. | Archives of internal medicine 19910901 |
| Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety. | Journal of medicinal chemistry 19910901 |
| 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 7. Modification of the hexahydronaphthalene moiety of simvastatin: 5-oxygenated and 5-oxa derivatives. | Journal of medicinal chemistry 19910801 |
| Cholesterol-lowering agent myopathy (CLAM). | Neurology 19910701 |
| HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies. | The Journal of pharmacology and experimental therapeutics 19910601 |
| [Cholestatic jaundice during lovastatin medication]. | Deutsche medizinische Wochenschrift (1946) 19910510 |
| Effect of simvastatin (MK-733) on plasma triacylglycerol levels in rats. | Biochemical pharmacology 19910415 |
| Simvastatin and proteinuria. | Lancet (London, England) 19910406 |
| Acute cholestatic hepatitis during simvastatin administration. | Recenti progressi in medicina 19910401 |
| Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. | Archives of internal medicine 19910101 |
| Inhibitors of cholesterol biosynthesis. 4. trans-6-[2-(substituted-quinolinyl)ethenyl/ethyl]tetrahydro-4-hydroxy-2 H-pyran-2-ones, a novel series of HMG-CoA reductase inhibitors. | Journal of medicinal chemistry 19910101 |
| Rhabdomyolysis with simvastatin use. | Nephron 19910101 |
| Proteinuria as complication of simvastatin treatment. | Lancet (London, England) 19901208 |
| Rhabdomyolysis secondary to lovastatin therapy. | Clinical chemistry 19901201 |
| Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. | Journal of medicinal chemistry 19901101 |
| Lovastatin decreases coenzyme Q levels in humans. | Proceedings of the National Academy of Sciences of the United States of America 19901101 |
| Inhibitors of hydroxymethylglutaryl coenzyme A reductase for treating hypercholesterolaemia. | BMJ (Clinical research ed.) 19900929 |
| Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy. | JAMA 19900704 |
| Cholestatic jaundice associated with lovastatin (Mevacor) therapy. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19900415 |
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