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624-49-7 | (E)-Dimethyl fumarate
CAS No: 624-49-7 Catalog No: AG003PM2 MDL No:MFCD00064438
Product Description
Catalog Number:
AG003PM2
Chemical Name:
(E)-Dimethyl fumarate
CAS Number:
624-49-7
Molecular Formula:
C6H8O4
Molecular Weight:
144.1253
MDL Number:
MFCD00064438
IUPAC Name:
dimethyl (E)-but-2-enedioate
InChI:
InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
InChI Key:
LDCRTTXIJACKKU-ONEGZZNKSA-N
SMILES:
COC(=O)/C=C/C(=O)OC
EC Number:
210-849-0
UNII:
FO2303MNI2
Properties
Complexity:
141
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1
Exact Mass:
144.042g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
144.126g/mol
Monoisotopic Mass:
144.042g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
52.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.7
Literature
| Title | Journal |
|---|---|
| Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. | Science (New York, N.Y.) 20180427 |
| Metformin, A New Era for an Old Drug in the Treatment of Immune Mediated Disease? | Current drug targets 20180101 |
| Dimethyl fumarate influences innate and adaptive immunity in multiple sclerosis. | Journal of autoimmunity 20180101 |
| Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress. | The Journal of pharmacology and experimental therapeutics 20171001 |
| Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes. | Molecular and cellular biology 20170601 |
| Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells. | Science signaling 20160913 |
| Disease modifying therapies for relapsing multiple sclerosis. | BMJ (Clinical research ed.) 20160822 |
| Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20160608 |
| Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. | The Journal of biological chemistry 20160212 |
| Preventing Allograft Rejection by Targeting Immune Metabolism. | Cell reports 20151027 |
| Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. | Pharmacological research 20131001 |
| Dimethyl fumarate - only an anti-psoriatic medication? | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20121101 |
| Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. | The New England journal of medicine 20120920 |
| Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. | The New England journal of medicine 20120920 |
| The 'poison chair' treatment for multiple sclerosis. | The New England journal of medicine 20120920 |
| Validation of the multiple sensor mechanism of the Keap1-Nrf2 system. | Free radical biology & medicine 20120815 |
| Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling. | The Journal of biological chemistry 20120810 |
| Drugs: An injection of hope. | Nature 20120412 |
| Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. | Cell metabolism 20120307 |
| Effect of BG-12 on contrast-enhanced lesions in patients with relapsing--remitting multiple sclerosis: subgroup analyses from the phase 2b study. | Multiple sclerosis (Houndmills, Basingstoke, England) 20120301 |
| Safety profiles come to fore as more drugs approach MS market. | Nature biotechnology 20120109 |
| Dimethyl fumarate contact dermatitis of the foot: an increasingly widespread disease. | International journal of dermatology 20120101 |
| Effects of dimethyl fumarate on neuroprotection and immunomodulation. | Journal of neuroinflammation 20120101 |
| Allergic contact dermatitis from dimethyl fumarate after contact with a Chinese sofa. | Journal of cutaneous medicine and surgery 20120101 |
| Dimethylfumarate attenuates renal fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling. | PloS one 20120101 |
| Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters. | International journal of molecular sciences 20120101 |
| Determination of dimethyl fumarate in desiccant and antimould sachets by reversed-phase liquid chromatography. | Biomedical chromatography : BMC 20111201 |
| IκBα glutathionylation and reduced histone H3 phosphorylation inhibit eotaxin and RANTES. | The European respiratory journal 20111201 |
| Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions. | Experimental dermatology 20111201 |
| Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection. | Journal of immunology (Baltimore, Md. : 1950) 20111115 |
| Oral treatment for multiple sclerosis. | The Lancet. Neurology 20111101 |
| [New information about fumaric acid esters (Fumaderm): results of a workshop of experts]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20110901 |
| Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear. | Contact dermatitis 20110801 |
| A Summary of shoe allergic contact dermatitis caused by dimethyl fumarate in Spain. | Contact dermatitis 20110801 |
| Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110701 |
| Contact dermatitis caused by dimethylfumarate in Argentina. | Clinical toxicology (Philadelphia, Pa.) 20110701 |
| Dimethylfumarate inhibits angiogenesis in vitro and in vivo: a possible role for its antipsoriatic effect? | The Journal of investigative dermatology 20110601 |
| Suppression of VEGFR2 expression in human endothelial cells by dimethylfumarate treatment: evidence for anti-angiogenic action. | The Journal of investigative dermatology 20110601 |
| Mechanisms of drug action: the potential of dimethylfumarate for the treatment of neoplasms. | The Journal of investigative dermatology 20110601 |
| Fumarate esters as angiogenesis inhibitors: key to action in psoriasis? | The Journal of investigative dermatology 20110601 |
| Trial watch: Phase III success for Biogen's oral multiple sclerosis therapy. | Nature reviews. Drug discovery 20110601 |
| Survey of dimethyl fumarate in desiccant products during 2009 in Italy. | Bulletin of environmental contamination and toxicology 20110401 |
| BG-12 reduces evolution of new enhancing lesions to T1-hypointense lesions in patients with multiple sclerosis. | Journal of neurology 20110301 |
| Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. | Brain : a journal of neurology 20110301 |
| Treatment of recurrent aphthous stomatitis with fumaric acid esters. | Archives of dermatology 20110301 |
| [Current treatment of multiple sclerosis]. | Lege artis medicinae : uj magyar orvosi hirmondo 20110201 |
| Oral therapies for multiple sclerosis: a review of agents in phase III development or recently approved. | CNS drugs 20110101 |
| Leucoderma after Chinese sofa dermatitis. | Contact dermatitis 20110101 |
| Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells. | PloS one 20110101 |
| Dimethyl fumarate. | Dermatitis : contact, atopic, occupational, drug 20110101 |
| Dimethyl fumarate: a human health hazard. | Dermatitis : contact, atopic, occupational, drug 20110101 |
| Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease. | PloS one 20110101 |
| The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1. | ASN neuro 20110101 |
| Cytokine secretion pattern in treatment of lymphocytes of multiple sclerosis patients with fumaric acid esters. | Immunological investigations 20110101 |
| Determination of dimethyl fumarate (DMFu) in silica gel pouches using gas chromatography coupled ion trap mass spectrometry. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20110101 |
| Globalisation and allergy. | European journal of dermatology : EJD 20110101 |
| Epidemiological description of an outbreak of dermatitis related to dimethylfumarate, France, 2008. | Archives of environmental & occupational health 20110101 |
| Dimethyl fumarate for multiple sclerosis. | Expert opinion on investigational drugs 20101201 |
| Sofa dermatitis. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20101101 |
| Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling. | American journal of physiology. Cell physiology 20101001 |
| Persistent shoe dermatitis caused by dimethyl fumarate. | Acta dermato-venereologica 20100901 |
| [Allergic contact dermatitis due to shoes with dimethylfumarate]. | Medicina clinica 20100619 |
| [Allergic contact dermatitis due to dimethyl fumarate in boots]. | Actas dermo-sifiliograficas 20100501 |
| An outbreak of furniture related dermatitis ('sofa dermatitis') in Finland and the UK: history and clinical cases. | Journal of the European Academy of Dermatology and Venereology : JEADV 20100401 |
| Combination of dacarbazine and dimethylfumarate efficiently reduces melanoma lymph node metastasis. | The Journal of investigative dermatology 20100401 |
| [Contact dermatitis due to dimethyl fumarate]. | Actas dermo-sifiliograficas 20100401 |
| Sofa dermatitis presenting as a chronic treatment resistant dermatitis. | Irish medical journal 20100401 |
| Allergic contact dermatitis to shoes induced by dimethylfumarate: A new allergen imported from China. | Dermatology online journal 20100315 |
| Treatment of severe, recalcitrant, chronic plaque psoriasis with fumaric acid esters: a prospective study. | The British journal of dermatology 20100201 |
| Sensitization to dimethyl fumarate with multiple concurrent patch test reactions. | Contact dermatitis 20100201 |
| Allergic contact dermatitis to dimethyl fumarate in footwear. | Contact dermatitis 20100201 |
| An epidemic of furniture-related dermatitis: searching for a cause. | The British journal of dermatology 20100101 |
| Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation. | Journal of neuroinflammation 20100101 |
| Dimethylfumarate for psoriasis: Pronounced effects on lesional T-cell subsets, epidermal proliferation and differentiation, but not on natural killer T cells in immunohistochemical study. | American journal of clinical dermatology 20100101 |
| Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse. | PloS one 20100101 |
| Multiple sclerosis therapies: molecular mechanisms and future. | Results and problems in cell differentiation 20100101 |
| DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1. | Respiratory research 20100101 |
| Inhibition of NF-κB and AP-1 by dimethylfumarate correlates with down-regulated IL-6 secretion and proliferation in human lung fibroblasts. | Swiss medical weekly 20100101 |
| A case of contact dermatitis to dimethylfumarate in shoes identified in Italy. | Annali dell'Istituto superiore di sanita 20100101 |
| Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure. | Contact dermatitis 20091101 |
| Dimethylfumarate inhibits tumor cell invasion and metastasis by suppressing the expression and activities of matrix metalloproteinases in melanoma cells. | Cell biology international 20091001 |
| Gas-chromatography-mass spectrometry analysis of dimethyl fumarate in consumer products. | Journal of chromatography. A 20090925 |
| Dimethylfumarate inhibits NF-{kappa}B function at multiple levels to limit airway smooth muscle cell cytokine secretion. | American journal of physiology. Lung cellular and molecular physiology 20090801 |
| Determination of dimethyl fumarate and other potential allergens in desiccant and antimould sachets. | Analytical and bioanalytical chemistry 20090801 |
| Occupational allergic contact dermatitis associated with dimethyl fumarate in clothing. | Contact dermatitis 20090801 |
| Determination of dimethyl fumarate in desiccant and mouldproof agents using ultrasound-assisted extraction gas chromatography with electron-capture detection. | Journal of chromatography. A 20090724 |
| Efficacy and safety of fumaric acid esters in the long-term treatment of psoriasis--a retrospective study (FUTURE). | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090701 |
| Contact dermatitis to dimethylfumarate in armchairs. | Allergy 20090501 |
| [Lichenoid dermatitis resulting from sensitization to dimethylfumarate: atypical presentation of 'Chinese sofa dermatitis']. | Annales de dermatologie et de venereologie 20090301 |
| [Acute dimethylfumarate-induced eczema on the foot]. | Annales de dermatologie et de venereologie 20090301 |
| Molecular mechanisms of Nrf2-mediated antioxidant response. | Molecular carcinogenesis 20090201 |
| Computational evaluation of enantioselective Diels-Alder reactions mediated by Corey's cationic oxazaborolidine catalysts. | The Journal of organic chemistry 20090116 |
| Detection of metabolites of fumaric acid esters in human urine: implications for their mode of action. | The Journal of investigative dermatology 20090101 |
| Phytochemical induction of cell cycle arrest by glutathione oxidation and reversal by N-acetylcysteine in human colon carcinoma cells. | Nutrition and cancer 20090101 |
| Treatment of disseminated granuloma annulare with low-dose fumaric acid. | Acta dermato-venereologica 20090101 |
| The derivatization of bioplatform molecules by using KF/alumina catalysis. | ChemSusChem 20090101 |
| The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. | Biochemical and biophysical research communications 20081031 |
| Oral fumarate for relapsing-remitting multiple sclerosis. | Lancet (London, England) 20081025 |
| Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. | Lancet (London, England) 20081025 |
| Beneficial effects of dimethyl fumarate on experimental autoimmune myocarditis. | Archives of medical research 20081001 |
| The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer. | The British journal of dermatology 20080701 |
| Dimethyl fumarate, a small molecule drug for psoriasis, inhibits Nuclear Factor-kappaB and reduces myocardial infarct size in rats. | European journal of pharmacology 20080531 |
| Dimethylfumarate reduces leukocyte rolling in vivo through modulation of adhesion molecule expression. | The Journal of investigative dermatology 20080201 |
| [Fumaric acid and its esters in the treatment of multiple sclerosis: studies and effects]. | Der Nervenarzt 20080201 |
| Fumaric acid esters. | Clinics in dermatology 20080101 |
| Experimental and computational evidence for alpha-lactone intermediates in the addition of aqueous bromine to disodium dimethyl-maleate and -fumarate. | Organic & biomolecular chemistry 20071221 |
| Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism. | Journal of thrombosis and haemostasis : JTH 20071201 |
| Drug evaluation: BG-12, an immunomodulatory dimethylfumarate. | Current opinion in investigational drugs (London, England : 2000) 20071101 |
| [Modulatory effect of fumaric acid esters on superoxide-anion generation in human phagocytes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20071101 |
| A salutary case of Fumaderm potentially masking the symptoms of bowel cancer and partial bowel obstruction. | The British journal of dermatology 20071001 |
| Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect. | The Journal of investigative dermatology 20070901 |
| Treatment of psoriasis with fumaric acid esters (Fumaderm). | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20070801 |
| Dimethylfumarate inhibits nuclear binding of nuclear factor kappaB but not of nuclear factor of activated T cells and CCAAT/enhancer binding protein beta in activated human T cells. | The British journal of dermatology 20070501 |
| Novel oral agents for multiple sclerosis. | Current neurology and neuroscience reports 20070501 |
| Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1. | The Journal of investigative dermatology 20070401 |
| Improvement of noninfectious uveitis with fumaric acid esters: results of a pilot study. | Archives of ophthalmology (Chicago, Ill. : 1960) 20070401 |
| Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters. | Bioorganic & medicinal chemistry 20070101 |
| Use of fumaric acid esters in psoriasis. | Indian journal of dermatology, venereology and leprology 20070101 |
| Dimethylfumarate impairs melanoma growth and metastasis. | Cancer research 20061215 |
| Therapeutic potential of selectin antagonists in psoriasis. | Expert opinion on investigational drugs 20060801 |
| Treatment of therapy-resistant Alopecia areata with fumaric acid esters. | European journal of medical research 20060731 |
| Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration. | Clinical and experimental immunology 20060701 |
| Oral fumaric acid esters for the treatment of active multiple sclerosis: an open-label, baseline-controlled pilot study. | European journal of neurology 20060601 |
| Modest induction of phase 2 enzyme activity in the F-344 rat prostate. | BMC cancer 20060101 |
| Chemistry of Ru(eta6-1,3,5-cyclooctatriene)(eta2-dimethyl fumarate)2. | Chemical record (New York, N.Y.) 20060101 |
| Evidence of covalent interaction of fumaric acid esters with sulfhydryl groups in peptides. | Journal of mass spectrometry : JMS 20051001 |
| Improvement of herpetic stromal keratitis with fumaric acid derivate is associated with systemic induction of T helper 2 cytokines. | Clinical and experimental immunology 20051001 |
| Fumaric acid esters in necrobiosis lipoidica: results of a prospective noncontrolled study. | The British journal of dermatology 20051001 |
| Enhancement of antibacterial superoxide-anion generation in human monocytes by fumaric acid esters. | Archives of dermatological research 20051001 |
| Detoxication enzyme inducers modify cytokine production in rat mixed glial cells. | Journal of neuroimmunology 20050901 |
| Fumaric acid esters for severe psoriasis: a retrospective review of 58 cases. | The British journal of dermatology 20050901 |
| Effect of inducers of DT-diaphorase on the haemolytic activity and nephrotoxicity of 2-amino-1,4-naphthoquinone in rats. | Chemico-biological interactions 20050815 |
| Inhibition of vesicular monoamine transporter enhances vulnerability of dopaminergic cells: relevance to Parkinson's disease. | Neurochemistry international 20050301 |
| Enhanced cytotoxicity of bioreductive antitumor agents with dimethyl fumarate in human glioblastoma cells. | Anti-cancer drugs 20050201 |
| Fumaric acid esters therapy: a new treatment modality in pityriasis rubra pilaris? | The British journal of dermatology 20050201 |
| Dimethylfumarate for psoriasis: more than a dietary curiosity. | Trends in molecular medicine 20050101 |
| Disseminated granuloma annulare--treatment with fumaric acid esters. | Dermatology (Basel, Switzerland) 20050101 |
| BG 12: BG 00012, BG 12/Oral Fumarate, FAG-201, second-generation fumarate derivative--Fumapharm/Biogen Idec. | Drugs in R&D 20050101 |
| Identification of anti-inflammatory drugs according to their capacity to suppress type-1 and type-2 T cell profiles. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041201 |
| Dietary induction of NQO1 increases the antitumour activity of mitomycin C in human colon tumours in vivo. | British journal of cancer 20041018 |
| Influence of dimethylfumarate on experimental HSV-1 necrotizing keratitis. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20041001 |
| [Successful treatment of skin and lung sarcoidosis with fumaric acid ester]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040601 |
| Fumaric acid esters, their place in the treatment of psoriasis. | The British journal of dermatology 20040401 |
| Fumaric acid esters in the treatment of psoriasis: an Italian experience. | The Journal of dermatological treatment 20040101 |
| In vitro pharmacokinetics of anti-psoriatic fumaric acid esters. | BMC pharmacology 20040101 |
| Dimethylfumarate is a potent inducer of apoptosis in human T cells. | The Journal of investigative dermatology 20031201 |
| Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters. | Biopharmaceutics & drug disposition 20030901 |
| Efficacy of fumaric acid ester monotherapy in psoriasis pustulosa palmoplantaris. | The British journal of dermatology 20030701 |
| Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030601 |
| Radiation response of cells during altered protein thiol redox. | Radiation research 20030401 |
| [Vision disorders in therapy with fumaric acid esters?]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20030301 |
| Clearance of necrobiosis lipoidica with fumaric acid esters. | Dermatology (Basel, Switzerland) 20030101 |
| Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells. | Journal of immunology (Baltimore, Md. : 1950) 20020501 |
| Topical calcipotriol plus oral fumaric acid is more effective and faster acting than oral fumaric acid monotherapy in the treatment of severe chronic plaque psoriasis vulgaris. | Dermatology (Basel, Switzerland) 20020101 |
| Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters. | BMC dermatology 20020101 |
| Experimental therapies for psoriasis. | Archivum immunologiae et therapiae experimentalis 20020101 |
| Dimethylfumarate inhibits tumor-necrosis-factor-induced CD62E expression in an NF-kappa B-dependent manner. | The Journal of investigative dermatology 20011201 |
| The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells. | The British journal of dermatology 20010601 |
| Inhibition of Escherichia coli by dimethyl fumarate. | International journal of food microbiology 20010411 |
| Preferential expression of antioxidant response element mediated gene expression in astrocytes. | Journal of neurochemistry 20010301 |
| [Granuloma annulare disseminatum: successful therapy with fumaric acid ester]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010301 |
| [Effects of chemical agents on the prevention of fungal contamination during household wheat storage in Cixian county]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20010301 |
| Dimethylfumarate is an inhibitor of cytokine-induced nuclear translocation of NF-kappa B1, but not RelA in normal human dermal fibroblast cells. | The Journal of investigative dermatology 20010101 |
| Dithranol and dimethylfumarate suppress the interferon-gamma-induced up-regulation of cytokeratin 17 as a putative psoriasis autoantigen in vitro. | Skin pharmacology and applied skin physiology 20010101 |
| Addition of pentoxifylline could reduce the side effects of fumaric acid esters in the treatment of psoriasis. | Acta dermato-venereologica 20010101 |
| Antifungal properties of 2-bromo-3-fluorosuccinic acid esters and related compounds. | Journal of medicinal chemistry 19770401 |
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