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Home > Imidazoles > 615-16-7
615-16-7 | 2H-Benzimidazol-2-one, 1,3-dihydro-
CAS No: 615-16-7 Catalog No: AG00IAVM MDL No:MFCD00127894
Product Description
Catalog Number:
AG00IAVM
Chemical Name:
2H-Benzimidazol-2-one, 1,3-dihydro-
CAS Number:
615-16-7
Molecular Formula:
C7H6N2O
Molecular Weight:
134.1353
MDL Number:
MFCD00127894
IUPAC Name:
1,3-dihydrobenzimidazol-2-one
InChI:
InChI=1S/C7H6N2O/c10-7-8-5-3-1-2-4-6(5)9-7/h1-4H,(H2,8,9,10)
InChI Key:
SILNNFMWIMZVEQ-UHFFFAOYSA-N
SMILES:
O=c1[nH]c2c([nH]1)cccc2
EC Number:
210-412-4
UNII:
CV8118UZEW
Properties
Complexity:
142
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
134.048g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
134.138g/mol
Monoisotopic Mass:
134.048g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
41.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1
Literature
| Title | Journal |
|---|---|
| Aza-oxindole synthesis via base promoted Truce-Smiles rearrangement. | Chemical communications (Cambridge, England) 20121118 |
| 1-Octyl-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Aza-oxindole synthesis by oxidative coupling of C(sp2)-H and C(sp3)-H centers. | Chemical communications (Cambridge, England) 20120325 |
| 1,3-Dibenzyl-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20111201 |
| 5-Chloro-1-nonyl-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20111201 |
| 1-Decyl-6-nitro-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20111101 |
| Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA. | Organic letters 20111021 |
| Synthesis and Diels-Alder cycloadditions of exo-imidazolidin-2-one dienes. | The Journal of organic chemistry 20111007 |
| Receptor-based QSAR study for a series of 3,3-disubstituted-5-aryl oxindoles and 6-aryl benzimidazol-2-ones derivatives as progesterone receptor inhibitors. | SAR and QSAR in environmental research 20111001 |
| 1-Benzyl-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20110701 |
| Potassium hydroxide/dimethyl sulfoxide promoted intramolecular cyclization for the synthesis of benzimidazol-2-ones. | Organic letters 20110603 |
| 1,3-Bis(prop-2-yn-yl)-1H-1,3-benzimid-azol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20110501 |
| 1-Nonyl-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20110201 |
| 1,3-Bis[2-(2-oxo-1,3-oxazolidin-3-yl)eth-yl]-1H-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20110201 |
| A classification study of respiratory Syncytial Virus (RSV) inhibitors by variable selection with random forest. | International journal of molecular sciences 20110101 |
| An inducible expression system of the calcium-activated potassium channel 4 to study the differential impact on embryonic stem cells. | Stem cells international 20110101 |
| Isolation and characterization of Pseudomonas sp. CBW capable of degrading carbendazim. | Biodegradation 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Biodegradation of carbendazim by a novel actinobacterium Rhodococcus jialingiae djl-6-2. | Chemosphere 20101001 |
| Computational thermochemistry of six ureas, imidazolidin-2-one, N,N'-trimethyleneurea, benzimidazolinone, parabanic acid, barbital (5,5'-diethylbarbituric acid), and 3,4,4'-trichlorocarbanilide, with an extension to related compounds. | The journal of physical chemistry. A 20100902 |
| Inhibition of protein kinase C-driven nuclear factor-kappaB activation: synthesis, structure-activity relationship, and pharmacological profiling of pathway specific benzimidazole probe molecules. | Journal of medicinal chemistry 20100624 |
| Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation. | Antiviral research 20100601 |
| 1-Isopropenyl-1H-1,3-benzimidazol-2(3H)-one. | Acta crystallographica. Section E, Structure reports online 20100601 |
| Identification of potent, highly constrained CGRP receptor antagonists. | Bioorganic & medicinal chemistry letters 20100415 |
| 1-{[(Cyclo-hexyl-oxy)carbon-yl]-oxy}ethyl 3-{[2'-(2-ethyl-2H-tetra-zol-5-yl)biphenyl-4-yl]meth-yl}-2-oxo-2,3-dihydro-1H-benzimidazole-4-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20100401 |
| Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. | Bioorganic & medicinal chemistry letters 20091115 |
| 1,3-Bis(hydroxy-meth-yl)benzimidazolin-2-one. | Acta crystallographica. Section E, Structure reports online 20091101 |
| 1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors. | Journal of medicinal chemistry 20090924 |
| Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. | Bioorganic & medicinal chemistry 20090815 |
| The discovery of highly potent CGRP receptor antagonists. | Bioorganic & medicinal chemistry letters 20090101 |
| Structure-activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties. | Bioorganic & medicinal chemistry 20080315 |
| Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety. | Bioorganic & medicinal chemistry letters 20070901 |
| Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity. | Bioorganic & medicinal chemistry letters 20070815 |
| DFT studies of the structure and vibrational assignments of 4-hydroxy quinazoline and 2-hydroxy benzimidazole. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401 |
| Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties. | Bioorganic & medicinal chemistry 20070215 |
| Benzofused tricycles based on 2-quinoxalinol. | Journal of combinatorial chemistry 20070101 |
| Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo. | Bioorganic & medicinal chemistry letters 20060301 |
| Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT. | Journal of medicinal chemistry 20050505 |
| Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime). | Biochimica et biophysica acta 20041011 |
| Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives. | Bioorganic & medicinal chemistry letters 20040308 |
| A theoretical study of substituent effects on tautomerism of 2-hydroxybenzimidazoles. | Journal of molecular modeling 20031201 |
| Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition. | Journal of the American Chemical Society 20030514 |
| Preparation of oxime dual NK(1)/NK(2) antagonists with reduced NK(3) affinity. | Bioorganic & medicinal chemistry letters 20020902 |
| New generation dopaminergic agents. Part 8: heterocyclic bioisosteres that exploit the 7-OH-2-(aminomethyl)chroman D(2) template. | Bioorganic & medicinal chemistry letters 20020211 |
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