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Home > Other Building Blocks > 58-46-8
CAS No: 58-46-8 Catalog No: AG003UMF MDL No:MFCD00042740
Title | Journal |
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Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. | The Journal of pharmacology and experimental therapeutics 20170601 |
Randomized controlled trial of deutetrabenazine for tardive dyskinesia: The ARM-TD study. | Neurology 20170523 |
Dopamine depleters in the treatment of hyperkinetic movement disorders. | Expert opinion on pharmacotherapy 20161201 |
Deutetrabenazine for Treatment of Chorea in Huntington Disease. | JAMA 20160705 |
Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial. | JAMA 20160705 |
NBI-98854, a selective monoamine transport inhibitor for the treatment of tardive dyskinesia: A randomized, double-blind, placebo-controlled study. | Movement disorders : official journal of the Movement Disorder Society 20151001 |
Neuroleptic malignant syndrome induced by combination therapy with tetrabenazine and tiapride in a Japanese patient with Huntington's disease at the terminal stage of recurrent breast cancer. | Internal medicine (Tokyo, Japan) 20140101 |
Benign hereditary chorea: phenotype, prognosis, therapeutic outcome and long term follow-up in a large series with new mutations in the TITF1/NKX2-1 gene. | Journal of neurology, neurosurgery, and psychiatry 20121001 |
Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. | Molecular endocrinology (Baltimore, Md.) 20121001 |
Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([¹⁸F]AV-133) in a MPTP-lesioned PD mouse model. | Synapse (New York, N.Y.) 20120901 |
A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport. | Journal of neuroscience methods 20120815 |
Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology. | Neurology 20120807 |
Neuroferritinopathy: update on clinical features and pathogenesis. | Current drug targets 20120801 |
Heterogeneity of cholinergic denervation in Parkinson's disease without dementia. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120801 |
Effect of tetrabenazine on computerized dynamic posturography in Huntington disease patients. | Parkinsonism & related disorders 20120801 |
Management of status dystonicus in children. Cases report and review. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120701 |
Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature. | Clinical therapeutics 20120701 |
Comprehensive treatment of Huntington disease and other choreic disorders. | Cleveland Clinic journal of medicine 20120701 |
In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120601 |
Simple, rapid and reliable preparation of [¹¹C]-(+)-α-DTBZ of high quality for routine applications. | Molecules (Basel, Switzerland) 20120601 |
An evidence-based approach in the treatment of Huntington's disease. | Parkinsonism & related disorders 20120501 |
DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function. | Neurobiology of aging 20120401 |
Rapid improvement of tardive dyskinesia with tetrabenazine, clonazepam and clozapine combined: a naturalistic long-term follow-up study. | Journal of neurology 20120401 |
Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens. | Journal of neurochemistry 20120401 |
Canadian guidelines for the evidence-based treatment of tic disorders: pharmacotherapy. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20120301 |
Tetrabenazine augmentation in treatment-resistant schizophrenia: a 12-week, double-blind, placebo-controlled trial. | Journal of clinical psychopharmacology 20120201 |
In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in cocaine abusers. | The American journal of psychiatry 20120101 |
The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease. | Parkinson's disease 20120101 |
Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. | Neuro-degenerative diseases 20120101 |
Genetic mapping and exome sequencing identify variants associated with five novel diseases. | PloS one 20120101 |
Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
Anesthetic management of deep brain stimulator implantation in Meige's syndrome. | Journal of anaesthesiology, clinical pharmacology 20120101 |
No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease. | PloS one 20120101 |
Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview. | International journal of general medicine 20120101 |
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. | Substance abuse treatment, prevention, and policy 20120101 |
Update on the role of antipsychotics in the treatment of Tourette syndrome. | Neuropsychiatric disease and treatment 20120101 |
PET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133). | PloS one 20120101 |
Hyperosmolar non-ketotic hyperglycaemia: an important and reversible cause of acute bilateral ballismus. | BMJ case reports 20120101 |
Tetrabenazine treatment for stereotypies and tics associated with dementia. | The Journal of neuropsychiatry and clinical neurosciences 20120101 |
Sensory trick with metoclopramide-associated tardive tremor. | BMJ case reports 20120101 |
Improved working memory but no effect on striatal vesicular monoamine transporter type 2 after omega-3 polyunsaturated fatty acid supplementation. | PloS one 20120101 |
A concise synthesis of tetrabenazine: an intramolecular aza-Prins-type cyclization via oxidative C-H activation. | Organic letters 20111216 |
Tardive syndrome and Parkinson's disease responsive to concomitant tetrabenazine and levodopa therapy. | Parkinsonism & related disorders 20111201 |
Postthalamic stroke dystonic choreoathetosis responsive to tetrabenazine. | The Annals of pharmacotherapy 20111201 |
Tetrabenazine: for chorea associated with Huntington's disease. | CNS drugs 20111201 |
How best to address these common movement disorders. | The Journal of family practice 20111201 |
Use of Tetrabenazine in Huntington Disease Patients on Antidepressants or with Advanced Disease: Results from the TETRA-HD Study. | PLoS currents 20111113 |
Optimal scanning time window for 18F-FP-(+)-DTBZ (18F-AV-133) summed uptake measurements. | Nuclear medicine and biology 20111101 |
Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders. | Expert review of neurotherapeutics 20111101 |
Determination of the penetration of 9-fluoropropyl-(+)-dihydrotetrabenazine across the blood-brain barrier in rats by microdialysis combined with liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111015 |
An International Survey-based Algorithm for the Pharmacologic Treatment of Chorea in Huntington's Disease. | PLoS currents 20111011 |
Sigma receptor binding of tetrabenazine series tracers targeting VMAT2 in rat pancreas. | Nuclear medicine and biology 20111001 |
Altered affinity of the platelet vesicular monoamine transporter 2 to dihydrotetrabenazine in children with major depression. | Journal of neural transmission (Vienna, Austria : 1996) 20110901 |
Tetrabenazine inhibition of monoamine uptake and methamphetamine behavioral effects: locomotor activity, drug discrimination and self-administration. | Neuropharmacology 20110901 |
Therapeutic advances in the management of Huntington's disease. | The Yale journal of biology and medicine 20110901 |
Sex differences in methamphetamine toxicity in mice: effect on brain dopamine signaling pathways. | Psychoneuroendocrinology 20110801 |
Post pump chorea in a 77-year-old male. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110801 |
Leucoaraiosis, nigrostriatal denervation and motor symptoms in Parkinson's disease. | Brain : a journal of neurology 20110801 |
Platelet vesicular monoamine transporter 2 density in the disruptive behavior disorders. | Journal of child and adolescent psychopharmacology 20110801 |
Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry. | Medicinal research reviews 20110701 |
In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease. | Archives of neurology 20110701 |
Tardive dyskinesia. | Current treatment options in neurology 20110601 |
Synthesis and biological evaluation of 3-alkyl-dihydrotetrabenazine derivatives as vesicular monoamine transporter-2 (VMAT2) ligands. | Bioorganic & medicinal chemistry letters 20110601 |
Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography. | Brain : a journal of neurology 20110601 |
Age-specific progression of nigrostriatal dysfunction in Parkinson's disease. | Annals of neurology 20110501 |
Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors. | European journal of medicinal chemistry 20110501 |
Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY. | PLoS currents 20110413 |
European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. | European child & adolescent psychiatry 20110401 |
Tetrabenazine for the treatment of tardive dyskinesia. | The Annals of pharmacotherapy 20110401 |
Study the effect of a pseudo-carrier on pharmacokinetics of 9-fluoropropyl-(+)-dihydrotetrabenazine in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110301 |
Differential electrophysiological changes in striatal output neurons in Huntington's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110126 |
Tardive dyskinesia and other movement disorders secondary to aripiprazole. | Movement disorders : official journal of the Movement Disorder Society 20110101 |
Huntington's disease: From molecular basis to therapeutic advances. | The international journal of biochemistry & cell biology 20110101 |
Oral pharmacological treatment of X-linked dystonia parkinsonism: successes and failures. | The International journal of neuroscience 20110101 |
Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease. | PloS one 20110101 |
Management of Huntington's disease: role of tetrabenazine. | Therapeutics and clinical risk management 20110101 |
Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice. | PloS one 20110101 |
Hemiballismus. | Handbook of clinical neurology 20110101 |
Hyperglycemic nonketotic states and other metabolic imbalances. | Handbook of clinical neurology 20110101 |
Nonprimary dystonias. | Handbook of clinical neurology 20110101 |
Mcleod syndrome: Report of an Indian family with phenotypic heterogeneity. | Annals of Indian Academy of Neurology 20110101 |
Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review. | Journal of pharmacy & bioallied sciences 20110101 |
Vesicular monoamine transporter-1 (VMAT-1) mRNA and immunoreactive proteins in mouse brain. | Neuro endocrinology letters 20110101 |
Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease. | Frontiers in systems neuroscience 20110101 |
Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease. | Neurology research international 20110101 |
Tardive Meige's syndrome associated with olanzapine. | Annals of Indian Academy of Neurology 20110101 |
Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease. | Molecular neurodegeneration 20110101 |
Molecular imaging: a promising tool to monitor islet transplantation. | Journal of transplantation 20110101 |
Quadriparesis and dysarthria due to tetrabenazine therapy in a child with rheumatic chorea. | Indian journal of pharmacology 20110101 |
Long-stay psychiatric patients: a prospective study revealing persistent antipsychotic-induced movement disorder. | PloS one 20110101 |
Neuroacanthocytosis syndromes. | Orphanet journal of rare diseases 20110101 |
N-methyl D-aspartate receptor encephalitis: A new addition to the spectrum of autoimmune encephalitis. | Annals of Indian Academy of Neurology 20110101 |
Moving forward: advances in the treatment of movement disorders with deep brain stimulation. | Frontiers in integrative neuroscience 20110101 |
Dantrolene is neuroprotective in Huntington's disease transgenic mouse model. | Molecular neurodegeneration 20110101 |
[Medical aspects of the medical treatment in dystonia]. | Bulletin de l'Academie nationale de medecine 20110101 |
The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats. | The Journal of pharmacology and experimental therapeutics 20101201 |
Brain serotonergic circuitries. | Dialogues in clinical neuroscience 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Rat pancreas uptake of [11C]dihydrotetrabenazine stereoisomers. | Nuclear medicine and biology 20101101 |
Dramatic response of facial stereotype/tic to tetrabenazine in the first reported cases of neuroferritinopathy in the United States. | Movement disorders : official journal of the Movement Disorder Society 20101030 |
The effect of chronic methylphenidate administration on presynaptic dopaminergic parameters in a rat model for ADHD. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20101001 |
Effect of tetrabenazine use on restless legs syndrome. | Sleep medicine 20101001 |
Reserpine causes biphasic nociceptive sensitivity alteration in conjunction with brain biogenic amine tones in rats. | Neuroscience 20100915 |
Whole-body biodistribution and radiation dosimetry of 18F-FP-(+)-DTBZ (18F-AV-133): a novel vesicular monoamine transporter 2 imaging agent. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
11C-dihydrotetrabenazine beta-cell imaging. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901 |
Parkinson's disease and other movement disorders. | The American journal of geriatric pharmacotherapy 20100801 |
Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. | The American journal of geriatric pharmacotherapy 20100801 |
Drug safety monitoring in patients of movement disorders of a tertiary care hospital. | Indian journal of pharmacology 20100801 |
Tourette's Disorder. | Current treatment options in neurology 20100701 |
Coexisting huntingtin and SCA8 repeat expansion: case report of a severe complex neurodegenerative syndrome. | Journal of the neurological sciences 20100615 |
A case of secondary dystonia responding to levodopa. | Journal of child neurology 20100601 |
Influence of a low dose of amphetamine on vesicular monoamine transporter binding: a PET (+)[11C]DTBZ study in humans. | Synapse (New York, N.Y.) 20100601 |
Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An (18)F-DOPA and (11)C-DTBZ PET study. | Neurobiology of disease 20100601 |
Role of tetrabenazine for Huntington's disease-associated chorea. | The Annals of pharmacotherapy 20100601 |
A case of PANDAS treated with tetrabenazine and tonsillectomy. | Journal of child neurology 20100501 |
Binding characteristics of 9-fluoropropyl-(+)-dihydrotetrabenzazine (AV-133) to the vesicular monoamine transporter type 2 in rats. | Nuclear medicine and biology 20100501 |
In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease. | Nuclear medicine and biology 20100501 |
In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass. | Nuclear medicine and biology 20100401 |
Comparing fludeoxyglucose F18-PET assessment of regional cerebral glucose metabolism and [11C]dihydrotetrabenazine-PET in evaluation of early dementia and mild cognitive impairment. | Archives of neurology 20100401 |
Advances in the pharmacological management of Huntington's disease. | Drugs 20100326 |
Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter. | The Journal of biological chemistry 20100212 |
The utility of [(11)C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal-jejunal bypass. | Surgery 20100201 |
Dopamine transporter PET in normal aging: dopamine transporter decline and its possible role in preservation of motor function. | Synapse (New York, N.Y.) 20100201 |
Dysregulation of intracellular dopamine stores revealed in the R6/2 mouse striatum. | Journal of neurochemistry 20100201 |
In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100201 |
An improved radiosynthesis of [18F]AV-133: a PET imaging agent for vesicular monoamine transporter 2. | Nuclear medicine and biology 20100201 |
Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters. | Bioorganic & medicinal chemistry 20100115 |
In vivo [11C]dihydrotetrabenazine binding in rat striatum: sensitivity to dopamine concentrations. | Nuclear medicine and biology 20100101 |
Changes in clinical trials methodology over time: a systematic review of six decades of research in psychopharmacology. | PloS one 20100101 |
Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. | PloS one 20100101 |
Tetrabenazine is neuroprotective in Huntington's disease mice. | Molecular neurodegeneration 20100101 |
Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease. | Neuropsychiatric disease and treatment 20100101 |
Extrastriatal dopaminergic circuits of the Basal Ganglia. | Frontiers in neuroanatomy 20100101 |
Huntington's disease: a clinical review. | Orphanet journal of rare diseases 20100101 |
Hot tongue on FDG PET scan in a patient of Hodgkin's lymphoma undergoing antipsychotic treatment. | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India 20100101 |
Dysphagia due to tardive dyskinesia. | Industrial psychiatry journal 20100101 |
Oro-mandibular dystonia. | National journal of maxillofacial surgery 20100101 |
Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2). | Journal of medicinal chemistry 20091210 |
Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter. | Journal of neural transmission (Vienna, Austria : 1996) 20091201 |
Tetrabenazine. | Expert opinion on pharmacotherapy 20091201 |
MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. | Neurotoxicology 20091101 |
Synthesis and evaluation of 2-amino-dihydrotetrabenzine derivatives as probes for imaging vesicular monoamine transporter-2. | Bioorganic & medicinal chemistry letters 20090901 |
Treatment of hyperkinetic movement disorders. | The Lancet. Neurology 20090901 |
Treating complex movement disorders in children with cerebral palsy. | The Ulster medical journal 20090901 |
Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues. | The Journal of organic chemistry 20090821 |
New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification. | NeuroImage 20090815 |
Pelvic dyskinesia with an outstanding response to tetrabenazine. | Progress in neuro-psychopharmacology & biological psychiatry 20090801 |
Visualizing vesicular dopamine dynamics in Parkinson's disease. | Synapse (New York, N.Y.) 20090801 |
[Choreoathetosis after Herpes simplex encephalitis]. | Anales de pediatria (Barcelona, Spain : 2003) 20090801 |
Therapeutic interventions for symptomatic treatment in Huntington's disease. | The Cochrane database of systematic reviews 20090708 |
Signal separation and parameter estimation in noninvasive dual-tracer PET scans using reference-region approaches. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090701 |
Noninvasive imaging of pancreatic beta cells. | Nature reviews. Endocrinology 20090701 |
Dopamine signaling is required for depolarization-induced slow current in cerebellar Purkinje cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090701 |
Treatment of chorea associated with Huntington's disease: focus on tetrabenazine. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20090701 |
Wilson's disease--a rare psychiatric presentation. | Journal of the Indian Medical Association 20090701 |
Measurement of plasmalemmal dopamine transport, vesicular dopamine transport, and K(+)-stimulated dopamine release in frozen rat brain tissue. | Journal of neuroscience methods 20090615 |
New drugs 09, part 2. | Nursing 20090601 |
Aplysinopsins--marine indole alkaloids: chemistry, bioactivity and ecological significance. | Marine drugs 20090601 |
Asymmetric synthesis of tetrabenazine and dihydrotetrabenazine. | The Journal of organic chemistry 20090515 |
Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes. | Parkinsonism & related disorders 20090501 |
Paroxysmal dyskinesias. | Current treatment options in neurology 20090501 |
[Therapeutic use of tetrabenazine]. | Revista de neurologia 20090501 |
Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome. | Neurology 20090421 |
PET demonstrates reduced dopamine transporter expression in PD with dyskinesias. | Neurology 20090407 |
Dyskinesia in Parkinson disease: back for the future? | Neurology 20090407 |
Pancreatic imaging with 11C-dihydrotetrabenazine PET: a perspective. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301 |
11C-dihydrotetrabenazine PET of the pancreas in subjects with long-standing type 1 diabetes and in healthy controls. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301 |
Tetrabenazine (Xenazine) for Huntington's chorea. | The Medical letter on drugs and therapeutics 20090126 |
Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine. | Movement disorders : official journal of the Movement Disorder Society 20090115 |
Tetrabenazine. | Nature reviews. Drug discovery 20090101 |
Hypertensive crisis and cheese. | Indian journal of psychiatry 20090101 |
Treatment of Tardive Dyskinesia by tetrabenazine, clonazepam and vitamin E. | Indian journal of psychiatry 20090101 |
Chorea-ballismus in acute non-ketotic hyperglycaemia. | Functional neurology 20090101 |
Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators. | BMC neurology 20090101 |
Amoxapine-induced tardive dyskinesia. | Indian journal of psychiatry 20090101 |
Movement disorder: a manifestation of HIV and its response to therapy. | Neurology India 20090101 |
Olanzapine induced tardive dystonia in case of adolescent bipolar disorder. | Journal of pediatric neurosciences 20090101 |
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism. | Journal of neurochemistry 20081201 |
Tetrabenazine (Xenazine), An FDA-Approved Treatment Option For Huntington's Disease-Related Chorea. | P & T : a peer-reviewed journal for formulary management 20081201 |
Dopamine modulating drugs influence striatal (+)-[11C]DTBZ binding in rats: VMAT2 binding is sensitive to changes in vesicular dopamine concentration. | Synapse (New York, N.Y.) 20081101 |
Increased beta activity in dystonia patients after drug-induced dopamine deficiency. | Experimental neurology 20081101 |
In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine. | Nuclear medicine and biology 20081101 |
Gene therapy offers HD patients relief from some symptoms. Tetrabenazine inhibits the transport of a molecule called vesicular monoamine transporter type 2 or VMAT2. | Managed care (Langhorne, Pa.) 20081101 |
Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924 |
Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists. | Bioorganic & medicinal chemistry letters 20080915 |
Anterocollis: clinical features and treatment options. | Medical science monitor : international medical journal of experimental and clinical research 20080901 |
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. | Current neuropharmacology 20080901 |
Psychopharmacology of tic disorders. | Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent 20080801 |
In vivo imaging of beta-cell mass in rats using 18F-FP-(+)-DTBZ: a potential PET ligand for studying diabetes mellitus. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080701 |
Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine. | The Journal of endocrinology 20080701 |
Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine. | Journal of neurochemistry 20080601 |
Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. | Journal of neurochemistry 20080601 |
Camptocormia: a rare axial myopathy disease. | Clinics (Sao Paulo, Brazil) 20080601 |
Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography. | Psychiatry research 20080530 |
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. | Human molecular genetics 20080515 |
Treatment of tardive dyskinesia with levetiracetam in a transplant patient. | Acta neurologica Scandinavica 20080501 |
[Severe generalized dystonia due to postradiotherapy cerebral calcifications]. | Revue neurologique 20080501 |
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. | Journal of neurochemistry 20080401 |
Whole body [11C]-dihydrotetrabenazine imaging of baboons: biodistribution and human radiation dosimetry estimates. | European journal of nuclear medicine and molecular imaging 20080401 |
Comparison of weight gain in treatments for Tourette syndrome: tetrabenazine versus neuroleptic drugs. | Journal of child neurology 20080401 |
Expression and function of the rat vesicular monoamine transporter 2. | American journal of physiology. Cell physiology 20080401 |
Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease. | Annals of neurology 20080301 |
[A comparison of the pharmacology of (-)-deprenyl to N-methylpropargylamine-1-aminoindane (J-508) and rasagiline, the desmethyl-analogue of J-508]. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080301 |
Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study. | Journal of medicinal chemistry 20080227 |
[Quick and simple synthesis of (11)C-(+)-alpha-dihydrotetrabenazine to be used as a PET radioligand of vesicular monoamine transporters]. | Revista espanola de medicina nuclear 20080101 |
[Use of 11C-(+)-alpha -dihydrotetrabenazine for the assessment of dopaminergic innervation in animal models of Parkinson's disease]. | Revista espanola de medicina nuclear 20080101 |
A study of chorea after tetrabenazine withdrawal in patients with Huntington disease. | Clinical neuropharmacology 20080101 |
Tourette's syndrome and role of tetrabenazine: review and personal experience. | Clinical drug investigation 20080101 |
Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20080101 |
New drugs: Clevidipine butyrate, difluprednate, and tetrabenazine. | Journal of the American Pharmacists Association : JAPhA 20080101 |
The long-term effect of tetrabenazine in the management of Huntington disease. | Clinical neuropharmacology 20080101 |
Normal dopaminergic nigrostriatal innervation in SPG3A hereditary spastic paraplegia. | Journal of neurogenetics 20080101 |
Identification of the substrate binding region of vesicular monoamine transporter-2 (VMAT-2) using iodoaminoflisopolol as a novel photoprobe. | Molecular pharmacology 20071201 |
Neurotransmitter depleter tetrabenazine; potential candidate for schizophrenia treatment? | Schizophrenia research 20071101 |
PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071001 |
Tetrabenazine in the treatment of Huntington's disease. | Neuropsychiatric disease and treatment 20071001 |
Drug-induced tardive motor syndromes. | Psychiatrike = Psychiatriki 20071001 |
Specific derivatization of the vesicle monoamine transporter with novel carrier-free radioiodinated reserpine and tetrabenazine photoaffinity labels. | Analytical biochemistry 20070801 |
Dopaminergic signaling and striatal neurodegeneration in Huntington's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070725 |
Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP. | Toxicology letters 20070710 |
In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070701 |
Reduced platelet vesicular monoamine transporter density in Tourette's syndrome pediatric male patients. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070701 |
Antidepressant activity of some Hypericum reflexum L. fil. extracts in the forced swimming test in mice. | Journal of ethnopharmacology 20070530 |
Vesicular monoamine transporter 1 mediates dopamine secretion in rat proximal tubular cells. | American journal of physiology. Renal physiology 20070501 |
Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2. | Bioorganic & medicinal chemistry 20070415 |
Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain. | Nuclear medicine and biology 20070401 |
Characterization of optically resolved 9-fluoropropyl-dihydrotetrabenazine as a potential PET imaging agent targeting vesicular monoamine transporters. | Nuclear medicine and biology 20070401 |
Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. | Neurology 20070306 |
A systematic review of the treatment studies in Huntington's disease since 1990. | Expert opinion on pharmacotherapy 20070201 |
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Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population. | Behavioral and brain functions : BBF 20060101 |
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Treatment with the new antipsychotic sertindole for late-occurring undesirable movement effects. | International clinical psychopharmacology 20051101 |
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Antidepressant properties of some Hypericum canariense L. and Hypericum glandulosum Ait. extracts in the forced swimming test in mice. | Journal of ethnopharmacology 20050321 |
Decreased platelet vesicular monoamine transporter density in children and adolescents with attention deficit/hyperactivity disorder. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301 |
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Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters. | The Journal of pharmacology and experimental therapeutics 20040901 |
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Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040701 |
Long-term reproducibility of in vivo measures of specific binding of radioligands in rat brain. | Nuclear medicine and biology 20040701 |
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Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. | Brain research 20031107 |
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Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001 |
Endogenous 5-HT, released by MDMA through serotonin transporter- and secretory vesicle-dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5-HT1B receptors located on CA1 pyramidal neurons. | The European journal of neuroscience 20030901 |
Increased ventral striatal monoaminergic innervation in Tourette syndrome. | Neurology 20030812 |
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REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA. | Neurology 20030708 |
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Pharmacological management of tics in patients with TS. | Journal of psychosomatic research 20030701 |
Tetrabenazine in the treatment of severe pediatric chorea. | Movement disorders : official journal of the Movement Disorder Society 20030601 |
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Evaluation of the central properties of several Hypericum species from the Canary Islands. | Phytotherapy research : PTR 20021201 |
Elevated platelet vesicular monoamine transporter density in untreated patients diagnosed with major depression. | Psychiatry research 20021115 |
Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001 |
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Catastrophic reactions induced by tetrabenazine. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020901 |
Increased platelet vesicular monoamine transporter density in adult schizophrenia patients. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats. | Pharmacology, biochemistry, and behavior 20020701 |
Effect of tetrabenazine on the striatal uptake of exogenous L-DOPA in vivo: a PET study in young and aged rhesus monkeys. | Synapse (New York, N.Y.) 20020615 |
Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020601 |
Human megakaryocytes cultured in vitro accumulate serotonin but not meta-iodobenzylguanidine whereas platelets concentrate both. | Experimental hematology 20020601 |
Norepinephrine triggers Ca2+-dependent exocytosis of 5-hydroxytryptamine from rat pinealocytes in culture. | Journal of neurochemistry 20020501 |
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In vivo measures of dopaminergic radioligands in the rat brain: equilibrium infusion studies. | Synapse (New York, N.Y.) 20020301 |
Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for neurotoxicity. | The Journal of pharmacology and experimental therapeutics 20020301 |
Phencyclidine increases vesicular dopamine uptake. | European journal of pharmacology 20020301 |
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Antidepressant effects of the methanol extract of several Hypericum species from the Canary Islands. | Journal of ethnopharmacology 20020101 |
Tetrabenazine fails to antagonize a behavioral effect of cocaine in rhesus monkeys. | Pharmacology, biochemistry, and behavior 20020101 |
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Dual-[11C]tracer single-acquisition positron emission tomography studies. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201 |
Characterization of high-affinity [3H]TBZOH binding to the human platelet vesicular monoamine transporter. | Life sciences 20010928 |
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Repetitive administration of tetrabenazine induces irreversible changes in locomotion and morphology of the substantia nigra in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010901 |
Assessing the integrity of the dopamine system in Parkinson's disease: how best to do it? | Movement disorders : official journal of the Movement Disorder Society 20010901 |
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Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identifies transporter domains involved in tetrabenazine binding and substrate transport. | The Journal of biological chemistry 20010720 |
Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2-propylaminopentane, ((-)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. | Bioorganic & medicinal chemistry 20010501 |
Meige syndrome secondary to basal ganglia injury: a potential cause of acute respiratory distress. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20010501 |
Hemichorea, moya-moya, and ulcerative colitis. | Movement disorders : official journal of the Movement Disorder Society 20010501 |
Vesicular monoamine transporters heterologously expressed in the yeast Saccharomyces cerevisiae display high-affinity tetrabenazine binding. | Biochimica et biophysica acta 20010209 |
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Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells. | The Journal of physiology 19990601 |
Levodopa therapy can ameliorate tetrabenazine-induced parkinsonism. | Movement disorders : official journal of the Movement Disorder Society 19990101 |
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Expression cloning of a reserpine-sensitive vesicular monoamine transporter. | Proceedings of the National Academy of Sciences of the United States of America 19921115 |
Adenosine release in morphine-induced hypotension in rats. | General pharmacology 19920101 |
Coordinate and differential regulation of phenylethanolamine N-methyltransferase, tyrosine hydroxylase and proenkephalin mRNAs by neural and hormonal mechanisms in cultured bovine adrenal medullary cells. | Brain research 19900305 |
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Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin. | Journal of medicinal chemistry 19840801 |
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Treatment of involuntary movement disorders with tetrabenazine. | Journal of neurology, neurosurgery, and psychiatry 19720401 |
Role of central dopaminergic receptors in manic response of cats to morphine. | Psychopharmacologia 19720101 |
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