200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 58-46-8
58-46-8 | Tetrabenazine
CAS No: 58-46-8 Catalog No: AG003UMF MDL No:MFCD00042740
Product Description
Catalog Number:
AG003UMF
Chemical Name:
Tetrabenazine
CAS Number:
58-46-8
Molecular Formula:
C19H27NO3
Molecular Weight:
317.4226
MDL Number:
MFCD00042740
IUPAC Name:
9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
InChI:
InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3
InChI Key:
MKJIEFSOBYUXJB-UHFFFAOYSA-N
SMILES:
COc1cc2c(cc1OC)CCN1C2CC(=O)C(C1)CC(C)C
Properties
Complexity:
425
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
317.199g/mol
Formal Charge:
0
Heavy Atom Count:
23
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
317.429g/mol
Monoisotopic Mass:
317.199g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
38.8A^2
Undefined Atom Stereocenter Count:
2
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9
Literature
| Title | Journal |
|---|---|
| Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. | The Journal of pharmacology and experimental therapeutics 20170601 |
| Randomized controlled trial of deutetrabenazine for tardive dyskinesia: The ARM-TD study. | Neurology 20170523 |
| Dopamine depleters in the treatment of hyperkinetic movement disorders. | Expert opinion on pharmacotherapy 20161201 |
| Deutetrabenazine for Treatment of Chorea in Huntington Disease. | JAMA 20160705 |
| Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial. | JAMA 20160705 |
| NBI-98854, a selective monoamine transport inhibitor for the treatment of tardive dyskinesia: A randomized, double-blind, placebo-controlled study. | Movement disorders : official journal of the Movement Disorder Society 20151001 |
| Neuroleptic malignant syndrome induced by combination therapy with tetrabenazine and tiapride in a Japanese patient with Huntington's disease at the terminal stage of recurrent breast cancer. | Internal medicine (Tokyo, Japan) 20140101 |
| Benign hereditary chorea: phenotype, prognosis, therapeutic outcome and long term follow-up in a large series with new mutations in the TITF1/NKX2-1 gene. | Journal of neurology, neurosurgery, and psychiatry 20121001 |
| Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. | Molecular endocrinology (Baltimore, Md.) 20121001 |
| Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([¹⁸F]AV-133) in a MPTP-lesioned PD mouse model. | Synapse (New York, N.Y.) 20120901 |
| A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport. | Journal of neuroscience methods 20120815 |
| Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology. | Neurology 20120807 |
| Neuroferritinopathy: update on clinical features and pathogenesis. | Current drug targets 20120801 |
| Heterogeneity of cholinergic denervation in Parkinson's disease without dementia. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120801 |
| Effect of tetrabenazine on computerized dynamic posturography in Huntington disease patients. | Parkinsonism & related disorders 20120801 |
| Management of status dystonicus in children. Cases report and review. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120701 |
| Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature. | Clinical therapeutics 20120701 |
| Comprehensive treatment of Huntington disease and other choreic disorders. | Cleveland Clinic journal of medicine 20120701 |
| In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120601 |
| Simple, rapid and reliable preparation of [¹¹C]-(+)-α-DTBZ of high quality for routine applications. | Molecules (Basel, Switzerland) 20120601 |
| An evidence-based approach in the treatment of Huntington's disease. | Parkinsonism & related disorders 20120501 |
| DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function. | Neurobiology of aging 20120401 |
| Rapid improvement of tardive dyskinesia with tetrabenazine, clonazepam and clozapine combined: a naturalistic long-term follow-up study. | Journal of neurology 20120401 |
| Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens. | Journal of neurochemistry 20120401 |
| Canadian guidelines for the evidence-based treatment of tic disorders: pharmacotherapy. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20120301 |
| Tetrabenazine augmentation in treatment-resistant schizophrenia: a 12-week, double-blind, placebo-controlled trial. | Journal of clinical psychopharmacology 20120201 |
| In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in cocaine abusers. | The American journal of psychiatry 20120101 |
| The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease. | Parkinson's disease 20120101 |
| Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. | Neuro-degenerative diseases 20120101 |
| Genetic mapping and exome sequencing identify variants associated with five novel diseases. | PloS one 20120101 |
| Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
| Anesthetic management of deep brain stimulator implantation in Meige's syndrome. | Journal of anaesthesiology, clinical pharmacology 20120101 |
| No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease. | PloS one 20120101 |
| Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview. | International journal of general medicine 20120101 |
| Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. | Substance abuse treatment, prevention, and policy 20120101 |
| Update on the role of antipsychotics in the treatment of Tourette syndrome. | Neuropsychiatric disease and treatment 20120101 |
| PET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133). | PloS one 20120101 |
| Hyperosmolar non-ketotic hyperglycaemia: an important and reversible cause of acute bilateral ballismus. | BMJ case reports 20120101 |
| Tetrabenazine treatment for stereotypies and tics associated with dementia. | The Journal of neuropsychiatry and clinical neurosciences 20120101 |
| Sensory trick with metoclopramide-associated tardive tremor. | BMJ case reports 20120101 |
| Improved working memory but no effect on striatal vesicular monoamine transporter type 2 after omega-3 polyunsaturated fatty acid supplementation. | PloS one 20120101 |
| A concise synthesis of tetrabenazine: an intramolecular aza-Prins-type cyclization via oxidative C-H activation. | Organic letters 20111216 |
| Tardive syndrome and Parkinson's disease responsive to concomitant tetrabenazine and levodopa therapy. | Parkinsonism & related disorders 20111201 |
| Postthalamic stroke dystonic choreoathetosis responsive to tetrabenazine. | The Annals of pharmacotherapy 20111201 |
| Tetrabenazine: for chorea associated with Huntington's disease. | CNS drugs 20111201 |
| How best to address these common movement disorders. | The Journal of family practice 20111201 |
| Use of Tetrabenazine in Huntington Disease Patients on Antidepressants or with Advanced Disease: Results from the TETRA-HD Study. | PLoS currents 20111113 |
| Optimal scanning time window for 18F-FP-(+)-DTBZ (18F-AV-133) summed uptake measurements. | Nuclear medicine and biology 20111101 |
| Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders. | Expert review of neurotherapeutics 20111101 |
| Determination of the penetration of 9-fluoropropyl-(+)-dihydrotetrabenazine across the blood-brain barrier in rats by microdialysis combined with liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111015 |
| An International Survey-based Algorithm for the Pharmacologic Treatment of Chorea in Huntington's Disease. | PLoS currents 20111011 |
| Sigma receptor binding of tetrabenazine series tracers targeting VMAT2 in rat pancreas. | Nuclear medicine and biology 20111001 |
| Altered affinity of the platelet vesicular monoamine transporter 2 to dihydrotetrabenazine in children with major depression. | Journal of neural transmission (Vienna, Austria : 1996) 20110901 |
| Tetrabenazine inhibition of monoamine uptake and methamphetamine behavioral effects: locomotor activity, drug discrimination and self-administration. | Neuropharmacology 20110901 |
| Therapeutic advances in the management of Huntington's disease. | The Yale journal of biology and medicine 20110901 |
| Sex differences in methamphetamine toxicity in mice: effect on brain dopamine signaling pathways. | Psychoneuroendocrinology 20110801 |
| Post pump chorea in a 77-year-old male. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110801 |
| Leucoaraiosis, nigrostriatal denervation and motor symptoms in Parkinson's disease. | Brain : a journal of neurology 20110801 |
| Platelet vesicular monoamine transporter 2 density in the disruptive behavior disorders. | Journal of child and adolescent psychopharmacology 20110801 |
| Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry. | Medicinal research reviews 20110701 |
| In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease. | Archives of neurology 20110701 |
| Tardive dyskinesia. | Current treatment options in neurology 20110601 |
| Synthesis and biological evaluation of 3-alkyl-dihydrotetrabenazine derivatives as vesicular monoamine transporter-2 (VMAT2) ligands. | Bioorganic & medicinal chemistry letters 20110601 |
| Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography. | Brain : a journal of neurology 20110601 |
| Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. | Annals of neurology 20110501 |
| Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors. | European journal of medicinal chemistry 20110501 |
| Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY. | PLoS currents 20110413 |
| European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. | European child & adolescent psychiatry 20110401 |
| Tetrabenazine for the treatment of tardive dyskinesia. | The Annals of pharmacotherapy 20110401 |
| Study the effect of a pseudo-carrier on pharmacokinetics of 9-fluoropropyl-(+)-dihydrotetrabenazine in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110301 |
| Differential electrophysiological changes in striatal output neurons in Huntington's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110126 |
| Tardive dyskinesia and other movement disorders secondary to aripiprazole. | Movement disorders : official journal of the Movement Disorder Society 20110101 |
| Huntington's disease: From molecular basis to therapeutic advances. | The international journal of biochemistry & cell biology 20110101 |
| Oral pharmacological treatment of X-linked dystonia parkinsonism: successes and failures. | The International journal of neuroscience 20110101 |
| Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease. | PloS one 20110101 |
| Management of Huntington's disease: role of tetrabenazine. | Therapeutics and clinical risk management 20110101 |
| Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice. | PloS one 20110101 |
| Hemiballismus. | Handbook of clinical neurology 20110101 |
| Hyperglycemic nonketotic states and other metabolic imbalances. | Handbook of clinical neurology 20110101 |
| Nonprimary dystonias. | Handbook of clinical neurology 20110101 |
| Mcleod syndrome: Report of an Indian family with phenotypic heterogeneity. | Annals of Indian Academy of Neurology 20110101 |
| Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review. | Journal of pharmacy & bioallied sciences 20110101 |
| Vesicular monoamine transporter-1 (VMAT-1) mRNA and immunoreactive proteins in mouse brain. | Neuro endocrinology letters 20110101 |
| Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease. | Frontiers in systems neuroscience 20110101 |
| Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease. | Neurology research international 20110101 |
| Tardive Meige's syndrome associated with olanzapine. | Annals of Indian Academy of Neurology 20110101 |
| Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease. | Molecular neurodegeneration 20110101 |
| Molecular imaging: a promising tool to monitor islet transplantation. | Journal of transplantation 20110101 |
| Quadriparesis and dysarthria due to tetrabenazine therapy in a child with rheumatic chorea. | Indian journal of pharmacology 20110101 |
| Long-stay psychiatric patients: a prospective study revealing persistent antipsychotic-induced movement disorder. | PloS one 20110101 |
| Neuroacanthocytosis syndromes. | Orphanet journal of rare diseases 20110101 |
| N-methyl D-aspartate receptor encephalitis: A new addition to the spectrum of autoimmune encephalitis. | Annals of Indian Academy of Neurology 20110101 |
| Moving forward: advances in the treatment of movement disorders with deep brain stimulation. | Frontiers in integrative neuroscience 20110101 |
| Dantrolene is neuroprotective in Huntington's disease transgenic mouse model. | Molecular neurodegeneration 20110101 |
| [Medical aspects of the medical treatment in dystonia]. | Bulletin de l'Academie nationale de medecine 20110101 |
| The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats. | The Journal of pharmacology and experimental therapeutics 20101201 |
| Brain serotonergic circuitries. | Dialogues in clinical neuroscience 20101201 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Rat pancreas uptake of [11C]dihydrotetrabenazine stereoisomers. | Nuclear medicine and biology 20101101 |
| Dramatic response of facial stereotype/tic to tetrabenazine in the first reported cases of neuroferritinopathy in the United States. | Movement disorders : official journal of the Movement Disorder Society 20101030 |
| The effect of chronic methylphenidate administration on presynaptic dopaminergic parameters in a rat model for ADHD. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20101001 |
| Effect of tetrabenazine use on restless legs syndrome. | Sleep medicine 20101001 |
| Reserpine causes biphasic nociceptive sensitivity alteration in conjunction with brain biogenic amine tones in rats. | Neuroscience 20100915 |
| Whole-body biodistribution and radiation dosimetry of 18F-FP-(+)-DTBZ (18F-AV-133): a novel vesicular monoamine transporter 2 imaging agent. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
| 11C-dihydrotetrabenazine beta-cell imaging. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
| Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
| Parkinson's disease and other movement disorders. | The American journal of geriatric pharmacotherapy 20100801 |
| Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. | The American journal of geriatric pharmacotherapy 20100801 |
| Drug safety monitoring in patients of movement disorders of a tertiary care hospital. | Indian journal of pharmacology 20100801 |
| Tourette's Disorder. | Current treatment options in neurology 20100701 |
| Coexisting huntingtin and SCA8 repeat expansion: case report of a severe complex neurodegenerative syndrome. | Journal of the neurological sciences 20100615 |
| A case of secondary dystonia responding to levodopa. | Journal of child neurology 20100601 |
| Influence of a low dose of amphetamine on vesicular monoamine transporter binding: a PET (+)[11C]DTBZ study in humans. | Synapse (New York, N.Y.) 20100601 |
| Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An (18)F-DOPA and (11)C-DTBZ PET study. | Neurobiology of disease 20100601 |
| Role of tetrabenazine for Huntington's disease-associated chorea. | The Annals of pharmacotherapy 20100601 |
| A case of PANDAS treated with tetrabenazine and tonsillectomy. | Journal of child neurology 20100501 |
| Binding characteristics of 9-fluoropropyl-(+)-dihydrotetrabenzazine (AV-133) to the vesicular monoamine transporter type 2 in rats. | Nuclear medicine and biology 20100501 |
| In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease. | Nuclear medicine and biology 20100501 |
| In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass. | Nuclear medicine and biology 20100401 |
| Comparing fludeoxyglucose F18-PET assessment of regional cerebral glucose metabolism and [11C]dihydrotetrabenazine-PET in evaluation of early dementia and mild cognitive impairment. | Archives of neurology 20100401 |
| Advances in the pharmacological management of Huntington's disease. | Drugs 20100326 |
| Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter. | The Journal of biological chemistry 20100212 |
| The utility of [(11)C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal-jejunal bypass. | Surgery 20100201 |
| Dopamine transporter PET in normal aging: dopamine transporter decline and its possible role in preservation of motor function. | Synapse (New York, N.Y.) 20100201 |
| Dysregulation of intracellular dopamine stores revealed in the R6/2 mouse striatum. | Journal of neurochemistry 20100201 |
| In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100201 |
| An improved radiosynthesis of [18F]AV-133: a PET imaging agent for vesicular monoamine transporter 2. | Nuclear medicine and biology 20100201 |
| Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters. | Bioorganic & medicinal chemistry 20100115 |
| In vivo [11C]dihydrotetrabenazine binding in rat striatum: sensitivity to dopamine concentrations. | Nuclear medicine and biology 20100101 |
| Changes in clinical trials methodology over time: a systematic review of six decades of research in psychopharmacology. | PloS one 20100101 |
| Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. | PloS one 20100101 |
| Tetrabenazine is neuroprotective in Huntington's disease mice. | Molecular neurodegeneration 20100101 |
| Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease. | Neuropsychiatric disease and treatment 20100101 |
| Extrastriatal dopaminergic circuits of the Basal Ganglia. | Frontiers in neuroanatomy 20100101 |
| Huntington's disease: a clinical review. | Orphanet journal of rare diseases 20100101 |
| Hot tongue on FDG PET scan in a patient of Hodgkin's lymphoma undergoing antipsychotic treatment. | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India 20100101 |
| Dysphagia due to tardive dyskinesia. | Industrial psychiatry journal 20100101 |
| Oro-mandibular dystonia. | National journal of maxillofacial surgery 20100101 |
| Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2). | Journal of medicinal chemistry 20091210 |
| Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter. | Journal of neural transmission (Vienna, Austria : 1996) 20091201 |
| Tetrabenazine. | Expert opinion on pharmacotherapy 20091201 |
| MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. | Neurotoxicology 20091101 |
| Synthesis and evaluation of 2-amino-dihydrotetrabenzine derivatives as probes for imaging vesicular monoamine transporter-2. | Bioorganic & medicinal chemistry letters 20090901 |
| Treatment of hyperkinetic movement disorders. | The Lancet. Neurology 20090901 |
| Treating complex movement disorders in children with cerebral palsy. | The Ulster medical journal 20090901 |
| Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues. | The Journal of organic chemistry 20090821 |
| New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification. | NeuroImage 20090815 |
| Pelvic dyskinesia with an outstanding response to tetrabenazine. | Progress in neuro-psychopharmacology & biological psychiatry 20090801 |
| Visualizing vesicular dopamine dynamics in Parkinson's disease. | Synapse (New York, N.Y.) 20090801 |
| [Choreoathetosis after Herpes simplex encephalitis]. | Anales de pediatria (Barcelona, Spain : 2003) 20090801 |
| Therapeutic interventions for symptomatic treatment in Huntington's disease. | The Cochrane database of systematic reviews 20090708 |
| Signal separation and parameter estimation in noninvasive dual-tracer PET scans using reference-region approaches. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090701 |
| Noninvasive imaging of pancreatic beta cells. | Nature reviews. Endocrinology 20090701 |
| Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701 |
| Treatment of chorea associated with Huntington's disease: focus on tetrabenazine. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20090701 |
| Wilson's disease--a rare psychiatric presentation. | Journal of the Indian Medical Association 20090701 |
| Measurement of plasmalemmal dopamine transport, vesicular dopamine transport, and K(+)-stimulated dopamine release in frozen rat brain tissue. | Journal of neuroscience methods 20090615 |
| New drugs 09, part 2. | Nursing 20090601 |
| Aplysinopsins--marine indole alkaloids: chemistry, bioactivity and ecological significance. | Marine drugs 20090601 |
| Asymmetric synthesis of tetrabenazine and dihydrotetrabenazine. | The Journal of organic chemistry 20090515 |
| Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes. | Parkinsonism & related disorders 20090501 |
| Paroxysmal dyskinesias. | Current treatment options in neurology 20090501 |
| [Therapeutic use of tetrabenazine]. | Revista de neurologia 20090501 |
| Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome. | Neurology 20090421 |
| PET demonstrates reduced dopamine transporter expression in PD with dyskinesias. | Neurology 20090407 |
| Dyskinesia in Parkinson disease: back for the future? | Neurology 20090407 |
| Pancreatic imaging with 11C-dihydrotetrabenazine PET: a perspective. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301 |
| 11C-dihydrotetrabenazine PET of the pancreas in subjects with long-standing type 1 diabetes and in healthy controls. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301 |
| Tetrabenazine (Xenazine) for Huntington's chorea. | The Medical letter on drugs and therapeutics 20090126 |
| Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine. | Movement disorders : official journal of the Movement Disorder Society 20090115 |
| Tetrabenazine. | Nature reviews. Drug discovery 20090101 |
| Hypertensive crisis and cheese. | Indian journal of psychiatry 20090101 |
| Treatment of Tardive Dyskinesia by tetrabenazine, clonazepam and vitamin E. | Indian journal of psychiatry 20090101 |
| Chorea-ballismus in acute non-ketotic hyperglycaemia. | Functional neurology 20090101 |
| Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators. | BMC neurology 20090101 |
| Amoxapine-induced tardive dyskinesia. | Indian journal of psychiatry 20090101 |
| Movement disorder: a manifestation of HIV and its response to therapy. | Neurology India 20090101 |
| Olanzapine induced tardive dystonia in case of adolescent bipolar disorder. | Journal of pediatric neurosciences 20090101 |
| Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism. | Journal of neurochemistry 20081201 |
| Tetrabenazine (Xenazine), An FDA-Approved Treatment Option For Huntington's Disease-Related Chorea. | P & T : a peer-reviewed journal for formulary management 20081201 |
| Dopamine modulating drugs influence striatal (+)-[11C]DTBZ binding in rats: VMAT2 binding is sensitive to changes in vesicular dopamine concentration. | Synapse (New York, N.Y.) 20081101 |
| Increased beta activity in dystonia patients after drug-induced dopamine deficiency. | Experimental neurology 20081101 |
| In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine. | Nuclear medicine and biology 20081101 |
| Gene therapy offers HD patients relief from some symptoms. Tetrabenazine inhibits the transport of a molecule called vesicular monoamine transporter type 2 or VMAT2. | Managed care (Langhorne, Pa.) 20081101 |
| Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924 |
| Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists. | Bioorganic & medicinal chemistry letters 20080915 |
| Anterocollis: clinical features and treatment options. | Medical science monitor : international medical journal of experimental and clinical research 20080901 |
| Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. | Current neuropharmacology 20080901 |
| Psychopharmacology of tic disorders. | Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent 20080801 |
| In vivo imaging of beta-cell mass in rats using 18F-FP-(+)-DTBZ: a potential PET ligand for studying diabetes mellitus. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080701 |
| Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine. | The Journal of endocrinology 20080701 |
| Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine. | Journal of neurochemistry 20080601 |
| Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. | Journal of neurochemistry 20080601 |
| Camptocormia: a rare axial myopathy disease. | Clinics (Sao Paulo, Brazil) 20080601 |
| Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography. | Psychiatry research 20080530 |
| Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. | Human molecular genetics 20080515 |
| Treatment of tardive dyskinesia with levetiracetam in a transplant patient. | Acta neurologica Scandinavica 20080501 |
| [Severe generalized dystonia due to postradiotherapy cerebral calcifications]. | Revue neurologique 20080501 |
| VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. | Journal of neurochemistry 20080401 |
| Whole body [11C]-dihydrotetrabenazine imaging of baboons: biodistribution and human radiation dosimetry estimates. | European journal of nuclear medicine and molecular imaging 20080401 |
| Comparison of weight gain in treatments for Tourette syndrome: tetrabenazine versus neuroleptic drugs. | Journal of child neurology 20080401 |
| Expression and function of the rat vesicular monoamine transporter 2. | American journal of physiology. Cell physiology 20080401 |
| Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease. | Annals of neurology 20080301 |
| [A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508]. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080301 |
| Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study. | Journal of medicinal chemistry 20080227 |
| [Quick and simple synthesis of (11)C-(+)-alpha-dihydrotetrabenazine to be used as a PET radioligand of vesicular monoamine transporters]. | Revista espanola de medicina nuclear 20080101 |
| [Use of 11C-(+)-alpha -dihydrotetrabenazine for the assessment of dopaminergic innervation in animal models of Parkinson's disease]. | Revista espanola de medicina nuclear 20080101 |
| A study of chorea after tetrabenazine withdrawal in patients with Huntington disease. | Clinical neuropharmacology 20080101 |
| Tourette's syndrome and role of tetrabenazine: review and personal experience. | Clinical drug investigation 20080101 |
| Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20080101 |
| New drugs: Clevidipine butyrate, difluprednate, and tetrabenazine. | Journal of the American Pharmacists Association : JAPhA 20080101 |
| The long-term effect of tetrabenazine in the management of Huntington disease. | Clinical neuropharmacology 20080101 |
| Normal dopaminergic nigrostriatal innervation in SPG3A hereditary spastic paraplegia. | Journal of neurogenetics 20080101 |
| Identification of the substrate binding region of vesicular monoamine transporter-2 (VMAT-2) using iodoaminoflisopolol as a novel photoprobe. | Molecular pharmacology 20071201 |
| Neurotransmitter depleter tetrabenazine; potential candidate for schizophrenia treatment? | Schizophrenia research 20071101 |
| PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071001 |
| Tetrabenazine in the treatment of Huntington's disease. | Neuropsychiatric disease and treatment 20071001 |
| Drug-induced tardive motor syndromes. | Psychiatrike = Psychiatriki 20071001 |
| Specific derivatization of the vesicle monoamine transporter with novel carrier-free radioiodinated reserpine and tetrabenazine photoaffinity labels. | Analytical biochemistry 20070801 |
| Dopaminergic signaling and striatal neurodegeneration in Huntington's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070725 |
| Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP. | Toxicology letters 20070710 |
| In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070701 |
| Reduced platelet vesicular monoamine transporter density in Tourette's syndrome pediatric male patients. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070701 |
| Antidepressant activity of some Hypericum reflexum L. fil. extracts in the forced swimming test in mice. | Journal of ethnopharmacology 20070530 |
| Vesicular monoamine transporter 1 mediates dopamine secretion in rat proximal tubular cells. | American journal of physiology. Renal physiology 20070501 |
| Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2. | Bioorganic & medicinal chemistry 20070415 |
| Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain. | Nuclear medicine and biology 20070401 |
| Characterization of optically resolved 9-fluoropropyl-dihydrotetrabenazine as a potential PET imaging agent targeting vesicular monoamine transporters. | Nuclear medicine and biology 20070401 |
| Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. | Neurology 20070306 |
| A systematic review of the treatment studies in Huntington's disease since 1990. | Expert opinion on pharmacotherapy 20070201 |
| Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. | Movement disorders : official journal of the Movement Disorder Society 20070115 |
| Short-term effects of tetrabenazine on chorea associated with Huntington's disease. | Movement disorders : official journal of the Movement Disorder Society 20070101 |
| Olanzapine-induced tardive dystonia successfully treated by tetrabenazine. | The Journal of neuropsychiatry and clinical neurosciences 20070101 |
| Parkinsonism and tremor disorders. A clinical approach. | The Libyan journal of medicine 20070101 |
| Exocytotic release of dopamine in ventral tegmental area slices from C57BL/6 and dopamine transporter knockout mice. | Neurochemistry international 20061201 |
| Vesicular monoamine transporter 2: role as a novel target for drug development. | The AAPS journal 20061201 |
| Therapeutic Strategies in Huntington's Disease. | Journal of clinical neurology (Seoul, Korea) 20061201 |
| Tetrabenazine therapy of pediatric hyperkinetic movement disorders. | Movement disorders : official journal of the Movement Disorder Society 20061101 |
| Tetrabenazine for hyperglycemic-induced hemichorea-hemiballismus. | Movement disorders : official journal of the Movement Disorder Society 20061101 |
| [The study and treatment of dystonias in childhood]. | Revista de neurologia 20061010 |
| Interaction of amphetamines and related compounds at the vesicular monoamine transporter. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Is tetrabenazine safe and effective for suppressing chorea in Huntington's disease? | Nature clinical practice. Neurology 20061001 |
| Visualizing pancreatic beta-cell mass with [11C]DTBZ. | Nuclear medicine and biology 20061001 |
| Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060901 |
| Fluoroalkyl derivatives of dihydrotetrabenazine as positron emission tomography imaging agents targeting vesicular monoamine transporters. | Nuclear medicine and biology 20060801 |
| Measurement of kinetically resolved vesicular dopamine uptake and efflux using rotating disk electrode voltammetry. | Journal of neuroscience methods 20060715 |
| Tetrabenazine versus placebo for chorea in Huntington's disease. | Current neurology and neuroscience reports 20060701 |
| Partial depletion of dopamine in substantia nigra impairs motor performance without altering striatal dopamine neurotransmission. | The European journal of neuroscience 20060701 |
| Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model. | The Journal of clinical investigation 20060601 |
| Huntington's Disease. | Current treatment options in neurology 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. | Neurology 20060214 |
| A blessing in disguise: resolution of tardive dyskinesia with development of cervical myelitis. | Movement disorders : official journal of the Movement Disorder Society 20060101 |
| Tetrabenazine in the treatment of hyperkinetic movement disorders. | Expert review of neurotherapeutics 20060101 |
| Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series. | BMC neurology 20060101 |
| Pharmacological management of Huntington's disease: an evidence-based review. | Current pharmaceutical design 20060101 |
| Evaluation of the integrity of the dopamine system in a rodent model of Parkinson's disease: small animal positron emission tomography compared to behavioral assessment and autoradiography. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20060101 |
| Is history of depression a contraindication to treatment with tetrabenazine? | Clinical neuropharmacology 20060101 |
| Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population. | Behavioral and brain functions : BBF 20060101 |
| Eating dysfunction associated with oromandibular dystonia: clinical characteristics and treatment considerations. | Head & face medicine 20060101 |
| PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation. | Brain : a journal of neurology 20051201 |
| Treatment with the new antipsychotic sertindole for late-occurring undesirable movement effects. | International clinical psychopharmacology 20051101 |
| Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia. | Psychiatry research 20050915 |
| Management of the extrapyramidal syndrome in chronic acquired hepatocerebral degeneration (CAHD). | Movement disorders : official journal of the Movement Disorder Society 20050801 |
| The influence of measurement uncertainties on the evaluation of the distribution volume ratio and binding potential in rat studies on a microPET R4: a phantom study. | Physics in medicine and biology 20050621 |
| 11C-DTBZ and 18F-FDG PET measures in differentiating dementias. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050601 |
| Emerging drugs in Tourette syndrome. | Expert opinion on emerging drugs 20050501 |
| Antidepressant properties of some Hypericum canariense L. and Hypericum glandulosum Ait. extracts in the forced swimming test in mice. | Journal of ethnopharmacology 20050321 |
| Decreased platelet vesicular monoamine transporter density in children and adolescents with attention deficit/hyperactivity disorder. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301 |
| Decreased platelet vesicular monoamine transporter density in habitual smokers. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301 |
| The role of radiotracer imaging in Parkinson disease. | Neurology 20050125 |
| Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis. | Archives of neurology 20041201 |
| Identification of tissue-restricted transcripts in human islets. | Endocrinology 20041001 |
| Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters. | The Journal of pharmacology and experimental therapeutics 20040901 |
| The effect of rare human sequence variants on the function of vesicular monoamine transporter 2. | Pharmacogenetics 20040901 |
| Differential effects of scopolamine on in vivo binding of dopamine transporter and vesicular monoamine transporter radioligands in rat brain. | Experimental neurology 20040801 |
| PET studies and physiopathology of motor fluctuations in Parkinson's disease. | Brain : a journal of neurology 20040801 |
| [Movement disorders in childhood: therapeutic update]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20040801 |
| Adrafinil-induced orofacial dyskinesia. | Movement disorders : official journal of the Movement Disorder Society 20040801 |
| Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040701 |
| Long-term reproducibility of in vivo measures of specific binding of radioligands in rat brain. | Nuclear medicine and biology 20040701 |
| Striatal monoamine terminals in Lewy body dementia and Alzheimer's disease. | Annals of neurology 20040601 |
| Electrochemical monitoring of transport by a vesicular monoamine transporter expressed in Xenopus oocytes. | Journal of neuroscience methods 20040215 |
| Dopamine transmission in DYT1 dystonia. | Advances in neurology 20040101 |
| Behavioural effects of thieno and pyrazolo [2,1] benzothiazepine derivatives in mice. | Arzneimittel-Forschung 20040101 |
| Tetrabenazine treatment in movement disorders. | Clinical neuropharmacology 20040101 |
| [11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease. | Brain : a journal of neurology 20031201 |
| Raclopride studies of dopamine release: dependence on presynaptic integrity. | Biological psychiatry 20031201 |
| Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. | Brain research 20031107 |
| Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease. | Experimental neurology 20031101 |
| Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001 |
| Endogenous 5-HT, released by MDMA through serotonin transporter- and secretory vesicle-dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5-HT1B receptors located on CA1 pyramidal neurons. | The European journal of neuroscience 20030901 |
| Increased ventral striatal monoaminergic innervation in Tourette syndrome. | Neurology 20030812 |
| Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation. | Current opinion in neurology 20030801 |
| REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA. | Neurology 20030708 |
| Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA. | Neurology 20030708 |
| VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET. | Synapse (New York, N.Y.) 20030701 |
| Pharmacological management of tics in patients with TS. | Journal of psychosomatic research 20030701 |
| Tetrabenazine in the treatment of severe pediatric chorea. | Movement disorders : official journal of the Movement Disorder Society 20030601 |
| Effects of adrenal medulla graft on recovery of GABAergic and dopaminergic neuron deficits in mice: behavioural, pharmacological and immunohistochemical study. | Behavioural brain research 20030318 |
| Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression. | Brain research 20030307 |
| Successful therapy of tardive dyskinesia in a 71-year-old woman with a combination of tetrabenazine, olanzapine and tiapride. | International journal of clinical practice 20030301 |
| Gilles de la Tourette's syndrome. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20030301 |
| Psychopharmacological effects of tianeptine analogous hetero[2,1] benzothiazepine derivatives. | Arzneimittel-Forschung 20030101 |
| Classification and treatment of tardive syndromes. | The neurologist 20030101 |
| Self-biting induced by activation of L-type calcium channels in mice: dopaminergic influences. | Developmental neuroscience 20030101 |
| Non-synaptic release of [3H]noradrenaline in response to oxidative stress combined with mitochondrial dysfunction in rat hippocampal slices. | Neuroscience 20030101 |
| Evaluation of the central properties of several Hypericum species from the Canary Islands. | Phytotherapy research : PTR 20021201 |
| Elevated platelet vesicular monoamine transporter density in untreated patients diagnosed with major depression. | Psychiatry research 20021115 |
| Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001 |
| 1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged. | Life sciences 20020913 |
| Lack of effect of testosterone and dihydrotestosterone compared to 17beta-oestradiol in 1-methyl-4-phenyl-1,2,3,6, tetrahydropyridine-mice. | Journal of neuroendocrinology 20020901 |
| Catastrophic reactions induced by tetrabenazine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020901 |
| Increased platelet vesicular monoamine transporter density in adult schizophrenia patients. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801 |
| Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats. | Pharmacology, biochemistry, and behavior 20020701 |
| Effect of tetrabenazine on the striatal uptake of exogenous L-DOPA in vivo: a PET study in young and aged rhesus monkeys. | Synapse (New York, N.Y.) 20020615 |
| Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020601 |
| Human megakaryocytes cultured in vitro accumulate serotonin but not meta-iodobenzylguanidine whereas platelets concentrate both. | Experimental hematology 20020601 |
| Norepinephrine triggers Ca2+-dependent exocytosis of 5-hydroxytryptamine from rat pinealocytes in culture. | Journal of neurochemistry 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Hemiballismus. | Irish medical journal 20020401 |
| In vivo measures of dopaminergic radioligands in the rat brain: equilibrium infusion studies. | Synapse (New York, N.Y.) 20020301 |
| Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for neurotoxicity. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Phencyclidine increases vesicular dopamine uptake. | European journal of pharmacology 20020301 |
| [Herpetic encephalitis in childhood: a diagnosis which should not be forgotten]. | Revista de neurologia 20020201 |
| Antidepressant effects of the methanol extract of several Hypericum species from the Canary Islands. | Journal of ethnopharmacology 20020101 |
| Tetrabenazine fails to antagonize a behavioral effect of cocaine in rhesus monkeys. | Pharmacology, biochemistry, and behavior 20020101 |
| Tetrabenazine treatment for Huntington's disease-associated chorea. | Clinical neuropharmacology 20020101 |
| Dual-[11C]tracer single-acquisition positron emission tomography studies. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201 |
| Characterization of high-affinity [3H]TBZOH binding to the human platelet vesicular monoamine transporter. | Life sciences 20010928 |
| Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers. | Synapse (New York, N.Y.) 20010915 |
| Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors. | The Journal of pharmacology and experimental therapeutics 20010901 |
| Repetitive administration of tetrabenazine induces irreversible changes in locomotion and morphology of the substantia nigra in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010901 |
| Assessing the integrity of the dopamine system in Parkinson's disease: how best to do it? | Movement disorders : official journal of the Movement Disorder Society 20010901 |
| Interactions of 1-methyl-4-phenylpyridinium and other compounds with P-glycoprotein: relevance to toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | Brain research 20010810 |
| Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identifies transporter domains involved in tetrabenazine binding and substrate transport. | The Journal of biological chemistry 20010720 |
| Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2-propylaminopentane, ((-)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. | Bioorganic & medicinal chemistry 20010501 |
| Meige syndrome secondary to basal ganglia injury: a potential cause of acute respiratory distress. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20010501 |
| Hemichorea, moya-moya, and ulcerative colitis. | Movement disorders : official journal of the Movement Disorder Society 20010501 |
| Vesicular monoamine transporters heterologously expressed in the yeast Saccharomyces cerevisiae display high-affinity tetrabenazine binding. | Biochimica et biophysica acta 20010209 |
| [Spasmodic torticollis and vertebral hemangioma]. | Revista de neurologia 20010101 |
| Decreased densities of dopamine and serotonin transporters and of vesicular monoamine transporter 2 in severely kainic acid lesioned subregions of the striatum. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
| Pharmacological options for the treatment of Tourette's disorder. | Drugs 20010101 |
| Dyskinesia: L-dopa-induced and tardive dyskinesia. | Clinical neuropharmacology 20010101 |
| Reversal of tetrabenazine induced depression by selective noradrenaline (norepinephrine) reuptake inhibition. | Journal of neurology, neurosurgery, and psychiatry 19991001 |
| Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells. | The Journal of physiology 19990601 |
| Levodopa therapy can ameliorate tetrabenazine-induced parkinsonism. | Movement disorders : official journal of the Movement Disorder Society 19990101 |
| Peptide mapping of the [125I]Iodoazidoketanserin and [125I]2-N-[(3'-iodo-4'-azidophenyl)propionyl]tetrabenazine binding sites for the synaptic vesicle monoamine transporter. | The Journal of biological chemistry 19971010 |
| Long-term effects of tetrabenazine in hyperkinetic movement disorders. | Neurology 19970201 |
| Active transport of acetylcholine by the human vesicular acetylcholine transporter. | The Journal of biological chemistry 19961101 |
| Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter. | Proceedings of the National Academy of Sciences of the United States of America 19960514 |
| [Drug-induced dystonia misinterpreted as hysteria]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19960310 |
| Synaptic vesicular monoamine transporter expression: distribution and pharmacologic profile. | Brain research. Molecular brain research 19940301 |
| Bilateral akinesia in drug-induced parkinsonism after a subthalamic lesion. | Movement disorders : official journal of the Movement Disorder Society 19940101 |
| Functional identification and molecular cloning of a human brain vesicle monoamine transporter. | Journal of neurochemistry 19931201 |
| Expression cloning of a reserpine-sensitive vesicular monoamine transporter. | Proceedings of the National Academy of Sciences of the United States of America 19921115 |
| Adenosine release in morphine-induced hypotension in rats. | General pharmacology 19920101 |
| Coordinate and differential regulation of phenylethanolamine N-methyltransferase, tyrosine hydroxylase and proenkephalin mRNAs by neural and hormonal mechanisms in cultured bovine adrenal medullary cells. | Brain research 19900305 |
| [Behavioral pharmacological properties of the novel antidepressant paroxetine, a selective 5-HT uptake inhibitor]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19890901 |
| McN-5652: a highly potent inhibitor of serotonin uptake. | The Journal of pharmacology and experimental therapeutics 19881201 |
| [Behavioral effects of quinupramine, a new tricyclic antidepressant]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19880601 |
| Tetrabenazine therapy of dystonia, chorea, tics, and other dyskinesias. | Neurology 19880301 |
| Reserpine increases chromaffin cell enkephalin stores without a concomitant decrease in other proenkephalin-derived peptides. | Journal of neurochemistry 19871101 |
| Iatrogenic parkinsonism in Huntington's chorea. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19861201 |
| Pharmacology in vivo of the phenylindan derivative, Lu 19-005, a new potent inhibitor of dopamine, noradrenaline and 5-hydroxytryptamine uptake in rat brain. | Naunyn-Schmiedeberg's archives of pharmacology 19850401 |
| Tetrabenazine induces acute dystonic reactions. | Annals of neurology 19850201 |
| Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin. | Journal of medicinal chemistry 19840801 |
| Effects of dopamine agonists, catecholamine depletors, and cholinergic and GABAergic drugs on acute dyskinesias in squirrel monkeys. | Psychopharmacology 19840101 |
| Long-term treatment of tardive dyskinesia with presynaptically acting dopamine-depleting agents. | Advances in neurology 19830101 |
| (+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents. | Journal of medicinal chemistry 19820401 |
| Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCI-2016), a new psychotropic drug with antidepressant activity. | Arzneimittel-Forschung 19810101 |
| [Behavioral pharmacology of mianserin hydrochloride, a new antidepressant (author's transl)]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19800901 |
| [Biochemical study of the animal model depression induced by tetrabenazine (author's transl)]. | Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 19800101 |
| The influence of cerebral 5-hydroxytryptamine on catalepsy induced by brain-amine depleting neuroleptics or by cholinomimetics. | British journal of pharmacology 19791001 |
| 10-(Alkylamino)-4H-thieno[3,4-b][1,5]benzodiazepines. A novel class of potential neuroleptic agents. | Journal of medicinal chemistry 19790601 |
| Pharmacological and biochemical studies with three metabolites of nomifensine. | Psychopharmacology 19770131 |
| Tetrabenazine in the treatment of Huntington's chorea. | The Medical journal of Australia 19760417 |
| [Behavior pharmacology of maprotiline, a new antidepressant]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19751101 |
| Pharmacological analysis of a new anorexic substance: 5-hydroxy-5(4'-chlorophenyl)-2, 3-dihydro-5H-imidazo-(2, 1-a) isoindole (Mazindol). | Archives internationales de pharmacodynamie et de therapie 19750401 |
| Spontaneous oral dyskinesia. Results of treatment with tetrabenazine, pimozide, or both. | Archives of neurology 19741101 |
| A double-blind trial of tetrabenazine, thiopropazate, and placebo in patients with chorea. | Lancet (London, England) 19740126 |
| Treatment of involuntary movement disorders with tetrabenazine. | Journal of neurology, neurosurgery, and psychiatry 19720401 |
| Role of central dopaminergic receptors in manic response of cats to morphine. | Psychopharmacologia 19720101 |
| Persistent phenothiazine dyskinesia treated with tetrabenazine. | British medical journal 19711002 |
| Tetrabenazine for Huntington's chorea. | British medical journal 19701003 |
| [Mechanism of inversion by demethylimipramine of motor depression induced by tetrabenazine]. | Farmakologiia i toksikologiia 19690101 |
| The effect of tetrabenazine in some hyperkinetic syndromes. | Acta neurologica Scandinavica 19680101 |
Related Products
© 2019 Angene International Limited. All rights Reserved.