200,000+ products from a single source!

sales@angenechem.com

Home > Pyridines > 66-72-8

66-72-8

66-72-8 | pyridoxal

CAS No: 66-72-8 Catalog No: AG00FGJ7 MDL No:MFCD00464806

Product Description

Catalog Number:
AG00FGJ7
Chemical Name:
pyridoxal
CAS Number:
66-72-8
Molecular Formula:
C8H9NO3
Molecular Weight:
167.1620
MDL Number:
MFCD00464806
IUPAC Name:
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde
InChI:
InChI=1S/C8H9NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,4,10,12H,3H2,1H3
InChI Key:
RADKZDMFGJYCBB-UHFFFAOYSA-N
SMILES:
O=Cc1c(CO)cnc(c1O)C
EC Number:
200-630-8
UNII:
3THM379K8A

Properties

Complexity:
162  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
167.058g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
167.164g/mol
Monoisotopic Mass:
167.058g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
70.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0

Literature

Title Journal
Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds. Toxicology letters 20161116
Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase. The Journal of biological chemistry 20121102
Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii. Molecules and cells 20121031
Metal ion dependency of serine racemase from Dictyostelium discoideum. Amino acids 20121001
Structural insights into catalysis by βC-S lyase from Streptococcus anginosus. Proteins 20121001
Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome. Molecular microbiology 20121001
Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20121001
Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines. Journal of medicinal chemistry 20120927
Structural analysis of the substrate recognition mechanism in O-phosphoserine sulfhydrylase from the hyperthermophilic archaeon Aeropyrum pernix K1. Journal of molecular biology 20120907
Changes in physiology and protein abundance in salt-stressed wheat chloroplasts. Molecular biology reports 20120901
Prognostic impact of vitamin B6 metabolism in lung cancer. Cell reports 20120830
Structural determinants of the β-selectivity of a bacterial aminotransferase. The Journal of biological chemistry 20120817
Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC-MS/MS) for the rapid, simultaneous analysis of thiamin, riboflavin, flavin adenine dinucleotide, nicotinamide and pyridoxal in human milk. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120815
Effect of the disease-causing R266K mutation on the heme and PLP environments of human cystathionine β-synthase. Biochemistry 20120814
Decarboxylation mechanisms in biological system. Bioorganic chemistry 20120801
Characterization of an acid phosphatase responsible for hydrolysis of pyridoxal 5'-phosphate in tobacco plants. Plant physiology and biochemistry : PPB 20120801
Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats. Diabetes 20120801
EDTA-dependent pseudothrombocytopenia: further insights and recommendations for prevention of a clinically threatening artifact. Clinical chemistry and laboratory medicine 20120801
Design and synthesis of potential mechanism-based inhibitors of the aminotransferase BioA involved in biotin biosynthesis. The Journal of organic chemistry 20120720
Theoretical study on HF elimination and aromatization mechanisms: a case of pyridoxal 5' phosphate-dependent enzyme. The Journal of organic chemistry 20120706
Vitamin B6 vitamer concentrations in cerebrospinal fluid differ between preterm and term newborn infants. Pediatrics 20120701
Crystal structure and substrate specificity of the thermophilic serine:pyruvate aminotransferase from Sulfolobus solfataricus. Acta crystallographica. Section D, Biological crystallography 20120701
The role of vitamin B6 as an antioxidant in the presence of vitamin B2-photogenerated reactive oxygen species. A kinetic and mechanistic study. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601
Increased DNA-glycation in type 2 diabetic patients: the effect of thiamine and pyridoxine therapy. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20120601
D-serine-dehydratase from Saccaromyces cerevisiae: a pyridoxal 5'- phosphate-dependent enzyme for advanced biotech applications. Protein and peptide letters 20120601
The peroxisomal NAD+ carrier of Arabidopsis thaliana transports coenzyme A and its derivatives. Journal of bioenergetics and biomembranes 20120601
Turning 'on' and 'off' a pyridoxal 5'-phosphate mimic using light. Angewandte Chemie (International ed. in English) 20120529
Synthesis, spectroscopic characterization, insulin-enhancment, and competitive DNA binding activity of a new Zn(II) complex with a vitamin B6 derivative--a new fluorescence probe for Zn(II). Dalton transactions (Cambridge, England : 2003) 20120507
Proteomic characterization of histotroph during the preimplantation phase of the estrous cycle in cattle. Journal of proteome research 20120504
Studies on molecular structure and tautomerism of a vitamin B6 analog with density functional theory. Journal of molecular modeling 20120501
The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients. Neurochemical research 20120501
3'-axial CH2 OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why. Chemical biology & drug design 20120501
Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis. Acta crystallographica. Section D, Biological crystallography 20120501
Use of differential scanning fluorimetry to optimize the purification and crystallization of PLP-dependent enzymes. Acta crystallographica. Section F, Structural biology and crystallization communications 20120501
A novel mutation of human liver alanine:glyoxylate aminotransferase causes primary hyperoxaluria type 1: immunohistochemical quantification and subcellular distribution. Acta histochemica et cytochemica 20120426
Novel structural arrangement of nematode cystathionine β-synthases: characterization of Caenorhabditis elegans CBS-1. The Biochemical journal 20120415
Thermal decomposition of pyridoxine: an evolved gas analysis-ion attachment mass spectrometry study. Rapid communications in mass spectrometry : RCM 20120415
Lipid glycation and protein glycation in diabetes and atherosclerosis. Amino acids 20120401
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. Amino acids 20120401
The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+. The Biochemical journal 20120401
Programmed cell death induced by high levels of cytokinin in Arabidopsis cultured cells is mediated by the cytokinin receptor CRE1/AHK4. Journal of experimental botany 20120401
Overexpression, crystallization and preliminary X-ray crystallographic analysis of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii. Acta crystallographica. Section F, Structural biology and crystallization communications 20120401
Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex. Archives of biochemistry and biophysics 20120315
Enzyme-replacement therapy in life-threatening hypophosphatasia. The New England journal of medicine 20120308
Preparation of encapsulated alliinase in alginate microparticles. Biotechnology letters 20120301
Individual vitamin B6 contents in selected Japanese sushi toppings. International journal of food sciences and nutrition 20120301
Crystal structure of D-serine dehydratase from Escherichia coli. Biochimica et biophysica acta 20120301
Formation of Schiff bases of O-phosphorylethanolamine and O-phospho-D,L-serine with pyridoxal 5'-phosphate. experimental and theoretical studies. The journal of physical chemistry. A 20120301
Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implications. Journal of molecular medicine (Berlin, Germany) 20120301
Hypophosphatasia presenting with pyridoxine-responsive seizures, hypercalcemia, and pseudotumor cerebri: case report. Journal of clinical research in pediatric endocrinology 20120301
Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. PLoS pathogens 20120301
Functional significance of some particular amino acid residues in Bombyx mori pyridoxal kinase. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120201
Role of zinc ion for catalytic activity in d-serine dehydratase from Saccharomyces cerevisiae. The FEBS journal 20120201
Kinetic modeling of storage effects on biomarkers related to B vitamin status and one-carbon metabolism. Clinical chemistry 20120201
Type 1 diabetes impairs vitamin B(6) metabolism at an early stage of women's adulthood. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20120201
Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing. PLoS neglected tropical diseases 20120201
Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica. PLoS neglected tropical diseases 20120201
Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions. The Journal of biological chemistry 20120127
Quantification of vitamin B6 vitamers in human cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry. Analytica chimica acta 20120127
Protein domain structure uncovers the origin of aerobic metabolism and the rise of planetary oxygen. Structure (London, England : 1993) 20120111
Divergence and convergence in enzyme evolution. The Journal of biological chemistry 20120102
Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics. Journal of neural transmission (Vienna, Austria : 1996) 20120101
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with primary hyperoxaluria type I. Molecular genetics and metabolism 20120101
Pyridoxal 5'-phosphate (PLP) deficiency might contribute to the onset of type I diabetes. Medical hypotheses 20120101
Molecular insights into primary hyperoxaluria type 1 pathogenesis. Frontiers in bioscience (Landmark edition) 20120101
Biomedical aspects of pyridoxal 5'-phosphate availability. Frontiers in bioscience (Elite edition) 20120101
Crystallization and preliminary X-ray analysis of pyridoxine 4-oxidase, the first enzyme in pyridoxine degradation pathway I. Acta crystallographica. Section F, Structural biology and crystallization communications 20120101
γ-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis. PloS one 20120101
Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus. PLoS pathogens 20120101
Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase. PloS one 20120101
Transaminases for the synthesis of enantiopure beta-amino acids. AMB Express 20120101
Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase. PloS one 20120101
Expression, immobilization and enzymatic properties of glutamate decarboxylase fused to a cellulose-binding domain. International journal of molecular sciences 20120101
Biological conversion assay using Clostridium phytofermentans to estimate plant feedstock quality. Biotechnology for biofuels 20120101
Plasma pyridoxal 5'-phosphate is not associated with inflammatory and immune responses after adjusting for serum albumin in patients with rheumatoid arthritis: a preliminary study. Annals of nutrition & metabolism 20120101
Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2. Viruses 20120101
Characterization of spontaneous bone marrow recovery after sublethal total body irradiation: importance of the osteoblastic/adipocytic balance. PloS one 20120101
Identification of a novel gene product that promotes survival of Mycobacterium smegmatis in macrophages. PloS one 20120101
Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. PloS one 20120101
Sphingolipid and ceramide homeostasis: potential therapeutic targets. Biochemistry research international 20120101
Serine hydroxymethyltransferase from the cold adapted microorganism Psychromonas ingrahamii: a low temperature active enzyme with broad substrate specificity. International journal of molecular sciences 20120101
Acute oral toxicity evaluations of some zinc(II) complexes derived from 1-(2-salicylaldiminoethyl)piperazine Schiff bases in rats. International journal of molecular sciences 20120101
Managing your wine fermentation to reduce the risk of biogenic amine formation. Frontiers in microbiology 20120101
Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission. PloS one 20120101
GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence. PloS one 20120101
The regulatory repertoire of Pseudomonas aeruginosa AmpC ß-lactamase regulator AmpR includes virulence genes. PloS one 20120101
All-enzymatic HPLC method for determination of individual and total contents of vitamin B(6) in foods. Food & nutrition research 20120101
Vitamin Supplement - Editorial. Food & nutrition research 20120101
Accounting for differences in the bioactivity and bioavailability of vitamers. Food & nutrition research 20120101
Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1. International journal of cell biology 20120101
Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model. TheScientificWorldJournal 20120101
Application of CZE Method in Routine Analysis for Determination of B-Complex Vitamins in Pharmaceutical and Veterinary Preparations. International journal of analytical chemistry 20120101
Current view on phytoplasma genomes and encoded metabolism. TheScientificWorldJournal 20120101
Prosthetic rehabilitation of a young patient with Hypophosphatasia - A review and case report. Contemporary clinical dentistry 20120101
Peroxisomal alanine: glyoxylate aminotransferase AGT1 is indispensable for appressorium function of the rice blast pathogen, Magnaporthe oryzae. PloS one 20120101
Haematological and biochemical reference values for healthy adults in the middle belt of Ghana. PloS one 20120101
[Schizophrenia and carbonyl stress]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20120101
Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation. PloS one 20120101
Structural and mutational studies on substrate specificity and catalysis of Salmonella typhimurium D-cysteine desulfhydrase. PloS one 20120101
Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases. Frontiers in pharmacology 20120101
Enzymatic synthesis oF L-tryptophan from D,L-2-amino-delta2-thiazoline-4-carboxylic acid and indole by Pseudomonas sp. TS1138 L-2-amino-delta2-thiazoline-4-carboxylic acid hydrolase, S-carbamyl-L-cysteine amidohydrolase, and Escherichia coli L-tryptophanase. Prikladnaia biokhimiia i mikrobiologiia 20120101
Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia. Current gerontology and geriatrics research 20120101
Acceleration of anaerobic cysteine transformations to sulfane sulfur consequent to γ-glutamyl transpeptidase inhibition. TheScientificWorldJournal 20120101
Application of optical biosensors in small-molecule screening activities. Sensors (Basel, Switzerland) 20120101
Focused review: agmatine in fermented foods. Frontiers in microbiology 20120101
Fusion-triggered switching of enzymatic activity on an artificial cell membrane. Sensors (Basel, Switzerland) 20120101
Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase. PloS one 20120101
Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. PloS one 20120101
Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate. International journal of nanomedicine 20120101
Sensory dysfunction of bladder mucosa and bladder oversensitivity in a rat model of metabolic syndrome. PloS one 20120101
Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants. PloS one 20120101
Novel carbon-carbon bond formations for biocatalysis. Current opinion in biotechnology 20111201
Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency. Journal of inherited metabolic disease 20111201
Status epilepticus in a neonate treated with pyridoxine because of a familial recurrence risk for antiquitin deficiency: pyridoxine toxicity? Developmental medicine and child neurology 20111201
Interconversions of different forms of vitamin B6 in tobacco plants. Phytochemistry 20111201
N,N'-dipyridoxyl Schiff bases: synthesis, experimental and theoretical characterization. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111201
Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis. Journal of the American Chemical Society 20111116
Characterization of the side-chain hydroxyl moieties of residues Y56, Y111, Y238, Y338, and S339 as determinants of specificity in E. coli cystathionine β-lyase. Biochemistry 20111115
Serine hydroxymethyltransferase: a model enzyme for mechanistic, structural, and evolutionary studies. Biochimica et biophysica acta 20111101
Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria. Amino acids 20111101
Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase. Amino acids 20111101
Human liver peroxisomal alanine:glyoxylate aminotransferase: characterization of the two allelic forms and their pathogenic variants. Biochimica et biophysica acta 20111101
Vitamin B(6) salvage enzymes: mechanism, structure and regulation. Biochimica et biophysica acta 20111101
Serine racemase and the serine shuttle between neurons and astrocytes. Biochimica et biophysica acta 20111101
PLP-dependent H(2)S biogenesis. Biochimica et biophysica acta 20111101
Structural insights for the substrate recognition mechanism of LL-diaminopimelate aminotransferase. Biochimica et biophysica acta 20111101
The enzymes of the transsulfuration pathways: active-site characterizations. Biochimica et biophysica acta 20111101
The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase. Biochimica et biophysica acta 20111101
Molecular dynamics simulations of the intramolecular proton transfer and carbanion stabilization in the pyridoxal 5'-phosphate dependent enzymes L-dopa decarboxylase and alanine racemase. Biochimica et biophysica acta 20111101
Critical hydrogen bonds and protonation states of pyridoxal 5'-phosphate revealed by NMR. Biochimica et biophysica acta 20111101
Mathematical representation of fluorescence intensity of probes in aqueous binary solvent mixtures. Journal of fluorescence 20111101
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM). Molecular genetics and metabolism 20111101
Rapid determination of free D-serine with chicken D-serine dehydratase. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide. Alcohol and alcoholism (Oxford, Oxfordshire) 20111101
Vitamin B6s inhibit oxidative stress caused by Alzheimer's disease-related Cu(II)-β-amyloid complexes-cooperative action of phospho-moiety. Bioorganic & medicinal chemistry letters 20111101
Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. Plant physiology 20111101
Effects of hydrogen sulfide synthesis inhibitors on posthypoxic ventilatory behavior in the C57BL/6J mouse. Respiration; international review of thoracic diseases 20111101
Characterization of enzymes involved in the interconversions of different forms of vitamin B(6) in tobacco leaves. Plant physiology and biochemistry : PPB 20111101
Crystallographic snapshots of tyrosine phenol-lyase show that substrate strain plays a role in C-C bond cleavage. Journal of the American Chemical Society 20111019
Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli. The Biochemical journal 20111015
Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chemical reviews 20111012
Mechanism of formation of the internal aldimine in pyridoxal 5'-phosphate-dependent enzymes. Journal of the American Chemical Society 20111005
Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney international 20111001
Brain proteome alterations of Atlantic cod (Gadus morhua) exposed to PCB 153. Aquatic toxicology (Amsterdam, Netherlands) 20111001
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes. Acta crystallographica. Section D, Biological crystallography 20111001
Oral contraceptive use: impact on folate, vitamin B₆, and vitamin B₁₂ status. Nutrition reviews 20111001
Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate. Journal of the American Chemical Society 20110921
Mechanistic studies on the enzymatic processing of fluorinated methionine analogues by Trichomonas vaginalis methionine γ-lyase. The Biochemical journal 20110915
A continuous fluorescence displacement assay for BioA: an enzyme involved in biotin biosynthesis. Analytical biochemistry 20110901
Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways. Neurochemistry international 20110901
Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates. Biochimica et biophysica acta 20110901
Differential inhibition/inactivation of mitochondrial complex I implicates its alteration in malignant cells. Biochemistry. Biokhimiia 20110901
Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney. The Journal of biological chemistry 20110805
Cerebrospinal fluid and serum levels of vitamin B6 in status epilepticus children. Brain & development 20110801
Higher plasma pyridoxal 5'-phosphate is associated with better blood glucose responses in critically ill surgical patients with inadequate vitamin B-6 status. Clinical nutrition (Edinburgh, Scotland) 20110801
The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. Molecular biology and evolution 20110801
A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. European journal of cancer (Oxford, England : 1990) 20110801
Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6. Toxicology in vitro : an international journal published in association with BIBRA 20110801
Release of membrane-associated L-dopa decarboxylase from human cells. Neurochemical research 20110801
Pyridoxine supply in human development. Seminars in cell & developmental biology 20110801
Crystal structures of open and closed forms of d-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis. The FEBS journal 20110801
Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi. Applied microbiology and biotechnology 20110801
Biomarkers related to one-carbon metabolism as potential risk factors for distal colorectal adenomas. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110801
Understanding non-enzymatic aminophospholipid glycation and its inhibition. Polar head features affect the kinetics of Schiff base formation. Bioorganic & medicinal chemistry 20110801
The role of nonenzymatic glycation and carbonyls in collagen cross-linking for the treatment of keratoconus. Investigative ophthalmology & visual science 20110801
Modes of action of microbially-produced phytotoxins. Toxins 20110801
γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage. Chemical research in toxicology 20110718
Synthesis, characterization, reactivity and catalytic activity of oxidovanadium(IV), oxidovanadium(V) and dioxidovanadium(V) complexes of benzimidazole modified ligands. Dalton transactions (Cambridge, England : 2003) 20110714
Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: internal aldimine and stable L-aspartate external aldimine. Biochemistry 20110705
Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis. American journal of physiology. Gastrointestinal and liver physiology 20110701
root uv-b sensitive mutants are suppressed by specific mutations in ASPARTATE AMINOTRANSFERASE2 and by exogenous vitamin B6. Molecular plant 20110701
Characterization and regulation of a bacterial sugar phosphatase of the haloalkanoate dehalogenase superfamily, AraL, from Bacillus subtilis. The FEBS journal 20110701
Functional asymmetry for the active sites of linked 5-aminolevulinate synthase and 8-amino-7-oxononanoate synthase. Archives of biochemistry and biophysics 20110701
Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors. Applied microbiology and biotechnology 20110701
Role of a conserved arginine residue during catalysis in serine palmitoyltransferase. FEBS letters 20110623
Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents. Amino acids 20110601
Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. Amino acids 20110601
Protein crystal microspectrophotometry. Biochimica et biophysica acta 20110601
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors. The FEBS journal 20110601
Sulfur- and seleno-containing amino acids. Amino acids 20110601
Use of different stationary phases for separation of isoniazid, its metabolites and vitamin B6 forms. Journal of separation science 20110601
In vivo diagnosis of colonic precancer and cancer using near-infrared autofluorescence spectroscopy and biochemical modeling. Journal of biomedical optics 20110601
Oxidovanadium(IV) Schiff base complex derived from vitamin B6: synthesis, characterization, and insulin enhancing properties. Inorganic chemistry 20110516
Pyridoxine enhances cell proliferation and neuroblast differentiation by upregulating the GABAergic system in the mouse dentate gyrus. Neurochemical research 20110501
Role of aromatic aldehyde synthase in wounding/herbivory response and flower scent production in different Arabidopsis ecotypes. The Plant journal : for cell and molecular biology 20110501
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. European journal of medicinal chemistry 20110501
Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis. Plant molecular biology 20110501
Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine γ-lyase with substrates. Biochemistry. Biokhimiia 20110501
Multiphoton manipulations of enzymatic photoactivity in aspartate aminotransferase. The journal of physical chemistry. B 20110421
A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the Aplysia californica central nervous system. The Journal of biological chemistry 20110415
Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease. The Journal of biological chemistry 20110408
A public resource for metabolic pathway mapping of Aspergillus fumigatus Af293. Medical mycology 20110401
Discovery and characterization of D-phenylserine deaminase from Arthrobacter sp. TKS1. Applied microbiology and biotechnology 20110401
Long-term prednisolone treatments increase bioactive vitamin B6 synthesis in vivo. The Journal of pharmacology and experimental therapeutics 20110401
Hydrogen sulfide generation in mammals: the molecular biology of cystathionine-β- synthase (CBS) and cystathionine-γ-lyase (CSE). Inflammation & allergy drug targets 20110401
Pyridoxal 5'-phosphate in cerebrospinal fluid; factors affecting concentration. Journal of inherited metabolic disease 20110401
Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction--in vitro and in vivo. Experimental biology and medicine (Maywood, N.J.) 20110401
Kinetic isotope effects of L-Dopa decarboxylase. Journal of the American Chemical Society 20110330
Mechanistic studies of 1-aminocyclopropane-1-carboxylate deaminase: characterization of an unusual pyridoxal 5'-phosphate-dependent reaction. Biochemistry 20110322
Chelators to the rescue: different horses for different courses! Chemical research in toxicology 20110321
Substituent effects on electrophilic catalysis by the carbonyl group: anatomy of the rate acceleration for PLP-catalyzed deprotonation of glycine. Journal of the American Chemical Society 20110309
Effect of ultrasound on the activity of alliinase from fresh garlic. Ultrasonics sonochemistry 20110301
Plasma pyridoxal 5'-phosphate is not correlated with hemoglobin during pyridoxine supplementation in patients with rheumatoid arthritis. European journal of clinical nutrition 20110301
Emerging knowledge of regulatory roles of D-amino acids in bacteria. Cellular and molecular life sciences : CMLS 20110301
Electroencephalographic and seizure manifestations of pyridoxal 5'-phosphate-dependent epilepsy. Epilepsy & behavior : E&B 20110301
Manganese-enhanced MRI predicts the histological grade of hepatocellular carcinoma in potential surgical candidates. Clinical radiology 20110301
Vitamin B6 deficiency: a potential cause of refractory seizures in adults. JPEN. Journal of parenteral and enteral nutrition 20110301
[Studies on pathophysiology of schizophrenia with a rare variant as a clue]. Brain and nerve = Shinkei kenkyu no shinpo 20110301
Structure-based development of specific inhibitors for individual cathepsins and their medical applications. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110210
Restoring assembly and activity of cystathionine β-synthase mutants by ligands and chemical chaperones. Journal of inherited metabolic disease 20110201
Determination of cystathionine beta-synthase activity in human plasma by LC-MS/MS: potential use in diagnosis of CBS deficiency. Journal of inherited metabolic disease 20110201
Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases. Biotechnology and bioengineering 20110201
Systemic bioavailability and pharmacokinetics of the doxylamine-pyridoxine delayed-release combination (Diclectin). Therapeutic drug monitoring 20110201
Mammalian retinal horizontal cells are unconventional GABAergic neurons. Journal of neurochemistry 20110201
Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction. Journal of computer-aided molecular design 20110201
Advances pertaining to the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors. Journal of clinical psychopharmacology 20110201
Assessment of vitamin B(6) status in Korean patients with newly diagnosed type 2 diabetes. Nutrition research and practice 20110201
Product-assisted catalysis as the basis of the reaction specificity of threonine synthase. The Journal of biological chemistry 20110128
Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy. Archives of biochemistry and biophysics 20110115
Prolonged survival and phenotypic correction of Akp2(-/-) hypophosphatasia mice by lentiviral gene therapy. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110101
Positive transcriptional control of the pyridoxal phosphate biosynthesis genes pdxST by the MocR-type regulator PdxR of Corynebacterium glutamicum ATCC 13032. Microbiology (Reading, England) 20110101
The s-layer glycome-adding to the sugar coat of bacteria. International journal of microbiology 20110101
The role of system-specific molecular chaperones in the maturation of molybdoenzymes in bacteria. Biochemistry research international 20110101
Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment. BMC medicine 20110101
Long-term effects of environmentally relevant doses of 2,2',4,4',5,5' hexachlorobiphenyl (PCB153) on neurobehavioural development, health and spontaneous behaviour in maternally exposed mice. Behavioral and brain functions : BBF 20110101
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? International journal of biological sciences 20110101
Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids. Genome biology and evolution 20110101
Saccharomyces cerevisiae Bat1 and Bat2 aminotransferases have functionally diverged from the ancestral-like Kluyveromyces lactis orthologous enzyme. PloS one 20110101
From L-dopa to dihydroxyphenylacetaldehyde: a toxic biochemical pathway plays a vital physiological function in insects. PloS one 20110101
It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase. PloS one 20110101
The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti. Bioscience, biotechnology, and biochemistry 20110101
The salt-responsive transcriptome of chickpea roots and nodules via deepSuperSAGE. BMC plant biology 20110101
Distinct colonization patterns and cDNA-AFLP transcriptome profiles in compatible and incompatible interactions between melon and different races of Fusarium oxysporum f. sp. melonis. BMC genomics 20110101
Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. PloS one 20110101
Bacterial distribution in the rhizosphere of wild barley under contrasting microclimates. PloS one 20110101
High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway. Lipids in health and disease 20110101
A dopa decarboxylase modulating the immune response of scallop Chlamys farreri. PloS one 20110101
Integrin Targeted MR Imaging. Theranostics 20110101
Critical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor. PloS one 20110101
Decreased GABAB receptor function in the cerebellum and brain stem of hypoxic neonatal rats: role of glucose, oxygen and epinephrine resuscitation. Journal of biomedical science 20110101
The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease. Enzyme research 20110101
HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells. Retrovirology 20110101
Comparative thermodynamic studies on substrate and product binding of O-acetylserine sulfhydrylase reveals two different ligand recognition modes. BMC biochemistry 20110101
Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PloS one 20110101
New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis. PloS one 20110101
Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutrition & metabolism 20110101
A rapid, simple method for the genetic discrimination of intact Arabidopsis thaliana mutant seeds using metabolic profiling by direct analysis in real-time mass spectrometry. Plant methods 20110101
Frontiers in vitamin research: new antibodies, new data. TheScientificWorldJournal 20110101
Global proteomic analysis of two tick-borne emerging zoonotic agents: anaplasma phagocytophilum and ehrlichia chaffeensis. Frontiers in microbiology 20110101
Trypanosoma cruzi Coexpressing Ornithine Decarboxylase and Green Fluorescence Proteins as a Tool to Study the Role of Polyamines in Chagas Disease Pathology. Enzyme research 20110101
Zingiber officinale acts as a nutraceutical agent against liver fibrosis. Nutrition & metabolism 20110101
Diploid-specific [corrected] genome stability genes of S. cerevisiae: genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress. PloS one 20110101
Elevated maternal serum folate in the third trimester and reduced fetal growth: a longitudinal study. Journal of nutritional science and vitaminology 20110101
Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. PloS one 20110101
Dyslipidemia as a contributory factor in etiopathogenesis of diabetic neuropathy. Indian journal of endocrinology and metabolism 20110101
Ictal but not interictal epileptic discharges activate astrocyte endfeet and elicit cerebral arteriole responses. Frontiers in cellular neuroscience 20110101
Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways. PloS one 20110101
Management of diabetic small-fiber neuropathy with combination L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate. Reviews in neurological diseases 20110101
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs. Molecular systems biology 20110101
Sensing and adaptation to low pH mediated by inducible amino acid decarboxylases in Salmonella. PloS one 20110101
Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathway. PloS one 20110101
A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PloS one 20110101
Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation. BMC genomics 20110101
The representation of protein complexes in the Protein Ontology (PRO). BMC bioinformatics 20110101
Minimal antizyme peptide fully functioning in the binding and inhibition of ornithine decarboxylase and antizyme inhibitor. PloS one 20110101
Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: spatial conservation of an active site tyrosine and classification of two types of enzyme. PloS one 20110101
Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence. Veterinary research 20110101
Rapid development of new protein biosensors utilizing peptides obtained via phage display. PloS one 20110101
Clinical proteomics of the neglected human malarial parasite Plasmodium vivax. PloS one 20110101
Determinants of the differential antizyme-binding affinity of ornithine decarboxylase. PloS one 20110101
Mangafodipir protects against hepatic ischemia-reperfusion injury in mice. PloS one 20110101
Genome economization in the endosymbiont of the wood roach Cryptocercus punctulatus due to drastic loss of amino acid synthesis capabilities. Genome biology and evolution 20110101
Differential expression of cysteine desulfurases in soybean. BMC plant biology 20110101
Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity. PloS one 20110101
Catalytic site cysteines of thiol enzyme: sulfurtransferases. Journal of amino acids 20110101
NMR studies of the stability, protonation States, and tautomerism of (13)C- AND (15)N-labeled aldimines of the coenzyme pyridoxal 5'-phosphate in water. Biochemistry 20101228
Structural insights into the catalytic mechanism of the yeast pyridoxal 5-phosphate synthase Snz1. The Biochemical journal 20101215
Cross-talk between the catalytic core and the regulatory domain in cystathionine β-synthase: study by differential covalent labeling and computational modeling. Biochemistry 20101214
Preliminary report: hyperhomocysteinemia in patients with acute intermittent porphyria. Metabolism: clinical and experimental 20101201
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant. Biochimie 20101201
Purification, characterization and amino acid sequence of a novel enzyme, D-threo-3-hydroxyaspartate dehydratase, from Delftia sp. HT23. Journal of biochemistry 20101201
Identification of evolutionarily conserved genetic regulators of cellular aging. Aging cell 20101201
Light-enhanced catalysis by pyridoxal phosphate-dependent aspartate aminotransferase. Journal of the American Chemical Society 20101201
Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library. Journal of the American Chemical Society 20101201
Effects of folic acid supplementation to rations differing in the concentrate to roughage ratio on ruminal fermentation, nutrient flow at the duodenum, and on serum and milk variables of dairy cows. Archives of animal nutrition 20101201
A randomized, double-blind, crossover study on the pharmacokinetics of a novel formulation of CoQ₁₀ with pyridoxal 5'-phosphate and phosphatidyl choline. Journal of dietary supplements 20101201
Identification and characterization of two families of F420 H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation. Molecular microbiology 20101101
Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis. Molecular microbiology 20101101
Structural interpretation of P2X receptor mutagenesis studies on drug action. British journal of pharmacology 20101101
Nobuhiko Katunuma: an outstanding scientist in the field of proteolysis and warm-hearted 'Kendo Fighter' biochemist. Journal of biochemistry 20101101
Dietary intake of vitamin B-6, plasma pyridoxal 5'-phosphate, and homocysteine in Puerto Rican adults. Journal of the American Dietetic Association 20101101
A new role for coenzyme F420 in aflatoxin reduction by soil mycobacteria. Molecular microbiology 20101101
The role of oligomerization and cooperative regulation in protein function: the case of tryptophan synthase. PLoS computational biology 20101101
Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase. FEBS letters 20101008
Polyamine biosynthesis in Phytomonas: biochemical characterisation of a very unstable ornithine decarboxylase. International journal for parasitology 20101001
Biophysical characterization of recombinant proteins: a key to higher structural genomics success. Journal of structural biology 20101001
A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Molecular genetics and metabolism 20101001
Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment. Molecular genetics and metabolism 20101001
Responses in the brain proteome of Atlantic cod (Gadus morhua) exposed to methylmercury. Aquatic toxicology (Amsterdam, Netherlands) 20101001
Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101001
Kenji Soda--researching enzymes with the spirit of an alpinist. Journal of biochemistry 20101001
Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly. Nature communications 20101001
Substituent effects on the reaction of beta-benzoylalanines with Pseudomonas fluorescens kynureninase. Biochemistry 20100914
Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase. Chemico-biological interactions 20100906
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation. Molecular bioSystems 20100901
Vitamin B(6) supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis. European journal of clinical nutrition 20100901
Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. Dialogues in clinical neuroscience 20100901
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly. Biochemistry 20100824
Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism. Free radical biology & medicine 20100815
Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. The Journal of biological chemistry 20100813
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement. Journal of medicinal chemistry 20100812
Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes 20100801
Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A. Biochemistry 20100727
Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity. Biochimica et biophysica acta 20100701
SufS protein from Haloferax volcanii involved in Fe-S cluster assembly in haloarchaea. Biochimica et biophysica acta 20100701
Seizures and paroxysmal events: symptoms pointing to the diagnosis of pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency. Developmental medicine and child neurology 20100701
Systems-wide metabolic pathway engineering in Corynebacterium glutamicum for bio-based production of diaminopentane. Metabolic engineering 20100701
Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states. Journal of neurochemistry 20100701
Cystathionine beta-synthase mutations: effect of mutation topology on folding and activity. Human mutation 20100701
Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics. Biochemistry 20100622
Comparisons of uptake and cell surface binding among pyridoxal, pyridoxine, and pyridoxamine in RAW264.7 cells. Nutrition (Burbank, Los Angeles County, Calif.) 20100601
K30, H150, and H168 are essential residues for coordinating pyridoxal 5'-phosphate of O-acetylserine sulfhydrylase from Acidithiobacillus ferrooxidans. Current microbiology 20100601
Crystallization and preliminary X-ray analysis of SDR-type pyridoxal dehydrogenase from Mesorhizobium loti. Acta crystallographica. Section F, Structural biology and crystallization communications 20100601
Enhanced carbonyl stress in a subpopulation of schizophrenia. Archives of general psychiatry 20100601
Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation. PLoS computational biology 20100601
Understanding catalytic specificity in alanine racemase from quantum mechanical and molecular mechanical simulations of the arginine 219 mutant. Biochemistry 20100511
Simplifying pyridoxal: practical methods for amino acid dynamic kinetic resolution. Organic letters 20100507
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid. Acta paediatrica (Oslo, Norway : 1992) 20100501
Electrochemical probing into cytochrome c modification with homocysteine-thiolactone. Analytical and bioanalytical chemistry 20100501
Long- and short-term effects of tobacco smoking on circulating concentrations of B vitamins. Clinical chemistry 20100501
Large conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate binding. The FEBS journal 20100501
Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design. Acta crystallographica. Section D, Biological crystallography 20100501
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. The Plant cell 20100501
Measurement of cysteine S-conjugate β-lyase activity. Current protocols in toxicology 20100501
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. The Journal of biological chemistry 20100430
Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase. The Journal of biological chemistry 20100430
Purification and biochemical characterisation of a novel glutamate decarboxylase from rice bran. Journal of the science of food and agriculture 20100430
Quantitative expression analysis and prognostic significance of L-DOPA decarboxylase in colorectal adenocarcinoma. British journal of cancer 20100427
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. The Journal of biological chemistry 20100423
A two-step process controls the formation of the bienzyme cysteine synthase complex. The Journal of biological chemistry 20100423
Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase. The Journal of biological chemistry 20100416
Chiral discrimination among aminotransferases: inactivation by 4-amino-4,5-dihydrothiophenecarboxylic acid. Biochemistry 20100413
DFT studies on Schiff base formation of vitamin B6 analogues. Reaction between a pyridoxamine-analogue and carbonyl compounds. The journal of physical chemistry. A 20100408
Characterization of two isotypes of l-threonine dehydratase from Entamoeba histolytica. Molecular and biochemical parasitology 20100401
Vitamin B6: Killing two birds with one stone? Phytochemistry 20100401
Auxin biosynthesis inhibitors, identified by a genomics-based approach, provide insights into auxin biosynthesis. Plant & cell physiology 20100401
Esmond E. Snell--the pathfinder of B vitamins and cofactors. Journal of biochemistry 20100401
Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach. Journal of bioenergetics and biomembranes 20100401
An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. PLoS biology 20100401
Antioxidant and hepatoprotective effects of the methanol extract of the leaves of Satureja macrostema. Pharmacognosy magazine 20100401
Protective effects of quercetin on liver injury induced by ethanol. Pharmacognosy magazine 20100401
Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies. JAMA 20100317
Mutagenesis studies of human cystathionine beta-synthase: residues important for heme binding and substrate interactions. Protein and peptide letters 20100301
Lack of sustained response to teriparatide in a patient with adult hypophosphatasia. The Journal of clinical endocrinology and metabolism 20100301
Association of pyridoxal kinase and Parkinson disease. Annals of neurology 20100301
The PDXK rs2010795 variant is not associated with Parkinson disease in Italy. Annals of neurology 20100301
Physiological role of alkaline phosphatase explored in hypophosphatasia. Annals of the New York Academy of Sciences 20100301
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production. Journal of molecular biology 20100226
Chemoenzymatic synthesis of 1-deaza-pyridoxal 5'-phosphate. Bioorganic & medicinal chemistry letters 20100215
Tuning of the charge in octahedral ferric complexes based on pyridoxal-N-substituted thiosemicarbazone ligands. Dalton transactions (Cambridge, England : 2003) 20100214
Newly mutated putative-aminotransferase in nonpungent pepper (Capsicum annuum) results in biosynthesis of capsinoids, capsaicinoid analogues. Journal of agricultural and food chemistry 20100210
Platelets in defense against bacterial pathogens. Cellular and molecular life sciences : CMLS 20100201
Serine 254 enhances an induced fit mechanism in murine 5-aminolevulinate synthase. The Journal of biological chemistry 20100129
IscS functions as a primary sulfur-donating enzyme by interacting specifically with MoeB and MoaD in the biosynthesis of molybdopterin in Escherichia coli. The Journal of biological chemistry 20100122
Internal proton transfer in the external pyridoxal 5'-phosphate Schiff base in dopa decarboxylase. Biochemistry 20100112
A nanosensory device fabricated on a liposome for detection of chemical signals. Biotechnology and bioengineering 20100101
Vitamin B6 metabolism in chronic kidney disease--relation to transsulfuration, advanced glycation and cardiovascular disease. Nephron. Clinical practice 20100101
Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm). The Journal of biological chemistry 20100101
Ginkgo biloba and ginkgotoxin. Journal of natural products 20100101
Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100101
Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS genetics 20100101
Orthophosphate binding at the dimer interface of Corynebacterium callunae starch phosphorylase: mutational analysis of its role for activity and stability of the enzyme. BMC biochemistry 20100101
Automatic assignment of EC numbers. PLoS computational biology 20100101
Lipophilic aroylhydrazone chelator HNTMB and its multiple effects on ovarian cancer cells. BMC cancer 20100101
The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader. PloS one 20100101
Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons. PloS one 20100101
A mutation in the cytosolic O-acetylserine (thiol) lyase induces a genome-dependent early leaf death phenotype in Arabidopsis. BMC plant biology 20100101
Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study. Nutrition journal 20100101
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. PloS one 20100101
Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity. Bioinorganic chemistry and applications 20100101
Effect of lipopenic and hypotensive treatment on homocysteine levels in type 2 diabetics. Vascular health and risk management 20100101
A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes. Genome biology 20100101
[Immunomodulating activity of chitosan derivatives with salicylic acid and its fragments]. Prikladnaia biokhimiia i mikrobiologiia 20100101
Adsorption and quantum chemical studies on the inhibition potentials of some thiosemicarbazides for the corrosion of mild steel in acidic medium. International journal of molecular sciences 20100101
Development of simultaneous enzymatic assay method for all six individual vitamin B6 forms and pyridoxine-beta-glucoside. Journal of nutritional science and vitaminology 20100101
Association of blood lead (Pb) and plasma homocysteine: a cross sectional survey in Karachi, Pakistan. PloS one 20100101
Decreased carbohydrate metabolism enzyme activities in the glaucomatous trabecular meshwork. Molecular vision 20100101
Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin Ligase. Bioinorganic chemistry and applications 20100101
Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. PloS one 20100101
Pharmacological characterization of GABAA receptors in taurine-fed mice. Journal of biomedical science 20100101
Genetic code mutations: the breaking of a three billion year invariance. PloS one 20100101
Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. PloS one 20100101
Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2. PloS one 20100101
Antitubercular drug poisoning in a pregnant woman. Indian journal of anaesthesia 20100101
Iron-sulfur world in aerobic and hyperthermoacidophilic archaea Sulfolobus. Archaea (Vancouver, B.C.) 20100101
Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia. Frontiers in neuroanatomy 20100101
An improved, high-quality draft genome sequence of the Germination-Arrest Factor-producing Pseudomonas fluorescens WH6. BMC genomics 20100101
Prevention of mutation, cancer, and other age-associated diseases by optimizing micronutrient intake. Journal of nucleic acids 20100101
Boolean versus ranked querying for biomedical systematic reviews. BMC medical informatics and decision making 20100101
Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models. BMC neuroscience 20100101
Anti-bacterial activity of intermittent preventive treatment of malaria in pregnancy: comparative in vitro study of sulphadoxine-pyrimethamine, mefloquine, and azithromycin. Malaria journal 20100101
Identification, Cloning, and Characterization of l-Phenylserine Dehydrogenase from Pseudomonas syringae NK-15. Enzyme research 20100101
Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. PloS one 20100101
Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis. Molecular systems biology 20100101
Metabolism gets lucky. Molecular systems biology 20100101
Mechanistic and functional versatility of radical SAM enzymes. F1000 biology reports 20100101
Improvement of cutaneous sensitivity in diabetic peripheral neuropathy with combination L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate. Reviews in neurological diseases 20100101
Efficacy and safety of livwin (polyherbal formulation) in patients with acute viral hepatitis: A randomized double-blind placebo-controlled clinical trial. International journal of Ayurveda research 20100101
Kinetic analysis of cysteine desulfurase CD0387 from Synechocystis sp. PCC 6803: formation of the persulfide intermediate. Biochemistry 20091222
Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase. Biochemistry 20091222
Functional characterization of intracellular Dictyostelium discoideum P2X receptors. The Journal of biological chemistry 20091211
Initial characterization of a recombinant kynureninase from Trypanosoma cruzi identified from an EST database. Gene 20091201
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Human molecular genetics 20091201
Characterization of L-cysteine desulfhydrase from Prevotella intermedia. Oral microbiology and immunology 20091201
Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. Annals of neurology 20091201
Structure of putative 4-amino-4-deoxychorismate lyase from Thermus thermophilus HB8. Acta crystallographica. Section F, Structural biology and crystallization communications 20091201
Influence of pyridoxylidene aminoguanidine on biomarkers of the oxidative stress and selected metabolic parameters of rats with diabetes mellitus. General physiology and biophysics 20091201
Mutation of His465 alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity toward more alkaline pH. The Journal of biological chemistry 20091113
Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder. The Journal of biological chemistry 20091106
Substituent effects on the thermodynamic stability of imines formed from glycine and aromatic aldehydes: implications for the catalytic activity of pyridoxal-5'-phosphate. Journal of the American Chemical Society 20091104
Catalytic and ligand-binding characteristics of Plasmodium falciparum serine hydroxymethyltransferase. Molecular and biochemical parasitology 20091101
Glycosylation differences contribute to distinct catalytic properties among bone alkaline phosphatase isoforms. Bone 20091101
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatric research 20091101
The 1.9 A structure of the branched-chain amino-acid transaminase (IlvE) from Mycobacterium tuberculosis. Acta crystallographica. Section F, Structural biology and crystallization communications 20091101
Identification of potential DREB2C targets in Arabidopsis thaliana plants overexpressing DREB2C using proteomic analysis. Molecules and cells 20091031
Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum. Journal of biochemistry 20091001
Pyridoxal 5'-phosphate: electrophilic catalyst extraordinaire. Current opinion in chemical biology 20091001
Application of the high-performance liquid chromatography method with coulometric detection for determination of vitamin B(6) in human plasma and serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Serum folate is a reliable indicator of hyperhomocysteinemia and borderline hyperhomocysteinemia in young adults. Nutrition research (New York, N.Y.) 20091001
[On the modified process of human hemoglobin based blood substitutes]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20091001
Chemical and functional aspects of posttranslational modification of proteins. Acta naturae 20091001
Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. The Journal of biological chemistry 20090918
Heme regulation of human cystathionine beta-synthase activity: insights from fluorescence and Raman spectroscopy. Journal of the American Chemical Society 20090909
Vitamins in the monkey brain: An immunocytochemical study. Journal of chemical neuroanatomy 20090901
Arg-85 and Thr-430 in murine 5-aminolevulinate synthase coordinate acyl-CoA-binding and contribute to substrate specificity. Protein science : a publication of the Protein Society 20090901
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death. British journal of cancer 20090901
{4-[(Carbamimidoylhydrazono)methyl-kappa2N1,N4]-5-hydroxymethyl-2-methylpyridinium-3-olate-kappaO}(methanol-kappaO)copper(II) dinitrate. Acta crystallographica. Section C, Crystal structure communications 20090901
Pyridoxal 5'-phosphate binding in lysine-modified PAMAM dendrimers: a biomimetic approach. Organic letters 20090820
Multiple roles of the active site lysine of Dopa decarboxylase. Archives of biochemistry and biophysics 20090815
(31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium. Archives of biochemistry and biophysics 20090715
X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. FEBS letters 20090707
Structural insights into the alanine racemase from Enterococcus faecalis. Biochimica et biophysica acta 20090701
Inhibition of 7,8-diaminopelargonic acid aminotransferase from Mycobacterium tuberculosis by chiral and achiral anologs of its substrate: biological implications. Biochimie 20090701
Tryptophan synthase: a mine for enzymologists. Cellular and molecular life sciences : CMLS 20090701
Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes. Microbiology (Reading, England) 20090701
Catalyzing racemizations in the absence of a cofactor: the reaction mechanism in proline racemase. Journal of the American Chemical Society 20090624
Two site-directed mutations are required for the conversion of a sugar dehydratase into an aminotransferase. Biochemistry 20090616
Multifunctional role of His159in the catalytic reaction of serine palmitoyltransferase. The Journal of biological chemistry 20090605
Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of postinfectious bowel disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090601
Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing. Clinical biochemistry 20090601
Characterization of the S289A,D mutants of yeast cystathionine beta-synthase. Biochimica et biophysica acta 20090601
From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Microbiology (Reading, England) 20090601
Vitamins, not surgery: spinal fluid testing in hemispheric epilepsy. Pediatric neurology 20090601
Investigation of residues Lys112, Glu136, His138, Gly247, Tyr248, and Asp249 in the active site of yeast cystathionine beta-synthase. Biochemistry and cell biology = Biochimie et biologie cellulaire 20090601
Involvement of P2Y receptors in pyridoxal-5'-phosphate-induced cardiac preconditioning. Fundamental & clinical pharmacology 20090601
Tryptophanase-catalyzed L-tryptophan synthesis from D-serine in the presence of diammonium hydrogen phosphate. International journal of molecular sciences 20090601
Attenuating effect of melatonin on pyridoxal-stimulated release of adrenomedullary catecholamines in the rat. Life sciences 20090508
Off-target decoding of a multitarget kinase inhibitor by chemical proteomics. Chembiochem : a European journal of chemical biology 20090504
Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus. Proteins 20090501
Gene cloning and expression of pyridoxal 5'-phosphate-dependent L-threo-3-hydroxyaspartate dehydratase from Pseudomonas sp. T62, and characterization of the recombinant enzyme. Journal of biochemistry 20090501
A new perspective on the treatment of aromatic L-amino acid decarboxylase deficiency. Molecular genetics and metabolism 20090501
A simplified protein precipitation and filtration procedure for determining serum vitamin B6 by high-performance liquid chromatography. Analytical biochemistry 20090501
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20090501
New treatment paradigms in neonatal metabolic epilepsies. Journal of inherited metabolic disease 20090401
Prospective study of plasma vitamin B6 and risk of colorectal cancer in men. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090401
Cancer incidence among pesticide applicators exposed to permethrin in the Agricultural Health Study. Environmental health perspectives 20090401
Enhanced pyridoxal 5'-phosphate synthetic enzyme immunoreactivities do not contribute to GABAergic inhibition in the rat hippocampus following pilocarpine-induced status epilepticus. Neuroscience 20090331
Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation. The Journal of biological chemistry 20090327
Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase. Biochemical and biophysical research communications 20090327
Intersubunit cross-talk in pyridoxal 5'-phosphate synthase, coordinated by the C terminus of the synthase subunit. The Journal of biological chemistry 20090320
Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding. The Biochemical journal 20090315
A PLP-dependent polyketide chain releasing mechanism in the biosynthesis of mycotoxin fumonisins in Fusarium verticillioides. Journal of the American Chemical Society 20090311
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. Journal of proteome research 20090306
Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases). Purinergic signalling 20090301
Simple sequence repeats in Haemophilus influenzae. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090301
Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women. The Journal of nutrition 20090301
Heterologous expression analyses of rice OsCAS in Arabidopsis and in yeast provide evidence for its roles in cyanide detoxification rather than in cysteine synthesis in vivo. Journal of experimental botany 20090301
Structures of alternatively spliced isoforms of human ketohexokinase. Acta crystallographica. Section D, Biological crystallography 20090301
Identification and molecular characterization of tryptophanase encoded by tnaA in Porphyromonas gingivalis. Microbiology (Reading, England) 20090301
Characterization of endogenous pyridoxal 5'-phosphate-dependent alanine racemase from Bacillus pseudofirmus OF4. Journal of bioscience and bioengineering 20090301
Influence of vitamins and osmolites on growth and bacteriocin production by Lactobacillus salivarius CRL 1328 in a chemically defined medium. Canadian journal of microbiology 20090301
Effect of pyridoxamine on acrylamide formation in a glucose/asparagine model system. Journal of agricultural and food chemistry 20090211
The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae. Biochemistry 20090210
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme. Proteins 20090201
Ru(III)-catalyzed oxidation of pyridoxine and albuterol in pharmaceuticals. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090201
Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular ornithine decarboxylase and cell proliferation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090201
Coronary response to diadenosine pentaphosphate after ischaemia-reperfusion in the isolated rat heart. Cardiovascular research 20090201
Molecular characterization of alanine racemase in the Kuruma prawn Marsupenaeus japonicus. Journal of biochemistry 20090201
Biochemical characterization of alanine racemase--a spore protein produced by Bacillus anthracis. BMB reports 20090131
[Hypophosphatasia: new therapeutic approaches]. Medicina clinica 20090131
HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115
Pyridoxine 5'-phosphate oxidase, not pyridoxal kinase, involves in long-term potentiation induction in the rat dentate gyrus. Hippocampus 20090101
Expression of enzymatically active L-DOPA decarboxylase in human peripheral leukocytes. Blood cells, molecules & diseases 20090101
Serine palmitoyltransferase, the first step enzyme in sphingolipid biosynthesis, is involved in nonhost resistance. Molecular plant-microbe interactions : MPMI 20090101
Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. PloS one 20090101
Use of folding modulators to improve heterologous protein production in Escherichia coli. Microbial cell factories 20090101
The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. PloS one 20090101
Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum. PloS one 20090101
The endogenous production of hydrogen sulphide in intrauterine tissues. Reproductive biology and endocrinology : RB&E 20090101
Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis. PloS one 20090101
Attenuating action of taurine and labetalol on cardiovascular alterations by pyridoxal-isoproterenol, a vitamin-drug interaction with cardiopathologic significance. Advances in experimental medicine and biology 20090101
Reconstruction of metabolic pathways for the cattle genome. BMC systems biology 20090101
Surgical inflammation: a pathophysiological rainbow. Journal of translational medicine 20090101
Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC). Cancer cell international 20090101
The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism. PloS one 20090101
Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women. BMC cancer 20090101
Release of 11-cis-retinal from cellular retinaldehyde-binding protein by acidic lipids. Molecular vision 20090101
Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1. PloS one 20090101
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care. Critical care (London, England) 20090101
Primary Structure Revision and Active Site Mapping of E. Coli Isoleucyl-tRNA Synthetase by Means of Maldi Mass Spectrometry. The open biochemistry journal 20090101
Hair sheep blood, citrated or defibrinated, fulfills all requirements of blood agar for diagnostic microbiology laboratory tests. PloS one 20090101
A conserved ethylene biosynthesis enzyme leads to andromonoecy in two cucumis species. PloS one 20090101
Adherence to the Mediterranean diet moderates the association of aminotransferases with the prevalence of the metabolic syndrome; the ATTICA study. Nutrition & metabolism 20090101
The cellular prion protein interacts with the tissue non-specific alkaline phosphatase in membrane microdomains of bioaminergic neuronal cells. PloS one 20090101
Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames). BMC structural biology 20090101
The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families. BMC bioinformatics 20090101
Comparative analyses of genotype dependent expressed sequence tags and stress-responsive transcriptome of chickpea wilt illustrate predicted and unexpected genes and novel regulators of plant immunity. BMC genomics 20090101
Conformational changes and loose packing promote E. coli Tryptophanase cold lability. BMC structural biology 20090101
Partially-supervised protein subclass discovery with simultaneous annotation of functional residues. BMC structural biology 20090101
Edgetic perturbation models of human inherited disorders. Molecular systems biology 20090101
The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. PloS one 20090101
Vitamin B6 deficient plants display increased sensitivity to high light and photo-oxidative stress. BMC plant biology 20090101
Pharmacokinetic comparison of a delayed-release combination of doxylamine succinate and pyridoxine hydrocholoride (Diclectin) and oral solutions of these drugs in healthy women of childbearing age. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20090101
Evolution by leaps: gene duplication in bacteria. Biology direct 20090101
Sulfur metabolism actively promotes initiation of cell division in yeast. PloS one 20090101
Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress. Nutrition research and practice 20090101
A review on laboratory liver function tests. The Pan African medical journal 20090101
Teriparatide treatment in adult hypophosphatasia in a patient exposed to bisphosphonate: a case report. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 20090101
Alanine-dependent reactions of 5'-deoxypyridoxal in water. Bioorganic chemistry 20081201
B-vitamins, homocysteine and gene polymorphism in adults with fasting or post-methionine loading hyperhomocysteinemia. European journal of nutrition 20081201
The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate. Journal of bioenergetics and biomembranes 20081201
Formation of a silicon-containing macrocycle with a pyridoxalimine Schiff base ligand. Acta crystallographica. Section C, Crystal structure communications 20081201
Expression analysis of a novel pyridoxal kinase messenger RNA splice variant, PKL, in oil rape suffering abiotic stress and phytohormones. Acta biochimica et biophysica Sinica 20081201
Anticancer alkaloid lamellarins inhibit protein kinases. Marine drugs 20081201
A novel 4-oxo-2(E)-nonenal-derived modification to angiotensin II: oxidative decarboxylation of N-terminal aspartic acid. Chemical research in toxicology 20081201
Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria. The Journal of biological chemistry 20081114
In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. The Journal of biological chemistry 20081107
Cloning of the gene encoding alpha-methylserine hydroxymethyltransferase from Aminobacter sp. AJ110403 and Ensifer sp. AJ110404 and characterization of the recombinant enzyme. Bioscience, biotechnology, and biochemistry 20081101
Synthesis of 4-pyridoxolactone from pyridoxine using a combination of transformed Escherichia coli cells. Journal of bioscience and bioengineering 20081101
Insights into the catalytic mechanism of tyrosine phenol-lyase from X-ray structures of quinonoid intermediates. The Journal of biological chemistry 20081024
A quantum mechanical/molecular mechanical study on the catalysis of the pyridoxal 5'-phosphate-dependent enzyme L-serine dehydratase. The journal of physical chemistry. B 20081016
NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers. Biochimica et biophysica acta 20081001
Expression analysis and clinical utility of L-Dopa decarboxylase (DDC) in prostate cancer. Clinical biochemistry 20081001
Analysis of a horizontally transferred pathway involved in vitamin B6 biosynthesis from the soybean cyst nematode Heterodera glycines. Molecular biology and evolution 20081001
Tryptophan synthase, an allosteric molecular factory. Current opinion in chemical biology 20081001
Comparative survey of putrescine production from agmatine deamination in different bacteria. Food microbiology 20081001
Gene cloning of alpha-methylserine aldolase from Variovorax paradoxus and purification and characterization of the recombinant enzyme. Bioscience, biotechnology, and biochemistry 20081001
Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis. Biochemistry 20080930
Crenarchaeal arginine decarboxylase evolved from an S-adenosylmethionine decarboxylase enzyme. The Journal of biological chemistry 20080919
Optimization of a biomimetic transamination reaction. Journal of the American Chemical Society 20080903
Theoretical studies on pyridoxal 5'-phosphate-dependent transamination of alpha-amino acids. Journal of computational chemistry 20080901
Characterization of pyridoxal 5'- phosphate-binding domain and folding intermediate of Bacillus subtilis serine hydroxymethyltransferase: an autonomous folding domain. Journal of biochemistry 20080901
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis. Biochimica et biophysica acta 20080901
Bovine viral diarrhea viruses differentially alter the expression of the protein kinases and related proteins affecting the development of infection and anti-viral mechanisms in bovine monocytes. Biochimica et biophysica acta 20080901
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage. The FEBS journal 20080901
Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations. Bioscience, biotechnology, and biochemistry 20080901
N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine. Molecular cancer therapeutics 20080901
Pyridyl derivatives of benzaldehyde as potential antisickling agents. Chemistry & biodiversity 20080901
Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction. Drug metabolism and disposition: the biological fate of chemicals 20080801
Biodiversity of sphingoid bases ('sphingosines') and related amino alcohols. Journal of lipid research 20080801
The catalytic intermediate stabilized by a 'down' active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis. The Journal of biological chemistry 20080725
Insights into the mechanism of oxidative deamination catalyzed by DOPA decarboxylase. Biochemistry 20080708
Extrinsic fluorescent dyes as tools for protein characterization. Pharmaceutical research 20080701
13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase. Nature chemical biology 20080701
D-amino acids in the brain: structure and function of pyridoxal phosphate-dependent amino acid racemases. The FEBS journal 20080701
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080701
The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule. The Journal of biological chemistry 20080627
PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099. Biochemistry 20080610
Investigation of the stability of aromatic hydrazones in plasma and related biological material. Journal of pharmaceutical and biomedical analysis 20080609
Enzyme replacement therapy for murine hypophosphatasia. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080601
Biosynthesis of sphinganine-analog mycotoxins. Journal of industrial microbiology & biotechnology 20080601
Pyridoxal 5'-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients. Molecular genetics and metabolism 20080601
Pyridoxine induced neuropathy by subcutaneous administration in dogs. Journal of veterinary science 20080601
Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum. Acta crystallographica. Section D, Biological crystallography 20080601
Extracellular 5-aminolevulinic acid production by Escherichia coli containing the Rhodopseudomonas palustris KUGB306 hemA gene. Journal of microbiology and biotechnology 20080601
Supplementing vitamin B6 to a low vitamin B6 diet exaggerates UVB-induced skin tumorigenesis in DMBA-treated hairless mice. Journal of nutritional science and vitaminology 20080601
Human brain pyridoxal-5'-phosphate phosphatase (PLPP):protein transduction of PEP-1-PLPP into PC12 cells. BMB reports 20080531
Rapid photodynamics of vitamin B6 coenzyme pyridoxal 5'-phosphate and its Schiff bases in solution. The journal of physical chemistry. B 20080508
Anticonvulsant characteristics of pyridoxyl-gamma-aminobutyrate, PL-GABA. Neuropharmacology 20080501
Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function. Protein science : a publication of the Protein Society 20080501
Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis. Acta crystallographica. Section F, Structural biology and crystallization communications 20080501
Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial. JAMA 20080416
Production of gamma-aminobutyric acid by Streptococcus salivarius subsp. thermophilus Y2 under submerged fermentation. Amino acids 20080401
Potentialities and pitfalls accompanying chemico-pharmacological strategies against endogenous electrophiles and carbonyl stress. Chemical research in toxicology 20080401
Elongation changes of exploratory and root hair systems induced by aminocyclopropane carboxylic acid and aminoethoxyvinylglycine affect nitrate uptake and BnNrt2.1 and BnNrt1.1 transporter gene expression in oilseed rape. Plant physiology 20080401
Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii. Acta crystallographica. Section D, Biological crystallography 20080401
Glycation of plasma lipoprotein lipid membrane and screening for lipid glycation inhibitor. Annals of the New York Academy of Sciences 20080401
Analysis of amadori-glycated phosphatidylethanolamine in the plasma of healthy subjects and diabetic patients by liquid chromatography-tandem mass spectrometry. Annals of the New York Academy of Sciences 20080401
Acceleration of the substrate Calpha deprotonation by an analogue of the second substrate palmitoyl-CoA in Serine Palmitoyltransferase. The Journal of biological chemistry 20080321
Calcium- and salt-stress signaling in plants: shedding light on SOS pathway. Archives of biochemistry and biophysics 20080315
Preventing cell death induced by carbonyl stress, oxidative stress or mitochondrial toxins with vitamin B anti-AGE agents. Molecular nutrition & food research 20080301
Inhibitory and structural studies of novel coenzyme-substrate analogs of human histidine decarboxylase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080301
Metabolism of halophilic archaea. Extremophiles : life under extreme conditions 20080301
Treatment of adult hypophosphatasia with teriparatide. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20080301
Plasma pyridoxal 5'-phosphate and high-sensitivity C-reactive protein are independently associated with an increased risk of coronary artery disease. Nutrition (Burbank, Los Angeles County, Calif.) 20080301
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. Journal of the American Dietetic Association 20080301
GDP-4-keto-6-deoxy-D-mannose 3-dehydratase, accommodating a sugar substrate in the active site. The Journal of biological chemistry 20080215
Glycine enolates: the effect of formation of iminium ions to simple ketones on alpha-amino carbon acidity and a comparison with pyridoxal iminium ions. Journal of the American Chemical Society 20080213
Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry 20080212
Crystal structure of human kynurenine aminotransferase II. The Journal of biological chemistry 20080208
Structure of biosynthetic N-acetylornithine aminotransferase from Salmonella typhimurium: studies on substrate specificity and inhibitor binding. Proteins 20080201
A novel class of advanced glycation inhibitors ameliorates renal and cardiovascular damage in experimental rat models. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201
Polycystic kidney diseases: from molecular discoveries to targeted therapeutic strategies. Cellular and molecular life sciences : CMLS 20080201
Filling the gap of intracellular dephosphorylation in the Plasmodium falciparum vitamin B1 biosynthesis. Molecular and biochemical parasitology 20080201
An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites. Molecular microbiology 20080201
Determination of individual vitamin B(6) compounds based on enzymatic conversion to 4-pyridoxolactone. Journal of nutritional science and vitaminology 20080201
Therapeutical approach to plasma homocysteine and cardiovascular risk reduction. Therapeutics and clinical risk management 20080201
A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae. The Biochemical journal 20080115
The first steps. The attack on the carbonyl carbon of pyridoxal cofactor in pyridoxal-dependent enzymes. Bioorganic & medicinal chemistry letters 20080115
Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099. The Journal of biological chemistry 20080111
Study of neutral Fe(III) complexes of pyridoxal-N-substituted thiosemicarbazone with desolvation-induced spin-state transformation above room temperature. Inorganic chemistry 20080107
D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia. Journal of biochemistry 20080101
Physiological roles of the beta-substituted alanine synthase gene family in Arabidopsis. Plant physiology 20080101
Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme. PLoS neglected tropical diseases 20080101
Overexpression, crystallization, and preliminary X-ray crystallographic analysis of the alanine racemase from Enterococcus faecalis v583. Journal of microbiology and biotechnology 20080101
Trapping of a chromophoric intermediate in the Pdx1-catalyzed biosynthesis of pyridoxal 5'-phosphate. Angewandte Chemie (International ed. in English) 20080101
Pyridoxal isonicotinoyl hydrazone (PIH) and its analogs as protectants against anthracycline-induced cardiotoxicity. Hemoglobin 20080101
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli. Protein and peptide letters 20080101
A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. Molecular systems biology 20080101
The assembly of the plasmodial PLP synthase complex follows a defined course. PloS one 20080101
Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis. BMC plant biology 20080101
The SU.FOL.OM3 Study: a secondary prevention trial testing the impact of supplementation with folate and B-vitamins and/or Omega-3 PUFA on fatal and non fatal cardiovascular events, design, methods and participants characteristics. Trials 20080101
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. BMC biochemistry 20080101
Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery. Scandinavian journal of gastroenterology 20080101
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes. Asia Pacific journal of clinical nutrition 20080101
PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation. PloS one 20080101
Low plasma pyridoxal 5'-phosphate concentration and MTHFR 677C-->T genotypes are associated with increased risk of hypertension. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20080101
Pyridoxal plasma level in schizophrenic and schizoaffective patients with and without tardive dyskinesia. Clinical neuropharmacology 20080101
Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors. PloS one 20080101
Microarray analysis of toxicogenomic effects of ortho-phenylphenol in Staphylococcus aureus. BMC genomics 20080101
Splice-mediated Variants of Proteins (SpliVaP) - data and characterization of changes in signatures among protein isoforms due to alternative splicing. BMC genomics 20080101
Targeting aspartate aminotransferase in breast cancer. Breast cancer research : BCR 20080101
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome biology 20080101
Development of highly sensitive extractive spectrophotometric determination of nickel(II) in medicinal leaves, soil, industrial effluents and standard alloy samples using pyridoxal-4-phenyl-3-thiosemicarbazone. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20080101
Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation. PloS one 20080101
The role of vitamins and minerals in psychiatry. Integrative medicine insights 20080101
Is gene activity in plant cells affected by UMTS-irradiation? A whole genome approach. Advances and applications in bioinformatics and chemistry : AABC 20080101
Enantiomers of 4-amino-3-fluorobutanoic acid as substrates for gamma-aminobutyric acid aminotransferase. Conformational probes for GABA binding. Biochemistry 20071204
Expression, purification and characterization of a cysteine desulfurase, IscS, from Acidithiobacillus ferrooxidans. Biotechnology letters 20071201
Association between PNPO and schizophrenia in the Japanese population. Schizophrenia research 20071201
New developments in selenium biochemistry: selenocysteine biosynthesis in eukaryotes and archaea. Biological trace element research 20071201
The first thermophilic alpha-oxoamine synthase family enzyme that has activities of 2-amino-3-ketobutyrate CoA ligase and 7-keto-8-aminopelargonic acid synthase: cloning and overexpression of the gene from an extreme thermophile, Thermus thermophilus, and characterization of its gene product. Bioscience, biotechnology, and biochemistry 20071201
Patterns and implications of gene gain and loss in the evolution of Prochlorococcus. PLoS genetics 20071201
Study on complex formation of biologically active pyridine derivatives with cyclodextrins by capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20071130
Reversed-phase high-performance liquid chromatography method with coulometric electrochemical and ultraviolet detection for the quantification of vitamins B(1) (thiamine), B(6) (pyridoxamine, pyridoxal and pyridoxine) and B(12) in animal and plant foods. Journal of chromatography. A 20071130
Gene identification and structural characterization of the pyridoxal 5'-phosphate degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from mesorhizobium loti MAFF303099. Biochemistry 20071127
Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium. Biochemistry 20071113
Biochemical characterization, homology modeling and docking studies of ornithine delta-aminotransferase--an important enzyme in proline biosynthesis of plants. Journal of molecular graphics & modelling 20071101
Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway. Plant physiology 20071101
B vitamin plasma levels and the risk of ischemic stroke and transient ischemic attack in a German cohort. Stroke 20071101
Capillary electrophoretic screening for the inhibition of homocysteine thiolactone-induced protein oligomerization. Analytical chemistry 20071101
4-[(2-Hydroxyethyl)iminomethyl]-5-hydroxymethyl-2-methylpyridin-3-ol. Acta crystallographica. Section C, Crystal structure communications 20071101
Spectrophotometric determination of ternary mixtures of thiamin, riboflavin and pyridoxal in pharmaceutical and human plasma by least-squares support vector machines. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20071101
Methods for measuring cysteine S-conjugate β-lyase activity. Current protocols in toxicology 20071101
Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein science : a publication of the Protein Society 20071001
Probing the active site of Corynebacterium callunae starch phosphorylase through the characterization of wild-type and His334-->Gly mutant enzymes. The FEBS journal 20071001
Two independent routes of de novo vitamin B6 biosynthesis: not that different after all. The Biochemical journal 20071001
Luminescence and structural properties of lanthanide complexes of Schiff bases derived from pyridoxal and amino acids. Dalton transactions (Cambridge, England : 2003) 20070928
Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals 'a tale of two mechanisms'. Biochemistry 20070918
Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070901
The aspartate aminotransferase family in conifers: biochemical analysis of a prokaryotic-type enzyme from maritime pine. Tree physiology 20070901
Hydrogen sulphide: a novel endogenous gasotransmitter facilitates erectile function. The journal of sexual medicine 20070901
The daily timing of gene expression and physiology in mammals. Dialogues in clinical neuroscience 20070901
Transient kinetic studies support refinements to the chemical and kinetic mechanisms of aminolevulinate synthase. The Journal of biological chemistry 20070810
Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
Chemical chaperone rescue of mutant human cystathionine beta-synthase. Molecular genetics and metabolism 20070801
Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory. The FEBS journal 20070801
A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS genetics 20070801
Bombyx mori pyridoxal kinase cDNA cloning and enzymatic characterization. Journal of genetics and genomics = Yi chuan xue bao 20070801
Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes. Biochemistry 20070717
Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands. Biochemistry 20070703
Vitamin B biosynthesis in plants. Phytochemistry 20070701
Time course of changes in pyridoxal 5'-phosphate (vitamin B6 active form) and its neuroprotection in experimental ischemic damage. Experimental neurology 20070701
Synthesis, spectroscopic and X-ray characterization of a copper(II) complex with the Schiff base derived from pyridoxal and aminoguanidine: NMR spectral studies of the ligand. Journal of inorganic biochemistry 20070701
Purification and partial characterization of N-hydroxy-l-phenylalanine decarboxylase/oxidase from Bacillus sp. strain OxB-1, an enzyme involved in aldoxime biosynthesis in the 'aldoxime-nitrile pathway'. Biochimica et biophysica acta 20070701
Synthesis of 4-hydroxyisoleucine by the aldolase-transaminase coupling reaction and basic characterization of the aldolase from Arthrobacter simplex AKU 626. Bioscience, biotechnology, and biochemistry 20070701
Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus. Journal of molecular biology 20070629
The mechanism of addition of pyridoxal 5'-phosphate to Escherichia coli apo-serine hydroxymethyltransferase. The Biochemical journal 20070615
Biomass in the manufacture of industrial products--the use of proteins and amino acids. Applied microbiology and biotechnology 20070601
Pyridoxine-responsive seizures as the first symptom of infantile hypophosphatasia caused by two novel missense mutations (c.677T>C, p.M226T; c.1112C>T, p.T371I) of the tissue-nonspecific alkaline phosphatase gene. Bone 20070601
Functional analysis of PDX2 from Arabidopsis, a glutaminase involved in vitamin B6 biosynthesis. Plant physiology 20070601
Serine racemases from barley, Hordeum vulgare L., and other plant species represent a distinct eukaryotic group: gene cloning and recombinant protein characterization. Phytochemistry 20070601
Purification, crystallization and preliminary X-ray crystallographic analysis of branched-chain aminotransferase from Deinococcus radiodurans. Acta crystallographica. Section F, Structural biology and crystallization communications 20070601
Histidine 282 in 5-aminolevulinate synthase affects substrate binding and catalysis. Biochemistry 20070522
A novel DNA modification by sulfur: DndA is a NifS-like cysteine desulfurase capable of assembling DndC as an iron-sulfur cluster protein in Streptomyces lividans. Biochemistry 20070522
Future of toxicology--iron chelators and differing modes of action and toxicity: the changing face of iron chelation therapy. Chemical research in toxicology 20070501
Thermodynamic characterization of the protein-protein interaction in the heteromeric Bacillus subtilis pyridoxalphosphate synthase. Biochemistry 20070501
Structural and chemical profiling of the human cytosolic sulfotransferases. PLoS biology 20070501
Repression of anti-apoptotic genes via AP-1 as a mechanism of apoptosis induction in ventricular cardiomyocytes. Pflugers Archiv : European journal of physiology 20070401
Molecular modelling studies on the interactions of human DNA topoisomerase IB with pyridoxal-compounds. Biochimie 20070401
Vitamin B6 suppresses apoptosis of NM-1 bovine endothelial cells induced by homocysteine and copper. Biochimica et biophysica acta 20070401
Adult hypophosphatasia treated with teriparatide. The Journal of clinical endocrinology and metabolism 20070401
A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast. The FEBS journal 20070401
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nature structural & molecular biology 20070401
Simultaneous fluorometric resolution of pyridoxal, pyridoxamine and 4-pyridoxic acid using chemometric methods. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070401
Covalent catalysis by pyridoxal: evaluation of the effect of the cofactor on the carbon acidity of glycine. Journal of the American Chemical Society 20070314
Crystal structure of Homo sapiens kynureninase. Biochemistry 20070313
Reaction mechanism of pyridoxal 5'-phosphate synthase. Detection of an enzyme-bound chromophoric intermediate. The Journal of biological chemistry 20070302
Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of toxicology 20070301
Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana. FEBS letters 20070206
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway. Plant & cell physiology 20070201
Pyridoxal 5'-phosphate may be curative in early-onset epileptic encephalopathy. Journal of inherited metabolic disease 20070201
The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo biloba. The FEBS journal 20070201
Crystallization and preliminary X-ray diffraction analysis of omega-amino acid:pyruvate transaminase from Chromobacterium violaceum. Acta crystallographica. Section F, Structural biology and crystallization communications 20070201
Air pollution, smoking, and plasma homocysteine. Environmental health perspectives 20070201
Alanine racemase from Helicobacter pylori NCTC 11637: purification, characterization and gene cloning. Life sciences 20070130
Identification of functional subclasses in the DJ-1 superfamily proteins. PLoS computational biology 20070126
A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days. British journal of cancer 20070115
Alanine racemase from the acidophile Acetobacter aceti. Protein expression and purification 20070101
Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS biology 20070101
Chronic multifocal non-bacterial osteomyelitis in hypophosphatasia mimicking malignancy. BMC pediatrics 20070101
Vitamin B6 status, deficiency and its consequences--an overview. Nutricion hospitalaria 20070101
Effects of ATP on rat renal haemodynamics and excretion: role of sodium intake, nitric oxide and cytochrome P450. Acta physiologica (Oxford, England) 20070101
Enzyme-catalyzed side reactions with molecular oxygen may contribute to cell signaling and neurodegenerative diseases. Neurochemical research 20070101
Hydrogen sulfide (H2S) - the third gas of interest for pharmacologists. Pharmacological reports : PR 20070101
Alanine racemase from the green alga Chlamydomonas reinhardtii. Amino acids 20070101
Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents. Physiological research 20070101
Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents. Current medicinal chemistry 20070101
Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study. Malaria journal 20070101
Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes. Genome biology 20070101
Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions. BMC genomics 20070101
Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations. BMC genomics 20070101
Redox stress proteins are involved in adaptation response of the hyperthermoacidophilic archaeon Sulfolobus solfataricus to nickel challenge. Microbial cell factories 20070101
Novel inhibitors of glycation and AGE formation. Cell biochemistry and biophysics 20070101
GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. BMC genomics 20070101
Hypophosphatasia. Orphanet journal of rare diseases 20070101
Are we getting enough sulfur in our diet? Nutrition & metabolism 20070101
Hemoglobin-vesicles for a transfusion alternative and targeted oxygen delivery. Journal of liposome research 20070101
Characterization of Cu(II)-ACC complexes and conversion of the bound ACC into ethylene in the presence of hydrogen peroxide. detection of a brown intermediate at low temperature. Bioinorganic chemistry and applications 20070101
Crystal structures of Salmonella typhimurium biodegradative threonine deaminase and its complex with CMP provide structural insights into ligand-induced oligomerization and enzyme activation. The Journal of biological chemistry 20061222
A combined quantum mechanical and molecular mechanical study of the reaction mechanism and alpha-amino acidity in alanine racemase. Journal of the American Chemical Society 20061220
Sulfur mobilization in cyanobacteria: the catalytic mechanism of L-cystine C-S lyase (C-DES) from synechocystis. The Journal of biological chemistry 20061215
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. The Journal of biological chemistry 20061201
Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity. The Journal of pharmacology and experimental therapeutics 20061201
Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin. British journal of pharmacology 20061201
[Elevated plasma concentration of homocysteine, low level of vitamin B6, pyridoxal, and vitamin D insufficiency in patients with hip fracture: a possible explanation for detrimental cross-link pattern in bone collagen]. Clinical calcium 20061201
Dimerization and folding processes of Treponema denticola cystalysin: the role of pyridoxal 5'-phosphate. Biochemistry 20061128
Mass-spectrometrical analysis of proteins encoded on chromosome 21 in human fetal brain. Amino acids 20061101
Holo- and apo-cystalysin from Treponema denticola: two different conformations. Archives of biochemistry and biophysics 20061101
Profilin 1 obtained by proteomic analysis in all-trans retinoic acid-treated hepatocarcinoma cell lines is involved in inhibition of cell proliferation and migration. Proteomics 20061101
Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. Chemico-biological interactions 20061027
Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways. Chemico-biological interactions 20061027
Identification of structural and catalytic classes of highly conserved amino acid residues in lysine 2,3-aminomutase. Biochemistry 20061024
The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution. Journal of molecular biology 20061020
Vitamin B6 supplementation increases immune responses in critically ill patients. European journal of clinical nutrition 20061001
Expression of alr gene from Corynebacterium glutamicum ATCC 13032 in Escherichia coli and molecular characterization of the recombinant alanine racemase. Journal of biotechnology 20061001
Chelation of UO(2)(2+) by vitamin B6 complex derivatives: synthesis and characterization of [UO2(beta-pyracinide)2(H2O)] and [UO2(Pyr2en)DMSO]Cl2{Pyr2en=N,N'-ethylenebis(pyridoxylideneiminato)}. A useful modeling of assimilation of uranium by living beings. Journal of inorganic biochemistry 20061001
7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target. Characterization and inhibition studies. The FEBS journal 20061001
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of the biosynthetic N-acetylornithine aminotransferases from Salmonella typhimurium and Escherichia coli. Acta crystallographica. Section F, Structural biology and crystallization communications 20061001
Cloning, purification and preliminary crystallographic analysis of a putative pyridoxal kinase from Bacillus subtilis. Acta crystallographica. Section F, Structural biology and crystallization communications 20061001
Dietary intake of vitamin B6 and concentration of vitamin B6 in blood samples of German vegans. Public health nutrition 20060901
Claisen-type addition of glycine to a pyridoxal iminium ion in water. The Journal of organic chemistry 20060901
Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls. Calcified tissue international 20060901
Plant phenylacetaldehyde synthase is a bifunctional homotetrameric enzyme that catalyzes phenylalanine decarboxylation and oxidation. The Journal of biological chemistry 20060818
Structural basis for D-amino acid transamination by the pyridoxal 5'-phosphate-dependent catalytic antibody 15A9. The Journal of biological chemistry 20060818
How an enzyme tames reactive intermediates: positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy. Journal of the American Chemical Society 20060809
Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase. Biochemistry 20060808
Identification of a new tetrameric pyridoxal 4-dehydrogenase as the second enzyme in the degradation pathway for pyridoxine in a nitrogen-fixing symbiotic bacterium, Mesorhizobium loti. Archives of biochemistry and biophysics 20060801
The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution. Acta crystallographica. Section F, Structural biology and crystallization communications 20060801
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. Biochemistry 20060725
HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060711
cDNA cloning, expression, purification, distribution, and characterization of biologically active canine alanine aminotransferase-1. Protein expression and purification 20060701
Histamine, histidine, and growth-phase mediated regulation of the histidine decarboxylase gene in lactic acid bacteria isolated from wine. FEMS microbiology letters 20060701
Transition state stabilization and alpha-amino carbon acidity in alanine racemase. Journal of the American Chemical Society 20060628
Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions. Biochemistry 20060620
Molecular cloning, expression and characterization of pyridoxamine-pyruvate aminotransferase. The Biochemical journal 20060615
Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB. The EMBO journal 20060607
Crystal structure of human pyridoxal kinase. Journal of structural biology 20060601
The genetic basis of human erythrocyte pyridoxal kinase activity variation. Haematologica 20060601
X-ray crystallographic structures of enamine and amine Schiff bases of pyridoxal and its 1:1 hydrogen-bonded complexes with benzoic acid derivatives: evidence for coupled inter- and intramolecular proton transfer. Acta crystallographica. Section B, Structural science 20060601
Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters. PLoS biology 20060601
Overexpression, purification and crystallization of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv. Acta crystallographica. Section F, Structural biology and crystallization communications 20060601
Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. Purinergic signalling 20060601
Evolutionary relationship between initial enzymes of tetrapyrrole biosynthesis. Journal of molecular biology 20060519
Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor. Journal of lipid research 20060501
Enzymatic and biochemical properties of a novel human serine dehydratase isoform. Biochimica et biophysica acta 20060501
Alanine racemase of alfalfa seedlings (Medicago sativa L.): first evidence for the presence of an amino acid racemase in plants. Phytochemistry 20060501
Molecular and biochemical characterization of a serine racemase from Arabidopsis thaliana. Phytochemistry 20060401
New structural insights to help in the search for selective inhibitors of mammalian pyridoxal 5'-phosphate-dependent histidine decarboxylase . 4. Synthesis, metabolism and release of histamine. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401
Vitamin B6 suppresses growth of the feline mammary tumor cell line FRM. Bioscience, biotechnology, and biochemistry 20060401
Hyperphosphatasia with neurologic deficit: a pyridoxine-responsive seizure disorder? Pediatric neurology 20060401
Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors. European journal of pharmacology 20060318
L-cysteate sulpho-lyase, a widespread pyridoxal 5'-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3(T). The Biochemical journal 20060315
YZGD from Paenibacillus thiaminolyticus, a pyridoxal phosphatase of the HAD (haloacid dehalogenase) superfamily and a versatile member of the Nudix (nucleoside diphosphate x) hydrolase superfamily. The Biochemical journal 20060315
High-level expression and bulk crystallization of recombinant L-methionine gamma-lyase, an anticancer agent. Applied microbiology and biotechnology 20060301
Dissimilation of C3-sulfonates. Archives of microbiology 20060301
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6. Seizure 20060301
Mutations in antiquitin in individuals with pyridoxine-dependent seizures. Nature medicine 20060301
Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent. Cancer research 20060301
Children of Latino immigrants, 4-8 years, in rural Nebraska are adequate in vitamin B-6. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060301
Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase. The Journal of biological chemistry 20060224
Dioxo- and oxovanadium(V) complexes of thiohydrazone ONS donor ligands: synthesis, characterization, reactivity, and antiamoebic activity. Inorganic chemistry 20060206
A novel role of circadian transcription factor DBP in hippocampal plasticity. Molecular and cellular neurosciences 20060201
Ionization state of pyridoxal 5'-phosphate in D-serine dehydratase, dialkylglycine decarboxylase and tyrosine phenol-lyase and the influence of monovalent cations as inferred by 31P NMR spectroscopy. Biochimica et biophysica acta 20060201
Cloning and expression of the pyridoxal 5'-phosphate-dependent aspartate racemase gene from the bivalve mollusk Scapharca broughtonii and characterization of the recombinant enzyme. Journal of biochemistry 20060201
Cysteine S-conjugate beta-lyases. Amino acids 20060201
HPLC study on stability of pyridoxal isonicotinoyl hydrazone. Journal of pharmaceutical and biomedical analysis 20060123
Dietary forage and nonfiber carbohydrate contents influence B-vitamin intake, duodenal flow, and apparent ruminal synthesis in lactating dairy cows. Journal of dairy science 20060101
Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatella species. BMC infectious diseases 20060101
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies. Lipids in health and disease 20060101
Abnormally high plasma levels of vitamin B6 in children with autism not taking supplements compared to controls not taking supplements. Journal of alternative and complementary medicine (New York, N.Y.) 20060101
A gold standard set of mechanistically diverse enzyme superfamilies. Genome biology 20060101
[Blocking action of pyridoxal-5'-phosphate on nonadrenergic synaptic inhibition of human small intestine smooth muscle]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101
Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody. Retrovirology 20060101
Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia. Orphanet journal of rare diseases 20060101
Low pyridoxal 5'-phosphate is associated with increased risk of coronary artery disease. Nutrition (Burbank, Los Angeles County, Calif.) 20060101
Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains. BMC genomics 20060101
Occurrence and functions of free D-aspartate and its metabolizing enzymes. Chemical record (New York, N.Y.) 20060101
Exploring the pyridoxal 5'-phosphate-dependent enzymes. Chemical record (New York, N.Y.) 20060101
High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium. Microbial cell factories 20060101
[Abiotrophia and Granulicatella]. Revista Argentina de microbiologia 20060101
Taurine attenuates pyridoxal-induced adrenomedullary catecholamine release and glycogenolysis in the rat. Advances in experimental medicine and biology 20060101
Comparison of the effects of taurine with those of related sulfur-containing compounds on pyridoxal-induced adrenomedullary catecholamine release and glycogenolysis in the rat. Advances in experimental medicine and biology 20060101
Low serum alkaline phosphatase activity and pathologic fracture: case report and brief review of hypophosphatasia diagnosed in adulthood. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101
Substrate recognition by the human fatty-acid synthase. The Journal of biological chemistry 20051230
Synthesis and antimicrobial activity of 5-hydroxymethyl- 8-methyl-2-(N-arylimino)-pyrano[2,3-c]pyridine-3-(N-aryl)-carboxamides. Bioorganic & medicinal chemistry letters 20051215
Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate. Biochemistry 20051206
Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats. Drug metabolism and disposition: the biological fate of chemicals 20051201
Age-dependent changes of pyridoxal phosphate synthesizing enzymes immunoreactivities and activities in the gerbil hippocampal CA1 region. Mechanisms of ageing and development 20051201
Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein. Biochimie 20051201
Vitamin B6 suppresses NF-kappaB activation in LPS-stimulated mouse macrophages. International journal of molecular medicine 20051201
Pyridoxal phosphate inhibits the group I intron splicing. Molecular and cellular biochemistry 20051201
Purification and characterization of pyridoxine 5'-phosphate phosphatase from Sinorhizobium meliloti. Bioscience, biotechnology, and biochemistry 20051201
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana. The Journal of biological chemistry 20051118
Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate. Acta crystallographica. Section D, Biological crystallography 20051101
Differential effects of temperature and hydrostatic pressure on the formation of quinonoid intermediates from L-Trp and L-Met by H463F mutant Escherichia coli tryptophan indole-lyase. Biochemistry 20051101
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase. The FEBS journal 20051101
Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits. Human & experimental toxicology 20051101
[Determination of the catalytic structures of methyl parathion hydrolase]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20051101
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies. Biochemistry 20051025
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity. Biochemistry 20051004
Cloning of alanine racemase genes from Pseudomonas fluorescens strains and oligomerization states of gene products expressed in Escherichia coli. Journal of bioscience and bioengineering 20051001
Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans. The EMBO journal 20050921
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis. The Journal of biological chemistry 20050916
Use of chlorite to improve HPLC detection of pyridoxal 5'-phosphate. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050905
Roscovitine targets, protein kinases and pyridoxal kinase. The Journal of biological chemistry 20050902
Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. The Journal of biological chemistry 20050902
Recombinant production of serine hydroxymethyl transferase from Streptococcus thermophilus and its preliminary evaluation as a biocatalyst. Applied microbiology and biotechnology 20050901
Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats. Evidence-based complementary and alternative medicine : eCAM 20050901
Directed evolution of bacterial alanine racemases with higher expression level. Journal of bioscience and bioengineering 20050901
Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in l-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0A resolution. Journal of molecular biology 20050812
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli. The Biochemical journal 20050801
Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy. Protein science : a publication of the Protein Society 20050801
Development of an extractive spectrophotometric method for the determination of copper(II) in leafy vegetable and pharmaceutical samples using pyridoxal-4-phenyl-3-thiosemicarbazone (PPT). Journal of agricultural and food chemistry 20050713
Clinical vitamin B6 analysis: an interlaboratory comparison of pyridoxal 5'-phosphate measurements in serum. Clinical chemistry 20050701
Multianalyte quantification of vitamin B6 and B2 species in the nanomolar range in human plasma by liquid chromatography-tandem mass spectrometry. Clinical chemistry 20050701
Purification and characterization of mouse hepatic enzyme that converts selenomethionine to methylselenol by its alpha,gamma-elimination. Biological trace element research 20050701
Inhibition of glycosylation processes: the reaction between pyridoxamine and glucose. Chemistry & biodiversity 20050701
Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase. Biochimica et biophysica acta 20050615
Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry 20050614
Oxygen release from low and normal P50 Hb vesicles in transiently occluded arterioles of the hamster window model. American journal of physiology. Heart and circulatory physiology 20050601
Identification of new proteins in follicular fluid from mature human follicles by direct sample rehydration method of two-dimensional polyacrylamide gel electrophoresis. Journal of Korean medical science 20050601
Structure of Citrobacter freundii L-methionine gamma-lyase. Acta crystallographica. Section F, Structural biology and crystallization communications 20050601
Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies. Biochemistry 20050510
Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women. Journal of the National Cancer Institute 20050504
Effect of a swim training on homocysteine and cysteine levels in rats. Amino acids 20050501
An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS biology 20050501
Tat-mediated protein transduction of human brain pyridoxal kinase into PC12 cells. Biochimie 20050501
Conversion of 5-aminolevulinate synthase into a more active enzyme by linking the two subunits: spectroscopic and kinetic properties. Protein science : a publication of the Protein Society 20050501
Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme. Acta crystallographica. Section D, Biological crystallography 20050501
Investigation of systemic folate status, impact of alcohol intake and levels of DNA damage in mononuclear cells of breast cancer patients. British journal of cancer 20050425
Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine. FEBS letters 20050425
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia. The EMBO journal 20050420
Catalytic mechanism of alpha-retaining glucosyl transfer by Corynebacterium callunae starch phosphorylase: the role of histidine-334 examined through kinetic characterization of site-directed mutants. The Biochemical journal 20050415
A comparative study of various computational approaches in calculating the structure of pyridoxal 5'-phosphate (PLP)-dependent beta-lyase protein. The importance of protein environment. Journal of computational chemistry 20050415
Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase. Human molecular genetics 20050415
Effect of a Y265F mutant on the transamination-based cycloserine inactivation of alanine racemase. Biochemistry 20050412
Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase. Biochemistry 20050412
Identification of the geometric requirements for allosteric communication between the alpha- and beta-subunits of tryptophan synthase. The Journal of biological chemistry 20050408
Pyridoxine in clinical toxicology: a review. European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20050401
Homocysteine in chronic kidney disease: Effect of low protein diet and repletion with B vitamins. Kidney international 20050401
Copper(II) and cobalt(III) pyridoxal thiosemicarbazone complexes with nitroprusside as counterion: syntheses, electronic properties, and antileukemic activity. Journal of medicinal chemistry 20050310
Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor. The Journal of biological chemistry 20050304
Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits. Pharmacological research 20050301
Iron chelation therapy. Current hematology reports 20050301
Structure of Escherichia coli glutamate decarboxylase (GADalpha) in complex with glutarate at 2.05 angstroms resolution. Acta crystallographica. Section D, Biological crystallography 20050301
The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus. Chemistry & biology 20050301
Analysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparum. The Journal of biological chemistry 20050218
Vitamin B6 compounds prevent the death of yeast cells due to menadione, a reactive oxygen generator. Biochimica et biophysica acta 20050211
Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Molecular biology and evolution 20050201
Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+). Eukaryotic cell 20050201
Pyridoxal phosphate and hepatocyte growth factor prevent dialysate-induced peritoneal damage. Journal of the American Society of Nephrology : JASN 20050101
The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity. Archives of biochemistry and biophysics 20050101
Blood lead is a predictor of homocysteine levels in a population-based study of older adults. Environmental health perspectives 20050101
Nutrition education: a questionnaire for assessment and teaching. Nutrition journal 20050101
Hyper-homocysteinemia is not a main feature of juvenile uncomplicated type 1 diabetes. Journal of atherosclerosis and thrombosis 20050101
Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene. BMC genomics 20050101
A comprehensive update of the sequence and structure classification of kinases. BMC structural biology 20050101
The role of cystathionine beta-synthase in homocysteine metabolism. Antioxidants & redox signaling 20050101
Optimization of culture conditions to obtain maximal growth of penicillin-resistant Streptococcus pneumoniae. BMC microbiology 20050101
Plasma pyridoxal 5'-phosphate is a significant indicator of immune responses in the mechanically ventilated critically ill. Nutrition (Burbank, Los Angeles County, Calif.) 20050101
Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. Genome biology 20050101
Arabidopsis ETO1 specifically interacts with and negatively regulates type 2 1-aminocyclopropane-1-carboxylate synthases. BMC plant biology 20050101
Organic compatible solutes of halotolerant and halophilic microorganisms. Saline systems 20050101
Inflammation causes tissue-specific depletion of vitamin B6. Arthritis research & therapy 20050101
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis research & therapy 20050101
Biosynthesis of colitose: expression, purification, and mechanistic characterization of GDP-4-keto-6-deoxy-D-mannose-3-dehydrase (ColD) and GDP-L-colitose synthase (ColC). Biochemistry 20041228
The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum. The Journal of biological chemistry 20041210
Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol. Biochemical and biophysical research communications 20041203
Homocysteine and cardiovascular disease: interactions between nutrition, genetics and lifestyle. Canadian journal of applied physiology = Revue canadienne de physiologie appliquee 20041201
Chromatographic methods for the separation of biocompatible iron chelators from their synthetic precursors and iron chelates. Journal of separation science 20041201
Pilot study of a moderate dose multivitamin/mineral supplement for children with autistic spectrum disorder. Journal of alternative and complementary medicine (New York, N.Y.) 20041201
Anti-angiogenic effect of pyridoxal 5'-phosphate, pyridoxal and pyridoxamine on embryoid bodies derived from mouse embryonic stem cells. International journal of molecular medicine 20041101
Crystallization and preliminary X-ray analysis of pyridoxal 4-dehydrogenase, the second enzyme in degradation pathway I of pyridoxine. Acta crystallographica. Section D, Biological crystallography 20041101
Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product. The Journal of biological chemistry 20041029
Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction. Biochemistry 20041026
Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase. Biochemistry 20041019
Pyridoxal phosphatase is a novel cancer autoantigen in the central nervous system. British journal of cancer 20041018
Clinical analysis of vitamin B(6): determination of pyridoxal 5'-phosphate and 4-pyridoxic acid in human serum by reversed-phase high-performance liquid chromatography with chlorite postcolumn derivatization. Analytical biochemistry 20041015
Micellar liquid chromatography in clinical chemistry: application to the monitorization of B6 vitamins. Clinica chimica acta; international journal of clinical chemistry 20041001
The relationship between plasma and red cell concentrations of vitamins thiamine diphosphate, flavin adenine dinucleotide and pyridoxal 5-phosphate following elective knee arthroplasty. Clinical nutrition (Edinburgh, Scotland) 20041001
Mutational analysis and characterization of nocardicin C-9' epimerase. The Journal of biological chemistry 20040910
Molecular cloning, expression, and properties of an unusual aldo-keto reductase family enzyme, pyridoxal 4-dehydrogenase, that catalyzes irreversible oxidation of pyridoxal. The Journal of biological chemistry 20040903
Claisen-type addition of glycine to pyridoxal in water. Journal of the American Chemical Society 20040901
The pyridoxal kinase gene TaPdxK from wheat complements vitamin B6 synthesis-defective Escherichia coli. Journal of plant physiology 20040901
Structural and enzymatic properties of 1-aminocyclopropane-1-carboxylate deaminase homologue from Pyrococcus horikoshii. Journal of molecular biology 20040820
Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases. Protein expression and purification 20040801
Relationships between structure, function and stability for pyridoxal 5'-phosphate-dependent starch phosphorylase from Corynebacterium callunae as revealed by reversible cofactor dissociation studies. European journal of biochemistry 20040801
Hyperhomocysteinemia, pregnancy complications, and the timing of investigation. Obstetrics and gynecology 20040801
Synthesis of cyclopropane isosteres of the antiepilepsy drug vigabatrin and evaluation of their inhibition of GABA aminotransferase. Journal of enzyme inhibition and medicinal chemistry 20040801
Escherichia coli L-serine deaminase requires a [4Fe-4S] cluster in catalysis. The Journal of biological chemistry 20040730
[Hydrogen sulfide as a biologically active mediator in the cardiovascular system]. Postepy higieny i medycyny doswiadczalnej (Online) 20040719
3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells. The Journal of biological chemistry 20040716
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator. Journal of molecular biology 20040716
Cloning, expression, and characterization of 5-aminolevulinic acid synthase from Rhodopseudomonas palustris KUGB306. FEMS microbiology letters 20040715
A molecularly imprinted polymer-based synthetic transaminase. Journal of the American Chemical Society 20040714
pH dependence of tryptophan synthase catalytic mechanism: I. The first stage, the beta-elimination reaction. The Journal of biological chemistry 20040709
Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain. Neurochemistry international 20040701
Photo-induced processes in vitamin B6 compounds. Chemistry & biodiversity 20040701
Structure and mechanism of O-acetylserine sulfhydrylase. The Journal of biological chemistry 20040625
Polymeric and dendrimeric pyridoxal enzyme mimics. Bioorganic & medicinal chemistry 20040615
The loss of circadian PAR bZip transcription factors results in epilepsy. Genes & development 20040615
The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochemistry international 20040601
Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis. Asian journal of andrology 20040601
Genomic organization, tissue distribution and deletion mutation of human pyridoxine 5'-phosphate oxidase. European journal of biochemistry 20040601
Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV. Proteins 20040515
Identification of the mitochondrial GTP/GDP transporter in Saccharomyces cerevisiae. The Journal of biological chemistry 20040514
Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. The Journal of biological chemistry 20040514
N,N'-ethylenebis(pyridoxylideneiminato) and N,N'-ethylenebis(pyridoxylaminato): synthesis, characterization, potentiometric, spectroscopic, and DFT studies of their vanadium(IV) and vanadium(V) complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 20040503
Conformational changes in the reaction of pyridoxal kinase. The Journal of biological chemistry 20040423
Assay method for antitumor L-methionine gamma-lyase: comprehensive kinetic analysis of the complex reaction with L-methionine. Analytical biochemistry 20040415
Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformations. Protein science : a publication of the Protein Society 20040401
4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents. Bulletin du cancer 20040401
Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. The Journal of biological chemistry 20040326
Folic acid and vitamin B12 are more effective than vitamin B6 in lowering fasting plasma homocysteine concentration in patients with coronary artery disease. European journal of clinical nutrition 20040301
Pyridoxal-aminoguanidine adduct is more effective than aminoguanidine in preventing neuropathy and cataract in diabetic rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040301
Vigabatrin inhibits pyridoxine-5'-phosphate oxidase, not pyridoxal kinase in the hippocampus of seizure prone gerbils. Neurochemistry international 20040201
Vitamin B6 metabolites in idiopathic calcium stone formers: no evidence for a link to hyperoxaluria. Urological research 20040201
Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric complexes. Journal of inorganic biochemistry 20040201
Disruption of the plr1+ gene encoding pyridoxal reductase of Schizosaccharomyces pombe. Journal of biochemistry 20040201
Inactivation of gamma-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid does not proceed by the expected aromatization mechanism. Bioorganic & medicinal chemistry letters 20040105
Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. The Journal of biological chemistry 20040102
Cloning and expression of 1-aminocyclopropane-1-carboxylate synthase cDNA from rosa (Rosa x hybrida). Plant cell reports 20040101
Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. Stroke 20040101
Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs. Archives of biochemistry and biophysics 20040101
S-methylmethionine is both a substrate and an inactivator of 1-aminocyclopropane-1-carboxylate synthase. Archives of biochemistry and biophysics 20040101
Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Current topics in medicinal chemistry 20040101
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. Journal of applied microbiology 20040101
COMe: the ontology of bioinorganic proteins. BMC structural biology 20040101
Hypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65). Respiratory research 20040101
Cytosolic NADP phosphatases I and II from Arthrobacter sp. strain KM: implication in regulation of NAD+/NADP+ balance. Journal of basic microbiology 20040101
Function and evolution of the serotonin-synthetic bas-1 gene and other aromatic amino acid decarboxylase genes in Caenorhabditis. BMC evolutionary biology 20040101
Evaluation of vitamin B6 status and RDA in young Koreans. Annals of nutrition & metabolism 20040101
Changes of pyridoxal kinase expression and activity in the gerbil hippocampus following transient forebrain ischemia. Neuroscience 20040101
Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutrition journal 20040101
The differential proteome profile of stomach cancer: identification of the biomarker candidates. Oncology research 20040101
Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders. BMC neurology 20040101
The effect of new lipophilic chelators on the activities of cytosolic reductases and P450 cytochromes involved in the metabolism of anthracycline antibiotics: studies in vitro. Physiological research 20040101
Isolation and characterization of ornithine decarboxylase gene from flounder (Paralichthys olivaceus). Marine biotechnology (New York, N.Y.) 20040101
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon. Biochemical and biophysical research communications 20031226
Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution. The Journal of biological chemistry 20031212
O2 release from Hb vesicles evaluated using an artificial, narrow O2-permeable tube: comparison with RBCs and acellular Hbs. American journal of physiology. Heart and circulatory physiology 20031201
Antioxidant activity of a Schiff base of pyridoxal and aminoguanidine. Free radical biology & medicine 20031201
Pyridoxal 5'-phosphate as a novel weapon against autoimmunity and transplant rejection. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201
In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation. Cancer research 20031201
Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8. Journal of biochemistry 20031201
Role of nucleotide P2 receptors in calcium signaling and prolactin release in pituitary lactotrophs. The Journal of biological chemistry 20031121
Automatic annotation of protein function based on family identification. Proteins 20031115
Crystal structure of serine dehydratase from rat liver. Biochemistry 20031111
The critical structural role of a highly conserved histidine residue in group II amino acid decarboxylases. FEBS letters 20031106
Interaction between pyridoxal kinase and pyridoxal-5-phosphate-dependent enzymes. Journal of biochemistry 20031101
Stereochemistry of the reactions of glutamate-1-semialdehyde aminomutase with 4,5-diaminovalerate. The Journal of biological chemistry 20031017
Reaction intermediate structures of 1-aminocyclopropane-1-carboxylate deaminase: insight into PLP-dependent cyclopropane ring-opening reaction. The Journal of biological chemistry 20031017
Unusual structural, functional, and stability properties of serine hydroxymethyltransferase from Mycobacterium tuberculosis. The Journal of biological chemistry 20031017
A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-derived zinc-chelating trioxa-adamantane-triol. Bioorganic & medicinal chemistry 20031015
Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers 20031001
Complex multivitamin supplementation improves homocysteine and resistance to LDL-C oxidation. Journal of the American College of Nutrition 20031001
Avoiding the road less traveled: how the topology of enzyme-substrate complexes can dictate product selection. Accounts of chemical research 20031001
Conversion of the aminocrotonate intermediate limits the rate of gamma-elimination reaction catalyzed by L-cystathionine gamma-lyase of the yeast Saccharomyces cerevisiae. Journal of biochemistry 20031001
Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris. Biochemistry 20030930
Lysine 238 is an essential residue for alpha,beta-elimination catalyzed by Treponema denticola cystalysin. The Journal of biological chemistry 20030926
A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1. FEBS letters 20030911
Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin. The Journal of pharmacology and experimental therapeutics 20030901
Modeling and molecular dynamics of glutamine transaminase K/cysteine conjugate beta-lyase. Journal of molecular graphics & modelling 20030901
[Vitamin B6 add-on therapy in treatment of schizophrenic patients with psychotic symptoms and movement disorders]. Harefuah 20030901
Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation. Journal of the American Chemical Society 20030827
Role of proline residues in the folding of serine hydroxymethyltransferase. The Journal of biological chemistry 20030815
Design and synthesis of novel pyridoxine 5'-phosphonates as potential antiischemic agents. Journal of medicinal chemistry 20030814
Kinetic differences between the isoforms of glutamate decarboxylase: implications for the regulation of GABA synthesis. Journal of neurochemistry 20030801
Circular permutation of 5-aminolevulinate synthase: effect on folding, conformational stability, and structure. The Journal of biological chemistry 20030725
Optimisation and validation of a sensitive high-performance liquid chromatography assay for routine measurement of pyridoxal 5-phosphate in human plasma and red cells using pre-column semicarbazide derivatisation. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725
Reversed-phase liquid chromatography on an amide stationary phase for the determination of the B group vitamins in baby foods. Journal of chromatography. A 20030725
Inhibitory effect of pyridoxal 5'-phosphate on endothelial cell proliferation, replicative DNA polymerase and DNA topoisomerase. International journal of molecular medicine 20030701
Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase. Protein science : a publication of the Protein Society 20030701
X-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibility. The Journal of biological chemistry 20030613
Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. Biochimica et biophysica acta 20030610
Purification, characterization, and molecular cloning of a novel amine:pyruvate transaminase from Vibrio fluvialis JS17. Applied microbiology and biotechnology 20030601
Cloning and expression of human placental L-Dopa decarboxylase. Neurochemical research 20030601
Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification. Stroke 20030601
Expression of a Brassic napus glutamate 1-semialdehyde aminotransferase in Escherichia coli and characterization of the recombinant protein. Protein expression and purification 20030601
Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets. Biochimie 20030601
Tpn1p, the plasma membrane vitamin B6 transporter of Saccharomyces cerevisiae. The Journal of biological chemistry 20030523
A side reaction of alanine racemase: transamination of cycloserine. Biochemistry 20030520
Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells. Blood 20030515
The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme. Journal of the American Chemical Society 20030514
Tracking interactions that stabilize the dimer structure of starch phosphorylase from Corynebacterium callunae. Roles of Arg234 and Arg242 revealed by sequence analysis and site-directed mutagenesis. European journal of biochemistry 20030501
Inhibition of diphenolase activity of tyrosinase by vitamin b(6) compounds. Journal of agricultural and food chemistry 20030423
Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications. The Biochemical journal 20030415
Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding. Biochimica et biophysica acta 20030411
Alpha,beta-elimination reaction of O-acetylserine sulfhydrylase. Is the pyridine ring required? Biochimica et biophysica acta 20030411
Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase. Biochimica et biophysica acta 20030411
Pyridoxine 5'-phosphate synthase: de novo synthesis of vitamin B6 and beyond. Biochimica et biophysica acta 20030411
Antitumor effect of vitamin B6 and its mechanisms. Biochimica et biophysica acta 20030411
The molecular pathway for the allosteric regulation of tryptophan synthase. Biochimica et biophysica acta 20030411
Structural insights into mutations of cystathionine beta-synthase. Biochimica et biophysica acta 20030411
Phosphate group binding 'cup' of PLP-dependent and non-PLP-dependent enzymes: leitmotif and variations. Biochimica et biophysica acta 20030411
The D-glucosaminate dehydratase alpha-subunit from Pseudomonas fluorescens exhibits thioredoxin reductase activity. Biochimica et biophysica acta 20030411
Release of pyridoxal 5'-phosphate upon unfolding of mitochondrial aspartate aminotransferase. Biochimica et biophysica acta 20030411
Characterization of histidinol phosphate aminotransferase from Escherichia coli. Biochimica et biophysica acta 20030411
5-Aminolevulinic acid synthase: mechanism, mutations and medicine. Biochimica et biophysica acta 20030411
Stability and oligomerization of recombinant GadX, a transcriptional activator of the Escherichia coli glutamate decarboxylase system. Biochimica et biophysica acta 20030411
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme. Biochemistry 20030408
Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors? British journal of cancer 20030407
The status of plasma homocysteine and related B-vitamins in healthy young vegetarians and nonvegetarians. European journal of nutrition 20030401
Ornithine decarboxylase promotes catalysis by binding the carboxylate in a buried pocket containing phenylalanine 397. Biochemistry 20030318
Pyridoxal isonicotinoyl hydrazone inhibits iron-induced ascorbate oxidation and ascorbyl radical formation. Biochimica et biophysica acta 20030317
Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis. The Journal of biological chemistry 20030314
Abnormal vitamin B(6) status is associated with severity of symptoms in patients with rheumatoid arthritis. The American journal of medicine 20030301
Improving lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent by in situ racemization. Biotechnology letters 20030301
Reaction of 1-amino-2-methylenecyclopropane-1-carboxylate with 1-aminocyclopropane-1-carboxylate deaminase: analysis and mechanistic implications. Biochemistry 20030225
Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis. The Biochemical journal 20030201
Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells. Biochemical pharmacology 20030201
Cutaneous metabolism of vitamin B-6. The Journal of investigative dermatology 20030201
The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: a randomized, controlled study. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030201
Purification and characterization of aspartate racemase from the bivalve mollusk Scapharca broughtonii. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201
[Effects of nutritional intervention on brain functions and its related biochemical indexes in mice exposed to high +Gy]. Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20030201
Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate. FEBS letters 20030130
Hydrolysis of pyridoxal isonicotinoyl hydrazone and its analogs. Biochimica et biophysica acta 20030120
Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties. Biochemical pharmacology 20030115
Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation. Biochemical pharmacology 20030115
Structure of a yeast hypothetical protein selected by a structural genomics approach. Acta crystallographica. Section D, Biological crystallography 20030101
Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study. Clinical chemistry 20030101
Cytotoxicity test and cytogenetic analysis of effects of aminoguanidine in vitro. Methods and findings in experimental and clinical pharmacology 20030101
Homocysteine and risk of coronary artery disease: Folate is the important determinant of plasma homocysteine concentration. Nutrition (Burbank, Los Angeles County, Calif.) 20030101
The effect of selected membrane active substances on erythrocyte deformability. Bratislavske lekarske listy 20030101
Thermophile-specific proteins: the gene product of aq_1292 from Aquifex aeolicus is an NTPase. BMC biochemistry 20030101
The effect of vitamin B6 on cognition. The Cochrane database of systematic reviews 20030101
A DNA element recognised by the molybdenum-responsive transcription factor ModE is conserved in Proteobacteria, green sulphur bacteria and Archaea. BMC microbiology 20030101
Preserved function of the Oddi sphincter after endoscopic papillary balloon dilation. Hepato-gastroenterology 20030101
Tryptophan metabolism via transamination. In vitro aminotransferase assay using dinitrophenylhydrazine method. Advances in experimental medicine and biology 20030101
Amino acid racemases: functions and mechanisms. Journal of bioscience and bioengineering 20030101
The PLP-dependent biotin synthase from Escherichia coli: mechanistic studies. FEBS letters 20021218
Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes. Biochemical pharmacology 20021215
Deletion mutagenesis of human cystathionine beta-synthase. Impact on activity, oligomeric status, and S-adenosylmethionine regulation. The Journal of biological chemistry 20021213
Changes in pyridoxal kinase immunoreactivity in the gerbil hippocampus following spontaneous seizure. Brain research 20021213
On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. Journal of molecular biology 20021206
Stereoselectivity in reactions of amino acids catalyzed by pyridoxal derivatives carrying rigidly-attached chirally-mounted basic groups--transamination, racemization, decarboxylation, retro-aldol reaction, and aldol condensation. Bioorganic & medicinal chemistry 20021201
Gene cloning, purification, and characterization of 2,3-diaminopropionate ammonia-lyase from Escherichia coli. Bioscience, biotechnology, and biochemistry 20021201
Purification and characterization of the reconstitutively active adenine nucleotide carrier from mitochondria of Jerusalem artichoke (Helianthus tuberosus L.) tubers. Journal of bioenergetics and biomembranes 20021201
Mechanism of 5-aminolevulinate synthase and the role of the protein environment in controlling the cofactor chemistry. Cellular and molecular biology (Noisy-le-Grand, France) 20021201
A structure-based design approach for the identification of novel inhibitors: application to an alanine racemase. Journal of computer-aided molecular design 20021201
Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily. The Journal of biological chemistry 20021129
Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism. The Journal of biological chemistry 20021122
Capillary electrophoresis assay of alanine:glyoxylate aminotransferase activity in rat liver. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021115
Degradation pathway of the phosphonate ciliatine: crystal structure of 2-aminoethylphosphonate transaminase. Biochemistry 20021105
Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter. Neurochemistry international 20021101
Proteinuria as a predictor of total plasma homocysteine levels in type 2 diabetic nephropathy. Diabetes care 20021101
Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression. American journal of kidney diseases : the official journal of the National Kidney Foundation 20021101
Characterization of a NifS-like chloroplast protein from Arabidopsis. Implications for its role in sulfur and selenium metabolism. Plant physiology 20021101
Purification, properties, and partial amino acid sequences of alanine racemase from the muscle of the black tiger prawn Penaeus monodon. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20021101
Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms. Journal of the American Society of Nephrology : JASN 20021001
Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6. Yeast (Chichester, England) 20021001
Characterization of recombinant YakC of Schizosaccharomyces pombe showing YakC defines a new family of aldo-keto reductases. Journal of biochemistry 20021001
Transition metal complexes with thiosemicarbazide-based ligands. XLIV. Aqua(3-hydroxy-5-hydroxymethyl-2-methylpyridine-4-carboxaldehyde 3-methylisothiosemicarbazone-kappa(3)O,N1,N4)nitratocopper(II) nitrate. Acta crystallographica. Section C, Crystal structure communications 20021001
Bacterial cysteine desulfurases: their function and mechanisms. Applied microbiology and biotechnology 20021001
Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli. European journal of biochemistry 20021001
Vitamin B-6 content of breast milk and neonatal behavioral functioning. Journal of the American Dietetic Association 20021001
Design of pyridoxal 5'-phosphate dependent catalytic antibodies. Biochemistry. Biokhimiia 20021001
Pyridoxal 5'-phosphate as a catalytic and conformational cofactor of muscle glycogen phosphorylase B. Biochemistry. Biokhimiia 20021001
Structural insight into gene duplication, gene fusion and domain swapping in the evolution of PLP-independent amino acid racemases. FEBS letters 20020925
Ornithine decarboxylase encoded by chlorella virus PBCV-1. Virology 20020915
Beta-replacement reaction of serine-O-carbonate derivatives with thiols catalyzed by a pyridoxal model having an ionophore side-chain. Chemical communications (Cambridge, England) 20020907
The AtNFS2 gene from Arabidopsis thaliana encodes a NifS-like plastidial cysteine desulphurase. The Biochemical journal 20020901
Homogeneous, nonradioactive, enzymatic assay for plasma pyridoxal 5-phosphate. Clinical chemistry 20020901
Crystallization and preliminary crystallographic studies of pyridoxal kinase from sheep brain. Acta crystallographica. Section D, Biological crystallography 20020901
Effects of folic acid and vitamin B12 supplements on folate and homocysteine metabolism in pigs during early pregnancy. The British journal of nutrition 20020901
Cloning and characterization of Arabidopsis thaliana pyridoxal kinase. Planta 20020901
Differential scanning calorimetry and scanning thermal microscopy analysis of pharmaceutical materials. International journal of pharmaceutics 20020828
Sp1 and Sp3 transcription factors mediate malondialdehyde-induced collagen alpha 1(I) gene expression in cultured hepatic stellate cells. The Journal of biological chemistry 20020823
Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. Biochemical pharmacology 20020815
Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human. Chemico-biological interactions 20020815
Proton transfers in the beta-reaction catalyzed by tryptophan synthase. Biochemistry 20020806
Isolation, characterization, and functional expression of kynurenine aminotransferase cDNA from the yellow fever mosquito, Aedes aegypti(1). Insect biochemistry and molecular biology 20020801
The role of oxidative stress in the toxicity of pyridoxal isonicotinoyl hydrazone (PIH) analogues. Biochemical Society transactions 20020801
Entamoeba histolytica: purification and characterization of ornithine decarboxylase. Experimental parasitology 20020801
Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes. Biochemistry 20020723
Biotin synthase is a pyridoxal phosphate-dependent cysteine desulfurase. Biochemistry 20020723
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin. Biochemistry 20020723
Identification of a novel pyridoxal 5'-phosphate binding site in adenosylcobalamin-dependent lysine 5,6-aminomutase from Porphyromonas gingivalis. Biochemistry 20020709
Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase. Biochemical and biophysical research communications 20020705
Evidence of poor vitamin status in coeliac patients on a gluten-free diet for 10 years. Alimentary pharmacology & therapeutics 20020701
Aminoguanidine pyridoxal adduct is superior to aminoguanidine for preventing diabetic nephropathy in mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020701
Affinity labeling of the guanine nucleotide binding site of transducin by pyridoxal 5'-phosphate. Journal of protein chemistry 20020701
Methanococcus jannaschii uses a pyruvoyl-dependent arginine decarboxylase in polyamine biosynthesis. The Journal of biological chemistry 20020628
Purification, characterization, and crystallization of alliinase from garlic. Archives of biochemistry and biophysics 20020615
Chronological changes in pyridoxine-5'-phosphate oxidase immunoreactivity in the seizure-sensitive gerbil hippocampus. Journal of neuroscience research 20020615
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes. The Journal of biological chemistry 20020614
Vitamin B6 protects primate retinal neurons from ischemic injury. Brain research 20020614
Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell culture. Apoptosis : an international journal on programmed cell death 20020601
Determination of vitamin B6 vitamers and pyridoxic acid in plasma: development and evaluation of a high-performance liquid chromatographic assay. Analytical biochemistry 20020601
Beta-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines. The Journal of pharmacology and experimental therapeutics 20020601
SOS4, a pyridoxal kinase gene, is required for root hair development in Arabidopsis. Plant physiology 20020601
Inhibition of bacterial pyridoxal-depending enzymes by (aminooxy)-acetic acid improves selective 15N isotope labeling of bacterially expressed protein. BioTechniques 20020601
Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization. Journal of molecular biology 20020531
Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. The Journal of biological chemistry 20020524
Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine. Journal of biochemistry 20020501
Vitamin B6 intakes and status of mechanically ventilated critically ill patients in Taiwan. European journal of clinical nutrition 20020501
Reactive intermediate formation from the 2-(Fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived cysteine S-conjugate S-[2-(Fluoromethoxy)-1,1,3,3,3-pentafluoropropyl]-L-cysteine in pyridoxal model systems. Chemical research in toxicology 20020501
Purification, molecular cloning, and characterization of pyridoxine 4-oxidase from Microbacterium luteolum. Bioscience, biotechnology, and biochemistry 20020501
An enzymatic fluorometric assay for pyridoxal with high specificity and sensitivity. Bioscience, biotechnology, and biochemistry 20020501
Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica. Biochemistry 20020416
Structure and function of threonine synthase from yeast. The Journal of biological chemistry 20020405
Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier. Journal of biochemistry 20020401
Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence. Biochimica et biophysica acta 20020401
Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor. Biochimica et biophysica acta 20020401
Purification and biochemical characterization of some of the properties of recombinant human kynureninase. European journal of biochemistry 20020401
Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A 'knock-out' allosteric enzyme. The Journal of biological chemistry 20020322
Mutations in the yeast LCB1 and LCB2 genes, including those corresponding to the hereditary sensory neuropathy type I mutations, dominantly inactivate serine palmitoyltransferase. The Journal of biological chemistry 20020322
The Arabidopsis salt overly sensitive 4 mutants uncover a critical role for vitamin B6 in plant salt tolerance. The Plant cell 20020301
Purification and characterization of pyridoxal 4-dehydrogenase from Aureobacterium luteolum. Bioscience, biotechnology, and biochemistry 20020301
Cysteine synthase of an extremely thermophilic bacterium, Thermus thermophilus HB8. Bioscience, biotechnology, and biochemistry 20020301
Modified antimicrobial disc susceptibility testing for nutritionally-variant streptococci. The Southeast Asian journal of tropical medicine and public health 20020301
Design of a conformationally restricted analogue of the antiepilepsy drug Vigabatrin that directs its mechanism of inactivation of gamma-aminobutyric acid aminotransferase. Journal of the American Chemical Society 20020227
Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxidoprogesterone. Biochimica et biophysica acta 20020213
Cold-induced enzyme inactivation: how does cooling lead to pyridoxal phosphate-aldimine bond cleavage in tryptophanase? Biochimica et biophysica acta 20020211
Circular permutation of 5-aminolevulinate synthase as a tool to evaluate folding, structure and function. Cellular and molecular biology (Noisy-le-Grand, France) 20020201
Vitamin B6 status of breast-fed infants in relation to pyridoxine HCl supplementation of mothers. Journal of nutritional science and vitaminology 20020201
Chemical modification of specific active site amino acid residues of Enterobacter aerogenes glycerol dehydrogenase. Journal of enzyme inhibition and medicinal chemistry 20020201
Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase. Journal of molecular biology 20020118
Inhibition of camel lens zeta-crystallin by aspirin and aspirin-like analgesics. The international journal of biochemistry & cell biology 20020101
Plasma total homocysteine levels among patients undergoing nocturnal versus standard hemodialysis. Journal of the American Society of Nephrology : JASN 20020101
Vitamin B6 metabolism and homocysteine in end-stage renal disease and chronic renal insufficiency. American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101
Significance of two distinct types of tryptophan synthase beta chain in Bacteria, Archaea and higher plants. Genome biology 20020101
Production of diamino propionic acid ammonia lyase by a new strain of Salmonella typhimurium PU011. BMC microbiology 20020101
Homocysteine, vitamin B(6), and lipid in cardiovascular disease. Nutrition (Burbank, Los Angeles County, Calif.) 20020101
Rapid determination of thiamine, riboflavin, pyridoxine, and niacinamide in infant formulas by liquid chromatography. Journal of AOAC International 20020101
Vitamin B6 status of children with sickle cell disease. Journal of pediatric hematology/oncology 20020101
Cardiac troponin T following repeated administration of pyridoxal isonicotinoyl hydrazone in rabbits. Physiological research 20020101
Alterations of non-enzymatic biochemistry in uremia, diabetes, and atherosclerosis ('carbonyl stress'). Bulletin et memoires de l'Academie royale de medecine de Belgique 20020101
Pyridoxal isonicotinoyl hydrazone and its analogues. Advances in experimental medicine and biology 20020101
Therapeutic potential of iron chelators in cancer therapy. Advances in experimental medicine and biology 20020101
yaaD and yaaE are involved in vitamin B6 biosynthesis in Bacillus subtilis. Journal of bioscience and bioengineering 20020101
Pyridoxal 5'-phosphate inhibits DNA binding of HNF1. Biochimica et biophysica acta 20011219
Pyridoxal isonicotinoyl hydrazone (PIH) prevents copper-mediated in vitro free radical formation. Molecular and cellular biochemistry 20011201
Influence of convulsants on rat brain activities of alanine aminotransferase and aspartate aminotransferase. Neurochemical research 20011201
Modulation of gene expression by vitamin B6. Nutrition research reviews 20011201
Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-ornithine aminomutase from Clostridium sticklandii. The Journal of biological chemistry 20011130
DnaA protein Lys-415 is close to the ATP-binding site: ATP-pyridoxal affinity labeling. Biochemical and biophysical research communications 20011116
Microassay of phosphate provides a general method for measuring the activity of phosphatases using physiological, nonchromogenic substrates such as lysophosphatidic acid. Analytical biochemistry 20011115
Distribution of B6 vitamers in Escherichia coli as determined by enzymatic assay. Analytical biochemistry 20011115
Long-range interactions in the dimer interface of ornithine decarboxylase are important for enzyme function. Biochemistry 20011106
Pyridoxal 5'-phosphate and pyridoxal inhibit angiogenesis in serum-free rat aortic ring assay. International journal of molecular medicine 20011101
Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate. Atherosclerosis 20011101
Glycogen and glycogen phosphorylase associated with sarcoplasmic reticulum: effects of fatiguing activity. Journal of applied physiology (Bethesda, Md. : 1985) 20011001
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk. Carcinogenesis 20011001
Contribution of enzymic alpha, gamma-elimination reaction in detoxification pathway of selenomethionine in mouse liver. Toxicology and applied pharmacology 20011001
Seizures induced by intracerebral administration of pyridoxal-5'-phosphate: effect of GABAergic drugs and glutamate receptor antagonists. Neuropharmacology 20011001
The iron chelator pyridoxal isonicotinoyl hydrazone inhibits mitochondrial lipid peroxidation induced by Fe(II)-citrate. European journal of pharmacology 20010928
Plants synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme. The Journal of biological chemistry 20010921
Biocatalysis of isomerization of 1,2-benzisoxazole by bovine serum albumin in an organic solvent. Biotechnology and bioengineering 20010920
Enzyme catalysis of 1,2-amino shifts: the cooperative action of B6, B12, and aminomutases. Journal of the American Chemical Society 20010912
Cloning and overexpression of the oah1 gene encoding O-acetyl-L-homoserine sulfhydrylase of Thermus thermophilus HB8 and characterization of the gene product. Biochimica et biophysica acta 20010910
Vitamin B6 intakes and status assessment of elderly men and women in Taiwan. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010901
P2X3 knock-out mice reveal a major sensory role for urothelially released ATP. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression. Blood 20010801
Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein. The EMBO journal 20010801
The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: functional characterization. Microbiology (Reading, England) 20010801
Experimental model of pyridoxine (B6) deficiency-induced neuropathy. Annals of plastic surgery 20010801
Production of pyridoxal phosphate by a mutant strain of Schizosaccharomyces pombe. Bioscience, biotechnology, and biochemistry 20010801
PLP and PMP radicals: a new paradigm in coenzyme B6 chemistry. Bioorganic chemistry 20010801
X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. Journal of molecular biology 20010720
Influence of pyridoxal 5'-phosphate alone and in combination with vigabatrin on brain GABA measured by 1H-NMR-spectroscopy. Brain research bulletin 20010701
Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels. Circulation 20010612
Circular permutation of 5-aminolevulinate synthase. Mapping the polypeptide chain to its function. The Journal of biological chemistry 20010601
Sensitivity to meat protein intake and hyperoxaluria in idiopathic calcium stone formers. Kidney international 20010601
Genomic structure, developmental distribution and functional properties of the chicken P2X(5) receptor. Journal of neurochemistry 20010601
Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis. European journal of biochemistry 20010601
The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity. Plant physiology 20010601
Vitamin B1 and B6 retention in milk after continuous-flow microwave and conventional heating at high temperatures. Journal of food protection 20010601
Effect of feeding on circulating micronutrient concentrations in the Burmese python (Python molurus). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010601
Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues. Journal of nutritional science and vitaminology 20010601
Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron. Biochimica et biophysica acta 20010531
A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction. The Journal of biological chemistry 20010525
Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour. Arteriosclerosis, thrombosis, and vascular biology 20010501
Chronic renal transplantation: a model for the hyperhomocysteinemia of renal insufficiency. Atherosclerosis 20010501
Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum. Archives of biochemistry and biophysics 20010415
Molecular heterogeneity of O-acetylserine sulfhydrylase by two-photon excited fluorescence fluctuation spectroscopy. Biophysical journal 20010401
Effect of energy restriction and exercise on vitamin B-6 status of women during lactation. Medicine and science in sports and exercise 20010401
[Effect of various substrate nutrient on the spore germination and infective germ tube inducing of Pandora delphacis]. Wei sheng wu xue bao = Acta microbiologica Sinica 20010401
Specific labeling of the bovine heart mitochondrial phosphate carrier with fluorescein 5-isothiocyanate: roles of Lys185 and putative adenine nucleotide recognition site in phosphate transport. The Journal of biological chemistry 20010330
A model for enzyme-substrate interaction in alanine racemase. Journal of the American Chemical Society 20010328
Complexities of measuring antagonist potency at P2X(7) receptor orthologs. The Journal of pharmacology and experimental therapeutics 20010301
Effect of phosphate on stability of pyridoxal in the presence of lysine. Journal of agricultural and food chemistry 20010301
Clinical adaptation of a high-performance liquid chromatographic method for the assay of pyridoxal 5'-phosphate in human plasma. Journal of chromatography. B, Biomedical sciences and applications 20010225
Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum. Biochemical and biophysical research communications 20010223
Electrophysiologic endpoint measures in a multicenter ALS drug trial. Journal of the neurological sciences 20010215
Rapid kinetic and isotopic studies on dialkylglycine decarboxylase. Biochemistry 20010206
Computational studies on nonenzymatic and enzymatic pyridoxal phosphate catalyzed decarboxylations of 2-aminoisobutyrate. Biochemistry 20010206
Purification and characterization of tyrosine decarboxylase of Lactobacillus brevis IOEB 9809 isolated from wine. FEMS microbiology letters 20010205
Vitamin B6 (pyridoxine and pyridoxal 5'-phosphate) - monograph. Alternative medicine review : a journal of clinical therapeutic 20010201
Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. Journal of medicinal chemistry 20010201
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase. Biochemistry 20010116
Identification of lysine 346 as a functionally important residue for pyridoxal 5'-phosphate binding and catalysis in lysine 2, 3-aminomutase from Bacillus subtilis. Biochemistry 20010116
Functional properties of the active core of human cystathionine beta-synthase crystals. The Journal of biological chemistry 20010105
Biosynthesis of vitamin B6 and structurally related derivatives. Vitamins and hormones 20010101
Biosynthesis of biotin and lipoic acid. Vitamins and hormones 20010101
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. European journal of biochemistry 20010101
Purification and some properties of alanine racemase from a bivalve mollusc Corbicula japonica. The Journal of experimental zoology 20010101
Abnormal vitamin B6 metabolism in alkaline phosphatase knock-out mice causes multiple abnormalities, but not the impaired bone mineralization. The Journal of pathology 20010101
Pyridoxal 5'-phosphate-dependent alpha,beta-elimination reactions: mechanism of O-acetylserine sulfhydrylase. Accounts of chemical research 20010101
Determination of vitamin B(6) in cooked sausages. Journal of agricultural and food chemistry 20010101
Longitudinal vitamin and homocysteine levels in normal pregnancy. The British journal of nutrition 20010101
Enzymes by design: chemogenetic assembly of transamination active sites containing lysine residues for covalent catalysis. Bioconjugate chemistry 20010101
Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. Acta biochimica Polonica 20010101
Neuroprotective effects of pyridoxal phosphate and pyridoxal against ischemia in monkeys. Nutritional neuroscience 20010101
Stereospecificity for the hydrogen transfer of pyridoxal enzyme reactions. Chemical record (New York, N.Y.) 20010101
[Depression of serum pyridoxal levels in theophylline-related seizures]. No to hattatsu = Brain and development 20000701
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. Nature genetics 19950901
Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate. Antimicrobial agents and chemotherapy 19941001
Isoniazid inhibition of mycolic acid synthesis by cell extracts of sensitive and resistant strains of Mycobacterium aurum. Antimicrobial agents and chemotherapy 19910601
Enzymes of vitamin B6 degradation. Purification and properties of 5-pyridoxic-acid oxygenase from Arthrobacter sp. The Journal of biological chemistry 19861115
Covalently modified peptides isolated from aspartate aminotransferase after reaction with pyridoxal 5'-sulfate. Biochemistry 19821012
Seizure susceptibility in the developing mouse and its relationship to glutamate decarboxylase and pyridoxal phosphate in brain. Journal of neurobiology 19750301
The bacterial oxidation of vitamin B6. V. The enzymatic formation of pyridoxal and isopyridoxal from pyridoxine. The Journal of biological chemistry 19690525

© 2019 Angene International Limited. All rights Reserved.