200,000+ products from a single source!
sales@angenechem.com
Home > Quinoline > 686722-53-2
686722-53-2 | 8-Quinolinol, 5-[[4-(2-propynyl)-1-piperazinyl]methyl]-
CAS No: 686722-53-2 Catalog No: AG006I1V MDL No:
Product Description
Catalog Number:
AG006I1V
Chemical Name:
8-Quinolinol, 5-[[4-(2-propynyl)-1-piperazinyl]methyl]-
CAS Number:
686722-53-2
Molecular Formula:
C17H19N3O
Molecular Weight:
281.3523
IUPAC Name:
5-[(4-prop-2-ynylpiperazin-1-yl)methyl]quinolin-8-ol
InChI:
InChI=1S/C17H19N3O/c1-2-8-19-9-11-20(12-10-19)13-14-5-6-16(21)17-15(14)4-3-7-18-17/h1,3-7,21H,8-13H2
InChI Key:
JWUOZHTYFQHGAB-UHFFFAOYSA-N
SMILES:
C#CCN1CCN(CC1)Cc1ccc(c2c1cccn2)O
UNII:
2JH24KL4ZG
Properties
Complexity:
383
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
281.153g/mol
Formal Charge:
0
Heavy Atom Count:
21
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
281.359g/mol
Monoisotopic Mass:
281.153g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
39.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8
Literature
| Title | Journal |
|---|---|
| From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20120101 |
| Selective acetylcholinesterase inhibitor activated by acetylcholinesterase releases an active chelator with neurorescuing and anti-amyloid activities. | ACS chemical neuroscience 20101117 |
| The novel multifunctional, iron-chelating drugs M30 and HLA20 protect pancreatic beta-cell lines from oxidative stress damage. | The Journal of pharmacology and experimental therapeutics 20100601 |
| Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101 |
| Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501 |
| Multifunctional neuroprotective drugs targeting monoamine oxidase inhibition, iron chelation, adenosine receptors, and cholinergic and glutamatergic action for neurodegenerative diseases. | Expert opinion on investigational drugs 20060801 |
| Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition. | Journal of neurochemistry 20051001 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.