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623-05-2

623-05-2 | 4-Hydroxybenzyl alcohol

CAS No: 623-05-2 Catalog No: AG003425 MDL No:MFCD00004658

Product Description

Catalog Number:
AG003425
Chemical Name:
4-Hydroxybenzyl alcohol
CAS Number:
623-05-2
Molecular Formula:
C7H8O2
Molecular Weight:
124.1372
MDL Number:
MFCD00004658
IUPAC Name:
4-(hydroxymethyl)phenol
InChI:
InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2
InChI Key:
BVJSUAQZOZWCKN-UHFFFAOYSA-N
SMILES:
OCc1ccc(cc1)O
EC Number:
210-768-0
UNII:
1A3AH1FP1B
NSC Number:
227926
FEMA Number:
3987

Properties

Complexity:
75  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
124.052g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
124.139g/mol
Monoisotopic Mass:
124.052g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
40.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2  

Literature

Title Journal
The implication of mediators for enhancement of laccase oxidation of sulfonamide antibiotics. Bioresource technology 20120601
Modulation of LPS-stimulated neuroinflammation in BV-2 microglia by Gastrodia elata: 4-hydroxybenzyl alcohol is the bioactive candidate. Journal of ethnopharmacology 20120131
Novel chalcone-based fluorescent human histamine h(3) receptor ligands as pharmacological tools. Frontiers in systems neuroscience 20120101
In vitro and in vivo evaluation of the anti-angiogenic actions of 4-hydroxybenzyl alcohol. British journal of pharmacology 20110601
Reduction of oxidative stress by p-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant. Biomaterials 20110401
Multiple multi-copper oxidase gene families in basidiomycetes - what for? Current genomics 20110401
p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia. Molecules and cells 20110331
Gastrodia Elata Bl Attenuates Cocaine-Induced Conditioned Place Preference and Convulsion, but not Behavioral Sensitization in Mice: Importance of GABA(A) Receptors. Current neuropharmacology 20110301
Effects of gastrodia elata bl on phencyclidine-induced schizophrenia-like psychosis in mice. Current neuropharmacology 20110301
4-hydroxybenzyl alcohol ameliorates cerebral injury in rats by antioxidant action. Neurochemical research 20110201
Linking NE1545 gene expression with cell volume changes in Nitrosomonas europaea cells exposed to aromatic hydrocarbons. Chemosphere 20110101
Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit. The FEBS journal 20110101
Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. Chinese medicine 20110101
Chemiluminescent nanomicelles for imaging hydrogen peroxide and self-therapy in photodynamic therapy. Journal of biomedicine & biotechnology 20110101
Gastrodin inhibits expression of inducible NO synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-stimulated microglia via MAPK pathways. PloS one 20110101
Isolation and characterization of novel bacterial strains exhibiting ligninolytic potential. BMC biotechnology 20110101
Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer. Nature chemical biology 20101201
[Constituents of Gymnadenia conopsea]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
Antioxidant and anti-inflammatory activities of hydroxybenzyl alcohol releasing biodegradable polyoxalate nanoparticles. Biomacromolecules 20100809
Supercritical fluid chromatography of myrosinase reaction products in ground yellow mustard seed oil. Journal of food science 20100501
Formaldehyde in the indoor environment. Chemical reviews 20100414
Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: an enzyme directed prodrug approach. Chemico-biological interactions 20100212
Secondary metabolites of the phytopathogen Peronophythora litchii. Natural product communications 20100201
Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats. Brain research 20100113
Genetic transformation of lignin degrading fungi facilitated by Agrobacterium tumefaciens. BMC biotechnology 20100101
A cascade biodegradable polymer based on alternating cyclization and elimination reactions. Journal of the American Chemical Society 20091230
The hunt for natural skin whitening agents. International journal of molecular sciences 20091201
Biosynthesis of vanillin via ferulic acid in Vanilla planifolia. Journal of agricultural and food chemistry 20091111
[Simultaneous determination of four components in Gastrodia elata by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
Metabolites from endophytic fungus S20 of Cephalotaxus hainanensis. Journal of Asian natural products research 20090801
4-(Hydroxy-meth-yl)phenol. Acta crystallographica. Section E, Structure reports online 20090701
Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin. Neuroscience research 20090601
A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola. BMC systems biology 20090101
Bazedoxifene for the prevention of postmenopausal osteoporosis. Therapeutics and clinical risk management 20081201
Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS. Journal of pharmaceutical and biomedical analysis 20081104
Microfluidic synthesis and catalytic application of PVP-stabilized, approximately 1 nm gold clusters. Langmuir : the ACS journal of surfaces and colloids 20081021
Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method. Phytomedicine : international journal of phytotherapy and phytopharmacology 20081001
[Brain targeting of gastrodin nasal in situ gel]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080501
Biotransformation and pharmacokinetics of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside, an antioxidant isolated from Origanum vulgare. Journal of agricultural and food chemistry 20080423
The photo-Favorskii reaction of p-hydroxyphenacyl compounds is initiated by water-assisted, adiabatic extrusion of a triplet biradical. Journal of the American Chemical Society 20080319
Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration. Journal of drug targeting 20080201
Distribution and metabolism of gastrodin in rat brain. Journal of pharmaceutical and biomedical analysis 20080122
Engineering and Applications of fungal laccases for organic synthesis. Microbial cell factories 20080101
Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia. Brain research 20071121
Host plant-dependent metabolism of 4-hydroxybenzylglucosinolate in Pieris rapae: substrate specificity and effects of genetic modification and plant nitrile hydratase. Insect biochemistry and molecular biology 20071101
Studies on the antioxidant activities of natural vanilla extract and its constituent compounds through in vitro models. Journal of agricultural and food chemistry 20070919
Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol. The Journal of pharmacy and pharmacology 20070901
[Studies on chemical constituents from root of Cynanchum atratum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901
Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis. Biological & pharmaceutical bulletin 20070601
Synthesis and biological evaluation of 12 allenic aromatic ethers. Bioorganic & medicinal chemistry letters 20070515
[Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS]. Yao xue xue bao = Acta pharmaceutica Sinica 20070401
Phenolic constituents from the rhizomes of Gastrodia elata. Natural product research 20070201
Development and validation of an RP-HPLC method for quantitative determination of vanillin and related phenolic compounds in Vanilla planifolia. Journal of separation science 20070101
Chemical fingerprint analysis of rhizomes of Gymnadenia conopsea by HPLC-DAD-MSn. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205
A new citryl glycoside from Gastrodia elata and its inhibitory activity on GABA transaminase. Chemical & pharmaceutical bulletin 20061201
Anti-inflammatory action of phenolic compounds from Gastrodia elata root. Archives of pharmacal research 20061001
[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium]. Yao xue xue bao = Acta pharmaceutica Sinica 20061001
[Production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension cultures of Datura tatula L]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060901
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorganic & medicinal chemistry letters 20060201
Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice. Biological & pharmaceutical bulletin 20060201
Bioactivation of 4-methylphenol (p-cresol) via cytochrome P450-mediated aromatic oxidation in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 20051201
Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake. Journal of agricultural and food chemistry 20051116
Gastrodia elata blume and an active component, p-hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions. Biological & pharmaceutical bulletin 20050601
In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism. The Journal of pharmacology and experimental therapeutics 20050301
New phenolic glycosides from the seeds of Cucurbita moschata. Chemical & pharmaceutical bulletin 20050201
Metabolism of gallic acid and catechin by Lactobacillus hilgardii from wine. Journal of agricultural and food chemistry 20041020
Chemical constituents of the rhizomes of Coeloglossum viride var. bracteatum. Journal of Asian natural products research 20040301
[Chemical constituents from the rhizoma of Arundina graminifolia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040201
Metabolism of benzyl alcohol via catechol ortho-pathway in methylnaphthalene-degrading Pseudomonas putida CSV86. Applied microbiology and biotechnology 20031001
Substituent effects on carbocation stability: the pK(R) for p-quinone methide. Journal of the American Chemical Society 20030723
4-Hydroxybenzyl alcohol accumulates in flowers and developing fruits of carrot and inhibits seed formation. Journal of plant physiology 20030601
Polymer-supported reagents for methylphosphorylation and phosphorylation of carbohydrates. Bioorganic & medicinal chemistry letters 20020722
Flash photolytic generation and study of p-quinone methide in aqueous solution. An estimate of rate and equilibrium constants for heterolysis of the carbon-bromine bond in p-hydroxybenzyl bromide. Journal of the American Chemical Society 20020605
In vitro effects of hydroxybenzaldehydes from Gastrodia elata and their analogues on GABAergic neurotransmission, and a structure-activity correlation. Planta medica 20011201
Evidence of a new biotransformation pathway of p-coumaric acid into p-hydroxybenzaldehyde in Pycnoporus cinnabarinus. Applied microbiology and biotechnology 20011201
Identification of novel polyphenol oxidase inhibitors by enzymatic one-pot synthesis and deconvolution of combinatorial libraries. Biotechnology and bioengineering 20011005
Studies on the reaction of p-hydroxybenzyl alcohol and hydroxyl radicals. Journal of chromatographic science 20010901
Determination of the active ingredients in Gastrodia rhizoma by capillary electrophoresis with electrochemical detection. The Analyst 20010901
Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function. The Plant cell 20010701
Properties of diphenolase from Vanilla planifolia (Andr.) shoot primordia cultured in vitro. Journal of agricultural and food chemistry 20010701
Simultaneous determination of p-hydroxybenzaldehyde, p-hydroxybenzyl alcohol, 4-(beta-D-glucopyranosyloxy)-benzyl alcohol, and sugars in Gastrodia elata blume measured as their acetylated derivatives by GC-MS. Journal of chromatographic science 20010601
Effects of noncovalent and covalent FAD binding on the redox and catalytic properties of p-cresol methylhydroxylase. Biochemistry 20010220
A germacranolide and three hydroxybenzyl alcohol derivatives from Hieracium murorum and Crepis bocconi. Phytochemical analysis : PCA 20010101
Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats. Journal of ethnopharmacology 19970301
Effects of Gastrodia elata and its active constituents on scopolamine-induced amnesia in rats. Planta medica 19960801
p-Hydroxybenzyl alcohol attenuates learning deficits in the inhibitory avoidance task: involvement of serotonergic and dopaminergic systems. The Chinese journal of physiology 19960101

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