200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 59803-98-4
59803-98-4 | UK 14,304
CAS No: 59803-98-4 Catalog No: AG003OJU MDL No:MFCD00153878
Product Description
Catalog Number:
AG003OJU
Chemical Name:
UK 14,304
CAS Number:
59803-98-4
Molecular Formula:
C11H10BrN5
Molecular Weight:
292.1346
MDL Number:
MFCD00153878
IUPAC Name:
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
InChI:
InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
InChI Key:
XYLJNLCSTIOKRM-UHFFFAOYSA-N
SMILES:
Brc1c(ccc2c1nccn2)NC1=NCCN1
UNII:
E6GNX3HHTE
NSC Number:
318825
Properties
Complexity:
308
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
291.012g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
292.14g/mol
Monoisotopic Mass:
291.012g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
62.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6
Literature
| Title | Journal |
|---|---|
| Dilute brimonidine to improve patient comfort and subconjunctival hemorrhage after LASIK. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20130701 |
| Selective loss of basal but not receptor-stimulated relaxation by endothelial nitric oxide synthase after isolation of the mouse aorta. | European journal of pharmacology 20121205 |
| Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes? | Diabetologia 20121101 |
| [Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections]. | Journal francais d'ophtalmologie 20121001 |
| Risk factors for visual field progression in the low-pressure glaucoma treatment study. | American journal of ophthalmology 20121001 |
| [Pharmacological profile and clinical efficacy of brimonidine tartrate (AIPHAGAN(®) ophthalmic solution 0.1%)]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20121001 |
| Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. | ACS nano 20120925 |
| Combining the isoabsorptive point in the ratio spectrum and the smart ratio difference methods for a single step determination of compounds with overlapped spectra. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901 |
| The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats. | European journal of pharmacology 20120805 |
| Evaluation of extended release brimonidine intravitreal device in normotensive rabbit eyes. | Acta ophthalmologica 20120801 |
| Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs. | Nanomedicine : nanotechnology, biology, and medicine 20120701 |
| [Central corneal thickness and corneal endothelial morphology with and without therapy using commercially available antiglaucomatous drugs]. | Klinische Monatsblatter fur Augenheilkunde 20120701 |
| [Effect of topical 0.1% brimonidine tartrate and 0.5% timolol maleate on pulmonary and cardiovascular functions]. | Nippon Ganka Gakkai zasshi 20120701 |
| Alpha2C-adrenoceptors play a prominent role in sympathetic constriction of porcine pulmonary arteries. | Naunyn-Schmiedeberg's archives of pharmacology 20120601 |
| A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study. | Ophthalmic epidemiology 20120601 |
| Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma. | Investigative ophthalmology & visual science 20120601 |
| Expression of the Na+-K+-2Cl(-)-cotransporter 2 in the normal and pressure-induced ischemic rat retina. | Korean journal of ophthalmology : KJO 20120601 |
| Characterization of α(2B)-adrenoceptor ligand binding in the presence of muscarinic toxin α and delineation of structural features of receptor binding selectivity. | European journal of pharmacology 20120515 |
| The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain. | Psychopharmacology 20120501 |
| Brimonidine (Alphagan) associated anterior uveitis. | The British journal of ophthalmology 20120501 |
| Fixed-combination brimonidine-timolol versus latanoprost in glaucoma and ocular hypertension: a 12-week, randomized, comparison study. | Current medical research and opinion 20120501 |
| Presynaptic inhibition of glutamate transmission by α2 receptors in the VTA. | The European journal of neuroscience 20120501 |
| Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy. | Current medical research and opinion 20120401 |
| Effects of crystalloid versus colloid and the α-2 agonist brimonidine versus placebo on intraocular pressure during prone spine surgery: a factorial randomized trial. | Anesthesiology 20120401 |
| Latanoprost versus timolol as first choice therapy in patients with ocular hypertension. A cost-effectiveness analysis. | Acta ophthalmologica 20120301 |
| Once-daily topical brimonidine tartrate gel 0·5% is a novel treatment for moderate to severe facial erythema of rosacea: results of two multicentre, randomized and vehicle-controlled studies. | The British journal of dermatology 20120301 |
| [Effect of brimonidine on central corneal thickness]. | Klinische Monatsblatter fur Augenheilkunde 20120301 |
| Recent clinical pearls from clinical trials in glaucoma. | Current opinion in ophthalmology 20120301 |
| Sustained ocular delivery of brimonidine tartrate using ion activated in situ gelling system. | Current drug delivery 20120301 |
| Strabismus surgery hemostasis. | Ophthalmology 20120301 |
| Prevalence of eye disease in Brazilian patients with psoriatic arthritis. | Clinics (Sao Paulo, Brazil) 20120301 |
| The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma. | Acta ophthalmologica 20120201 |
| Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma. | Eye (London, England) 20120101 |
| Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma. | Advances in therapy 20120101 |
| Ocular medicines in children: the regulatory situation related to clinical research. | BMC pediatrics 20120101 |
| Topiramate and the vision: a systematic review. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Short-term visual outcomes of Boston keratoprosthesis type I in saudi arabia. | Middle East African journal of ophthalmology 20120101 |
| Expression profile of inflammatory cytokines in aqueous from glaucomatous eyes. | Molecular vision 20120101 |
| Prophylactic ocular hypotensives before Nd:YAG laser posterior capsulotomy. | Journal of pharmacology & pharmacotherapeutics 20120101 |
| Authors' reply. | Journal of pharmacology & pharmacotherapeutics 20120101 |
| Intraocular pressure reduction of fixed combination timolol maleate 0.5% and dorzolamide 2% (Cosopt) administered three times a day. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Comparing the efficacy of the monocular trial treatment paradigm with multiple measurements of intraocular pressure before and after treatment initiation in primary open-angle glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| New approaches and potential treatments for dry age-related macular degeneration. | Arquivos brasileiros de oftalmologia 20120101 |
| Multicenter, prospective, open-label, observational study of bimatoprost 0.01% in patients with primary open-angle glaucoma or ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Comparison of timolol 0.5% + brimonidine 0.2% + dorzolamide 2% versus timolol 0.5% + brimonidine 0.2% in a Mexican population with primary open-angle glaucoma or ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury. | PloS one 20120101 |
| Severe ocular hypertension secondary to systemic corticosteroid treatment in a child with nephrotic syndrome. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%. | Journal of clinical pharmacology 20111201 |
| Brimonidine tartrate-eudragit long-acting nanoparticles: formulation, optimization, in vitro and in vivo evaluation. | AAPS PharmSciTech 20111201 |
| Biodegradable ocular inserts for sustained delivery of brimonidine tartarate: preparation and in vitro/in vivo evaluation. | AAPS PharmSciTech 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Prevention of retinal ganglion cell swelling by systemic brimonidine in a rat experimental glaucoma model. | Clinical & experimental ophthalmology 20111101 |
| Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats. | Upsala journal of medical sciences 20111101 |
| A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-pressure Glaucoma Treatment Study. | American journal of ophthalmology 20111101 |
| α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking. | Biological psychiatry 20111015 |
| Measurement of adherence to brimonidine therapy for glaucoma using electronic monitoring. | Journal of glaucoma 20111001 |
| Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes. | Ophthalmology 20111001 |
| Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma. | Experimental eye research 20111001 |
| Effect of brimonidine on corneal thickness. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20111001 |
| Update on the role of alpha-agonists in glaucoma management. | Experimental eye research 20110901 |
| A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy. | Brain : a journal of neurology 20110901 |
| Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma. | Current eye research 20110901 |
| [Pupillary block acute glaucoma due to acrylic intraocular lens posterior dislocation after Nd:YAG capsulotomy]. | Archivos de la Sociedad Espanola de Oftalmologia 20110901 |
| Effect of brimonidine on retinal blood flow autoregulation in primary open-angle glaucoma. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110801 |
| Laser peripheral iridotomy with iridoplasty in primary angle closure suspect: anterior chamber analysis by pentacam. | Korean journal of ophthalmology : KJO 20110801 |
| Chitosan nanoparticles for controlled delivery of brimonidine tartrate to the ocular membrane. | Die Pharmazie 20110801 |
| Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
| Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database. | The British journal of ophthalmology 20110701 |
| Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats. | Investigative ophthalmology & visual science 20110701 |
| Effects of brimonidine timolol fixed combination therapy on anterior ocular segment configuration. | Japanese journal of ophthalmology 20110701 |
| Glaucoma in a patient with nanophthalmos. | Journal of ophthalmic & vision research 20110701 |
| Adherence with brimonidine in patients with glaucoma aware and not aware of electronic monitoring. | Acta ophthalmologica 20110601 |
| Nanovesicular formulation of brimonidine tartrate for the management of glaucoma: in vitro and in vivo evaluation. | AAPS PharmSciTech 20110601 |
| Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies. | Investigative ophthalmology & visual science 20110501 |
| A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study. | American journal of ophthalmology 20110401 |
| [Benzalkonium chloride daily dose--an important criterion in glaucoma treatment]. | Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20110401 |
| Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies. | Progress in retinal and eye research 20110301 |
| Neuroprotection in glaucoma: recent and future directions. | Current opinion in ophthalmology 20110301 |
| Effect of brimonidine tartrate 0.10% ophthalmic solution on pupil diameter. | Journal of cataract and refractive surgery 20110301 |
| Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion. | Investigative ophthalmology & visual science 20110203 |
| Effect of prophylactic topical brimonidine (0.15%) administration on the development of subconjunctival hemorrhage after intravitreal injection. | Retina (Philadelphia, Pa.) 20110201 |
| Nonarteritic anterior ischemic optic neuropathy. | Current treatment options in neurology 20110201 |
| Effect of a fixed brimonidine-timolol combination on intraocular pressure after phacoemulsification. | Journal of cataract and refractive surgery 20110201 |
| Ocular perforation by an acupuncture needle. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20110201 |
| SLT and adjunctive medical therapy: a prediction rule analysis. | Journal of glaucoma 20110101 |
| Control of intraocular pressure and fluctuation with fixed-combination brimonidine-timolol versus brimonidine or timolol monotherapy. | American journal of ophthalmology 20110101 |
| Neuroprotection in glaucoma. | Indian journal of ophthalmology 20110101 |
| Lasers in primary open angle glaucoma. | Indian journal of ophthalmology 20110101 |
| Update on congenital glaucoma. | Indian journal of ophthalmology 20110101 |
| Management of angle closure glaucoma. | Indian journal of ophthalmology 20110101 |
| Medical management of glaucoma: principles and practice. | Indian journal of ophthalmology 20110101 |
| Normal-tension glaucoma (Low-tension glaucoma). | Indian journal of ophthalmology 20110101 |
| Efficacy of bimatoprost 0.03% in reducing intraocular pressure in patients with 360° synechial angle-closure glaucoma: a preliminary study. | Indian journal of ophthalmology 20110101 |
| Impact of early rise of intraocular pressure on visual outcome following diabetic vitrectomy. | Indian journal of ophthalmology 20110101 |
| The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension. | Journal of glaucoma 20110101 |
| Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons. | Molecular neurodegeneration 20110101 |
| Oxidative DNA damage and total antioxidant status in glaucoma patients. | Molecular vision 20110101 |
| Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside. | Journal of ophthalmology 20110101 |
| Refractory topiramate-induced angle-closure glaucoma in a man: a case report. | Journal of medical case reports 20110101 |
| Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells. | Cell communication and signaling : CCS 20110101 |
| Bilateral angle-closure glaucoma in a young female receiving cabergoline: a case report. | Case reports in ophthalmology 20110101 |
| Randomized trial comparing three fixed combinations of prostaglandins/prostamide with timolol maleate. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Surgical technique: complex glaucoma case requiring Molteno drainage tube extension. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Late-onset anterior dislocation of a posterior chamber intraocular lens in a patient with pseudoexfoliation syndrome. | Case reports in ophthalmology 20110101 |
| An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury. | Molecular vision 20110101 |
| [Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma]. | Srpski arhiv za celokupno lekarstvo 20110101 |
| Bilateral progressive visual loss in an epileptic, mentally retarded boy. | Middle East African journal of ophthalmology 20110101 |
| Short-term effect of topical antiglaucoma medication on tear-film stability, tear secretion, and corneal sensitivity in healthy subjects. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Neuroprotective effect of hyperbaric oxygen therapy on anterior ischemic optic neuropathy. | Frontiers in neurology 20110101 |
| The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial. | Trials 20110101 |
| Pregnancy and glaucoma. | Survey of ophthalmology 20110101 |
| Novel ocular antihypertensive compounds in clinical trials. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Primary phacoemulsification and intraocular lens implantation for acute primary angle-closure. | PloS one 20110101 |
| Densiron 68 as an intraocular tamponade for complex inferior retinal detachments. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Inflammatory glaucoma. | Oman journal of ophthalmology 20110101 |
| Activation of extracellular-signal regulated kinase by platelet-derived growth factor is potentiated by phenylephrine in primary cultures of adult rat hepatocytes. | Biological & pharmaceutical bulletin 20110101 |
| Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy. | Journal of pharmacology & pharmacotherapeutics 20110101 |
| Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line. | Journal of biomedicine & biotechnology 20110101 |
| Activation of extracellular-signal regulated kinase by epidermal growth factor is potentiated by cAMP-elevating agents in primary cultures of adult rat hepatocytes. | Biological & pharmaceutical bulletin 20110101 |
| Objective assessment of compliance and persistence among patients treated for glaucoma and ocular hypertension: a systematic review. | Patient preference and adherence 20110101 |
| Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma. | Molecular vision 20110101 |
| DPOFA, a Cl⁻/HCO₃⁻ exchanger antagonist, stimulates fluid absorption across basolateral surface of the retinal pigment epithelium. | BMC ophthalmology 20110101 |
| Challenges in the clinical measurement of ocular surface disease in glaucoma patients. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Retinal degenerations: genetics, mechanisms, and therapies. | Journal of ophthalmology 20110101 |
| Lens epithelial cell death secondary to acanthamoeba keratitis: absence of capsular bag opacification six years after cataract surgery. | Case reports in ophthalmology 20110101 |
| Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants. | Investigative ophthalmology & visual science 20101201 |
| Optical fiber-coupled ocular spectrometer for measurement of drug concentration in the anterior eye--applications in pharmaceuticals research. | IEEE transactions on bio-medical engineering 20101201 |
| Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat. | The Journal of pharmacology and experimental therapeutics 20101201 |
| Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity. | Naunyn-Schmiedeberg's archives of pharmacology 20101201 |
| A comparative study on the efficacy, safety, and cost-effectiveness of bimatoprost/timolol and dorzolamide/timolol combinations in glaucoma patients. | Indian journal of pharmacology 20101201 |
| Diurnal and nocturnal effects of brimonidine monotherapy on intraocular pressure. | Ophthalmology 20101101 |
| Regional heterogeneity of α-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle. | The Journal of physiology 20101101 |
| Applications of nanoparticles in ophthalmology. | Progress in retinal and eye research 20101101 |
| α₂-Adrenoceptor functionality in postmortem frontal cortex of depressed suicide victims. | Biological psychiatry 20101101 |
| Bimatoprost 0.03% versus brimonidine 0.2% in the prevention of intraocular pressure spike following neodymium:yttrium–aluminum–garnet laser posterior capsulotomy. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20101001 |
| Effects of brimonidine 0.2%-timolol 0.5% fixed-combination therapy for glaucoma. | Japanese journal of ophthalmology 20100901 |
| A case of essential iris atrophy in a male patient. | Journal of the Indian Medical Association 20100901 |
| Nimodipine enhancement of alpha2 adrenergic modulation of NMDA receptor via a mechanism independent of Ca2+ channel blocking. | Investigative ophthalmology & visual science 20100801 |
| Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor. | Molecular pharmacology 20100801 |
| Similar effects of selective laser trabeculoplasty and prostaglandin analogs on the permeability of cultured Schlemm canal cells. | American journal of ophthalmology 20100801 |
| Brimonidine hypersensitivity when switching between 0.2% and 0.15% formulations. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20100801 |
| Short-term effect of topical brimonidine tartrate on intrastromal corneal pressure in rabbits. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20100701 |
| Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins. | Journal of applied physiology (Bethesda, Md. : 1985) 20100701 |
| Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol. | Current medical research and opinion 20100701 |
| Association for Research in Vision and Ophthalmology (ARVO)--2010 Annual Meeting. For Sight: The Future of Eye and Vision Research--part 2. | IDrugs : the investigational drugs journal 20100701 |
| Brimonidine and eye pressure. | Ophthalmology 20100701 |
| Matrix metalloproteinase-9 expression in retinal ganglion cell layer and effect of topically applied brimonidine tartrate 0.2% therapy on this expression in an endothelin-1-induced optic nerve ischemia model. | International ophthalmology 20100601 |
| The effect of brimonidine on transepithelial resistance in a human retinal pigment epithelial cell line. | Korean journal of ophthalmology : KJO 20100601 |
| Brimonidine for glaucoma. | Expert opinion on drug safety 20100501 |
| Pseudopheochromocytoma secondary to brimonidine ophthalmic solution. | The American journal of medicine 20100501 |
| Reaction of Müller cells in an experimental rat model of increased intraocular pressure following timolol, latanoprost and brimonidine. | Brain research bulletin 20100429 |
| Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned rats. | Brain research 20100409 |
| Microbial keratitis secondary to infection with Citrobacter koseri. | Cornea 20100401 |
| Fixed combinations of dorzolamide-timolol and brimonidine-timolol in the management of glaucoma. | Expert opinion on pharmacotherapy 20100401 |
| Use of rituximab for periocular and intraocular mucosa-associated lymphoid tissue lymphoma. | Ocular immunology and inflammation 20100401 |
| Effect of brimonidine/timolol fixed combination on preventing the short-term intraocular pressure increase after intravitreal injection of ranibizumab. | Klinische Monatsblatter fur Augenheilkunde 20100401 |
| Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells. | Cytometry. Part B, Clinical cytometry 20100301 |
| Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine. | Investigative ophthalmology & visual science 20100201 |
| Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells. | British journal of pharmacology 20100201 |
| Early flap dislocation with perioperative brimonidine use in laser in situ keratomileusis. | Journal of cataract and refractive surgery 20100201 |
| Intravitreal cysticercosis presenting as neovascular glaucoma. | Indian journal of ophthalmology 20100101 |
| Combination brimonidine and timolol. | Ophthalmology 20100101 |
| Brimonidine is neuroprotective against glutamate-induced neurotoxicity, oxidative stress, and hypoxia in purified rat retinal ganglion cells. | Molecular vision 20100101 |
| Considerations in glaucoma therapy: fixed combinations versus their component medications. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Recurrent vitreous occlusion of glaucoma drainage device tube in a patient with glaucoma in aphakia: a case report. | Cases journal 20100101 |
| Keratitis caused by the recently described new species Aspergillus brasiliensis: two case reports. | Journal of medical case reports 20100101 |
| Use of brimonidine before LASIK with femtosecond laser-created flaps for the correction of myopia: a contralateral eye study. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20100101 |
| Neutrophils compromise retinal pigment epithelial barrier integrity. | Journal of biomedicine & biotechnology 20100101 |
| Bilateral anterior ischemic optic neuropathy after bilateral neck dissection. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medications. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Patient persistence with first-line antiglaucomatous monotherapy. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Efficacy and safety of the pars plana clip in the Ahmed valve device inserted via the pars plana in patients with refractory glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Bimatoprost effects on aqueous humor dynamics in monkeys. | Journal of ophthalmology 20100101 |
| Misleading Goldmann applanation tonometry in a post-LASIK eye with interface fluid syndrome. | Indian journal of ophthalmology 20100101 |
| Efficacy of Garcinia kola 0.5% Aqueous Eye Drops in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension. | Middle East African journal of ophthalmology 20100101 |
| Efficacy of brimonidine in preventing intraocular pressure spikes following phacoemulsification in glaucoma patients. | European journal of ophthalmology 20100101 |
| Effect of intracameral injection of fibrin tissue sealant on the rabbit anterior segment. | Molecular vision 20100101 |
| Tolerability and effectiveness of preservative-free dorzolamide-timolol (preservative-free COSOPT) in patients with open-angle glaucoma or ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Management of bilateral idiopathic healed sclerokeratouveitis with ciliary and intercalary staphyloma with complicated cataract and secondary glaucoma. | Indian journal of ophthalmology 20100101 |
| Effect of travoprost on 24-hour intraocular pressure in normal tension glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Crystallization after intravitreal ganciclovir injection. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Efficacy and patient tolerability of travoprost BAK-free solution in patients with open-angle glaucoma and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| First-visit diagnosis of preperimetric glaucoma. | The open ophthalmology journal 20100101 |
| Sustained intraocular pressure elevation after intravitreal injection of bevacizumab and ranibizumab associated with trabeculitis. | The open ophthalmology journal 20100101 |
| Topiramate-associated bilateral anterior uveitis and angle closure glaucoma. | Indian journal of ophthalmology 20100101 |
| Fixed combination of bimatoprost and timolol in patients with primary open-angle glaucoma or ocular hypertension with inadequate IOP adjustment. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Prostaglandin-induced cystoid macular edema following routine cataract extraction. | Journal of ophthalmology 20100101 |
| Indirect comparisons: a review of reporting and methodological quality. | PloS one 20100101 |
| Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma. | Molecular vision 20100101 |
| The tear fluid mucin 5AC change of primary angle-closure glaucoma patients after short-term medications and phacotrabeculectomy. | Molecular vision 20100101 |
| A randomized, controlled comparison of macroscopic conjunctival hyperemia in patients treated with bimatoprost 0.01% or vehicle who were previously controlled on latanoprost. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Preparation and Evaluation of Nano-vesicles of Brimonidine Tartrate as an Ocular Drug Delivery System. | Journal of young pharmacists : JYP 20100101 |
| Updates in the treatment of ocular allergies. | Journal of asthma and allergy 20100101 |
| Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension. | Drug, healthcare and patient safety 20100101 |
| Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins. | Neurochemistry international 20091201 |
| Surveillance of glaucoma medical therapy in a Glasgow teaching hospital: 26 years' experience. | The British journal of ophthalmology 20091201 |
| A network meta-analysis combined direct and indirect comparisons between glaucoma drugs to rank effectiveness in lowering intraocular pressure. | Journal of clinical epidemiology 20091201 |
| Functional autoradiography and gene expression analysis applied to the characterization of the alpha2-adrenergic system in the chicken brain. | Journal of chemical neuroanatomy 20091201 |
| Retinal oxidative stress induced by intraocular hypertension in rats may be ameliorated by brimonidine treatment and N-acetyl cysteine supplementation. | Journal of glaucoma 20091201 |
| Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20091201 |
| From the bedside to the bench and back again: predicting and improving the outcomes of SLT glaucoma therapy. | Transactions of the American Ophthalmological Society 20091201 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Effectiveness of daily use of brimonidine as antimydriatic agent. | Journal of cataract and refractive surgery 20091001 |
| Ocular hypotensive effects of anti-glaucoma agents in mice. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20091001 |
| The effects of combination glaucoma medications on ocular surface epithelial cells. | Advances in therapy 20091001 |
| Analysis of alpha2-adrenergic receptors and effect of brimonidine on matrix metalloproteinases and their inhibitors in human ciliary body. | Investigative ophthalmology & visual science 20090901 |
| Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs. | Ophthalmology 20090901 |
| Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. | Clinical & experimental ophthalmology 20090901 |
| Intravitreal bevacizumab for the treatment of neovascular glaucoma associated with central retinal artery occlusion. | Korean journal of ophthalmology : KJO 20090901 |
| Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis. | Pharmacology & therapeutics 20090801 |
| Increased risk for flap dislocation with perioperative brimonidine use in femtosecond laser in situ keratomileusis. | Journal of cataract and refractive surgery 20090801 |
| A medical device/drug delivery system for treatment of glaucoma. | Clinical & experimental optometry 20090701 |
| Meta-analysis of medical intervention for normal tension glaucoma. | Ophthalmology 20090701 |
| Safety and tolerability of brimonidine purite 0.1% and brimonidine purite 0.15%: a meta-analysis of two phase 3 studies. | Current medical research and opinion 20090701 |
| Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy. | Current medical research and opinion 20090701 |
| Spontaneous anterior lens capsular dehiscence causing lens particle glaucoma. | Yonsei medical journal 20090630 |
| Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603 |
| Intravitreal bevacizumab (Avastin) treatment of neovascular glaucoma in ocular ischemic syndrome. | Korean journal of ophthalmology : KJO 20090601 |
| Differential involvement of alpha1-adrenoceptors in vasoconstrictor responses to cooling in mouse plantar arteries in vitro and in vivo. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090601 |
| Changes in visual function after intraocular pressure reduction using antiglaucoma medications. | Eye (London, England) 20090501 |
| Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis. | Clinical and experimental immunology 20090501 |
| Noradrenergic control of associative synaptic plasticity by selective modulation of instructive signals. | Neuron 20090416 |
| Treatment of patients with primary open-angle glaucoma with a fixed combination of brimonidine 0.2%/timolol 0.5%: multicenter, open-label, observational study in Germany. | Current medical research and opinion 20090401 |
| Experimental and clinical evidence for brimonidine as an optic nerve and retinal neuroprotective agent: an evidence-based review. | Archives of ophthalmology (Chicago, Ill. : 1960) 20090401 |
| [Development of conjunctival hyperemia with the use of a fixed combination of latanoprost/timolol: systematic review and meta-analysis of clinical trials]. | Archivos de la Sociedad Espanola de Oftalmologia 20090401 |
| Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20090401 |
| Inherited mitochondrial optic neuropathies. | Journal of medical genetics 20090301 |
| Temporal evolution of intraocular pressure elevation after pupillary dilation in pigment dispersion syndrome. | Journal of glaucoma 20090301 |
| Intravitreal triamcinolone acetonide injection at the time of pars plana vitrectomy for retained lens material. | Korean journal of ophthalmology : KJO 20090301 |
| Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships. | Journal of medicinal chemistry 20090212 |
| Effect of brimonidine on retinal ganglion cell survival in an optic nerve crush model. | American journal of ophthalmology 20090201 |
| Brimonidine tartrate poisoning in children: frequency, trends, and use of naloxone as an antidote. | Pediatrics 20090201 |
| Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia. | Anesthesiology 20090201 |
| A rapid and sensitive LC/MS/MS assay for the quantitation of brimonidine in ocular fluids and tissues. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115 |
| Aceclidine, brimonidine tartrate, and dapiprazole: comparison of miotic effect and tolerability under different lighting conditions. | Journal of cataract and refractive surgery 20090101 |
| Pediatric systemic poisoning resulting from brimonidine ophthalmic drops. | Pediatric emergency care 20090101 |
| Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: a case report. | Journal of medical case reports 20090101 |
| Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature. | Nutrition & metabolism 20090101 |
| Challenging issues in molecular-targeted therapy. | Therapeutics and clinical risk management 20090101 |
| Exposure to topical apraclonidine in children with glaucoma. | Journal of glaucoma 20090101 |
| Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost. | Ophthalmic research 20090101 |
| Ophthalmologist attitudes regarding fixed combination treatment for glaucoma in the European Union. | European journal of ophthalmology 20090101 |
| Cardiorespiratory depression and hyperglycemia after unintentional ingestion of brimonidine in a neonate. | European journal of ophthalmology 20090101 |
| Current concepts in the pathophysiology of glaucoma. | Indian journal of ophthalmology 20090101 |
| Bilateral granulomatous uveitis as a side effect of topical brimonidine: two case reports. | Bulletin de la Societe belge d'ophtalmologie 20090101 |
| Alpha2 adrenoceptors modulate histamine release from sympathetic nerves in the guinea pig vas deferens. | Neuropharmacology 20090101 |
| cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake. | Molecular brain 20090101 |
| Intravitreal injection of tissue plasminogen activator as treatment for an occluded pars plana glaucoma tube. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| A comfort comparison of travoprost BAK-free 0.004% versus latanoprost 0.005% in patients with primary open-angle glaucoma or ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Preliminary results following the use of a fixed combination of timolol-brimonidine in patients with ocular hypertension and primary open-angle glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Intracameral dexamethasone reduces inflammation on the first postoperative day after cataract surgery in eyes with and without glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Aerobic exercise and intraocular pressure in normotensive and glaucoma patients. | BMC ophthalmology 20090101 |
| Efficacy and safety of prostaglandin analogues in patients with predominantly primary open-angle glaucoma or ocular hypertension: a meta-analysis. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Effects of brinzolamide vs timolol as an adjunctive medication to latanoprost on circadian intraocular pressure control in primary open-angle glaucoma Japanese patients. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Study of the effects of ocular hypotensive drugs on number of neurons in the retinal ganglion layer in a rat experimental glaucoma. | European journal of ophthalmology 20090101 |
| Intracameral recombinant tissue plasminogen activator for refractory glaucoma secondary to a fungal corneal abscess. | The open ophthalmology journal 20090101 |
| Extensive facial skin pigmentation after latanoprost treatment. | Cutaneous and ocular toxicology 20090101 |
| Astrocyte and microglial activation in the lateral geniculate nucleus and visual cortex of glaucomatous and optic nerve transected primates. | Molecular vision 20090101 |
| Short and long term axotomy-induced ERG changes in albino and pigmented rats. | Molecular vision 20090101 |
| First-year treatment costs among new initiators of topical prostaglandin analogs. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice. | Molecular vision 20090101 |
| Immunohistochemical changes in rat retinas at various time periods of elevated intraocular pressure. | Molecular vision 20090101 |
| Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| The efficacy and safety of two fixed combinations: timolol-dorzolamide-brimonidine versus timolol-dorzolamide. A prospective, randomized, double-masked, multi-center, 6-month clinical trial. | Annals of ophthalmology (Skokie, Ill.) 20090101 |
| An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/dorzolamide 2% in patients with elevated intraocular pressure. | Journal of glaucoma 20081201 |
| Pericardium plug in the repair of the corneoscleral fistula after Ahmed Glaucoma Valve explantation. | Korean journal of ophthalmology : KJO 20081201 |
| Latanoprost ophthalmic solution in the treatment of open angle glaucoma or raised intraocular pressure: a review. | Clinical ophthalmology (Auckland, N.Z.) 20081201 |
| The trabecular bypass stent in a pseudophakic glaucoma patient: A 1-year follow-up. | Clinical ophthalmology (Auckland, N.Z.) 20081201 |
| Twenty-four-hour efficacy of the brimonidine/timolol fixed combination versus therapy with the unfixed components. | Eye (London, England) 20081101 |
| Efficacy, safety, and current applications of brimonidine. | Expert opinion on drug safety 20081101 |
| Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity. | Investigative ophthalmology & visual science 20081001 |
| Adrenergic regulation of cAMP/protein kinase A pathway in corneal epithelium and endothelium. | Ophthalmic research 20081001 |
| Recent advances in pharmacotherapy of glaucoma. | Indian journal of pharmacology 20081001 |
| Miscellaneous. | Indian journal of pharmacology 20081001 |
| Comparison of allergy rates in glaucoma patients receiving brimonidine 0.2% monotherapy versus fixed-combination brimonidine 0.2%-timolol 0.5% therapy. | Current medical research and opinion 20080901 |
| Effect of brimonidine tartrate 0.15% on night-vision difficulty and contrast testing after refractive surgery. | Journal of cataract and refractive surgery 20080901 |
| Neodymium YAG laser and surgical synechiolysis of iridocapsular adhesions. | Korean journal of ophthalmology : KJO 20080901 |
| Clinical Ophthalmology and PubMed. | Clinical ophthalmology (Auckland, N.Z.) 20080901 |
| Brinzolamide ophthalmic suspension: a review of its pharmacology and use in the treatment of open angle glaucoma and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20080901 |
| Fixed combination of topical brimonidine 0.2% and timolol 0.5% for glaucoma and uncontrolled intraocular pressure. | Clinical ophthalmology (Auckland, N.Z.) 20080901 |
| Oxidative stress plays a permissive role in alpha2-adrenoceptor-mediated events in immortalized SHR proximal tubular epithelial cells. | Molecular and cellular biochemistry 20080801 |
| Effects of advanced glycation end products-inductor glyoxal and hydrogen peroxide as oxidative stress factors on rat retinal organ cultures and neuroprotection by UK-14,304. | Journal of neurochemistry 20080801 |
| [Brimonidine intoxication in paediatrics. A presentation as intracranial hypertension syndrome]. | Anales de pediatria (Barcelona, Spain : 2003) 20080801 |
| Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines. | Ophthalmology 20080701 |
| Noradrenergic and GABA B receptor activation differentially modulate inputs to the premotor nucleus RA in zebra finches. | Journal of neurophysiology 20080701 |
| Partial agonism at the human alpha(2A)-autoreceptor: role of binding duration. | Naunyn-Schmiedeberg's archives of pharmacology 20080701 |
| Brimonidine-purite 0.1% versus brimonidine-purite 0.15% twice daily in glaucoma or ocular hypertension: a 12-month randomized trial. | Current medical research and opinion 20080701 |
| Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants. | Journal of medicinal chemistry 20080612 |
| Letter to the editor regarding Gerente, V.M., Biondi, A.C., Barbosa, C.P., et al. Effect of brimonidine tartrate 0.15% on scotopic pupil: controlled trial. J. Ocul. Pharmacol. Ther 23:476-480, 2007. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080601 |
| Efficacy of brimonidine tartrate 0.2% ophthalmic solution in reducing halos after laser in situ keratomileusis. | Journal of cataract and refractive surgery 20080601 |
| Pharmacological characterization of alpha2D-adrenergic receptor-mediated [35S]GTPgammaS binding in rat cerebral cortical membranes. | Pharmacological research 20080601 |
| Neurodegenerative diseases of the retina and potential for protection and recovery. | Current neuropharmacology 20080601 |
| Intravitreal triamcinolone acetonide: Pattern of secondary intraocular pressure rise and possible risk factors. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Efficacy and tolerability of a large scale change in regimen from latanoprost to travoprost in glaucoma patients at the Manhattan Veterans Administration Hospital. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| A study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to latanoprost 0.005% and timolol 0.5% dosed concomitantly in patients with open-angle glaucoma or ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Rational use of the fixed combination of dorzolamide - timolol in the management of raised intraocular pressure and glaucoma. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Inhibition of opioid release in the rat spinal cord by alpha2C adrenergic receptors. | Neuropharmacology 20080501 |
| Retinal ganglion cell neuroprotection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments. | Experimental eye research 20080501 |
| Brimonidine purite 0.1% versus brinzolamide 1% as adjunctive therapy to latanoprost in patients with glaucoma or ocular hypertension. | Current medical research and opinion 20080501 |
| Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080401 |
| Meta-analysis of randomized controlled trials comparing timolol with brimonidine in the treatment of glaucoma. | Clinical & experimental ophthalmology 20080401 |
| Alpha 2A-adrenoceptor-specific stimulation of [35S]GTP gamma S binding to membrane preparations of rat frontal cortex. | Neurochemical research 20080301 |
| ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. | British journal of pharmacology 20080301 |
| Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. | Hypertension (Dallas, Tex. : 1979) 20080301 |
| Normal-tension glaucoma. | Ophthalmology 20080301 |
| Effects of central corneal thickness on the efficacy of topical ocular hypotensive medications. | Journal of glaucoma 20080301 |
| Central alpha-2 adrenergic eye drops: case series of 3 pediatric systemic poisonings. | Pediatric emergency care 20080301 |
| Managing refractory glaucoma with a fixed combination of bimatoprost (0.03%) and timolol (0.5%). | Clinical ophthalmology (Auckland, N.Z.) 20080301 |
| Noradrenergic vasoconstriction of pig prostatic small arteries. | Naunyn-Schmiedeberg's archives of pharmacology 20080201 |
| A pilot study of topical treatment with an alpha2-agonist in patients with retinal dystrophies. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080201 |
| Prostaglandin analogues for ophthalmic use: a cost-effectiveness analysis. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20080201 |
| New drug information. Combigan. | JAAPA : official journal of the American Academy of Physician Assistants 20080201 |
| Cost analysis of glaucoma medications. | American journal of ophthalmology 20080101 |
| The efficacy and harm of prostaglandin analogues for IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review. | The British journal of ophthalmology 20080101 |
| Drug modification of angiogenesis in a rat cornea model. | Investigative ophthalmology & visual science 20080101 |
| Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery. | Eye & contact lens 20080101 |
| Acute bilateral simultaneous angle closure glaucoma after topiramate administration: a case report. | Journal of medical case reports 20080101 |
| Reversible cicatricial ectropion precipitated by topical brimonidine eye drops. | Ophthalmic plastic and reconstructive surgery 20080101 |
| Brimonidine-induced anterior uveitis and conjunctivitis: clinical and histologic features. | Journal of glaucoma 20080101 |
| Good functional recovery following intervention for delayed suprachoroidal haemorrhage post bleb needling: a case report. | Journal of medical case reports 20080101 |
| Transconjunctival penetration of mitomycin C. | Indian journal of ophthalmology 20080101 |
| Practical approach to medical management of glaucoma. | Indian journal of ophthalmology 20080101 |
| Post-penetrating keratoplasty glaucoma. | Indian journal of ophthalmology 20080101 |
| Corneal edema following diode laser cyclophotocoagulation in an eye with secondary glaucoma. | Indian journal of ophthalmology 20080101 |
| Plasminogen activator inhibitor-1 4G/5G gene polymorphism and primary open-angle glaucoma. | Molecular vision 20080101 |
| Yohimbine-induced alterations in alpha(2)-adrenoceptors in kidney regions of the spontaneously hypertensive rats: an autoradiographic analysis. | Pharmacological reports : PR 20080101 |
| Apoptosis in the trabecular meshwork of glaucomatous patients. | Molecular vision 20080101 |
| Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration. | BMC pharmacology 20080101 |
| A European perspective on costs and cost effectiveness of ophthalmic combinations in the treatment of open-angle glaucoma. | European journal of ophthalmology 20080101 |
| Absorption of brimonidine 0.1% and 0.15% ophthalmic solutions in the aqueous humor of cataract patients. | Journal of glaucoma 20080101 |
| Ocular parasitosis: a rare cause of hypertensive uveitis. | Indian journal of ophthalmology 20080101 |
| [Efficacy of topic ocular hipotensive agents after posterior capsulotomy]. | Arquivos brasileiros de oftalmologia 20080101 |
| Reporting of noninferiority and equivalence randomized trials for major prostaglandins: a systematic survey of the ophthalmology literature. | Trials 20080101 |
| Glaucoma alters the circadian timing system. | PloS one 20080101 |
| Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON). | Molecular vision 20080101 |
| [Fixed combinations of glaucoma medications]. | Oftalmologia (Bucharest, Romania : 1990) 20080101 |
| Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database. | Journal of medical economics 20080101 |
| Medical management of primary open-angle glaucoma: Best practices associated with enhanced patient compliance and persistency. | Patient preference and adherence 20080101 |
| Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension. | Current medical research and opinion 20071201 |
| Cystoid macular edema in a pseudophakic patient after switching from latanoprost to BAK-free travoprost. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071201 |
| Noradrenergic control of odor recognition in a nonassociative olfactory learning task in the mouse. | Learning & memory (Cold Spring Harbor, N.Y.) 20071201 |
| EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing. | European journal of pharmacology 20071128 |
| Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner. | Journal of neurochemistry 20071101 |
| Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat. | Journal of cataract and refractive surgery 20071101 |
| Medical interventions for primary open angle glaucoma and ocular hypertension. | The Cochrane database of systematic reviews 20071017 |
| The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats. | American journal of physiology. Cell physiology 20071001 |
| Brimonidine 0.2% versus brimonidine Purite 0.15% in Asian ocular hypertension. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071001 |
| Effect of brimonidine tartrate 0.15% on scotopic pupil: controlled trial. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071001 |
| The use of dorzolamide versus other hypotensive agents to prevent glaucomatous progression. | Therapeutics and clinical risk management 20071001 |
| Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers. | Journal of medicinal chemistry 20070906 |
| Effects of topical clonidine versus brimonidine on choroidal blood flow and intraocular pressure during squatting. | Investigative ophthalmology & visual science 20070901 |
| Effect of prophylactic brimonidine instillation on bleeding during strabismus surgery in adults. | American journal of ophthalmology 20070901 |
| Unintentional ingestion of brimonidine antiglaucoma drops: a case report and review of the literature. | Pediatric emergency care 20070901 |
| Intravitreal bevacizumab: an analysis of the evidence. | Clinical ophthalmology (Auckland, N.Z.) 20070901 |
| Cooling augments vasoconstriction mediated by 5-HT1 and alpha2-adrenoceptors in the isolated equine digital vein: involvement of Rho kinase. | European journal of pharmacology 20070827 |
| Neuroprotective effect of topically applied brimonidine tartrate 0.2% in endothelin-1-induced optic nerve ischaemia model. | Clinical & experimental ophthalmology 20070801 |
| Ocular comfort of combination glaucoma therapies: brimonidine 0.2%/timolol 0.5% compared with dorzolamide 2%/timolol 0.5%. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070801 |
| Brimonidine for anisocoria. | Ophthalmology 20070701 |
| Comparison of the ocular hypotensive efficacy of adjunctive brimonidine 0.15% or brinzolamide 1% in combination with travoprost 0.004%. | Ophthalmology 20070701 |
| [Depression of respiration via toxic effects on the central nervous system following use of topical brimonidine in an infant with congenital glaucoma]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20070601 |
| Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. | Molecular pharmacology 20070601 |
| Special considerations in low-tension glaucoma. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070601 |
| Bilateral spontaneous anterior lens dislocation in a retinitis pigmentosa patient. | Korean journal of ophthalmology : KJO 20070601 |
| Expression of adrenergic receptors in mouse preimplantation embryos and ovulated oocytes. | Reproduction (Cambridge, England) 20070601 |
| Presynaptic modulation of 5-HT release in the rat septal region. | Neuroscience 20070511 |
| Presynaptic alpha-adrenoceptors in median preoptic nucleus modulate inhibitory neurotransmission from subfornical organ and organum vasculosum lamina terminalis. | American journal of physiology. Regulatory, integrative and comparative physiology 20070501 |
| Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins. | British journal of pharmacology 20070501 |
| Reduced ocular allergy with fixed-combination 0.2% brimonidine-0.5% timolol. | Archives of ophthalmology (Chicago, Ill. : 1960) 20070501 |
| Fixed-combination and emerging glaucoma therapies. | Expert opinion on emerging drugs 20070501 |
| Effects of brimonidine ingestion on cardiovascular responses and renal function in conscious dogs. | Veterinary research communications 20070401 |
| Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure. | Current medical research and opinion 20070401 |
| Visual field and intraocular pressure asymmetry in the low-pressure glaucoma treatment study. | Ophthalmology 20070301 |
| Cathine, an amphetamine-related compound, acts on mammalian spermatozoa via beta1- and alpha2A-adrenergic receptors in a capacitation state-dependent manner. | Human reproduction (Oxford, England) 20070301 |
| Alpha2 adrenergic receptor-mediated modulation of cytosolic Ca++ signals at the inner plexiform layer of the rat retina. | Investigative ophthalmology & visual science 20070301 |
| Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells. | The Kaohsiung journal of medical sciences 20070301 |
| Travoprost in the management of open-angle glaucoma and ocular hypertension. | Clinical ophthalmology (Auckland, N.Z.) 20070301 |
| Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse. | Neuroscience 20070209 |
| Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release. | Neuropharmacology 20070201 |
| Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy. | Experimental eye research 20070201 |
| Drug-induced ectropion: what is best practice? | Ophthalmology 20070201 |
| Characterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine in vitro and in rats in vivo using on-line HID exchange LC-MS/MS and stable-isotope tracer techniques. | Xenobiotica; the fate of foreign compounds in biological systems 20070201 |
| Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs. | The British journal of ophthalmology 20070101 |
| Meta-analysis of randomised controlled trials comparing latanoprost with brimonidine in the treatment of open-angle glaucoma, ocular hypertension or normal-tension glaucoma. | The British journal of ophthalmology 20070101 |
| Grand rounds: could occupational exposure to n-hexane and other solvents precipitate visual failure in leber hereditary optic neuropathy? | Environmental health perspectives 20070101 |
| Pharmacologic management of glaucoma in childhood. | Paediatric drugs 20070101 |
| Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro. | Molecular vision 20070101 |
| Ocular hypotensive efficacy of brimonidine 0.15% as adjunctive therapy with latanoprost 0.005% in patients with open-angle glaucoma or ocular hypertension. | Advances in therapy 20070101 |
| Unilateral dysphotopsia after bilateral intraocular lens implantation using the AR40e IOL model: case report. | Arquivos brasileiros de oftalmologia 20070101 |
| Alteration of retinal intrinsic survival signal and effect of alpha2-adrenergic receptor agonist in the retina of the chronic ocular hypertension rat. | Visual neuroscience 20070101 |
| Changes in medical and surgical treatments of glaucoma between 1997 and 2003 in France. | European journal of ophthalmology 20070101 |
| Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line. | BMC neuroscience 20070101 |
| Interpretation of uniocular and binocular trials of glaucoma medications: an observational case series. | BMC ophthalmology 20070101 |
| Estrogen is not neuroprotective in a rodent model of optic nerve stroke. | Molecular vision 20070101 |
| Daily cost of glaucoma medications in China. | Journal of glaucoma 20070101 |
| The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment. | BMC pharmacology 20070101 |
| [Neuroprotection in glaucoma]. | Annales Academiae Medicae Stetinensis 20070101 |
| Functional interaction between alpha2-adrenoceptors, mu- and kappa-opioid receptors in the guinea pig myenteric plexus: effect of chronic desipramine treatment. | European journal of pharmacology 20061228 |
| The growth factor response in ischemic rat retina and superior colliculus after brimonidine pre-treatment. | Brain research bulletin 20061211 |
| Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta. | British journal of pharmacology 20061201 |
| Non-systemic delivery of topical brimonidine to the brain: a neuro-ocular tissue distribution study. | Journal of drug targeting 20061201 |
| Editorial foreword. | Therapeutics and clinical risk management 20061201 |
| Brimonidine in the treatment of glaucoma and ocular hypertension. | Therapeutics and clinical risk management 20061201 |
| Effect of Proview self-tonometry on pharmaceutical compliance. | Clinical & experimental optometry 20061101 |
| Enaminones and norepinephrine employ convergent mechanisms to depress excitatory synaptic transmission in the rat nucleus accumbens in vitro. | The European journal of neuroscience 20061101 |
| Allergic contact dermatitis caused by topical eye drops. | American journal of ophthalmology 20061001 |
| Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors. | The Journal of pharmacology and experimental therapeutics 20060901 |
| Successful management of orbital cellulitis and temporary visual loss after blepharoplasty. | Plastic and reconstructive surgery 20060901 |
| Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial. | Archives of ophthalmology (Chicago, Ill. : 1960) 20060901 |
| Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors. | Fundamental & clinical pharmacology 20060801 |
| The safety and intraocular pressure-lowering efficacy of brimonidine tartrate 0.15% preserved with polyquaternium-1. | Ophthalmology 20060801 |
| Vitreous concentration of topically applied brimonidine-purite 0.15%. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060801 |
| Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts. | European journal of pharmacology 20060710 |
| Brimonidine evokes heterogeneous vasomotor response of retinal arterioles: diminished nitric oxide-mediated vasodilation when size goes small. | American journal of physiology. Heart and circulatory physiology 20060701 |
| Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma. | Investigative ophthalmology & visual science 20060701 |
| K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil. | Neuroscience research 20060601 |
| Progression of visual field defects in leber hereditary optic neuropathy: experience of the LHON treatment trial. | American journal of ophthalmology 20060601 |
| A rat model for acute rise in intraocular pressure: immune modulation as a therapeutic strategy. | American journal of ophthalmology 20060601 |
| An evaluation of the rate of nonresponders to latanoprost therapy. | Journal of glaucoma 20060601 |
| Is brimonidine ophthalmic a safe therapy for infants? | Journal of clinical pharmacy and therapeutics 20060601 |
| Brimonidine 0.2% versus brimonidine Purite 0.15%: prophylactic effect on iop elevation after Nd:YAG laser posterior capsulotomy. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060601 |
| Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macular edema and posterior subtenon injection for uveitis. | Korean journal of ophthalmology : KJO 20060601 |
| The management of glaucoma and intraocular hypertension: current approaches and recent advances. | Therapeutics and clinical risk management 20060601 |
| Efficacy and tolerability of 0.2% brimonidine tartrate for the treatment of acute non-arteritic anterior ischemic optic neuropathy (NAION): a 3-month, double-masked, randomised, placebo-controlled trial. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Acute vibration increases alpha2C-adrenergic smooth muscle constriction and alters thermosensitivity of cutaneous arteries. | Journal of applied physiology (Bethesda, Md. : 1985) 20060401 |
| Severe photic phenomenon. | Journal of cataract and refractive surgery 20060401 |
| Comparative analysis of the effects of brimonidine and dorzolamide on ocular blood flow velocity in patients with newly diagnosed primary open-angle glaucoma. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060401 |
| A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension. | Clinical therapeutics 20060401 |
| Effects of a topical alpha2 adrenergic agonist on ciliary blood flow and aqueous production in rabbits. | Experimental eye research 20060301 |
| Acute and long-term administration of citalopram desensitizes alpha2-adrenoceptors in the rat vas deferens. | The Journal of pharmacy and pharmacology 20060301 |
| [Ocular hypertension in children treated with brimonidine 0.2%. A clinical study]. | Archivos de la Sociedad Espanola de Oftalmologia 20060301 |
| Argon laser trabeculoplasty and reduction of ocular hypotensive medication used by glaucoma patients. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20060201 |
| Impairment of presynaptic alpha2-adrenoceptor-regulated norepinephrine overflow in failing hearts from Zucker diabetic fatty rats. | Journal of cardiovascular pharmacology 20060201 |
| Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells. | The Kaohsiung journal of medical sciences 20060201 |
| Characterization of brimonidine transport in retinal pigment epithelium. | Investigative ophthalmology & visual science 20060101 |
| Insertion of a foldable hydrophobic IOL through the trabeculectomy fistula in cases with microincision cataract surgery combined with trabeculectomy. | BMC ophthalmology 20060101 |
| Bilateral acute angle closure glaucoma as a presentation of isolated microspherophakia in an adult: case report. | BMC ophthalmology 20060101 |
| [Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20060101 |
| [Use of antiglaucoma therapy to reduce acute intraocular pressure rise following neodymium: YAG laser iridotomy in angle-closure glaucoma patients]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20060101 |
| Topical brimonidine 0.2%/timolol 0.5% ophthalmic solution: in glaucoma and ocular hypertension. | Drugs & aging 20060101 |
| Brimonidine/Timolol: a viewpoint by Richard Fiscella. | Drugs & aging 20060101 |
| Brimonidine/Timolol: a viewpoint by Robert M. Feldman. | Drugs & aging 20060101 |
| Brimonidine/Timolol: a viewpoint by Francisco J. Goñi. | Drugs & aging 20060101 |
| Imidazoline receptors in relaxation of acetylcholine-constricted isolated rat jejunum. | Pharmacological reports : PR 20060101 |
| Side-effect profile of brimonidine tartrate in children. | Ophthalmology 20051201 |
| Comparison of the effects of brimonidine 0.2% and timolol 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: a prospective, unmasked study. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20051201 |
| The effects of anesthetics and ethanol on alpha2 adrenoceptor subtypes expressed with G protein-coupled inwardly rectifying potassium channels in Xenopus oocytes. | Anesthesia and analgesia 20051101 |
| [Late endophthalmitis following Ahmed valve]. | Archivos de la Sociedad Espanola de Oftalmologia 20051101 |
| Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling. | Cellular signalling 20051001 |
| Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine. | Investigative ophthalmology & visual science 20051001 |
| [The effect of brimonidine on the pupillary reflex. A pupillographic study in healthy volunteers]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20050901 |
| Topical brimonidine reduces collateral damage caused by laser photocoagulation for choroidal neovascularization. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050901 |
| Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction. | The Journal of pharmacology and experimental therapeutics 20050901 |
| Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite. | American journal of ophthalmology 20050901 |
| Minimally invasive, direct, real time measurement of drug concentration in the anterior eye. | The British journal of ophthalmology 20050901 |
| Effect of brimonidine on pupil diameter. | Journal of cataract and refractive surgery 20050901 |
| Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery. | Journal of cataract and refractive surgery 20050901 |
| Two 'knockout' mouse models demonstrate that aortic vasodilatation is mediated via alpha2a-adrenoceptors located on the endothelium. | The Journal of pharmacology and experimental therapeutics 20050801 |
| Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor. | Journal of molecular endocrinology 20050801 |
| Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050801 |
| Oxytocin increases the density of high affinity alpha(2)-adrenoceptors within the hypothalamus, the amygdala and the nucleus of the solitary tract in ovariectomized rats. | Brain research 20050712 |
| alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons. | European journal of pharmacology 20050704 |
| Bilateral retinal venous occlusion in pigmentary glaucoma. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050701 |
| Influence of the membrane lipid structure on signal processing via G protein-coupled receptors. | Molecular pharmacology 20050701 |
| Intraocular pressure-lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials. | Ophthalmology 20050701 |
| Brimonidine versus dapiprazole: Influence on pupil size at various illumination levels. | Journal of cataract and refractive surgery 20050701 |
| Cost considerations of the new fixed combinations for glaucoma medical therapy. | Journal of clinical pharmacy and therapeutics 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Water-drinking test in patients with primary open-angle glaucoma while treated with different topical medications. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050601 |
| Prospective survey of adverse reactions to topical antiglaucoma medications in a hospital population. | Eye (London, England) 20050401 |
| Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors. | The Journal of pharmacology and experimental therapeutics 20050401 |
| Involvement of G i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC-12 cells and cortical neurons. | Molecular pharmacology 20050401 |
| The effect of combination pharmacotherapy on the prescription trends of glaucoma medications. | Journal of glaucoma 20050401 |
| Latanoprost or brimonidine as treatment for elevated intraocular pressure: multicenter trial in the United States. | Journal of glaucoma 20050401 |
| 24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects. | Ophthalmology 20050401 |
| Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor. | Journal of neuroscience research 20050315 |
| An unusual appearance of limbal conjunctival follicles in a patient on brimonidine and dorzolamide. | Eye (London, England) 20050301 |
| The Low-pressure Glaucoma Treatment Study (LoGTS) study design and baseline characteristics of enrolled patients. | Ophthalmology 20050301 |
| [Drug induced uveitis]. | Archivos de la Sociedad Espanola de Oftalmologia 20050301 |
| Comparison of additional intraocular pressure-lowering effects of latanoprost vs brimonidine in primary open-angle glaucoma patients with intraocular pressure uncontrolled by timolol-dorzolamide combination. | Eye (London, England) 20050201 |
| Alphagan allergy may increase the propensity for multiple eye-drop allergy. | Eye (London, England) 20050201 |
| Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050201 |
| Brimonidine 0.2% vs unoprostone 0.15% both added to timolol maleate 0.5% given twice daily to patients with primary open-angle glaucoma or ocular hypertension. | Eye (London, England) 20050101 |
| Heterologous desensitization of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Galphai2 and investigations on the mechanism involved. | Cell biochemistry and function 20050101 |
| Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428]. | BMC ophthalmology 20050101 |
| Effect of prophylactic brimonidine on bleeding complications after cataract surgery. | European journal of ophthalmology 20050101 |
| Comparing brimonidine 0.2% to apraclonidine 1.0% in the prevention of intraocular pressure elevation and their pupillary effects following laser peripheral iridotomy. | Japanese journal of ophthalmology 20050101 |
| An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission. | Neuroscience 20050101 |
| 12-week study comparing the fixed combination of brimonidine and timolol with concomitant use of the individual components in patients with glaucoma and ocular hypertension. | European journal of ophthalmology 20050101 |
| Differential gene expression in anatomical compartments of the human eye. | Genome biology 20050101 |
| [Contemporary possibilities and perspectives in the treatment of glaucoma]. | Annales Academiae Medicae Stetinensis 20050101 |
| [Anterior uveitis and topical brimonidine: a case report]. | Journal francais d'ophtalmologie 20041201 |
| Intravitreal triamcinolone injection for diabetic macular edema: a clinical and fluorescein angiographic case series. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20041201 |
| Polycarboxylic acid nanoparticles for ophthalmic drug delivery: an ex vivo evaluation with human cornea. | Journal of microencapsulation 20041201 |
| The efficacy of topical administration of brimonidine to reduce ischaemia in the very early stage of diabetic retinopathy in good controlled type-2 diabetes mellitus. | Journal of the Indian Medical Association 20041201 |
| Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice. | Neuroscience letters 20041103 |
| The role of Rho kinase and extracellular regulated kinase-mitogen-activated protein kinase in alpha2-adrenoceptor-mediated vasoconstriction in the porcine palmar lateral vein. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Efficacy and safety of the latanoprost/timolol maleate fixed combination vs concomitant brimonidine and latanoprost therapy. | Eye (London, England) 20041001 |
| Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels. | European journal of pharmacology 20040913 |
| Loss of endothelial KATP channel-dependent, NO-mediated dilation of endocardial resistance coronary arteries in pigs with left ventricular hypertrophy. | British journal of pharmacology 20040901 |
| Chronic morphine treatment reduces recovery from opioid desensitization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901 |
| Diurnal intraocular pressure and blood pressure with two dosing regimens of brimonidine in normal tension glaucoma. | Journal of the Chinese Medical Association : JCMA 20040901 |
| Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation. | Biochemical and biophysical research communications 20040813 |
| [Cost-effectivity analysis of the most used antiglaucoma drugs]. | Archivos de la Sociedad Espanola de Oftalmologia 20040801 |
| Miotic effect of brimonidine tartrate 0.15% ophthalmic solution in normal eyes. | Journal of cataract and refractive surgery 20040801 |
| Effect of brimonidine tartrate 0.2% ophthalmic solution on pupil size. | Journal of cataract and refractive surgery 20040801 |
| Effect of topical brinzolamide 1% and brimonidine 0.2% on intraocular pressure after phacoemulsification. | Journal of cataract and refractive surgery 20040801 |
| Effects of the preservative purite on the bioavailability of brimonidine in the aqueous humor of rabbits. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040801 |
| The comparative cardiovascular, pulmonary, ocular blood flow, and ocular hypotensive effects of topical travoprost, bimatoprost, brimonidine, and betaxolol. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040801 |
| [Neuroprotection and regeneration after traumatic lesion of the optic nerve]. | Klinische Monatsblatter fur Augenheilkunde 20040801 |
| alpha2-Adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons. | Brain research 20040716 |
| A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe. | The British journal of ophthalmology 20040701 |
| Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension. | The British journal of ophthalmology 20040701 |
| The effect of daily use of brimonidine tartrate on the dark-adapted pupil diameter. | American journal of ophthalmology 20040701 |
| Anterior uveitis and concurrent allergic conjunctivitis associated with long-term use of topical 0.2% brimonidine tartrate. | Archives of ophthalmology (Chicago, Ill. : 1960) 20040701 |
| Trends in glaucoma surgery before and after the introduction of new topical glaucoma pharmacotherapies. | Journal of glaucoma 20040601 |
| Inhibition of endothelin-1 and KCL-induced increase of [CA2+]i by antiglaucoma drugs in cultured A7r5 vascular smooth-muscle cells. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040601 |
| Comparative study of the effects of desipramine and reboxetine on locus coeruleus neurons in rat brain slices. | Neuropharmacology 20040501 |
| Charles Bonnet syndrome and brimonidine: comments. | The British journal of ophthalmology 20040501 |
| Adrenoceptor agonist poisoning after accidental oral ingestion of brimonidine eye drops. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20040501 |
| Increased tyrosine phosphorylation mediates the cooling-induced contraction and increased vascular reactivity of Raynaud's disease. | Arthritis and rheumatism 20040501 |
| Glaucoma management in developing countries: medical, laser, and surgical options for glaucoma management in countries with limited resources. | Current opinion in ophthalmology 20040401 |
| Fixed combinations of topical glaucoma medications. | Current opinion in ophthalmology 20040401 |
| Management of inflammatory glaucomas. | Current opinion in ophthalmology 20040401 |
| Tonopen measurement of intraocular pressure in mice. | Experimental eye research 20040401 |
| The safety and efficacy of unoprostone 0.15% versus brimonidine 0.2%. | Acta ophthalmologica Scandinavica 20040401 |
| Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures. | Journal of glaucoma 20040401 |
| Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy. | Journal of glaucoma 20040401 |
| Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension. | Journal of glaucoma 20040401 |
| [Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers]. | Archivos de la Sociedad Espanola de Oftalmologia 20040401 |
| Noradrenaline inhibits autonomous activity in the isolated guinea pig bladder. | BJU international 20040201 |
| Aqueous humor flow in normal human eyes treated with brimonidine and dorzolamide, alone and in combination. | Archives of ophthalmology (Chicago, Ill. : 1960) 20040201 |
| Brimonidine and latanoprost as adjunctive therapy. | Ophthalmology 20040201 |
| Role of membrane potential and expression of endothelial factors in restenosis after angioplasty in SHR. | Hypertension (Dallas, Tex. : 1979) 20040101 |
| Randomised controlled trial comparing the effect of brimonidine and timolol on visual field loss after acute primary angle closure. | The British journal of ophthalmology 20040101 |
| Patient persistency with topical ocular hypotensive therapy in a managed care population. | American journal of ophthalmology 20040101 |
| Observed time between prescription refills for newer ocular hypotensive agents: the effect of bottle size. | American journal of ophthalmology 20040101 |
| Ocular and systemic side effects of brimonidine 0.2% eye drops (Alphagan) in children. | Eye (London, England) 20040101 |
| Systemic side effects of ophthalmic drops. | Clinical pediatrics 20040101 |
| [Neuroprotection and vasoprotection in glaucoma]. | Oftalmologia (Bucharest, Romania : 1990) 20040101 |
| Effect of latanoprost 0.005% and brimonidine 0.2% on intraocular pressure after phacoemulsification and intraocular lens implantation surgery. | Japanese journal of ophthalmology 20040101 |
| [Latanoprost topical ophthalmic combinations]. | Oftalmologia (Bucharest, Romania : 1990) 20040101 |
| All three alpha2-adrenoceptor types serve as autoreceptors in postganglionic sympathetic neurons. | Naunyn-Schmiedeberg's archives of pharmacology 20031201 |
| Short posterior ciliary artery, central retinal artery, and choroidal hemodynamics in brimonidine-treated primary open-angle glaucoma patients. | American journal of ophthalmology 20031201 |
| Influence of alpha2-autoreceptor stimulation on the facilitation by angiotensin II and bradykinin of noradrenaline release. | Naunyn-Schmiedeberg's archives of pharmacology 20031201 |
| Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: a case for neuroprotection. | The British journal of ophthalmology 20031201 |
| Efficacy of brimonidine 0.2% in controlling acute postoperative intraocular pressure elevation after phacoemulsification. | Journal of cataract and refractive surgery 20031201 |
| Efficacy and safety of brimonidine, dorzolamide and latanoprost as adjunctive therapy in primary open angle glaucoma. | International journal of clinical practice 20031201 |
| Transient ischemia of the retina results in massive degeneration of the retinotectal projection: long-term neuroprotection with brimonidine. | Experimental neurology 20031201 |
| Role of alpha2-adrenergic receptors and cyclic adenosine monophosphate-dependent protein kinase in the regulation of norepinephrine release in the central nervous system of spontaneously hypertensive rats. | Journal of cardiovascular pharmacology 20031201 |
| No evidence for activation of alpha(2)-adrenoceptors by methanolic extracts of bovine brain and lung containing clonidine-displacing substance. | Annals of the New York Academy of Sciences 20031201 |
| Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors. | Annals of the New York Academy of Sciences 20031201 |
| Norepinephrine activates extracellular-regulated kinase in cortical neurons. | Biological psychiatry 20031115 |
| Bilateral simultaneous anterior ischemic optic neuropathy in a young, healthy man. | Archives of ophthalmology (Chicago, Ill. : 1960) 20031101 |
| Bilateral nongranulomatous anterior uveitis associated with bimatoprost. | Journal of cataract and refractive surgery 20031101 |
| Effect of puberty on coronary arteries from female pigs. | Journal of applied physiology (Bethesda, Md. : 1985) 20031001 |
| Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20031001 |
| Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20031001 |
| (+)-Nantenine isolated from Nandina domestica Thunb. inhibits adrenergic pressor responses in pithed rats. | European journal of pharmacology 20030905 |
| Endothelium-dependent responses in coronary arteries are changed with puberty in male pigs. | American journal of physiology. Heart and circulatory physiology 20030901 |
| Does topical brimonidine tartrate help NAION? | The British journal of ophthalmology 20030901 |
| Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor. | British journal of pharmacology 20030901 |
| Evaluation of an immortalized retinal endothelial cell line as an in vitro model for drug transport studies across the blood-retinal barrier. | Pharmaceutical research 20030901 |
| Dermatological side effects of brimonidine: a report of three cases. | The Journal of dermatology 20030901 |
| Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes. | Molecular endocrinology (Baltimore, Md.) 20030801 |
| Evaluation of neuroprotective qualities of brimonidine during LASIK. | Ophthalmology 20030801 |
| Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries. | American journal of physiology. Heart and circulatory physiology 20030701 |
| Role of the alpha2-adrenoceptors on the pulmonary circulation in the ovine fetus. | Pediatric research 20030701 |
| Charles Bonnet syndrome precipitated by brimonidine tartrate eye drops. | The British journal of ophthalmology 20030701 |
| Medical therapy cost considerations for glaucoma. | American journal of ophthalmology 20030701 |
| DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice. | Pain 20030701 |
| Granulomatous anterior uveitis associated with 0.2% topical brimonidine. | Eye (London, England) 20030701 |
| Patient persistency with pharmacotherapy in the management of glaucoma. | European journal of ophthalmology 20030701 |
| Changes in medical and surgical treatments of glaucoma between 1997 and 2000 in France. | European journal of ophthalmology 20030701 |
| Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304). | The Journal of pharmacology and experimental therapeutics 20030601 |
| Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism. | The Journal of pharmacology and experimental therapeutics 20030601 |
| Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily. | Acta ophthalmologica Scandinavica 20030601 |
| Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030601 |
| Comparison between latanoprost and brimonidine efficacy and safety in Indian eyes. | Indian journal of ophthalmology 20030601 |
| A novel D2-dopaminergic and alpha2-adrenoceptor receptor agonist induces substantial and prolonged IOP decrease in normotensive rabbits. | The Journal of pharmacy and pharmacology 20030601 |
| Pregnancy-associated changes in responsiveness of the porcine myometrium to bioactive substances. | European journal of pharmacology 20030523 |
| Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments. | Brain research bulletin 20030515 |
| alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats. | The Journal of pharmacology and experimental therapeutics 20030501 |
| Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide. | The British journal of ophthalmology 20030501 |
| Enhancement of alpha2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery: role of the ERK-MAP kinase signal transduction cascade. | British journal of pharmacology 20030501 |
| Altered prejunctional modulation of intestinal cholinergic and noradrenergic pathways by alpha2-adrenoceptors in the presence of experimental colitis. | British journal of pharmacology 20030501 |
| The efficacy and safety of brimonidine 0.2% compared with timolol 0.5% in glaucoma: a randomized clinical trial on Taiwanese patients. | Journal of the Chinese Medical Association : JCMA 20030501 |
| Regulation of Cl- secretion by alpha2-adrenergic receptors in mouse colonic epithelium. | The Journal of physiology 20030415 |
| A 24-day old with episodic lethargy, hypotonia, and apnea: the eyes have it. | Current opinion in pediatrics 20030401 |
| Cystoid macular oedema associated with brimonidine therapy. | Clinical & experimental ophthalmology 20030401 |
| Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: a dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors. | The Journal of pharmacology and experimental therapeutics 20030401 |
| The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension. | Archives of ophthalmology (Chicago, Ill. : 1960) 20030401 |
| The effects of latanoprost and brimonidine on blood flow velocity of the retrobulbar vessels: a 3-month clinical trial. | Acta ophthalmologica Scandinavica 20030401 |
| Presynaptic regulation of neurotransmitter release in the cortex of aged rats with differential memory impairments. | Pharmacology, biochemistry, and behavior 20030401 |
| [The effect of brimonidine on postoperative hypertonia after an extracapsular cataract extraction]. | Journal francais d'ophtalmologie 20030401 |
| Role of alpha-2 agonists in neuroprotection. | Survey of ophthalmology 20030401 |
| Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability. | Ophthalmology 20030301 |
| Desensitization of alpha 2A-adrenoceptor signalling by modest levels of adrenaline is facilitated by beta 2-adrenoceptor-dependent GRK3 up-regulation. | British journal of pharmacology 20030301 |
| Miotic effect of alphagan P. | Journal of cataract and refractive surgery 20030301 |
| Four years later: a clinical update on latanoprost. | European journal of ophthalmology 20030301 |
| alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs. | European journal of pharmacology 20030221 |
| Readability of ocular medication inserts. | Journal of glaucoma 20030201 |
| New topical drugs for open-angle glaucoma. | Drug and therapeutics bulletin 20030201 |
| Characterization of alpha2-adrenoceptors in smooth muscles of the spontaneously hypertensive rat aorta. | Vascular pharmacology 20030201 |
| A 3-month comparison of efficacy and safety of brimonidine-purite 0.15% and brimonidine 0.2% in patients with glaucoma or ocular hypertension. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030201 |
| Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20030201 |
| Neurotransmitter release and its presynaptic modulation in the rat hippocampus after selective damage to cholinergic or/and serotonergic afferents. | Brain research bulletin 20030130 |
| Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension. | American journal of physiology. Heart and circulatory physiology 20030101 |
| A paradoxical ocular effect of brimonidine. | American journal of ophthalmology 20030101 |
| Brimonidine and latanoprost as adjunctive therapy. | Ophthalmology 20030101 |
| Regulation of leptin release by insulin, glucocorticoids, G(i)-coupled receptor agonists, and pertussis toxin in adipocytes and adipose tissue explants from obese humans in primary culture. | Metabolism: clinical and experimental 20030101 |
| Consultation section. Refractive surgical problem: 3 issues to be discussed: the clinical indications, the surgical procedure, the postoperative findings. | Journal of cataract and refractive surgery 20030101 |
| Ocular perfusion pressure and visual field indice modifications induced by alpha-agonist compound (clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2%) topical administration. An acute study on primary open-angle glaucoma patients. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101 |
| Nurse prescribing in glaucoma. | Eye (London, England) 20030101 |
| [Increased myopia and metaporphosia in a 59-year old patient. Serous retinal detachment of the posterior pol after latanoprost administration]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20030101 |
| Brimonidine Purite and bimatoprost compared with timolol and latanoprost in patients with glaucoma and ocular hypertension. | Advances in therapy 20030101 |
| Latanoprost : an update of its use in glaucoma and ocular hypertension. | Drugs & aging 20030101 |
| Comparison of brimonidine/latanoprost and timolol/dorzolamide: two randomized, double-masked, parallel clinical trials. | Advances in therapy 20030101 |
| Brimonidine formulation in polyacrylic acid nanoparticles for ophthalmic delivery. | Journal of microencapsulation 20030101 |
| A short-term study of the additive effect of latanoprost 0.005% and brimonidine 0.2%. | Japanese journal of ophthalmology 20030101 |
| Prophylactic brimonidine before LASIK. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20030101 |
| Effect of brimonidine on intraocular pressure in normal tension glaucoma: a short term clinical trial. | European journal of ophthalmology 20030101 |
| A new measure of patient satisfaction with ocular hypotensive medications: the Treatment Satisfaction Survey for Intraocular Pressure (TSS-IOP). | Health and quality of life outcomes 20030101 |
| Vision related quality of life and topical glaucoma treatment side effects. | Health and quality of life outcomes 20030101 |
| Evaluation of the comfort of Alphagan P compared with Alphagan in irritated eyes. | Advances in therapy 20030101 |
| Alpha 2-Adrenergic stimulation is protective against ischemia-reperfusion-induced ventricular arrhythmias in vivo. | American journal of physiology. Heart and circulatory physiology 20021201 |
| Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. | The Journal of pharmacology and experimental therapeutics 20021201 |
| Effect of single and multiple doses of 0.2% brimonidine tartrate in the glaucomatous Beagle. | Veterinary ophthalmology 20021201 |
| Changes in intraocular pressure and ocular perfusion pressure after latanoprost 0.005% or brimonidine tartrate 0.2% in normal-tension glaucoma patients. | Ophthalmology 20021201 |
| The short-term IOP-lowering effect of brimonidine 0.2% and dorzolomide 2% combination in primary open-angle glaucoma. | Acta ophthalmologica Scandinavica 20021201 |
| Transient ischemia of the retina results in altered retrograde axoplasmic transport: neuroprotection with brimonidine. | Experimental neurology 20021201 |
| Nitric oxide discriminates the sites and mechanisms of action of centrally acting anti-hypertensive drugs in rabbits. | Neuropharmacology 20021201 |
| Evaluation of the intraocular pressure-reducing effect of latanoprost as monotherapy in open-angle glaucoma. | Collegium antropologicum 20021201 |
| Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucoma. | The British journal of ophthalmology 20021101 |
| Effects of the imidazoline ligands efaroxan and KU14R on blood glucose homeostasis in the mouse. | European journal of pharmacology 20021101 |
| Pharmacological evidence of a role for prejunctional imidazoline (I(1)) receptors in ocular function. | Current eye research 20021101 |
| Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta. | American journal of physiology. Heart and circulatory physiology 20021001 |
| Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta. | American journal of physiology. Heart and circulatory physiology 20021001 |
| Effect of a long-duration physical exercise on fat cell lipolytic responsiveness to adrenergic agents and insulin in obese men. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20021001 |
| Different contractile effects of alpha1- and alpha2-adrenergic agonists on horse isolated common digital artery smooth muscle ring preparations in vitro. | Pharmacological research 20021001 |
| Iatrogenic ring scotoma after laser in situ keratomileusis. | Journal of cataract and refractive surgery 20021001 |
| Beta-adrenoceptor-induced inhibition of rat splenocyte proliferation: cytokine gene transcription as the target of action. | Immunobiology 20021001 |
| Sympathetic denervation-induced changes in G protein expression in enteric neurons of the guinea pig colon. | Life sciences 20020913 |
| Beta 3-adrenoceptor in rat aorta: molecular and biochemical characterization and signalling pathway. | British journal of pharmacology 20020901 |
| Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia. | Journal of leukocyte biology 20020901 |
| Effect of treatment by medicine or surgery on intraocular pressure and pulsatile ocular blood flow in normal-pressure glaucoma. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020901 |
| Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model. | Vision research 20020901 |
| Reappraising first-line treatment in glaucoma management. | Hospital medicine (London, England : 1998) 20020901 |
| Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina. | Investigative ophthalmology & visual science 20020801 |
| Inhibition by brimonidine of forskolin-induced nitrite production in isolated pig ciliary processes. | Investigative ophthalmology & visual science 20020801 |
| Cost analysis of glaucoma medications: a 3-year review. | Journal of glaucoma 20020801 |
| An economic analysis of switching to latanoprost from a beta-blocker or adding brimonidine or latanoprost to a beta-blocker in open-angle glaucoma or ocular hypertension. | The American journal of managed care 20020801 |
| Rates of discontinuation and change of glaucoma therapy in a managed care setting. | The American journal of managed care 20020801 |
| Discontinuation rates of topical glaucoma medications in a managed care population. | The American journal of managed care 20020801 |
| Medical treatment of normal tension glaucoma. | Survey of ophthalmology 20020801 |
| Formulation effects on ocular absorption of brimonidine in rabbit eyes. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020801 |
| Efficacy of brimonidine 0.2 per cent as adjunctive therapy to beta-blockers: a comparative study between POAG and CACG in Asian eyes. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020801 |
| Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries. | Fundamental & clinical pharmacology 20020801 |
| Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues. | European journal of pharmacology 20020712 |
| Naphazoline-induced neuroendocrine changes: increases in ANP and cGMP levels, but suppression of NE, 3H-NE, and cAMP levels in rabbit eyes. | Pharmacology 20020701 |
| Effect of hyaluronic acid on intraocular pressure in rats. | Investigative ophthalmology & visual science 20020701 |
| [Clinical efficacy of 0.2% brimonidine in patients with open-angle glaucoma or ocular hypertension]. | Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20020628 |
| Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries. | American journal of physiology. Regulatory, integrative and comparative physiology 20020601 |
| Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities. | Hepatology (Baltimore, Md.) 20020601 |
| Additive intraocular pressure lowering effect of various medications with latanoprost. | American journal of ophthalmology 20020601 |
| Scleritis as the initial clinical manifestation of graft-versus-host disease after allogenic bone marrow transplantation. | American journal of ophthalmology 20020601 |
| Up-regulation of brain-derived neurotrophic factor expression by brimonidine in rat retinal ganglion cells. | Archives of ophthalmology (Chicago, Ill. : 1960) 20020601 |
| Cardiovascular effects of timolol maleate, brimonidine or brimonidine/timolol maleate in concomitant therapy. | Acta ophthalmologica Scandinavica 20020601 |
| [Use of brimonidine 0.2% in treatment of glaucoma or ocular hypertony after poorly tolerated beta-blocker treatment]. | Journal francais d'ophtalmologie 20020601 |
| alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation. | The Journal of biological chemistry 20020531 |
| Mutagenesis and peptide analysis of the DRY motif in the alpha2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors. | Biochemical and biophysical research communications 20020517 |
| ATP release in human kidney cortex and its mitogenic effects in visceral glomerular epithelial cells. | Kidney international 20020501 |
| The effects of new topical treatments on management of glaucoma in Scotland: an examination of ophthalmological health care. | The British journal of ophthalmology 20020501 |
| Brimonidine 0.2% to prevent post laser IOP elevation. | Ophthalmology 20020501 |
| Release inhibitory receptors activation favours the A2A-adenosine receptor-mediated facilitation of noradrenaline release in isolated rat tail artery. | British journal of pharmacology 20020501 |
| New glaucoma medications in the geriatric population: efficacy and safety. | Journal of the American Geriatrics Society 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Distribution of brimonidine into anterior and posterior tissues of monkey, rabbit, and rat eyes. | Drug metabolism and disposition: the biological fate of chemicals 20020401 |
| Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents. | The Journal of pharmacology and experimental therapeutics 20020401 |
| Intraocular pressure-lowering effects of latanoprost and brimonidine therapy in patients with open-angle glaucoma or ocular hypertension: a randomized observer-masked multicenter study. | Journal of glaucoma 20020401 |
| Twelve-month evaluation of brimonidine-purite versus brimonidine in patients with glaucoma or ocular hypertension. | Journal of glaucoma 20020401 |
| The efficacy of brimonidine in preventing intraocular pressure elevation in the provocative test for primary angle-closure glaucoma. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020401 |
| Failure of naloxone to reverse brimonidine-induced coma in an infant. | The Journal of pediatrics 20020401 |
| Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro. | Experimental physiology 20020301 |
| Delayed hypersensitivity to brimonidine tartrate 0.2% associated with high intraocular pressure. | Eye (London, England) 20020301 |
| Oral toxicity of topical preparations. | The Veterinary clinics of North America. Small animal practice 20020301 |
| Clinical effects of brimonidine ophthalmic drops ingestion in 52 dogs. | Veterinary and human toxicology 20020201 |
| Three-month comparison of brimonidine and latanoprost as adjunctive therapy in glaucoma and ocular hypertension patients uncontrolled on beta-blockers: tolerance and peak intraocular pressure lowering. | Ophthalmology 20020201 |
| Substance P, insulinlike growth factor 1, and surface healing. | Archives of ophthalmology (Chicago, Ill. : 1960) 20020201 |
| Lysophosphatidylcholine potentiates vascular contractile responses in rat aorta via activation of tyrosine kinase. | British journal of pharmacology 20020201 |
| Allergic reactions to brimonidine in patients treated for glaucoma. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20020201 |
| Neuroprotective effects of brimonidine against transient ischemia-induced retinal ganglion cell death: a dose response in vivo study. | Experimental eye research 20020201 |
| Modification of serotonin neuron properties in mice lacking 5-HT1A receptors. | European journal of pharmacology 20020125 |
| Tumor necrosis factor expressed by primary hippocampal neurons and SH-SY5Y cells is regulated by alpha(2)-adrenergic receptor activation. | Journal of neuroscience research 20020115 |
| alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy. | The Journal of pharmacology and experimental therapeutics 20020101 |
| Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy. | American journal of ophthalmology 20020101 |
| Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach. | British journal of pharmacology 20020101 |
| Minimally invasive spectroscopic system for intraocular drug detection. | Journal of biomedical optics 20020101 |
| A comparison of the short-term hypotensive effects and side effects of unilateral brimonidine and apraclonidine in patients with elevated intraocular pressure. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101 |
| A short term study of the additive effect of timolol and brimonidine on intraocular pressure. | Eye (London, England) 20020101 |
| Brimonidine .2% as a replacement for beta blockers in geriatric patients with glaucoma. | Advances in therapy 20020101 |
| Effect of prophylactic brimonidine on bleeding complications and flap adherence after laser in situ keratomileusis. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20020101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020101 |
| Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat. | Visual neuroscience 20020101 |
| Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma. | Acta ophthalmologica Scandinavica. Supplement 20020101 |
| Effect of brimonidine on patients undergoing uncontrolled IOP with beta-blockers. | Acta ophthalmologica Scandinavica. Supplement 20020101 |
| Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension. | Acta ophthalmologica Scandinavica. Supplement 20020101 |
| Endothelial inhibitory modulation on the contractile responses to alpha 2-adrenergic agonists. | Proceedings of the Western Pharmacology Society 20020101 |
| Vasocontractile effects of alpha 2-adrenergic agonists associated with intracellular calcium release. | Proceedings of the Western Pharmacology Society 20020101 |
| Changes of the excitability of rat trigeminal root ganglion neurons evoked by alpha(2)-adrenoreceptors. | Neuroscience 20020101 |
| The impact of new drugs on management of glaucoma in Scotland: observational study. | BMJ (Clinical research ed.) 20011215 |
| Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors. | European journal of pharmacology 20011207 |
| A comparison of the efficacy and tolerability of brimonidine and latanoprost in adults with open-angle glaucoma or ocular hypertension: a three-month, multicenter, randomized, double-masked, parallel-group trial. | Clinical therapeutics 20011201 |
| [New medical treatments of glaucoma. New strategies?]. | Journal francais d'ophtalmologie 20011201 |
| [The ocular hypotensive effect and safety of 0.2% brimonidine]. | Yan ke xue bao = Eye science 20011201 |
| Functional characterization of alpha1-adrenoceptor subtypes in human subcutaneous resistance arteries. | The Journal of pharmacology and experimental therapeutics 20011101 |
| Ca2+ influx mediates enhanced alpha2-adrenergic contraction in aortas from rats treated with NOS inhibitor. | American journal of physiology. Heart and circulatory physiology 20011101 |
| Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. | Investigative ophthalmology & visual science 20011101 |
| alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator. | British journal of pharmacology 20011001 |
| Safety and efficacy of brimonidine in children with glaucoma. | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20011001 |
| [Brimonidine absorption and release from 1. Day acuvue disposable contact lenses]. | Archivos de la Sociedad Espanola de Oftalmologia 20011001 |
| [Prospects for neuroprotective glaucoma therapy]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011001 |
| [Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011001 |
| Circadian change of adenylate cyclase activity in rabbit ciliary processes. | Current eye research 20011001 |
| Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure. | Brain research 20010921 |
| Effects of central imidazolinergic and alpha2-adrenergic activation on water intake. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010901 |
| Enhanced interaction between renovascular alpha(2)-adrenoceptors and angiotensin II receptors in genetic hypertension. | Hypertension (Dallas, Tex. : 1979) 20010901 |
| Acute and chronic effects of brimonidine 0.2% on intraocular pressure and pulsatile ocular blood flow in patients with primary open-angle glaucoma: an open-label, uncontrolled, prospective study. | Clinical therapeutics 20010901 |
| [Experience with topical brimonidine in the treatment of glaucomas]. | Journal francais d'ophtalmologie 20010901 |
| Systemic beta-blocker therapy and brimonidine and timolol. | Ophthalmology 20010801 |
| The adverse effect of perioperative brimonidine tartrate 0.2% on flap adherence and enhancement rates in laser in situ keratomileusis patients. | Ophthalmology 20010801 |
| Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries. | Investigative ophthalmology & visual science 20010801 |
| Neuroprotective effects of alpha(2)-selective adrenergic agonists against ischemia-induced retinal ganglion cell death. | Investigative ophthalmology & visual science 20010801 |
| Effect of topical brimonidine on intraocular pressure after small incision cataract surgery. | Journal of cataract and refractive surgery 20010801 |
| Clinical and economic impact of new trends in glaucoma treatment. | MedGenMed : Medscape general medicine 20010726 |
| Role of alpha(2)-adrenoceptors in the sympathetic inhibition of motility reflexes of guinea-pig ileum. | The Journal of physiology 20010715 |
| The effect of adrenergic compounds on neurogenic dural vasodilatation. | European journal of pharmacology 20010713 |
| Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum. | British journal of pharmacology 20010701 |
| Role of the extracellular signal-regulated kinase (Erk) signal transduction cascade in alpha(2) adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein. | British journal of pharmacology 20010701 |
| Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25 % suspension in patients with elevated intraocular pressure. | Clinical therapeutics 20010701 |
| Comparative effects of antiglaucoma drugs on voltage-dependent calcium channels. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010701 |
| The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries. | European journal of pharmacology 20010622 |
| Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors. | Brain research 20010615 |
| Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery. | Ophthalmology 20010601 |
| Brimonidine 0.2% given two or three times daily versus timolol maleate 0.5% in primary open-angle glaucoma. | American journal of ophthalmology 20010601 |
| Washout periods for brimonidine 0.2% and latanoprost 0.005%. | American journal of ophthalmology 20010601 |
| Effect of brimonidine tartrate on ocular hemodynamics in healthy volunteers. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601 |
| Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601 |
| Effectiveness and safety of brimonidine as adjunctive therapy for patients with elevated intraocular pressure in a large, open-label community trial. | Journal of glaucoma 20010601 |
| Quantitation of mitomycin C in human ocular tissues by high-performance liquid chromatography-photo-diode array detection. | Journal of chromatography. B, Biomedical sciences and applications 20010505 |
| The efficacy and safety of latanoprost 0.005% once daily versus brimonidine 0.2% twice daily in open-angle glaucoma or ocular hypertension. | American journal of ophthalmology 20010501 |
| Retinal ganglion cell death induced by retinal ischemia. neuroprotective effects of two alpha-2 agonists. | Survey of ophthalmology 20010501 |
| Maintaining mitochondrial membrane impermeability. an opportunity for new therapy in glaucoma? | Survey of ophthalmology 20010501 |
| Role of alpha-2 adrenergic receptors in neuroprotection and glaucoma. | Survey of ophthalmology 20010501 |
| Brimonidine and inhibition of nitrite production in isolated porcine ciliary processes. | Klinische Monatsblatter fur Augenheilkunde 20010501 |
| Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery. | British journal of pharmacology 20010401 |
| Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA. | British journal of pharmacology 20010401 |
| Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination. | Archives of ophthalmology (Chicago, Ill. : 1960) 20010401 |
| Effects of dietary L-arginine on structure and function of flow-restricted vein grafts. | Journal of vascular surgery 20010401 |
| Vitreous concentration of topically applied brimonidine tartrate 0.2%. | Ophthalmology 20010401 |
| Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions. | Journal of cataract and refractive surgery 20010401 |
| Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension. | Clinical therapeutics 20010401 |
| Effects of verapamil and elgodipine on isoprenaline-induced metabolic responses in rabbits. | European journal of pharmacology 20010309 |
| Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning. | Cardiovascular research 20010301 |
| Ophthalmic drops causing coma in an infant. | The Journal of pediatrics 20010301 |
| [Neuroprotection. Bases and possibilities of a future clinical use]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010301 |
| Effect of 0.2% brimonidine on retinal blood flow. | Yan ke xue bao = Eye science 20010301 |
| Postjunctional alpha(2C)-adrenoceptor contractility in human saphenous vein. | European journal of pharmacology 20010216 |
| A robust GTP-induced shift in alpha(2)-adrenoceptor agonist affinity in tissue sections from rat brain. | Journal of neuroscience methods 20010215 |
| Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. | Pain 20010201 |
| Receptor reserve analysis of the human alpha(2C)-adrenoceptor using. | European journal of pharmacology 20010112 |
| Influence of nitric oxide donors and of the alpha(2)-agonist UK-14,304 on acetylcholine release in the pig gastric fundus. | Neuropharmacology 20010101 |
| Increased alpha(1)- and alpha(2)-adrenoceptor-mediated contractile responses of human skeletal muscle resistance arteries in chronic limb ischemia. | Cardiovascular research 20010101 |
| alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia. | The Journal of pharmacology and experimental therapeutics 20010101 |
| Alpha2-adrenoceptor-mediated inhibition of cultured sympathetic neurons: changes in alpha2A/D-adrenoceptor-deficient mice. | Naunyn-Schmiedeberg's archives of pharmacology 20010101 |
| Effects of acute and chronic ethanol administration on the response of mouse adipose tissue hormone-sensitive lipase to alpha(2)-adrenoceptor activation bu UK 14304. | Alcohol and alcoholism (Oxford, Oxfordshire) 20010101 |
| Apoptosis and anti-apoptosis signalling in glaucomatous retinopathy. | European journal of ophthalmology 20010101 |
| Alpha-2 adrenergic receptor agonists are neuroprotective in experimental models of glaucoma. | European journal of ophthalmology 20010101 |
| Brimonidine's neuroprotective effects against transient ischaemia-induced retinal ganglion cell death. | European journal of ophthalmology 20010101 |
| Influence of topical brimonidine on visual field in glaucoma. | European journal of ophthalmology 20010101 |
| Brimonidine (Alphagan): a clinical profile four years after launch. | European journal of ophthalmology 20010101 |
| Switching patients with glaucoma or ocular hypertension from dual therapy to monotherapy: evaluation of brimonidine as a model. | Advances in therapy 20010101 |
| Antiglaucomatous drugs effects on optic nerve head flow: design, baseline and preliminary report. | International ophthalmology 20010101 |
| Does glaucoma medication influence the diameter of the retinal arteriole in the human eye? (A pilot study using the retinal vessel analyser). | Acta physiologica Hungarica 20010101 |
| Incidence of brimonidine allergy in patients previously allergic to apraclonidine. | Journal of glaucoma 20000601 |
| Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors. | British journal of pharmacology 20000401 |
| Platelet alpha2-adrenoceptor alterations in patients with essential hypertension are normalized after treatment with doxazosin but not propranolol. | Journal of hypertension 20000201 |
| Mechanisms of action of OPC-28326, a selective hindlimb vasodilator. | The Journal of pharmacology and experimental therapeutics 19991101 |
| Modulation of agonist binding to recombinant human alpha2-adrenoceptors by sodium ions. | Biochimica et biophysica acta 19981119 |
| Subtype-specific stimulation of [35S]GTPgammaS binding by recombinant alpha2-adrenoceptors. | European journal of pharmacology 19980821 |
| Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. | Biochemical pharmacology 19980401 |
| Gene targeting--homing in on alpha 2-adrenoceptor-subtype function. | Trends in pharmacological sciences 19970601 |
| The inhibitory effects of alpha(2)-adrenoceptor agonists on gastrointestinal transit during croton oil-induced intestinal inflammation. | British journal of pharmacology 19961201 |
| Clinical experience with brimonidine 0.2% and timolol 0.5% in glaucoma and ocular hypertension. | Survey of ophthalmology 19961101 |
| The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons. | Molecular pharmacology 19960901 |
| Naloxone-induced potentiation of cardiac alpha-2 adrenoceptor-mediated depression of neurogenic tachycardia. | The Journal of pharmacology and experimental therapeutics 19930701 |
| Presynaptic alpha 2-autoreceptors in brain cortex: alpha 2D in the rat and alpha 2A in the rabbit. | Naunyn-Schmiedeberg's archives of pharmacology 19930701 |
| In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist. | European journal of pharmacology 19930406 |
| Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors. | The Journal of pharmacology and experimental therapeutics 19921201 |
| Single potassium channels opened by opioids in rat locus ceruleus neurons. | Proceedings of the National Academy of Sciences of the United States of America 19890501 |
| Noradrenergic influences on sound-induced seizures. | The Journal of pharmacology and experimental therapeutics 19800801 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.