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69388-84-7

69388-84-7 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI)

CAS No: 69388-84-7 Catalog No: AG0039LX MDL No:MFCD01750374

Product Description

Catalog Number:
AG0039LX
Chemical Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI)
CAS Number:
69388-84-7
Molecular Formula:
C8H10NNaO5S
Molecular Weight:
255.2235
MDL Number:
MFCD01750374
IUPAC Name:
sodium;(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChI:
InChI=1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
InChI Key:
NKZMPZCWBSWAOX-IBTYICNHSA-M
SMILES:
[O-]C(=O)[C@@H]1N2C(=O)C[C@H]2S(=O)(=O)C1(C)C.[Na+]
EC Number:
273-984-4
UNII:
DKQ4T82YE6

Properties

Complexity:
452  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
255.018g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
255.22g/mol
Monoisotopic Mass:
255.018g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
103A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

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The value of chemoprophylaxis against Enterococcus species in elective cholecystectomy: a randomized study of cefuroxime vs ampicillin-sulbactam. Archives of surgery (Chicago, Ill. : 1960) 20061201
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[Clinical and pharmacoeconomic perspective use of amoxicillin/sulbactam in the treatment of extra-hospital pneumonia]. Voenno-meditsinskii zhurnal 20061101
Internal jugular vein thrombosis associated with acute mastoiditis in a pediatric age. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20061001
[Case of anaphylactic shock induced by an antibiotic after induction of anesthesia]. Masui. The Japanese journal of anesthesiology 20061001
Liquid chromatographic method for the simultaneous determination of imipenem and sulbactam in mouse plasma. Journal of chromatographic science 20061001
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Acute iliopsoas and adductor brevis abscesses presenting with proximal leg muscle weakness. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060601
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Salmonella group C necrotizing fasciitis: a case report and review of the literature. Diagnostic microbiology and infectious disease 20060401
A series of systematic reviews to inform a decision analysis for sampling and treating infected diabetic foot ulcers. Health technology assessment (Winchester, England) 20060401
Synergy of arbekacin-based combinations against vancomycin hetero-intermediate Staphylococcus aureus. Journal of Korean medical science 20060401
Cefoperazone / sulbactam induced hyponatremia. Indian journal of medical sciences 20060401
Application of 2-acetylbutyrolactone to spectrofluorimetry: fluorescence properties of Schiff bases derived from 2-acetylbutyrolactone and spectrofluorimetric determination of primary amine-containing compounds. Journal of pharmaceutical and biomedical analysis 20060318
A new fractional wavelet approach for the simultaneous determination of ampicillin sodium and sulbactam sodium in a binary mixture. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060301
The simultaneous occurrence of contact urticaria from sulbactam and allergic contact dermatitis from ampicillin in a nurse. Contact dermatitis 20060301
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Actinomycotic inflammatory disease and misdiagnosis of ovarian cancer. A case report. Anticancer research 20060101
Review of pharmacokinetic, pharmacodynamic and clinical studies with a modern combination of amoxicillin/sulbactam. Chemotherapy 20060101
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Ampicillin-sulbactam versus amoxycillin in quadruple therapy for Helicobacter pylori eradication: a preliminary study. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20060101
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Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. The Indian journal of medical research 20051101
High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase. The Journal of biological chemistry 20051014
Variceal bleeding in portal hypertension: bacterial infection and comparison of efficacy of intravenous and per-oral application of antibiotics--a randomized trial. European journal of gastroenterology & hepatology 20051001
Pharmaceutical cost comparison analysis of antimicrobial use for surgical prophylaxis on gastrectomy patients in a tertiary care hospital. Chemotherapy 20051001
Amoxicillin-sulbactam versus amoxicillin-clavulanic acid for the treatment of non-recurrent-acute otitis media in Argentinean children. International journal of pediatric otorhinolaryngology 20050901
Septic arthritis secondary to fusobacterium necrophorum in a 4-year-old girl: case report and review of the literature. The Pediatric infectious disease journal 20050901
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In vitro synergy test of meropenem and sulbactam against clinical isolates of Acinetobacter baumannii. Diagnostic microbiology and infectious disease 20050801
[Dynamic analysis of drug resistance of Pseudomonas aeruginosa in laboratory and clinical two-drug regimen]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801
Piperacillin-sulbactam versus piperacillin-tazobactam: a multicentre, randomised, single-blind, controlled clinical trial. International journal of antimicrobial agents 20050701
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[Two leptospirosis cases and review of the national literature]. Mikrobiyoloji bulteni 20050701
Compatibility of tramadol hydrochloride injection with selected drugs and solutions. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050615
Treatment of childhood complicated community-acquired pneumonia with amoxicillin/sulbactam. Journal of chemotherapy (Florence, Italy) 20050601
Peritonsillar abscess: a comparison of outpatient i.m. clindamycin and inpatient i.v. ampicillin/sulbactam following needle aspiration. Ear, nose, & throat journal 20050601
The coexistence of hepatitis A and infectious mononucleosis. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20050601
Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp. International journal of antimicrobial agents 20050501
Pharmacokinetics of an ampicillin-sulbactam combination after intravenous and intramuscular administration to neonatal calves. Veterinary journal (London, England : 1997) 20050501
Antibiotic prophylaxis of early onset pneumonia in critically ill comatose patients. A randomized study. Intensive care medicine 20050401
Reappraisal of clindamycin IV monotherapy for treatment of mild-to-moderate aspiration pneumonia in elderly patients. Chest 20050401
Pulmonary abscess due to leflunomide use in rheumatoid arthritis: a case report. Rheumatology international 20050301
Effect of amoxicillin sulbactam in threatened preterm labour with intact membranes: a randomised controlled trial. European journal of obstetrics, gynecology, and reproductive biology 20050301
Response of visual loss in allergic fungal sinusitis to oral corticosteroids. The Annals of otology, rhinology, and laryngology 20050301
A case of right-side infective endocarditis with ventricular septal defect. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20050301
[Survey of the utilization and adverse effects of antibacterial drugs in patients admitted for respiratory diseases]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050201
Activities of various beta-lactams and beta-lactam/beta-lactamase inhibitor combinations against Acinetobacter baumannii and Acinetobacter DNA group 3 strains. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050101
Enterococcal meningitis caused by Enterococcus casseliflavus. First case report. BMC infectious diseases 20050101
Effect of bovine lactoferrin on the MICs of ampicillin/sulbactam (UNASYN), amoxicillin/clavulanic acid (Augmentin), ticarcillin clavulanate (Timentin), and piperacillin-tazobactam (ZOSYN), against clinical and environmental isolates of motile Aeromonas. The Journal of the American Osteopathic Association 20050101
Treatment of pan-drug resistant Acinetobacter baumannii. Scandinavian journal of infectious diseases 20050101
An open-label, randomized study comparing efficacy and safety of intravenous piperacillin/tazobactam and ampicillin/sulbactam for infected diabetic foot ulcers. Surgical infections 20050101
A 2-year-old girl with Stevens--Johnson syndrome/toxic epidermal necrolysis treated with intravenous immunoglobulin. Pediatric dermatology 20050101
Comparison of antimicrobial resistance of Acinetobacter baumannii clinical isolates from Shanghai and Hong Kong. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101
[Therapeutical and inflammatory response in rats with secondary peritonitis and topical use of ampicilin/sulbactam]. Acta cirurgica brasileira 20050101
[Clinical experience with the treatment of severe nosocomial infections by inhibitor-protected 3rd generation cephalosporin cefoperazone/sulbactam]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101
Biological treatability of raw and ozonated penicillin formulation effluent. Journal of hazardous materials 20041210
Probable sulbactam/ampicillin-associated prolonged cholestasis. The Annals of pharmacotherapy 20041201
Community-acquired pneumonia due to Pasteurella multocida. Respiratory care 20041201
Synergic in-vitro activity of imipenem and sulbactam against Acinetobacter baumannii. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041201
Pharmacokinetics of a combination preparation of ampicillin and sulbactam in turkeys. American journal of veterinary research 20041201
[Comparison of efficacy between ceftriaxone and cefoperazone plus sulbactam in peri-operative treatment of acute suppurative cholangitis]. Zhonghua yi xue za zhi 20041117
A liquid chromatographic method for simultaneous determination of amoxicillin sodium and sulbactam sodium in a combination formulation. Journal of pharmaceutical and biomedical analysis 20041115
[Comparison of the effects of prophylactic antibiotic therapy and cost-effectiveness between cefazolin (CEZ) and Sulbactam/Ampicillin (SBT/ABPC) in gastric cancer surgery employing clinical pathway]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041101
[Factors participating in development of bleeding varices in portal hypertension. Part I: bacterial infection and comparison of intravenous and peroral antibiotics effects--a randomised study]. Vnitrni lekarstvi 20041101
Microcalorimetric evaluation of the in vitro compatibility of amoxicillin/clavulanic acid and ampicillin/sulbactam with ciprofloxacin. Journal of pharmaceutical and biomedical analysis 20041029
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ESR investigation of gamma irradiated sulbactam sodium. Journal of pharmaceutical and biomedical analysis 20040903
Multidrug-resistant Acinetobacter infections: an emerging challenge to clinicians. The Annals of pharmacotherapy 20040901
Effect of the formulation on the bioequivalence of sultamicillin: tablets and suspension. Arzneimittel-Forschung 20040901
Beta-lactam antibiotic-induced pseudoporphyria. Journal of the American Academy of Dermatology 20040801
The probiotic effect of Saccharomyces boulardii in a pediatric age group. Journal of tropical pediatrics 20040801
Localized linear IgA disease induced by ampicillin/sulbactam. Journal of the American Academy of Dermatology 20040701
Conservative management of clostridial endometritis. American journal of obstetrics and gynecology 20040701
In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria. International journal of antimicrobial agents 20040601
An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae. Journal of chemotherapy (Florence, Italy) 20040601
Susceptibility of the Acinetobacter calcoaceticus-A. baumannii complex to imipenem, meropenem, sulbactam and colistin. International journal of antimicrobial agents 20040501
Post-antibiotic and post-beta-lactamase inhibitor effects of ceftazidime plus sulbactam on extended-spectrum beta-lactamase-producing Gram-negative bacteria. The Journal of antimicrobial chemotherapy 20040401
Meningitis with multidrug-resistant Acinetobacter baumannii treated with ampicillin/sulbactam. The Journal of hospital infection 20040401
Antibiotic prophylaxis in clean neck dissections. The Journal of laryngology and otology 20040301
Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases. Canadian journal of microbiology 20040301
Enterococcus casseliflavus bacteremia. Case report and literature review. The Journal of infection 20040201
In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain. The Journal of antimicrobial chemotherapy 20040201
Intraoperative antibiotic prophylaxis in clean spinal surgery: a retrospective analysis in a consecutive series of 973 cases. Surgical neurology 20040201
Ampicillin + sulbactam vs clindamycin +/- cephalosporin for the treatment of aspiration pneumonia and primary lung abscess. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040201
[A case of tricuspid valve infective endocarditis presenting with multiple nodular shadows in both lungs without known predisposing factors]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20040201
Restricting the use of ampicillin-sulbactam. The Journal of hospital infection 20040201
Treating foot infections in diabetic patients: a randomized, multicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanate. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040101
Use of inhaled ampicillin-sulbactam against multiresistant Acinetobacter baumannii in bronchial secretions of intensive care unit patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040101
Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam. Mini reviews in medicinal chemistry 20040101
Effects of antibiotics and Saccharomyces boulardii on bacterial translocation in burn injury. Surgery today 20040101
Double-disk synergy test positivity in Stenotrophomonas maltophilia clinical strains. Folia microbiologica 20040101
[Antibiotic prophylaxis in laparotomic and laparoscopic cholecystectomy]. Chirurgia italiana 20040101
[Clinical and bacteriological substantiation of the use of cefoperazone/sulbactam in complex therapy of patients with pyo-destructive forms of lower respiratory tract infection (LRTI)]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101
Roseomonas infection associated with a left ventricular assist device. Infection control and hospital epidemiology 20031201
[Surveillance of susceptibility of clinical isolates to cefmetazole between 2000 and 2002]. The Japanese journal of antibiotics 20031201
Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography. Biochemistry 20031125
Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20031101
The susceptibility of non-fermentative Gram-negative bacilli to cefperazone and sulbactam compared with other antibacterial agents. International journal of antimicrobial agents 20031001
Preoperative antimicrobial administration for prevention of postoperative infection in patients with laparoscopic cholecystectomy. Digestive diseases and sciences 20031001
[Synthesis and in vitro antibacterial activities of new 3,5-disubstituted oxazolidinone compounds]. Yao xue xue bao = Acta pharmaceutica Sinica 20031001
Successful treatment of necrotizing fasciitis due to group A streptococcus with impending toxic shock syndrome. Internal medicine (Tokyo, Japan) 20030901
Lung abscess caused by Actinomyces odontolyticus. Internal medicine (Tokyo, Japan) 20030801
The status of drug resistance and ampC gene expression in Enterobacter cloacae. Chinese medical journal 20030801
The effect of antibiotic therapy on intrauterine infection-induced preterm parturition in rabbits. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20030701
Spirocyclopropyl beta-lactams as mechanism-based inhibitors of serine beta-lactamases. Synthesis by rhodium-catalyzed cyclopropanation of 6-diazopenicillanate sulfone. Journal of medicinal chemistry 20030619
Antibiotic therapy in preterm premature rupture of membranes: Are seven days necessary? A preliminary, randomized clinical trial. American journal of obstetrics and gynecology 20030601
Clinical effect of ampicillin with beta-lactamase inhibitor (sulbactam/ampicillin) on community-acquired pneumonia in the elderly. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030601
Considerations in control and treatment of nosocomial infections due to multidrug-resistant Acinetobacter baumannii. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515
In vitro activity of penicillin G/sulbactam compared with penicillin and other antibiotics against common organisms causing ear, nose and throat (ENT) infections. The Journal of antimicrobial chemotherapy 20030501
Nosocomial multi-drug resistant Acinetobacter baumannii bloodstream infection: risk factors and outcome with ampicillin-sulbactam treatment. The Journal of hospital infection 20030501
[Changes of antimicrobial resistance among nonfermenting gram-negative bacilli isolated from intensive care units from 1994 to 2001 in China]. Zhonghua yi xue za zhi 20030310
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HPLC for in-process control in the production of sultamicillin. Journal of pharmaceutical and biomedical analysis 20030226
Severe nosocomial infections with imipenem-resistant Acinetobacter baumannii treated with ampicillin/sulbactam. International journal of antimicrobial agents 20030101
Acute otitis media and facial nerve paralysis in adults. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20030101
[The impact of antibiotic use on hospital-acquired pneumonia: data of etiology tests]. Medicina (Kaunas, Lithuania) 20030101
Urine inhibitory titers against resistant Escherichia coli isolates after oral amoxicillin-sulbactam. Medicina 20030101
[Sulperazone in the treatment of severe infections in patients with cancer]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
[Comparative clinical and epidemiological evaluation of beta-lactam antibiotics in the treatment of intraabdominal infections]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
[Efficacy and safety of cefoperazone/sulbactam in the treatment of children with mucoviscidosis during exacerbation of the bronchopulmonary process]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
Application of micellar electrokinetic chromatography to the determination of sultamicillin in oral pharmaceutical preparations. Journal of chromatography. A 20021206
Efficacy of amoxicillin-sulbactam, given twice-a-day, for the treatment of community-acquired pneumonia: a clinical trial based on a pharmacodynamic model. Journal of chemotherapy (Florence, Italy) 20021201
In vitro investigation of the susceptibility of Acinetobacter baumannii strains isolated from clinical specimens to ampicillin/sulbactam alone and in combination with amikacin. International journal of antimicrobial agents 20021101
Development of an assay for beta-lactam hydrolysis using the pH-dependence of enhanced green fluorescent protein. Analytical biochemistry 20021015
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics. Oral microbiology and immunology 20021001
[The efficacy of prophylactic administration of SBT/ABPC for postoperative infection in neurosurgical operations]. No shinkei geka. Neurological surgery 20021001
Reports of osteopenia/rickets of prematurity are on the increase because of improved survival rates of low birthweight infants. The Journal of emergency medicine 20021001
The effect of high single dose parenteral vitamin A in addition to antibiotic therapy on healing of maxillary sinusitis in experimental acute sinusitis. International journal of pediatric otorhinolaryngology 20020924
Pharmacokinetics of an ampicillin/sulbactam (2:1) combination in rabbits. Journal of veterinary pharmacology and therapeutics 20020801
Antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitis in Argentina. Journal of dairy science 20020801
Surgical antibiotic prophylaxis in a Turkish university hospital. Journal of chemotherapy (Florence, Italy) 20020801
CE versus LC for simultaneous determination of amoxicillin/clavulanic acid and ampicillin/sulbactam in pharmaceutical formulations for injections. Journal of pharmaceutical and biomedical analysis 20020620
Comparison of ampicillin-sulbactam and imipenem-cilastatin for the treatment of acinetobacter ventilator-associated pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020601
Pharmacokinetics of cefoperazone and sulbactam in liver transplant patients. Journal of clinical pharmacology 20020601
[Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999]. The Japanese journal of antibiotics 20020601
[A case of bronchopulmonary actinomycosis diagnosed by transbronchial biopsy of a bronchial polypoid tumor]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20020601
Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence. Infection control and hospital epidemiology 20020501
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections. Oral microbiology and immunology 20020401
Nontraditional dosing of ampicillin-sulbactam for multidrug-resistant Acinetobacter baumannii meningitis. Pharmacotherapy 20020401
The role of cefoperazone-sulbactam for treatment of severe melioidosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020301
Malakoplakia of liver diagnosed by a needle core biopsy: a case report and review of the literature. Archives of pathology & laboratory medicine 20020301
Multiresistant Acinetobacter infections: a role for sulbactam combinations in overcoming an emerging worldwide problem. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20020301
Low dose sultamicillin in acute sinusitis. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20020301
Chronic intrauterine infection and inflammation in the preterm rabbit, despite antibiotic therapy. American journal of obstetrics and gynecology 20020201
In vitro antibiotic release from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) rods. Journal of microencapsulation 20020101
Experience with ampicillin/sulbactam in severe infections. The Journal of international medical research 20020101
[Analysis of prophylactic antibiotics for cesarean section]. Zhonghua fu chan ke za zhi 20020101
[The efficacy of combining antibiotic treatment with topical intranasal steroid administration in the treatment of chronic otitis media with effusion]. Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20020101
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20011201
Parallel analysis of individual and aggregated data on antibiotic exposure and resistance in gram-negative bacilli. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011101
The penetration of cefoperazone and sulbactam into the lumbar intervertebral discs. Journal of spinal disorders 20011001
Epigallocatechin gallate synergy with ampicillin/sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus. The Journal of antimicrobial chemotherapy 20010901
Role of sultamicillin and ampicillin/sulbactam in the treatment of upper and lower bacterial respiratory tract infections. International journal of antimicrobial agents 20010901
In vitro activity of sulperazon against recent isolates of ceftazidime-resistant bacteria. The Medical journal of Malaysia 20010901
Comparison of Neisseria gonorrhoeae isolates from the genital tract and pharynx of two gonorrhea patients. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010901
A randomized, double-blind comparison of ampicillin/sulbactam and ceftriaxone in the prevention of surgical-site infections after neurosurgery. Clinical therapeutics 20010801
Rationale for treating community-acquired lower respiratory tract infections with amoxicillin/sulbactam combination through pharmacodynamic analysis in the setting of aminopenicillin-resistant organisms. Journal of chemotherapy (Florence, Italy) 20010801
Randomized, double-blind, controlled study of cefoperazone-sulbactam plus cotrimoxazole versus ceftazidime plus cotrimoxazole for the treatment of severe melioidosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010701
Index of suspicion. Case 2. Diagnosis: Ludwig angina. Pediatrics in review 20010701
Pharmacokinetics of antibiotic prophylaxis in major orthopedic surgery and blood-saving techniques. Orthopedics 20010701
Piperacillin, beta-lactam inhibitor plus gentamicin as empirical therapy of a sequential regimen in febrile neutropenia of pediatric cancer patients. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010701
Penicillins and beta-lactamase inhibitor combinations. Journal of the American Veterinary Medical Association 20010615
An anaphylactic reaction possibly associated with an intraoperative coronary artery spasm during general anesthesia. Journal of clinical anesthesia 20010501
[Escherichia coli eradication from the blader urine by amoxicillin-sulbactam. Intrinsic activity of the inhibitor]. Enfermedades infecciosas y microbiologia clinica 20010501
Sulbactam efficacy in experimental models caused by susceptible and intermediate Acinetobacter baumannii strains. The Journal of antimicrobial chemotherapy 20010401
[Fundamental and clinical studies on beta-lactamase inhibitors]. Nihon rinsho. Japanese journal of clinical medicine 20010401
[Clinical analysis of neutropenic fever associated with hematological disorders]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010301
[The inducibility of Amp C enzyme of Enterobacter cloacae and its susceptibility to enzyme inhibitor]. Zhonghua yi xue za zhi 20010225
The in vitro activity of sulbactam combined with third generation cephalosporins against third generation cephalosporin-resistant bacteria. International journal of antimicrobial agents 20010201
Incidence of beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of orofacial odontogenic infections. Oral microbiology and immunology 20010201
Epidemiology, resistance, and outcomes of Acinetobacter baumannii bacteremia treated with imipenem-cilastatin or ampicillin-sulbactam. Pharmacotherapy 20010201
In vivo application of biodegradable controlled antibiotic release systems for the treatment of implant-related osteomyelitis. Biomaterials 20010101
Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial. Annals of surgery 20010101
Effect of granulocyte-macrophage colony-stimulating factor on treatment of acute osteomyelitis. An experimental investigation in rats. Archives of orthopaedic and trauma surgery 20010101
Antibiotic susceptibility, serum response and surface properties of Klebsiella species. Microbios 20010101
Sepsis and multiple brain abscesses caused by Salmonella paratyphi B in an infant: successful treatment with sulbactam-ampicillin and surgical drainage. The Turkish journal of pediatrics 20010101
Group F streptococcal bacteremia complicating a Bartholin's abscess. Infectious diseases in obstetrics and gynecology 20010101
Biodegradable polyhydroxyalkanoate implants for osteomyelitis therapy: in vitro antibiotic release. Journal of biomaterials science. Polymer edition 20010101
In vitro effect of ampicillin/sulbactam on Acinetobacter species. Microbios 20010101
Use of ampicillin/sulbactam and sultamicillin in pediatric infections: a re-evaluation. The Journal of international medical research 20010101
Effect of cefaperazone/sulbactam and ampicillin/sulbactam on the in vitro activity of human erythrocyte glucose-6-phosphate dehydrogenase. Journal of basic and clinical physiology and pharmacology 20010101
An unusual form of Actinomycosis of the mandible with a resultant gross sequester in a 4-year-old child: a case report. The Journal of clinical pediatric dentistry 20010101
Bactericidal action of ampicillin/sulbactam against intracellular mycobacteria. International journal of antimicrobial agents 19991001
Postantibiotic effect of ampicillin/sulbactam against mycobacteria. Microbios 19990101
Positive direct antiglobulin tests and haemolytic anaemia following therapy with beta-lactamase inhibitor containing drugs may be associated with nonimmunologic adsorption of protein onto red blood cells. British journal of haematology 19980301
Myocardial injury caused by an anaphylactic reaction to ampicillin/sulbactam in a patient with normal coronary arteries. Texas Heart Institute journal 19980101
Pharmacokinetics of mezlocillin and sulbactam under continuous veno-venous hemodialysis (CVVHD) in intensive care patients with acute renal failure. European journal of clinical pharmacology 19970101
The in vitro activity of beta-lactamase inhibitors in combination with cephalosporins against M. tuberculosis. Proceedings of the National Science Council, Republic of China. Part B, Life sciences 19950401
Ampicillin, sulbactam, and rifampin combination treatment of experimental methicillin-resistant Staphylococcus aureus endocarditis in rabbits. The Journal of infectious diseases 19950401
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