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71376-97-1 | guanosine 5'-O-(2-thiodiphosphate)
CAS No: 71376-97-1 Catalog No: AG00FQL4 MDL No:
Product Description
Catalog Number:
AG00FQL4
Chemical Name:
guanosine 5'-O-(2-thiodiphosphate)
CAS Number:
71376-97-1
IUPAC Name:
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydroxyphosphinothioyl hydrogen phosphate
InChI:
InChI=1S/C10H15N5O10P2S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChI Key:
QJXJXBXFIOTYHB-UUOKFMHZSA-N
Properties
Complexity:
765
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
4
Defined Bond Stereocenter Count:
0
Exact Mass:
459.001g/mol
Formal Charge:
0
Heavy Atom Count:
28
Hydrogen Bond Acceptor Count:
13
Hydrogen Bond Donor Count:
7
Isotope Atom Count:
0
Molecular Weight:
459.263g/mol
Monoisotopic Mass:
459.001g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
263A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.9
Literature
| Title | Journal |
|---|---|
| Role for protein kinase C in controlling Aplysia bag cell neuron excitability. | Neuroscience 20110414 |
| Direct interaction between Rab3D and the polymeric immunoglobulin receptor and trafficking through regulated secretory vesicles in lacrimal gland acinar cells. | American journal of physiology. Cell physiology 20080301 |
| Angiotensin II inhibits insulin-induced actin stress fiber formation and glucose uptake via ERK1/2. | The journal of medical investigation : JMI 20070201 |
| Tonic enhancement of endocannabinoid-mediated retrograde suppression of inhibition by cholinergic interneuron activity in the striatum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070117 |
| Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors. | The Journal of physiology 20060615 |
| Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages. | Atherosclerosis 20060601 |
| Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling. | Neuropharmacology 20051201 |
| Angiotensin II inhibits bTREK-1 K+ channels in adrenocortical cells by separate Ca2+- and ATP hydrolysis-dependent mechanisms. | The Journal of biological chemistry 20050902 |
| Guanine derivatives modulate L-glutamate uptake into rat brain synaptic vesicles. | Neurochemistry international 20040501 |
| Distinct regulation of expressed calcium channels 2.3 in Xenopus oocytes by direct or indirect activation of protein kinase C. | Brain research 20030411 |
| Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons. | Restorative neurology and neuroscience 20030101 |
| PF4, a FMRFamide-related peptide, gates low-conductance Cl(-) channels in Ascaris suum. | European journal of pharmacology 20021205 |
| G protein-independent activation of an inward Na(+) current by muscarinic receptors in mouse pancreatic beta-cells. | The Journal of biological chemistry 20021011 |
| Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. | Journal of neurophysiology 20020301 |
| Modulation by 5-hydroxytryptamine of nicotinic acetylcholine responses recorded from an identified cockroach (Periplaneta americana) motoneuron. | The European journal of neuroscience 20020201 |
| Calcium-G protein interactions in the regulation of macrophage secretion. | The Journal of biological chemistry 20011005 |
| Characterization of outward currents induced by 5-HT in neurons of rat dorsolateral septal nucleus. | Journal of neurophysiology 20010401 |
| Serine/threonine protein phosphatases and synaptic inhibition regulate the expression of cholinergic-dependent plateau potentials. | Journal of neurophysiology 20010301 |
| The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. | Circulation research 20010216 |
| Contribution of guanine nucleotide regulatory proteins to prostaglandin hyperalgesia in the rat. | Brain research 19890717 |
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