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59-52-9 | 2,3-Dimercapto-1-propanol
CAS No: 59-52-9 Catalog No: AG003FJB MDL No:MFCD00004864
Product Description
Catalog Number:
AG003FJB
Chemical Name:
2,3-Dimercapto-1-propanol
CAS Number:
59-52-9
Molecular Formula:
C3H8OS2
Molecular Weight:
124.2250
MDL Number:
MFCD00004864
IUPAC Name:
2,3-bis(sulfanyl)propan-1-ol
InChI:
InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2
InChI Key:
WQABCVAJNWAXTE-UHFFFAOYSA-N
SMILES:
OCC(CS)S
EC Number:
200-433-7
UN Number:
2810
Properties
Complexity:
32
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
124.002g/mol
Formal Charge:
0
Heavy Atom Count:
6
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
124.216g/mol
Monoisotopic Mass:
124.002g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
22.2A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2
Literature
| Title | Journal |
|---|---|
| Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. | Proceedings of the National Academy of Sciences of the United States of America 20151208 |
| Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. | Toxicology and applied pharmacology 20131115 |
| Reversal effect of monoisoamyl dimercaptosuccinic acid (MiADMSA) for arsenic and lead induced perturbations in apoptosis and antioxidant enzymes in developing rat brain. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20131101 |
| α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs. | European journal of pharmacology 20130405 |
| 2,3-Dimercaptopropanol, a thiol chelator, alleviates gastroduodenal ulcers in rats. | Fundamental & clinical pharmacology 20120601 |
| Molecular determinants and dynamics of hepatitis C virus secretion. | PLoS pathogens 20120101 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Superhydrophobic fiber mats by electrodeposition of fluorinated poly(3,4-ethyleneoxythiathiophene). | Journal of the American Chemical Society 20111005 |
| In vitro efficacy of bismuth thiols against biofilms formed by bacteria isolated from human chronic wounds. | Journal of applied microbiology 20111001 |
| Bismuth dimercaptopropanol (BisBAL) inhibits formation of multispecies wastewater flocs. | Journal of applied microbiology 20110601 |
| Inadvertent poisoning of seven teenagers with monosodium methanearsonate. | Clinical toxicology (Philadelphia, Pa.) 20110301 |
| Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101 |
| Identification of clinically used drugs that activate pregnane X receptors. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Tetracysteine-based fluorescent tags to study protein localization and trafficking in Plasmodium falciparum-infected erythrocytes. | PloS one 20110101 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Fatal mercury poisoning and chelating agents. | Forensic science international 20101010 |
| Display of both N- and C-terminal target fusion proteins on the Aspergillus oryzae cell surface using a chitin-binding module. | Applied microbiology and biotechnology 20100801 |
| Chelation in metal intoxication. | International journal of environmental research and public health 20100701 |
| Images in toxicology: girl with constipation. | Clinical toxicology (Philadelphia, Pa.) 20100601 |
| Evaluation of cations and chelating agents as extracellular extractants for Cu, Pb, V and Zn in the sequential elution technique applied to the terrestrial moss Pseudoscleropodium purum. | Ecotoxicology and environmental safety 20100501 |
| Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2. | The Journal of pharmacology and experimental therapeutics 20100101 |
| Synthesis, X-Ray Structure, and Characterization of Catena-bis(benzoate)bis{N,N-bis(2-hydroxyethyl)glycinate}cadmium(II). | Bioinorganic chemistry and applications 20100101 |
| Detoxification of mercury species--an in vitro study with antidotes in human whole blood. | Analytical and bioanalytical chemistry 20091101 |
| Pattern-based recognition of thiols and metals using a single squaraine indicator. | Journal of the American Chemical Society 20090916 |
| The conquest of Wilson's disease. | Brain : a journal of neurology 20090801 |
| Reaction of the catalytic cysteine of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with arsenite-BAL and phenylarsine oxide. | Chemico-biological interactions 20090316 |
| Regulation of fast skeletal muscle activity by SERCA1 vicinal-cysteines. | Journal of muscle research and cell motility 20090101 |
| Acute mercury intoxication and use of chelating agents. | Journal of biological regulators and homeostatic agents 20090101 |
| Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure. | Oxidative medicine and cellular longevity 20090101 |
| Quantification of arsenic compounds using derivatization, solvent extraction and liquid chromatography electrospray ionization tandem mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20081215 |
| Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
| Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles. | Proceedings of the National Academy of Sciences of the United States of America 20081014 |
| Quadriplegia due to lead-contaminated opium--case report. | Middle East journal of anaesthesiology 20081001 |
| Choreoathetosis secondary to lead toxicity. | Arquivos de neuro-psiquiatria 20080901 |
| Phosphatidylinositol kinases as regulators of GA-stimulated alpha-amylase secretion in barley (Hordeum vulgare). | Physiologia plantarum 20080601 |
| The role of thiol-reducing agents on modulation of glutamate binding induced by heavy metals in platelets. | Toxicology in vitro : an international journal published in association with BIBRA 20080301 |
| Bismuth dimercaptopropanol (BisBAL) inhibits the expression of extracellular polysaccharides and proteins by Brevundimonas diminuta: implications for membrane microfiltration. | Biotechnology and bioengineering 20080215 |
| Selective masking and demasking for the stepwise complexometric determination of aluminium, lead and zinc from the same solution. | Chemistry Central journal 20080101 |
| Study on the interaction between 2-mercaptoethanol, dimercaprol and CdSe quantum dots. | Luminescence : the journal of biological and chemical luminescence 20080101 |
| Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH. | Nature chemical biology 20071201 |
| Successful treatment of potentially fatal heavy metal poisonings. | The Journal of emergency medicine 20070401 |
| Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review. | Journal of environmental biology 20070401 |
| [Two different clinical cases of acute arsenic trioxide intoxication]. | Przeglad lekarski 20070101 |
| Depolarization-evoked secretion requires two vicinal transmembrane cysteines of syntaxin 1A. | PloS one 20070101 |
| Complex inhibition of tyrosinase by thiol-composed Cu2+ chelators: a clue for designing whitening agents. | Journal of biomolecular structure & dynamics 20061001 |
| Photochemistry of the [Fe4(mu3-S)3(NO)7]- complex in the presence of S-nucleophiles: a spectroscopic study. | Nitric oxide : biology and chemistry 20060501 |
| 2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid increase lead-induced inhibition of delta-aminolevulinate dehydratase in vitro and ex vivo. | Toxicology in vitro : an international journal published in association with BIBRA 20060401 |
| Microarray analysis of mouse ear tissue exposed to bis-(2-chloroethyl) sulfide: gene expression profiles correlate with treatment efficacy and an established clinical endpoint. | The Journal of pharmacology and experimental therapeutics 20060401 |
| Diphenyl diselenide and 2,3-dimercaptopropanol increase the PTZ-induced chemical seizure and mortality in mice. | Brain research bulletin 20060215 |
| TXM13 human melanoma cells: a novel source for the inhibition kinetics of human tyrosinase and for screening whitening agents. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201 |
| Effect of PAO (phenylarsine oxide) on the inhibitory effect of insulin and IGF-1 on insulin release from INS-1 cells. | Endocrine journal 20060201 |
| Arsenic toxicology: five questions. | Chemical research in toxicology 20060101 |
| Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex. | The Journal of biological chemistry 20051125 |
| Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography. | Journal of the American Chemical Society 20050831 |
| Switching of the electronic communication between two {Ru(trpy)(bpy)} (trpy = 2,2':6',2' '-terpyridine and bpy = 2,2'-bipyridine) centers by protonation on the bridging dimercaptothiadiazolato ligand. | Inorganic chemistry 20050725 |
| The need for vigilance: the persistence of lead poisoning in children. | Pediatrics 20050601 |
| Inhibition of bacterial adherence on the surface of stents and bacterial growth in bile by bismuth dimercaprol. | Digestive diseases and sciences 20050601 |
| 2,3-Dimercapto-1-propanol does not alter the porphobilinogen synthase inhibition but decreases the mercury content in liver and kidney of suckling rats exposed to HgCl2. | Basic & clinical pharmacology & toxicology 20050401 |
| 2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid acute administration diferentially change biochemical parameters in mice. | Basic & clinical pharmacology & toxicology 20050401 |
| Toxicity induced by Hg2+ on choline acetyltransferase activity from E. electricus (L.) electrocytes: the protective effect of 2,3 dimercapto-propanol (BAL). | Medical science monitor : international medical journal of experimental and clinical research 20050401 |
| Bismuth-dithiol inhibition of the Escherichia coli rho transcription termination factor. | Journal of inorganic biochemistry 20050301 |
| Synthesis and optical properties of thiol-stabilized PbS nanocrystals. | Langmuir : the ACS journal of surfaces and colloids 20050201 |
| Construction and evaluation of drug-metabolizing cell line for bioartificial liver support system. | Biotechnology progress 20050101 |
| Effects of chelating agents on distribution and excretion of terbium in mice. | Toxicology mechanisms and methods 20050101 |
| The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region. | Annals of the New York Academy of Sciences 20041201 |
| Suicidal mercury injection into the upper limb: a case study. | Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand 20041201 |
| Schizophrenia and refractory anaemia with ring sideroblasts. | British journal of haematology 20040601 |
| Combined exchange transfusion and chelation therapy for neonatal lead poisoning. | The Annals of pharmacotherapy 20040501 |
| 2,3-Dimercaptopropanol, 2,3-dimercaptopropane-1-sulfonic acid, and meso-2,3-dimercaptosuccinic acid inhibit delta-aminolevulinate dehydratase from human erythrocytes in vitro. | Environmental research 20040301 |
| Chemical and biological considerations in the treatment of metal intoxications by chelating agents. | Mini reviews in medicinal chemistry 20040101 |
| Gas chromatographic-mass spectrometric determination of british anti-lewisite in plasma. | Journal of analytical toxicology 20040101 |
| FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein. | Journal of molecular neuroscience : MN 20040101 |
| Survival after a lethal dose of arsenic trioxide. | Journal of toxicology. Clinical toxicology 20040101 |
| Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate. | Analytical chemistry 20031201 |
| Interaction between metals and chelating agents affects glutamate binding on brain synaptic membranes. | Neurochemical research 20031201 |
| Neonatal tolerance to a Th2-mediated autoimmune disease generates CD8+ Tc1 regulatory cells. | Journal of autoimmunity 20031101 |
| Syntaxin 1A modulates the voltage-gated L-type calcium channel (Ca(v)1.2) in a cooperative manner. | The Journal of biological chemistry 20030801 |
| A colorimetric microplate assay method for high throughput analysis of lipase activity. | Journal of biochemistry and molecular biology 20030731 |
| Subcutaneous injection of metallic mercury. | Human & experimental toxicology 20030601 |
| Assessment of bismuth thiols and conventional disinfectants on drinking water biofilms. | Journal of applied microbiology 20030101 |
| Drug discovery targeted to the Alzheimer's APP mRNA 5'-untranslated region: the action of paroxetine and dimercaptopropanol. | Journal of molecular neuroscience : MN 20030101 |
| Purine nucleoside phosphorylase as a cytosolic arsenate reductase. | Toxicological sciences : an official journal of the Society of Toxicology 20021101 |
| Diagnosis and treatment of Wilson's disease. | Current neurology and neuroscience reports 20020701 |
| Arachidonic acid release and prostaglandin F2alpha formation induced by phenylarsine oxide in PC12 cells: possible involvement of secretory phospholipase A2 activity. | Biochemical pharmacology 20020701 |
| Role of ATP-sensitive potassium channels in prostaglandin-mediated gastroprotection in the rat. | The Journal of pharmacology and experimental therapeutics 20020601 |
| [Shotgun injury of head and neck: case report]. | No shinkei geka. Neurological surgery 20020501 |
| Oxidation of proximal protein sulfhydryls by phenanthraquinone, a component of diesel exhaust particles. | Chemical research in toxicology 20020401 |
| Mercuric oxide poisoning treated with whole-bowel irrigation and chelation therapy. | Annals of emergency medicine 20020301 |
| Effect of dithiol chelating agents on [3H]MK-801 and [3H]glutamate binding to synaptic plasma membranes. | Neurochemical research 20011201 |
| Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells. | Molecular and cellular biochemistry 20011001 |
| Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids. | The Biochemical journal 20010915 |
| Tributyltin interacts with mitochondria and induces cytochrome c release. | The Biochemical journal 20010601 |
| BAL modulates glutamate transport in synaptosomes and synaptic vesicles from rat brain. | Neuroreport 20010305 |
| The balance between CD45RChigh and CD45RClow CD4 T cells in rats is intrinsic to bone marrow-derived cells and is genetically controlled. | Journal of immunology (Baltimore, Md. : 1950) 20010301 |
| 2,3-Dimercaptopropanol inhibits Ca2+ transport in microsomes from brain but not from fast-skeletal muscle. | Neurochemical research 20010301 |
| Inhibition of human squalene monooxygenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls. | Journal of lipid research 20010201 |
| Surviving Wilson's disease. | Clinical medicine (London, England) 20010101 |
| Lead poisoning and chelation in a mother-neonate pair. | Journal of toxicology. Clinical toxicology 20010101 |
| Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase. | The Journal of biological chemistry 20001117 |
| Inhibition of tat-mediated HIV-1-LTR transactivation and virus replication by sulfhydryl compounds with chelating properties. | Anticancer research 20000101 |
| Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). | Molecular medicine (Cambridge, Mass.) 19951101 |
| Electrophile and antioxidant regulation of enzymes that detoxify carcinogens. | Proceedings of the National Academy of Sciences of the United States of America 19950912 |
| The effects of various kinase and phosphatase inhibitors on the transmission of the prolactin and extracellular matrix signals to rabbit alpha S1-casein and transferrin genes. | The international journal of biochemistry & cell biology 19950701 |
| Treatment of the neurologic manifestations of Wilson's disease. | Archives of neurology 19950401 |
| Phenylarsine oxide inhibits insulin-stimulated protein phosphatase 1 activity and GLUT-4 translocation. | The American journal of physiology 19940701 |
| Effects of phenylarsine oxide on insulin-stimulated system A amino acid uptake in skeletal muscle. | The American journal of physiology 19911001 |
| Arsenic poisoning in livestock. | Veterinary and human toxicology 19910601 |
| Uptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes. | The Biochemical journal 19900801 |
| 2,3 Dimercapto-1-propanol inhibits HIV-1 tat activity, viral production, and infectivity in vitro. | AIDS research and human retroviruses 19900701 |
| Rat anti-glomerular basement membrane antibodies in toxin-induced autoimmunity and in chronic graft-vs.-host reaction share recurrent idiotypes. | European journal of immunology 19900101 |
| Elevated antigalactosyl antibody titers reflect renal injury after gold or D-penicillamine in rheumatoid arthritis. | Clinical immunology and immunopathology 19860801 |
| Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes. | The Journal of biological chemistry 19850310 |
| A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis. | The Journal of rheumatology 19840601 |
| Inhibition of coupling factor B activity by cadmium ion, arsenite-2,3-dimercaptopropanol, and phenylarsine oxide, and preferential reactivation by dithiols. | The Journal of biological chemistry 19811110 |
| Chelation therapy in lead nephropathy. | Southern medical journal 19750801 |
| Penicillamine, a new oral therapy for Wilson's disease. | The American journal of medicine 19561001 |
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