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65-46-3

65-46-3 | 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone

CAS No: 65-46-3 Catalog No: AG0034OB MDL No:MFCD00006545

Product Description

Catalog Number:
AG0034OB
Chemical Name:
4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone
CAS Number:
65-46-3
Molecular Formula:
C9H13N3O5
Molecular Weight:
243.2166
MDL Number:
MFCD00006545
IUPAC Name:
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChI:
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
InChI Key:
UHDGCWIWMRVCDJ-XVFCMESISA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(nc1=O)N
EC Number:
200-610-9
UNII:
5CSZ8459RP

Properties

Complexity:
383  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
243.086g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
243.219g/mol
Monoisotopic Mass:
243.086g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
129A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.1  

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Unprecedented C-selective interstrand cross-linking through in situ oxidation of furan-modified oligodeoxynucleotides. Journal of the American Chemical Society 20110202
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The role of FKBP5 in cancer aetiology and chemoresistance. British journal of cancer 20110104
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Complete genome sequence of a serotype 11A, ST62 Streptococcus pneumoniae invasive isolate. BMC microbiology 20110101
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A high-throughput assay for DNA deaminases. Methods in molecular biology (Clifton, N.J.) 20110101
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Newly engineered magnetic erythrocytes for sustained and targeted delivery of anti-cancer therapeutic compounds. PloS one 20110101
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Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells. Genome biology 20110101
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MetaPath: identifying differentially abundant metabolic pathways in metagenomic datasets. BMC proceedings 20110101
Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference. International journal of Alzheimer's disease 20110101
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Complete genome sequence of Mycoplasma suis and insights into its biology and adaption to an erythrocyte niche. PloS one 20110101
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The first sequenced carnivore genome shows complex host-endogenous retrovirus relationships. PloS one 20110101
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Genomic characterization of Haemophilus parasuis SH0165, a highly virulent strain of serovar 5 prevalent in China. PloS one 20110101
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StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase. BMC bioinformatics 20110101
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Increasing the analytical sensitivity by oligonucleotides modified with para- and ortho-twisted intercalating nucleic acids--TINA. PloS one 20110101
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Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies. PloS one 20110101
Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U. PloS one 20110101
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Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface. Nanoscale research letters 20110101
A new drug design targeting the adenosinergic system for Huntington's disease. PloS one 20110101
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Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. PloS one 20110101
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Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC. Frontiers in microbiology 20110101
Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans. PloS one 20110101
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A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression. Molecular cancer 20110101
Strong association of 677 C>T substitution in the MTHFR gene with male infertility--a study on an indian population and a meta-analysis. PloS one 20110101
Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression. Frontiers in psychiatry 20110101
New hepatitis C therapies in clinical development. European journal of medical research 20110101
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Inhibition of DNA methylation in somatic cells. Methods in molecular biology (Clifton, N.J.) 20110101
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Calculation of direct antiretroviral treatment costs and potential cost savings by using generics in the German HIV ClinSurv cohort. PloS one 20110101
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Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence. Veterinary research 20110101
Towards in vivo imaging of cancer sialylation. International journal of molecular imaging 20110101
High resolution analysis of the chromatin landscape of the IgE switch region in human B cells. PloS one 20110101
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Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys. Retrovirology 20110101
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Naturally occurring genotype 2b/1a hepatitis C virus in the United States. Virology journal 20110101
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Some aspects of purinergic signaling in the ventricular system of porcine brain. Acta veterinaria Scandinavica 20110101
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A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia. BMC medical genetics 20110101
Homologous expression of a subcomplex of Pyrococcus furiosus hydrogenase that interacts with pyruvate ferredoxin oxidoreductase. PloS one 20110101
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An autoimmune disease prevented by anti-retroviral drugs. Retrovirology 20110101
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Novel strategy with gemcitabine for advanced pancreatic cancer. ISRN oncology 20110101
Pharmacotherapeutic implications of the association between genomic instability at chromosome 15q13.3 and autism spectrum disorders. Clinical neuropharmacology 20110101
An efficient vector system to modify cells genetically. PloS one 20110101
A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy. PloS one 20110101
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Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis. BMC structural biology 20110101
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Biased use of the IGHV4 family and evidence for antigen selection in Chlamydophila psittaci-negative ocular adnexal extranodal marginal zone lymphomas. PloS one 20110101
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A concise review on epigenetic regulation: insight into molecular mechanisms. International journal of molecular sciences 20110101
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Replication of alphaviruses: a review on the entry process of alphaviruses into cells. Advances in virology 20110101
Murine leukemia viruses: objects and organisms. Advances in virology 20110101
XMRV Discovery and Prostate Cancer-Related Research. Advances in virology 20110101
Intraperitoneal gemcitabine chemotherapy treatment for patients with resected pancreatic cancer: rationale and report of early data. International journal of surgical oncology 20110101
Genome-wide essential gene identification in Streptococcus sanguinis. Scientific reports 20110101
One-pot bio-synthesis: N-acetyl-D-neuraminic acid production by a powerful engineered whole-cell catalyst. Scientific reports 20110101
Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines. Clinical epigenetics 20110101
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Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification. The Journal of biological chemistry 20101224
APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions. Cell host & microbe 20101216
Translocator protein (TSPO) ligand-Ara-C (cytarabine) conjugates as a strategy to deliver antineoplastic drugs and to enhance drug clinical potential. Molecular pharmaceutics 20101206
A new site-directed transgenic rheumatoid factor mouse model demonstrates extrafollicular class switch and plasmablast formation. Autoimmunity 20101201
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer. Gastroenterology 20101201
Lymphoid neogenesis in the giant papillae of patients with chronic allergic conjunctivitis. The Journal of allergy and clinical immunology 20101201
Recapture of hepatic apolipoprotein B mRNA editing may be a promising strategy to relieve nephrotic dyslipidemia. Medical hypotheses 20101201
Arsenic modulates APOBEC3G-mediated restriction to HIV-1 infection in myeloid dendritic cells. Journal of leukocyte biology 20101201
A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia. Clinical chemistry 20101201
Assessment of mitochondria as a compartment for phosphatidylinositol synthesis in Solanum tuberosum. Plant physiology and biochemistry : PPB 20101201
Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon. Analytical chemistry 20101201
Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. The Journal of clinical investigation 20101201
Two special topics on the avian influenza virus and on epigenetics, have drawn much attention. Science China. Life sciences 20101201
Cytotoxicity and antileukaemic activity of new duplexes linking 3-C-ethynylcytidine and 5-fluorodeoxyuridine. Anticancer research 20101201
A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. PLoS genetics 20101201
Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. PLoS pathogens 20101201
Identification of mouse mutant cells exhibiting plastic mutant phenotype II; ionizing radiation-induced mutant phenotype plasticity is not dependent on DNA methylation of the hypoxanthine phosphoribosyl transferase gene in mouse FM3A cells. Bioscience trends 20101201
Cytosine methyltransferases as tumor markers. Current genomics 20101201
Profound differences in virus population genetics correspond to protection from CD4 decline resulting from feline lentivirus coinfection. Viruses 20101201
Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans. Vaccine 20101129
When bacteria become mutagenic and carcinogenic: lessons from H. pylori. Mutation research 20101128
Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation. The Journal of biological chemistry 20101126
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase. Journal of medicinal chemistry 20101125
Chemoselective multicomponent one-pot assembly of purine precursors in water. Journal of the American Chemical Society 20101124
A recombinant α-(2→3)-sialyltransferase with an extremely broad acceptor substrate specificity from Photobacterium sp. JT-ISH-224 can transfer N-acetylneuraminic acid to inositols. Carbohydrate research 20101122
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells. Experimental cell research 20101115
Label-free DNA methylation analysis using opto-fluidic ring resonators. Biosensors & bioelectronics 20101115
Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes. The Journal of biological chemistry 20101112
How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA. Science (New York, N.Y.) 20101112
Isolation and identification of ester impurities in RG7128, an HCV polymerase inhibitor. Journal of pharmaceutical and biomedical analysis 20101102
Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes. Biochimica et biophysica acta 20101101
Production of cytidine 5'-diphosphorylcholine with high utilization of ATP by whole cells of Saccharomyces cerevisiae. Bioresource technology 20101101
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Activation of the type I interferon pathway in primary Sjogren's syndrome. Journal of autoimmunity 20101101
DNA methylation regulates cocaine-induced behavioral sensitization in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20101101
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Analysis of hydrophilic and lipophilic choline compounds in radioresistant and radiosensitive glioblastoma cell lines by HILIC-ESI-MS/MS. Analytical and bioanalytical chemistry 20101101
Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line. The FEBS journal 20101101
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A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells. Journal of immunology (Baltimore, Md. : 1950) 20101101
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Contribution of thymidylate synthase to gemcitabine therapy for advanced pancreatic cancer. Pancreas 20101101
Nanomechanical recognition measurements of individual DNA molecules reveal epigenetic methylation patterns. Nature nanotechnology 20101101
Alkaloidal constituents of Tinospora crispa. Natural product communications 20101101
Targeted serum metabolite profiling of nucleosides in esophageal adenocarcinoma. Rapid communications in mass spectrometry : RCM 20101030
An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer. Science translational medicine 20101020
Method for the rapid detection and molecular characterization of DNA alkylating agents by MALDI-TOF mass spectrometry. Analytical chemistry 20101015
Photoelectron spectroscopic study of the hydrated nucleoside anions: Uridine(-)(H(2)O)(n=0-2), cytidine(-)(H(2)O)(n=0-2), and thymidine(-)(H(2)O)(n=0,1). The Journal of chemical physics 20101014
Archaeal RibL: a new FAD synthetase that is air sensitive. Biochemistry 20101012
Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif. Journal of molecular biology 20101008
PCR-based methods for CDA K27Q and A70T genotyping: genotypes and alleles distribution in a central Italy population. Molecular biology reports 20101001
Biophysical characterization of recombinant proteins: a key to higher structural genomics success. Journal of structural biology 20101001
An investigation of intracellular glycosylation activities in CHO cells: effects of nucleotide sugar precursor feeding. Biotechnology and bioengineering 20101001
Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogs in vitro and in vivo. Drug metabolism and disposition: the biological fate of chemicals 20101001
Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mitochondrial genomes. Current genetics 20101001
Regulation of HIV-1 infection in cells derived from purified CD34+ cells through manipulation of APOBEC3G expression. Current HIV research 20101001
Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure. Journal of virology 20101001
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Development of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues. Cancer gene therapy 20090701
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AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity. Nature structural & molecular biology 20090701
The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity. European journal of immunology 20090701
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Possible contribution of DNase gamma to immunoglobulin V gene diversification. Immunology letters 20090630
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. Journal of molecular biology 20090626
Decreased expression of cholesterol 7alpha-hydroxylase and altered bile acid metabolism in Apobec-1-/- mice lead to increased gallstone susceptibility. The Journal of biological chemistry 20090619
Total syntheses of a conformationally locked North-type methanocarba puromycin analogue and a dinucleotide derivative. Chemistry (Weinheim an der Bergstrasse, Germany) 20090615
Synthesis of terminally modified oligonucleotides and their hybridization dependence on the size of the target RNAs. Organic & biomolecular chemistry 20090607
Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma. British journal of cancer 20090602
Accurate micro- and macro- gas phase basicities of hydroxyl-radical-modified pyrimidines estimated by advanced quantum chemistry methods. Journal of molecular modeling 20090601
Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601
The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia 20090601
Molecular cloning and expression of a novel cholinephosphotransferase involved in glycoglycerophospholipid biosynthesis of Mycoplasma fermentans. Current microbiology 20090601
Analysis of urinary nucleosides as helper tumor markers in hepatocellular carcinoma diagnosis. Rapid communications in mass spectrometry : RCM 20090601
G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection. The Journal of infectious diseases 20090601
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation. Biochemical Society transactions 20090601
Bilateral renal-cell carcinoma associated with an acquired VHL mutation and long-term trichloroethylene exposure. Clinical nephrology 20090601
Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1. PLoS pathogens 20090601
Global HIV-1 molecular epidemiology with special reference to genetic analysis of HIV-1 subtypes circulating in North India: functional and pathogenic implications of genetic variation. Indian journal of experimental biology 20090601
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Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy. The Journal of biological chemistry 20090515
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Ionization energies of aqueous nucleic acids: photoelectron spectroscopy of pyrimidine nucleosides and ab initio calculations. Journal of the American Chemical Society 20090513
Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent. Virology 20090510
Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development. Blood 20090507
Enzymatic synthesis of sialylation substrates powered by a novel polyphosphate kinase (PPK3). Organic & biomolecular chemistry 20090507
Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile. Cancer chemotherapy and pharmacology 20090501
Lasting epigenetic influence of early-life adversity on the BDNF gene. Biological psychiatry 20090501
Identification and functional characterization of a novel cytidine deaminase in a gastropod abalone, Haliotis diversicolor supertexta. Developmental and comparative immunology 20090501
DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin. Mutagenesis 20090501
Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics 20090501
A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers. The Journal of infectious diseases 20090501
Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients. The Journal of infectious diseases 20090501
Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090501
1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo. International journal of oncology 20090501
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nature immunology 20090501
Thymidine kinase and uridine-cytidine kinase from Entamoeba histolytica: cloning, characterization, and search for specific inhibitors. Parasitology 20090501
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A cytidine deaminase edits C to U in transfer RNAs in Archaea. Science (New York, N.Y.) 20090501
Active nuclear import and cytoplasmic retention of activation-induced deaminase. Nature structural & molecular biology 20090501
Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA. Nature structural & molecular biology 20090501
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A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. Journal of medicinal chemistry 20090423
DFT study of the interaction of cytidine and 2'-deoxycytidine with Li+, Na+, and K+: effects of metal cationization on sugar puckering and stability of the N-glycosidic bond. Carbohydrate research 20090421
Methodological approaches in application of synthetic lethality screening towards anticancer therapy. British journal of cancer 20090421
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A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes. Biosensors & bioelectronics 20090415
A robust quantitative solid phase immunoassay for the acute phase protein C-reactive protein (CRP) based on cytidine 5'-diphosphocholine coupled dendrimers. Journal of immunological methods 20090415
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Analysis of urinary nucleosides as potential tumor markers in human colorectal cancer by high performance liquid chromatography/electrospray ionization tandem mass spectrometry. Clinica chimica acta; international journal of clinical chemistry 20090401
Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production. Molecular immunology 20090401
Exogenous adenosine reduces the mitochondrial membrane potential of murine oocytes during the latter half of in vitro maturation and pronuclear formation following chemical activation. The Journal of reproduction and development 20090401
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Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance. PLoS pathogens 20090401
Impaired antibody response causes persistence of prototypic T cell-contained virus. PLoS biology 20090401
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Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis. Biochemistry 20090331
Homozygous CDA*3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients. British journal of cancer 20090324
Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene. Virology 20090315
Ectopic germinal centers are rare in Sjogren's syndrome salivary glands and do not exclude autoreactive B cells. Journal of immunology (Baltimore, Md. : 1950) 20090315
Dissecting APOBEC3G substrate specificity by nucleoside analog interference. The Journal of biological chemistry 20090313
Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Preface. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Immunoglobulin class switch recombination: study through human natural mutants. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Non-homologous end joining in class switch recombination: the beginning of the end. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
APOBEC3G: an intracellular centurion. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Competitive repair pathways in immunoglobulin gene hypermutation. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Post-translational regulation of activation-induced cytidine deaminase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Molecular mechanism for generation of antibody memory. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
APOBEC proteins and intrinsic resistance to HIV-1 infection. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Powerful mutators lurking in the genome. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312
Pancreatic cancer: translating lessons from mouse models. JOP : Journal of the pancreas 20090309
Therapeutic tools in pancreatic cancer. JOP : Journal of the pancreas 20090309
DNA hairpins containing the cytidine analog pyrrolo-dC: structural, thermodynamic, and spectroscopic studies. Biophysical journal 20090304
Phosphorothioation of oligonucleotides strongly influences the inhibition of bacterial (M.HhaI) and human (Dnmt1) DNA methyltransferases. Chembiochem : a European journal of chemical biology 20090302
Development of selective agonists and antagonists of P2Y receptors. Purinergic signalling 20090301
Epigenetic regulation of human buccal mucosa mitochondrial superoxide dismutase gene expression by diet. The British journal of nutrition 20090301
Medium-dependent interactions of quinones with cytosine and cytidine: a laser flash photolysis study with magnetic field effect. Biophysical chemistry 20090301
Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis C virus NS5B polymerase. Bioorganic & medicinal chemistry letters 20090301
Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models. International journal of oncology 20090301
The SET complex acts as a barrier to autointegration of HIV-1. PLoS pathogens 20090301
RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1. PLoS pathogens 20090301
Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cells. PLoS pathogens 20090301
Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes. Immunology 20090301
The expression of activation induced cytidine deaminase in follicular lymphoma is independent of prognosis and stage. Histopathology 20090301
Biomedical discovery acceleration, with applications to craniofacial development. PLoS computational biology 20090301
Citicoline protects against cognitive impairment in a rat model of chronic cerebral hypoperfusion. Journal of clinical neurology (Seoul, Korea) 20090301
[Determination of cytidine and adenosine in cordyceps by monolithiccapillary electrochromatography]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301
Species-specific inhibition of APOBEC3C by the prototype foamy virus protein bet. The Journal of biological chemistry 20090227
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice. Proceedings of the National Academy of Sciences of the United States of America 20090224
Antibodies to myelin oligodendrocyte glycoprotein are not involved in the severity of chronic non-remitting experimental autoimmune encephalomyelitis. Immunology letters 20090221
Cytosine arabinoside-induced cytogenotoxicity in bone marrow and spermatogonial cells of mice and its potential transmission through the male germline. Mutation research 20090219
AID splice variants lack deaminase activity. Blood 20090219
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G. The EMBO journal 20090218
Mucosal immunization in macaques upregulates the innate APOBEC 3G anti-viral factor in CD4(+) memory T cells. Vaccine 20090205
Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis. Biochemistry 20090203
Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Biochemistry 20090203
Toward understanding the conformational dynamics of RNA ligation. Biochemistry 20090203
Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine. Cancer chemotherapy and pharmacology 20090201
Augmentation of antibody responses by retinoic acid and costimulatory molecules. Seminars in immunology 20090201
Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine. The Plant journal : for cell and molecular biology 20090201
Epigenetic mechanisms in mammals. Cellular and molecular life sciences : CMLS 20090201
Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemia. British journal of haematology 20090201
Evasion from CypA- and APOBEC-mediated restrictions is insufficient for HIV-1 to efficiently grow in simian cells. Microbes and infection 20090201
Molecular responses of Lotus japonicus to parasitism by the compatible species Orobanche aegyptiaca and the incompatible species Striga hermonthica. Journal of experimental botany 20090201
Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination. Autoimmunity 20090201
Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity. PLoS pathogens 20090201
Bacteroides induce higher IgA production than Lactobacillus by increasing activation-induced cytidine deaminase expression in B cells in murine Peyer's patches. Bioscience, biotechnology, and biochemistry 20090201
A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189. PLoS computational biology 20090201
Synthesis and hybridization properties of modified oligodeoxynucleotides carrying non-natural bases. Chemistry & biodiversity 20090201
Capecitabine, oxaliplatin and radiotherapy: a phase IB neoadjuvant study for esophageal cancer with gene expression analysis. Cancer investigation 20090201
Molecular evolution of a viral non-coding sequence under the selective pressure of amiRNA-mediated silencing. PLoS pathogens 20090201
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations. Oncogene 20090129
Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. Journal of the American Chemical Society 20090114
Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo. Journal of molecular biology 20090109
Expression and regulation of antiviral protein APOBEC3G in human neuronal cells. Journal of neuroimmunology 20090103
Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library. Life sciences 20090102
C-terminal half of HIV-1 Vif C possesses major determinant for APOBEC3G degradation. AIDS (London, England) 20090102
Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients. Lung cancer (Amsterdam, Netherlands) 20090101
Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis. Immunology 20090101
Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090101
A reliable confirmation of the chemical structure of synthetic oligonucleotides: detection of active protons in DNA oligomers by low-temperature FT infrared spectroscopy. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090101
Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090101
Interleukin-21 stimulates B-cell immunoglobulin E synthesis in human beings concomitantly with activation-induced cytidine deaminase expression and differentiation into plasma cells. Human immunology 20090101
Elite control of HIV infection: implications for vaccine design. Expert opinion on biological therapy 20090101
Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors. Pharmacogenomics 20090101
MDM2 is a novel E3 ligase for HIV-1 Vif. Retrovirology 20090101
A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation. PLoS genetics 20090101
Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. Molecular cancer therapeutics 20090101
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium. PLoS medicine 20090101
Autoimmune responses in the rheumatoid synovium. PLoS medicine 20090101
Novel exon of mammalian ADAR2 extends open reading frame. PloS one 20090101
Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G. PloS one 20090101
Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites. BMC genomics 20090101
APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA. Retrovirology 20090101
DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination. Advances in immunology 20090101
Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology. Journal of hematology & oncology 20090101
Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs. Veterinary research 20090101
APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression. Retrovirology 20090101
Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia. BMC cancer 20090101
Helicobacter pylori and gastric carcinogenesis. Journal of gastroenterology 20090101
Suppression of HIV-1 replication by microRNA effectors. Retrovirology 20090101
Folding machineries displayed on a cation-exchanger for the concerted refolding of cysteine- or proline-rich proteins. BMC biotechnology 20090101
Radiosynthesis of F-18 labeled cytidine analog 2'-fluoro-5-iodo-l-beta-d-arabinofuranosylcytosine ([(18)F]FIAC). Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090101
Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5. BMC biochemistry 20090101
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PloS one 20090101
A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR. Retrovirology 20090101
Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection. BMC cancer 20090101
High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity. Retrovirology 20090101
Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture. AIDS research and therapy 20090101
Basic science summary. Topics in HIV medicine : a publication of the International AIDS Society, USA 20090101
Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells. PloS one 20090101
CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection. PloS one 20090101
CURE-Chloroplast: a chloroplast C-to-U RNA editing predictor for seed plants. BMC bioinformatics 20090101
The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines. World journal of surgical oncology 20090101
High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer. PloS one 20090101
Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system. Molecular brain 20090101
Origin of saxitoxin biosynthetic genes in cyanobacteria. PloS one 20090101
Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA. Retrovirology 20090101
Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines. Journal of experimental & clinical cancer research : CR 20090101
[Uracil in DNA--friend or foe?]. Postepy biochemii 20090101
Clinical pharmacology and pharmacogenetics of gemcitabine. Drug metabolism reviews 20090101
Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3. BMC genomics 20090101
Gemcitabine sensitivity-related mRNA expression in endoscopic ultrasound-guided fine-needle aspiration biopsy of unresectable pancreatic cancer. Journal of experimental & clinical cancer research : CR 20090101
A method for identifying alternative or cryptic donor splice sites within gene and mRNA sequences. Comparisons among sequences from vertebrates, echinoderms and other groups. BMC genomics 20090101
Hydrogen bonding and packing density are factors most strongly connected to limiting sites of high flexibility in the 16S rRNA in the 30S ribosome. BMC structural biology 20090101
Pinellia ternata, Citrus reticulata, and their combinational prescription inhibit eosinophil infiltration and airway hyperresponsiveness by suppressing CCR3+ and Th2 cytokines production in the ovalbumin-induced asthma model. Mediators of inflammation 20090101
Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. PloS one 20090101
APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection. PloS one 20090101
Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif. Archives of virology 20090101
CAPIH: a Web interface for comparative analyses and visualization of host-HIV protein-protein interactions. BMC microbiology 20090101
Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents. Bioinorganic chemistry and applications 20090101
Identification of genes responsive to solar simulated UV radiation in human monocyte-derived dendritic cells. PloS one 20090101
Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo. PloS one 20090101
Resistance gene expression determines the in vitro chemosensitivity of non-small cell lung cancer (NSCLC). BMC cancer 20090101
[Mechanisms of interaction between HIV and Mycoplasma arginini in vitro]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20090101
Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance. Journal of translational medicine 20090101
Insulin gene expression is regulated by DNA methylation. PloS one 20090101
Structure and real-time monitoring of the enzymatic reaction of APOBEC3G which is involved in anti-HIV activity. Nucleic acids symposium series (2004) 20090101
Molecular mechanisms of apoptosis induced by 3'-ethynylcytidine. Nucleic acids symposium series (2004) 20090101
Human cellular restriction factors that target HIV-1 replication. BMC medicine 20090101
FGF4 independent derivation of trophoblast stem cells from the common vole. PloS one 20090101
ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics & chromatin 20090101
Different responses to two types of 5-fluorouracil prodrugs in combination with interferon-alpha in pulmonary metastases of renal cell carcinoma: a case report. Cases journal 20090101
Post-transcriptional control of chloroplast gene expression. Gene regulation and systems biology 20090101
Human APOBEC1 cytidine deaminase edits HBV DNA. Retrovirology 20090101
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions. BMC molecular biology 20090101
Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment. PloS one 20090101
Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization. Retrovirology 20090101
Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers. PloS one 20090101
The charge-transfer band of an oxidized watson-crick guanosine-cytidine complex. Angewandte Chemie (International ed. in English) 20090101
Azacitidine: a review of its use in higher-risk myelodysplastic syndromes/acute myeloid leukaemia. Drugs 20090101
Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells. Cerebrospinal fluid research 20090101
Tackling the methylome: recent methodological advances in genome-wide methylation profiling. Genome medicine 20090101
Assessment of Damage to Nucleic Acids and Repair Machinery in Salmonella typhimurium Exposed to Chlorine. International journal of microbiology 20090101
Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing. Frontiers in molecular neuroscience 20090101
Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae). BMC genetics 20090101
Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach. PloS one 20090101
Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage. Retrovirology 20090101
Ethnic differences of two non-synonymous single nucleotide polymorphisms in CDA gene. Drug metabolism and pharmacokinetics 20090101
A docking model of human ribonucleotide reductase with flavin and phenosafranine. Bioinformation 20090101
Targeting cancers in the gastrointestinal tract: role of capecitabine. OncoTargets and therapy 20090101
Gemcitabine for the treatment of advanced nonsmall cell lung cancer. OncoTargets and therapy 20090101
Ubiquitous antisense transcription in eukaryotes: novel regulatory mechanism or byproduct of opportunistic RNA polymerase? F1000 biology reports 20090101
The role of azacitidine in the management of myelodysplastic syndromes (MDS). Cancer management and research 20090101
Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model. International journal of tryptophan research : IJTR 20090101
DNA Cytosine demethylation: are we getting close? Cell 20081226
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 20081226
A conserved DYW domain of the pentatricopeptide repeat protein possesses a novel endoribonuclease activity. FEBS letters 20081224
Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression. International journal of cancer 20081215
Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20081215
Sequence variations in 185/333 messages from the purple sea urchin suggest posttranscriptional modifications to increase immune diversity. Journal of immunology (Baltimore, Md. : 1950) 20081215
Collateral damage from antigen receptor gene diversification. Cell 20081212
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 20081212
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell 20081212
Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine. Journal of medicinal chemistry 20081211
Quantitative analysis of the experimental cytotoxic drug cyclopentenyl cytosine and its metabolite in plasma with HPLC tandem mass spectrometry. Biomedical chromatography : BMC 20081201
Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine. Antiviral research 20081201
Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells. Blood 20081201
Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53. Drug metabolism and disposition: the biological fate of chemicals 20081201
Expression of activation-induced cytidine deaminase in malignant lymphomas infiltrating the bone marrow. Applied immunohistochemistry & molecular morphology : AIMM 20081201
Novel targets for HIV therapy. Antiviral research 20081201
Effect of acetylcholine precursors on proliferation and differentiation of astroglial cells in primary cultures. Neurochemical research 20081201
Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha. Trends in microbiology 20081201
Ground state, intermediate, and multivalent nucleotide analogue inhibitors of cytidine 5'-triphosphate synthase. ChemMedChem 20081201
Study on disulfur-backboned nucleic acids: part 3. Efficient synthesis of 3',5'-dithio-2'-deoxyuridine and deoxycytidine. Nucleosides, nucleotides & nucleic acids 20081201
An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cells. Journal of immunology (Baltimore, Md. : 1950) 20081201
Online immobilized metal affinity chromatography/mass spectrometric analysis of changes elicited by cCMP in the murine brain phosphoproteome. Rapid communications in mass spectrometry : RCM 20081201
Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate. Chemical & pharmaceutical bulletin 20081201
Candidate new species of Kobuvirus in porcine hosts. Emerging infectious diseases 20081201
APOBEC3G inhibits elongation of HIV-1 reverse transcripts. PLoS pathogens 20081201
Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway. PLoS genetics 20081201
Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine. International journal of nanomedicine 20081201
APOBEC3G subunits self-associate via the C-terminal deaminase domain. The Journal of biological chemistry 20081128
Effect of the cyclobutane cytidine dimer on the properties of Escherichia coli DNA photolyase. The journal of physical chemistry. B 20081127
Effects of cytidine 5'-diphosphocholine (CDP-choline) on the thermal nociceptive threshold in streptozotocin-induced diabetic mice. European journal of pharmacology 20081119
Self-assembly of a chiral carbonate- and cytidine-containing dodecanuclear copper(II) complex: a multiarm-supplied globular capsule. Inorganic chemistry 20081117
Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration. The Journal of biological chemistry 20081114
Identification and characterization of the nuclear isoform of Drosophila melanogaster CTP:phosphocholine cytidylyltransferase. Biochemistry 20081111
Length of the hypermutation motif DGYW/WRCH in the focus of statistical limits. Implications for a double-motif or extended motif recognition models. Journal of theoretical biology 20081107
Furanose dynamics in the HhaI methyltransferase target DNA studied by solution and solid-state NMR relaxation. The journal of physical chemistry. B 20081106
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature 20081106
AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Molecular immunology 20081101
Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo. Journal of virology 20081101
Single-strand DNA breaks in Ig class switch recombination that depend on UNG but not AID. International immunology 20081101
Squalenoyl nanomedicine of gemcitabine is more potent after oral administration in leukemia-bearing rats: study of mechanisms. Anti-cancer drugs 20081101
Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif. Nature structural & molecular biology 20081101
Update on antiviral treatment of adenoviral ocular infections. American journal of ophthalmology 20081101
Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway. PLoS pathogens 20081101
Small RNAs with 5'-polyphosphate termini associate with a Piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica. PLoS pathogens 20081101
Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase. Molecular cell 20081024
A systems biology analysis of protein-protein interactions in the APOBEC family. Life sciences 20081010
Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability. Molecular pharmaceutics 20081006
Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil. Investigational new drugs 20081001
The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab. Leukemia 20081001
Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences. Arteriosclerosis, thrombosis, and vascular biology 20081001
Characteristics and prediction of RNA editing sites in transcripts of the Moss Takakia lepidozioides chloroplast. DNA research : an international journal for rapid publication of reports on genes and genomes 20081001
The 9-1-1 DNA clamp is required for immunoglobulin gene conversion. Molecular and cellular biology 20081001
Bacterial CMP-sialic acid synthetases: production, properties, and applications. Applied microbiology and biotechnology 20081001
Pyrrolo-C as a molecular probe for monitoring conformations of the tRNA 3' end. RNA (New York, N.Y.) 20081001
Conformational preferences of hypermodified nucleoside lysidine (k2C) occurring at 'wobble' position in anticodon loop of tRNA(Ile). Nucleosides, nucleotides & nucleic acids 20081001
Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues. Bioorganic & medicinal chemistry 20081001
Small-molecule inhibition of HIV-1 Vif. Nature biotechnology 20081001
Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase. Nature structural & molecular biology 20081001
Enhancing immunity to HIV through APOBEC. Nature biotechnology 20081001
The level of APOBEC3G (hA3G)-related G-to-A mutations does not correlate with viral load in HIV type 1-infected individuals. AIDS research and human retroviruses 20081001
Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5alpha proteins. PLoS pathogens 20081001
Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress. PLoS genetics 20081001
Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production. The Journal of allergy and clinical immunology 20081001
APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages. Virology 20080930
miR-181b negatively regulates activation-induced cytidine deaminase in B cells. The Journal of experimental medicine 20080929
Functional domain organization of human APOBEC3G. Virology 20080915
Characterization of conserved motifs in HIV-1 Vif required for APOBEC3G and APOBEC3F interaction. Journal of molecular biology 20080912
Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science (New York, N.Y.) 20080905
Regulating antibody diversity: taming a mutagen. Molecular cell 20080905
Kinetics and activation parameter analysis for the prebiotic oligocytidylate formation on Na(+)-montmorillonite at 0-100 degrees C. The journal of physical chemistry. A 20080904
Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer. British journal of cancer 20080902
Polymorphism C3435T of the MDR1 gene in Central Americans and Spaniards. Molecular biology reports 20080901
Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. Glycobiology 20080901
S(mu) mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells. Blood 20080901
Central choline suppresses plasma renin response to graded haemorrhage in rats. Clinical and experimental pharmacology & physiology 20080901
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Human molecular genetics 20080901
A pilot pharmacokinetic study of oral azacitidine. Leukemia 20080901
Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics. Drug metabolism and disposition: the biological fate of chemicals 20080901
Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences. Journal of virology 20080901
Hypermutation of an ancient human retrovirus by APOBEC3G. Journal of virology 20080901
Role of phosphatidylglycerol in the function and assembly of Photosystem II reaction center, studied in a cdsA-inactivated PAL mutant strain of Synechocystis sp. PCC6803 that lacks phycobilisomes. Biochimica et biophysica acta 20080901
Absence of H186R polymorphism in exon 4 of the APOBEC3G gene among North Indian individuals. Genetic testing 20080901
Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology 20080901
Inflammation and cancer: is AID aiding? Gastroenterology 20080901
[Quantitative analysis of nucleotide mixtures with terahertz time domain spectroscopy]. Guang pu xue yu guang pu fen xi = Guang pu 20080901
Cancer prevention: epigenetics steps up to the plate. Cancer prevention research (Philadelphia, Pa.) 20080901
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer prevention research (Philadelphia, Pa.) 20080901
Historical survey on chromatoid body research. Acta histochemica et cytochemica 20080828
Determination of nucleotides in infant formula by ion-exchange liquid chromatography. Journal of agricultural and food chemistry 20080827
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Molecular cell 20080822
A new entry to carbocyclic nucleosides: oxidative coupling reaction of cycloalkenylsilanes with a nucleobase mediated by hypervalent iodine reagent. Organic letters 20080821
The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon. The EMBO journal 20080820
The incorporation of APOBEC3 proteins into murine leukemia viruses. Virology 20080815
Relationship between human immunodeficiency type 1 infection and expression of human APOBEC3G and APOBEC3F. The Journal of infectious diseases 20080815
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 20080815
Cytidine-5-diphosphocholine supplement in early life induces stable increase in dendritic complexity of neurons in the somatosensory cortex of adult rats. Neuroscience 20080813
AID and RAG1 do not contribute to lymphomagenesis in Emu c-myc transgenic mice. Oncogene 20080807
Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines. Journal of the American Chemical Society 20080806
Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice. Cancer chemotherapy and pharmacology 20080801
Conserved and non-conserved features of HIV-1 and SIVagm Vif mediated suppression of APOBEC3 cytidine deaminases. Cellular microbiology 20080801
Effects of prenatal tobacco exposure on gene expression profiling in umbilical cord tissue. Pediatric research 20080801
Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1). Journal of cellular physiology 20080801
The iscS gene deficiency affects the expression of pyrimidine metabolism genes. Biochemical and biophysical research communications 20080801
Dihydropyrimidine dehydrogenases and cytidine-deaminase gene polymorphisms as outcome predictors in resected gastric cancer patients treated with fluoropyrimidine adjuvant chemotherapy. Journal of surgical oncology 20080801
Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C. Hepatology (Baltimore, Md.) 20080801
Mass spectrometry of protein-ligand complexes: enhanced gas-phase stability of ribonuclease-nucleotide complexes. Journal of the American Society for Mass Spectrometry 20080801
R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin. Hepatology (Baltimore, Md.) 20080801
Hepatic lipase gene -514C/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations. Lipids 20080801
Identification of initiator B cells, a novel subset of activation-induced deaminase-dependent B-1-like cells that mediate initiation of contact sensitivity. Journal of immunology (Baltimore, Md. : 1950) 20080801
13C relaxation studies of the DNA target sequence for hhai methyltransferase reveal unique motional properties. Biochemistry 20080722
Stereoselective synthesis of 4'-selenonucleosides using the Pummerer glycosylation reaction. Carbohydrate research 20080721
Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C. Virology 20080720
The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation. Virology 20080720
Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase. Journal of immunology (Baltimore, Md. : 1950) 20080715
Artificial DNA made exclusively of nonnatural C-nucleosides with four types of nonnatural bases. Journal of the American Chemical Society 20080709
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU). Cancer chemotherapy and pharmacology 20080701
Optimized blood sampling with cytidine deaminase inhibitor for improved analysis of capecitabine metabolites. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080701
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. Journal of immunology (Baltimore, Md. : 1950) 20080701
Induction of nucleoside phosphorylase in Enterobacter aerogenes and enzymatic synthesis of adenine arabinoside. Journal of Zhejiang University. Science. B 20080701
APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication. PLoS pathogens 20080701
Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability. Drug development and industrial pharmacy 20080701
Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure. Environmental health perspectives 20080701
[Ethnic differences of genetic polymorphisms in cancer chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy 20080701
[The associations between polymorphisms of APOBEC3G and different outcomes of persistent HBV infection]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080701
[Advances in the study of molecular mechanism of APOBEC3G anti-HIV-1]. Yao xue xue bao = Acta pharmaceutica Sinica 20080701
[Study on the relationship between human cytidine deaminase gene polymorphisms and Ara-C sensitivity]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20080701
Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase. The Journal of biological chemistry 20080620
Variable contexts and levels of hypermutation in HIV-1 proviral genomes recovered from primary peripheral blood mononuclear cells. Virology 20080620
The emerging role of innate immunity in protection against HIV-1 infection. Vaccine 20080606
Not just sheer luck! Immune correlates of protection against HIV-1 infection. Vaccine 20080606
Bisphosphonate derivatives of nucleoside antimetabolites: hydrolytic stability and hydroxyapatite adsorption of 5'-beta,gamma-methylene and 5'-beta,gamma-(1-hydroxyethylidene) triphosphates of 5-fluorouridine and ara-cytidine. The Journal of organic chemistry 20080606
Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G. Current biology : CB 20080603
APOBEC3 proteins and reverse transcription. Virus research 20080601
Associations between cigarette smoking and mitochondrial DNA abnormalities in buccal cells. Carcinogenesis 20080601
Acid-base and metal ion binding properties of 2-thiocytidine in aqueous solution. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601
Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients. The Journal of antimicrobial chemotherapy 20080601
Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins. Journal of virology 20080601
Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery. The FEBS journal 20080601
Clonal relationship between infiltrating immunoglobulin G4 (IgG4)-positive plasma cells in lacrimal glands and circulating IgG4-positive lymphocytes in Mikulicz's disease. Clinical and experimental immunology 20080601
Nucleoside composition of Heloderma venoms. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601
Biosynthesis of the Escherichia coli K1 group 2 polysialic acid capsule occurs within a protected cytoplasmic compartment. Molecular microbiology 20080601
Hepatitis B: modern concepts in pathogenesis--APOBEC3 cytidine deaminases as effectors in innate immunity against the hepatitis B virus. Current opinion in infectious diseases 20080601
Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation. RNA (New York, N.Y.) 20080601
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis. Current opinion in lipidology 20080601
Interactions of nucleosides with CrO(4) (2-) and Cr(3+) as studied by electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM 20080601
Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080601
Modulation of gemcitabine (2',2'-difluoro-2'-deoxycytidine) pharmacokinetics, metabolism, and bioavailability in mice by 3,4,5,6-tetrahydrouridine. Clinical cancer research : an official journal of the American Association for Cancer Research 20080601
Patterns of evolution and host gene mimicry in influenza and other RNA viruses. PLoS pathogens 20080601
Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias. Current medicinal chemistry 20080601
The B cell antigen receptor and overexpression of MYC can cooperate in the genesis of B cell lymphomas. PLoS biology 20080601
Correlation between cytidine deaminase genotype and gemcitabine deamination in blood samples. Nucleosides, nucleotides & nucleic acids 20080601
Key labeling technologies to tackle sizeable problems in RNA structural biology. International journal of molecular sciences 20080601
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells. Virology 20080525
A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV. The Journal of biological chemistry 20080516
Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli. The Biochemical journal 20080515
Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution. Proteins 20080515
APOBEC3G is degraded by the proteasomal pathway in a Vif-dependent manner without being polyubiquitylated. The Journal of biological chemistry 20080509
Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence. The Journal of biological chemistry 20080509
Antitumoral activity of PEG-gemcitabine prodrugs targeted by folic acid. Journal of controlled release : official journal of the Controlled Release Society 20080508
Profiling of differentially expressed genes in porcine epithelial cells derived from periodontal ligament and gingiva by DNA microarray. Archives of oral biology 20080501
Human APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1. Journal of virology 20080501
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors. Antimicrobial agents and chemotherapy 20080501
Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv. Journal of molecular modeling 20080501
Reflections on the state of play in somatic hypermutation. Molecular immunology 20080501
Confirmation of the chromosome damaging effects of lamivudine in in vitro human peripheral blood lymphocytes. Environmental and molecular mutagenesis 20080501
Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H. The Journal of general virology 20080501
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. Immunity 20080501
Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction. PLoS pathogens 20080501
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity 20080501
A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression. Current drug metabolism 20080501
Along came a spider: AID escapes a microRNA web. Immunity 20080501
APOBEC3 proteins and porcine endogenous retroviruses. Transplantation proceedings 20080501
Human cytidine deaminase APOBEC3H restricts HIV-1 replication. The Journal of biological chemistry 20080425
Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. Journal of immunology (Baltimore, Md. : 1950) 20080415
Comprehensive genetic and epigenetic analysis of occult hepatitis B from liver tissue samples. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080415
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors. European journal of pharmacology 20080414
Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions. Science (New York, N.Y.) 20080411
Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells. British journal of cancer 20080408
Exogenous nucleosides accelerate differentiation of rat intestinal epithelial cells. The British journal of nutrition 20080401
AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene. Molecular immunology 20080401
Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney. Molecular immunology 20080401
PI3K is a negative regulator of IgE production. International immunology 20080401
A memoir of AID, which engraves antibody memory on DNA. Nature immunology 20080401
Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus--biochemical characterization and homology modeling. The FEBS journal 20080401
Vif and Apobec3G in the innate immune response to HIV: a tale of two proteins. Future microbiology 20080401
Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. Leukemia & lymphoma 20080401
A splenic marginal zone-like peripheral blood CD27+B220- B cell population is preferentially depleted in HIV type 1-infected individuals. AIDS research and human retroviruses 20080401
The role of DNA hypermethylation and demethylation in cancer and cancer therapy. Current oncology (Toronto, Ont.) 20080401
Evolution, development, mechanism and function of IgA in the gut. Current opinion in immunology 20080401
[The assay of intracelluar cytidine deaminase activity and its clinical significance in patient with acute leukemia]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20080401
'One pill, once daily': what clinicians need to know about Atriplatrade mark. Therapeutics and clinical risk management 20080401
[Study on the difference of the APOBEC3G mRNA levels among HIV long-term nonprogressors, slow progressors, people at high risks and normal people]. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20080401
[Relationship between the expression of the genes encoding the key enzymes for cytarabine metabolism and the pharmacokinetics of cytarabine in the treatment of childhood acute leukemia with high-dose cytarabine]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20080401
DNA-labelled cytidine assay for the quantification of CAG repeats. Journal of neuroscience methods 20080330
Sequence editing by Apolipoprotein B RNA-editing catalytic component [corrected] and epidemiological surveillance of transmitted HIV-1 drug resistance. AIDS (London, England) 20080330
Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding. The Journal of biological chemistry 20080321
Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase. The Journal of biological chemistry 20080321
High-performance liquid chromatography determination of 5-methyl-2'-deoxycytidine, 2'-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests. Analytical biochemistry 20080315
Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research 20080315
Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+. Journal of molecular biology 20080314
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G. Nature 20080306
Identification of somatic hypermutations in the TP53 gene in B-cell chronic lymphocytic leukemia. Molecular immunology 20080301
Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion. Molecular immunology 20080301
Germinal center B-cell-associated DNA hypomethylation at transcriptional regions of the AID gene. Molecular immunology 20080301
HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes. Virology 20080301
Simultaneous analysis of microbial identity and function using NanoSIMS. Environmental microbiology 20080301
Is AID a monomer in solution? DNA repair 20080301
Conjugation of (E)-5-[2-(Methoxycarbonyl)ethenyl]cytidine to hydrophilic microspheres: development of a mobile microscale UV light actinometer. Bioconjugate chemistry 20080301
APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells. The Journal of general virology 20080301
Enhanced NMR signal detection of imino protons in RNA molecules containing 3' dangling nucleotides. Journal of biomolecular NMR 20080301
Mechanisms for decreased function of B cells in aged mice and humans. Journal of immunology (Baltimore, Md. : 1950) 20080301
Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferase. Yeast (Chichester, England) 20080301
RNA editing in the anticodon of tRNA Leu (CAA) occurs before group I intron splicing in plastids of a moss Takakia lepidozioides S. Hatt. & Inoue. Plant biology (Stuttgart, Germany) 20080301
Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma. Hepatology (Baltimore, Md.) 20080301
Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy. Mini reviews in medicinal chemistry 20080301
GADD45A does not promote DNA demethylation. PLoS genetics 20080301
Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography. International journal of molecular sciences 20080301
The epigenetic origin of aneuploidy. Current genomics 20080301
Transition state structure of E. coli tRNA-specific adenosine deaminase. Journal of the American Chemical Society 20080227
Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215
Comment on 'Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjogren's syndrome'. Journal of immunology (Baltimore, Md. : 1950) 20080215
Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus. Journal of immunology (Baltimore, Md. : 1950) 20080215
Two levels of protection for the B cell genome during somatic hypermutation. Nature 20080214
Synthesis and antiviral activities of amide derivatives containing the alpha-aminophosphonate moiety. Journal of agricultural and food chemistry 20080213
Distribution of nucleosides and nucleobases in edible fungi. Journal of agricultural and food chemistry 20080213
Will cyclopentenyl cytosine (CPEC) ever have a future in the clinic? Leukemia research 20080201
Ternary borate-nucleoside complex stabilization by ribonuclease A demonstrates phosphate mimicry. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201
Pathways of pyrimidine salvage in Pseudomonas and former Pseudomonas: detection of recycling enzymes using high-performance liquid chromatography. Current microbiology 20080201
Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA repair 20080201
Vpr.A3A chimera inhibits HIV replication. The Journal of biological chemistry 20080201
The pyrimidin analogue cyclopentenyl cytosine induces alloantigen-specific non-responsiveness of human T lymphocytes. Clinical and experimental immunology 20080201
Antibody diversification by somatic mutation: from Burnet onwards. Immunology and cell biology 20080201
Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion. International immunology 20080201
Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase. Nucleosides, nucleotides & nucleic acids 20080201
Pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in healthy volunteers treated with trimethoprim-sulphamethoxazole. Journal of clinical pharmacy and therapeutics 20080201
The 262T>C silent mutation of the platelet beta 3-integrin gene is not restricted to a single family. Transfusion 20080201
Modeling multiple myeloma by AID-dependent conditional activation of MYC. Cancer cell 20080201
AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies. Cancer cell 20080201
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS pathogens 20080201
Nucleotide biosynthesis is critical for growth of bacteria in human blood. PLoS pathogens 20080201
[Enhanced protein production of Vif and APOBEC3G by HIV-1 Vpr]. Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20080201
Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar. BMB reports 20080131
A phase II study of paclitaxel and capecitabine as a first-line combination chemotherapy for advanced gastric cancer. British journal of cancer 20080129
2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups. The Journal of biological chemistry 20080125
Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax. The Journal of biological chemistry 20080125
Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging. Journal of molecular biology 20080125
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA. Journal of molecular biology 20080125
Peripheral administration of CDP-choline and its cholinergic metabolites increases serum insulin: muscarinic and nicotinic acetylcholine receptors are both involved in their actions. Neuroscience letters 20080124
Synthesis and characterization of poly(2-ethyl 2-oxazoline)-conjugates with proteins and drugs: suitable alternatives to PEG-conjugates? Journal of controlled release : official journal of the Controlled Release Society 20080122
Synthesis and characterization of the 5-methyl-2'-deoxycytidine glycol-dioxoosmium-bipyridine ternary complex in DNA. Organic & biomolecular chemistry 20080121
Characterization of reproduction-specific genes in a marine bivalve mollusc: influence of maturation stage and sex on mRNA expression. Gene 20080115
CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. Journal of immunology (Baltimore, Md. : 1950) 20080115
Novel blood-based, five-gene biomarker set for the detection of colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20080115
Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products. Biochemistry 20080108
Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation. Virology 20080105
Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080102
Molecular genetic analysis of Hungarian patients with the hyper-immunoglobulin M syndrome. Molecular immunology 20080101
Modulation of human cytidine deaminase by specific aminoacids involved in the intersubunit interactions. Proteins 20080101
Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression. Cellular microbiology 20080101
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA repair 20080101
Compartmentalization of non-adenine nucleotides in anoxic cardiac myocytes. Basic research in cardiology 20080101
B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE. The Journal of allergy and clinical immunology 20080101
Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation? American journal of physiology. Gastrointestinal and liver physiology 20080101
Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis. ChemMedChem 20080101
AID is required for germinal center-derived lymphomagenesis. Nature genetics 20080101
The extent of DNA deformation in DNA photolyase-substrate complexes: a solution state fluorescence study. Photochemistry and photobiology 20080101
Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells. Breast cancer research : BCR 20080101
Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells. Biological & pharmaceutical bulletin 20080101
Protocol for nearly full-length sequencing of HIV-1 RNA from plasma. PloS one 20080101
Cyclic tetranuclear half-sandwich ruthenium(II) complexes with 4,7-phenanthroline and hydroxo bridges: crystal structure, solution behaviour and binding to nucleosides. Journal of inorganic biochemistry 20080101
Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Ectopic expression of AID in a non-B cell line triggers A:T and G:C point mutations in non-replicating episomal vectors. PloS one 20080101
Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. PLoS genetics 20080101
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations. Autonomic & autacoid pharmacology 20080101
Solubility enhancement of aggregation-prone heterologous proteins by fusion expression using stress-responsive Escherichia coli protein, RpoS. BMC biotechnology 20080101
Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction. Current medicinal chemistry 20080101
Cyclic, trinuclear PdII complex of cytidine with pronounced double cone structure. Journal of inorganic biochemistry 20080101
6th international symposium on retroviral nucleocapsid. Retrovirology 20080101
Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection. PloS one 20080101
The biochemistry of somatic hypermutation. Annual review of immunology 20080101
The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annual review of immunology 20080101
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes. Genome biology 20080101
The process of RNA editing in plant mitochondria. Mitochondrion 20080101
Aberrant AID expression and human cancer development. The international journal of biochemistry & cell biology 20080101
Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3). Retrovirology 20080101
Mechanism and regulation of class switch recombination. Annual review of immunology 20080101
A generic approach to identify Transcription Factor-specific operator motifs; Inferences for LacI-family mediated regulation in Lactobacillus plantarum WCFS1. BMC genomics 20080101
Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets. BMC bioinformatics 20080101
Vpr14-88-Apobec3G fusion protein is efficiently incorporated into Vif-positive HIV-1 particles and inhibits viral infection. PloS one 20080101
Separation of cytidine 5'-triphosphate biosynthesized from cytidine 5'-monophosphate on ion-exchange resin and HPLC analysis of cytidine compounds. Applied biochemistry and biotechnology 20080101
Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier. BMC cancer 20080101
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer. BMC cancer 20080101
High-throughput synthesis of HepDirect prodrugs of nucleoside monophosphates. Journal of combinatorial chemistry 20080101
Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1). PloS one 20080101
Quantitative effect of suboptimal codon usage on translational efficiency of mRNA encoding HIV-1 gag in intact T cells. PloS one 20080101
Uracil within DNA: an actor of antiviral immunity. Retrovirology 20080101
Anticancer drug discovery targeting DNA hypermethylation. Current medicinal chemistry 20080101
Genotyping panel for assessing response to cancer chemotherapy. BMC medical genomics 20080101
Isolation and characterization of side population stem cells in articular synovial tissue. BMC musculoskeletal disorders 20080101
HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells. PloS one 20080101
A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation. PloS one 20080101
A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans. PloS one 20080101
HIV-1 Vif, APOBEC, and intrinsic immunity. Retrovirology 20080101
Characterization of APOBEC3G binding to 7SL RNA. Retrovirology 20080101
APOBEC3G encapsidation into HIV-1 virions: which RNA is it? Retrovirology 20080101
The AID/APOBEC family of nucleic acid mutators. Genome biology 20080101
Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F. Microbes and infection 20080101
Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system. Antiviral chemistry & chemotherapy 20080101
Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration. Retrovirology 20080101
Implication of TRIM alpha and TRIMCyp in interferon-induced anti-retroviral restriction activities. Retrovirology 20080101
The Role of PPAR-gamma and Its Interaction with COX-2 in Pancreatic Cancer. PPAR research 20080101
Replication potentials of vif variant viruses generated from monkey cell-tropic HIV-1 derivative clones NL-DT5/NL-DT5R. Microbes and infection 20080101
Host restriction factors blocking retroviral replication. Annual review of genetics 20080101
Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures. PloS one 20080101
MSDmotif: exploring protein sites and motifs. BMC bioinformatics 20080101
Demonstration of a novel HIV-1 restriction phenotype from a human T cell line. PloS one 20080101
Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code. PloS one 20080101
APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication. Retrovirology 20080101
Complexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate. Bioinorganic chemistry and applications 20080101
Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562. BMC genomics 20080101
Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo 'traces' on the murine IAPE and human HERV-K elements. Retrovirology 20080101
Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate. BMC genomics 20080101
Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease. PloS one 20080101
A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes. Virology journal 20080101
NMR assignments and the identification of the secondary structure of the anti-retroviral cytidine deaminase. Nucleic acids symposium series (2004) 20080101
2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography. Nucleic acids symposium series (2004) 20080101
Synthesis and properties of 2'-modified-4'-thioRNA. Nucleic acids symposium series (2004) 20080101
Synthesis and properties of oligonucleotides containing 4'-selenoribonucleosides. Nucleic acids symposium series (2004) 20080101
Design of an ultimate quencher free molecular beacon containing pyrrolocytidine-guanine base pair. Nucleic acids symposium series (2004) 20080101
Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity. Nucleic acids symposium series (2004) 20080101
RNA containing pyrrolocytidine base analogs: increased binding affinity and fluorescence that responds to hybridization. Nucleic acids symposium series (2004) 20080101
RNA containing pyrrolocytidine base analogs: good binding affinity and fluorescence that responds to hybridization. Nucleic acids symposium series (2004) 20080101
Total syntheses of a North methanocarba puromycin analog and its dinucleotide derivative. Nucleic acids symposium series (2004) 20080101
Synthesis and antiviral activity of novel derivatives of 2'-beta-C-methylcytidine. Nucleic acids symposium series (2004) 20080101
In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine. Nucleic acids symposium series (2004) 20080101
Synthesis of conformationally locked carbocyclic 1,3-diazepinone nucleosides as inhibitors of cytidine deaminase. Nucleic acids symposium series (2004) 20080101
RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes. BMC genomics 20080101
Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift? Biology direct 20080101
DNA damage in preserved specimens and tissue samples: a molecular assessment. Frontiers in zoology 20080101
The epigenetics of cancer in children. Klinische Padiatrie 20080101
High-fidelity correction of genomic uracil by human mismatch repair activities. BMC molecular biology 20080101
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum. BMC genomics 20080101
Gender differences in genetic risk profiles for cardiovascular disease. PloS one 20080101
Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3. International journal of biological sciences 20080101
25 years of HIV-1 research - progress and perspectives. BMC medicine 20080101
Antitumor efficacy of combination of interferon-gamma-inducible protein 10 gene with gemcitabine, a study in murine model. Journal of experimental & clinical cancer research : CR 20080101
Apobec 3F and apobec 3G have no inhibition and hypermutation effect on the human influenza A virus. Acta virologica 20080101
The ubiquitin system, disease, and drug discovery. BMC biochemistry 20080101
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals. BMC molecular biology 20080101
Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype. Journal of ovarian research 20080101
Macronuclear genome structure of the ciliate Nyctotherus ovalis: single-gene chromosomes and tiny introns. BMC genomics 20080101
Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo. PloS one 20080101
Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins. PloS one 20080101
Future treatment options for HCV: double, triple, what is the optimal combination? Best practice & research. Clinical gastroenterology 20080101
Molecular analysis of activation-induced cytidine deaminase gene in immunoglobulin-E deficient patients. Clinical & developmental immunology 20080101
Gene expression in Pre-MBT embryos and activation of maternally-inherited program of apoptosis to be executed at around MBT as a fail-safe mechanism in Xenopus early embryogenesis. Gene regulation and systems biology 20080101
Inhibition of DNA methylation is involved in transdifferentiation of myoblasts into smooth muscle cells. Molecules and cells 20071231
Biomimetic aminoacylation of ribonucleotides and RNA with aminoacyl phosphate esters and lanthanum salts. Journal of the American Chemical Society 20071226
Cardiovascular effects of CDP-choline and its metabolites: involvement of peripheral autonomic nervous system. European journal of pharmacology 20071222
Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc. The Journal of biological chemistry 20071221
Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif. Virology 20071220
Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice. Journal of the American College of Cardiology 20071211
CD45RO enriches for activated, highly mutated human germinal center B cells. Blood 20071201
Oncogenic events triggered by AID, the adverse effect of antibody diversification. Carcinogenesis 20071201
Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma. Hepatology (Baltimore, Md.) 20071201
Transport proteins PotD and Crr of Escherichia coli, novel fusion partners for heterologous protein expression. Biochimica et biophysica acta 20071201
Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma. International journal of oncology 20071201
Effects of point mutations in the cytidine deaminase domains of APOBEC3B on replication and hypermutation of hepatitis B virus in vitro. The Journal of general virology 20071201
Activation-induced cytidine deaminase induces DNA break repair events more frequently in the Ig switch region than other sites in the mammalian genome. European journal of immunology 20071201
Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome. Clinical cancer research : an official journal of the American Association for Cancer Research 20071201
[Single-nucleotide polymorphisms of the cytidine deaminase gene in childhood with acute leukemia and normal Chinese children]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20071201
Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine. Structure (London, England : 1993) 20071201
Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PLoS pathogens 20071201
Rates of spontaneous disintegration of DNA and the rate enhancements produced by DNA glycosylases and deaminases. Biochemistry 20071127
Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G) and its family members. The Journal of biological chemistry 20071116
Differentiation and Ig-allele switch in cell line WEHI-231. Journal of immunology (Baltimore, Md. : 1950) 20071115
Spontaneous class switch recombination in B cell lymphopoiesis generates aberrant switch junctions and is increased after VDJ rearrangement. Journal of immunology (Baltimore, Md. : 1950) 20071115
Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development. Journal of immunology (Baltimore, Md. : 1950) 20071115
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation. Journal of immunology (Baltimore, Md. : 1950) 20071115
Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis. AIDS (London, England) 20071112
Conditional intestinal lipotoxicity in Apobec-1-/- Mttp-IKO mice: a survival advantage for mammalian intestinal apolipoprotein B mRNA editing. The Journal of biological chemistry 20071109
Low dose Zebularine treatment enhances immunogenicity of tumor cells. Cancer letters 20071108
Phototriggers for nucleobases with improved photochemical properties. Organic letters 20071108
APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription. The Journal of biological chemistry 20071102
Limited antitumor-effect associated with toxicity of the experimental cytotoxic drug cyclopentenyl cytosine in NOD/scid mice with acute lymphoblastic leukemia. Leukemia research 20071101
Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity. Proteins 20071101
Cytidine deamination assay to differentiate Staphylococcus aureus from other staphylococci. Letters in applied microbiology 20071101
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine. International journal of oncology 20071101
High rate of starvation-associated mutagenesis in Ung(-) yeast caused by the overproduction of human activation-induced deaminase. Current genetics 20071101
Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. Journal of immunology (Baltimore, Md. : 1950) 20071101
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase. Immunity 20071101
T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS pathogens 20071101
[Prediction of adverse drug reactions based on genomic information]. Nihon rinsho. Japanese journal of clinical medicine 20071028
Characterization of a novel Cullin5 binding domain in HIV-1 Vif. Journal of molecular biology 20071026
The interferon-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous system. Virology 20071025
Solid-phase synthesis of symmetrical 5',5'-dinucleoside mono-, di-, tri-, and tetraphosphodiesters. Organic letters 20071025
Genotype-based methods for anticipating gemcitabine-related severe toxicities may lead to false-negative results. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020
Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. Journal of immunology (Baltimore, Md. : 1950) 20071015
Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. Journal of molecular biology 20071005
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 20071004
Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G. FEBS letters 20071002
Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells. Antiviral research 20071001
Spectroscopic and molecular modeling studies of the interaction between cytidine and human serum albumin and its analytical application. Biopolymers 20071001
Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. The Journal of allergy and clinical immunology 20071001
Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides. Cancer science 20071001
Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome. Journal of immunology (Baltimore, Md. : 1950) 20071001
Chromatin structure regulates gene conversion. PLoS biology 20071001
Toxic death case in a patient undergoing gemcitabine-based chemotherapy in relation with cytidine deaminase downregulation. Pharmacogenetics and genomics 20071001
The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G. Biochimica et biophysica acta 20071001
Nicotinamide riboside kinase structures reveal new pathways to NAD+. PLoS biology 20071001
Increased APOBEC3G expression is associated with extensive G-to-A hypermutation in viral DNA in rhesus macaque brain during lentiviral infection. Journal of neuropathology and experimental neurology 20071001
Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1. PLoS pathogens 20071001
Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses. PLoS genetics 20071001
Estimating the relative contribution of dNTP pool imbalance and APOBEC3G/3F editing to HIV evolution in vivo. Journal of computational biology : a journal of computational molecular cell biology 20071001
[Vertebrate immunity: mutator proteins and their evolution]. Genetika 20071001
IL-4-induced AID expression and its relevance to IgA class switch recombination. Biochemical and biophysical research communications 20070921
Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice. Cancer research 20070915
Fast simultaneous determination of 14 nucleosides and nucleobases in cultured Cordyceps using ultra-performance liquid chromatography. Talanta 20070915
Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases. Biochemistry 20070911
RNA and DNA binding properties of HIV-1 Vif protein: a fluorescence study. The Journal of biological chemistry 20070907
A hypothesis on the identification of the editing enzyme in plant organelles. FEBS letters 20070904
Computational analysis of RNA editing sites in plant mitochondrial genomes reveals similar information content and a sporadic distribution of editing sites. Molecular biology and evolution 20070901
Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C. Hepatology (Baltimore, Md.) 20070901
Frequent occurrence of B-cell lymphomas in angioimmunoblastic T-cell lymphoma and proliferation of Epstein-Barr virus-infected cells in early cases. British journal of haematology 20070901
Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. British journal of haematology 20070901
Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease. Liver international : official journal of the International Association for the Study of the Liver 20070901
5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo. Cancer research 20070901
T cells contain an RNase-insensitive inhibitor of APOBEC3G deaminase activity. PLoS pathogens 20070901
Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates. The Journal of biological chemistry 20070831
Strand-biased spreading of mutations during somatic hypermutation. Science (New York, N.Y.) 20070831
Antiproliferative effects of sapacitabine (CYC682), a novel 2'-deoxycytidine-derivative, in human cancer cells. British journal of cancer 20070828
Intrinsic electrophilic properties of nucleosides: photoelectron spectroscopy of their parent anions. The Journal of chemical physics 20070828
Ab initio ONIOM-molecular dynamics (MD) study on the deamination reaction by cytidine deaminase. The journal of physical chemistry. B 20070823
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling. Oncogene 20070816
Direct detection of ligand binding to Sepharose-immobilised protein using saturation transfer double difference (STDD) NMR spectroscopy. Biochemical and biophysical research communications 20070810
Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets. The British journal of nutrition 20070801
The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains. Virology 20070801
Incorporation of two modified nucleosides allows selective platination of an oligonucleotide making it suitable for duplex cross-linking. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801
Ultrafast electronic relaxation in guanosine is promoted by hydrogen bonding with cytidine. Journal of the American Chemical Society 20070801
Cyclopentenyl cytosine (CPEC): an overview of its in vitro and in vivo activity. Current cancer drug targets 20070801
Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS. Journal of pharmaceutical and biomedical analysis 20070727
Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy? British journal of cancer 20070716
Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma. Cancer research 20070715
On the prebiotic synthesis of ribonucleotides: photoanomerisation of cytosine nucleosides and nucleotides revisited. Chembiochem : a European journal of chemical biology 20070709
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine. Biochimica et biophysica acta 20070701
Importance of tRNA interactions with 23S rRNA for peptide bond formation on the ribosome: studies with substrate analogs. Biological chemistry 20070701
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer research 20070701
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. Immunity 20070701
Prediction of C-to-U RNA editing sites in higher plant mitochondria using only nucleotide sequence features. Biochemical and biophysical research communications 20070622
Stacking effects on local structure in RNA: changes in the structure of tandem GA pairs when flanking GC pairs are replaced by isoG-isoC pairs. The journal of physical chemistry. B 20070621
Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation? Journal of the neurological sciences 20070615
Surface-enhanced Raman spectroscopy of soft-landed polyatomic ions and molecules. Analytical chemistry 20070615
Possible involvement of supraspinal opioid and GABA receptors in CDP-choline-induced antinociception in acute pain models in rats. Neuroscience letters 20070613
Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells. Cancer letters 20070608
DNA deaminases AID and APOBEC3G act processively on single-stranded DNA. DNA repair 20070601
Cleavage of an RNA analog by Zn(II) macrocyclic catalysts appended with a methyl or an acridine group. Journal of inorganic biochemistry 20070601
Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil. Oncology reports 20070601
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice. Journal of immunology (Baltimore, Md. : 1950) 20070601
Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro. Journal of veterinary science 20070601
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. Environmental health perspectives 20070601
DNA methyltransferases as targets for cancer therapy. Drugs of today (Barcelona, Spain : 1998) 20070601
[Single-nucleotide polymorphisms of the cytidine deaminase gene in 53 children with acute leukemia]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20070601
A review of the role of capecitabine in the treatment of colorectal cancer. Therapeutics and clinical risk management 20070601
A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer. British journal of cancer 20070507
Electrochemical behaviors of native and thermally denatured fish DNA in the presence of cytosine derivatives and porphyrin by cyclic voltammetry using boron-doped diamond electrode. Bioelectrochemistry (Amsterdam, Netherlands) 20070501
Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479. Bioorganic & medicinal chemistry letters 20070501
Magnaporthe grisea infection triggers RNA variation and antisense transcript expression in rice. Plant physiology 20070501
Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells. Oncology reports 20070501
Treatment combining X-irradiation and a ribonucleoside anticancer drug, TAS106, effectively suppresses the growth of tumor cells transplanted in mice. International journal of radiation oncology, biology, physics 20070501
Centrosomal latency of incoming foamy viruses in resting cells. PLoS pathogens 20070501
Synthesis of 3'-deoxynucleosides with 2-oxabicyclo[3.1.0]hexane sugar moieties: addition of difluorocarbene to a 3',4'-unsaturated uridine derivative and 1,2-dihydrofurans derived from D- and L-xylose1. The Journal of organic chemistry 20070427
A nearly isosteric photosensitive amide-backbone substitution allows enzyme activity switching in ribonuclease s. Journal of the American Chemical Society 20070425
Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA. The Journal of biological chemistry 20070420
Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness. The Journal of biological chemistry 20070420
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. Journal of immunology (Baltimore, Md. : 1950) 20070415
Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions. Virology 20070410
Selective inhibition of Alu retrotransposition by APOBEC3G. Gene 20070401
Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias. Molecular immunology 20070401
Thermodynamic properties of enzyme-catalyzed reactions involving cytosine, uracil, thymine, and their nucleosides and nucleotides. Biophysical chemistry 20070401
Kinetic analysis of oligo(C) formation from the 5'-monophosphorimidazolide of cytidine with Pb(II) ion catalyst at 10-75 degrees C. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20070401
Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation. Journal of virology 20070401
Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells. Pharmacological research 20070401
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G: a possible role in the resistance to HIV of HIV-exposed seronegative individuals. The Journal of infectious diseases 20070401
Arsenic trioxide induces p53-dependent apoptotic signals in myeloma cells with SiRNA-silenced p53: MAP kinase pathway is preferentially activated in cells expressing inactivated p53. International journal of oncology 20070401
DNA-dependent protein kinase inhibits AID-induced antibody gene conversion. PLoS biology 20070401
Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3' activation-induced cytidine deaminase target. Journal of immunology (Baltimore, Md. : 1950) 20070401
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nature medicine 20070401
Progesterone regulation of implantation-related genes: new insights into the role of oestrogen. Cellular and molecular life sciences : CMLS 20070401
Providing AID to p53 mutagenesis. Nature medicine 20070401
Cell-specific regulation of APOBEC3F by interferons. Acta biochimica et biophysica Sinica 20070401
Population stratification of a common APOBEC gene deletion polymorphism. PLoS genetics 20070401
HyperPack: a software package for the study of levels, contexts, and patterns of APOBEC-mediated hypermutation in HIV. AIDS research and human retroviruses 20070401
Electron-transfer induced repair of 6-4 photoproducts in DNA: a computational study. The journal of physical chemistry. A 20070329
A novel human B cell subpopulation representing the initial germinal center population to express AID. Blood 20070315
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. Journal of immunology (Baltimore, Md. : 1950) 20070315
Recombination in feline lentiviral genomes during experimental cross-species infection. Virology 20070301
Analysis of Vif-induced APOBEC3G degradation using an alpha-complementation assay. Virology 20070301
2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus. Antiviral research 20070301
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Molecular pharmacology 20070301
Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF. Experimental gerontology 20070301
Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules. Journal of virology 20070301
Expression and secretion of immunoglobulin alpha heavy chain with diverse VDJ recombinations by human epithelial cancer cells. Molecular immunology 20070301
Functional characterization of APOBEC-1 complementation factor phosphorylation sites. Biochimica et biophysica acta 20070301
The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana. The Plant journal : for cell and molecular biology 20070301
Post-transcriptional modifications in the small subunit ribosomal RNA from Thermotoga maritima, including presence of a novel modified cytidine. RNA (New York, N.Y.) 20070301
APOBEC-mediated viral restriction: not simply editing? Trends in biochemical sciences 20070301
Specific targeted antiviral therapy for hepatitis C. Current gastroenterology reports 20070301
A possible role of thymidine phosphorylase expression and 5-fluorouracil increased sensitivity in oropharyngeal cancer patients. Journal of cellular and molecular medicine 20070301
HPLC retention behavior on hydride-based stationary phases. Journal of separation science 20070301
APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature 20070222
LC-MS/MS method for simultaneous determination of viramidine and ribavirin levels in monkey red blood cells. Journal of pharmaceutical and biomedical analysis 20070219
Synthesis of 2'-C-alpha-(hydroxyalkyl) and 2'-C-alpha-alkylcytidine phosphoramidites: analogues for probing solvent interactions with RNA. The Journal of organic chemistry 20070216
AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells. Journal of immunology (Baltimore, Md. : 1950) 20070215
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Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling. Biochemistry 20070213
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. The Journal of biological chemistry 20070209
The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action. DNA repair 20070204
Activation-induced cytidine deaminase acts on double-strand breaks in vitro. Molecular immunology 20070201
Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations. Molecular immunology 20070201
Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis. International journal of cancer 20070201
Genetic association of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86 bp repeat) polymorphisms with Type 2 diabetes mellitus in North Indians. Clinica chimica acta; international journal of clinical chemistry 20070201
Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells. Clinica chimica acta; international journal of clinical chemistry 20070201
Purine and pyrimidine nucleosides preserve human astrocytoma cell adenylate energy charge under ischemic conditions. Neurochemistry international 20070201
Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells. Journal of immunology (Baltimore, Md. : 1950) 20070201
Dual effect of APOBEC3G on Hepatitis B virus. The Journal of general virology 20070201
Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. Experimental hematology 20070201
Nitrogenous ovipositional deterrents in the leaves of sweet pepper (Capsicum annuum) at the mature stage against the leafminer, Liriomyza trifolii (Burgess). Bioscience, biotechnology, and biochemistry 20070201
Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. PLoS pathogens 20070201
[DNA methylation and cancer]. Gan to kagaku ryoho. Cancer & chemotherapy 20070201
Generation and characterization of APOBEC3G-positive 293T cells for HIV-1 Vif study. The journal of medical investigation : JMI 20070201
Cloning and characterization of an alternative splicing transcript of the gene coding for human cytidine deaminase. Biochemistry and cell biology = Biochimie et biologie cellulaire 20070201
APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G. The Journal of biological chemistry 20070126
The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature 20070125
Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T. The Journal of experimental medicine 20070122
Photophysical characterization of a cytidine-guanosine tethered phthalocyanine-fullerene dyad. Chemical communications (Cambridge, England) 20070121
Biochemical differentiation of APOBEC3F and APOBEC3G proteins associated with HIV-1 life cycle. The Journal of biological chemistry 20070119
Antibody class switching mediated by yeast endonuclease-generated DNA breaks. Science (New York, N.Y.) 20070119
Immunology. Antibodies get a break. Science (New York, N.Y.) 20070119
Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination. The Journal of biological chemistry 20070105
AID mutates a non-immunoglobulin transgene independent of chromosomal position. Molecular immunology 20070101
Somatic mutations and activation-induced cytidine deaminase (AID) expression in established rheumatoid factor-producing lymphoblastoid cell line. Molecular immunology 20070101
HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E. coli by a similar mechanism of action. Molecular immunology 20070101
Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients. Cancer chemotherapy and pharmacology 20070101
Regulation of epsilon germline transcription and switch region mutations by IgH locus 3' enhancers in transgenic mice. Blood 20070101
APOBEC3G expression is restricted to epithelial cells of the proximal convoluted tubules and is not expressed in the glomeruli of macaques. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070101
The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity. Extremophiles : life under extreme conditions 20070101
Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy. RNA (New York, N.Y.) 20070101
Human T cell leukemia virus type I is resistant to the antiviral effects of APOBEC3. Journal of virological methods 20070101
Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101
Collision-induced dissociation of cytidine and its derivatives. Journal of mass spectrometry : JMS 20070101
Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells. European journal of immunology 20070101
Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models. Scandinavian journal of gastroenterology 20070101
Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070101
Insights into DNA deaminases. Nature structural & molecular biology 20070101
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma. The Journal of allergy and clinical immunology 20070101
Expression of APOBEC3G in kidney cells. Tissue antigens 20070101
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells. Molecular cancer 20070101
Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB. BMC molecular biology 20070101
Construction and characterization of new piggyBac vectors for constitutive or inducible expression of heterologous gene pairs and the identification of a previously unrecognized activator sequence in piggyBac. BMC biotechnology 20070101
FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders. BMC cancer 20070101
Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals. PLoS genetics 20070101
Reconstitution of an infectious human endogenous retrovirus. PLoS pathogens 20070101
Effect of gonococcal lipooligosaccharide variation on human monocytic cytokine profile. BMC microbiology 20070101
New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu. Retrovirology 20070101
Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion. Mitochondrion 20070101
Molecular mechanisms of antibody somatic hypermutation. Annual review of biochemistry 20070101
Regulation of AID function in vivo. Advances in experimental medicine and biology 20070101
Targeting of AID to immunoglobulin genes. Advances in experimental medicine and biology 20070101
Targeting AID to the Ig genes. Advances in experimental medicine and biology 20070101
Regulation of activation induced deaminase via phosphorylation. Advances in experimental medicine and biology 20070101
Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation. Genome biology 20070101
Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs. Anticancer research 20070101
Regulation of metabolic networks by small molecule metabolites. BMC bioinformatics 20070101
Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response. Virology journal 20070101
APOBEC3G levels predict rates of progression to AIDS. Retrovirology 20070101
C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and -independent pathways. BMC developmental biology 20070101
Model structure of human APOBEC3G. PloS one 20070101
A recurrent stop-codon mutation in succinate dehydrogenase subunit B gene in normal peripheral blood and childhood T-cell acute leukemia. PloS one 20070101
Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in Moroccan population. Journal of biomedicine & biotechnology 20070101
Quantitative determination of the cytidine deaminase inhibitor tetrahydrouridine (THU) in mouse plasma by liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Detection of cancer clones in human colorectal adenoma as revealed by increased DNA instability and other bio-markers. European journal of histochemistry : EJH 20070101
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system. Virology journal 20070101
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Advances in immunology 20070101
DNA deamination in immunity: AID in the context of its APOBEC relatives. Advances in immunology 20070101
The role of activation-induced deaminase in antibody diversification and chromosome translocations. Advances in immunology 20070101
Targeting of AID-mediated sequence diversification by cis-acting determinants. Advances in immunology 20070101
AID-initiated purposeful mutations in immunoglobulin genes. Advances in immunology 20070101
Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Advances in immunology 20070101
Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection. Advances in immunology 20070101
Role of AID in tumorigenesis. Advances in immunology 20070101
Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies. Advances in immunology 20070101
Immunoglobulin somatic hypermutation. Annual review of genetics 20070101
DNA-uracil and human pathology. Molecular aspects of medicine 20070101
Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer. BMC cancer 20070101
Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus. Journal of diabetes and its complications 20070101
Biochemical characterization of a recombinant Japanese encephalitis virus RNA-dependent RNA polymerase. BMC molecular biology 20070101
Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions. Retrovirology 20070101
Nucleoside and nucleotide reverse transcriptase inhibitors in children. Clinical drug investigation 20070101
Mass spectrometric identification of Rab23 phosphorylation as a response to challenge by cytidine 3',5'-cyclic monophosphate in mouse brain. Rapid communications in mass spectrometry : RCM 20070101
Host factors influencing susceptibility to HIV infection and AIDS progression. Retrovirology 20070101
Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the Myxomycota. Methods in enzymology 20070101
Measuring editing activity and identifying cytidine-to-uridine mRNA editing factors in cells and biochemical isolates. Methods in enzymology 20070101
Mouse models as tools to explore cytidine-to-uridine RNA editing. Methods in enzymology 20070101
Characterization of the de novo biosynthetic enzyme of platelet activating factor, DDT-insensitive cholinephosphotransferase, of human mesangial cells. Mediators of inflammation 20070101
Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity. Retrovirology 20070101
The restriction of zoonotic PERV transmission by human APOBEC3G. PloS one 20070101
[Subcellular localization of APOBEC3G by confocal laser scanning microscope (CLSM)]. Bing du xue bao = Chinese journal of virology 20070101
Immunodeficiencies due to defects of class-switch recombination. Immunologic research 20070101
Intraperitoneal administration of CDP-choline and its cholinergic and pyrimidinergic metabolites induce hyperglycemia in rats: involvement of the sympathoadrenal system. Archives of physiology and biochemistry 20070101
DMS footprinting of structured RNAs and RNA-protein complexes. Nature protocols 20070101
The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. BMC structural biology 20070101
Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2. BMC molecular biology 20070101
Development of novel thioguanosine analogs with the ability to specifically modify cytidine. Nucleic acids symposium series (2004) 20070101
Synthesis of 4'-selenoribonucleosides. Nucleic acids symposium series (2004) 20070101
Enzymatic incorporation of 2-amino-6-vinylpurine derivative. Nucleic acids symposium series (2004) 20070101
A novel apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis--the possibility of RNase L activated pathway as a target of ECyd. Nucleic acids symposium series (2004) 20070101
Global DNA hypomethylation in liver cancer cases and controls: a phase I preclinical biomarker development study. Epigenetics 20070101
The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G. Retrovirology 20070101
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. BMC biochemistry 20070101
Studies on thermal stability of human cytidine deaminase. Nucleosides, nucleotides & nucleic acids 20070101
Synthesis of pyrene labeled RNA for fluorescence measurements. Nucleosides, nucleotides & nucleic acids 20070101
Homogeneous fluorescence assays for RNA diagnosis by pyrene-conjugated 2'-O-methyloligoribonucleotides. Nucleosides, nucleotides & nucleic acids 20070101
Choke point analysis of metabolic pathways in E.histolytica: a computational approach for drug target identification. Bioinformation 20070101
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Critical reviews in immunology 20070101
Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies. Bioinorganic chemistry and applications 20070101
Activation-induced cytidine deaminase expression in gastric cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20070101
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer. British journal of cancer 20061218
Nanostructures of APOBEC3G support a hierarchical assembly model of high molecular mass ribonucleoprotein particles from dimeric subunits. The Journal of biological chemistry 20061215
Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice. Clinical cancer research : an official journal of the American Association for Cancer Research 20061215
N-terminal and C-terminal cytosine deaminase domain of APOBEC3G inhibit hepatitis B virus replication. World journal of gastroenterology 20061214
Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth. Blood 20061201
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Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains. The Journal of biological chemistry 20061201
Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers. Journal of immunology (Baltimore, Md. : 1950) 20061201
Template properties of mutagenic cytosine analogues in reverse transcription. Nucleic acids research 20061201
Transcriptional regulation by competing transcription factor modules. PLoS computational biology 20061201
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mRNA expression and RNA editing (2451 C-to-U) of IL-12 receptor beta2 in adult atopic patients. Journal of Korean medical science 20061201
The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens. PLoS pathogens 20061201
Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography. Pharmeuropa scientific notes 20061201
Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes. Therapeutics and clinical risk management 20061201
Numerical characterization of DNA sequences based on the k-step Markov chain transition probability. Journal of computational chemistry 20061130
The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1. Biochemical and biophysical research communications 20061117
Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. Cancer research 20061115
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic. Biochemical and biophysical research communications 20061110
Addition of difluorocarbene to 4',5'-unsaturated nucleosides: synthesis and deoxygenation reactions of difluorospirocyclopropane nucleosides. The Journal of organic chemistry 20061110
Computational analyses show A-to-G mutations correlate with nascent mRNA hairpins at somatic hypermutation hotspots. DNA repair 20061108
Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107
Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho. The Journal of biological chemistry 20061103
Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine. Journal of medicinal chemistry 20061102
Additional food folate derived exclusively from natural sources improves folate status in young women with the MTHFR 677 CC or TT genotype. The Journal of nutritional biochemistry 20061101
Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model. Blood 20061101
HIV accomplices and adversaries in macrophage infection. Journal of leukocyte biology 20061101
Enthalpy of the B-to-Z conformational transition of a DNA oligonucleotide determined by isothermal titration calorimetry. Biophysical journal 20061101
High expression of APOBEC3G in patients infected with hepatitis C virus. Journal of molecular histology 20061101
Natural resistance to HIV infection: The Vif-APOBEC interaction. Comptes rendus biologies 20061101
A role for PCNA ubiquitination in immunoglobulin hypermutation. PLoS biology 20061101
Novel in vitro screening system for monoclonal antibodies using hypermutating chicken B cell library. Journal of bioscience and bioengineering 20061101
The antinociceptive effects of centrally administered CDP-choline on acute pain models in rats: the involvement of cholinergic system. Brain research 20061030
Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells. Journal of immunological methods 20061020
Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases. Journal of medicinal chemistry 20061019
Base and phosphate electron detachment energies of deoxyribonucleotide anions. Journal of the American Chemical Society 20061018
Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice. Journal of immunology (Baltimore, Md. : 1950) 20061015
Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells. European journal of pharmacology 20061010
APOBEC3G genetic variants and their association with risk of HIV infection in highly exposed Caucasians. AIDS (London, England) 20061003
Differential expression patterns of recombination-activating genes in individual mature B cells in juvenile idiopathic arthritis. Annals of the rheumatic diseases 20061001
Trypanosoma brucei: a survey of pyrimidine transport activities. Experimental parasitology 20061001
An accurate fluorescent assay for quantifying the extent of RNA editing. RNA (New York, N.Y.) 20061001
STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha. Journal of immunology (Baltimore, Md. : 1950) 20061001
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. Immunity 20061001
Boronate functionalised polymer monoliths for microscale affinity chromatography. The Analyst 20061001
A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice. Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
[Inhibition of hepatitis B and duck hepatitis B virus replication by APOBEC3G]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20061001
Interaction between HIV-1 and APOBEC3 sub-family of proteins. Current HIV research 20061001
DNA repair in HIV-1 infection: a case for inhibitors of cellular co-factors? Current HIV research 20061001
The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules. The Journal of biological chemistry 20060929
Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood 20060915
Flexibility and adaptability in binding of E. coli cytidine repressor to different operators suggests a role in differential gene regulation. Journal of molecular biology 20060915
AID and Igh switch region-Myc chromosomal translocations. DNA repair 20060908
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice. The Journal of experimental medicine 20060904
Human cytidine deaminase: a three-dimensional homology model of a tetrameric metallo-enzyme inferred from the crystal structure of a distantly related dimeric homologue. Journal of molecular graphics & modelling 20060901
Uridine and cytidine in the brain: their transport and utilization. Brain research reviews 20060901
Activation-induced cytidine deaminase (AID) is expressed in normal spermatogenesis but only infrequently in testicular germ cell tumours. The Journal of pathology 20060901
PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice. American journal of physiology. Gastrointestinal and liver physiology 20060901
Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator. Cancer biology & therapy 20060901
Activation-induced deaminase: light and dark sides. Trends in molecular medicine 20060901
Pathogenesis of AIDS lymphoma: role of oncogenic viruses and B cell activation-associated molecular lesions. Current opinion in oncology 20060901
Induction of IgE and allergic-type responses in fur mite-infested mice. European journal of immunology 20060901
Antiviral potency of APOBEC proteins does not correlate with cytidine deamination. Journal of virology 20060901
Pax5--a critical inhibitor of plasma cell fate. Scandinavian journal of immunology 20060901
Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family. Acta crystallographica. Section D, Biological crystallography 20060901
Association between farm exposure and atopy, according to the CD14 C-159T polymorphism. The Journal of allergy and clinical immunology 20060901
Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacological reviews 20060901
Reactivation of p53 function with a demethylating agent. Cancer biology & therapy 20060901
Citicoline: pharmacological and clinical review, 2006 update. Methods and findings in experimental and clinical pharmacology 20060901
Citicoline (Cognizin) in the treatment of cognitive impairment. Clinical interventions in aging 20060901
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2. Biochemical and biophysical research communications 20060825
Syntheses, pi-stacking interactions and base-pairings of uracil pyridinium salts and uracilyl betaines with nucleobases. Organic & biomolecular chemistry 20060821
Comparison of ribonucleic acid homopolymer ionization energies and charge injection barriers. The journal of physical chemistry. B 20060817
Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms. Current biology : CB 20060808
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients. British journal of cancer 20060807
APOBEC3 proteins inhibit human LINE-1 retrotransposition. The Journal of biological chemistry 20060804
Reply to correspondence by Abreu-Silva et al. regarding Ballana et al.: Mutation T1291C in the mitochondrial 12S rRNA gene involved in deafness in a Cuban family belongs to the macrohaplogroup L1 of African origin. Biochemical and biophysical research communications 20060804
Solventless protocol for efficient bis-N-boc protection of adenosine, cytidine, and guanosine derivatives. The Journal of organic chemistry 20060804
Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs. Journal of the American Chemical Society 20060802
Mutational dynamics in human tumors confirm the neutral intrinsic instability of the mitochondrial D-loop poly-cytidine repeat. Genes, chromosomes & cancer 20060801
In vitro selected Con1 subgenomic replicons resistant to 2'-C-methyl-cytidine or to R1479 show lack of cross resistance. Virology 20060801
Tissue-specific sensitivity to AID expression in transgenic mouse models. Gene 20060801
Targeting of somatic hypermutation. Nature reviews. Immunology 20060801
Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate. Acta crystallographica. Section F, Structural biology and crystallization communications 20060801
Interleukin-5 regulates genes involved in B-cell terminal maturation. Immunology 20060801
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 20060801
[HIV-1 and ubiquitination]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20060801
[AID controls immunoglobulin class switch recombination]. Seikagaku. The Journal of Japanese Biochemical Society 20060801
Inhibition of hepatitis B virus replication by APOBEC3G in vitro and in vivo. World journal of gastroenterology 20060728
Application of a solid-phase beta-triphosphitylating reagent in the synthesis of nucleoside beta-triphosphates. The Journal of organic chemistry 20060721
Vif-deficient HIV reverse transcription complexes (RTCs) are subject to structural changes and mutation of RTC-associated reverse transcription products. Virology 20060720
Identification of a specific domain required for dimerization of activation-induced cytidine deaminase. The Journal of biological chemistry 20060714
Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile. Journal of molecular modeling 20060701
A phase I clinical and pharmacokinetic study of CS-682 administered orally in advanced malignant solid tumors. Investigational new drugs 20060701
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine. Molecular pharmacology 20060701
Association of a polymorphism in the betacellulin gene with type 1 diabetes mellitus in two populations. Journal of molecular medicine (Berlin, Germany) 20060701
Gene conversion in human rearranged immunoglobulin genes. Immunogenetics 20060701
The role of the interleukin-10 subfamily members in immunoglobulin production by human B cells. Scandinavian journal of immunology 20060701
Structural phylogenetic analysis of activation-induced deaminase function. Journal of immunology (Baltimore, Md. : 1950) 20060701
E2A expression stimulates Ig hypermutation. Journal of immunology (Baltimore, Md. : 1950) 20060701
Mass spectrometric identification and characterization of antimony complexes with ribose-containing biomolecules and an RNA oligomer. Analytical and bioanalytical chemistry 20060701
Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: Potential involvement of proteins from hemocytes revealed by a proteomic approach. Acta tropica 20060701
Antigen receptors and somatic hypermutation in B-cell chronic lymphocytic leukemia with Richter's transformation. Haematologica 20060701
p53 expression after treatment with zebularine is not due to demethylation. Cancer research 20060701
Reversal of HIV drug resistance and novel strategies to curb HIV infection: the viral infectivity factor Vif as a target and tool of therapy. Current drug targets 20060701
Dissecting non-canonical interactions in frameshift-stimulating mRNA pseudoknots. Journal of biomolecular NMR 20060701
The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse. Biochemistry 20060627
First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies. The Journal of biological chemistry 20060623
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism. The Journal of biological chemistry 20060623
Phase I/II trial of doxorubicin and fixed dose-rate infusion gemcitabine in advanced soft tissue sarcomas: a GEIS study. British journal of cancer 20060619
Primary cutaneous follicle center lymphoma and primary cutaneous large B-cell lymphoma, leg type, are both targeted by aberrant somatic hypermutation but demonstrate differential expression of AID. Blood 20060615
A role for Mlh3 in somatic hypermutation. DNA repair 20060610
Assembly of HIV-1 Vif-Cul5 E3 ubiquitin ligase through a novel zinc-binding domain-stabilized hydrophobic interface in Vif. Virology 20060605
Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control. British journal of cancer 20060605
Long intracellular retention of 4'-thio-arabinofuranosylcytosine 5'-triphosphate as a critical factor for the anti-solid tumor activity of 4'-thio-arabinofuranosylcytosine. Cancer chemotherapy and pharmacology 20060601
Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation. Leukemia 20060601
Reaction of cytidine nucleotides with cyanoacetylene: support for the intermediacy of nucleoside-2',3'-cyclic phosphates in the prebiotic synthesis of RNA. Chembiochem : a European journal of chemical biology 20060601
Characterization of BlsM, a nucleotide hydrolase involved in cytosine production for the biosynthesis of blasticidin S. Chembiochem : a European journal of chemical biology 20060601
Multifaceted antiviral actions of APOBEC3 cytidine deaminases. Trends in immunology 20060601
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication. Hepatology (Baltimore, Md.) 20060601
Class switch recombination in selective IgA-deficient subjects. Clinical and experimental immunology 20060601
AID for innate immunity to retroviral transformation. Immunity 20060601
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. Immunity 20060601
APOBEC3G expression is restricted to neurons in the brains of pigtailed macaques. AIDS research and human retroviruses 20060601
Improved circadian sleep-wake cycle in infants fed a day/night dissociated formula milk. Neuro endocrinology letters 20060601
[Host factors that regulate the intercellular dynamics of HIV-1 genome during the early phase of infection]. Uirusu 20060601
Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates. Virology 20060525
Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase. Biochemistry 20060523
A fibrinogen deficiency accelerates the initiation of LDL cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice. Blood 20060515
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells. Blood 20060515
Unstructured RNA is a substrate for tRNase Z. Biochemistry 20060502
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA (New York, N.Y.) 20060501
High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA. Nature structural & molecular biology 20060501
Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1. Molecular microbiology 20060501
APOBEC deaminases as cellular antiviral factors: a novel natural host defense mechanism. Medical science monitor : international medical journal of experimental and clinical research 20060501
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies. PLoS pathogens 20060501
Dancin' deaminase. Nature structural & molecular biology 20060501
Cellular pharmacology of gemcitabine. Annals of oncology : official journal of the European Society for Medical Oncology 20060501
Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC. Journal of separation science 20060501
Review: recent clinical trials in epigenetic therapy. Reviews on recent clinical trials 20060501
Innate cellular defenses of APOBEC3 cytidine deaminases and viral counter-defenses. Current opinion in HIV and AIDS 20060501
Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy. Cancer letters 20060428
[Search for mitochondrial DNA T4291C mutation in Hungarian patients with metabolic syndrome]. Orvosi hetilap 20060416
Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines. Cancer research 20060415
Electrodeposited sol-gel-imprinted sensing film for cytidine recognition on Au-electrode surface. Talanta 20060415
Synthesis of 3'-beta-carbamoylmethylcytidine (CAMC) and its derivatives as potential antitumor agents. Organic & biomolecular chemistry 20060407
The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40. Molecular immunology 20060401
Episomal vectors to monitor and induce somatic hypermutation in human Burkitt-Lymphoma cell lines. Molecular immunology 20060401
Impaired class switch recombination (CSR) in Waldenstrom macroglobulinemia (WM) despite apparently normal CSR machinery. Blood 20060401
Authors reply to I.B. Rogozin and Y.I. Pavlov: 'The cytidine deaminase AID exhibits similar functional properties in yeast and mammals'. Molecular immunology 20060401
Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Molecular immunology 20060401
Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints. Journal of magnetic resonance (San Diego, Calif. : 1997) 20060401
Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter. Human genetics 20060401
Decoupling of normal CD40/interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell lines. Leukemia 20060401
AID in somatic hypermutation and class switch recombination. Current opinion in immunology 20060401
Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes. Microbiology (Reading, England) 20060401
Diversified bursal medullary B cells survive and expand independently after depletion following neonatal infectious bursal disease virus infection. Immunology 20060401
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer research 20060401
Intracellular restriction factors in mammalian cells--An ancient defense system finds a modern foe. Current HIV research 20060401
Defects of class-switch recombination. The Journal of allergy and clinical immunology 20060401
Formulation, quality control and shelf life of the experimental cytostatic drug cyclopentenyl cytosine. Drug development and industrial pharmacy 20060401
HIV pathogenesis: knowledge gained after two decades of research. Advances in dental research 20060401
An overview of cytidine deaminases. International journal of hematology 20060401
The dark side of activation-induced cytidine deaminase: relationship with leukemia and beyond. International journal of hematology 20060401
Lentiviral Vif: viral hijacker of the ubiquitin-proteasome system. International journal of hematology 20060401
APOBEC family proteins: novel antiviral innate immunity. International journal of hematology 20060401
APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. The Journal of biological chemistry 20060331
Directed DNA deamination by AID/APOBEC3 in immunity. Current biology : CB 20060321
Crystal structure of a bifunctional deaminase and reductase from Bacillus subtilis involved in riboflavin biosynthesis. The Journal of biological chemistry 20060317
AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies. Blood 20060315
Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics. Clinical cancer research : an official journal of the American Association for Cancer Research 20060315
Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes. Biochemical and biophysical research communications 20060310
Synthesis and anti-HIV activity of D- and L-thietanose nucleosides. Journal of medicinal chemistry 20060309
APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Current biology : CB 20060307
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature 20060302
MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells. Molecular immunology 20060301
The cytidine deaminase AID exhibits similar functional properties in yeast and mammals. Molecular immunology 20060301
Pyrrolo-C as a fluorescent probe for monitoring RNA secondary structure formation. RNA (New York, N.Y.) 20060301
Validation of real-time reverse-transcription-polymerase chain reaction for quantification of capecitabine-metabolizing enzymes. Analytical biochemistry 20060301
Seasonal changes of nucleotides in mussel (Mytilus galloprovincialis) mantle tissue. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060301
Feline lentivirus evolution in cross-species infection reveals extensive G-to-A mutation and selection on key residues in the viral polymerase. Journal of virology 20060301
Facial nerve paralysis after impacted lower third molar surgery: a literature review and case report. Medicina oral, patologia oral y cirugia bucal 20060301
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer research 20060301
Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. British journal of cancer 20060227
Cytidine 5'-monophosphate (CMP)-induced structural changes in a multifunctional sialyltransferase from Pasteurella multocida. Biochemistry 20060221
The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture. The Journal of biological chemistry 20060217
3'-N-Alkylamino-3'-deoxy-ara-uridines: a new class of potential inhibitors of ribonuclease A and angiogenin. Bioorganic & medicinal chemistry 20060215
Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide. Biochemistry 20060214
Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions. Journal of the American Chemical Society 20060208
Expression of APOBEC2 is transcriptionally regulated by NF-kappaB in human hepatocytes. FEBS letters 20060206
Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202
The cytidine deaminases AID and APOBEC-1 exhibit distinct functional properties in a novel yeast selectable system. Molecular immunology 20060201
Simultaneous expression of apolipoprotein B mRNA editing enzyme and scavenger receptor BI mediated by a therapeutic gene expression system. Atherosclerosis 20060201
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene. Molecular immunology 20060201
The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma. Blood 20060201
Angiostatic activity of DNA methyltransferase inhibitors. Molecular cancer therapeutics 20060201
Cellular restriction factors affecting the early stages of HIV replication. Current HIV/AIDS reports 20060201
The correlation of RNase A enzymatic activity with the changes in the distance between Nepsilon2-His12 and N delta1-His119 upon addition of stabilizing and destabilizing salts. The protein journal 20060201
Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. British journal of cancer 20060130
AID-dependent histone acetylation is detected in immunoglobulin S regions. The Journal of experimental medicine 20060123
Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex. Virology 20060120
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Molecular cell 20060120
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The first radical method for the introduction of an ethynyl group using a silicon tether and its application to the synthesis of 2'-deoxy-2'-C-ethynylnucleosides. The Journal of organic chemistry 20030502
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Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine. Bioorganic & medicinal chemistry letters 20030310
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Cellular pharmacology of D-d4FC, a nucleoside analogue active against drug-resistant HIV. Antiviral chemistry & chemotherapy 20030101
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