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68291-97-4 | 1,2-Benzisoxazole-3-methanesulfonamide
CAS No: 68291-97-4 Catalog No: AG00IBTF MDL No:MFCD00865316
Product Description
Catalog Number:
AG00IBTF
Chemical Name:
1,2-Benzisoxazole-3-methanesulfonamide
CAS Number:
68291-97-4
Molecular Formula:
C8H8N2O3S
Molecular Weight:
212.2257
MDL Number:
MFCD00865316
IUPAC Name:
1,2-benzoxazol-3-ylmethanesulfonamide
InChI:
InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
InChI Key:
UBQNRHZMVUUOMG-UHFFFAOYSA-N
SMILES:
NS(=O)(=O)Cc1noc2c1cccc2
EC Number:
614-395-8
UNII:
459384H98V
Properties
Complexity:
298
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
212.026g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
212.223g/mol
Monoisotopic Mass:
212.026g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
94.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2
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| Treating Lennox-Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide. | Neuropsychiatric disease and treatment 20100101 |
| Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms. | Neuropsychiatric disease and treatment 20100101 |
| Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease. | International journal of molecular sciences 20100101 |
| Adjunctive therapy for the treatment of primary generalized tonic-clonic seizures: focus on once-daily lamotrigine. | Drug design, development and therapy 20100101 |
| Advances in epilepsy: new perspectives on new-onset epilepsy, comorbidities, and pharmacotherapy. | F1000 medicine reports 20100101 |
| Familial vulnerability to an unusual cognitive adverse effect of topiramate: Discussion of mechanisms. | Indian journal of psychiatry 20100101 |
| Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study. | PloS one 20100101 |
| Determination and Validation of Zonisamide and its Four Related Substances by HPLC and UV-Spectrophotometry. | Indian journal of pharmaceutical sciences 20100101 |
| Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients. | Nutrition journal 20100101 |
| Tackling obesity: new therapeutic agents for assisted weight loss. | Diabetes, metabolic syndrome and obesity : targets and therapy 20100101 |
| JSNT-Guidelines for the Management of Severe Head Injury (Abridged edition). | Asian journal of neurosurgery 20100101 |
| [Antiepileptic drugs for the prevention of pediatric migraine]. | Revue neurologique 20091201 |
| Requirements for generic anti-epileptic medicines: a regulatory perspective. | Journal of neurology 20091201 |
| Zonisamide in West syndrome: an open label study. | Epileptic disorders : international epilepsy journal with videotape 20091201 |
| Resolution of pregabalin and mirtazapine associated restless legs syndrome by bupropion in a patient with major depressive disorder. | Psychiatry investigation 20091201 |
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| Zonisamide Combined with Cognitive Behavioral Therapy in Binge Eating Disorder: A One-year Follow-up Study. | Psychiatry (Edgmont (Pa. : Township)) 20091101 |
| Anticonvulsant drugs for pediatric migraine prevention: an evidence-based review. | European journal of pain (London, England) 20091001 |
| A novel anti-Parkinsonian agent, zonisamide, attenuates MPTP-induced neurotoxicity in mice. | Journal of molecular neuroscience : MN 20090901 |
| Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathway. | Neuropharmacology 20090901 |
| The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent? | Epilepsia 20090901 |
| Efficacy and tolerability of zonisamide as add-on in brain tumor-related epilepsy: preliminary report. | Acta neurologica Scandinavica 20090901 |
| The need for broad spectrum and safe anti-epileptic drugs in childhood epilepsy. | Acta neurologica Belgica 20090901 |
| A review of the use of zonisamide in Parkinson's disease. | Therapeutic advances in neurological disorders 20090901 |
| The influence of concurrent anticonvulsants on the efficacy of the ketogenic diet. | Epilepsia 20090801 |
| Zonisamide: in Parkinson's disease. | CNS drugs 20090801 |
| Absence seizures: a review of recent reports with new concepts. | Epilepsy & behavior : E&B 20090801 |
| A case of Rasmussen encephalitis treated with rituximab. | Nature reviews. Neurology 20090801 |
| Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation. | Neurophysiologie clinique = Clinical neurophysiology 20090801 |
| Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study. | Biomedical chromatography : BMC 20090701 |
| [The role of the neuromodulators in the preventive treatment of migraine]. | Revista de neurologia 20090701 |
| Stability of zonisamide in extemporaneously compounded oral suspensions. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090615 |
| Bioequivalence of zonisamide orally dispersible tablet and immediate-release capsule formulations: results from two open-label, randomized-sequence, single-dose, two-period, two-treatment crossover studies in healthy male volunteers. | Clinical therapeutics 20090601 |
| [Drug-induced hypersensitivity syndrome and HHV-6 reactivation]. | Uirusu 20090601 |
| Antiepileptic drug monotherapy: the initial approach in epilepsy management. | Current neuropharmacology 20090601 |
| Transitional polytherapy: tricks of the trade for monotherapy to monotherapy AED conversions. | Current neuropharmacology 20090601 |
| Truly 'rational' polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects. | Current neuropharmacology 20090601 |
| Minimizing AED adverse effects: improving quality of life in the interictal state in epilepsy care. | Current neuropharmacology 20090601 |
| Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. | Journal of medicinal chemistry 20090514 |
| The seizuring cat. Diagnostic work-up and therapy. | Journal of feline medicine and surgery 20090501 |
| Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP. | Journal of pharmacological sciences 20090501 |
| Possible mechanism for zonisamide-induced hyperammonemia in a child with citrullinemia type 1. | Indian journal of medical sciences 20090501 |
| Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors. | Neuroscience letters 20090417 |
| Propriospinal myoclonus revisited: Clinical, neurophysiologic, and neuroradiologic findings. | Neurology 20090414 |
| QSAR studies for the inhibition of the transmembrane carbonic anhydrase isozyme XIV with sulfonamides using PRECLAV software. | Journal of enzyme inhibition and medicinal chemistry 20090401 |
| The impact of zonisamide on weight. A clinical study in 103 patients with epilepsy. | Acta neurologica Scandinavica 20090401 |
| [New antiepileptic drugs]. | La Revue de medecine interne 20090401 |
| Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. | Epilepsy research 20090401 |
| Effects of antiepileptics on lateral geniculate nucleus-kindled seizures in rats. | Journal of pharmacological sciences 20090401 |
| [Pharmacologic treatment of Parkinson disease]. | Brain and nerve = Shinkei kenkyu no shinpo 20090401 |
| Case-control analysis of ambulance, emergency room, or inpatient hospital events for epilepsy and antiepileptic drug formulation changes. | Epilepsia 20090301 |
| Can antiepileptic drugs unmask a susceptibility to psychiatric disorders? | Nature clinical practice. Neurology 20090301 |
| Efficacy and tolerability of zonisamide in idiopathic generalized epilepsy. | Epileptic disorders : international epilepsy journal with videotape 20090301 |
| Treatment of epilepsy in severely disabled children with bilateral brain malformations. | Journal of the neurological sciences 20090215 |
| Zonisamide for essential tremor: an evaluator-blinded study. | Movement disorders : official journal of the Movement Disorder Society 20090215 |
| Effect of antiepileptic drug polytherapy on urinary pH in children and young adults. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20090201 |
| Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels. | Neuropharmacology 20090201 |
| Dose adjustment of phenytoin for comedication in Japanese patients with epilepsy. | Therapeutic drug monitoring 20090201 |
| Zonisamide in children and young adults with refractory epilepsy: an open label, multicenter Italian study. | Epilepsy research 20090201 |
| Zonisamide block of cloned human T-type voltage-gated calcium channels. | Epilepsy research 20090201 |
| Epilepsy. | BMJ clinical evidence 20090128 |
| Open-label, long-term safety study of zonisamide administered to children and adolescents with epilepsy. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20090101 |
| Effects of zonisamide on c-Fos expression under conditions of tacrine-induced tremulous jaw movements in rats: a potential mechanism underlying its anti-parkinsonian tremor effect. | Parkinsonism & related disorders 20090101 |
| Zonisamide for migraine prophylaxis in patients refractory to topiramate. | Clinical neuropharmacology 20090101 |
| Patient-reported cognitive side effects of antiepileptic drugs: predictors and comparison of all commonly used antiepileptic drugs. | Epilepsy & behavior : E&B 20090101 |
| Role of antiepileptic drugs in the management of eating disorders. | CNS drugs 20090101 |
| [Role of monotherapy with new antiepileptic drugs in the treatment of childhood epilepsy]. | Medicina 20090101 |
| Understanding patients' perspective in the use of generic antiepileptic drugs: compelling lessons for physicians to improve physician/patient communication. | BMC neurology 20090101 |
| Managing epilepsy in women of childbearing age. | Drug safety 20090101 |
| Long-term safety and effectiveness of zonisamide in the treatment of epilepsy: a review of the literature. | Neuropsychiatric disease and treatment 20090101 |
| Current trends in the treatment of infantile spasms. | Neuropsychiatric disease and treatment 20090101 |
| The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers. | The American journal of drug and alcohol abuse 20090101 |
| Idiopathic hemifacial spasm responsive to zonisamide: a case report. | Clinical neuropharmacology 20090101 |
| Treatment of obese patients with binge eating disorder using topiramate: a review. | Neuropsychiatric disease and treatment 20090101 |
| Substitution of anticonvulsant drugs. | Therapeutics and clinical risk management 20090101 |
| Lacosamide as treatment for partial epilepsy: mechanisms of action, pharmacology, effects, and safety. | Therapeutics and clinical risk management 20090101 |
| [Juvenile myoclonic epilepsy with recurrent myoclonic status: efficacy of valproate]. | Therapie 20090101 |
| Update on the management of Lennox-Gastaut syndrome with a focus on rufinamide. | Neuropsychiatric disease and treatment 20090101 |
| Status epilepticus. | Annals of Indian Academy of Neurology 20090101 |
| HPLC method for simultaneous determination of impurities and degradation products in zonisamide. | Indian journal of pharmaceutical sciences 20090101 |
| Topiramate induced agranulocytosis. | BMJ case reports 20090101 |
| [Zonisamide as add-on treatment for focal epilepsies. An outcome analysis of 74 patients]. | Der Nervenarzt 20081201 |
| Predicting possible zonisamide hypersensitivity syndrome. | Experimental dermatology 20081201 |
| Disposition and safety of zonisamide after intravenous and oral single dose and oral multiple dosing in normal hound dogs. | Journal of veterinary pharmacology and therapeutics 20081201 |
| Debate: Does genetic information in humans help us treat patients? PRO--genetic information in humans helps us treat patients. CON--genetic information does not help at all. | Epilepsia 20081201 |
| Treatment of Lennox-Gastaut syndrome: overview and recent findings. | Neuropsychiatric disease and treatment 20081201 |
| Pregabalin for the management of partial epilepsy. | Neuropsychiatric disease and treatment 20081201 |
| Cross-sensitivity of skin rashes with antiepileptic drug use. | Neurology 20081104 |
| Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081101 |
| Management of and prophylaxis against status epilepticus in children with severe myoclonic epilepsy in infancy (SMEI; Dravet syndrome)--a nationwide questionnaire survey in Japan. | Brain & development 20081101 |
| Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series. | European eating disorders review : the journal of the Eating Disorders Association 20081101 |
| Effects of zonisamide on isolated head tremor. | European journal of neurology 20081101 |
| Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition. | Epilepsy research 20081101 |
| [Antiepileptic drugs in pediatric migraine]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20081101 |
| [Preventive treatment of chronic migraine with zonisamide: a study in patients who are refractory or intolerant to topiramate]. | Revista de neurologia 20081101 |
| [Therapy of Parkinson's disease--up to date]. | Rinsho shinkeigaku = Clinical neurology 20081101 |
| New antiepileptic drugs in pediatric epilepsy. | Brain & development 20081001 |
| Treatment of seizures in a patient with Batten's disease. | The Nurse practitioner 20081001 |
| Pharmacotherapeutics of epilepsy: use of lamotrigine and expectations for lamotrigine extended release. | Therapeutics and clinical risk management 20081001 |
| Optimizing prophylactic treatment of migraine: Subtypes and patient matching. | Therapeutics and clinical risk management 20081001 |
| Therapeutic role of zonisamide in neuropsychiatric disorders. | Mini reviews in medicinal chemistry 20080901 |
| Cognitive effects of antiepileptic drugs. | Journal of clinical neurology (Seoul, Korea) 20080901 |
| Generic substitution in the treatment of epilepsy: case evidence of breakthrough seizures. | Neurology 20080812 |
| Pharmacokinetics and toxicity of zonisamide in cats. | Journal of feline medicine and surgery 20080801 |
| Long-term safety and efficacy of zonisamide in patients with refractory partial-onset epilepsy. | Acta neurologica Scandinavica 20080801 |
| Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. | Bioorganic & medicinal chemistry 20080801 |
| Population estimation regarding the effects of cytochrome P450 2C19 and 3A5 polymorphisms on zonisamide clearance. | Therapeutic drug monitoring 20080801 |
| Approaches to treatment of type 2 diabetes. | Diabetes care 20080801 |
| Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy. | PLoS medicine 20080801 |
| Central nervous system adverse effects of new antiepileptic drugs. A meta-analysis of placebo-controlled studies. | Seizure 20080701 |
| Molecular analysis and anticonvulsant therapy in two patients with glucose transporter 1 deficiency syndrome: a successful use of zonisamide for controlling the seizures. | Epilepsy research 20080701 |
| Zonisamide concentrations during pregnancy. | The Annals of pharmacotherapy 20080701 |
| Zonisamide decreases cortical excitability in patients with idiopathic generalized epilepsy. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20080601 |
| Does drug-induced hypersensitivity syndrome elicit bullous pemphigoid? | Allergology international : official journal of the Japanese Society of Allergology 20080601 |
| Pharmacokinetics of zonisamide and drug interaction with phenobarbital in dogs. | Journal of veterinary pharmacology and therapeutics 20080601 |
| Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives. | Bioorganic & medicinal chemistry 20080601 |
| High-speed simultaneous determination of nine antiepileptic drugs using liquid chromatography-mass spectrometry. | Therapeutic drug monitoring 20080601 |
| Secondary osteoporosis in long-term bedridden patients with cerebral palsy. | Pediatrics international : official journal of the Japan Pediatric Society 20080601 |
| Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity. | Expert opinion on emerging drugs 20080601 |
| Drug monitoring and toxicology: a simple procedure for the monitoring of felbamate by HPLC-UV detection. | Journal of analytical toxicology 20080601 |
| Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. | Journal of pharmacological sciences 20080601 |
| Acute and long-term treatment of mania. | Dialogues in clinical neuroscience 20080601 |
| Management of migraine in adolescents. | Neuropsychiatric disease and treatment 20080601 |
| Levetiracetam in the treatment of epilepsy. | Neuropsychiatric disease and treatment 20080601 |
| Adjunctive zonisamide for weight loss in euthymic bipolar disorder patients: a pilot study. | Journal of psychiatric research 20080501 |
| Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition. | Epilepsy research 20080501 |
| Clinical efficacy of zonisamide in Lennox-Gastaut syndrome: Korean multicentric experience. | Brain & development 20080401 |
| Neuromodulators for migraine prevention. | Headache 20080401 |
| Carbonic anhydrase inhibition. Insight into the characteristics of zonisamide, topiramate, and the sulfamide cognate of topiramate. | Journal of enzyme inhibition and medicinal chemistry 20080401 |
| Zonisamide: review of pharmacology, clinical efficacy, tolerability, and safety. | Expert opinion on drug metabolism & toxicology 20080401 |
| Translocation-positive acute myeloid leukemia associated with valproic acid therapy. | Pediatric blood & cancer 20080301 |
| Zonisamide for the treatment of myoclonic seizures in progressive myoclonic epilepsy: an open-label study. | Epileptic disorders : international epilepsy journal with videotape 20080301 |
| Pregnancy, epilepsy, and anticonvulsants. | Dialogues in clinical neuroscience 20080301 |
| The effectiveness of anticonvulsants in psychiatric disorders. | Dialogues in clinical neuroscience 20080301 |
| GABA(A) receptors in normal development and seizures: friends or foes? | Current neuropharmacology 20080301 |
| Toxic epidermal necrolysis due to zonisamide associated with reactivation of human herpesvirus 6. | Archives of dermatology 20080201 |
| [Zonisamide in refractory essential tremor]. | Revista de neurologia 20080201 |
| Monotherapy for partial epilepsy: focus on levetiracetam. | Neuropsychiatric disease and treatment 20080201 |
| Long-term use of zonisamide in refractory childhood-onset epilepsy. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080101 |
| Is adjunctive open-label zonisamide effective for bipolar disorder? | Journal of affective disorders 20080101 |
| Effects of zonisamide on experimental tremors in rats. | Parkinsonism & related disorders 20080101 |
| Long-term cognitive and mood effects of zonisamide monotherapy in epilepsy patients. | Epilepsy & behavior : E&B 20080101 |
| Preventing effects of a novel anti-parkinsonian agent zonisamide on dopamine quinone formation. | Neuroscience research 20080101 |
| Emerging concepts in the medical and surgical treatment of obesity. | Frontiers of hormone research 20080101 |
| Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs? | Current pharmaceutical design 20080101 |
| Xerosis and pityriasis alba-like changes associated with zonisamide. | Indian journal of dermatology, venereology and leprology 20080101 |
| Use of second-generation antiepileptic drugs in the pediatric population. | Paediatric drugs 20080101 |
| CNS adverse events associated with antiepileptic drugs. | CNS drugs 20080101 |
| Antiepileptic drug therapy in pregnancy II: fetal and neonatal exposure. | International review of neurobiology 20080101 |
| Seizure control in patients with epilepsy: the physician vs. medication factors. | BMC health services research 20080101 |
| Abstracts of papers presented at the 2008 pittsburgh conference. | Journal of automated methods & management in chemistry 20080101 |
| High-performance liquid chromatographic method for determination of phenytoin in rabbits receiving sildenafil. | Analytical chemistry insights 20080101 |
| Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. | Bioorganic & medicinal chemistry 20071201 |
| [Anticonvulsant treatment with zonisamide added to topiramate. A preliminary treatment analysis in 19 patients]. | Der Nervenarzt 20071201 |
| The new antiepileptic drugs. | Archives of disease in childhood. Education and practice edition 20071201 |
| Treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy. | Neuropsychiatric disease and treatment 20071201 |
| Long-term efficacy and safety of zonisamide monotherapy in epilepsy patients. | Journal of clinical neurology (Seoul, Korea) 20071201 |
| Association of human herpesvirus 6 reactivation with the flaring and severity of drug-induced hypersensitivity syndrome. | The British journal of dermatology 20071101 |
| Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome. | Pediatric neurology 20071101 |
| Zonisamide in patients with essential tremor and Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20071031 |
| Timed pentylenetetrazol infusion test: a comparative analysis with s.c.PTZ and MES models of anticonvulsant screening in mice. | Seizure 20071001 |
| A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial. | Health technology assessment (Winchester, England) 20071001 |
| Assessment of antiepileptic drugs as substrates for canine P-glycoprotein. | American journal of veterinary research 20071001 |
| [Zonisamide and neuropathic pain]. | Revista de neurologia 20071001 |
| Neuroleptic malignant syndrome-like state in an epileptic patient with organic brain comorbidity treated with zonisamide and carbamazepine. | Epilepsia 20071001 |
| Drug monitoring: simultaneous analysis of lamotrigine, oxcarbazepine, 10-hydroxycarbazepine, and zonisamide by HPLC-UV and a rapid GC method using a nitrogen-phosphorus detector for levetiracetam. | Journal of chromatographic science 20071001 |
| Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915 |
| Zonisamide for the treatment of Parkinson's disease. | Expert review of neurotherapeutics 20070901 |
| Old and new antiepileptic drugs for the treatment of idiopathic generalized epilepsies. | Current clinical pharmacology 20070901 |
| [Neuromuscular disorders caused by adverse effects of antiepileptics]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810 |
| A case of Moebius syndrome presenting with congenital bilateral vocal cord paralysis. | European journal of pediatrics 20070801 |
| Zonisamide and renal calculi in patients with epilepsy: how big an issue? | Current medical research and opinion 20070801 |
| Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons. | Epilepsy research 20070801 |
| The supraspinally mediated analgesic effects of zonisamide in mice after peripheral nerve injury are independent of the descending monoaminergic system. | Journal of pharmacological sciences 20070801 |
| Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study. | The Journal of clinical psychiatry 20070801 |
| Restless legs syndrome induced by zonisamide. | Movement disorders : official journal of the Movement Disorder Society 20070730 |
| A case of Kabuki syndrome presenting West syndrome. | Brain & development 20070701 |
| Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs. | Epilepsia 20070701 |
| Pediatric migraine: pharmacologic agents for prophylaxis. | The Annals of pharmacotherapy 20070701 |
| Efficacy and safety of adjunctive zonisamide therapy for refractory partial seizures. | Epilepsy research 20070701 |
| Use of the newer antiepileptic drugs in pediatric epilepsies. | Current treatment options in neurology 20070701 |
| Zonisamide in Parkinson's disease. | Current neurology and neuroscience reports 20070701 |
| Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA. | Bioorganic & medicinal chemistry 20070615 |
| Comparative retention rates and long-term tolerability of new antiepileptic drugs. | Seizure 20070601 |
| Adjunctive zonisamide for treatment refractory anxiety. | International journal of clinical practice 20070601 |
| Zonisamide: new drug. No advantage in refractory partial epilepsy. | Prescrire international 20070601 |
| Comparison and predictors of rash associated with 15 antiepileptic drugs. | Neurology 20070515 |
| A novel high sensitivity HPLC assay for topiramate, using 4-chloro-7-nitrobenzofurazan as pre-column fluorescence derivatizing agent. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
| Sclerodermoid graft-versus-host disease-like lesions occurring after drug-induced hypersensitivity syndrome. | The British journal of dermatology 20070501 |
| Zonisamide decreases ethanol intake in rats and mice. | Pharmacology, biochemistry, and behavior 20070501 |
| A new look at the second-generation antiepileptic drugs: a decade of experience. | The neurologist 20070501 |
| Current treatment of West syndrome in Japan. | Journal of child neurology 20070501 |
| Activation by zonisamide, a newer antiepileptic drug, of large-conductance calcium-activated potassium channel in differentiated hippocampal neuron-derived H19-7 cells. | The Journal of pharmacology and experimental therapeutics 20070401 |
| Psychosis following initiation of zonisamide. | The American journal of psychiatry 20070401 |
| Zonisamide as treatment for seizures. | The Nurse practitioner 20070401 |
| Recommendations for the management of migraine in paediatric patients. | Expert opinion on pharmacotherapy 20070401 |
| Potential efficacy of zonisamide in refractory juvenile myoclonic epilepsy: retrospective evidence from an Irish compassionate-use case series. | Irish medical journal 20070401 |
| Kidney stones and the ketogenic diet: risk factors and prevention. | Journal of child neurology 20070401 |
| Interactions between zonisamide and conventional antiepileptic drugs in the mouse maximal electroshock test model. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070301 |
| Simultaneous determination of lamotrigine, zonisamide, and carbamazepine in human plasma by high-performance liquid chromatography. | Biomedical chromatography : BMC 20070301 |
| Pharmacokinetics and drug interactions with zonisamide. | Epilepsia 20070301 |
| Prospective study of zonisamide therapy for refractory idiopathic epilepsy in dogs. | The Journal of small animal practice 20070301 |
| Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy. | Epilepsy & behavior : E&B 20070201 |
| Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese. | Therapeutic drug monitoring 20070201 |
| [Newer antiepileptic drugs]. | No to shinkei = Brain and nerve 20070201 |
| [Newer antiepileptic drugs]. | Brain and nerve = Shinkei kenkyu no shinpo 20070201 |
| A double-blind placebo-controlled trial of zonisamide (zonegran) in the treatment of essential tremor. | Movement disorders : official journal of the Movement Disorder Society 20070115 |
| Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study. | Neurology 20070102 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Novel anticonvulsant drugs. | Pharmacology & therapeutics 20070101 |
| Zonisamide or levetiracetam for adults with cyclic vomiting syndrome: a case series. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070101 |
| Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII). | Epilepsy research 20070101 |
| Zonisamide for bipolar depression. | Expert opinion on pharmacotherapy 20070101 |
| Targets for antiepileptic drugs in the synapse. | Medical science monitor : international medical journal of experimental and clinical research 20070101 |
| Discovery of antiepileptic drugs. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101 |
| Use of antiepileptic drugs for nonepileptic conditions: psychiatric disorders and chronic pain. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101 |
| [Valproate sodium and zonisamide associated interstitial pneumonitis in an infant]. | No to hattatsu = Brain and development 20070101 |
| Suicidality and antiepileptic drugs: is there a link? | Drug safety 20070101 |
| Erratum to 'Safety of zonisamide therapy: prospective follow-up survey.'. | Seizure 20070101 |
| Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium. | Clinical pharmacokinetics 20070101 |
| Antiobesity carbonic anhydrase inhibitors. | Current topics in medicinal chemistry 20070101 |
| Novel base catalysed rearrangement of sultone oximes to 1,2-benzisoxazole-3-methane sulfonate derivatives. | Beilstein journal of organic chemistry 20070101 |
| Negative effects of antiepileptic drugs on mood in patients with epilepsy. | Drug safety 20070101 |
| Clinical pharmacology and mechanism of action of zonisamide. | Clinical neuropharmacology 20070101 |
| Weight issues for people with epilepsy--a review. | Epilepsia 20070101 |
| Zonisamide for essential tremor. | Clinical neuropharmacology 20070101 |
| Rimonabant: the evidence for its use in the treatment of obesity and the metabolic syndrome. | Core evidence 20070101 |
| Optimizing therapy of seizures in women who use oral contraceptives. | Neurology 20061226 |
| Effects of some antiepileptics on septal-kindled seizures in rats. | Epilepsy research 20061201 |
| Rapid identification of P-glycoprotein substrates and inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20061201 |
| Restoration of bile ducts in drug-induced vanishing bile duct syndrome due to zonisamide. | The American journal of surgical pathology 20061201 |
| Comorbidity of eating disorders with bipolar disorder and treatment implications. | Bipolar disorders 20061201 |
| New findings from the Bipolar Collaborative Network: clinical implications for therapeutics. | Current psychiatry reports 20061201 |
| Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. | The Journal of clinical psychiatry 20061201 |
| Treatments for late-life bipolar disorder. | The American journal of geriatric pharmacotherapy 20061201 |
| Treatment of infantile spasms. | Current treatment options in neurology 20061101 |
| A long-term follow-up of zonisamide monotherapy. | Epilepsia 20061101 |
| [New medications; zonisamide]. | Nederlands tijdschrift voor geneeskunde 20061021 |
| Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas. | British journal of cancer 20061009 |
| Zonisamide eradicated paroxysmal headache with EEG abnormalities triggered by hypertensive encephalopathy due to purpura nephritic syndrome. | Brain & development 20061001 |
| Zonisamide for migraine prophylaxis in refractory patients. | Cephalalgia : an international journal of headache 20061001 |
| Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies? | Acta neurologica Scandinavica 20060901 |
| Zonisamide for the treatment of epilepsy. | Expert review of neurotherapeutics 20060901 |
| Zonisamide - a review of experience and use in partial seizures. | Neuropsychiatric disease and treatment 20060901 |
| Prophylaxis of migraine. | Neuropsychiatric disease and treatment 20060901 |
| Topiramate monotherapy in infantile spasm. | Yonsei medical journal 20060831 |
| An open prospective study of zonisamide in acute bipolar depression. | Journal of clinical psychopharmacology 20060801 |
| Zonisamide-induced mania in an essential tremor patient. | Journal of clinical psychopharmacology 20060801 |
| Development of dosage design of hepatic metabolizing drugs using serum albumin level in chronic hepatic failure. | Biological & pharmaceutical bulletin 20060801 |
| Effects of divalproex and atypical antipsychotic drugs on dopamine and acetylcholine efflux in rat hippocampus and prefrontal cortex. | Brain research 20060712 |
| Determination of zonisamide by a coated monolithic column. | Journal of chromatography. A 20060616 |
| Simultaneous determination of zonisamide, carbamazepine and carbamazepine-10,11-epoxide in infant serum by high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20060616 |
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| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Zonisamide prophylaxis in refractory pediatric headache. | Headache 20060501 |
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| Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. | Bioorganic & medicinal chemistry letters 20060415 |
| Modern antiepileptic drugs: guidelines and beyond. | Current opinion in neurology 20060401 |
| Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. | Journal of medicinal chemistry 20060323 |
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| Zonisamide-induced suicidal ideation. | Psychosomatics 20060101 |
| Serum aminotransferase activity as a predictor for estimation of total clearance of hepatically metabolized drugs in rats with acute hepatic failure. | Biological & pharmaceutical bulletin 20060101 |
| Pharmacologic treatment of obesity. | Advances in psychosomatic medicine 20060101 |
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| Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age. | Clinical pharmacokinetics 20060101 |
| Drug monitoring and toxicology: a procedure for the monitoring of levetiracetam and zonisamide by HPLC-UV. | Journal of analytical toxicology 20060101 |
| [Carbamazepine-induced systemic lupus erythematosus--a case report]. | Neurologia i neurochirurgia polska 20060101 |
| Post traumatic epilepsy: a review of scientific evidence. | Indian journal of physiology and pharmacology 20060101 |
| Obesity: new perspectives and pharmacotherapies. | Cardiology in review 20060101 |
| Antiepileptic drugs and bone metabolism. | Nutrition & metabolism 20060101 |
| Structural brain abnormalities in juvenile myoclonic epilepsy patients: volumetry and voxel-based morphometry. | Korean journal of radiology 20060101 |
| Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? | Clinical pharmacokinetics 20060101 |
| A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. | PloS one 20060101 |
| Antiepileptic drugs and neuroprotection: current status and future roles. | Epilepsy & behavior : E&B 20051201 |
| Effects of zonisamide on neurotransmitter exocytosis associated with ryanodine receptors. | Epilepsy research 20051201 |
| Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures. | Brain research. Brain research protocols 20051201 |
| Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction. | European journal of clinical pharmacology 20051201 |
| An infantile case of Sturge-Weber syndrome in association with Klippel-Trenaunay-Weber syndrome and phakomatosis pigmentovascularis. | Journal of Korean medical science 20051201 |
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| Gender aspects of pharmacokinetics of new and old AEDs: pregnancy and breast-feeding. | Therapeutic drug monitoring 20051201 |
| Treatment of pediatric epilepsy: expert opinion, 2005. | Journal of child neurology 20051201 |
| Drug-induced weight gain. | Timely topics in medicine. Cardiovascular diseases 20051028 |
| Zonisamide add-on for drug-resistant partial epilepsy. | The Cochrane database of systematic reviews 20051019 |
| Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. | Neuropeptides 20051001 |
| Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in rats. | Brain research 20050928 |
| Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. | Bioorganic & medicinal chemistry letters 20050901 |
| In vivo evaluation of the effect of zonisamide on the hippocampal redox state during kainic acid-induced seizure status in rats. | Neurochemical research 20050901 |
| Zonisamide: review of its use in epilepsy therapy. | Drugs of today (Barcelona, Spain : 1998) 20050901 |
| High-performance liquid chromatography method for the quantification of pantoprazole in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805 |
| Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release. | Brain research 20050802 |
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| Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. | Naunyn-Schmiedeberg's archives of pharmacology 20050801 |
| Drug-induced weight gain. | Drugs of today (Barcelona, Spain : 1998) 20050801 |
| Lithium differs from anticonvulsant mood stabilizers in prefrontal cortical and accumbal dopamine release: role of 5-HT(1A) receptor agonism. | Brain research 20050712 |
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| Efficacy of levetiracetam at 12 months in children classified by seizure type, cognitive status, and previous anticonvulsant drug use. | Journal of child neurology 20050701 |
| Broad-spectrum efficacy of zonisamide at 12 months in children with intractable epilepsy. | Journal of child neurology 20050701 |
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| Comparison of the effects of anticonvulsant drugs with diverse mechanisms of action in the formalin test in rats. | Neuropharmacology 20050601 |
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| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Anticonvulsant drug therapies. | Journal of psychosocial nursing and mental health services 20050601 |
| Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. | Bioorganic & medicinal chemistry letters 20050502 |
| Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial. | The Journal of clinical psychiatry 20050501 |
| Meta-analysis: pharmacologic treatment of obesity. | Annals of internal medicine 20050405 |
| Lack of clinically significant pharmacokinetic interactions between zonisamide and lamotrigine at steady state in patients with epilepsy. | Therapeutic drug monitoring 20050401 |
| Effect of zonisamide on essential tremor: a pilot crossover study in comparison with arotinolol. | Parkinsonism & related disorders 20050301 |
| Pharmacological therapies for obesity. | Gastroenterology clinics of North America 20050301 |
| Clinical experience with zonisamide monotherapy and adjunctive therapy in children with epilepsy at a tertiary care referral center. | Journal of child neurology 20050301 |
| Continued use of zonisamide following development of renal calculi. | Neurology 20050222 |
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| Reduced anesthetization during the intracarotid amobarbital (Wada) test in patients taking carbonic anhydrase-inhibiting medications. | Epilepsia 20050201 |
| A preliminary open-label study of zonisamide treatment for bipolar depression in 10 patients. | The Journal of clinical psychiatry 20050201 |
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| Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. | Epilepsia 20050101 |
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| Zonisamide: a review of its use in the management of partial seizures in epilepsy. | CNS drugs 20050101 |
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| Bipolar mixed states and their treatment. | Expert review of neurotherapeutics 20050101 |
| Zonisamide: physician and patient experiences. | Epilepsy research 20050101 |
| Lack of pharmacokinetic interactions between steady-state zonisamide and valproic acid in patients with epilepsy. | Clinical pharmacokinetics 20050101 |
| Zonisamide in the treatment of painful diabetic neuropathy: a randomized, double-blind, placebo-controlled pilot study. | Pain medicine (Malden, Mass.) 20050101 |
| Pharmacotherapy for obesity. | Drugs 20050101 |
| New antiepileptic drugs--an overview. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101 |
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| Zonisamide monotherapy with once-daily dosing in children with cryptogenic localization-related epilepsies: clinical effects and pharmacokinetic studies. | Seizure 20041201 |
| Review of zonisamide development in Japan. | Seizure 20041201 |
| Effects of zonisamide monotherapy in children with epilepsy. | Seizure 20041201 |
| Clinical efficacy of zonisamide in childhood epilepsy after long-term treatment: a postmarketing, multi-institutional survey. | Seizure 20041201 |
| Efficacy of zonisamide: our experience. | Seizure 20041201 |
| Zonisamide: chemistry, mechanism of action, and pharmacokinetics. | Seizure 20041201 |
| Safety of zonisamide therapy: prospective follow-up survey. | Seizure 20041201 |
| Zonisamide overview of the United States experience. | Seizure 20041201 |
| Review of United States and European clinical trials of zonisamide in the treatment of refractory partial-onset seizures. | Seizure 20041201 |
| Zonisamide clinical trials: European experience. | Seizure 20041201 |
| Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor. | Biological & pharmaceutical bulletin 20041201 |
| Effects of zonisamide on the electroencephalogram of a patient with juvenile myoclonic epilepsy. | Epilepsy & behavior : E&B 20041201 |
| Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy. | Epileptic disorders : international epilepsy journal with videotape 20041201 |
| A cautionary note when using zonisamide in youths: a case report of association with toxic epidermal necrolysis. | The Journal of clinical psychiatry 20041201 |
| Effects of the antiepileptics phenytoin and zonisamide on dentin formation and bone mineral density of the mandible in growing rats. | Methods and findings in experimental and clinical pharmacology 20041201 |
| Effect of zonisamide on the pharmacokinetics and pharmacodynamics of a combination ethinyl estradiol-norethindrone oral contraceptive in healthy women. | Clinical therapeutics 20041201 |
| Initial treatment of epilepsy: special issues in treating the elderly. | Neurology 20041123 |
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| Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients. | Epilepsy research 20041101 |
| Zonisamide and associated oligohidrosis and hyperthermia. | Epilepsy research 20041101 |
| Pure red cell aplasia after 13 years of sodium valproate, and bone marrow suppression after 17 years of carbamazepine. | PLoS medicine 20041101 |
| [Treatment guidelines for adult epilepsy]. | Rinsho shinkeigaku = Clinical neurology 20041101 |
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| Acute treatment of bipolar depression with adjunctive zonisamide: a retrospective chart review. | Bipolar disorders 20041001 |
| Anticonvulsant drugs in primary headaches prophylaxis. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001 |
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| Side effects of antiepileptics--a review. | Pain practice : the official journal of World Institute of Pain 20040901 |
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| Antinociceptive effects of sodium channel-blocking agents on acute pain in mice. | Journal of pharmacological sciences 20040601 |
| Natural antioxidants may prevent posttraumatic epilepsy: a proposal based on experimental animal studies. | Acta medica Okayama 20040601 |
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| Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital. | Current medical research and opinion 20040501 |
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| Clinical evaluation of anti-obesity drugs. | Current drug targets 20040401 |
| Successful use of zonisamide for central poststroke pain. | The journal of pain : official journal of the American Pain Society 20040401 |
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| Diabetic neuropathy: an intensive review. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040115 |
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| Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial. | The Journal of clinical psychiatry 20040101 |
| Treatment of partial seizures in childhood : an overview. | CNS drugs 20040101 |
| Novel therapeutic effects of the anti-convulsant, zonisamide, on Parkinson's disease. | Current pharmaceutical design 20040101 |
| Zonisamide therapy for refractory idiopathic epilepsy in dogs. | Journal of the American Animal Hospital Association 20040101 |
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| Statistics on deliveries of mothers with epilepsy at Yokohama City University Hospital. | Epilepsia 20040101 |
| Open-label zonisamide for refractory migraine. | Clinical neuropharmacology 20040101 |
| Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1. | Molecular membrane biology 20040101 |
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| Postoperative seizures: epidemiology, pathology, and prophylaxis. | Neurologia medico-chirurgica 20031201 |
| New anticonvulsant medication uses in bipolar disorder. | CNS spectrums 20031201 |
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| Infantile spasms. | Expert opinion on pharmacotherapy 20031101 |
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| Antiepileptic drug pharmacokinetics during pregnancy and lactation. | Neurology 20030901 |
| Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain. | The American journal of geriatric pharmacotherapy 20030901 |
| Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures. | Brain research. Molecular brain research 20030819 |
| The long-term effects of antiepileptic drugs on the visual system in rats: electrophysiological and histopathological studies. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20030801 |
| Zonisamide effective for weight loss in women. | The Journal of family practice 20030801 |
| A case of adversive seizures induced by hyperventilation. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20030801 |
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| [West's syndrome. Analysis, aetiological factors and therapeutic options]. | Revista de neurologia 20030801 |
| The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy. | Anesthesia and analgesia 20030601 |
| Therapeutic drug monitoring of the newer antiepileptic drugs. | Therapeutic drug monitoring 20030601 |
| Acute zonisamide overdose: a death revisited. | Veterinary and human toxicology 20030601 |
| Ziprasidone metabolism, aldehyde oxidase, and clinical implications. | Journal of clinical psychopharmacology 20030601 |
| Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. | The Lancet. Neurology 20030601 |
| The diverse roles of anticonvulsants in bipolar disorders. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20030601 |
| [A five-year-old girl with epilepsy showing forced normalization due to zonisamide]. | No to hattatsu = Brain and development 20030501 |
| [An autopsy case of encephalopathy associated with small cell carcinoma of the stomach with nonconvulsive status epilepticus resembling Creutzfeldt-Jakob disease]. | No to shinkei = Brain and nerve 20030501 |
| The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come? | Epileptic disorders : international epilepsy journal with videotape 20030501 |
| Zonisamide for weight loss in obese adults: a randomized controlled trial. | JAMA 20030409 |
| Effects of chronic administration of zonisamide, an antiepileptic drug, on bone mineral density and their prevention with alfacalcidol in growing rats. | Journal of pharmacological sciences 20030401 |
| Oligohydrosis and hyperthermia: pilot study of a novel topiramate adverse effect. | Journal of child neurology 20030401 |
| Therapeutics in pediatric epilepsy, Part 1: The new antiepileptic drugs and the ketogenic diet. | Mayo Clinic proceedings 20030301 |
| Review of the newer antiepileptic drugs. | The American journal of managed care 20030301 |
| Treating bipolar depression. | The Journal of family practice 20030301 |
| Effects of valproate, phenytoin, and zonisamide on clonic and tonic seizures induced by acute and repeated exposure of mice to flurothyl. | Physiology & behavior 20030301 |
| Oligohydrosis and fever in pediatric patients treated with zonisamide. | Pediatric neurology 20030301 |
| Zonisamide-induced restless legs syndrome. | Neurology 20030114 |
| Visual hallucinations associated with zonisamide. | Pharmacotherapy 20030101 |
| Effects of concomitant antiepileptic drugs on serum carbamazepine concentration in epileptic patients: quantitative analysis based on extracellular water volume as a transforming factor. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030101 |
| Selection criteria for the clinical use of the newer antiepileptic drugs. | CNS drugs 20030101 |
| Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation. | Epilepsia 20030101 |
| Efficacy of newer anticonvulsant medications in bipolar spectrum mood disorders. | The Journal of clinical psychiatry 20030101 |
| Zonisamide: a new antiepileptic drug. | Polish journal of pharmacology 20030101 |
| The evolution of antiepileptic drugs for mood stabilization and their main mechanisms of action. | Expert review of neurotherapeutics 20030101 |
| Exocytosis mechanism as a new targeting site for mechanisms of action of antiepileptic drugs. | Life sciences 20021220 |
| Antiepileptic drug therapy for adults: when to initiate and how to choose. | Mayo Clinic proceedings 20021201 |
| Combining lithium and anticonvulsants in bipolar disorder: a review. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20021201 |
| Antipsychotic, antidepressant, anxiolytic, and anticonvulsant drugs induce type II nitric oxide synthase mRNA in rat brain. | Neuroscience letters 20021129 |
| Zonisamide treatment of bipolar disorder: a case report. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20021101 |
| New antiepileptic drug therapies. | Neurologic clinics 20021101 |
| Selective mutism and obsessive compulsive disorders associated with zonisamide. | Seizure 20021001 |
| Kidney stones, carbonic anhydrase inhibitors, and the ketogenic diet. | Epilepsia 20021001 |
| Newer GABAergic agents for pharmacotherapy of infantile spasms. | Drugs of today (Barcelona, Spain : 1998) 20021001 |
| [A case of bilateral perisylvian polymicrogyria with epileptic attacks of focal inhibitory seizure followed by complex partial seizure]. | Rinsho shinkeigaku = Clinical neurology 20021001 |
| Antiepileptic drug use during the first 12 months of vagus nerve stimulation therapy: a registry study. | Neurology 20020924 |
| Use of anticonvulsants for treatment of neuropathic pain. | Neurology 20020910 |
| [Urolithiasis induced by combined ACTH and zonisamide treatment in a patient with startle induced epilepsy]. | No to hattatsu = Brain and development 20020901 |
| Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI). | Epilepsy research 20020901 |
| [Monitoring serum levels of new antiepileptics]. | Revista de neurologia 20020901 |
| Randomized controlled trial of zonisamide for the treatment of partial-onset seizures. | Neurology 20020611 |
| A possible role for zonisamide in treating neuropathic pain: a case of idiopathic polyneuropathy. | Pain practice : the official journal of World Institute of Pain 20020601 |
| Long-term response to zonisamide in patients with West syndrome. | Neurology 20020528 |
| Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20020501 |
| Clobazam shows a different antiepileptic action profile from clonazepam and zonisamide in Ihara epileptic rats. | Epilepsy research 20020501 |
| Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations. | The Journal of clinical psychiatry 20020401 |
| The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs). | Seizure 20020401 |
| Pharmacokinetics of zonisamide in perinatal period. | Brain & development 20020301 |
| Interaction between carbamazepine, zonisamide and voltage-sensitive Ca2+ channel on acetylcholine release in rat frontal cortex. | Epilepsy research 20020301 |
| Oral high-dose phenobarbital therapy for early infantile epileptic encephalopathy. | Pediatric neurology 20020301 |
| Some common issues in the use of antiepileptic drugs. | Seminars in neurology 20020301 |
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| Marketed new antiepileptic drugs: are they better than old-generation agents? | Therapeutic drug monitoring 20020201 |
| New antiepileptic drugs: review on drug interactions. | Therapeutic drug monitoring 20020201 |
| Clinical pharmacology: drugs as a benefit and/or risk in sudden unexpected death in epilepsy? | Journal of clinical pharmacology 20020201 |
| Smoldering myeloma associated with zonisamide treatment. | Internal medicine (Tokyo, Japan) 20020201 |
| [A case of epilepsy after therapy with interferon-alpha-treated chronic hepatitis C]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20020201 |
| Zonisamide in pediatric epilepsy: review of the Japanese experience. | Journal of child neurology 20020201 |
| [A case of infantile epileptic encephalopathy with frequent focal motor status convulsivus: successful treatment with zonisamide]. | No to hattatsu = Brain and development 20020101 |
| Unverricht-Lundborg disease with cystatin B gene abnormalities. | Pediatric neurology 20020101 |
| Newer therapies in the drug treatment of epilepsy. | The Annals of pharmacotherapy 20020101 |
| Effect of antiepileptic drugs on cognitive function in individuals with epilepsy: a comparative review of newer versus older agents. | Drugs 20020101 |
| Three new drugs for epilepsy: levetiracetam, oxcarbazepine, and zonisamide. | Journal of child neurology 20020101 |
| Using the new antiepilepsy drugs in children. | Journal of child neurology 20020101 |
| Interactions between antiepileptic drugs and hormonal contraception. | CNS drugs 20020101 |
| Medical treatment of patients with infantile spasms. | Clinical neuropharmacology 20020101 |
| Zonisamide add-on for drug-resistant partial epilepsy. | The Cochrane database of systematic reviews 20020101 |
| Treatment of epilepsy in women of reproductive age: pharmacokinetic considerations. | Clinical pharmacokinetics 20020101 |
| New and emerging prophylactic agents for migraine. | CNS drugs 20020101 |
| Protein-losing cytomegalovirus gastritis in a patient with Stevens-Johnson syndrome. | Digestion 20020101 |
| Pharmacokinetics of mood stabilizers and new anticonvulsants. | Psychopharmacology bulletin 20020101 |
| A casuistic rationale for the treatment of spastic and myocloni in a childhood neurodegenerative disease: neuronal ceroid lipofuscinosis of the type Jansky-Bielschowsky. | Neuro endocrinology letters 20020101 |
| New migraine preventive options: an update with pathophysiological considerations. | Revista do Hospital das Clinicas 20020101 |
| Zonisamide has beneficial effects on Parkinson's disease patients. | Neuroscience research 20011201 |
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| Zonisamide as a neuroprotective agent in an adult gerbil model of global forebrain ischemia: a histological, in vivo microdialysis and behavioral study. | Brain research 19971003 |
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| The genetic animal model of reflex epilepsy in the Mongolian gerbil: differential efficacy of new anticonvulsive drugs and prototype antiepileptics. | Pharmacological research communications 19870601 |
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