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Home > Other Building Blocks > 74764-40-2
74764-40-2 | Bepridil hydrochloride
CAS No: 74764-40-2 Catalog No: AG005HAC MDL No:
Product Description
Catalog Number:
AG005HAC
Chemical Name:
Bepridil hydrochloride
CAS Number:
74764-40-2
Molecular Formula:
C24H35ClN2O
Molecular Weight:
403.0005
IUPAC Name:
N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline;hydrochloride
InChI:
InChI=1S/C24H34N2O.ClH/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22;/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3;1H
InChI Key:
JXBBWYGMTNAYNM-UHFFFAOYSA-N
SMILES:
CC(COCC(N1CCCC1)CN(c1ccccc1)Cc1ccccc1)C.Cl
EC Number:
268-472-2
NSC Number:
758390
Properties
Complexity:
382
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
402.244g/mol
Formal Charge:
0
Heavy Atom Count:
28
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
403.007g/mol
Monoisotopic Mass:
402.244g/mol
Rotatable Bond Count:
10
Topological Polar Surface Area:
15.7A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone. | European journal of pharmacology 20121205 |
| Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats. | Journal of cellular and molecular medicine 20121101 |
| Bepridil is effective and improves QOL in multidrug-resistant paroxysmal atrial fibrillation. | Journal of cardiovascular medicine (Hagerstown, Md.) 20121101 |
| Transmural dispersion of repolarization as a preclinical marker of drug-induced proarrhythmia. | Journal of cardiovascular pharmacology 20120801 |
| Effectiveness of amiodarone versus bepridil in achieving conversion to sinus rhythm in patients with persistent atrial fibrillation: a randomised trial. | Heart (British Cardiac Society) 20120701 |
| Combined effects of up- and downstream therapies on atrial fibrillation in a canine rapid stimulation model. | International journal of cardiology 20120531 |
| The relationship between the plasma concentration of bepridil and its efficacy in the treatment of atrial fibrillation in Japanese patients. | Biological & pharmaceutical bulletin 20120101 |
| [Series: Clinical study from Japan and its reflections; J-BAF study]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20110810 |
| Molecular dynamics and docking studies on cardiac troponin C. | Journal of biomolecular structure & dynamics 20110801 |
| An LC method for quantifying bepridil in human plasma using 1-naphthol as the internal standard. | Journal of chromatographic science 20110801 |
| In vitro and experimental therapeutic studies of the calcium channel blocker bepridil: detection of viable Leishmania (L.) chagasi by real-time PCR. | Experimental parasitology 20110601 |
| A computational and experimental approach to investigate bepridil binding with cardiac troponin. | The journal of physical chemistry. B 20110317 |
| Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110202 |
| Bepridil facilitates early termination of spiral-wave reentry in two-dimensional cardiac muscle through an increase of intercellular electrical coupling. | Journal of pharmacological sciences 20110101 |
| Clinical outcome in patients with paroxysmal or persistent atrial fibrillation receiving bepridil. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Repetitive evaluation of fibrillation cycle length predicts the efficacy of bepridil for interruption of long-lasting persistent atrial fibrillation. | International heart journal 20110101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Efficacy of low-dose bepridil for prevention of ventricular fibrillation in patients with Brugada syndrome with and without SCN5A mutation. | Journal of cardiovascular pharmacology 20101001 |
| Effects of bepridil versus E-4031 on transmural ventricular repolarization and inducibility of ventricular tachyarrhythmias in the dog. | Pacing and clinical electrophysiology : PACE 20100801 |
| Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100711 |
| Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100630 |
| Candesartan decreases type III procollagen-N-peptide levels and inflammatory marker levels and maintains sinus rhythm in patients with atrial fibrillation. | Journal of cardiovascular pharmacology 20100501 |
| Importance of morphological changes in T-U waves during bepridil therapy as a predictor of ventricular arrhythmic event. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Effect of bepridil in atrial fibrillation inducibility facilitated by vagal nerve stimulation. - Prevention of vagal nerve activation-induced shortening of the atrial action potential duration -. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Inhibition of Listeria monocytogenes infection by neurological drugs. | International journal of antimicrobial agents 20100301 |
| [Best strategy for the treatment of atrial fibrillation: reconsideration after randomized multicenter clinical trials in Japan]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100201 |
| Pharmacological cardioversion preceding left atrial ablation: bepridil predicts the clinical outcome following ablation in patients with persistent atrial fibrillation. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20091201 |
| Opposing effects of bepridil on ventricular repolarization in humans. Inhomogeneous prolongation of the action potential duration vs flattening of its restitution kinetics. | Circulation journal : official journal of the Japanese Circulation Society 20090901 |
| Two patients with bepridil-induced interstitial pneumonia. | Circulation journal : official journal of the Japanese Circulation Society 20090701 |
| Predicting the efficacy of antiarrhythmic agents for interrupting persistent atrial fibrillation according to spectral analysis of the fibrillation waves on the surface ECG. | Circulation journal : official journal of the Japanese Circulation Society 20090701 |
| Dose-response effects of bepridil in patients with persistent atrial fibrillation monitored with transtelephonic electrocardiograms: a multicenter, randomized, placebo-controlled,double-blind study (J-BAF Study). | Circulation journal : official journal of the Japanese Circulation Society 20090601 |
| Bepridil up-regulates cardiac Na+ channels as a long-term effect by blunting proteasome signals through inhibition of calmodulin activity. | British journal of pharmacology 20090601 |
| Does bepridil create a paradigm shift in the treatment of persistent atrial fibrillation? | Circulation journal : official journal of the Japanese Circulation Society 20090601 |
| Effect of compound plate composition on measurement of hERG current IC(50) using PatchXpress. | Journal of pharmacological and toxicological methods 20090101 |
| Gradual progression of interstitial pneumonia induced by bepridil. | Internal medicine (Tokyo, Japan) 20090101 |
| Beat-to-beat variability of repolarization differentiates the extent of torsadogenic potential of multi ion channel-blockers bepridil and amiodarone. | European journal of pharmacology 20081031 |
| Comparison of electropharmacological effects of bepridil and sotalol in halothane-anesthetized dogs. | Circulation journal : official journal of the Japanese Circulation Society 20080601 |
| Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm. | Circulation journal : official journal of the Japanese Circulation Society 20080501 |
| [Role of apoptosis in the kidney after reperfusion]. | Orvosi hetilap 20080217 |
| Inhomogenic effect of bepridil on atrial electrical remodeling in a canine rapid atrial stimulation model. | Circulation journal : official journal of the Japanese Circulation Society 20080201 |
| Combination therapy of renin angiotensin system inhibitors and bepridil is useful for maintaining sinus rhythm in patients with atrial fibrillation. | Journal of cardiology 20071201 |
| Relation of interleukin-6 and C-reactive protein levels to sinus maintenance after pharmacological cardioversion in persistent atrial fibrillation. | Journal of cardiovascular pharmacology 20070901 |
| Neuronal preconditioning with the antianginal drug, bepridil. | Journal of neurochemistry 20070801 |
| Efficacy and safety of the additional bepridil treatment in patients with atrial fibrillation refractory to class I antiarrhythmic drugs. | Circulation journal : official journal of the Japanese Circulation Society 20070801 |
| Bepridil reverses atrial electrical remodeling and L-type calcium channel downregulation in a canine model of persistent atrial tachycardia. | Journal of cardiovascular electrophysiology 20070701 |
| Involvement of Na+-Ca2+ exchanger on metabotropic glutamate receptor 1-mediated [Ca2+]i transients in rat cerebellar Purkinje neurons. | Neuroscience 20070425 |
| Na+/Ca2+ exchanger inhibitors modify the accumulation of tumor-diagnostic PET tracers in cancer cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070101 |
| Bepridil for drug-refractory ventricular tachyarrhythmias. | Internal medicine (Tokyo, Japan) 20070101 |
| Bepridil produces prominent bradycardia-dependent QT prolongation in patients with structural heart disease. | Journal of electrocardiology 20070101 |
| Proarrhythmic potential of reverse use-dependent drugs. | Journal of electrocardiology 20070101 |
| Elevation of intracellular ca(2+) concentration induced by hypoxia in retinal ganglion cells. | Japanese journal of ophthalmology 20070101 |
| Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs. | Journal of pharmacological and toxicological methods 20070101 |
| [Cardioversion of amiodarone-insensitive atrial fibrillation by bepridil in heart failure: two case reports]. | Journal of cardiology 20061201 |
| The influence of sodium-calcium exchange inhibitors on rabbit lens ion balance and transparency. | Experimental eye research 20061101 |
| Studies of the effect of ionomycin on the KCNQ4 channel expressed in Xenopus oocytes. | Biochemical and biophysical research communications 20060915 |
| Pharmacological activation and inhibition of Slack (Slo2.2) channels. | Neuropharmacology 20060901 |
| Pharmacological cardioversion of persistent atrial fibrillation with and without a history of drug-resistant paroxysmal atrial fibrillation. | Circulation journal : official journal of the Japanese Circulation Society 20060901 |
| Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization. | European journal of pharmacology 20060807 |
| Clinical evaluation of adverse effects during bepridil administration for atrial fibrillation and flutter. | Circulation journal : official journal of the Japanese Circulation Society 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Chronic hypoxia inhibits Na+/Ca2+ exchanger expression in cortical astrocytes. | Neuroreport 20060424 |
| [Strategy for cardiac arrhythmias in acute coronary syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20060401 |
| Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias. | Biological & pharmaceutical bulletin 20060301 |
| [Present status in and prospects for anti-arrhythmic drug therapy: How to use type III anti-arrhythmic agents]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060210 |
| [Clinical care for patients with possible Brugada syndrome]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060210 |
| Role of the Na+/Ca2+ exchanger in calcium homeostasis and human sperm motility regulation. | Cell motility and the cytoskeleton 20060201 |
| Bepridil inhibits sub-acute phase of atrial electrical remodeling in canine rapid atrial stimulation model. | Circulation journal : official journal of the Japanese Circulation Society 20060201 |
| Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. | The Journal of pharmacology and experimental therapeutics 20060101 |
| [A case of drug-induced pneumonitis due to bepridil]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20060101 |
| Recurrence of atrial fibrillation after internal cardioversion of persistent atrial fibrillation: prognostic importance of electrophysiologic parameters. | Circulation journal : official journal of the Japanese Circulation Society 20051201 |
| Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells. | The Journal of pharmacology and experimental therapeutics 20051001 |
| Practical application of guinea pig telemetry system for QT evaluation. | The Journal of toxicological sciences 20050801 |
| Voltage-dependent and frequency-independent inhibition of recombinant Cav3.2 T-type Ca2+ channel by bepridil. | Pharmacology 20050701 |
| Repolarization dynamics in patients with idiopathic ventricular fibrillation: pharmacological therapy with bepridil and disopyramide. | Journal of cardiovascular pharmacology 20050601 |
| Fibrillation cycle length and fibrillatory rate obtained from peak frequency of fibrillation waves. | The American journal of cardiology 20050415 |
| Conversion and maintenance of sinus rhythm by bepridil in patients with persistent atrial fibrillation. | Circulation journal : official journal of the Japanese Circulation Society 20050101 |
| Effects of Na+-Ca2+ exchanger activity on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolone-propionate-induced Ca2+ influx in cerebellar Purkinje neurons. | Neuroscience 20050101 |
| Influence of different calcic antagonists on the Caco-2 cell monolayer integrity or 'TEER, a measurement of toxicity?'. | European journal of drug metabolism and pharmacokinetics 20050101 |
| Drug-induced changes in fibrillation cycle length and organization index can predict chemical cardioversion of long-lasting atrial fibrillation with bepridil alone or in combination with aprindine. | Circulation journal : official journal of the Japanese Circulation Society 20041201 |
| Effects of blockers of Ca2+ channels and other ion channels on in vitro excystment of Paragonimus ohirai metacercariae induced by sodium cholate. | Parasitology research 20041101 |
| Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis. | Experimental neurology 20040901 |
| Maintenance of sinus rhythm and recovery of atrial mechanical function after cardioversion with bepridil or in combination with aprindine in long-lasting persistent atrial fibrillation. | Circulation journal : official journal of the Japanese Circulation Society 20040901 |
| Design, synthesis, and biological evaluation of novel T-Type calcium channel antagonists. | Bioorganic & medicinal chemistry letters 20040716 |
| Atrial fibrillatory frequency, atrial fibrillatory rate, or atrial cycle length--does it matter? | The American journal of cardiology 20040701 |
| Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats. | Neuropharmacology 20040301 |
| Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig. | European journal of pharmacology 20040220 |
| Bepridil block of recombinant human cardiac IKs current shows a time-dependent unblock. | Journal of cardiovascular pharmacology 20040201 |
| A case of bepridil induced interstitial pneumonitis. | Heart (British Cardiac Society) 20031201 |
| Sodium-calcium exchange influences the response to endothelin-1 in lens epithelium. | Cell calcium 20030901 |
| A case of sick sinus syndrome that developed torsades de pointes, pacing failure and sensing failure during administration of bepridil. | Japanese heart journal 20030901 |
| Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. | The American journal of cardiology 20030815 |
| Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration. | Annals of neurology 20030201 |
| Evaluation of the effect of bepridil on paroxysmal atrial fibrillation: relationship between efficacy and the f-f interval in surface ECG recordings. | Circulation journal : official journal of the Japanese Circulation Society 20030101 |
| Bepridil prevents paroxysmal atrial fibrillation by a class III antiarrhythmic drug effect. | Pacing and clinical electrophysiology : PACE 20030101 |
| Transepithelial transport of bepridil in the human intestinal cell line, Caco-2, using a 'dynamic model'. | European journal of drug metabolism and pharmacokinetics 20030101 |
| Beta-blocker decreases the increase in QT dispersion and transmural dispersion of repolarization induced by bepridil. | Circulation journal : official journal of the Japanese Circulation Society 20021101 |
| Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. | Annals of the New York Academy of Sciences 20021101 |
| Na(+)/Ca(2+) exchanger in porcine oocytes. | Biology of reproduction 20021001 |
| Possible role of calcium ions, calcium channels and calmodulin in excystation and metacystic development of Entamoeba invadens. | Parasitology research 20020901 |
| [Successful hybrid therapy combined with oral bepridil and ICD in a patient with amiodarone refractory life-threatening ventricular tachyarrhythmia associated with ischemic cardiomyopathy]. | Journal of UOEH 20020901 |
| Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. | The Journal of biological chemistry 20020823 |
| Assessment of pro-oxidant activity of foods by kinetic analysis of crocin bleaching. | Journal of agricultural and food chemistry 20020508 |
| Identification of radical scavengers in sweet grass (Hierochloe odorata). | Journal of agricultural and food chemistry 20020508 |
| On-line HPLC-DPPH screening method for evaluation of radical scavenging phenols extracted from apples (Malus domestica L.). | Journal of agricultural and food chemistry 20020424 |
| Antioxidant functions of selected allium thiosulfinates and S-alk(en)yl-L-cysteine sulfoxides. | Journal of agricultural and food chemistry 20020424 |
| Antioxidative activity and safety of the 50 ethanolic extract from red bean fermented by Bacillus subtilis IMR-NK1. | Journal of agricultural and food chemistry 20020410 |
| Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants. | Journal of agricultural and food chemistry 20020410 |
| Antioxidant properties of ferulic acid and its related compounds. | Journal of agricultural and food chemistry 20020327 |
| Free radical studies of ellagic acid, a natural phenolic antioxidant. | Journal of agricultural and food chemistry 20020327 |
| Free radical scavenging activity of red ginseng aqueous extracts. | Toxicology 20020320 |
| Free radical scavenging properties of wheat extracts. | Journal of agricultural and food chemistry 20020313 |
| Antioxidants from the bark of Burkea africana, an African medicinal plant. | Phytotherapy research : PTR 20020301 |
| Antioxidant capacities of ten edible North American plants. | Phytotherapy research : PTR 20020201 |
| Antioxidant enzymes and DPPH-radical scavenging activity in chilled and heat-shocked rice (Oryza sativa L.) seedlings radicles. | Journal of agricultural and food chemistry 20020130 |
| Antioxidant effects of 1,5-anhydro-D-fructose, a new natural sugar, in vitro. | Planta medica 20020101 |
| Role of Na(+)-Ca(2+) exchanger after traumatic or hypoxic/ischemic injury to spinal cord white matter. | The spine journal : official journal of the North American Spine Society 20020101 |
| A quinolone alkaloid with antioxidant activity from the aleurone layer of anthocyanin-pigmented rice. | Journal of natural products 20011201 |
| Inhibitory effect of bepridil on hKv1.5 channel current: comparison with amiodarone and E-4031. | European journal of pharmacology 20011102 |
| Antioxidant properties of methanolic extracts from several ear mushrooms. | Journal of agricultural and food chemistry 20011101 |
| Synthesis and in vitro studies of pyrone derivatives as scavengers of active oxygen species. | Arzneimittel-Forschung 20011101 |
| Scavenging of reactive oxygen species by chlorophyllin: an ESR study. | Free radical research 20011101 |
| Vasorelaxing and antioxidant constituents from Hernandia nymphaeifolia. | Planta medica 20011001 |
| Identification and antioxidant activity of novel chlorogenic acid derivatives from bamboo (Phyllostachys edulis). | Journal of agricultural and food chemistry 20011001 |
| Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber. | Journal of agricultural and food chemistry 20011001 |
| Scavenging of free radicals, antimicrobial, and cytotoxic activities of the Maillard reaction products of beta-lactoglobulin glycated with several sugars. | Journal of agricultural and food chemistry 20011001 |
| DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity of flavonoids obtained from some medicinal plants. | Biological & pharmaceutical bulletin 20011001 |
| Antioxidative components from the aerial parts of Lactuca scariola L. | Archives of pharmacal research 20011001 |
| Superoxide- and 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activities of soyasaponin beta g related to gallic acid. | Bioscience, biotechnology, and biochemistry 20011001 |
| Sorbicillinol, a key intermediate of bisorbicillinoid biosynthesis in Trichoderma sp. USF-2690. | Bioscience, biotechnology, and biochemistry 20011001 |
| Interaction of bepridil with the cardiac troponin C/troponin I complex. | FEBS letters 20010928 |
| Antiradical and antilipoperoxidative effects of some plant extracts used by Sri Lankan traditional medical practitioners for cardioprotection. | Phytotherapy research : PTR 20010901 |
| Two new diterpenoids from Plectranthus nummularius Briq. | Chemical & pharmaceutical bulletin 20010901 |
| Inhibition of Na+/Ca2+ exchange with KB-R7943 or bepridil diminished mineral deposition by osteoblasts. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801 |
| Phenolic constituents and antioxidant activity of an extract of Anthuriumversicolor leaves. | Journal of natural products 20010801 |
| Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia. | Journal of natural products 20010801 |
| Antioxidant principles from Bauhinia tarapotensis. | Journal of natural products 20010701 |
| [Bepridil inhibition on the delayed rectifier K+ currents in thyroxine induced hypertrophied guinea pig ventricular myocytes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010701 |
| Cyclooxygenase-inhibitory and antioxidant constituents of the aerial parts of Antirhea acutata. | Bioorganic & medicinal chemistry letters 20010618 |
| 2,2-Diphenyl-1-picrylhydrazyl hydrate, a stable free radical, is an alpha-glucosidase inhibitor. | Biological & pharmaceutical bulletin 20010601 |
| Alkaloids and flavonoids from peanut skins. | Planta medica 20010601 |
| Isolation and antioxidant activity of galloyl flavonol glycosides from the seashore plant, Pemphis acidula. | Bioscience, biotechnology, and biochemistry 20010601 |
| Effect of the antianginal drug bepridil on intracellular Ca2+ release and extracellular Ca2+ influx in human neutrophils. | International immunopharmacology 20010501 |
| A novel series of thromboxane A2 synthetase inhibitors with free radical scavenging and anti-peroxidative activities. | Chemical & pharmaceutical bulletin 20010501 |
| Radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl of ascorbic acid 2-glucoside (AA-2G) and 6-acyl-AA-2G. | Chemical & pharmaceutical bulletin 20010501 |
| Broussochalcone A, a potent antioxidant and effective suppressor of inducible nitric oxide synthase in lipopolysaccharide-activated macrophages. | Biochemical pharmacology 20010415 |
| KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology. | American journal of physiology. Cell physiology 20010401 |
| Ionic mechanisms of aglycemic axon injury in mammalian central white matter. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401 |
| A new antioxidant monoterpene glycoside, alpha-benzoyloxypaeoniflorin from Paeonia suffruticosa. | Archives of pharmacal research 20010401 |
| Blocking effect of bepridil on Na+/Ca2+ exchange current in guinea pig cardiac ventricular myocytes. | Japanese journal of pharmacology 20010401 |
| 1,1-Diphenyl-2-picrylhydrazyl radical-scavenging active compounds from greater cardamom (Amomum subulatum Roxb.). | Journal of nutritional science and vitaminology 20010401 |
| Expression and functional behavior of troponin C in soleus muscle fibers of rat after hindlimb unloading. | Journal of applied physiology (Bethesda, Md. : 1985) 20010301 |
| Relationship between effects of phenolic compounds on the generation of free radicals from lactoperoxidase-catalyzed oxidation of NAD(P)H or GSH and their DPPH scavenging ability. | Chemical & pharmaceutical bulletin 20010301 |
| Antioxidant activities of buckwheat hull extract toward various oxidative stress in vitro and in vivo. | Biological & pharmaceutical bulletin 20010301 |
| The antioxidant activity of the essential oils of Artemisia afra, Artemisia abyssinica and Juniperus procera. | Phytotherapy research : PTR 20010301 |
| Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method. | Phytotherapy research : PTR 20010301 |
| Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells. | Biochemical and biophysical research communications 20010223 |
| In vitro evaluation of the antioxidant activity and biomembrane interaction of the lazaroid U-74389G. | Life sciences 20010209 |
| New bis-catechols 5-lipoxygenase inhibitors. | Bioorganic & medicinal chemistry 20010201 |
| Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. | Atherosclerosis 20010101 |
| Antioxidant benzoylated flavan-3-ol glycoside from Celastrus orbiculatus. | Journal of natural products 20010101 |
| Effect of nilvadipine in weak acidic medium by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. | Arzneimittel-Forschung 20010101 |
| Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone. | Journal of Asian natural products research 20010101 |
| Screening of chemiluminescence constituents of cereals and DPPH radical scavenging activity of gamma-oryzanol. | Luminescence : the journal of biological and chemical luminescence 20010101 |
| Antioxidant activity of 5-alkoxymethyl-6-chromanols. | Redox report : communications in free radical research 20010101 |
| Assessment of antioxidant activity of some antileprotic drugs. | Arzneimittel-Forschung 20010101 |
| Electron spin resonance assessment of the antioxidant potential of medicinal plants. Part I. Contribution of anthocyanosides and flavonoids to the radical scavenging ability of fruit and herbal teas. | Acta poloniae pharmaceutica 20010101 |
| Evaluation of the absorption, excretion, and metabolism of the antihypertensive agent RWJ-26899 in male and female CR Wistar rats and Beagle dogs. | European journal of drug metabolism and pharmacokinetics 20010101 |
| Chalcones: structural requirements for antioxidant, estrogenic and antiproliferative activities. | Anticancer research 20010101 |
| [Bepridil: importance of serum level in treatment surveillance]. | Presse medicale (Paris, France : 1983) 20000401 |
| Propranolol and bepridil attenuating levothyroxine-induced rat cardiac hypertrophy and mitochondrial Ca2+ Mg(2+)-ATPase activity elevation. | Zhongguo yao li xue bao = Acta pharmacologica Sinica 19961101 |
| Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. | JAMA 19931201 |
| Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. | Arzneimittel-Forschung 19930301 |
| Safety profile of bepridil determined from clinical trials in chronic stable angina in the United States. | The American journal of cardiology 19920409 |
| Evaluation of bepridil efficacy by electrophysiologic testing in patients with recurrent ventricular tachycardia: comparison of two regimens. | Cardiovascular drugs and therapy 19920401 |
| Effects of bepridil and CERM 4205 (ORG 30701) on the relation between cardiac cycle length and QT duration in healthy volunteers. | The American journal of cardiology 19900901 |
| Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs. | Fundamental & clinical pharmacology 19870101 |
| Alterations in contrast medium-induced coronary reactive hyperemia after bepridil in patients with coronary artery disease. | American heart journal 19850201 |
| Bepridil for recurrent sustained ventricular tachycardias: assessment using electrophysiologic testing. | The American journal of cardiology 19840901 |
| Studies on the bradycardia induced by bepridil. | British journal of pharmacology 19820201 |
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