200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 631-69-6
631-69-6 | b-Boswellic acid
CAS No: 631-69-6 Catalog No: AG003OJP MDL No:MFCD04039448
Product Description
Catalog Number:
AG003OJP
Chemical Name:
b-Boswellic acid
CAS Number:
631-69-6
Molecular Formula:
C30H48O3
Molecular Weight:
456.7003
MDL Number:
MFCD04039448
IUPAC Name:
(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid
InChI:
InChI=1S/C30H48O3/c1-18-10-13-26(3)16-17-28(5)20(24(26)19(18)2)8-9-21-27(4)14-12-23(31)30(7,25(32)33)22(27)11-15-29(21,28)6/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21-,22-,23-,24+,26-,27-,28-,29-,30-/m1/s1
InChI Key:
NBGQZFQREPIKMG-PONOSELZSA-N
SMILES:
C[C@@H]1CC[C@]2([C@@H]([C@H]1C)C1=CC[C@H]3[C@@]([C@@]1(CC2)C)(C)CCC1[C@]3(C)CC[C@H]([C@]1(C)C(=O)O)O)C
UNII:
B252M1YO2V
Properties
Complexity:
878
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
11
Defined Bond Stereocenter Count:
0
Exact Mass:
456.36g/mol
Formal Charge:
0
Heavy Atom Count:
33
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
456.711g/mol
Monoisotopic Mass:
456.36g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
57.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
8.3
Literature
| Title | Journal |
|---|---|
| The synergistic effect of beta-boswellic acid and Nurr1 overexpression on dopaminergic programming of antioxidant glutathione peroxidase-1-expressing murine embryonic stem cells. | Neuroscience 20121011 |
| Boswellic acids from frankincense inhibit lipopolysaccharide functionality through direct molecular interference. | Biochemical pharmacology 20120101 |
| [Chemopreventive effect of boswellic acid and curcumin on 7,12-dimethyl benzanthracene-induced hamster cheek pouch carcinogenesis]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20111101 |
| Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer. | Investigational new drugs 20111001 |
| The 'MESACA' study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis. | Advances in therapy 20111001 |
| A cyano analogue of boswellic acid induces crosstalk between p53/PUMA/Bax and telomerase that stages the human papillomavirus type 18 positive HeLa cells to apoptotic death. | European journal of pharmacology 20110625 |
| Development and evaluation of vesicular system for curcumin delivery. | Archives of dermatological research 20110301 |
| Two new triterpenoids from the resin of Boswellia carterii. | Journal of Asian natural products research 20110301 |
| Complexation with phosphatidyl choline as a strategy for absorption enhancement of boswellic acid. | Drug delivery 20101101 |
| Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense. | Journal of immunology (Baltimore, Md. : 1950) 20090901 |
| LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells. | Anticancer research 20090801 |
| Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1. | Molecular cancer research : MCR 20090101 |
| Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells. | Lipids in health and disease 20090101 |
| Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. | Bioorganic & medicinal chemistry 20080915 |
| A simple high-performance liquid chromatographic method for the estimation of boswellic acids from the market formulations containing Boswellia serrata extract. | Journal of chromatographic science 20080901 |
| Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601 |
| The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601 |
| Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids. | Biochemical pharmacology 20080115 |
| Boswellic acids and glucosamine show synergistic effect in preclinical anti-inflammatory study in rats. | Bioorganic & medicinal chemistry letters 20070701 |
| CEC and EKC of natural compounds. | Electrophoresis 20070601 |
| Natural products as a gold mine for arthritis treatment. | Current opinion in pharmacology 20070601 |
| Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. | Journal of ethnopharmacology 20060919 |
| Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase. | Molecular pharmacology 20060901 |
| Separation and quantification of terpenoids of Boswellia serrata Roxb. extract by planar chromatography techniques (TLC and AMD). | Journal of separation science 20060901 |
| Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid. | British journal of pharmacology 20051001 |
| Boswellia carterii extract inhibits TH1 cytokines and promotes TH2 cytokines in vitro. | Clinical and diagnostic laboratory immunology 20050501 |
| Effects of Boswellia serrata in mouse models of chemically induced colitis. | American journal of physiology. Gastrointestinal and liver physiology 20050401 |
| Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. | Molecular cancer therapeutics 20050301 |
| Bioactive constituents from Boswellia papyrifera. | Journal of natural products 20050201 |
| Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. | British journal of pharmacology 20040101 |
| Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb. | Indian journal of experimental biology 20031201 |
| Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. | Cancer detection and prevention 20030101 |
| Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. | Carcinogenesis 20021201 |
| Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway. | International journal of molecular medicine 20021001 |
| Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. | Anticancer research 20020101 |
| [Therapy of active Crohn disease with Boswellia serrata extract H 15]. | Zeitschrift fur Gastroenterologie 20010101 |
| Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha. | Molecular pharmacology 20000701 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.