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66082-05-1

66082-05-1 | poly(ethyleneglycol-lactide)

CAS No: 66082-05-1 Catalog No: AG00FXF6 MDL No:

Product Description

Catalog Number:
AG00FXF6
Chemical Name:
poly(ethyleneglycol-lactide)
CAS Number:
66082-05-1
IUPAC Name:
(3S,6S)-3,6-dimethyl-1,4-dioxane-2,5-dione;ethane-1,2-diol
InChI:
InChI=1S/C6H8O4.C2H6O2/c1-3-5(7)10-4(2)6(8)9-3;3-1-2-4/h3-4H,1-2H3;3-4H,1-2H2/t3-,4-;/m0./s1
InChI Key:
YBAGJSUAYPAYFG-MMALYQPHSA-N

Properties

Complexity:
161  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
206.079g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
206.194g/mol
Monoisotopic Mass:
206.079g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
93.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
Mesoscale simulation of the effect of a lactide segment on the nanostructure of star poly(ethylene glycol-co-lactide)-acrylate macromonomers in aqueous solution. The journal of physical chemistry. B 20120209
Polymer--cisplatin conjugate nanoparticles for acid-responsive drug delivery. ACS nano 20100126
Investigation of endocytosis and cytotoxicity of poly-d, l-lactide-poly(ethylene glycol) micro/nano-particles in osteoblast cells. International journal of nanomedicine 20100101
Synthesis and characterization of star poly(epsilon-caprolactone)-b-poly(ethylene glycol) and poly(L-lactide)-b-poly(ethylene glycol) copolymers: evaluation as drug delivery carriers. Bioconjugate chemistry 20080701
Amphotericin B-loaded poly(ethylene glycol)-poly(lactide) micelles: preparation, freeze-drying, and in vitro release. Journal of biomedical materials research. Part A 20080501
Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells. Journal of controlled release : official journal of the Controlled Release Society 20071008
Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model. International journal of pharmaceutics 20060831
In vitro and in vivo biologic evaluation of long-circulating biodegradable drug carriers loaded with the pure antiestrogen RU 58668. International journal of cancer 20030901
Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study. Bioconjugate chemistry 20030101
Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu. Journal of controlled release : official journal of the Controlled Release Society 20020821
In vivo biocompatibility studies of poly(D,L-lactide)/poly(ethylene glycol)-poly(L-lactide) microspheres containing all-trans-retinoic acid. Journal of biomaterials science. Polymer edition 20020101
Production of insulin-loaded poly(ethylene glycol)/poly(l-lactide) (PEG/PLA) nanoparticles by gas antisolvent techniques. Journal of pharmaceutical sciences 20011001
Liposomal anthracyclines for breast cancer. Seminars in oncology 20010801
Poly(ethylene glycol)-poly(L-lactide) diblock copolymer prevents aggregation of poly(L-lactide) microspheres during ethylene oxide gas sterilization. Biomaterials 20010501
Effects of ethylene oxide gas sterilization on physical properties of poly(L-lactide)-poly(ethylene glycol)-poly(L-lactide) microspheres. Journal of biomaterials science. Polymer edition 20010101

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