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59-00-7

59-00-7 | XANTHURENIC ACID

CAS No: 59-00-7 Catalog No: AG003VC4 MDL No:MFCD00006754

Product Description

Catalog Number:
AG003VC4
Chemical Name:
XANTHURENIC ACID
CAS Number:
59-00-7
Molecular Formula:
C10H7NO4
Molecular Weight:
205.1669
MDL Number:
MFCD00006754
IUPAC Name:
8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
InChI:
InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
InChI Key:
FBZONXHGGPHHIY-UHFFFAOYSA-N
SMILES:
OC(=O)c1cc(O)c2c(n1)c(O)ccc2
EC Number:
200-410-1
UNII:
58LAB1BG8J
NSC Number:
401570

Properties

Complexity:
336  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
205.038g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
205.169g/mol
Monoisotopic Mass:
205.038g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
86.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.9  

Literature

Title Journal
Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. Journal of ethnopharmacology 20140528
Metabonomics evaluation of urine from rats administered with phorate under long-term and low-level exposure by ultra-performance liquid chromatography-mass spectrometry. Journal of applied toxicology : JAT 20140201
A urinary metabonomics study on biochemical changes in yeast-induced pyrexia rats: a new approach to elucidating the biochemical basis of the febrile response. Chemico-biological interactions 20130625
On the autofluorescence of fingermarks. Forensic science international 20121010
Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse. The Journal of biological chemistry 20120608
Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. Obstetrics and gynecology 20120601
Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity. Biology letters 20120423
NMR in metabolomics and natural products research: two sides of the same coin. Accounts of chemical research 20120221
A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development. PLoS pathogens 20120201
Ultrasensitive indicator-free and enhanced self-signal nanohybrid DNA sensing platform based on electrochemically grown poly-xanthurenic acid/Fe2O3 membranes. Biosensors & bioelectronics 20120115
Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA(2). Bioorganic & medicinal chemistry letters 20120115
Xanthurenic acid is an endogenous substrate for the silkworm cytosolic sulfotransferase, bmST1. Journal of insect physiology 20120101
Sexual development in Plasmodium: lessons from functional analyses. PLoS pathogens 20120101
The biology of sexual development of Plasmodium: the design and implementation of transmission-blocking strategies. Malaria journal 20120101
Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes. PloS one 20120101
The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal. PloS one 20120101
Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide. Alcohol and alcoholism (Oxford, Oxfordshire) 20111101
Tryptophan in alcoholism treatment I: kynurenine metabolites inhibit the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevate blood acetaldehyde concentration and induce aversion to alcohol. Alcohol and alcoholism (Oxford, Oxfordshire) 20111101
Simultaneous determination of tryptophan, kynurenine, kynurenic and xanthurenic acids in honey by liquid chromatography with diode array, fluorescence and tandem mass spectrometry detection. Journal of chromatography. A 20111021
UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. Journal of proteome research 20110902
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation. Cellular microbiology 20110701
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). Journal of proteome research 20110603
Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. Journal of pharmaceutical and biomedical analysis 20110601
Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito. Cellular microbiology 20110601
Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. Current neuropharmacology 20110601
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. PLoS pathogens 20110501
Quinolones: from antibiotics to autoinducers. FEMS microbiology reviews 20110301
Assessment of vitamin B(6) status in Korean patients with newly diagnosed type 2 diabetes. Nutrition research and practice 20110201
Identification of urinary biomarkers of colon inflammation in IL10-/- mice using Short-Column LCMS metabolomics. Journal of biomedicine & biotechnology 20110101
Metabolomic study of a rat fever model induced with 2,4-dinitrophenol and the therapeutic effects of a crude drug derived from Coptis chinensis. The American journal of Chinese medicine 20110101
Fluorescent derivatization of xanthurenic acid and nicotinic acid with horseradish peroxidase in the presence of excess hydrogen peroxide. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101
System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells. Journal of biomedical science 20110101
Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. BMC medical genetics 20110101
The Puf-family RNA-binding protein Puf2 controls sporozoite conversion to liver stages in the malaria parasite. PloS one 20110101
A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase. Neuropsychiatric disease and treatment 20110101
Optical effects of exposing intact human lenses to ultraviolet radiation and visible light. BMC ophthalmology 20110101
Optimized in vitro production of Plasmodium vivax ookinetes. The American journal of tropical medicine and hygiene 20101206
Dual role of the carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase: mitochondrial-targeting signal and enzymatic activity. Journal of biochemistry 20101201
Metabolomics identifies novel Hnf1alpha-dependent physiological pathways in vivo. Molecular endocrinology (Baltimore, Md.) 20101201
Effect of melatonin and caffeine interaction on caffeine induced oxidative stress and sleep disorders. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20101124
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission. Cell host & microbe 20101021
Neurotoxins: free radical mechanisms and melatonin protection. Current neuropharmacology 20100901
Photoinduced tautomeric transformations of xanthurenic acid. Physical chemistry chemical physics : PCCP 20100828
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicological sciences : an official journal of the Society of Toxicology 20100501
Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease. Journal of proteome research 20100405
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. PLoS neglected tropical diseases 20100401
Radioprotectors and mitigators of radiation-induced normal tissue injury. The oncologist 20100401
Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality. Molecular microbiology 20100301
Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. Clinica chimica acta; international journal of clinical chemistry 20100201
The coming-out of malaria gametocytes. Journal of biomedicine & biotechnology 20100101
A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies. Malaria journal 20100101
Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes. Malaria journal 20100101
An improved method for the in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes. Malaria journal 20100101
Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease. International journal of Alzheimer's disease 20100101
The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. PloS one 20100101
Apoptosis stalks Plasmodium falciparum maintained in continuous culture condition. Malaria journal 20100101
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. PloS one 20100101
Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. International journal of tryptophan research : IJTR 20100101
Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection. International journal of tryptophan research : IJTR 20100101
Characterization of Plasmodium falciparum calcium-dependent protein kinase 4. Parasitology international 20091201
Vital role for the Plasmodium actin capping protein (CP) beta-subunit in motility of malaria sporozoites. Molecular microbiology 20091201
Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei. Molecular and biochemical parasitology 20091201
Cloning and molecular characterization of tick kynurenine aminotransferase (HlKAT) from Haemaphysalis longicornis (Acari: Ixodidae). Parasitology research 20090901
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS pathogens 20090901
An essential role for the Plasmodium Nek-2 Nima-related protein kinase in the sexual development of malaria parasites. The Journal of biological chemistry 20090731
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20090501
Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease. Journal of proteome research 20090401
Combination of 1H nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry with pattern recognition techniques for evaluation of metabolic profile associated with albuminuria. Journal of proteome research 20090401
Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity. Experimental parasitology 20090201
Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. Molecular microbiology 20090101
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC medical genomics 20090101
Unlike the synchronous Plasmodium falciparum and P. chabaudi infection, the P. berghei and P. yoelii asynchronous infections are not affected by melatonin. International journal of general medicine 20090101
Photoactivity of kynurenine-derived UV filters. Journal of photochemistry and photobiology. B, Biology 20081211
Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry. Biomedical chromatography : BMC 20081201
Involvement of ST1B subfamily of cytosolic sulfotransferase in kynurenine metabolism to form natriuretic xanthurenic acid sulfate. The Journal of pharmacology and experimental therapeutics 20081201
Reverse genetics screen identifies six proteins important for malaria development in the mosquito. Molecular microbiology 20081001
Characterization of the 3-HKT gene in important malaria vectors in India, viz: Anopheles culicifacies and Anopheles stephensi (Diptera: Culicidae). Memorias do Instituto Oswaldo Cruz 20080901
Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. Molecular microbiology 20080701
Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. PLoS biology 20080601
Xanthurenic acid distribution, transport, accumulation and release in the rat brain. Journal of neurochemistry 20080501
Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. Fetal diagnosis and therapy 20080501
Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. The Journal of allergy and clinical immunology 20080401
Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance. PLoS pathogens 20080201
Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25. BMC microbiology 20080101
Genome-wide detection of serpentine receptor-like proteins in malaria parasites. PloS one 20080101
Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. PloS one 20080101
The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. Neuro endocrinology letters 20071201
Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development. PLoS pathogens 20071201
Minimum requirements for ookinete to oocyst transformation in Plasmodium. International journal for parasitology 20070901
Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. Molecular endocrinology (Baltimore, Md.) 20070901
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase. Journal of inherited metabolic disease 20070401
The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. Journal of insect physiology 20070301
An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. BMC genomics 20070101
Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold. Biology direct 20070101
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. The Journal of biological chemistry 20061201
Prooxidant action of xanthurenic acid and quinoline compounds: role of transition metals in the generation of reactive oxygen species and enhanced formation of 8-hydroxy-2'-deoxyguanosine in DNA. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060801
The effects of blood feeding and exogenous supply of tryptophan on the quantities of xanthurenic acid in the salivary glands of Anopheles stephensi (Diptera: Culicidae). Biochemical and biophysical research communications 20060324
Plasmodium development in white-eye (kh(w)) and transformed strains (kh43) of Aedes aegypti (Diptera: Culicidae). Journal of medical entomology 20060301
Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behavioral and brain functions : BBF 20060101
[Metabolite fingerprint and biomarkers identification of rat urine after dosed with ginsenoside Rg3 based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)]. Se pu = Chinese journal of chromatography 20060101
The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like beta-grasp domains. Genome biology 20060101
Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. American journal of physiology. Cell physiology 20051101
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase. The FEBS journal 20051101
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach. Toxicology 20050214
Separation and determination of L-tryptophan and its metabolites by capillary micellar electrokinetic chromatography with amperometric detection. Electrophoresis 20050201
Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20050101
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis research & therapy 20050101
Effects of some naturally occurring iron ion chelators on in vitro superoxide radical formation. Biological trace element research 20050101
Synthesis and iron-binding properties of quinolobactin, a siderophore from a pyoverdine-deficient Pseudomonas fluorescens. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20041201
Tracheal tone and the role of ionotropic glutamate receptors in the nucleus ambiguus. Brain research 20040917
Comment on 'The photosensitiser xanthurenic acid is not present in normal human lenses' by P.G. Hains et al. [Exp. Eye Res. 77 (2003) 547-553]. Experimental eye research 20040901
A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. The Analyst 20040601
Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics. Journal of pharmaceutical and biomedical analysis 20040528
Gamete interruptus; a novel calcium-dependent kinase is essential for malaria sexual reproduction. Cell 20040514
Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite. Cell 20040514
The Pseudomonas siderophore quinolobactin is synthesized from xanthurenic acid, an intermediate of the kynurenine pathway. Molecular microbiology 20040401
Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function. BMC cell biology 20040101
The photosensitiser xanthurenic acid is not present in normal human lenses. Experimental eye research 20031101
Abnormal signalling of 14-3-3 proteins in cells with accumulated xanthurenic acid. Biochemical and biophysical research communications 20031017
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions. Journal of pineal research 20030501
Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis. Malaria journal 20030101
Neurokynurenines--seizures or/and anxiety in children with epilepsy? Advances in experimental medicine and biology 20030101
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. Advances in experimental medicine and biology 20030101
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. Advances in experimental medicine and biology 20030101
Increase in conversion of tryptophan to niacin in pregnant rats. Advances in experimental medicine and biology 20030101
The effects of phthalate esters on the tryptophan-niacin metabolism. Advances in experimental medicine and biology 20030101
Photochemical properties of kynurenine pathway metabolites and indoleamines. Advances in experimental medicine and biology 20030101
Formation of kynurenic and xanthurenic acids from kynurenine and 3-hydroxykynurenine in the dinoflagellate Lingulodinium polyedrum: role of a novel, oxidative pathway. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021101
cDNA cloning, functional expression and characterization of kynurenine 3-hydroxylase of Anopheles stephensi (Diptera: Culicidae). Insect molecular biology 20021001
Role of xanthurenic acid 8-O-beta-D-glucoside, a novel fluorophore that accumulates in the brunescent human eye lens. Photochemistry and photobiology 20020901
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity. Bioscience, biotechnology, and biochemistry 20020701
Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. Journal of medicinal chemistry 20020523
3-Hydroxykynurenine transaminase identity with alanine glyoxylate transaminase. A probable detoxification protein in Aedes aegypti. The Journal of biological chemistry 20020503
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure. Nephron 20020301
Effect of pyruvate on the function of stallion spermatozoa stored for up to 48 hours. Journal of animal science 20020101
Lens epithelial cell apoptosis and intracellular Ca2+ increase in the presence of xanthurenic acid. BMC ophthalmology 20020101
Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. The Biochemical journal 20011215
Kynurenine and its metabolites in the rat with experimental renal insufficiency. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201
Ocular phototoxicity. Journal of photochemistry and photobiology. B, Biology 20011115
Photooxidation of lens proteins with xanthurenic acid: a putative chromophore for cataractogenesis. Photochemistry and photobiology 20011101
Characterization and identification of exflagellation-inducing factor in the salivary gland of Anopheles stephensi (Diptera: Culicidae). Biochemical and biophysical research communications 20011005
The gametocyte-activating factor xanthurenic acid stimulates an increase in membrane-associated guanylyl cyclase activity in the human malaria parasite Plasmodium falciparum. Molecular microbiology 20011001
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats. Bioscience, biotechnology, and biochemistry 20011001
Toxicologic significance of the hyperglycemia caused by organophosphorous insecticides. Bulletin of environmental contamination and toxicology 20011001
Identification of a novel fluorophore, xanthurenic acid 8- O -beta-D-glucoside in human brunescent cataract. Experimental eye research 20011001
Effect of xanthurenic acid on infectivity of Plasmodium falciparum to Anopheles stephensi. International journal for parasitology 20010801
Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito. Molecular and biochemical parasitology 20010801
Development of a method for the in vitro production of Plasmodium vivax ookinetes. The Journal of parasitology 20010801
Xanthurenic acid inhibits metal ion-induced lipid peroxidation and protects NADP-isocitrate dehydrogenase from oxidative inactivation. Journal of nutritional science and vitaminology 20010801
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. Bioscience, biotechnology, and biochemistry 20010601
[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets. The British journal of nutrition 20010101
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown. BMC physiology 20010101
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients. International urology and nephrology 20010101
Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids. Journal of neural transmission 19830101

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