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Home > Other Heterocycles > 64744-50-9
64744-50-9 | 2-Azaspiro[4.5]decan-3-one
CAS No: 64744-50-9 Catalog No: AG003KGU MDL No:MFCD00177938
Product Description
Catalog Number:
AG003KGU
Chemical Name:
2-Azaspiro[4.5]decan-3-one
CAS Number:
64744-50-9
Molecular Formula:
C9H15NO
Molecular Weight:
153.2215
MDL Number:
MFCD00177938
IUPAC Name:
2-azaspiro[4.5]decan-3-one
InChI:
InChI=1S/C9H15NO/c11-8-6-9(7-10-8)4-2-1-3-5-9/h1-7H2,(H,10,11)
InChI Key:
JAWPQJDOQPSNIQ-UHFFFAOYSA-N
SMILES:
O=C1NCC2(C1)CCCCC2
UNII:
0IP6953295
Properties
Complexity:
170
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
153.115g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
153.225g/mol
Monoisotopic Mass:
153.115g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.5
Literature
| Title | Journal |
|---|---|
| The stabilizing effect of moisture on the solid-state degradation of gabapentin. | AAPS PharmSciTech 20110901 |
| Novel neuroprotective strategies in ischemic retinal lesions. | International journal of molecular sciences 20100101 |
| Gabapentin-lactum-chloranilic acid (1/1). | Acta crystallographica. Section E, Structure reports online 20100101 |
| Development and application of a validated HPLC method for the analysis of dissolution samples of gabapentin drug products. | Journal of pharmaceutical and biomedical analysis 20080107 |
| Development and application of a validated HPLC method for the determination of gabapentin and its major degradation impurity in drug products. | Journal of pharmaceutical and biomedical analysis 20070411 |
| Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations. | International journal of pharmaceutics 20070306 |
| Gabapentin-lactam induces dendritic filopodia and motility in cultured hippocampal neurons. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease. | Naunyn-Schmiedeberg's archives of pharmacology 20040801 |
| Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: evidence for involvement of mitochondrial KATP channels. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20040301 |
| Determination of gabapentin-lactam in serum of patients under gabapentin therapy. | Arzneimittel-Forschung 20040101 |
| The neuroprotective properties of gabapentin-lactam. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20011101 |
| [The effect of gabapentin and gabapentin-lactam on retinal ganglion cell survival. Situation after acute retinal ischemia in animal models]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010301 |
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