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70-78-0 | L-Tyrosine, 3-iodo-
CAS No: 70-78-0 Catalog No: AG0031A9 MDL No:MFCD00002608
Product Description
Catalog Number:
AG0031A9
Chemical Name:
L-Tyrosine, 3-iodo-
CAS Number:
70-78-0
Molecular Formula:
C9H10INO3
Molecular Weight:
307.0851
MDL Number:
MFCD00002608
IUPAC Name:
(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid
InChI:
InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
InChI Key:
UQTZMGFTRHFAAM-ZETCQYMHSA-N
SMILES:
OC(=O)[C@H](Cc1ccc(c(c1)I)O)N
EC Number:
200-744-8
UNII:
FRQ98U4U27
Properties
Complexity:
212
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
306.971g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
307.087g/mol
Monoisotopic Mass:
306.971g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
83.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.1
Literature
| Title | Journal |
|---|---|
| Speciation of the bio-available iodine and bromine forms in edible seaweed by high performance liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry. | Analytica chimica acta 20121001 |
| The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats. | Croatian medical journal 20120601 |
| Dopamine modulates metabolic rate and temperature sensitivity in Drosophila melanogaster. | PloS one 20120101 |
| Dopamine modulates the rest period length without perturbation of its power law distribution in Drosophila melanogaster. | PloS one 20120101 |
| Effects of halogenation on tyrosine phosphorylation and peptide binding to the SRC homology 2 domain of lymphocyte-specific protein tyrosine kinase. | Biological & pharmaceutical bulletin 20120101 |
| Multiple tyrosine metabolites are GPR35 agonists. | Scientific reports 20120101 |
| Ih current is necessary to maintain normal dopamine fluctuations and sleep consolidation in Drosophila. | PloS one 20120101 |
| Catecholamines up integrates dopamine synthesis and synaptic trafficking. | Journal of neurochemistry 20111201 |
| Dissecting cell signaling pathways with genetically encoded 3-iodo-L-tyrosine. | Chembiochem : a European journal of chemical biology 20110211 |
| Synthesis and characterization of 3-[131I]iodo-L-tyrosine grafted Fe3O4@SiO2 nanocomposite for single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). | Journal of nanoscience and nanotechnology 20110201 |
| Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships. | Bioorganic & medicinal chemistry 20101101 |
| Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis. | Aquatic toxicology (Amsterdam, Netherlands) 20100601 |
| Genetic encoding of non-natural amino acids in Drosophila melanogaster Schneider 2 cells. | Protein science : a publication of the Protein Society 20100301 |
| A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. | PloS one 20100101 |
| Dietary modulation of Drosophila sleep-wake behaviour. | PloS one 20100101 |
| Structural Aspects of Phenylalanylation and Quality Control in Three Major Forms of Phenylalanyl-tRNA Synthetase. | Journal of amino acids 20100101 |
| Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells. | Toxicology and applied pharmacology 20091115 |
| A mammalian reductive deiodinase has broad power to dehalogenate chlorinated and brominated substrates. | Journal of the American Chemical Society 20091014 |
| Ancient tRNA synthetase meets modern structural biology. | Structure (London, England : 1993) 20090311 |
| Genetic encoding of 3-iodo-L-tyrosine in Escherichia coli for single-wavelength anomalous dispersion phasing in protein crystallography. | Structure (London, England : 1993) 20090311 |
| Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration. | PloS one 20090101 |
| Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism. | The Journal of clinical endocrinology and metabolism 20081201 |
| Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. | Journal of medicinal chemistry 20080724 |
| Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease. | Journal of neuroinflammation 20080101 |
| Interaction of dopamine, female pheromones, locomotion and sex behavior in Drosophila melanogaster. | Journal of insect physiology 20080101 |
| Drosophila dopamine synthesis pathway genes regulate tracheal morphogenesis. | Developmental biology 20070801 |
| Chiral discrimination of D- and L-amino acids using iodinated tyrosines as chiral references: effect of iodine substituent. | Journal of the American Society for Mass Spectrometry 20070801 |
| Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells. | Toxicology and applied pharmacology 20070615 |
| Site-specific incorporation of non-natural amino acids into proteins in mammalian cells with an expanded genetic code. | Nature protocols 20060101 |
| Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. | Bioinorganic chemistry and applications 20060101 |
| The diazo route to diazonamide A: studies on the tyrosine-derived fragment. | Organic & biomolecular chemistry 20051021 |
| Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine. | The Journal of organic chemistry 20050902 |
| Effects of dopamine on juvenile hormone metabolism and fitness in Drosophila virilis. | Journal of insect physiology 20050901 |
| Development of a validated HPLC method for the determination of iodotyrosines and iodothyronines in pharmaceuticals and biological samples using solid phase extraction. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050105 |
| Sensitized photooxidation of thyroidal hormones. Evidence for heavy atom effect on singlet molecular oxygen [O2(1Deltag)]-mediated photoreactions. | Photochemistry and photobiology 20050101 |
| Cause of mortality in insects under severe stress. | European journal of biochemistry 20030801 |
| Use of a boroxazolidone complex of 3-iodo-L-tyrosine for palladium-catalyzed cross-coupling. | The Journal of organic chemistry 20030221 |
| Aromatic amino acids and their derivatives as ligands for the isolation of aspartic proteinases. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020425 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: characterization by ESR spin-trapping, HPLC and MS. | The Biochemical journal 20020415 |
| The effects of dopamine synthesis inhibitors and dopamine antagonists on regeneration in the hydra Hydra attenuata. | Neuroscience and behavioral physiology 20020101 |
| Changing the amino acid specificity of yeast tyrosyl-tRNA synthetase by genetic engineering. | Journal of biochemistry 20010901 |
| Update on intrathyroidal iodine metabolism. | Thyroid : official journal of the American Thyroid Association 20010501 |
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