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6320-51-0 | 2,4-Thiazolidinedione, 5-p-methoxybenzylidene-
CAS No: 6320-51-0 Catalog No: AG00ELXE MDL No:
Product Description
Catalog Number:
AG00ELXE
Chemical Name:
2,4-Thiazolidinedione, 5-p-methoxybenzylidene-
CAS Number:
6320-51-0
IUPAC Name:
5-[(4-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
InChI:
InChI=1S/C11H9NO3S/c1-15-8-4-2-7(3-5-8)6-9-10(13)12-11(14)16-9/h2-6H,1H3,(H,12,13,14)
InChI Key:
VRUKGUBMRBLJJW-UHFFFAOYSA-N
Properties
Complexity:
332
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
235.03g/mol
Formal Charge:
0
Heavy Atom Count:
16
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
235.257g/mol
Monoisotopic Mass:
235.03g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
80.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
1
XLogP3:
2.2
Literature
| Title | Journal |
|---|---|
| (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione protects rats from carbon tetrachloride-induced liver injury and fibrogenesis. | World journal of gastroenterology 20120221 |
| Development and validation of a UPLC-MS/MS method for quantification of SKLB010, an investigational anti-inflammatory compound, and its application to pharmacokinetic studies in beagle dogs. | Journal of pharmaceutical and biomedical analysis 20110910 |
| (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a novel readily available and orally active glitazone, attenuates the bleomycin-induced pulmonary fibrosis in vivo. | Biological & pharmaceutical bulletin 20110101 |
| Pleiotropic effects of glitazones: a double edge sword? | Frontiers in pharmacology 20110101 |
| (Z)-5-(4-methoxybenzylidene) thiazolidine-2, 4-dione ameliorates the adjuvant-induced arthritis via inhibiting the migration of macrophage and down-regulating the cytokine mRNA expression. | International immunopharmacology 20101101 |
| Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice. | Journal of medicinal chemistry 20100114 |
| [SKLB-102 inhibits acute hepatitis induced by concanavalin A in mice]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090701 |
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