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7421-40-1 | CarbenoXolone Disodium Salt
CAS No: 7421-40-1 Catalog No: AG003OP7 MDL No:MFCD00079043
Product Description
Catalog Number:
AG003OP7
Chemical Name:
CarbenoXolone Disodium Salt
CAS Number:
7421-40-1
Molecular Formula:
C34H48Na2O7
Molecular Weight:
614.7203
MDL Number:
MFCD00079043
IUPAC Name:
disodium;(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxylatopropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
InChI:
InChI=1S/C34H50O7.2Na/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6;;/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40);;/q;2*+1/p-2/t21-,23-,24-,27+,30+,31-,32-,33+,34+;;/m0../s1
InChI Key:
BQENDLAVTKRQMS-SBBGFIFASA-L
SMILES:
O=C(OC1CCC2(C(C1(C)C)CCC1(C2C(=O)C=C2C1(C)CCC1(C2CC(C)(CC1)C(=O)[O-])C)C)C)CCC(=O)[O-].[Na+].[Na+]
EC Number:
231-044-0
UNII:
F1MP7242Z5
Properties
Complexity:
1190
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3
Defined Atom Stereocenter Count:
9
Defined Bond Stereocenter Count:
0
Exact Mass:
614.32g/mol
Formal Charge:
0
Heavy Atom Count:
43
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
614.731g/mol
Monoisotopic Mass:
614.32g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
124A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
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| Intracellular polyamines enhance astrocytic coupling. | Neuroreport 20121205 |
| Serotonin passes through myoendothelial gap junctions to promote pulmonary arterial smooth muscle cell differentiation. | American journal of physiology. Lung cellular and molecular physiology 20121101 |
| Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. | European journal of pharmacology 20120915 |
| Cardiac tissue slices with prolonged survival for in vitro drug safety screening. | Journal of pharmacological and toxicological methods 20120901 |
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| IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response. | American journal of physiology. Lung cellular and molecular physiology 20120901 |
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| Investigating channel blockers for the treatment of multiple sclerosis: considerations with mefloquine and carbenoxolone. | Journal of neuroimmunology 20120227 |
| Prostacyclin receptor-mediated ATP release from erythrocytes requires the voltage-dependent anion channel. | American journal of physiology. Heart and circulatory physiology 20120201 |
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| Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice. | Clinical and experimental pharmacology & physiology 20120101 |
| Susceptibility of glucocorticoids to colonic metabolism and pharmacologic intervention in the metabolism: implication for therapeutic activity of colon-specific glucocorticoid 21-sulfate sodium at the target site. | The Journal of pharmacy and pharmacology 20120101 |
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| Mechanisms of constitutive and ATP-evoked ATP release in neonatal mouse olfactory epithelium. | BMC neuroscience 20120101 |
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| HMGB1-carbenoxolone interactions: dynamics insights from combined nuclear magnetic resonance and molecular dynamics. | Chemistry, an Asian journal 20110502 |
| Spontaneous calcium oscillations during diastole in the whole heart: the influence of ryanodine reception function and gap junction coupling. | American journal of physiology. Heart and circulatory physiology 20110501 |
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| Protein kinase inhibitor as a potential candidate for epilepsy treatment. | Epilepsia 20110301 |
| A cholinergic-regulated circuit coordinates the maintenance and bi-stable states of a sensory-motor behavior during Caenorhabditis elegans male copulation. | PLoS genetics 20110301 |
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| Carbenoxolone blocks the light-evoked rise in intracellular calcium in isolated melanopsin ganglion cell photoreceptors. | PloS one 20110101 |
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| Pannexin-I/P2X 7 purinergic receptor channels mediate the release of cardioprotectants induced by ischemic pre- and postconditioning. | Journal of cardiovascular pharmacology and therapeutics 20100601 |
| Pectin-based bioadhesive delivery of carbenoxolone sodium for aphthous ulcers in oral cavity. | AAPS PharmSciTech 20100601 |
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| Effects of gap junction blockers on human neocortical synchronization. | Neurobiology of disease 20060601 |
| The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats. | Epilepsia 20060601 |
| Ischemia opens neuronal gap junction hemichannels. | Science (New York, N.Y.) 20060512 |
| Gap junction blockade does not alter eupnea or gasping in the juvenile rat. | Respiratory physiology & neurobiology 20060501 |
| Disruption of gap junctional communication within the ovarian follicle induces oocyte maturation. | Endocrinology 20060501 |
| Glutamate uptake block triggers deadly rhythmic bursting of neonatal rat hypoglossal motoneurons. | The Journal of physiology 20060415 |
| 11Beta-hydroxysteroid dehydrogenase type 2 and the regulation of surfactant protein A by dexamethasone metabolites. | American journal of physiology. Endocrinology and metabolism 20060401 |
| The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. | Experimental brain research 20060401 |
| Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy. | Epilepsy research 20060401 |
| The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate. | Biochimica et biophysica acta 20060401 |
| Role of gap junction in the expression of morphine-induced antinociception. | European journal of pharmacology 20060327 |
| Block of inferior olive gap junctional coupling decreases Purkinje cell complex spike synchrony and rhythmicity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208 |
| Inhibition of 11beta-hydroxysteroid dehydrogenase eliminates impaired glucocorticoid suppression and induces apoptosis in corticotroph tumor cells. | Endocrinology 20060201 |
| Increased levels of cyclins D1 and D3 after inhibition of gap junctional communication in astrocytes. | Journal of neurochemistry 20060201 |
| Aging is associated with an increase in dye coupling and in gap junction number in satellite glial cells of murine dorsal root ganglia. | Neuroscience 20060101 |
| Corticosterone transfer and metabolism in the dually perfused rat placenta: effect of 11beta-hydroxysteroid dehydrogenase type 2. | Placenta 20060101 |
| Carbenoxolone does not cross the blood brain barrier: an HPLC study. | BMC neuroscience 20060101 |
| Role of gap junctional coupling in astrocytic networks in the determination of global ischaemia-induced oxidative stress and hippocampal damage. | The European journal of neuroscience 20060101 |
| Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional coupling. | The European journal of neuroscience 20060101 |
| Metabolic effects of carbenoxolone in rat liver. | Journal of biochemical and molecular toxicology 20060101 |
| Synergistic center-surround receptive field model of monkey H1 horizontal cells. | Journal of vision 20051229 |
| Sex-specific effects of prenatal low-protein and carbenoxolone exposure on renal angiotensin receptor expression in rats. | Hypertension (Dallas, Tex. : 1979) 20051201 |
| Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated. | Molecular and cellular endocrinology 20051124 |
| Induction of sharp wave-ripple complexes in vitro and reorganization of hippocampal networks. | Nature neuroscience 20051101 |
| The spread of apoptosis through gap-junctional channels in BHK cells transfected with Cx32. | Apoptosis : an international journal on programmed cell death 20051001 |
| Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes. | European journal of clinical investigation 20051001 |
| Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia. | Stroke 20051001 |
| Quinine, a blocker of neuronal cx36 channels, suppresses seizure activity in rat neocortex in vivo. | Epilepsia 20051001 |
| Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice). | Neuropharmacology 20050901 |
| The effects of carbenoxolone, a semisynthetic derivative of glycyrrhizinic acid, on peripheral and central ischemia-reperfusion injuries in the skeletal muscle and hippocampus of rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20050901 |
| Rapid endothelial cell-selective loading of connexin 40 antibody blocks endothelium-derived hyperpolarizing factor dilation in rat small mesenteric arteries. | Circulation research 20050819 |
| Electrical coupling in sustentacular cells of the mouse olfactory epithelium. | Journal of neurophysiology 20050801 |
| Intercellular communications within the rat anterior pituitary XII: immunohistochemical and physiological evidences for the gap junctional coupling of the folliculo-stellate cells in the rat anterior pituitary. | Tissue & cell 20050801 |
| Loss of connexin36 increases retinal cell vulnerability to secondary cell loss. | The European journal of neuroscience 20050801 |
| Gastroprotective effect of Astragaloside IV: role of prostaglandins, sulfhydryls and nitric oxide. | The Journal of pharmacy and pharmacology 20050801 |
| Mono- and dual-frequency fast cerebellar oscillation in mice lacking parvalbumin and/or calbindin D-28k. | The European journal of neuroscience 20050801 |
| Inner and outer retinal pathways both contribute to surround inhibition of salamander ganglion cells. | The Journal of physiology 20050601 |
| Carbenoxolone induces oxidative stress in liver mitochondria, which is responsible for transition pore opening. | Endocrinology 20050501 |
| Rhythmic expression of clock-controlled genes in retinal photoreceptors is sensitive to 18-beta-glycyrrhetnic acid and 18-alpha-glycyrrhetnic acid-3-hemisuccinate. | Brain research. Molecular brain research 20050427 |
| Ripple activity in the dentate gyrus of dishinibited hippocampus-entorhinal cortex slices. | Journal of neuroscience research 20050401 |
| Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. | Journal of neurochemistry 20050301 |
| Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. | Diabetes 20050301 |
| The effects of carbenoxolone on spatial learning in the Morris water maze task in rats. | Medical science monitor : international medical journal of experimental and clinical research 20050301 |
| K(+)-induced vasodilation in the rat kidney is dependent on the endothelium and activation of K+ channels. | European journal of pharmacology 20050131 |
| Intercellular communication: role of gap junctions in establishing the pattern of ATP-elicited Ca2+ oscillations and Ca2+-dependent currents in freshly isolated aortic smooth muscle cells. | Cell calcium 20050101 |
| Fast cerebellar oscillation associated with ataxia in a mouse model of Angelman syndrome. | Neuroscience 20050101 |
| Renal humoral modulation of skeletal muscle tone in mice: implications for 'the pulmonary-renal cascade'. | Indian journal of physiology and pharmacology 20050101 |
| Ventilatory effects of gap junction blockade in the RTN in awake rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20041201 |
| Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs). | Neuropharmacology 20041201 |
| Rhythms, synchrony and electrical coupling in the Locus coeruleus. | Respiratory physiology & neurobiology 20041115 |
| Patterns of cell-cell coupling in embryonic spinal cord studied via ballistic delivery of gap-junction-permeable dyes. | The Journal of comparative neurology 20040920 |
| Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. | The Journal of biological chemistry 20040917 |
| Ventilatory effects of gap junction blockade in the NTS in awake rats. | Respiratory physiology & neurobiology 20040915 |
| Developmental changes in transmission of respiratory rhythm in the rat. | Respiratory physiology & neurobiology 20040915 |
| Electrical coupling underlies theta oscillations recorded in hippocampal formation slices. | Brain research 20040903 |
| Coexistence of gamma and high-frequency oscillations in rat medial entorhinal cortex in vitro. | The Journal of physiology 20040901 |
| Effects of carbenoxolone on alveolar fluid clearance and lung inflammation in the rat. | Critical care medicine 20040901 |
| Spinal gap junctions: potential involvement in pain facilitation. | The journal of pain : official journal of the American Pain Society 20040901 |
| Carbenoxolone inhibition of voltage-gated Ca channels and synaptic transmission in the retina. | Journal of neurophysiology 20040801 |
| Gap junctions are required for trophoblast proliferation in early human placental development. | Placenta 20040801 |
| Electrotonic coupling between stratum oriens interneurones in the intact in vitro mouse juvenile hippocampus. | The Journal of physiology 20040801 |
| 11beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone stimulates chorionic gonadotropin secretion from human term cytotrophoblast cells differentiated in vitro. | American journal of reproductive immunology (New York, N.Y. : 1989) 20040801 |
| Permeability to water in a tight epithelium: possible modulating action of gap junctions. | Canadian journal of physiology and pharmacology 20040601 |
| Endothelin-1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: relationship with gap junctional communication. | Journal of neurochemistry 20040501 |
| Ca(2+) signalling and gap junction coupling within and between pigment epithelium and neural retina in the developing chick. | The European journal of neuroscience 20040501 |
| The classical receptive field surround of primate parasol ganglion cells is mediated primarily by a non-GABAergic pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040414 |
| Attenuation of gap-junction-mediated signaling facilitated anesthetic effect of sevoflurane in the central nervous system of rats. | Anesthesia and analgesia 20040301 |
| Influence of carbenoxolone on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice. | European journal of pharmacology 20040119 |
| The hippocampal intrinsic network oscillator. | The Journal of physiology 20040101 |
| Ultrastructure of junction areas between neurons and astrocytes in rat supraoptic nuclei. | World journal of gastroenterology 20040101 |
| Physiological response properties of displaced amacrine cells of the adult ferret retina. | Visual neuroscience 20040101 |
| Carbenoxolone blockade of neuronal network activity in culture is not mediated by an action on gap junctions. | The Journal of physiology 20031215 |
| Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo. | Epilepsia 20031201 |
| Contribution of connexin26 to electrical feedback inhibition in the turtle retina. | The Journal of comparative neurology 20031124 |
| Gap junction blockade with carbenoxolone differentially affects fictive breathing in larval and adult bullfrogs. | Respiratory physiology & neurobiology 20031114 |
| Carbenoxolone inhibits DNA synthesis and collagen gene expression in rat hepatic stellate cells in culture. | Journal of hepatology 20031101 |
| Conduction slowing by the gap junctional uncoupler carbenoxolone. | Cardiovascular research 20031101 |
| Synaptic and non-synaptic mechanisms of amygdala recruitment into temporolimbic epileptiform activities. | The European journal of neuroscience 20031101 |
| Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031029 |
| Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. | Journal of neurochemistry 20030801 |
| Gap junctions mediate bystander cell death in developing retina. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030723 |
| Increased collecting duct urea transporter expression in Dahl salt-sensitive rats. | American journal of physiology. Renal physiology 20030701 |
| Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension. | QJM : monthly journal of the Association of Physicians 20030701 |
| Gap junctional coupling in the olfactory organ of zebrafish embryos. | Brain research. Developmental brain research 20030612 |
| Comparative pepstatin inhibition studies on individual human pepsins and pepsinogens 1,3 and 5(gastricsin) and pig pepsin A. | Journal of enzyme inhibition and medicinal chemistry 20030601 |
| Dexamethasone upregulates 11beta-hydroxysteroid dehydrogenase type 2 in BEAS-2B cells. | American journal of respiratory and critical care medicine 20030501 |
| Carbenoxolone accelerates maturation of rat intestine. | Pediatric research 20030501 |
| Functional hemichannels in astrocytes: a novel mechanism of glutamate release. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501 |
| Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases? | Archives of biochemistry and biophysics 20030415 |
| Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats. | The Journal of pharmacology and experimental therapeutics 20030401 |
| Does ICC pacing require functional gap junctions between ICC and smooth muscle in mouse intestine? | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20030401 |
| Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. | Journal of neurophysiology 20030401 |
| Cl- flux through a non-selective, stretch-sensitive conductance influences the outer hair cell motor of the guinea-pig. | The Journal of physiology 20030315 |
| Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. | Endocrinology 20030301 |
| Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20030101 |
| Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat. | Journal of neurophysiology 20030101 |
| Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice. | BMC pharmacology 20030101 |
| Excitatory GABA input directly drives seizure-like rhythmic synchronization in mature hippocampal CA1 pyramidal cells. | Neuroscience 20030101 |
| Desynchronisation of spontaneously recurrent experimental seizures proceeds with a single rhythm. | Neuroscience 20030101 |
| The gap junction blockers carbenoxolone and 18beta-glycyrrhetinic acid antagonize cone-driven light responses in the mouse retina. | Visual neuroscience 20030101 |
| Involvement of gap junctions in bradykinin-induced relaxation of bovine pulmonary supernumerary arteries before and after inhibition of nitric oxide/guanylate cyclase. | Clinical science (London, England : 1979) 20021201 |
| A role for electrotonic coupling in the striatum in the expression of dopamine receptor-mediated stereotypies. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021201 |
| Pharmacological enhancement of hemi-gap-junctional currents in Xenopus oocytes. | Journal of neuroscience methods 20021115 |
| Synaptic activation of hypoglossal respiratory motorneurons during inspiration in rats. | Neuroscience letters 20021108 |
| Aldosterone inhibits HCO absorption via a nongenomic pathway in medullary thick ascending limb. | American journal of physiology. Renal physiology 20021001 |
| Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids. | Biology of reproduction 20021001 |
| Anticonvulsant actions of gap junctional blockers in an in vitro seizure model. | Journal of neurophysiology 20021001 |
| The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women. | British journal of pharmacology 20020801 |
| Critical role of gap junctions in endothelium-dependent hyperpolarization in rat mesenteric arteries. | Clinical and experimental pharmacology & physiology 20020701 |
| Cortisol-mediated potentiation of uterine artery contractility: effect of pregnancy. | American journal of physiology. Heart and circulatory physiology 20020701 |
| [Determination of furazolidone, carbenoxolone sodium and berberine hydrochloride in wei kang tablets by reversed-phase high performance liquid chromatography(RP-HPLC)]. | Se pu = Chinese journal of chromatography 20020701 |
| Follicle-stimulating hormone induces a gap junction-dependent dynamic change in [cAMP] and protein kinase a in mammalian oocytes. | Developmental biology 20020615 |
| Antiulcerogenic activity of some sesquiterpene lactones isolated from Artemisia annua. | Planta medica 20020601 |
| Regulation of cultured rat hepatocyte proliferation by stellate cells. | Journal of hepatology 20020501 |
| Ischemia-induced brain damage depends on specific gap-junctional coupling. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401 |
| Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020201 |
| Blocked gap junctional coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures. | Journal of neuropathology and experimental neurology 20020201 |
| Glycyrrhetinic derivatives inhibit hyperpolarization in endothelial cells of guinea pig and rat arteries. | American journal of physiology. Heart and circulatory physiology 20020101 |
| Distinguishing the activities of 11beta-hydroxysteroid dehydrogenases in vivo using isotopically labeled cortisol. | The Journal of clinical endocrinology and metabolism 20020101 |
| Gap-junctional communication in mouse cumulus-oocyte complexes: implications for the mechanism of meiotic maturation. | Reproduction (Cambridge, England) 20020101 |
| Properties and origin of spikelets in thalamocortical neurones in vitro. | Neuroscience 20020101 |
| Axonal gap junctions between principal neurons: a novel source of network oscillations, and perhaps epileptogenesis. | Reviews in the neurosciences 20020101 |
| Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex. | Neuroscience 20020101 |
| Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion. | Journal of medicinal food 20020101 |
| Human adipose tissue under in vitro inhibition of 11beta-hydroxysteroid dehydrogenase type 1: differentiation and metabolism changes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101 |
| Gap junctions between interneuron dendrites can enhance synchrony of gamma oscillations in distributed networks. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201 |
| Carbenoxolone, a new inducer of heat shock protein 70. | Life sciences 20011102 |
| Modulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity in Ishikawa cells is associated with changes in cellular proliferation. | Molecular and cellular endocrinology 20011025 |
| Axo-axonal coupling. a novel mechanism for ultrafast neuronal communication. | Neuron 20010913 |
| Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? | Neuropharmacology 20010901 |
| Loss of correlated motor neuron activity during synaptic competition at developing neuromuscular synapses. | Neuron 20010816 |
| In vivo inhibition of renal 11beta-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption. | Clinical science (London, England : 1979) 20010801 |
| Expression and putative role of 11 beta-hydroxysteroid dehydrogenase isozymes within the human eye. | Investigative ophthalmology & visual science 20010801 |
| Gap junctions synchronize the firing of inhibitory interneurons in guinea pig hippocampus. | Brain research 20010713 |
| Hemichannel-mediated inhibition in the outer retina. | Science (New York, N.Y.) 20010511 |
| Optical recording of spreading depression in rat neocortical slices. | Brain research 20010420 |
| Second messenger modulation of electrotonic coupling between region CA3 pyramidal cell axons in the rat hippocampus. | Neuroscience letters 20010302 |
| Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro. | Journal of neurophysiology 20010301 |
| Immortalized gonadotropin-releasing hormone neurons (GT1-7 cells) exhibit synchronous bursts of action potentials. | Neuroendocrinology 20010301 |
| A possible role for gap junctions in generation of very fast EEG oscillations preceding the onset of, and perhaps initiating, seizures. | Epilepsia 20010201 |
| Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung. | Molecular and cellular endocrinology 20010122 |
| Searching for the physiological function of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies of substrate specificity and expression analysis. | Molecular and cellular endocrinology 20010122 |
| Distal tubular electrolyte transport during inhibition of renal 11beta-hydroxysteroid dehydrogenase. | American journal of physiology. Renal physiology 20010101 |
| How to close a gap junction channel. Efficacies and potencies of uncoupling agents. | Methods in molecular biology (Clifton, N.J.) 20010101 |
| Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling. | Neuroscience 20010101 |
| Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus. | Neuroscience 20010101 |
| A neuroprotective role for gap junctions. | Cell communication & adhesion 20010101 |
| The effect of cicloxolone sodium on the replication in cultured cells of adenovirus type 5, reovirus type 3, poliovirus type 1, two bunyaviruses and Semliki Forest virus. | The Journal of general virology 19920201 |
| Stridor due to drug-induced hypokalaemic alkalosis. | The Journal of laryngology and otology 19870201 |
| Drug-induced hypertension: pathogenesis and management. | Drugs 19760101 |
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