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69-81-8

69-81-8 | 2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1H-indol-5(6H)-ylidene)hydrazinecarboxamide

CAS No: 69-81-8 Catalog No: AG003ETW MDL No:MFCD00059705

Product Description

Catalog Number:
AG003ETW
Chemical Name:
2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1H-indol-5(6H)-ylidene)hydrazinecarboxamide
CAS Number:
69-81-8
Molecular Formula:
C10H12N4O3
Molecular Weight:
236.2273
MDL Number:
MFCD00059705
IUPAC Name:
(3,6-dihydroxy-1-methyl-2,3-dihydroindol-5-yl)iminourea
InChI:
InChI=1S/C10H12N4O3/c1-14-4-9(16)5-2-6(12-13-10(11)17)8(15)3-7(5)14/h2-3,9,15-16H,4H2,1H3,(H2,11,17)
InChI Key:
SSCSSDNTQJGTJT-UHFFFAOYSA-N
SMILES:
NC(=O)N/N=C\1/C=C2C(O)CN(C2=CC1=O)C
EC Number:
200-717-0
NSC Number:
73742

Properties

Complexity:
336  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
236.091g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
236.231g/mol
Monoisotopic Mass:
236.091g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
112A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
0

Literature

Title Journal
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Prospective multicenter study of visual outcomes following three different treatments for macular edema associated with branch retinal vein occlusion: a study by the Japanese BRVO study group. Japanese journal of ophthalmology 20120501
Risk of deep venous thrombosis in drain clamping with tranexamic acid and carbazochrome sodium sulfonate hydrate in total knee arthroplasty. The Journal of arthroplasty 20120101
Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro. Biochemistry 20101214
Development and validation of a robust LC-MS-MS with atmospheric pressure chemical ionization for quantitation of carbazochrome sodium sulfonate in human plasma: application to a pharmacokinetic study. Biomedical chromatography : BMC 20100901
Effect of furosemide and furosemide-carbazochrome combination on exercise-induced pulmonary hemorrhage in Standardbred racehorses. The Canadian veterinary journal = La revue veterinaire canadienne 20090801
Short-term delayed-release microcapsules spraycoated with acrylic terpolymers. International journal of pharmaceutics 20060113
Dengue fever. Clinical evidence 20050601
Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells. Naunyn-Schmiedeberg's archives of pharmacology 20030901
Combination therapy of DDAVP and conjugated estrogens for a recurrent large subcutaneous hematoma in Ehlers-Danlos syndrome. American journal of hematology 20030101
[A 50-year history of new drugs in Japan-the development and trends of hemostatics and antithrombotic drugs]. Yakushigaku zasshi 20030101
[Case of pulmonary actinomycosis refractory to therapy]. The Japanese journal of antibiotics 20021201
Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. European journal of pharmacology 20020823
Parenteral troxerutin and carbazochrome combination in the treatment of post-hemorrhoidectomy status: a randomized, double-blind, placebo-controlled, phase IV study. Current medical research and opinion 20010101
Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids. European review for medical and pharmacological sciences 20000101

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