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64-85-7

64-85-7 | 11-DeoXycorticosterone

CAS No: 64-85-7 Catalog No: AG003DUV MDL No:MFCD00003661

Product Description

Catalog Number:
AG003DUV
Chemical Name:
11-DeoXycorticosterone
CAS Number:
64-85-7
Molecular Formula:
C21H30O3
Molecular Weight:
330.4611
MDL Number:
MFCD00003661
IUPAC Name:
(8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
InChI:
InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1
InChI Key:
ZESRJSPZRDMNHY-YFWFAHHUSA-N
SMILES:
OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C
EC Number:
200-596-4
UNII:
40GP35YQ49

Properties

Complexity:
606  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
330.219g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
330.468g/mol
Monoisotopic Mass:
330.219g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
54.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9  

Literature

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Infusions of bicuculline to the ventral tegmental area attenuates sexual, exploratory, and anti-anxiety behavior of proestrous rats. Pharmacology, biochemistry, and behavior 20091001
Immunosuppression improves blood pressure and endothelial function in a rat model of pregnancy-induced hypertension. American journal of hypertension 20091001
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. Journal of cellular biochemistry 20091001
Reduction of kidney damage by supplementation of vitamins C and E in rats with deoxycorticosterone-salt-induced hypertension. Iranian journal of kidney diseases 20091001
Structural and functional characterization of the interdomain interaction in the mineralocorticoid receptor. Molecular endocrinology (Baltimore, Md.) 20090901
Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension. American journal of physiology. Renal physiology 20090901
Are macrophages the foot soldiers in the war waged by aldosterone against the heart? Hypertension (Dallas, Tex. : 1979) 20090901
Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension (Dallas, Tex. : 1979) 20090901
Changes in serum and renal vitamin E levels in deoxycorticosterone acetate-salt hypertensive rats. Transplantation proceedings 20090901
Growth arrest specific protein 6 participates in DOCA-induced target-organ damage. Hypertension (Dallas, Tex. : 1979) 20090801
Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension. Clinical and experimental pharmacology & physiology 20090701
Heme arginate suppresses cardiac lesions and hypertrophy in deoxycorticosterone acetate-salt hypertension. Experimental biology and medicine (Maywood, N.J.) 20090701
Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions. Journal of neurochemistry 20090701
Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice. Journal of pharmacological sciences 20090501
Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors. The Journal of biological chemistry 20090320
Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function. Clinical endocrinology 20090301
Excretion of norsteroids' phase II metabolites of different origin in human. Steroids 20090301
Hemin therapy attenuates kidney injury in deoxycorticosterone acetate-salt hypertensive rats. American journal of physiology. Renal physiology 20090301
Effect of Asparagus racemosus extract on transdermal delivery of carvedilol: a mechanistic study. AAPS PharmSciTech 20090301
Models of cardiovascular disease: measurement of antihypertensive activity in the conscious rat (SHR, DOCA-salt, and Goldblatt hypertension models). Current protocols in pharmacology 20090301
Close examination of steroidogenesis disorders in a DOC- and progesterone-producing adrenocortical carcinoma. Endocrine 20090201
Renin dynamics in adipose tissue: adipose tissue control of local renin concentrations. American journal of physiology. Endocrinology and metabolism 20090201
Timely drug delivery from controlled-release devices: dynamic analysis and novel design concepts. Mathematical biosciences 20090201
Impaired vasodilator activity in deoxycorticosterone acetate-salt hypertension is associated with increased protein O-GlcNAcylation. Hypertension (Dallas, Tex. : 1979) 20090201
Lack of nidogen-2 increases blood pressure, glomerular and tubulointerstitial damage in DOCA-salt hypertension. European journal of clinical investigation 20090201
Statin treatment reduces glomerular inflammation and podocyte damage in rat deoxycorticosterone-acetate-salt hypertension. Journal of hypertension 20090201
Conserved site for neurosteroid modulation of GABA A receptors. Neuropharmacology 20090101
Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells. Neuropharmacology 20090101
Proteinuria in mice expressing PKB/SGK-resistant GSK3. American journal of physiology. Renal physiology 20090101
Deletion of the alpha8 integrin gene does not protect mice from myocardial fibrosis in DOCA hypertension. American journal of hypertension 20090101
Distinct functions of vascular endothelial and smooth muscle PPARgamma in regulation of blood pressure and vascular tone. Toxicologic pathology 20090101
Deletion of the alpha-8 integrin gene does not protect mice from myocardial fibrosis in DOCA hypertension. American journal of hypertension 20090101
Antihypertensive effect of French maritime pine bark extract (Flavangenol): possible involvement of endothelial nitric oxide-dependent vasorelaxation. Journal of hypertension 20090101
Global upregulation of gene expression associated with renal dysfunction in DOCA-salt-induced hypertensive rats occurs via signaling cascades involving epidermal growth factor receptor: a microarray analysis. Vascular pharmacology 20090101
Depot-specific steroidogenic gene transcription in human adipose tissue. Clinical endocrinology 20081201
Estrogen is necessary for 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) infusion to the ventral tegmental area to facilitate social and sexual, but neither exploratory nor affective behavior of ovariectomized rats. Pharmacology, biochemistry, and behavior 20081201
Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension. The journal of sexual medicine 20081201
Intermedin ameliorates vascular and renal injury by inhibition of oxidative stress. American journal of physiology. Renal physiology 20081201
Sodium-, potassium-, chloride-, and bicarbonate-related effects on blood pressure and electrolyte homeostasis in deoxycorticosterone acetate-treated rats. American journal of physiology. Renal physiology 20081201
Functional state of adrenocortical system in rats with manifest alloxan-induced diabetes mellitus. Bulletin of experimental biology and medicine 20081201
Exploratory, anti-anxiety, social, and sexual behaviors of rats in behavioral estrus is attenuated with inhibition of 3alpha,5alpha-THP formation in the midbrain ventral tegmental area. Behavioural brain research 20081121
Tonic GABAergic inhibition of sympathetic preganglionic neurons: a novel substrate for sympathetic control. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101
Interaction among heme oxygenase, nuclear factor-kappaB, and transcription activating factors in cardiac hypertrophy in hypertension. Hypertension (Dallas, Tex. : 1979) 20081101
Aldosterone: from biosynthesis to non-genomic action onto the proteome. Steroids 20081001
Colfibrate attenuates blood pressure and sodium retention in DOCA-salt hypertension. Kidney international 20081001
In the ventral tegmental area, progestogens' membrane-mediated actions for lordosis of rats involve the second-messenger phospholipase C. Brain research 20080916
Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy. Journal of neurochemistry 20080901
Cardiac metabolic compensation to hypertension requires lipoprotein lipase. American journal of physiology. Endocrinology and metabolism 20080901
Transdermal delivery of carvedilol containing glycyrrhizin and chitosan as permeation enhancers: biochemical, biophysical, microscopic and pharmacodynamic evaluation. Drug delivery 20080901
Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism. Biological & pharmaceutical bulletin 20080901
GABAA receptor-mediated tonic currents in substantia gelatinosa neurons of rat spinal trigeminal nucleus pars caudalis. Neuroscience letters 20080829
Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080801
Glucocorticoid receptor phosphorylation differentially affects target gene expression. Molecular endocrinology (Baltimore, Md.) 20080801
Corticosteroid receptors involved in stress regulation in common carp, Cyprinus carpio. The Journal of endocrinology 20080801
Transient receptor potential vanilloid type 1 receptors in hypertensive renal damage: a promising therapeutic target? Hypertension (Dallas, Tex. : 1979) 20080801
Impaired purinergic neurotransmission to mesenteric arteries in deoxycorticosterone acetate-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20080801
Deletion of transient receptor potential vanilloid type 1 receptors exaggerates renal damage in deoxycorticosterone acetate-salt hypertension. Hypertension (Dallas, Tex. : 1979) 20080801
Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse. European journal of pharmacology 20080728
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy. Epilepsia 20080701
Cell type-specific GABA A receptor-mediated tonic inhibition in mouse neocortex. Journal of neurophysiology 20080701
Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20080701
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a. Hypertension (Dallas, Tex. : 1979) 20080701
Trace analysis of androgens and progestogens in environmental waters by ultra-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. A 20080627
5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. The Journal of pharmacology and experimental therapeutics 20080601
DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosum. Canadian journal of physiology and pharmacology 20080601
Are we missing a mineralocorticoid in teleost fish? Effects of cortisol, deoxycorticosterone and aldosterone on osmoregulation, gill Na+,K+ -ATPase activity and isoform mRNA levels in Atlantic salmon. General and comparative endocrinology 20080515
Plasma concentrations of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-1 and osteopontin reflect severity of heart failure in DOCA-salt hypertensive rat. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080501
Real-time analysis of gene regulation by glucocorticoid hormones. The Journal of endocrinology 20080501
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues. Journal of medicinal chemistry 20080410
Protective effects of estradiol in the brain of rats with genetic or mineralocorticoid-induced hypertension. Psychoneuroendocrinology 20080401
Aldosterone synthase deficiency caused by a homozygous L451F mutation in the CYP11B2 gene. Molecular genetics and metabolism 20080401
Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism. Hypertension (Dallas, Tex. : 1979) 20080401
Quantitative determination of progesterones and corticosteroids in human urine using gas chromatography/mass spectrometry: application to pelvic organ prolapse patients. Rapid communications in mass spectrometry : RCM 20080401
Dietary sesamin suppresses aortic NADPH oxidase in DOCA salt hypertensive rats. Clinical and experimental pharmacology & physiology 20080301
Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II. Kidney international 20080301
alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids. British journal of pharmacology 20080301
Spironolactone suppresses peritubular capillary loss and prevents deoxycorticosterone acetate/salt-induced tubulointerstitial fibrosis. Hypertension (Dallas, Tex. : 1979) 20080301
Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension. Circulation 20080226
Infusions of 3alpha,5alpha-THP to the VTA enhance exploratory, anti-anxiety, social, and sexual behavior and increase levels of 3alpha,5alpha-THP in midbrain, hippocampus, diencephalon, and cortex of female rats. Behavioural brain research 20080211
Mineralocorticoid signaling in transition to heart failure with normal ejection fraction. Hypertension (Dallas, Tex. : 1979) 20080201
Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects. Psychoneuroendocrinology 20080201
Angiotensin II: one driving force behind atherogenesis. Hypertension (Dallas, Tex. : 1979) 20080201
Deoxycorticosterone acetate salt hypertension in apolipoprotein E-/- mice results in accelerated atherosclerosis: the role of angiotensin II. Hypertension (Dallas, Tex. : 1979) 20080201
Purification and functional characterization of human 11beta hydroxylase expressed in Escherichia coli. The FEBS journal 20080201
Effects of ACTH, dexamethasone, and adrenalectomy on 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the rat central nervous system. The Journal of endocrinology 20080201
Novel mutation in cytochrome P450c17 causes complete combined 17alpha-hydroxylase/17,20-lyase deficiency. Journal of pediatric endocrinology & metabolism : JPEM 20080201
One single dose of etomidate negatively influences adrenocortical performance for at least 24h in children with meningococcal sepsis. Intensive care medicine 20080101
Effects of resibufogenin in experimental hypertension. American journal of nephrology 20080101
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. American journal of physiology. Regulatory, integrative and comparative physiology 20080101
The transcription of steroidogenic genes in the human cerebellum and hippocampus: a comparative survey of normal and Alzheimer's tissue. The Journal of endocrinology 20080101
Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout Oncorhynchus mykiss spermiation: implication with 17alpha, 20beta-dihydroxyprogesterone on the milt fluidity? Reproductive biology and endocrinology : RB&E 20080101
Patients with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency can achieve their target height: the Leipzig experience. Hormone research 20080101
An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution. BMC evolutionary biology 20080101
DOCA and TGF-beta induce early growth response gene-1 (Egr-1) expression. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Differential recruitment of tetratricorpeptide repeat domain immunophilins to the mineralocorticoid receptor influences both heat-shock protein 90-dependent retrotransport and hormone-dependent transcriptional activity. Biochemistry 20071211
The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy. Metabolic brain disease 20071201
Axl mediates vascular remodeling induced by deoxycorticosterone acetate-salt hypertension. Hypertension (Dallas, Tex. : 1979) 20071201
Influence of epipregnanolone on the modulation of rapid tolerance to ethanol by neurosteroids. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20071201
Maternal RAS influence on the ontogeny of thirst. Physiology & behavior 20071123
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function. American journal of physiology. Heart and circulatory physiology 20071001
Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration? Endocrinology 20071001
The role of polyester interstitium and aldosterone during structural development of renal tubules in serum-free medium. Biomaterials 20071001
Differential regulation of NADPH oxidase in sympathetic and sensory Ganglia in deoxycorticosterone acetate salt hypertension. Hypertension (Dallas, Tex. : 1979) 20071001
Pharmacological evidence of calcium-channel blockade by essential oil of Ocimum gratissimum and its main constituent, eugenol, in isolated aortic rings from DOCA-salt hypertensive rats. Fundamental & clinical pharmacology 20071001
GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. The Journal of physiology 20070915
DOCA stimulates salt appetite in Zucker rats: effect of dose, synergistic action with central angiotensin II, and obesity. Brain research bulletin 20070914
Glucocorticoids increase salt appetite by promoting water and sodium excretion. American journal of physiology. Regulatory, integrative and comparative physiology 20070901
Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin. American journal of physiology. Renal physiology 20070901
Mineralocorticoid escape by the kidney but not the heart in experimental asymptomatic left ventricular dysfunction. Hypertension (Dallas, Tex. : 1979) 20070901
PKC activation sets an upper limit to the functional plasticity of GABAergic transmission induced by endogenous neurosteroids. The European journal of neuroscience 20070901
Molecular evolution. Resurrected proteins reveal their surprising history. Science (New York, N.Y.) 20070817
Molecular basis for the GABAA receptor-mediated tonic inhibition in rat somatosensory cortex. Cerebral cortex (New York, N.Y. : 1991) 20070801
Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia. Hormones and behavior 20070801
Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase. Free radical biology & medicine 20070801
Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics. Journal of computer-aided molecular design 20070801
[11beta-hydroxylase deficiency: improvement of final height with growth hormone and gonadotropin-releasing hormone analog]. Anales de pediatria (Barcelona, Spain : 2003) 20070801
Fasudil attenuates myocardial fibrosis in association with inhibition of monocyte/macrophage infiltration in the heart of DOCA/salt hypertensive rats. Journal of cardiovascular pharmacology 20070801
Altered localization of GABA(A) receptor subunits on dentate granule cell dendrites influences tonic and phasic inhibition in a mouse model of epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070711
Increased sympathetic venoconstriction and reactivity to norepinephrine in mesenteric veins in anesthetized DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20070701
An analysis of the DOCA-salt model of hypertension in HO-1-/- mice and the Gunn rat. American journal of physiology. Heart and circulatory physiology 20070701
[Sepsis-like disease in an immunocompromised patient with a travel history to Mallorca]. Der Internist 20070701
Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei. The European journal of neuroscience 20070701
Salivary cortisol and DHEA levels in the Korean population: age-related differences, diurnal rhythm, and correlations with serum levels. Yonsei medical journal 20070630
Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities. The Journal of physiology 20070615
Serotonin-induced ion channel modulations in mesenteric artery myocytes from normotensive and DOCA-salt hypertensive rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20070601
Anticonvulsant actions of deoxycorticosterone. Brain research 20070511
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20070501
The 5-hydroxytryptamine2A receptor is involved in (+)-norfenfluramine-induced arterial contraction and blood pressure increase in deoxycorticosterone acetate-salt hypertension. The Journal of pharmacology and experimental therapeutics 20070501
Differential contributions of alpha-1 and alpha-2 adrenoceptors to vasoconstriction in mesenteric arteries and veins of normal and hypertensive mice. Vascular pharmacology 20070501
Synthesis and structure-activity relationships of a series of increasingly hydrophobic cationic steroid lipofection reagents. The journal of gene medicine 20070501
Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats. Naunyn-Schmiedeberg's archives of pharmacology 20070501
[Umbilicated blisters on sun-exposed skin]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20070401
Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice. American journal of physiology. Heart and circulatory physiology 20070401
Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats. The Journal of pharmacology and experimental therapeutics 20070401
Involvement of the endothelin ET(B) receptor in gender differences in deoxycorticosterone acetate-salt-induced hypertension. Clinical and experimental pharmacology & physiology 20070401
Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats. Journal of hypertension 20070401
The neurosteroid THDOC differentially affects spatial behavior and anesthesia in Slow and Fast kindling rat strains. Behavioural brain research 20070328
Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone. Endocrinology 20070301
The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7. Drug metabolism and disposition: the biological fate of chemicals 20070301
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle. Naunyn-Schmiedeberg's archives of pharmacology 20070301
Neurosteroid synthesis-mediated regulation of GABA(A) receptors: relevance to the ovarian cycle and stress. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070227
TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct. American journal of physiology. Renal physiology 20070201
Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker. American journal of physiology. Regulatory, integrative and comparative physiology 20070201
Mineralocorticoid pretreatment enhances angiotensin II-induced neuronal excitation but not salt drinking in male Fischer rats. Journal of neuroendocrinology 20070201
Severe loss-of-function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt-losing adrenal hypoplasia. Clinical endocrinology 20070201
DOCA/NaCl-induced chronic kidney disease: a comparison of renal nitric oxide production in resistant and susceptible rat strains. American journal of physiology. Renal physiology 20070101
Inhibition of NaCl appetite when DOCA-treated rats drink saline. American journal of physiology. Regulatory, integrative and comparative physiology 20070101
Biomechanical response of arterial wall to DOCA-salt hypertension in growing and middle-aged rats. Journal of biomechanics 20070101
Attenuated cardioprotective response to bradykinin, but not classical ischaemic preconditioning, in DOCA-salt hypertensive left ventricular hypertrophy. Pharmacological research 20070101
Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase. Cell biochemistry and biophysics 20070101
Evolution of the corticosteroid receptor signalling pathway in fish. General and comparative endocrinology 20070101
Concomitant secretion of glucocorticoid, androgens, and mineralocorticoid by an adrenocortical carcinoma: case report and review of literature. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101
Role of gp91phox-containing NADPH oxidase in the deoxycorticosterone acetate-salt-induced hypertension. European journal of pharmacology 20061215
Renal atrial natriuretic peptide receptors binding properties and function are resistant to DOCA-salt-induced hypertension in rats. Regulatory peptides 20061210
Time course of synergistic interaction between DOCA and salt on blood pressure: roles of vasopressin and hepatic osmoreceptors. American journal of physiology. Regulatory, integrative and comparative physiology 20061201
The role of the glucocorticoid receptor in mineralocorticoid/salt-mediated cardiac fibrosis. Endocrinology 20061201
Activation of potassium channels by tempol in arterial smooth muscle cells from normotensive and deoxycorticosterone acetate-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20061201
Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene. Clinical endocrinology 20061201
Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 20061123
Down-regulation of adrenal neuronal nitric oxide synthase mRNAs and proteins after deoxycorticosterone acetate-salt treatment in rats. The Journal of steroid biochemistry and molecular biology 20061101
Inhibition by alpha-tetrahydrodeoxycorticosterone (THDOC) of pre-sympathetic parvocellular neurones in the paraventricular nucleus of rat hypothalamus. British journal of pharmacology 20061101
Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells. Naunyn-Schmiedeberg's archives of pharmacology 20061101
Phorbol ester-induced contraction through p38 mitogen-activated protein kinase is diminished in aortas from DOCA-salt hypertensive rats. Archives of pharmacal research 20061101
Aldosterone-sensitive NTS neurons are inhibited by saline ingestion during chronic mineralocorticoid treatment. Brain research 20061018
Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte. European journal of pharmacology 20061010
In vivo effects of thyroid hormone, corticosteroids and prolactin on cell proliferation and apoptosis in the anterior intestine of the euryhaline mudskipper (Periophthalmus modestus). Life sciences 20061004
Mineralocorticoid synthesis during the periovulatory interval in macaques. Biology of reproduction 20061001
SGK1 is not required for regulation of colonic ENaC activity. Pflugers Archiv : European journal of physiology 20061001
Central action of increased osmolality to support blood pressure in deoxycorticosterone acetate-salt rats. Hypertension (Dallas, Tex. : 1979) 20061001
Differences in maternal protein intake in pregnant rats alone alter the docosahexaenoic acid concentration in the fetal and adult offspring. Metabolism: clinical and experimental 20061001
A fission yeast-based test system for the determination of IC50 values of anti-prostate tumor drugs acting on CYP21. Journal of enzyme inhibition and medicinal chemistry 20061001
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma. Neurochemistry international 20060901
Abnormal renovascular parathyroid hormone-1 receptor in hypertension: Primary defect or secondary to angiotensin ii type 1 receptor activation? Endocrinology 20060901
Genotyping of five chinese patients with 17alpha-hydroxylase deficiency diagnosed through high-performance liquid chromatography serum adrenal profile: identification of two novel CYP17 mutations. The Journal of clinical endocrinology and metabolism 20060901
The serum- and glucocorticoid-induced kinase in DOCA-salt hypertension. Journal of molecular medicine (Berlin, Germany) 20060901
Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. Journal of molecular medicine (Berlin, Germany) 20060901
Kindling-induced alterations in GABAA receptor-mediated inhibition and neurosteroid activity in the rat piriform cortex. The European journal of neuroscience 20060901
Increased reactive oxygen species contributes to kidney injury in mineralocorticoid hypertensive rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901
GABAergic tonic inhibition of substantia gelatinosa neurons in mouse spinal cord. Neuroreport 20060821
Deoxycorticosterone's anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin. Experimental neurology 20060801
In the ventral tegmental area, progestins have actions at D1 receptors for lordosis of hamsters and rats that involve GABA A receptors. Hormones and behavior 20060801
Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats. British journal of pharmacology 20060801
Plasma pregnenolone levels in cynomolgus monkeys following pharmacological challenges of the hypothalamic-pituitary-adrenal axis. Pharmacology, biochemistry, and behavior 20060801
Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder. Journal of clinical psychopharmacology 20060801
Plastic neuronal changes in GABA(A) receptor gene expression induced by progesterone metabolites: in vitro molecular and functional studies. Pharmacology, biochemistry, and behavior 20060801
Tonic GABA(A) receptor-mediated currents in human brain. The European journal of neuroscience 20060801
Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. Pharmacology, biochemistry, and behavior 20060801
The effect of hypertension on serum nitric oxide and vascular endothelial growth factor concentrations. A study in DOCA-Salt hypertensive ovariectomized rats. Regulatory peptides 20060715
Mineralocorticoid receptor blockade but not steroid withdrawal reverses renal fibrosis in deoxycorticosterone/salt rats. Endocrinology 20060701
Arterial 5-hydroxytryptamine transporter function is impaired in deoxycorticosterone acetate and Nomega-nitro-L-arginine but not spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20060701
Serum- and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance. Diabetes 20060701
Attenuation of cardiovascular remodeling in DOCA-salt rats by the vasopeptidase inhibitor, omapatrilat. Clinical and experimental hypertension (New York, N.Y. : 1993) 20060701
Design of an Escherichia coli system for whole cell mediated steroid synthesis and molecular evolution of steroid hydroxylases. Journal of biotechnology 20060625
Hypothalamic-pituitary-adrenal axis and ethanol modulation of deoxycorticosterone levels in cynomolgus monkeys. Psychopharmacology 20060601
Role of fibrillin-1 in hypertensive and diabetic glomerular disease. American journal of physiology. Renal physiology 20060601
Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension. American journal of physiology. Heart and circulatory physiology 20060601
Long-term administration of rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20060601
Extrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats. Hypertension (Dallas, Tex. : 1979) 20060601
Abnormalities of the hippocampus are similar in deoxycorticosterone acetate-salt hypertensive rats and spontaneously hypertensive rats. Journal of neuroendocrinology 20060601
Epidermal growth factor induces vasoconstriction through the phosphatidylinositol 3-kinase-mediated mitogen-activated protein kinase pathway in hypertensive rats. Journal of pharmacological sciences 20060601
The effects of deoxycorticosterone-induced sodium appetite on hedonic behaviors in the rat. Behavioral neuroscience 20060601
[Deoxycorticosterone-producing adrenal tumor]. Nihon rinsho. Japanese journal of clinical medicine 20060528
[Aldosterone synthase deficiency]. Nihon rinsho. Japanese journal of clinical medicine 20060528
Multiple corticosteroid receptors in fish: from old ideas to new concepts. General and comparative endocrinology 20060515
Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity. Psychoneuroendocrinology 20060501
Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis. Psychopharmacology 20060501
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. Journal of molecular medicine (Berlin, Germany) 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Contribution of central nitric oxide to the regulation of blood pressure and sodium balance in DOCA-salt hypertension. Journal of cardiovascular pharmacology 20060501
Requirements for a high rate of potassium excretion in rats consuming a low electrolyte diet. The Journal of physiology 20060415
Evolution. Reducible complexity. Science (New York, N.Y.) 20060407
Evolution of hormone-receptor complexity by molecular exploitation. Science (New York, N.Y.) 20060407
Deoxycorticosterone acetate-salt rats: hypertension and sympathoexcitation driven by increased NaCl levels. Hypertension (Dallas, Tex. : 1979) 20060401
Deoxycorticosterone inactivation by AKR1C3 in human mineralocorticoid target tissues. Molecular and cellular endocrinology 20060327
Serum level of vascular endothelial growth factor is increased by estrogen replacement therapy in normotensive and DOCA-Salt hypertensive ovariectomized rats. Clinica chimica acta; international journal of clinical chemistry 20060301
Superoxide anion is elevated in sympathetic neurons in DOCA-salt hypertension via activation of NADPH oxidase. American journal of physiology. Heart and circulatory physiology 20060301
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. The Journal of pharmacology and experimental therapeutics 20060301
Mineralocorticoid receptor activation causes cerebral vessel remodeling and exacerbates the damage caused by cerebral ischemia. Hypertension (Dallas, Tex. : 1979) 20060301
Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20060301
Hydration of rainbow trout oocyte during meiotic maturation and in vitro regulation by 17,20{beta}-dihydroxy-4-pregnen-3-one and cortisol. The Journal of experimental biology 20060301
Rosuvastatin attenuates hypertension-induced cardiovascular remodeling without affecting blood pressure in DOCA-salt hypertensive rats. Journal of cardiovascular pharmacology 20060301
Three novel point mutations of the CYP21 gene detected in classical forms of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20060301
Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms. Clinical science (London, England : 1979) 20060201
c-Jun N-terminal kinase contributes to norepinephrine-induced contraction through phosphorylation of caldesmon in rat aortic smooth muscle. Journal of pharmacological sciences 20060201
Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Regulatory peptides 20060115
Aldosterone target neurons in the nucleus tractus solitarius drive sodium appetite. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111
Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues. The Journal of steroid biochemistry and molecular biology 20060101
Bifunctional gonadotropin-releasing hormone antagonist-progesterone analogs with increased efficacy and duration of action. Endocrinology 20060101
Action of two neuroactive steroids against motor seizures induced by pentetrazol in rats during ontogeny. Physiological research 20060101
Physiological role of adrenal deoxycorticosterone-derived neuroactive steroids in stress-sensitive conditions. Neuroscience 20060101
DOCA-induced phosphorylation of glycogen synthase kinase 3beta. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
A missing link between a high salt intake and blood pressure increase. Journal of pharmacological sciences 20060101
Synthesis and evaluation of some 1,2,3,4-tetrahydropyrimidine-2-thione and condensed pyrimidine derivatives as potential antihypertensive agents. Arzneimittel-Forschung 20060101
Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls. Prostaglandins, leukotrienes, and essential fatty acids 20060101
Anticonvulsant action of three neurosteroids against cortical epileptic afterdischarges in immature rats. Brain research bulletin 20051230
Molecular identity and gene expression of aldosterone synthase cytochrome P450. Biochemical and biophysical research communications 20051209
The aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart. Endocrinology 20051201
Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension. Hypertension (Dallas, Tex. : 1979) 20051201
Evolution of liver antioxidant status and iron implication during the development of deoxycorticosterone-saline hypertension in rats. Biological trace element research 20051201
The acute anticonvulsant effects of deoxycorticosterone in developing rats: role of metabolites and mineralocorticoid-receptor responses. Epilepsia 20051201
NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)alpha-mediated cardiovascular effects. Mutation research 20051111
Reversal of cardiac dysfunction by selective ET-A receptor antagonism. British journal of pharmacology 20051101
Mineralocorticoids decrease the activity of the apical small-conductance K channel in the cortical collecting duct. American journal of physiology. Renal physiology 20051101
Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20051101
A rat model of preeclampsia. Clinical and experimental hypertension (New York, N.Y. : 1993) 20051101
Internal sodium balance in DOCA-salt rats: a body composition study. American journal of physiology. Renal physiology 20051001
l-Arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20051001
Role of renal nerves in development of hypertension in DOCA-salt model in rats: a telemetric approach. American journal of physiology. Heart and circulatory physiology 20051001
Pharmacokinetic changes of DA-8159, a new erectogenic, and one of its metabolites, DA-8164 after intravenous and oral administration of DA-8159 to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats. Biopharmaceutics & drug disposition 20051001
Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension. Journal of hypertension 20051001
Exaggerated liver injury induced by ischemia-reperfusion in spontaneously hypertensive rats. American journal of hypertension 20051001
6,19-Sulfur-bridged progesterone analogues with antiimmunosuppressive activity. Journal of medicinal chemistry 20050908
Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis. American journal of physiology. Heart and circulatory physiology 20050901
Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats. American journal of physiology. Renal physiology 20050901
High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists. Neuropharmacology 20050901
Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats. Journal of neurophysiology 20050901
Steroid signalling in the ovarian surface epithelium. Trends in endocrinology and metabolism: TEM 20050901
Potassium supplementation reduces cardiac and renal hypertrophy independent of blood pressure in DOCA/salt mice. Hypertension (Dallas, Tex. : 1979) 20050901
Antihypertensive and endothelium-dependent vasodilator effects of Alpinia zerumbet, a medicinal plant. Journal of cardiovascular pharmacology 20050901
Concurrent administration of aqueous Azadirachta indica (neem) leaf extract with DOCA-salt prevents the development of hypertension and accompanying electrocardiogram changes in the rat. Phytotherapy research : PTR 20050901
Alpha-1B adrenoceptors mediate neurogenic constriction in mesenteric arteries of normotensive and DOCA-salt hypertensive mice. Autonomic neuroscience : basic & clinical 20050831
Chronic treatment with mianserin prevents DOCA-salt hypertension in rats--evidence for the involvement of central 5-HT2 receptors. European journal of pharmacology 20050822
The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11beta-hydroxylase) inhibitors. The Journal of steroid biochemistry and molecular biology 20050801
SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess. American journal of physiology. Regulatory, integrative and comparative physiology 20050801
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats. Peptides 20050801
[Deoxycorticosterone]. Nihon rinsho. Japanese journal of clinical medicine 20050801
Systemic ethanol administration elevates deoxycorticosterone levels and chronic ethanol exposure attenuates this response. Brain research 20050705
The residue E351 is essential for the activity of human 21-hydroxylase: evidence from a naturally occurring novel point mutation compared with artificial mutants generated by single amino acid substitutions. Journal of molecular medicine (Berlin, Germany) 20050701
Role of calcitonin gene-related peptide in hypertension-induced renal damage. Hypertension (Dallas, Tex. : 1979) 20050701
Differential expression and function of beacon in the rat adrenal cortex and medulla. International journal of molecular medicine 20050701
Blood pressure variability, cardiac baroreflex sensitivity and organ damage in experimentally hypertensive rats. Clinical and experimental pharmacology & physiology 20050701
Plasma concentrations of anxiolytic neuroactive steroids in men with panic disorder. Psychiatry research 20050630
Tricaprylin microemulsion for oral delivery of low molecular weight heparin conjugates. Journal of controlled release : official journal of the Controlled Release Society 20050620
Glomerular permeability defect in hypertension is dependent on renin angiotensin system activation. American journal of hypertension 20050601
Vascular reactivity of mesenteric arteries and veins to endothelin-1 in a murine model of high blood pressure. Vascular pharmacology 20050601
Do mammalian cytochrome P450s show multiple ligand access pathways and ligand channelling? EMBO reports 20050601
Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats. European journal of pharmacology 20050509
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry 20050505
High-salt diet inhibits expression of angiotensin type 2 receptor in resistance arteries. Hypertension (Dallas, Tex. : 1979) 20050501
Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension. Journal of hypertension 20050501
Muscle arteriolar and venular reactivity in two models of hypertensive rats. Microvascular research 20050501
Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Circulation research 20050401
The human mineralocorticoid receptor only partially differentiates between different ligands after expression in fission yeast. FEMS yeast research 20050401
Enhanced hypotensive effects of the essential oil of Ocimum gratissimum leaves and its main constituent, eugenol, in DOCA-salt hypertensive conscious rats. Planta medica 20050401
Rapid non-genomic effect of glucocorticoid metabolites and neurosteroids on the gamma-aminobutyric acid-A receptor. The European journal of neuroscience 20050401
Development of models for cytochrome P450 2A5 as well as two of its mutants. Die Pharmazie 20050401
Role of activation function domain-1, DNA binding, and coactivator GRIP1 in the expression of partial agonist activity of glucocorticoid receptor-antagonist complexes. Biochemistry 20050308
Antihypertensive effect of 5-HT1A agonist buspirone and 5-HT2B antagonists in experimentally induced hypertension in rats. Pharmacology 20050301
Attenuating 5alpha-pregnane-3alpha-ol-20-one formation in the hippocampus of female rats increases pentylenetetrazole-induced seizures. Epilepsy & behavior : E&B 20050301
Historic perspectives and recent advances in major animal models of hypertension. Acta pharmacologica Sinica 20050301
Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20050201
The potential advantage of omapatrilat: dual anti-fibrotic and anti-inflammatory effects in one single molecule. Journal of hypertension 20050201
Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats. Journal of hypertension 20050201
Sodium preference and appetite in rats in an operant protocol. Physiology & behavior 20050117
Type 10 17beta-hydroxysteroid dehydrogenase catalyzing the oxidation of steroid modulators of gamma-aminobutyric acid type A receptors. Molecular and cellular endocrinology 20050114
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries. American journal of physiology. Heart and circulatory physiology 20050101
Panic induction with cholecystokinin-tetrapeptide (CCK-4) Increases plasma concentrations of the neuroactive steroid 3alpha, 5alpha tetrahydrodeoxycorticosterone (3alpha, 5alpha-THDOC) in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101
Functional characterization of two novel point mutations in the CYP21 gene causing simple virilizing forms of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism 20050101
11-deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor. Endocrinology 20050101
Calcitonin gene-related peptide protects against hypertension-induced heart and kidney damage. Hypertension (Dallas, Tex. : 1979) 20050101
Preliminary evidence for an association between aggressive and hostile behaviour and 3alpha,5alpha-tetrahydroprogesterone plasma levels in schizophrenia. Journal of psychiatry & neuroscience : JPN 20050101
Adrenocortical carcinoma producing 11-deoxycorticosterone: a rare cause of mineralocorticoid hypertension. Journal of endocrinological investigation 20050101
Progression of renal damage in the obese Zucker rat in response to deoxycorticosterone acetate-salt-induced hypertension. Annals of clinical and laboratory science 20050101
Involvement of marinobufagenin in a rat model of human preeclampsia. American journal of nephrology 20050101
[Specific features of diagnosis of hormonal insufficiency in patients with tumors of the adrenal cortex]. Vestnik khirurgii imeni I. I. Grekova 20050101
Biochemical characterization of the Arctic char (Salvelinus alpinus) ovarian progestin membrane receptor. Reproductive biology and endocrinology : RB&E 20050101
The angiotensin-II (AT-II) receptor blocker olmesartan reduces renal damage in animal models of hypertension and diabetes. Proceedings of the Western Pharmacology Society 20050101
[The role of neurosteroids in the central nervous system function]. Przeglad lekarski 20050101
[Perspectives of neurosteroid derivative application in antiepileptic therapy]. Przeglad lekarski 20050101
Effect of pregnancy and 5alpha-pregnan-3alpha-ol-20-one on atrial receptor afferent discharge in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20041201
Origin of aldosterone in the rat heart. Endocrinology 20041101
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Journal of cardiovascular pharmacology 20041101
The effect of Sutherlandia frutescens on steroidogenesis: confirming indigenous wisdom. Endocrine research 20041101
Systemic hemodynamics in non-anesthetized L-NAME- and DOCA-salt-treated mice. Journal of hypertension 20041001
Altered expression of the delta subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929
Mechanism for aldosterone potentiation of angiotensin II-stimulated rat arterial smooth muscle cell proliferation. Hypertension (Dallas, Tex. : 1979) 20040901
Renal endothelin receptor type B upregulation in rats with low or high renin hypertension. Journal of hypertension 20040901
Effects of the active neurosteroid allotetrahydrodeoxycorticosterone on long-term potentiation in the rat hippocampus: implications for depression. Progress in neuro-psychopharmacology & biological psychiatry 20040901
Do human vascular endothelial cells produce aldosterone? Endocrinology 20040801
Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. Journal of clinical psychopharmacology 20040801
Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects. Clinical endocrinology 20040801
Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats. Endocrinology 20040701
Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C. European journal of pharmacology 20040628
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension. The Journal of pharmacology and experimental therapeutics 20040601
Nitric oxide synthase expression in AT2 receptor-deficient mice after DOCA-salt. Kidney international 20040601
The effect of estrogen on serum nitric oxide concentrations in normotensive and DOCA Salt hypertensive ovariectomized rats. Clinica chimica acta; international journal of clinical chemistry 20040601
The serotonin transporter is present and functional in peripheral arterial smooth muscle. Journal of cardiovascular pharmacology 20040601
Lack of defects in androgen production in children with hypospadias. The Journal of clinical endocrinology and metabolism 20040601
Effect of a methionine-supplemented diet on the blood pressure of Sprague-Dawley and deoxycorticosterone acetate-salt hypertensive rats. The British journal of nutrition 20040601
Expression of cytochrome P450c17 and other steroid-converting enzymes in the rat kidney throughout the life-span. The Journal of steroid biochemistry and molecular biology 20040601
Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits. FEBS letters 20040521
Heme oxygenase-mediated endothelial dysfunction in DOCA-salt, but not in spontaneously hypertensive, rat arterioles. American journal of physiology. Heart and circulatory physiology 20040501
Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20040501
p38 mitogen-activated protein kinase contributes to the diminished aortic contraction by endothelin-1 in DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20040501
Increased O2*- production and upregulation of ETB receptors by sympathetic neurons in DOCA-salt hypertensive rats. Hypertension (Dallas, Tex. : 1979) 20040501
Tranilast attenuates myocardial fibrosis in association with suppression of monocyte/macrophage infiltration in DOCA/salt hypertensive rats. Journal of hypertension 20040501
Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway. Journal of the American College of Cardiology 20040421
Impaired function of alpha2-adrenergic autoreceptors on sympathetic nerves associated with mesenteric arteries and veins in DOCA-salt hypertension. American journal of physiology. Heart and circulatory physiology 20040401
Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension. The Journal of pharmacology and experimental therapeutics 20040401
ETA receptor mediates altered leukocyte-endothelial cell interaction and adhesion molecules expression in DOCA-salt rats. Hypertension (Dallas, Tex. : 1979) 20040401
PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit? Hypertension (Dallas, Tex. : 1979) 20040401
Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil. Planta medica 20040401
Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats. Molecular and cellular biochemistry 20040401
Glomerulosa function and aldosterone synthesis in the rat. Molecular and cellular endocrinology 20040331
The regulation of aldosterone synthase expression. Molecular and cellular endocrinology 20040331
Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats. Clinical science (London, England : 1979) 20040301
Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol. Fertility and sterility 20040301
Systematic investigation of different steroid precursors with respect to their effect on superoxide anion production by human neutrophil granulocytes. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040301
Effects of deoxycorticosterone on renal vascular reactivity and flow-pressure curve in spontaneously hypertensive rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301
Determination of cardiac contractility in awake unsedated mice with a fluid-filled catheter. American journal of physiology. Heart and circulatory physiology 20040201
Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats. Hypertension (Dallas, Tex. : 1979) 20040201
Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA-salt hypertensive rats. British journal of pharmacology 20040201
Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats. European journal of pharmacology 20040126
Low [Mg2+]e enhances arterial spontaneous tone via phosphatidylinositol 3-kinase in DOCA-salt hypertension. Hypertension (Dallas, Tex. : 1979) 20040101
Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism. Journal of human hypertension 20040101
How could aortic arginase activity enhancement be involved in DOCA-salt hypertension? Clinical and experimental hypertension (New York, N.Y. : 1993) 20040101
The role of chloride in deoxycorticosterone hypertension: selective sodium loading by diet or drinking fluid. Physiological research 20040101
Plasma concentrations of anxiolytic neurosteroids in men with normal anxiety scores: a correlation analysis. Neuropsychobiology 20040101
Mineralocorticoid treatment upregulates the hypothalamic vasopressinergic system of spontaneously hypertensive rats. Neuroendocrinology 20040101
[Neurobiology of depression and stress syndromes. Focus on active neurosteroids and neurosteroids]. Vertex (Buenos Aires, Argentina) 20040101
Coronary vascular and aortic endothelial permeability during estrogen therapy: a study in DOCA-salt hypertensive ovariectomized rats. Physiological research 20040101
In the ventral tegmental area, G-proteins and cAMP mediate the neurosteroid 3alpha,5alpha-THP's actions at dopamine type 1 receptors for lordosis of rats. Neuroendocrinology 20040101
Mineralocorticoids act centrally to regulate blood-borne tumor necrosis factor-alpha in normal rats. American journal of physiology. Regulatory, integrative and comparative physiology 20031201
Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells. Naunyn-Schmiedeberg's archives of pharmacology 20031201
Blood pressure effects of intravenous apomorphine in conscious deoxycorticosterone-acetate salt-hypertensive rats. Journal of cardiovascular pharmacology 20031201
Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats. Biological & pharmaceutical bulletin 20031201
Flexibility of the endogenous progesterone lactonisation pathway in Aspergillus tamarii KITA: transformation of a series of cortical steroid analogues. The Journal of steroid biochemistry and molecular biology 20031201
Reference values for urinary steroids in Japanese newborn infants: gas chromatography/mass spectrometry in selected ion monitoring. Endocrine journal 20031201
Fluoxetine may influence lordosis of rats through effects on midbrain 3 alpha,5 alpha-THP concentrations. Annals of the New York Academy of Sciences 20031201
Omapatrilat increases renal endothelin in deoxycorticosterone acetate-salt hypertensive rats. Vascular pharmacology 20031201
Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns. The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126
Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension. European journal of pharmacology 20031114
Effects of olanzapine infusions to the ventral tegmental area on lordosis and midbrain 3alpha,5alpha-THP concentrations in rats. Psychopharmacology 20031101
Regulation of renal cortical cyclooxygenase-2 in young rats. American journal of physiology. Renal physiology 20031101
Endothelin-1 stimulates arterial VCAM-1 expression via NADPH oxidase-derived superoxide in mineralocorticoid hypertension. Hypertension (Dallas, Tex. : 1979) 20031101
Activity of the basolateral K+ channels is coupled to the Na+-K+-ATPase in the cortical collecting duct. American journal of physiology. Renal physiology 20031101
Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 Via NF-kappaB induced by oxidative stress. Hypertension (Dallas, Tex. : 1979) 20031101
[HIV-positive patient with multiple ulcers. Lues maligna]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20031101
Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. Acta physiologica Scandinavica 20031101
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. Journal of medicinal chemistry 20031023
Steroid 21-hydroxylase expression in cultured rat astrocytes. Brain research bulletin 20031015
Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension. Hypertension (Dallas, Tex. : 1979) 20031001
ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension. Hypertension (Dallas, Tex. : 1979) 20031001
Down-regulation of soluble guanylyl cyclase in the inner medulla of DOCA-salt hypertensive rats. Vascular pharmacology 20031001
Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031001
Interrenal steroid 21-hydroxylase in eels: primary structure, progesterone-specific activity and enhanced expression by ACTH. Journal of molecular endocrinology 20031001
Antioxidant status in the liver of hypertensive and metallothionein-deficient mice. Canadian journal of physiology and pharmacology 20031001
Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension. Circulation 20030909
Altering cortisol level does not change the pleasurable effects of methamphetamine in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension. Hypertension (Dallas, Tex. : 1979) 20030901
Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension. Hypertension (Dallas, Tex. : 1979) 20030901
Mineralocorticoid action and sodium-hydrogen exchange: studies in experimental cardiac fibrosis. Endocrinology 20030901
Ghrelin, an endogenous ligand for the growth hormone-secretagogue receptor, is expressed in the human adrenal cortex. International journal of molecular medicine 20030801
Renal inactivation, mineralocorticoid generation, and 11beta-hydroxysteroid dehydrogenase inhibition ameliorate the antimineralocorticoid effect of progesterone in vivo. The Journal of clinical endocrinology and metabolism 20030801
Chronic endopeptidase inhibition in DOCA-salt hypertension: mechanism of cardiovascular protection. Clinical and experimental hypertension (New York, N.Y. : 1993) 20030801
Determination of 3-keto-4-ene steroids and their hydroxylated metabolites catalyzed by recombinant human cytochrome P450 1B1 enzyme using gas chromatography-mass spectrometry with trimethylsilyl derivatization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705
Automated coupling of capillary-HPLC to matrix-assisted laser desorption/ionization mass spectrometry for the analysis of small molecules utilizing a reactive matrix. Analytical and bioanalytical chemistry 20030701
Effect of magnesium on mRNA expression and production of endothelin-1 in DOCA-salt hypertensive rats. Journal of cardiovascular pharmacology 20030701
Hypertension superimposed on type II diabetes in Goto Kakizaki rats induces progressive nephropathy. Kidney international 20030601
Hypertension increases expression of growth factors and MHC II in chronic allograft nephropathy. Kidney international 20030601
Antihypertensive effects of the essential oil of Alpinia zerumbet and its main constituent, terpinen-4-ol, in DOCA-salt hypertensive conscious rats. Fundamental & clinical pharmacology 20030601
Involvement of mesolimbic structures in short-term sodium depletion: in situ hybridization and ligand-binding analyses. Neuroendocrinology 20030601
Neurosteroid secretion in panic disorder. Psychiatry research 20030530
Nephroprotective effects of the endothelin ET(A) receptor antagonist darusentan in salt-sensitive genetic hypertension. European journal of pharmacology 20030516
Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics. The Journal of pharmacology and experimental therapeutics 20030501
Effect of exercise training on liver antioxidant status of deoxycorticosterone acetate salt induced hypertensive rats. Canadian journal of physiology and pharmacology 20030501
Altered gene expression of adrenomedullin and its receptor system and molecular forms of tissue adrenomedullin in left ventricular hypertrophy induced by malignant hypertension. Regulatory peptides 20030415
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. The Journal of clinical investigation 20030415
PI3-kinase-induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity. Hypertension (Dallas, Tex. : 1979) 20030401
Adrenal minerlocorticoids pathway and its clinical applications. Clinica chimica acta; international journal of clinical chemistry 20030401
Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. Endocrinology 20030301
Chronic blockade of neuronal nitric oxide synthase does not affect long-term control of blood pressure in normal, saline-drinking or deoxycorticosterone-treated rats. Experimental physiology 20030301
Na/H exchange isoform 1 is involved in mineralocorticoid/salt-induced cardiac injury. Hypertension (Dallas, Tex. : 1979) 20030301
Vasopressin induces vascular superoxide via endothelin-1 in mineralocorticoid hypertension. Hypertension (Dallas, Tex. : 1979) 20030301
Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit. Journal of neurophysiology 20030301
Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions? Trends in pharmacological sciences 20030301
Norbormide enhances late steps of steroid-hormone synthesis in rat and mouse adrenal cortex. The Journal of steroid biochemistry and molecular biology 20030301
Differential alterations in sympathetic neurotransmission in mesenteric arteries and veins in DOCA-salt hypertensive rats. Autonomic neuroscience : basic & clinical 20030227
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation 20030225
Ghrelin and growth hormone secretagogue receptor are expressed in the rat adrenal cortex: Evidence that ghrelin stimulates the growth, but not the secretory activity of adrenal cells. FEBS letters 20030211
Analysis of biological samples by gas chromatography-mass spectrometry without a reference standard: measurement of urinary 18-hydroxytetrahydro-11-dehydrocorticosterone excretion rate in human subjects. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030205
Hypertension associated with reduced plasma thrombomodulin levels and a hypercoagulable state in rats. Clinical and experimental hypertension (New York, N.Y. : 1993) 20030201
Decreases in neurokinin-3 tachykinin receptor-immunoreactive and -mRNA levels are associated with salt appetite in the deoxycorticosterone-treated rat. Brain research 20030117
Effects of omapatrilat on blood pressure and renal injury in L-NAME and L-NAME plus DOCA-treated rats. American journal of hypertension 20030101
Endothelin-dependent modulation of vasoconstrictor action in the coronary circulation in early salt-induced experimental hypertension. Journal of hypertension 20030101
Contribution of endogenous endothelin in the enhanced coronary constriction in DOCA-salt hypertensive rats. Journal of hypertension 20030101
Comparison of the cardiovascular protection by omapatrilat and lisinopril treatments in DOCA-salt hypertension. Journal of hypertension 20030101
Tert-butyl hydroperoxide-mediated vascular responses in DOCA-salt hypertensive rats. Vascular pharmacology 20030101
Gender differences in the regulation of 3 alpha-hydroxysteroid dehydrogenase in rat brain and sensitivity to neurosteroid-mediated stress protection. Neuroscience 20030101
[A short summary. The history of glucocorticoids]. Pharmazie in unserer Zeit 20030101
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension. BMC pharmacology 20030101
Celiprolol inhibits mitogen-activated protein kinase and endothelin-1 and transforming growth factor-beta(1) gene in rats. European journal of pharmacology 20021220
Cardiovascular effects of the essential oil of Mentha x villosa in DOCA-salt-hypertensive rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20021201
Analysis of differential gene expression in stretched podocytes: osteopontin enhances adaptation of podocytes to mechanical stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021101
Increased sensitivity of the obese Zucker rat to deoxycorticosterone-salt-induced hypertension. Journal of hypertension 20021101
New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone. American heart journal 20021101
Cyclooxygenase-2 inhibitors attenuate increased blood pressure in renovascular hypertensive models, but not in deoxycorticosterone-salt hypertension. Hypertension research : official journal of the Japanese Society of Hypertension 20021101
Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors. Endocrine research 20021101
Endothelin-A receptor blockade prevents left ventricular hypertrophy and dysfunction in salt-sensitive experimental hypertension. Circulation 20021029
Deoxycorticosterone stimulates the activity of nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase immunoreactivity in hypothalamic nuclei of rats. Neuroscience letters 20020906
Mineralocorticoid regulation of cyclooxygenase-2 expression in rat renal medulla. American journal of physiology. Renal physiology 20020901
Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in DOCA-salt rats. American journal of physiology. Heart and circulatory physiology 20020901
Endothelin binding and calcium signalling in hypertension. Journal of hypertension 20020901
Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. Journal of hypertension 20020901
Role of sensory nervous system vasoactive peptides in hypertension. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901
Gender differences in vascular expression of endothelin and ET(A)/ET(B) receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901
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Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery. Journal of neurochemistry 20020901
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GABA(A) receptor delta subunit deletion prevents neurosteroid modulation of inhibitory synaptic currents in cerebellar neurons. Neuropharmacology 20020901
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Membrane-bound progesterone receptors coupled to G proteins in the fungus Rhizopus nigricans. FEMS microbiology letters 20020716
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The clinical potentials of endogenous neurosteroids. Drugs of today (Barcelona, Spain : 1998) 20020701
Agonistic and antagonistic properties of progesterone metabolites at the human mineralocorticoid receptor. European journal of endocrinology 20020601
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Magnesium supplementation and deoxycorticosterone acetate--salt hypertension: effect on arterial mechanical properties and on activity of endothelin-1. Canadian journal of physiology and pharmacology 20020601
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The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats. Experimental neurology 20020501
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Endothelins and venous tone in DOCA-salt hypertension. Journal of hypertension 20020401
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A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets. Brain research. Brain research protocols 20020401
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The alpha8 integrin chain affords mechanical stability to the glomerular capillary tuft in hypertensive glomerular disease. The American journal of pathology 20020301
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Gene transfer of endothelial NO synthase and manganese superoxide dismutase on arterial vascular cell adhesion molecule-1 expression and superoxide production in deoxycorticosterone acetate-salt hypertension. Arteriosclerosis, thrombosis, and vascular biology 20020201
Gas chromatography/mass spectrometry characterization of corticosteroid metabolism in human immortalized keratinocytes. The Journal of investigative dermatology 20020201
The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme. European journal of biochemistry 20020201
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Comparison of L-type and mixed L- and T-type calcium channel blockers on kidney injury caused by deoxycorticosterone-salt hypertension in rats. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201
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Changes in Fos expression in various brain regions during deoxycorticosterone acetate treatment: relation to salt appetite, vasopressin mRNA and the mineralocorticoid receptor. Neuroendocrinology 20011201
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Antihypertensive effects of chicken extract against deoxycorticosterone acetate-salt-induced hypertension in rats. Biological & pharmaceutical bulletin 20011001
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Progesterone oxidation by cytochrome P450 2D isoforms in the brain. Endocrinology 20010901
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Decreased vascular glucose transporter expression and glucose uptake in DOCA-salt hypertension. Journal of hypertension 20010901
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17alpha-hydroxylase deficiency accompanied by adrenal myelolipoma. Internal medicine (Tokyo, Japan) 20010901
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis. Toxicology 20010828
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Experimental cardiac fibrosis: differential time course of responses to mineralocorticoid-salt administration. Endocrinology 20010801
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Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010801
Effects of alpha-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats. European journal of pharmacology 20010720
Mechanisms of endothelin-1-induced potentiation of noradrenaline response in rat mesenteric artery. Clinical and experimental pharmacology & physiology 20010701
Glomerular osteopontin expression and macrophage infiltration in glomerulosclerosis of DOCA-salt rats. American journal of kidney diseases : the official journal of the National Kidney Foundation 20010701
Steroidogenesis in the human skin: 21-hydroxylation in cultured keratinocytes. The Journal of steroid biochemistry and molecular biology 20010701
Mineralocorticoid treatment attenuates activation of oxytocinergic and vasopressinergic neurons by icv ANG II. American journal of physiology. Regulatory, integrative and comparative physiology 20010601
An influence of variation in the aldosterone synthase gene (CYP11B2) on corticosteroid responses to ACTH in normal human subjects. Clinical endocrinology 20010601
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Left ventricular function in mice lacking the AT2 receptor. Journal of hypertension 20010501
Role of endothelin and vasopressin in DOCA-salt hypertension. British journal of pharmacology 20010401
Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats. Journal of hypertension 20010401
Celiprolol stimulates endothelial nitric oxide synthase expression and improves myocardial remodeling in deoxycorticosterone acetate-salt hypertensive rats. Journal of hypertension 20010401
Effects of quinapril on expression of eNOS, ACE, and AT1 receptor in deoxycorticosterone acetate-salt hypertensive rats. American journal of hypertension 20010401
Decreased influence of nitric oxide on deoxycorticosterone acetate (DOCA)-salt hypertension. American journal of hypertension 20010401
Diagnosis of adrenal cortical dysfunction by liquid chromatography-tandem mass spectrometry. Annals of clinical and laboratory science 20010401
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Effects of angiotensin-converting enzyme inhibitor and angiotensin type 1 receptor antagonist in deoxycorticosterone acetate-salt hypertensive mice lacking Ren-2 gene. Hypertension (Dallas, Tex. : 1979) 20010301
Effect of an ET(B)-selective and a mixed ET(A/B) endothelin receptor antagonist on venomotor tone in deoxycorticosterone-salt hypertension. Journal of hypertension 20010301
The genetics, pathophysiology, and management of human deficiencies of P450c17. Endocrinology and metabolism clinics of North America 20010301
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia 20010301
Disorders of mineralocorticoid synthesis. Best practice & research. Clinical endocrinology & metabolism 20010301
High-resolution mapping of the blood pressure QTL on chromosome 7 using Dahl rat congenic strains. Genomics 20010215
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A novel formulation for controlled release of heparin-DOCA conjugate dispersed as nanoparticles in polyurethane film. Biomaterials 20010201
Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response. Hypertension (Dallas, Tex. : 1979) 20010201
Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture. Environmental health perspectives 20010201
The quantification of endogenous steroids in bovine aqueous humour and vitreous humour using isotope dilution GC-NCI-MS. Journal of pharmaceutical and biomedical analysis 20010201
Strain difference (WKY, SPRD) in the hepatic antioxidant status in rat and effect of hypertension (SHR, DOCA). Ex vivo and in vitro data. Molecular and cellular biochemistry 20010201
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A proteasome inhibitor prevents vascular hypertrophy in deoxycorticosterone acetate-salt hypertensive rats. Clinical and experimental pharmacology & physiology 20010101
Age-related differences in neurosteroid potentiation of muscimol-stimulated 36Cl(-) flux following chronic ethanol treatment. Neuroscience 20010101
Expression profiles of COUP-TF, DAX-1, and SF-1 in the human adrenal gland and adrenocortical tumors: possible implications in steroidogenesis. Molecular genetics and metabolism 20010101
Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats. Pharmacology 20010101
Stress and neuroactive steroids. International review of neurobiology 20010101
Gender-related plasma levels of progesterone, interleukin-8 and interleukin-10 during and after cardiopulmonary bypass in infants and children. Critical care (London, England) 20010101
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Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and binding. The Journal of biological chemistry 20000623
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The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. Stroke 19970901
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Heme oxygenase substrates acutely lower blood pressure in hypertensive rats. The American journal of physiology 19960901
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Effects of amlodipine on glomerular filtration, growth, and injury in experimental hypertension. Hypertension (Dallas, Tex. : 1979) 19960201
Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology 19960101
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